Stem definition | Drug id | CAS RN |
---|---|---|
selective cyclo-oxygenase inhibitors | 568 | 169590-42-5 |
Dose | Unit | Route |
---|---|---|
0.20 | g | O |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 2 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 0.01 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 2 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 17.49 µM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
Date | Agency | Company | Orphan |
---|---|---|---|
Dec. 31, 1998 | FDA | GD SEARLE |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug hypersensitivity | 1528.67 | 9.70 | 2699 | 140320 | 241126 | 46301917 |
Rheumatoid arthritis | 651.52 | 9.70 | 1909 | 141110 | 238306 | 46304737 |
Drug ineffective | 570.60 | 9.70 | 3779 | 139240 | 674059 | 45868984 |
Arthralgia | 402.16 | 9.70 | 2185 | 140834 | 362418 | 46180625 |
Death | 291.78 | 9.70 | 360 | 142659 | 335188 | 46207855 |
Therapeutic product effect decreased | 227.32 | 9.70 | 661 | 142358 | 81940 | 46461103 |
Toxicity to various agents | 220.06 | 9.70 | 195 | 142824 | 211571 | 46331472 |
Musculoskeletal stiffness | 219.53 | 9.70 | 730 | 142289 | 97263 | 46445780 |
Loss of personal independence in daily activities | 219.20 | 9.70 | 518 | 142501 | 56665 | 46486378 |
Completed suicide | 202.24 | 9.70 | 97 | 142922 | 145823 | 46397220 |
Pain | 182.54 | 9.70 | 2245 | 140774 | 474703 | 46068340 |
Maternal exposure during pregnancy | 181.96 | 9.70 | 45 | 142974 | 102504 | 46440539 |
Osteoarthritis | 161.68 | 9.70 | 487 | 142532 | 61538 | 46481505 |
Drug intolerance | 159.72 | 9.70 | 879 | 142140 | 146170 | 46396873 |
Therapeutic product effect incomplete | 156.48 | 9.70 | 561 | 142458 | 77592 | 46465451 |
Pain in extremity | 152.15 | 9.70 | 1330 | 141689 | 257350 | 46285693 |
Exposure during pregnancy | 148.27 | 9.70 | 73 | 142946 | 108139 | 46434904 |
Neutropenia | 141.41 | 9.70 | 138 | 142881 | 143066 | 46399977 |
Drug abuse | 133.54 | 9.70 | 18 | 143001 | 63390 | 46479653 |
Febrile neutropenia | 129.38 | 9.70 | 64 | 142955 | 94563 | 46448480 |
Condition aggravated | 129.34 | 9.70 | 1231 | 141788 | 243821 | 46299222 |
Arthropathy | 128.28 | 9.70 | 557 | 142462 | 84143 | 46458900 |
Joint swelling | 123.26 | 9.70 | 901 | 142118 | 165172 | 46377871 |
Contraindicated product administered | 112.95 | 9.70 | 515 | 142504 | 79432 | 46463611 |
Bedridden | 111.53 | 9.70 | 139 | 142880 | 9020 | 46534023 |
Arthritis | 111.43 | 9.70 | 501 | 142518 | 76815 | 46466228 |
Gait inability | 110.84 | 9.70 | 296 | 142723 | 34907 | 46508136 |
Pharyngitis | 108.52 | 9.70 | 194 | 142825 | 17389 | 46525654 |
Ankylosing spondylitis | 108.41 | 9.70 | 118 | 142901 | 6619 | 46536424 |
Toothache | 101.04 | 9.70 | 182 | 142837 | 16410 | 46526633 |
Intentional overdose | 98.13 | 9.70 | 38 | 142981 | 64906 | 46478137 |
Fibromyalgia | 91.89 | 9.70 | 283 | 142736 | 36180 | 46506863 |
Thrombocytopenia | 91.75 | 9.70 | 154 | 142865 | 126427 | 46416616 |
Gait disturbance | 90.53 | 9.70 | 757 | 142262 | 144506 | 46398537 |
Foot deformity | 88.62 | 9.70 | 165 | 142854 | 15260 | 46527783 |
Pemphigus | 88.19 | 9.70 | 16 | 143003 | 45258 | 46497785 |
Hyponatraemia | 84.38 | 9.70 | 112 | 142907 | 101220 | 46441823 |
Pleural fibrosis | 84.25 | 9.70 | 77 | 142942 | 3492 | 46539551 |
Immobile | 83.57 | 9.70 | 86 | 142933 | 4520 | 46538523 |
Acute kidney injury | 83.44 | 9.70 | 405 | 142614 | 235450 | 46307593 |
Presbyacusis | 82.98 | 9.70 | 69 | 142950 | 2753 | 46540290 |
International normalised ratio fluctuation | 82.51 | 9.70 | 62 | 142957 | 2131 | 46540912 |
C-reactive protein abnormal | 80.70 | 9.70 | 192 | 142827 | 21078 | 46521965 |
Hypotension | 77.93 | 9.70 | 407 | 142612 | 232182 | 46310861 |
Osteoporosis | 76.58 | 9.70 | 286 | 142733 | 40322 | 46502721 |
Thyroid neoplasm | 74.84 | 9.70 | 73 | 142946 | 3596 | 46539447 |
Hypoaesthesia | 73.25 | 9.70 | 618 | 142401 | 118251 | 46424792 |
Blood magnesium increased | 72.81 | 9.70 | 66 | 142953 | 2961 | 46540082 |
White blood cell count abnormal | 72.50 | 9.70 | 84 | 142935 | 5048 | 46537995 |
Overdose | 72.12 | 9.70 | 126 | 142893 | 101853 | 46441190 |
Pleural thickening | 71.26 | 9.70 | 61 | 142958 | 2534 | 46540509 |
Myocardial infarction | 71.04 | 9.70 | 527 | 142492 | 97001 | 46446042 |
Electrocardiogram QT prolonged | 69.70 | 9.70 | 35 | 142984 | 51290 | 46491753 |
Red blood cell sedimentation rate increased | 69.57 | 9.70 | 190 | 142829 | 22699 | 46520344 |
Foot fracture | 68.16 | 9.70 | 171 | 142848 | 19411 | 46523632 |
Bone swelling | 67.98 | 9.70 | 44 | 142975 | 1184 | 46541859 |
Lower limb fracture | 65.52 | 9.70 | 128 | 142891 | 12270 | 46530773 |
Dyspnoea | 64.20 | 9.70 | 1153 | 141866 | 514395 | 46028648 |
Deafness neurosensory | 62.56 | 9.70 | 73 | 142946 | 4421 | 46538622 |
Psoriatic arthropathy | 61.89 | 9.70 | 248 | 142771 | 36131 | 46506912 |
Neoplasm malignant | 61.65 | 9.70 | 185 | 142834 | 23314 | 46519729 |
Mobility decreased | 58.97 | 9.70 | 352 | 142667 | 60242 | 46482801 |
Interstitial lung disease | 57.46 | 9.70 | 321 | 142698 | 53628 | 46489415 |
Anaemia | 56.55 | 9.70 | 506 | 142513 | 255273 | 46287770 |
Epigastric discomfort | 56.39 | 9.70 | 78 | 142941 | 5606 | 46537437 |
Hypermobility syndrome | 54.83 | 9.70 | 31 | 142988 | 648 | 46542395 |
Deformity | 53.95 | 9.70 | 87 | 142932 | 7170 | 46535873 |
Pulmonary toxicity | 53.61 | 9.70 | 69 | 142950 | 4624 | 46538419 |
Hypokalaemia | 53.39 | 9.70 | 119 | 142900 | 87905 | 46455138 |
Suicide attempt | 53.16 | 9.70 | 54 | 142965 | 54982 | 46488061 |
Confusional state | 52.27 | 9.70 | 282 | 142737 | 159610 | 46383433 |
Seizure | 52.24 | 9.70 | 197 | 142822 | 122857 | 46420186 |
Abortion spontaneous | 50.50 | 9.70 | 36 | 142983 | 43610 | 46499433 |
Dry eye | 50.21 | 9.70 | 205 | 142814 | 30117 | 46512926 |
Cardio-respiratory arrest | 50.00 | 9.70 | 66 | 142953 | 59803 | 46483240 |
Plasma cell myeloma | 49.77 | 9.70 | 38 | 142981 | 44440 | 46498603 |
Osteopenia | 49.77 | 9.70 | 139 | 142880 | 16822 | 46526221 |
Drug eruption | 49.56 | 9.70 | 161 | 142858 | 21168 | 46521875 |
Nerve injury | 48.81 | 9.70 | 86 | 142933 | 7619 | 46535424 |
Burning mouth syndrome | 48.17 | 9.70 | 24 | 142995 | 384 | 46542659 |
Hypoglycaemia | 47.37 | 9.70 | 58 | 142961 | 54291 | 46488752 |
Bone cyst | 45.99 | 9.70 | 43 | 142976 | 2008 | 46541035 |
Premature delivery | 44.75 | 9.70 | 7 | 143012 | 22062 | 46520981 |
Intervertebral disc protrusion | 44.71 | 9.70 | 151 | 142868 | 20254 | 46522789 |
Dehydration | 44.43 | 9.70 | 296 | 142723 | 159244 | 46383799 |
Sepsis | 44.38 | 9.70 | 240 | 142779 | 135774 | 46407269 |
Joint stiffness | 43.88 | 9.70 | 182 | 142837 | 26926 | 46516117 |
Syncope | 43.69 | 9.70 | 169 | 142850 | 104634 | 46438409 |
Glossodynia | 43.47 | 9.70 | 43 | 142976 | 44330 | 46498713 |
