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| Stem definition | Drug id | CAS RN |
|---|---|---|
| 3281 | 7722-84-1 |
| Dose | Unit | Route |
|---|---|---|
| 60 | mg | O |
None
None
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Application site discolouration | 73.09 | 35.82 | 10 | 233 | 928 | 90627276 |
| Hypertrophic scar | 64.46 | 35.82 | 6 | 237 | 12 | 90628192 |
| Application site erythema | 36.64 | 35.82 | 7 | 236 | 5201 | 90623003 |
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Gastritis erosive | 55.07 | 37.62 | 12 | 289 | 6491 | 42614543 |
| Shock haemorrhagic | 44.16 | 37.62 | 12 | 289 | 16230 | 42604804 |
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Gastritis erosive | 51.97 | 34.91 | 12 | 532 | 11988 | 110576767 |
| Shock haemorrhagic | 46.76 | 34.91 | 13 | 531 | 27234 | 110561521 |
| Hypertrophic scar | 39.62 | 34.91 | 4 | 540 | 11 | 110588744 |
None
| Source | Code | Description |
|---|---|---|
| ATC | A01AB02 | ALIMENTARY TRACT AND METABOLISM STOMATOLOGICAL PREPARATIONS STOMATOLOGICAL PREPARATIONS Antiinfectives and antiseptics for local oral treatment |
| ATC | D08AX01 | DERMATOLOGICALS ANTISEPTICS AND DISINFECTANTS ANTISEPTICS AND DISINFECTANTS Other antiseptics and disinfectants |
| ATC | D11AX25 | DERMATOLOGICALS OTHER DERMATOLOGICAL PREPARATIONS OTHER DERMATOLOGICAL PREPARATIONS Other dermatologicals |
| ATC | S02AA06 | SENSORY ORGANS OTOLOGICALS ANTIINFECTIVES Antiinfectives |
| MeSH PA | D000890 | Anti-Infective Agents |
| MeSH PA | D000891 | Anti-Infective Agents, Local |
| MeSH PA | D016877 | Oxidants |
| CHEBI has role | CHEBI:23357 | cofactor |
| CHEBI has role | CHEBI:33281 | antimicrobial agent |
| CHEBI has role | CHEBI:48219 | disinfectant |
| CHEBI has role | CHEBI:50902 | genotoxin |
| CHEBI has role | CHEBI:50910 | neurotoxin |
| CHEBI has role | CHEBI:59163 | biomarker |
| CHEBI has role | CHEBI:63248 | oxidising agent |
| CHEBI has role | CHEBI:63490 | explosive |
| CHEBI has role | CHEBI:65259 | GABA antagonist |
| CHEBI has role | CHEBI:68495 | apoptosis inducer |
| CHEBI has role | CHEBI:75771 | mouse metabolite |
| CHEBI has role | CHEBI:75772 | <em>Saccharomyces cerevisiae </em> metabolite |
| CHEBI has role | CHEBI:76967 | human xenobiotic metabolite |
| CHEBI has role | CHEBI:76971 | <em>Escherichia coli</em> metabolite |
| CHEBI has role | CHEBI:132717 | bleaching agent |
| CHEBI has role | CHEBI:149552 | emetic |
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Antiseptic preparation | indication | 261276004 |
| Species | Use | Relation |
|---|---|---|
| Fish | Control mortality caused by saprolegniasis | Indication |
| Fish | Control mortality caused by bacterial gill disease associated with Flavobacterium branchiophilum | Indication |
