hydrogen peroxide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
3281 7722-84-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • oxydol
  • hydrogen peroxide topical solution
  • hydrogen peroxide
A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
  • Molecular weight: 34.01
  • Formula: H2O2
  • CLOGP:
  • LIPINSKI: None
  • HAC: 2
  • HDO: 2
  • TPSA: 40.46
  • ALOGS:
  • ROTB: 0

Drug dosage:

DoseUnitRoute
60 mg O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Application site discolouration 73.09 35.82 10 233 928 90627276
Hypertrophic scar 64.46 35.82 6 237 12 90628192
Application site erythema 36.64 35.82 7 236 5201 90623003

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Gastritis erosive 55.07 37.62 12 289 6491 42614543
Shock haemorrhagic 44.16 37.62 12 289 16230 42604804

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Gastritis erosive 51.97 34.91 12 532 11988 110576767
Shock haemorrhagic 46.76 34.91 13 531 27234 110561521
Hypertrophic scar 39.62 34.91 4 540 11 110588744

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A01AB02 ALIMENTARY TRACT AND METABOLISM
STOMATOLOGICAL PREPARATIONS
STOMATOLOGICAL PREPARATIONS
Antiinfectives and antiseptics for local oral treatment
ATC D08AX01 DERMATOLOGICALS
ANTISEPTICS AND DISINFECTANTS
ANTISEPTICS AND DISINFECTANTS
Other antiseptics and disinfectants
ATC D11AX25 DERMATOLOGICALS
OTHER DERMATOLOGICAL PREPARATIONS
OTHER DERMATOLOGICAL PREPARATIONS
Other dermatologicals
ATC S02AA06 SENSORY ORGANS
OTOLOGICALS
ANTIINFECTIVES
Antiinfectives
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000891 Anti-Infective Agents, Local
MeSH PA D016877 Oxidants
CHEBI has role CHEBI:23357 cofactor
CHEBI has role CHEBI:33281 antimicrobial agent
CHEBI has role CHEBI:48219 disinfectant
CHEBI has role CHEBI:50902 genotoxin
CHEBI has role CHEBI:50910 neurotoxin
CHEBI has role CHEBI:59163 biomarker
CHEBI has role CHEBI:63248 oxidising agent
CHEBI has role CHEBI:63490 explosive
CHEBI has role CHEBI:65259 GABA antagonist
CHEBI has role CHEBI:68495 apoptosis inducer
CHEBI has role CHEBI:75771 mouse metabolite
CHEBI has role CHEBI:75772 <em>Saccharomyces cerevisiae </em> metabolite
CHEBI has role CHEBI:76967 human xenobiotic metabolite
CHEBI has role CHEBI:76971 <em>Escherichia coli</em> metabolite
CHEBI has role CHEBI:132717 bleaching agent
CHEBI has role CHEBI:149552 emetic

Related Drugs by ATC class:

A01AB Antiinfectives and antiseptics for local oral treatment 22 drugs
D08AX Other antiseptics and disinfectants 7 drugs
D11AX Other dermatologicals 20 drugs
S02AA Antiinfectives 17 drugs

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Antiseptic preparation indication 261276004




🐶 Veterinary Drug Use

SpeciesUseRelation
Fish Control mortality caused by saprolegniasis Indication
Fish Control mortality caused by bacterial gill disease associated with Flavobacterium branchiophilum Indication
Fish Control mortality caused by saprolegniasis Indication
Fish Control mortality caused by external columnaris disease associated with Flavobacterium columnare (Flexibacter columnaris) Indication
Fish Control mortality caused by external columnaris disease associated with Flavobacterium columnare (Flexibacter columnaris) Indication

🐶 Veterinary products

ProductApplicantIngredients
35% PEROX-AID Syndel USA 1

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.99 acidic
pKa2 12.0 acidic

Orange Book patent data (new drug applications)

Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRoutePatent numberPatent expiration datePatent use
40% ESKATA ACLARIS N209305 Dec. 14, 2017 DISCN SOLUTION TOPICAL 10098910 April 21, 2035 TREATMENT OF SEBORRHEIC KERATOSES THAT ARE RAISED
40% ESKATA ACLARIS N209305 Dec. 14, 2017 DISCN SOLUTION TOPICAL 9980983 April 21, 2035 TREATMENT OF SEBORRHEIC KERATOSES THAT ARE RAISED
40% ESKATA ACLARIS N209305 Dec. 14, 2017 DISCN SOLUTION TOPICAL 9675639 July 4, 2035 TREATMENT OF SEBORRHEIC KERATOSES THAT ARE RAISED

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
BBX060AN9V UNII
D00008 KEGG_DRUG
4019590 VANDF
C0020281 UMLSCUI
CHEBI:16240 CHEBI
PEO PDB_CHEM_ID
CHEMBL71595 ChEMBL_ID
784 PUBCHEM_CID
DB11091 DRUGBANK_ID
D006861 MESH_DESCRIPTOR_UI
372426 RXNORM
35389 MMSL
35390 MMSL
4847 MMSL
5359 MMSL
003157 NDDF
31231007 SNOMEDCT_US
387171003 SNOMEDCT_US
BBX060AN9V INXIGHT DRUGS