Gastric disorder | 43.00 | 9.70 | 179 | 142840 | 26526 | 46516517 |
Rheumatoid nodule | 42.75 | 9.70 | 89 | 142930 | 8931 | 46534112 |
Disease progression | 42.18 | 9.70 | 141 | 142878 | 91159 | 46451884 |
Intentional self-injury | 42.07 | 9.70 | 11 | 143008 | 24155 | 46518888 |
Epicondylitis | 41.94 | 9.70 | 38 | 142981 | 1704 | 46541339 |
Sopor | 40.86 | 9.70 | 6 | 143013 | 19822 | 46523221 |
Osteosclerosis | 40.65 | 9.70 | 52 | 142967 | 3464 | 46539579 |
Musculoskeletal pain | 40.24 | 9.70 | 359 | 142660 | 69769 | 46473274 |
Nephrolithiasis | 40.20 | 9.70 | 204 | 142815 | 32847 | 46510196 |
Red blood cell sedimentation rate abnormal | 40.18 | 9.70 | 112 | 142907 | 13537 | 46529506 |
Fine motor skill dysfunction | 40.09 | 9.70 | 53 | 142966 | 3647 | 46539396 |
Bloody discharge | 39.49 | 9.70 | 29 | 142990 | 962 | 46542081 |
Pulmonary arterial hypertension | 39.44 | 9.70 | 15 | 143004 | 25913 | 46517130 |
Exostosis | 39.31 | 9.70 | 93 | 142926 | 10170 | 46532873 |
Vomiting | 38.95 | 9.70 | 1073 | 141946 | 451721 | 46091322 |
Cyst | 38.33 | 9.70 | 102 | 142917 | 11998 | 46531045 |
Pyrexia | 38.12 | 9.70 | 797 | 142222 | 348005 | 46195038 |
Rotator cuff syndrome | 38.08 | 9.70 | 99 | 142920 | 11484 | 46531559 |
Multiple sclerosis relapse | 37.73 | 9.70 | 44 | 142975 | 42081 | 46500962 |
Disability | 37.73 | 9.70 | 91 | 142928 | 10076 | 46532967 |
Nasopharyngitis | 37.65 | 9.70 | 672 | 142347 | 153326 | 46389717 |
Cardiac arrest | 37.53 | 9.70 | 146 | 142873 | 90253 | 46452790 |
Impaired work ability | 37.51 | 9.70 | 104 | 142915 | 12532 | 46530511 |
Ulcer | 37.49 | 9.70 | 128 | 142891 | 17264 | 46525779 |
Spinal stenosis | 37.00 | 9.70 | 103 | 142916 | 12440 | 46530603 |
Metabolic acidosis | 36.38 | 9.70 | 39 | 142980 | 38741 | 46504302 |
Premature baby | 36.15 | 9.70 | 6 | 143013 | 18106 | 46524937 |
Off label use | 36.12 | 9.70 | 887 | 142132 | 378954 | 46164089 |
Hospitalisation | 35.78 | 9.70 | 89 | 142930 | 63296 | 46479747 |
Tachycardia | 35.78 | 9.70 | 170 | 142849 | 99452 | 46443591 |
Mucosal inflammation | 35.68 | 9.70 | 40 | 142979 | 38936 | 46504107 |
Intervertebral disc degeneration | 35.39 | 9.70 | 105 | 142914 | 13147 | 46529896 |
Right ventricular failure | 35.26 | 9.70 | 4 | 143015 | 16089 | 46526954 |
Decreased appetite | 35.11 | 9.70 | 402 | 142617 | 193434 | 46349609 |
Leukopenia | 34.78 | 9.70 | 101 | 142918 | 68242 | 46474801 |
Pharyngeal oedema | 34.31 | 9.70 | 110 | 142909 | 14361 | 46528682 |
Infection | 34.09 | 9.70 | 587 | 142432 | 133005 | 46410038 |
Anaphylactic reaction | 33.67 | 9.70 | 278 | 142741 | 52834 | 46490209 |
Investigation abnormal | 33.66 | 9.70 | 27 | 142992 | 1023 | 46542020 |
Fracture | 33.58 | 9.70 | 119 | 142900 | 16352 | 46526691 |
Encephalopathy | 33.54 | 9.70 | 32 | 142987 | 33557 | 46509486 |
Respiratory failure | 33.35 | 9.70 | 163 | 142856 | 94653 | 46448390 |
Asthenia | 33.33 | 9.70 | 713 | 142306 | 310362 | 46232681 |
Treatment failure | 33.09 | 9.70 | 433 | 142586 | 92654 | 46450389 |
Joint injury | 32.70 | 9.70 | 131 | 142888 | 19078 | 46523965 |
Pancytopenia | 32.42 | 9.70 | 142 | 142877 | 84916 | 46458127 |
Bradycardia | 32.28 | 9.70 | 100 | 142919 | 66198 | 46476845 |
Multiple organ dysfunction syndrome | 32.09 | 9.70 | 69 | 142950 | 51641 | 46491402 |
Diarrhoea | 31.31 | 9.70 | 1399 | 141620 | 558203 | 45984840 |
Antinuclear antibody positive | 30.98 | 9.70 | 63 | 142956 | 6217 | 46536826 |
Product dose omission issue | 30.71 | 9.70 | 349 | 142670 | 168171 | 46374872 |
Stress | 30.65 | 9.70 | 266 | 142753 | 51285 | 46491758 |
Pregnancy | 30.59 | 9.70 | 23 | 142996 | 27114 | 46515929 |
Product use in unapproved indication | 30.15 | 9.70 | 158 | 142861 | 90115 | 46452928 |
Movement disorder | 29.56 | 9.70 | 116 | 142903 | 16733 | 46526310 |
Fluid overload | 29.43 | 9.70 | 24 | 142995 | 27161 | 46515882 |
Device dislocation | 29.40 | 9.70 | 15 | 143004 | 21787 | 46521256 |
Systemic lupus erythematosus | 29.19 | 9.70 | 102 | 142917 | 65078 | 46477965 |
Hypoxia | 29.09 | 9.70 | 73 | 142946 | 51765 | 46491278 |
Lyme disease | 28.99 | 9.70 | 36 | 142983 | 2327 | 46540716 |
Spinal osteoarthritis | 28.64 | 9.70 | 102 | 142917 | 14049 | 46528994 |
Gastric ulcer | 28.04 | 9.70 | 137 | 142882 | 21726 | 46521317 |
Acute myeloid leukaemia | 27.82 | 9.70 | 7 | 143012 | 15771 | 46527272 |
Upper limb fracture | 27.42 | 9.70 | 108 | 142911 | 15605 | 46527438 |
Neck pain | 27.18 | 9.70 | 274 | 142745 | 55032 | 46488011 |
Fatigue | 26.70 | 9.70 | 1560 | 141459 | 607137 | 45935906 |
Torsade de pointes | 26.68 | 9.70 | 3 | 143016 | 12151 | 46530892 |
Somnolence | 26.65 | 9.70 | 329 | 142690 | 156192 | 46386851 |
Gastric ulcer haemorrhage | 26.63 | 9.70 | 51 | 142968 | 4817 | 46538226 |
Malignant neoplasm progression | 26.22 | 9.70 | 106 | 142913 | 64820 | 46478223 |
Bunion operation | 26.15 | 9.70 | 21 | 142998 | 797 | 46542246 |
Anti-cyclic citrullinated peptide antibody positive | 26.07 | 9.70 | 13 | 143006 | 19132 | 46523911 |
Meniscus injury | 25.92 | 9.70 | 57 | 142962 | 5939 | 46537104 |
Back disorder | 25.92 | 9.70 | 74 | 142945 | 9067 | 46533976 |
Septic shock | 25.66 | 9.70 | 91 | 142928 | 57802 | 46485241 |
Peripheral swelling | 25.40 | 9.70 | 649 | 142370 | 157422 | 46385621 |
Epistaxis | 25.33 | 9.70 | 106 | 142913 | 64199 | 46478844 |
Cytomegalovirus infection | 25.19 | 9.70 | 12 | 143007 | 18132 | 46524911 |
Musculoskeletal disorder | 24.87 | 9.70 | 104 | 142915 | 15441 | 46527602 |
Paranasal sinus inflammation | 24.63 | 9.70 | 13 | 143006 | 236 | 46542807 |
Mental status changes | 24.33 | 9.70 | 50 | 142969 | 38038 | 46505005 |
White blood cell count decreased | 24.32 | 9.70 | 223 | 142796 | 112008 | 46431035 |
Platelet count decreased | 24.25 | 9.70 | 193 | 142826 | 99831 | 46443212 |
Dermatitis allergic | 23.95 | 9.70 | 89 | 142930 | 12514 | 46530529 |
Impaired healing | 23.65 | 9.70 | 193 | 142826 | 36550 | 46506493 |
Cholestasis | 23.12 | 9.70 | 29 | 142990 | 26864 | 46516179 |
Bursitis | 23.10 | 9.70 | 121 | 142898 | 19721 | 46523322 |
C-reactive protein increased | 22.72 | 9.70 | 277 | 142742 | 58313 | 46484730 |
Neuropathy peripheral | 22.67 | 9.70 | 174 | 142845 | 90719 | 46452324 |
Neutropenic sepsis | 22.65 | 9.70 | 5 | 143014 | 12319 | 46530724 |
Epilepsy | 22.12 | 9.70 | 24 | 142995 | 23714 | 46519329 |
Premature labour | 21.99 | 9.70 | 4 | 143015 | 11295 | 46531748 |
Loss of employment | 21.97 | 9.70 | 23 | 142996 | 1233 | 46541810 |
Respiratory arrest | 21.93 | 9.70 | 44 | 142975 | 33772 | 46509271 |
International normalised ratio increased | 21.92 | 9.70 | 72 | 142947 | 46811 | 46496232 |
Enthesopathy | 21.90 | 9.70 | 46 | 142973 | 4644 | 46538399 |
Clostridium difficile colitis | 21.86 | 9.70 | 15 | 143004 | 18538 | 46524505 |