| Fish | Control mortality caused by saprolegniasis | Indication |
| Fish | Control mortality caused by external columnaris disease associated with Flavobacterium columnare (Flexibacter columnaris) | Indication |
| Fish | Control mortality caused by external columnaris disease associated with Flavobacterium columnare (Flexibacter columnaris) | Indication |
| Product | Applicant | Ingredients |
|---|---|---|
| 35% PEROX-AID | Syndel USA | 1 |
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 4.99 | acidic |
| pKa2 | 12.0 | acidic |
| Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Patent number | Patent expiration date | Patent use |
|---|---|---|---|---|---|---|---|---|---|---|
| 40% | ESKATA | ACLARIS | N209305 | Dec. 14, 2017 | DISCN | SOLUTION | TOPICAL | 10098910 | April 21, 2035 | TREATMENT OF SEBORRHEIC KERATOSES THAT ARE RAISED |
| 40% | ESKATA | ACLARIS | N209305 | Dec. 14, 2017 | DISCN | SOLUTION | TOPICAL | 9980983 | April 21, 2035 | TREATMENT OF SEBORRHEIC KERATOSES THAT ARE RAISED |
| 40% | ESKATA | ACLARIS | N209305 | Dec. 14, 2017 | DISCN | SOLUTION | TOPICAL | 9675639 | July 4, 2035 | TREATMENT OF SEBORRHEIC KERATOSES THAT ARE RAISED |
None
None
| ID | Source |
|---|---|
| BBX060AN9V | UNII |
| D00008 | KEGG_DRUG |
| 4019590 | VANDF |
| C0020281 | UMLSCUI |
| CHEBI:16240 | CHEBI |
| PEO | PDB_CHEM_ID |
| CHEMBL71595 | ChEMBL_ID |
| 784 | PUBCHEM_CID |
| DB11091 | DRUGBANK_ID |
| D006861 | MESH_DESCRIPTOR_UI |
| 372426 | RXNORM |
| 35389 | MMSL |
| 35390 | MMSL |
| 4847 | MMSL |
| 5359 | MMSL |
| 003157 | NDDF |
| 31231007 | SNOMEDCT_US |
| 387171003 | SNOMEDCT_US |
| BBX060AN9V | INXIGHT DRUGS |
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| PEROXYL MOUTH SORE MILD MINT | HUMAN OTC DRUG LABEL | 1 | 0126-0083 | RINSE | 15 mg | BUCCAL | OTC MONOGRAPH NOT FINAL | 13 sections |
| PEROXYL MOUTH SORE MILD MINT | HUMAN OTC DRUG LABEL | 1 | 0126-0083 | RINSE | 15 mg | BUCCAL | OTC MONOGRAPH NOT FINAL | 13 sections |
| Sore Mouth Cleanser | HUMAN OTC DRUG LABEL | 1 | 0363-0085 | MOUTHWASH | 15 mg | TOPICAL | OTC Monograph Drug | 12 sections |
| Hydrogen Peroxide3 Percent | HUMAN OTC DRUG LABEL | 1 | 0363-0268 | LIQUID | 2.65 mL | TOPICAL | OTC Monograph Drug | 13 sections |
| Hydrogen Peroxide | HUMAN OTC DRUG LABEL | 1 | 0363-0871 | SOLUTION | 30 mg | TOPICAL | OTC Monograph Drug | 13 sections |
| Oral Sore Antiseptic | HUMAN OTC DRUG LABEL | 2 | 0363-1045 | LIQUID | 1.50 mg | ORAL | OTC Monograph Drug | 13 sections |
| Walgreens 3 Hydrogen Peroxide Wipes | HUMAN OTC DRUG LABEL | 1 | 0363-9653 | CLOTH | 0.03 g | TOPICAL | OTC Monograph Drug | 13 sections |
| Humco Hydrogen Peroxide | HUMAN OTC DRUG LABEL | 1 | 0395-1113 | LIQUID | 30 mg | TOPICAL | OTC Monograph Drug | 12 sections |