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
PEROXYL MOUTH SORE MILD MINT HUMAN OTC DRUG LABEL 1 0126-0083 RINSE 15 mg BUCCAL OTC MONOGRAPH NOT FINAL 13 sections
PEROXYL MOUTH SORE MILD MINT HUMAN OTC DRUG LABEL 1 0126-0083 RINSE 15 mg BUCCAL OTC MONOGRAPH NOT FINAL 13 sections
Sore Mouth Cleanser HUMAN OTC DRUG LABEL 1 0363-0085 MOUTHWASH 15 mg TOPICAL OTC Monograph Drug 12 sections
Hydrogen Peroxide3 Percent HUMAN OTC DRUG LABEL 1 0363-0268 LIQUID 2.65 mL TOPICAL OTC Monograph Drug 13 sections
Hydrogen Peroxide HUMAN OTC DRUG LABEL 1 0363-0871 SOLUTION 30 mg TOPICAL OTC Monograph Drug 13 sections
Oral Sore Antiseptic HUMAN OTC DRUG LABEL 2 0363-1045 LIQUID 1.50 mg ORAL OTC Monograph Drug 13 sections
Walgreens 3 Hydrogen Peroxide Wipes HUMAN OTC DRUG LABEL 1 0363-9653 CLOTH 0.03 g TOPICAL OTC Monograph Drug 13 sections
Humco Hydrogen Peroxide HUMAN OTC DRUG LABEL 1 0395-1113 LIQUID 30 mg TOPICAL OTC Monograph Drug 12 sections
Humco Hydrogen Peroxide HUMAN OTC DRUG LABEL 1 0395-9116 LIQUID 30 mg TOPICAL OTC monograph not final 12 sections
Hydrogen Peroxide HUMAN OTC DRUG LABEL 1 0404-0001 SOLUTION 30 mg TOPICAL OTC Monograph Drug 14 sections
Hydrogen Peroxide HUMAN OTC DRUG LABEL 1 0869-0871 SOLUTION 30 mg TOPICAL OTC Monograph Drug 13 sections
First Aid Only Hydrogen Peroxide HUMAN OTC DRUG LABEL 1 0924-0171 SPRAY 30 mL TOPICAL OTC monograph not final 11 sections
Hydrogen Peroxide Antiseptic HUMAN OTC DRUG LABEL 1 0924-0932 SPRAY 30 mL TOPICAL OTC monograph not final 11 sections
First Aid Only Hydrogen Peroxide 3% HUMAN OTC DRUG LABEL 1 0924-0935 SPRAY 30 mg TOPICAL OTC Monograph Drug 13 sections
Perio Armor HUMAN OTC DRUG LABEL 1 10129-018 GEL 17 g PERIODONTAL unapproved drug other 12 sections
Perio Armor HUMAN OTC DRUG LABEL 1 10129-019 GEL 17 g DENTAL unapproved drug other 12 sections
Perio Armor HUMAN OTC DRUG LABEL 1 10129-020 GEL 17 g DENTAL unapproved drug other 12 sections
Perio Armor HUMAN OTC DRUG LABEL 1 10129-032 GEL 17 g DENTAL unapproved drug other 12 sections
Perio Armor-X HUMAN OTC DRUG LABEL 1 10129-038 GEL 1.70 g PERIODONTAL OTC monograph not final 12 sections
Perio Armor-X HUMAN OTC DRUG LABEL 1 10129-039 GEL 1.70 g PERIODONTAL OTC monograph not final 12 sections
Perio Armor-X HUMAN OTC DRUG LABEL 1 10129-042 GEL 1.70 g PERIODONTAL OTC monograph not final 12 sections
Perio Plus HUMAN OTC DRUG LABEL 1 10129-043 GEL 1.70 g DENTAL OTC monograph not final 12 sections
Perio Max Plus HUMAN OTC DRUG LABEL 1 10129-044 GEL 1.70 g DENTAL OTC monograph not final 12 sections
Hydrogen Peroxide HUMAN OTC DRUG LABEL 1 10202-001 SOLUTION 30 mg TOPICAL OTC Monograph Drug 13 sections
Orajel Antiseptic Rinse For All Mouth Sores HUMAN OTC DRUG LABEL 2 10237-760 LIQUID 15 mg ORAL OTC Monograph Drug 12 sections
Orajel Antiseptic Alcohol-Free Mouth Sore Rinse HUMAN OTC DRUG LABEL 2 10237-784 LIQUID 15 mg ORAL OTC Monograph Drug 11 sections
Orajel 2x Gum Pain Alcohol-Free HUMAN OTC DRUG LABEL 2 10237-799 RINSE 15 mg ORAL OTC Monograph Drug 14 sections
Hydrogen Peroxide HUMAN OTC DRUG LABEL 1 10565-001 SOLUTION 3 mL TOPICAL OTC Monograph Drug 14 sections
Hydrogen Peroxide HUMAN OTC DRUG LABEL 1 11344-871 SOLUTION 30 mg TOPICAL OTC Monograph Drug 13 sections
Hydrogen Peroxide3 Percent HUMAN OTC DRUG LABEL 1 11673-268 LIQUID 2.65 mL TOPICAL OTC Monograph Drug 13 sections