Malignant melanoma | 21.78 | 9.70 | 75 | 142944 | 10159 | 46532884 |
Pruritus allergic | 21.60 | 9.70 | 21 | 142998 | 1030 | 46542013 |
Blood potassium increased | 21.53 | 9.70 | 106 | 142913 | 16861 | 46526182 |
Alopecia | 21.45 | 9.70 | 359 | 142660 | 162055 | 46380988 |
Poisoning | 21.44 | 9.70 | 8 | 143011 | 13986 | 46529057 |
Hepatocellular injury | 21.29 | 9.70 | 36 | 142983 | 29486 | 46513557 |
Joint prosthesis user | 21.27 | 9.70 | 7 | 143012 | 34 | 46543009 |
Radiculopathy | 21.11 | 9.70 | 47 | 142972 | 4938 | 46538105 |
Joint range of motion decreased | 21.01 | 9.70 | 97 | 142922 | 15027 | 46528016 |
Agitation | 20.81 | 9.70 | 93 | 142926 | 55322 | 46487721 |
Infective pulmonary exacerbation of cystic fibrosis | 20.66 | 9.70 | 4 | 143015 | 10803 | 46532240 |
Cardiac failure | 20.44 | 9.70 | 152 | 142867 | 79796 | 46463247 |
Breast cyst excision | 20.43 | 9.70 | 8 | 143011 | 69 | 46542974 |
Drug reaction with eosinophilia and systemic symptoms | 20.43 | 9.70 | 37 | 142982 | 29511 | 46513532 |
Ascites | 20.15 | 9.70 | 52 | 142967 | 36532 | 46506511 |
Hyperglycaemia | 19.98 | 9.70 | 49 | 142970 | 35022 | 46508021 |
Swelling | 19.93 | 9.70 | 511 | 142508 | 124000 | 46419043 |
Palmar-plantar erythrodysaesthesia syndrome | 19.82 | 9.70 | 20 | 142999 | 20431 | 46522612 |
Amblyopia | 19.80 | 9.70 | 11 | 143008 | 222 | 46542821 |
Joint effusion | 19.78 | 9.70 | 81 | 142938 | 11914 | 46531129 |
Tuberculin test positive | 19.64 | 9.70 | 34 | 142985 | 2970 | 46540073 |
Neutrophil count decreased | 19.41 | 9.70 | 68 | 142951 | 43358 | 46499685 |
COVID-19 | 19.37 | 9.70 | 17 | 143002 | 18558 | 46524485 |
Metabolic surgery | 19.22 | 9.70 | 19 | 143000 | 951 | 46542092 |
Bone erosion | 19.05 | 9.70 | 68 | 142951 | 9375 | 46533668 |
Limb injury | 19.03 | 9.70 | 112 | 142907 | 19062 | 46523981 |
Device issue | 18.84 | 9.70 | 20 | 142999 | 19960 | 46523083 |
Lower respiratory tract infection | 18.64 | 9.70 | 254 | 142765 | 54835 | 46488208 |
Diabetic ketoacidosis | 18.59 | 9.70 | 17 | 143002 | 18193 | 46524850 |
Acute hepatic failure | 18.58 | 9.70 | 11 | 143008 | 14710 | 46528333 |
Synovial cyst | 18.48 | 9.70 | 57 | 142962 | 7289 | 46535754 |
Sedation | 18.37 | 9.70 | 26 | 142993 | 22884 | 46520159 |
Gamma-glutamyltransferase increased | 18.35 | 9.70 | 44 | 142975 | 31696 | 46511347 |
Tuberculosis | 18.27 | 9.70 | 71 | 142948 | 10194 | 46532849 |
Body height decreased | 18.20 | 9.70 | 68 | 142951 | 9584 | 46533459 |
Injection related reaction | 18.07 | 9.70 | 14 | 143005 | 504 | 46542539 |
Lactic acidosis | 18.07 | 9.70 | 49 | 142970 | 33860 | 46509183 |
Drug resistance | 17.99 | 9.70 | 16 | 143003 | 17352 | 46525691 |
Lethargy | 17.97 | 9.70 | 88 | 142931 | 51083 | 46491960 |
Oral herpes | 17.81 | 9.70 | 111 | 142908 | 19279 | 46523764 |
Hyperbilirubinaemia | 17.70 | 9.70 | 5 | 143014 | 10433 | 46532610 |
Transplant rejection | 17.42 | 9.70 | 4 | 143015 | 9592 | 46533451 |
Gastrointestinal toxicity | 17.41 | 9.70 | 40 | 142979 | 4291 | 46538752 |
Hepatic failure | 17.28 | 9.70 | 49 | 142970 | 33367 | 46509676 |
Peritonitis bacterial | 16.97 | 9.70 | 3 | 143016 | 8650 | 46534393 |
Constipation | 16.91 | 9.70 | 405 | 142614 | 173692 | 46369351 |
Spondylitis | 16.33 | 9.70 | 25 | 142994 | 1970 | 46541073 |
Bronchitis | 16.10 | 9.70 | 432 | 142587 | 105547 | 46437496 |
Glomerulonephritis minimal lesion | 16.10 | 9.70 | 9 | 143010 | 184 | 46542859 |
Full blood count decreased | 16.09 | 9.70 | 27 | 142992 | 22184 | 46520859 |
Nodule | 16.04 | 9.70 | 92 | 142927 | 15513 | 46527530 |
Clostridium difficile infection | 15.99 | 9.70 | 33 | 142986 | 25070 | 46517973 |
Carpal tunnel syndrome | 15.98 | 9.70 | 93 | 142926 | 15766 | 46527277 |
Malignant polyp | 15.97 | 9.70 | 9 | 143010 | 187 | 46542856 |
Cardiogenic shock | 15.90 | 9.70 | 16 | 143003 | 16368 | 46526675 |
Finger deformity | 15.83 | 9.70 | 43 | 142976 | 5119 | 46537924 |
Tremor | 15.79 | 9.70 | 254 | 142765 | 115385 | 46427658 |
Myofascial pain syndrome | 15.62 | 9.70 | 24 | 142995 | 1897 | 46541146 |
Abortion induced | 15.50 | 9.70 | 6 | 143013 | 10254 | 46532789 |
Blood cholesterol increased | 15.43 | 9.70 | 189 | 142830 | 39824 | 46503219 |
Neoplasm progression | 15.42 | 9.70 | 37 | 142982 | 26646 | 46516397 |
Pleural effusion | 15.40 | 9.70 | 171 | 142848 | 82781 | 46460262 |
Oculomucocutaneous syndrome | 15.27 | 9.70 | 8 | 143011 | 143 | 46542900 |
Muscle spasticity | 15.23 | 9.70 | 8 | 143011 | 11432 | 46531611 |
Foetal death | 15.18 | 9.70 | 4 | 143015 | 8739 | 46534304 |
Chondropathy | 15.17 | 9.70 | 24 | 142995 | 1946 | 46541097 |
Product quality issue | 15.15 | 9.70 | 57 | 142962 | 35591 | 46507452 |
Abdominal pain upper | 15.15 | 9.70 | 566 | 142453 | 144739 | 46398304 |
Vitamin K deficiency | 15.02 | 9.70 | 12 | 143007 | 452 | 46542591 |
Progressive multifocal leukoencephalopathy | 15.01 | 9.70 | 8 | 143011 | 11338 | 46531705 |
Insomnia | 15.00 | 9.70 | 633 | 142386 | 164291 | 46378752 |
Hip surgery | 14.99 | 9.70 | 27 | 142992 | 2433 | 46540610 |
Respiratory distress | 14.93 | 9.70 | 49 | 142970 | 31867 | 46511176 |
Angina unstable | 14.93 | 9.70 | 54 | 142965 | 7494 | 46535549 |
Coma | 14.88 | 9.70 | 111 | 142908 | 58238 | 46484805 |
Emphysema | 14.82 | 9.70 | 61 | 142958 | 8993 | 46534050 |
Erythema multiforme | 14.81 | 9.70 | 64 | 142955 | 9640 | 46533403 |
Post procedural haemorrhage | 14.58 | 9.70 | 53 | 142966 | 7373 | 46535670 |
Fracture pain | 14.57 | 9.70 | 11 | 143008 | 381 | 46542662 |
Myelodysplastic syndrome | 14.51 | 9.70 | 16 | 143003 | 15695 | 46527348 |
Migraine | 14.50 | 9.70 | 298 | 142721 | 69728 | 46473315 |
Toe operation | 14.42 | 9.70 | 13 | 143006 | 579 | 46542464 |
Dressler's syndrome | 14.37 | 9.70 | 3 | 143016 | 0 | 46543043 |
Synovitis | 14.37 | 9.70 | 265 | 142754 | 60810 | 46482233 |
Gluten sensitivity | 14.19 | 9.70 | 12 | 143007 | 490 | 46542553 |
Lithotripsy | 14.19 | 9.70 | 4 | 143015 | 10 | 46543033 |
Caesarean section | 14.17 | 9.70 | 18 | 143001 | 16585 | 46526458 |
Spondylolisthesis | 14.15 | 9.70 | 30 | 142989 | 3048 | 46539995 |
Tubo-ovarian abscess | 14.15 | 9.70 | 10 | 143009 | 312 | 46542731 |
Neuralgia | 14.13 | 9.70 | 113 | 142906 | 21270 | 46521773 |
Blood parathyroid hormone decreased | 13.95 | 9.70 | 37 | 142982 | 4344 | 46538699 |
Immunoglobulins decreased | 13.93 | 9.70 | 15 | 143004 | 831 | 46542212 |
Back pain | 13.82 | 9.70 | 781 | 142238 | 209258 | 46333785 |
Therapeutic response decreased | 13.81 | 9.70 | 197 | 142822 | 42948 | 46500095 |
Cognitive disorder | 13.79 | 9.70 | 62 | 142957 | 36821 | 46506222 |
Pulmonary hypertension | 13.76 | 9.70 | 60 | 142959 | 35933 | 46507110 |
Walking aid user | 13.75 | 9.70 | 39 | 142980 | 4761 | 46538282 |
Nail injury | 13.69 | 9.70 | 11 | 143008 | 418 | 46542625 |
Orthostatic hypotension | 13.62 | 9.70 | 35 | 142984 | 24623 | 46518420 |