| Humco Hydrogen Peroxide | HUMAN OTC DRUG LABEL | 1 | 0395-9116 | LIQUID | 30 mg | TOPICAL | OTC monograph not final | 12 sections |
| Hydrogen Peroxide | HUMAN OTC DRUG LABEL | 1 | 0404-0001 | SOLUTION | 30 mg | TOPICAL | OTC Monograph Drug | 14 sections |
| Hydrogen Peroxide | HUMAN OTC DRUG LABEL | 1 | 0869-0871 | SOLUTION | 30 mg | TOPICAL | OTC Monograph Drug | 13 sections |
| First Aid Only Hydrogen Peroxide | HUMAN OTC DRUG LABEL | 1 | 0924-0171 | SPRAY | 30 mL | TOPICAL | OTC monograph not final | 11 sections |
| Hydrogen Peroxide Antiseptic | HUMAN OTC DRUG LABEL | 1 | 0924-0932 | SPRAY | 30 mL | TOPICAL | OTC monograph not final | 11 sections |
| First Aid Only Hydrogen Peroxide 3% | HUMAN OTC DRUG LABEL | 1 | 0924-0935 | SPRAY | 30 mg | TOPICAL | OTC Monograph Drug | 13 sections |
| Perio Armor | HUMAN OTC DRUG LABEL | 1 | 10129-018 | GEL | 17 g | PERIODONTAL | unapproved drug other | 12 sections |
| Perio Armor | HUMAN OTC DRUG LABEL | 1 | 10129-019 | GEL | 17 g | DENTAL | unapproved drug other | 12 sections |
| Perio Armor | HUMAN OTC DRUG LABEL | 1 | 10129-020 | GEL | 17 g | DENTAL | unapproved drug other | 12 sections |
| Perio Armor | HUMAN OTC DRUG LABEL | 1 | 10129-032 | GEL | 17 g | DENTAL | unapproved drug other | 12 sections |
| Perio Armor-X | HUMAN OTC DRUG LABEL | 1 | 10129-038 | GEL | 1.70 g | PERIODONTAL | OTC monograph not final | 12 sections |
| Perio Armor-X | HUMAN OTC DRUG LABEL | 1 | 10129-039 | GEL | 1.70 g | PERIODONTAL | OTC monograph not final | 12 sections |
| Perio Armor-X | HUMAN OTC DRUG LABEL | 1 | 10129-042 | GEL | 1.70 g | PERIODONTAL | OTC monograph not final | 12 sections |
| Perio Plus | HUMAN OTC DRUG LABEL | 1 | 10129-043 | GEL | 1.70 g | DENTAL | OTC monograph not final | 12 sections |
| Perio Max Plus | HUMAN OTC DRUG LABEL | 1 | 10129-044 | GEL | 1.70 g | DENTAL | OTC monograph not final | 12 sections |
| Hydrogen Peroxide | HUMAN OTC DRUG LABEL | 1 | 10202-001 | SOLUTION | 30 mg | TOPICAL | OTC Monograph Drug | 13 sections |
| Orajel Antiseptic Rinse For All Mouth Sores | HUMAN OTC DRUG LABEL | 2 | 10237-760 | LIQUID | 15 mg | ORAL | OTC Monograph Drug | 12 sections |
| Orajel Antiseptic Alcohol-Free Mouth Sore Rinse | HUMAN OTC DRUG LABEL | 2 | 10237-784 | LIQUID | 15 mg | ORAL | OTC Monograph Drug | 11 sections |
| Orajel 2x Gum Pain Alcohol-Free | HUMAN OTC DRUG LABEL | 2 | 10237-799 | RINSE | 15 mg | ORAL | OTC Monograph Drug | 14 sections |
| Hydrogen Peroxide | HUMAN OTC DRUG LABEL | 1 | 10565-001 | SOLUTION | 3 mL | TOPICAL | OTC Monograph Drug | 14 sections |
| Hydrogen Peroxide | HUMAN OTC DRUG LABEL | 1 | 11344-871 | SOLUTION | 30 mg | TOPICAL | OTC Monograph Drug | 13 sections |
| Hydrogen Peroxide3 Percent | HUMAN OTC DRUG LABEL | 1 | 11673-268 | LIQUID | 2.65 mL | TOPICAL | OTC Monograph Drug | 13 sections |