Ligament sprain | 13.55 | 9.70 | 66 | 142953 | 10453 | 46532590 |
Cell marker increased | 13.48 | 9.70 | 10 | 143009 | 337 | 46542706 |
Joint noise | 13.44 | 9.70 | 30 | 142989 | 3157 | 46539886 |
Surgery | 13.37 | 9.70 | 141 | 142878 | 28644 | 46514399 |
Pulmonary embolism | 13.37 | 9.70 | 243 | 142776 | 108342 | 46434701 |
Blood calcium decreased | 13.37 | 9.70 | 17 | 143002 | 15656 | 46527387 |
Psychotic disorder | 13.37 | 9.70 | 31 | 142988 | 22590 | 46520453 |
Posterior reversible encephalopathy syndrome | 13.36 | 9.70 | 16 | 143003 | 15125 | 46527918 |
Uterine perforation | 13.25 | 9.70 | 3 | 143016 | 7264 | 46535779 |
Drug tolerance | 13.25 | 9.70 | 30 | 142989 | 3188 | 46539855 |
Fear of injection | 13.18 | 9.70 | 35 | 142984 | 4112 | 46538931 |
Status epilepticus | 13.17 | 9.70 | 14 | 143005 | 13965 | 46529078 |
Blood bilirubin increased | 13.06 | 9.70 | 57 | 142962 | 34127 | 46508916 |
Cartilage injury | 13.06 | 9.70 | 20 | 142999 | 1577 | 46541466 |
Respiratory tract congestion | 12.96 | 9.70 | 75 | 142944 | 12689 | 46530354 |
Tongue cancer recurrent | 12.78 | 9.70 | 4 | 143015 | 16 | 46543027 |
Meningitis streptococcal | 12.61 | 9.70 | 7 | 143012 | 141 | 46542902 |
Bronchomalacia | 12.61 | 9.70 | 7 | 143012 | 141 | 46542902 |
Haemodynamic instability | 12.56 | 9.70 | 4 | 143015 | 7721 | 46535322 |
Adrenal suppression | 12.50 | 9.70 | 15 | 143004 | 936 | 46542107 |
Circulatory collapse | 12.48 | 9.70 | 30 | 142989 | 21594 | 46521449 |
Eosinophilia | 12.46 | 9.70 | 25 | 142994 | 19192 | 46523851 |
Electrolyte imbalance | 12.42 | 9.70 | 21 | 142998 | 17205 | 46525838 |
Stenosis | 12.33 | 9.70 | 14 | 143005 | 823 | 46542220 |
Neuroma | 12.31 | 9.70 | 10 | 143009 | 386 | 46542657 |
Neuroprosthesis implantation | 12.30 | 9.70 | 3 | 143016 | 3 | 46543040 |
Inflammation | 12.30 | 9.70 | 214 | 142805 | 48567 | 46494476 |
Spinal deformity | 12.29 | 9.70 | 15 | 143004 | 952 | 46542091 |
Periarticular disorder | 12.21 | 9.70 | 5 | 143014 | 49 | 46542994 |
Pulmonary oedema | 12.20 | 9.70 | 99 | 142920 | 51006 | 46492037 |
Lymphocyte count decreased | 12.17 | 9.70 | 39 | 142980 | 25550 | 46517493 |
Rheumatoid factor positive | 12.12 | 9.70 | 28 | 142991 | 20433 | 46522610 |
Dystonia | 12.11 | 9.70 | 10 | 143009 | 11247 | 46531796 |
Flushing | 12.07 | 9.70 | 133 | 142886 | 64481 | 46478562 |
Eye disorder | 12.06 | 9.70 | 96 | 142923 | 18045 | 46524998 |
Wrist fracture | 11.94 | 9.70 | 68 | 142951 | 11435 | 46531608 |
Haemorrhage subcutaneous | 11.86 | 9.70 | 27 | 142992 | 2879 | 46540164 |
Tenosynovitis | 11.80 | 9.70 | 50 | 142969 | 7465 | 46535578 |
Suicidal ideation | 11.79 | 9.70 | 113 | 142906 | 56269 | 46486774 |
Small intestine ulcer | 11.79 | 9.70 | 9 | 143010 | 317 | 46542726 |
Generalised tonic-clonic seizure | 11.77 | 9.70 | 43 | 142976 | 27079 | 46515964 |
Transfusion | 11.65 | 9.70 | 14 | 143005 | 13217 | 46529826 |
Vertebral foraminal stenosis | 11.64 | 9.70 | 14 | 143005 | 875 | 46542168 |
Miosis | 11.64 | 9.70 | 3 | 143016 | 6654 | 46536389 |
Gastric perforation | 11.64 | 9.70 | 17 | 143002 | 1285 | 46541758 |
Accidental exposure to product | 11.58 | 9.70 | 30 | 142989 | 21051 | 46521992 |
Joint dislocation | 11.53 | 9.70 | 66 | 142953 | 11120 | 46531923 |
Device related infection | 11.52 | 9.70 | 30 | 142989 | 21011 | 46522032 |
Acute respiratory failure | 11.49 | 9.70 | 48 | 142971 | 29090 | 46513953 |
Spinal cord injury cervical | 11.46 | 9.70 | 4 | 143015 | 24 | 46543019 |
Genital haemorrhage | 11.41 | 9.70 | 3 | 143016 | 6563 | 46536480 |
Underdose | 11.40 | 9.70 | 27 | 142992 | 19531 | 46523512 |
Coronary artery surgery | 11.39 | 9.70 | 5 | 143014 | 59 | 46542984 |
Pulmonary congestion | 11.35 | 9.70 | 81 | 142938 | 14718 | 46528325 |
Synovial rupture | 11.34 | 9.70 | 7 | 143012 | 173 | 46542870 |
Coronary artery stenosis | 11.33 | 9.70 | 36 | 142983 | 4677 | 46538366 |
Live birth | 11.33 | 9.70 | 9 | 143010 | 10321 | 46532722 |
Disease risk factor | 11.32 | 9.70 | 5 | 143014 | 60 | 46542983 |
Psoriasis | 11.25 | 9.70 | 318 | 142701 | 78286 | 46464757 |
Parotid gland enlargement | 11.22 | 9.70 | 13 | 143006 | 781 | 46542262 |
Brain oedema | 11.21 | 9.70 | 13 | 143006 | 12465 | 46530578 |
Axial spondyloarthritis | 11.17 | 9.70 | 6 | 143013 | 113 | 46542930 |
Perseveration | 11.17 | 9.70 | 8 | 143011 | 255 | 46542788 |
Urinary tract pain | 11.16 | 9.70 | 7 | 143012 | 178 | 46542865 |
Presyncope | 11.13 | 9.70 | 38 | 142981 | 24416 | 46518627 |
Groin pain | 11.05 | 9.70 | 56 | 142963 | 9009 | 46534034 |
Renal tubular necrosis | 11.03 | 9.70 | 10 | 143009 | 10749 | 46532294 |
Rhabdomyolysis | 11.03 | 9.70 | 79 | 142940 | 41830 | 46501213 |
Drug interaction | 11.02 | 9.70 | 509 | 142510 | 202585 | 46340458 |
Hallucination, visual | 10.96 | 9.70 | 24 | 142995 | 17849 | 46525194 |
Tendon rupture | 10.95 | 9.70 | 50 | 142969 | 7709 | 46535334 |
Hepatic encephalopathy | 10.95 | 9.70 | 9 | 143010 | 10148 | 46532895 |
Medication error | 10.94 | 9.70 | 53 | 142966 | 30858 | 46512185 |
Back injury | 10.83 | 9.70 | 46 | 142973 | 6875 | 46536168 |
Urinary tract infection | 10.79 | 9.70 | 558 | 142461 | 219708 | 46323335 |
General physical health deterioration | 10.77 | 9.70 | 271 | 142748 | 115498 | 46427545 |
Granuloma skin | 10.74 | 9.70 | 29 | 142990 | 3441 | 46539602 |
Femur fracture | 10.70 | 9.70 | 166 | 142853 | 36831 | 46506212 |
Mass excision | 10.70 | 9.70 | 8 | 143011 | 273 | 46542770 |
Prescription drug used without a prescription | 10.68 | 9.70 | 17 | 143002 | 1385 | 46541658 |
Dyspepsia | 10.65 | 9.70 | 280 | 142739 | 68192 | 46474851 |
Panniculitis | 10.60 | 9.70 | 40 | 142979 | 5664 | 46537379 |
Wrong technique in product usage process | 10.58 | 9.70 | 111 | 142908 | 54311 | 46488732 |
Respiratory depression | 10.51 | 9.70 | 12 | 143007 | 11588 | 46531455 |
Weight fluctuation | 10.49 | 9.70 | 44 | 142975 | 6540 | 46536503 |
Interferon gamma release assay positive | 10.47 | 9.70 | 4 | 143015 | 32 | 46543011 |
Unevaluable event | 10.32 | 9.70 | 91 | 142928 | 46084 | 46496959 |
Necrotising fasciitis | 10.30 | 9.70 | 24 | 142995 | 2599 | 46540444 |
Tendonitis | 10.29 | 9.70 | 77 | 142942 | 14200 | 46528843 |
Ejection fraction decreased | 10.26 | 9.70 | 25 | 142994 | 17912 | 46525131 |
Cervical spinal stenosis | 10.25 | 9.70 | 20 | 142999 | 1915 | 46541128 |
Knee operation | 10.20 | 9.70 | 35 | 142984 | 4731 | 46538312 |
Coeliac artery compression syndrome | 10.18 | 9.70 | 6 | 143013 | 136 | 46542907 |
Wound | 10.18 | 9.70 | 83 | 142936 | 42719 | 46500324 |
Anuria | 10.17 | 9.70 | 12 | 143007 | 11419 | 46531624 |
Pneumonia aspiration | 10.17 | 9.70 | 56 | 142963 | 31549 | 46511494 |
Inflammatory bowel disease | 10.13 | 9.70 | 27 | 142992 | 3178 | 46539865 |
Compression fracture | 10.12 | 9.70 | 42 | 142977 | 6215 | 46536828 |
Pathogen resistance | 10.10 | 9.70 | 3 | 143016 | 6057 | 46536986 |
Mania | 10.07 | 9.70 | 11 | 143008 | 10835 | 46532208 |
Road traffic accident | 10.06 | 9.70 | 114 | 142905 | 23577 | 46519466 |
Laryngeal papilloma | 10.01 | 9.70 | 3 | 143016 | 10 | 46543033 |
Respiratory papilloma | 10.01 | 9.70 | 3 | 143016 | 10 | 46543033 |
Dyskinesia | 10.00 | 9.70 | 50 | 142969 | 28875 | 46514168 |
Purpura senile | 10.00 | 9.70 | 11 | 143008 | 624 | 46542419 |
Accidental overdose | 9.95 | 9.70 | 30 | 142989 | 20036 | 46523007 |
Metastases to liver | 9.92 | 9.70 | 29 | 142990 | 19556 | 46523487 |
Cutaneous symptom | 9.91 | 9.70 | 6 | 143013 | 143 | 46542900 |
Aggression | 9.91 | 9.70 | 36 | 142983 | 22708 | 46520335 |
Patellofemoral pain syndrome | 9.90 | 9.70 | 10 | 143009 | 514 | 46542529 |
Medulloblastoma | 9.88 | 9.70 | 4 | 143015 | 38 | 46543005 |
Oesophageal spasm | 9.87 | 9.70 | 20 | 142999 | 1969 | 46541074 |
Tooth infection | 9.86 | 9.70 | 68 | 142951 | 12218 | 46530825 |
Limb discomfort | 9.86 | 9.70 | 110 | 142909 | 22666 | 46520377 |
Blood pressure systolic increased | 9.84 | 9.70 | 133 | 142886 | 28654 | 46514389 |
Gastritis | 9.84 | 9.70 | 154 | 142865 | 34224 | 46508819 |
No adverse event | 9.77 | 9.70 | 63 | 142956 | 34168 | 46508875 |
Breast cyst | 9.76 | 9.70 | 17 | 143002 | 1492 | 46541551 |
Asthma | 9.71 | 9.70 | 210 | 142809 | 91332 | 46451711 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug hypersensitivity | 312.77 | 10.33 | 484 | 51899 | 68035 | 29832060 |
Ankylosing spondylitis | 230.54 | 10.33 | 126 | 52257 | 4408 | 29895687 |
Psoriatic arthropathy | 149.12 | 10.33 | 160 | 52223 | 15601 | 29884494 |
Arthralgia | 147.80 | 10.33 | 547 | 51836 | 135244 | 29764851 |
Death | 135.52 | 10.33 | 263 | 52120 | 357020 | 29543075 |
Toxicity to various agents | 129.00 | 10.33 | 75 | 52308 | 177108 | 29722987 |
Rheumatoid arthritis | 123.53 | 10.33 | 242 | 52141 | 40955 | 29859140 |
Arthritis | 116.22 | 10.33 | 176 | 52207 | 24225 | 29875870 |
Pain | 114.83 | 10.33 | 600 | 51783 | 172041 | 29728054 |
Osteoarthritis | 94.04 | 10.33 | 137 | 52246 | 18212 | 29881883 |
Drug abuse | 84.26 | 10.33 | 20 | 52363 | 82052 | 29818043 |
Myocardial infarction | 82.97 | 10.33 | 436 | 51947 | 125189 | 29774906 |
Back pain | 73.95 | 10.33 | 365 | 52018 | 102231 | 29797864 |
Completed suicide | 65.64 | 10.33 | 47 | 52336 | 99445 | 29800650 |
Arthropathy | 64.83 | 10.33 | 124 | 52259 | 20603 | 29879492 |
Therapeutic product effect incomplete | 57.43 | 10.33 | 159 | 52224 | 33675 | 29866420 |
Neck pain | 55.57 | 10.33 | 117 | 52266 | 20827 | 29879268 |
Knee arthroplasty | 52.96 | 10.33 | 57 | 52326 | 5573 | 29894522 |
Febrile neutropenia | 50.09 | 10.33 | 68 | 52315 | 106625 | 29793470 |
Acute kidney injury | 49.55 | 10.33 | 279 | 52104 | 273563 | 29626532 |
Drug ineffective | 48.68 | 10.33 | 850 | 51533 | 339537 | 29560558 |
Joint swelling | 46.68 | 10.33 | 184 | 52199 | 46762 | 29853333 |
Drug interaction | 44.96 | 10.33 | 188 | 52195 | 199380 | 29700715 |
Intervertebral disc protrusion | 44.30 | 10.33 | 67 | 52316 | 9204 | 29890891 |
Musculoskeletal stiffness | 43.54 | 10.33 | 150 | 52233 | 35731 | 29864364 |
Coronary artery disease | 39.49 | 10.33 | 182 | 52201 | 49530 | 29850565 |
Hypotension | 39.19 | 10.33 | 199 | 52184 | 200366 | 29699729 |
Muscle swelling | 39.00 | 10.33 | 17 | 52366 | 358 | 29899737 |
Thrombocytopenia | 37.49 | 10.33 | 119 | 52264 | 136925 | 29763170 |
Ependymoma | 37.29 | 10.33 | 11 | 52372 | 68 | 29900027 |
Psoriasis | 37.06 | 10.33 | 160 | 52223 | 42346 | 29857749 |
Off label use | 36.87 | 10.33 | 270 | 52113 | 249020 | 29651075 |
Exostosis | 36.10 | 10.33 | 37 | 52346 | 3418 | 29896677 |
General physical health deterioration | 35.59 | 10.33 | 76 | 52307 | 99868 | 29800227 |
Sacroiliitis | 33.26 | 10.33 | 20 | 52363 | 840 | 29899255 |
Fibromyalgia | 32.88 | 10.33 | 31 | 52352 | 2587 | 29897508 |
Cardio-respiratory arrest | 31.73 | 10.33 | 32 | 52351 | 57274 | 29842821 |
Sepsis | 31.04 | 10.33 | 141 | 52242 | 146254 | 29753841 |
Cerebral artery thrombosis | 30.76 | 10.33 | 16 | 52367 | 505 | 29899590 |
Pain in extremity | 30.18 | 10.33 | 310 | 52073 | 109911 | 29790184 |
Brain scan abnormal | 30.05 | 10.33 | 17 | 52366 | 636 | 29899459 |
Lactic acidosis | 29.38 | 10.33 | 9 | 52374 | 31204 | 29868891 |
Axial spondyloarthritis | 29.15 | 10.33 | 11 | 52372 | 157 | 29899938 |
Therapeutic product effect decreased | 28.92 | 10.33 | 114 | 52269 | 28962 | 29871133 |
Transposition of the great vessels | 28.74 | 10.33 | 15 | 52368 | 477 | 29899618 |
Interstitial lung disease | 28.72 | 10.33 | 192 | 52191 | 60005 | 29840090 |
Coronary artery stenosis | 28.03 | 10.33 | 54 | 52329 | 9016 | 29891079 |
Hypoglycaemia | 27.62 | 10.33 | 29 | 52354 | 50952 | 29849143 |
Anxiety | 27.14 | 10.33 | 258 | 52125 | 89613 | 29810482 |
Neutropenia | 27.13 | 10.33 | 124 | 52259 | 128416 | 29771679 |
Synovitis | 26.35 | 10.33 | 55 | 52328 | 9728 | 29890367 |
Multiple organ dysfunction syndrome | 26.35 | 10.33 | 44 | 52339 | 63443 | 29836652 |
Joint range of motion decreased | 26.18 | 10.33 | 41 | 52342 | 5804 | 29894291 |
Pancytopenia | 26.04 | 10.33 | 70 | 52313 | 84982 | 29815113 |
Cytomegalovirus infection | 25.85 | 10.33 | 5 | 52378 | 23669 | 29876426 |
Intentional overdose | 25.54 | 10.33 | 21 | 52362 | 41460 | 29858635 |
Overdose | 25.38 | 10.33 | 70 | 52313 | 84267 | 29815828 |
Hypoaesthesia | 25.29 | 10.33 | 172 | 52211 | 54058 | 29846037 |
Blood cholesterol increased | 25.16 | 10.33 | 76 | 52307 | 16894 | 29883201 |
Intervertebral disc degeneration | 25.16 | 10.33 | 38 | 52345 | 5213 | 29894882 |
Plasma cell myeloma | 25.14 | 10.33 | 34 | 52349 | 53428 | 29846667 |
Hernia | 24.77 | 10.33 | 50 | 52333 | 8636 | 29891459 |
Loss of personal independence in daily activities | 24.37 | 10.33 | 88 | 52295 | 21447 | 29878648 |
Emotional distress | 23.75 | 10.33 | 71 | 52312 | 15694 | 29884401 |
Gastric ulcer haemorrhage | 23.42 | 10.33 | 37 | 52346 | 5277 | 29894818 |
Leukopenia | 23.23 | 10.33 | 39 | 52344 | 56120 | 29843975 |
Foetal exposure during pregnancy | 22.29 | 10.33 | 19 | 52364 | 36852 | 29863243 |
Grip strength decreased | 22.26 | 10.33 | 23 | 52360 | 2145 | 29897950 |
Blood pressure increased | 21.96 | 10.33 | 207 | 52176 | 71721 | 29828374 |
Blood pressure fluctuation | 21.95 | 10.33 | 74 | 52309 | 17429 | 29882666 |
Epstein-Barr virus infection reactivation | 21.74 | 10.33 | 10 | 52373 | 240 | 29899855 |
Xyphoid retraction | 21.69 | 10.33 | 9 | 52374 | 167 | 29899928 |
Arachnoiditis | 21.60 | 10.33 | 11 | 52372 | 332 | 29899763 |
Coronary artery occlusion | 21.52 | 10.33 | 55 | 52328 | 11102 | 29888993 |
Osteopenia | 21.37 | 10.33 | 33 | 52350 | 4615 | 29895480 |
Hyperkalaemia | 21.22 | 10.33 | 53 | 52330 | 65957 | 29834138 |
Nasopharyngitis | 20.87 | 10.33 | 175 | 52208 | 58674 | 29841421 |
Drug resistance | 20.46 | 10.33 | 5 | 52378 | 20128 | 29879967 |
Victim of child abuse | 20.32 | 10.33 | 10 | 52373 | 280 | 29899815 |
Spinal stenosis | 20.28 | 10.33 | 31 | 52352 | 4298 | 29895797 |
Mass | 20.24 | 10.33 | 41 | 52342 | 7099 | 29892996 |
Rotator cuff syndrome | 20.24 | 10.33 | 35 | 52348 | 5378 | 29894717 |
Chest expansion decreased | 19.76 | 10.33 | 8 | 52375 | 139 | 29899956 |
Hypokalaemia | 19.72 | 10.33 | 36 | 52347 | 50156 | 29849939 |
Diarrhoea | 19.42 | 10.33 | 441 | 51942 | 333662 | 29566433 |
Benign abdominal neoplasm | 19.28 | 10.33 | 7 | 52376 | 89 | 29900006 |
Carpal tunnel syndrome | 19.12 | 10.33 | 30 | 52353 | 4253 | 29895842 |
Abdominal discomfort | 18.87 | 10.33 | 148 | 52235 | 48643 | 29851452 |
Fracture | 18.85 | 10.33 | 36 | 52347 | 5970 | 29894125 |
Road traffic accident | 18.68 | 10.33 | 69 | 52314 | 17002 | 29883093 |
Bradycardia | 18.53 | 10.33 | 56 | 52327 | 65470 | 29834625 |
Inflammation | 18.49 | 10.33 | 82 | 52301 | 21944 | 29878151 |
Hyperhidrosis | 18.49 | 10.33 | 189 | 52194 | 66901 | 29833194 |
Joint space narrowing | 18.38 | 10.33 | 6 | 52377 | 54 | 29900041 |
Depression | 18.31 | 10.33 | 240 | 52143 | 90197 | 29809898 |
Heart rate decreased | 18.27 | 10.33 | 79 | 52304 | 20915 | 29879180 |
Chest pain | 18.24 | 10.33 | 298 | 52085 | 117329 | 29782766 |
Cardiac arrest | 18.16 | 10.33 | 92 | 52291 | 92758 | 29807337 |
Gastric ulcer | 18.15 | 10.33 | 63 | 52320 | 15058 | 29885037 |
Angina unstable | 18.13 | 10.33 | 55 | 52328 | 12255 | 29887840 |
Foot deformity | 18.09 | 10.33 | 26 | 52357 | 3411 | 29896684 |
Investigation abnormal | 18.03 | 10.33 | 10 | 52373 | 360 | 29899735 |
Hip arthroplasty | 17.83 | 10.33 | 27 | 52356 | 3713 | 29896382 |
Energy increased | 17.75 | 10.33 | 16 | 52367 | 1260 | 29898835 |
Agitation | 17.70 | 10.33 | 43 | 52340 | 54030 | 29846065 |
Peptic ulcer | 17.69 | 10.33 | 23 | 52360 | 2745 | 29897350 |
Transient ischaemic attack | 17.64 | 10.33 | 89 | 52294 | 25111 | 29874984 |
Musculoskeletal pain | 17.44 | 10.33 | 103 | 52280 | 30837 | 29869258 |
Premature baby | 17.25 | 10.33 | 4 | 52379 | 16687 | 29883408 |
Intervertebral disc disorder | 16.95 | 10.33 | 18 | 52365 | 1733 | 29898362 |
Hepatic calcification | 16.94 | 10.33 | 5 | 52378 | 31 | 29900064 |
Septic shock | 16.83 | 10.33 | 56 | 52327 | 63551 | 29836544 |
Knee operation | 16.82 | 10.33 | 16 | 52367 | 1350 | 29898745 |
Coma | 16.81 | 10.33 | 28 | 52355 | 40421 | 29859674 |
Nervousness | 16.74 | 10.33 | 52 | 52331 | 11736 | 29888359 |
Impaired work ability | 16.71 | 10.33 | 33 | 52350 | 5610 | 29894485 |
Cerebrovascular accident | 16.68 | 10.33 | 221 | 52162 | 83256 | 29816839 |
Oesophageal infection | 16.26 | 10.33 | 8 | 52375 | 224 | 29899871 |
Gait disturbance | 16.22 | 10.33 | 201 | 52182 | 74576 | 29825519 |
Small intestine ulcer | 16.19 | 10.33 | 10 | 52373 | 441 | 29899654 |
Drug dependence | 16.19 | 10.33 | 77 | 52306 | 21218 | 29878877 |
Spinal osteoarthritis | 16.11 | 10.33 | 35 | 52348 | 6364 | 29893731 |
Gastrooesophageal reflux disease | 16.05 | 10.33 | 104 | 52279 | 32151 | 29867944 |
Scoliosis | 16.02 | 10.33 | 17 | 52366 | 1635 | 29898460 |
Lumbar spinal stenosis | 15.87 | 10.33 | 21 | 52362 | 2549 | 29897546 |
Electrocardiogram QT prolonged | 15.65 | 10.33 | 24 | 52359 | 35811 | 29864284 |
Suicide attempt | 15.62 | 10.33 | 25 | 52358 | 36672 | 29863423 |
Platelet count decreased | 15.60 | 10.33 | 115 | 52268 | 106014 | 29794081 |
Arteriosclerosis | 15.58 | 10.33 | 48 | 52335 | 10785 | 29889310 |
Spinal disorder | 15.52 | 10.33 | 24 | 52359 | 3361 | 29896734 |
Ankle fracture | 15.51 | 10.33 | 25 | 52358 | 3626 | 29896469 |
Drug tolerance | 15.46 | 10.33 | 19 | 52364 | 2143 | 29897952 |
Hepatic cirrhosis | 15.32 | 10.33 | 62 | 52321 | 15937 | 29884158 |
Seizure | 15.31 | 10.33 | 105 | 52278 | 98370 | 29801725 |
Hypomagnesaemia | 15.24 | 10.33 | 5 | 52378 | 16593 | 29883502 |
Joint injury | 15.10 | 10.33 | 35 | 52348 | 6642 | 29893453 |
Anaemia | 14.91 | 10.33 | 265 | 52118 | 207727 | 29692368 |
Mucosal inflammation | 14.73 | 10.33 | 19 | 52364 | 30475 | 29869620 |
Injury | 14.69 | 10.33 | 76 | 52307 | 21655 | 29878440 |
Diverticulitis | 14.68 | 10.33 | 65 | 52318 | 17380 | 29882715 |
Gastrointestinal haemorrhage | 14.68 | 10.33 | 216 | 52167 | 83230 | 29816865 |
Orchitis noninfective | 14.62 | 10.33 | 4 | 52379 | 18 | 29900077 |
Confusional state | 14.60 | 10.33 | 158 | 52225 | 134676 | 29765419 |
Periarthritis | 14.53 | 10.33 | 13 | 52370 | 1014 | 29899081 |
Spinal compression fracture | 14.46 | 10.33 | 33 | 52350 | 6201 | 29893894 |
Brain neoplasm malignant | 14.36 | 10.33 | 10 | 52373 | 541 | 29899554 |
Rhabdomyolysis | 14.20 | 10.33 | 60 | 52323 | 63520 | 29836575 |
Myoclonus | 14.14 | 10.33 | 3 | 52380 | 13309 | 29886786 |
Hyperbilirubinaemia | 14.05 | 10.33 | 6 | 52377 | 16936 | 29883159 |
Blood creatinine increased | 13.92 | 10.33 | 98 | 52285 | 91277 | 29808818 |
Iritis | 13.71 | 10.33 | 14 | 52369 | 1288 | 29898807 |
Child abuse | 13.66 | 10.33 | 7 | 52376 | 214 | 29899881 |
Renal failure | 13.61 | 10.33 | 152 | 52231 | 128814 | 29771281 |
Facet joint syndrome | 13.57 | 10.33 | 7 | 52376 | 217 | 29899878 |
Inadequate analgesia | 13.55 | 10.33 | 20 | 52363 | 2688 | 29897407 |
Medulloblastoma | 13.53 | 10.33 | 5 | 52378 | 67 | 29900028 |
Myalgia intercostal | 13.52 | 10.33 | 4 | 52379 | 25 | 29900070 |
Hypoxia | 13.45 | 10.33 | 41 | 52342 | 47813 | 29852282 |
Intermittent claudication | 13.41 | 10.33 | 18 | 52365 | 2216 | 29897879 |
Drug withdrawal syndrome | 13.20 | 10.33 | 69 | 52314 | 19740 | 29880355 |
Gingival ulceration | 13.18 | 10.33 | 8 | 52375 | 342 | 29899753 |
Neuroleptic malignant syndrome | 13.15 | 10.33 | 6 | 52377 | 16289 | 29883806 |
Mobility decreased | 13.04 | 10.33 | 84 | 52299 | 25915 | 29874180 |
Nerve compression | 13.03 | 10.33 | 20 | 52363 | 2782 | 29897313 |
Rebound psychosis | 13.00 | 10.33 | 6 | 52377 | 145 | 29899950 |
Metabolic acidosis | 12.89 | 10.33 | 29 | 52354 | 37432 | 29862663 |
Myofascial pain syndrome | 12.85 | 10.33 | 8 | 52375 | 358 | 29899737 |
Amoebic dysentery | 12.78 | 10.33 | 4 | 52379 | 31 | 29900064 |
Hepatitis chronic persistent | 12.77 | 10.33 | 3 | 52380 | 6 | 29900089 |
Pulmonary tuberculosis | 12.72 | 10.33 | 27 | 52356 | 4830 | 29895265 |
Fluid overload | 12.60 | 10.33 | 9 | 52374 | 19083 | 29881012 |
Osteomyelitis | 12.58 | 10.33 | 55 | 52328 | 14626 | 29885469 |
Duodenal ulcer | 12.54 | 10.33 | 42 | 52341 | 9859 | 29890236 |
Mitral valve incompetence | 12.45 | 10.33 | 51 | 52332 | 13183 | 29886912 |
Agranulocytosis | 12.43 | 10.33 | 12 | 52371 | 21930 | 29878165 |
Cardiogenic shock | 12.43 | 10.33 | 7 | 52376 | 16854 | 29883241 |
Aggression | 12.36 | 10.33 | 29 | 52354 | 36878 | 29863217 |
Hypercholesterolaemia | 12.21 | 10.33 | 35 | 52348 | 7557 | 29892538 |
Drug abuser | 12.15 | 10.33 | 25 | 52358 | 4376 | 29895719 |
Stab wound | 12.06 | 10.33 | 6 | 52377 | 172 | 29899923 |
Back disorder | 12.03 | 10.33 | 30 | 52353 | 5964 | 29894131 |
Sciatica | 11.97 | 10.33 | 27 | 52356 | 5034 | 29895061 |
Generalised tonic-clonic seizure | 11.90 | 10.33 | 10 | 52373 | 19541 | 29880554 |
Dyspepsia | 11.72 | 10.33 | 92 | 52291 | 30237 | 29869858 |
Haematochezia | 11.72 | 10.33 | 101 | 52282 | 34121 | 29865974 |
Herpes zoster | 11.67 | 10.33 | 91 | 52292 | 29852 | 29870243 |
Drug level increased | 11.66 | 10.33 | 9 | 52374 | 18345 | 29881750 |
Pyrexia | 11.63 | 10.33 | 410 | 51973 | 294079 | 29606016 |
Drug reaction with eosinophilia and systemic symptoms | 11.58 | 10.33 | 20 | 52363 | 28468 | 29871627 |
Inflammatory bowel disease | 11.57 | 10.33 | 17 | 52366 | 2276 | 29897819 |
Hyperglycaemia | 11.51 | 10.33 | 28 | 52355 | 35172 | 29864923 |
Blood bilirubin increased | 11.32 | 10.33 | 30 | 52353 | 36606 | 29863489 |
Chronic idiopathic pain syndrome | 11.24 | 10.33 | 3 | 52380 | 12 | 29900083 |
Erythema multiforme | 11.13 | 10.33 | 35 | 52348 | 7950 | 29892145 |
Hyperlipidaemia | 11.09 | 10.33 | 51 | 52332 | 13856 | 29886239 |
Cardiac failure | 11.04 | 10.33 | 93 | 52290 | 83325 | 29816770 |
Adhesion | 11.03 | 10.33 | 9 | 52374 | 619 | 29899476 |
Therapy non-responder | 10.80 | 10.33 | 22 | 52361 | 29431 | 29870664 |
Status epilepticus | 10.77 | 10.33 | 3 | 52380 | 11069 | 29889026 |
Application site rash | 10.76 | 10.33 | 10 | 52373 | 819 | 29899276 |
Oesophagogastric fundoplasty | 10.70 | 10.33 | 3 | 52380 | 15 | 29900080 |
Ascites | 10.66 | 10.33 | 30 | 52353 | 35891 | 29864204 |
Skin irritation | 10.63 | 10.33 | 23 | 52360 | 4169 | 29895926 |
Inflammatory pain | 10.60 | 10.33 | 4 | 52379 | 57 | 29900038 |
Prostate cancer | 10.58 | 10.33 | 75 | 52308 | 23882 | 29876213 |
Retro-orbital neoplasm | 10.54 | 10.33 | 3 | 52380 | 16 | 29900079 |
Atypical teratoid/rhabdoid tumour of CNS | 10.54 | 10.33 | 3 | 52380 | 16 | 29900079 |
Ankle operation | 10.43 | 10.33 | 6 | 52377 | 232 | 29899863 |
Cyst | 10.42 | 10.33 | 22 | 52361 | 3921 | 29896174 |
Source | Code | Description |
---|---|---|
ATC | C08CA51 | CARDIOVASCULAR SYSTEM CALCIUM CHANNEL BLOCKERS SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS Dihydropyridine derivatives |
ATC | L01XX33 | ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS ANTINEOPLASTIC AGENTS OTHER ANTINEOPLASTIC AGENTS Other antineoplastic agents |
ATC | M01AH01 | MUSCULO-SKELETAL SYSTEM ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS Coxibs |
FDA CS | M0001335 | Anti-Inflammatory Agents, Non-Steroidal |
FDA MoA | N0000000160 | Cyclooxygenase Inhibitors |
FDA EPC | N0000175722 | Nonsteroidal Anti-inflammatory Drug |
MeSH PA | D000700 | Analgesics |
MeSH PA | D018712 | Analgesics, Non-Narcotic |
MeSH PA | D000893 | Anti-Inflammatory Agents |
MeSH PA | D000894 | Anti-Inflammatory Agents, Non-Steroidal |
MeSH PA | D018501 | Antirheumatic Agents |
MeSH PA | D052246 | Cyclooxygenase 2 Inhibitors |
MeSH PA | D016861 | Cyclooxygenase Inhibitors |
MeSH PA | D004791 | Enzyme Inhibitors |
MeSH PA | D018373 | Peripheral Nervous System Agents |
MeSH PA | D018689 | Sensory System Agents |
CHEBI has role | CHEBI:50629 | cyclooxygenase-2 inhibitor |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Ankylosing spondylitis | indication | 9631008 | DOID:7147 |
Rheumatoid arthritis | indication | 69896004 | DOID:7148 |
Dysmenorrhea | indication | 266599000 | |
Osteoarthritis | indication | 396275006 | |
Juvenile rheumatoid arthritis | indication | 410795001 | |
Acute postoperative pain | indication | 107401000119105 | |
Alcoholism | contraindication | 7200002 | |
Peptic ulcer | contraindication | 13200003 | DOID:750 |
Myocardial infarction | contraindication | 22298006 | DOID:5844 |
Dehydration | contraindication | 34095006 | |
Hypertensive disorder | contraindication | 38341003 | DOID:10763 |
Gastrointestinal ulcer | contraindication | 40845000 | |
Body fluid retention | contraindication | 43498006 | |
Chronic heart failure | contraindication | 48447003 | |
Disorder of cardiovascular system | contraindication | 49601007 | DOID:1287 |
Gastrointestinal perforation | contraindication | 51875005 | |
Acute nephropathy | contraindication | 58574008 | |
Gastrointestinal hemorrhage | contraindication | 74474003 | |
Kidney disease | contraindication | 90708001 | DOID:557 |
Liver function tests abnormal | contraindication | 166603001 | |
Asthma | contraindication | 195967001 | DOID:2841 |
Cerebrovascular accident | contraindication | 230690007 | |
Coronary artery bypass graft | contraindication | 232717009 | |
Disease of liver | contraindication | 235856003 | DOID:409 |
Edema | contraindication | 267038008 | |
Anemia | contraindication | 271737000 | DOID:2355 |
Pregnancy, function | contraindication | 289908002 | |
Thromboembolic disorder | contraindication | 371039008 | |
Cardiovascular event risk | contraindication | 395112001 | |
Smokes tobacco daily | contraindication | 449868002 |
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 9.79 | acidic |
None
Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Exclusivity date | Description |
---|---|---|---|---|---|---|---|---|---|
EQ 10MG BASE;200MG | CONSENSI | COEPTIS | N210045 | May 31, 2018 | RX | TABLET | ORAL | May 31, 2021 | NEW COMBINULLTION |
EQ 2.5MG BASE;200MG | CONSENSI | COEPTIS | N210045 | May 31, 2018 | RX | TABLET | ORAL | May 31, 2021 | NEW COMBINULLTION |
EQ 5MG BASE;200MG | CONSENSI | COEPTIS | N210045 | May 31, 2018 | RX | TABLET | ORAL | May 31, 2021 | NEW COMBINULLTION |
25MG/ML | ELYXYB | DR REDDYS | N212157 | May 5, 2020 | DISCN | SOLUTION | ORAL | May 5, 2023 | NEW PRODUCT |
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase 2 | Enzyme | INHIBITOR | IC50 | 7.24 | WOMBAT-PK | CHEMBL | |||
Sodium-dependent serotonin transporter | Transporter | Ki | 5.48 | DRUG MATRIX | |||||
Sodium-dependent noradrenaline transporter | Transporter | Ki | 5.14 | DRUG MATRIX | |||||
Alpha-2B adrenergic receptor | GPCR | Ki | 6.16 | DRUG MATRIX | |||||
Beta-3 adrenergic receptor | GPCR | Ki | 4.92 | DRUG MATRIX | |||||
Cytochrome P450 2D6 | Enzyme | IC50 | 6 | DRUG MATRIX | |||||
Adenosine receptor A3 | GPCR | Ki | 4.86 | DRUG MATRIX | |||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Enzyme | IC50 | 5.03 | DRUG MATRIX | |||||
Carbonic anhydrase 2 | Enzyme | IC50 | 7.68 | WOMBAT-PK | |||||
Sodium-dependent dopamine transporter | Transporter | Ki | 6.18 | WOMBAT-PK | |||||
Carbonic anhydrase 12 | Enzyme | Ki | 7.74 | CHEMBL | |||||
Carbonic anhydrase 4 | Enzyme | Ki | 6.06 | CHEMBL | |||||
Carbonic anhydrase 13 | Enzyme | Ki | 7.01 | CHEMBL | |||||
Prostaglandin G/H synthase 1 | Enzyme | IC50 | 7.30 | CHEMBL | |||||
Carbonic anhydrase 3 | Enzyme | Ki | 5.13 | CHEMBL | |||||
3-phosphoinositide-dependent protein kinase 1 | Kinase | IC50 | 4.32 | CHEMBL | |||||
Carbonic anhydrase 5A, mitochondrial | Enzyme | Ki | 6.10 | CHEMBL | |||||
Carbonic anhydrase 14 | Enzyme | Ki | 6.16 | CHEMBL | |||||
Carbonic anhydrase 7 | Enzyme | Ki | 5.66 | CHEMBL | |||||
Carbonic anhydrase 9 | Enzyme | Ki | 4.80 | CHEMBL | |||||
Carbonic anhydrase 1 | Enzyme | Ki | 4.30 | CHEMBL | |||||
Carbonic anhydrase 5B, mitochondrial | Enzyme | Ki | 7.03 | CHEMBL | |||||
Carbonic anhydrase 6 | Enzyme | Ki | 7.03 | CHEMBL | |||||
Mitogen-activated protein kinase 14 | Kinase | IC50 | 6.09 | CHEMBL | |||||
D(1A) dopamine receptor | GPCR | Ki | 4.85 | DRUG MATRIX | |||||
Progesterone receptor | Transcription factor | Ki | 5.63 | DRUG MATRIX | |||||
Prostaglandin G/H synthase 2 | Enzyme | IC50 | 7.40 | CHEMBL | |||||
Cytochrome c oxidase subunit 2 | Enzyme | IC50 | 7.22 | CHEMBL | |||||
Prostaglandin G/H synthase 1 | Enzyme | IC50 | 8.43 | CHEMBL | |||||
Carbonic anhydrase | Enzyme | Ki | 4.41 | CHEMBL | |||||
Alpha carbonic anhydrase | Unclassified | Ki | 7.47 | CHEMBL | |||||
Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase | Enzyme | Ki | 5.11 | CHEMBL | |||||
Prostaglandin G/H synthase 2 | Enzyme | IC50 | 7.24 | CHEMBL | |||||
Prostaglandin G/H synthase 2 | Enzyme | IC50 | 9.29 | CHEMBL | |||||
Prostaglandin G/H synthase 1 | Enzyme | IC50 | 9.15 | CHEMBL | |||||
Astrosclerin-3 | Unclassified | Ki | 6.14 | CHEMBL | |||||
Prostaglandin G/H synthase 2 | Enzyme | IC50 | 5.96 | CHEMBL | |||||
Beta-carbonic anhydrase 1 | Enzyme | Ki | 4.99 | CHEMBL | |||||
Carbonic anhydrase | Unclassified | Ki | 6.16 | CHEMBL | |||||
Delta carbonic anhydrase | Unclassified | Ki | 6.58 | CHEMBL | |||||
Carbonic anhydrase | Enzyme | Ki | 6.97 | CHEMBL | |||||
Cyclooxygenase 2; Prostaglandin G/H synthase-2; Uncharacterized protein | Enzyme | IC50 | 6.05 | CHEMBL | |||||
Prostaglandin G/H synthase 1 | Enzyme | IC50 | 5.25 | CHEMBL | |||||
Prostaglandin G/H synthase 1 | Enzyme | IC50 | 4.85 | CHEMBL | |||||
Carbonic anhydrase 15 | Enzyme | Ki | 7.35 | CHEMBL | |||||
Prostaglandin G/H synthase 1 | Enzyme | IC50 | 5.11 | CHEMBL | |||||
Cytochrome c oxidase subunit 1 | Unclassified | IC50 | 4.61 | CHEMBL | |||||
Carbonic anhydrase | Enzyme | Ki | 7.68 | CHEMBL | |||||
Carbonic anhydrase | Enzyme | Ki | 6.85 | CHEMBL | |||||
Carbonic anhydrase 2 | Enzyme | Ki | 6.15 | CHEMBL | |||||
Carbonic anhydrase 4 | Enzyme | Ki | 6.54 | CHEMBL | |||||
Carbonic anhydrase | Unclassified | Ki | 6.76 | CHEMBL | |||||
Carbonic anhydrase | Enzyme | Ki | 6.94 | CHEMBL |
ID | Source |
---|---|
4021143 | VUID |
N0000148596 | NUI |
D00567 | KEGG_DRUG |
4021143 | VANDF |
C0719198 | UMLSCUI |
CHEBI:41423 | CHEBI |
CEL | PDB_CHEM_ID |
CHEMBL118 | ChEMBL_ID |
DB00482 | DRUGBANK_ID |
D000068579 | MESH_DESCRIPTOR_UI |
2662 | PUBCHEM_CID |
2892 | IUPHAR_LIGAND_ID |
7767 | INN_ID |
JCX84Q7J1L | UNII |
140587 | RXNORM |
14020 | MMSL |
174627 | MMSL |
7872 | MMSL |
d04380 | MMSL |
007731 | NDDF |
116081000 | SNOMEDCT_US |
370187009 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
CELEBREX | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0025-1515 | CAPSULE | 50 mg | ORAL | NDA | 31 sections |
CELEBREX | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0025-1520 | CAPSULE | 100 mg | ORAL | NDA | 31 sections |
CELEBREX | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0025-1525 | CAPSULE | 200 mg | ORAL | NDA | 31 sections |
CELEBREX | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0025-1530 | CAPSULE | 400 mg | ORAL | NDA | 31 sections |
Celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-7165 | CAPSULE | 100 mg | ORAL | ANDA | 29 sections |
Celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-7166 | CAPSULE | 200 mg | ORAL | ANDA | 29 sections |
Celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-7170 | CAPSULE | 400 mg | ORAL | ANDA | 29 sections |
Celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-7306 | CAPSULE | 50 mg | ORAL | ANDA | 29 sections |
Celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-7150 | CAPSULE | 200 mg | ORAL | ANDA | 30 sections |
Celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-7160 | CAPSULE | 100 mg | ORAL | ANDA | 30 sections |
Celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-7165 | CAPSULE | 50 mg | ORAL | ANDA | 30 sections |
Celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-7170 | CAPSULE | 400 mg | ORAL | ANDA | 30 sections |
Celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0591-3982 | CAPSULE | 50 mg | ORAL | ANDA | 30 sections |
Celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0591-3983 | CAPSULE | 100 mg | ORAL | ANDA | 30 sections |
Celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0591-3984 | CAPSULE | 200 mg | ORAL | ANDA | 30 sections |
Celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0591-3985 | CAPSULE | 400 mg | ORAL | ANDA | 30 sections |
celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8297 | CAPSULE | 200 mg | ORAL | ANDA | 26 sections |
celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8338 | CAPSULE | 200 mg | ORAL | ANDA | 26 sections |
Celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-6502 | CAPSULE | 100 mg | ORAL | ANDA | 31 sections |
Celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-6503 | CAPSULE | 200 mg | ORAL | ANDA | 31 sections |
Celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10544-917 | CAPSULE | 200 mg | ORAL | NDA authorized generic | 33 sections |
Celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10544-918 | CAPSULE | 200 mg | ORAL | NDA authorized generic | 33 sections |
Celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10544-929 | CAPSULE | 200 mg | ORAL | NDA authorized generic | 33 sections |
Celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10544-953 | CAPSULE | 200 mg | ORAL | ANDA | 33 sections |
Celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10544-967 | CAPSULE | 200 mg | ORAL | NDA authorized generic | 33 sections |
celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-307 | CAPSULE | 50 mg | ORAL | ANDA | 27 sections |
celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-310 | CAPSULE | 400 mg | ORAL | ANDA | 27 sections |
celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-441 | CAPSULE | 100 mg | ORAL | ANDA | 27 sections |
celecoxib | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-442 | CAPSULE | 200 mg | ORAL | ANDA | 27 sections |
CELEBREX | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16590-045 | CAPSULE | 100 mg | ORAL | NDA | 33 sections |