eosin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4466 17372-87-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • eosin
  • eosin yellowish
  • bromofluorescein
  • tetrabromofluorescein
  • sodium eosin
  • sodium eosine
  • Molecular weight: 647.90
  • Formula: C20H8Br4O5
  • CLOGP: 5.49
  • LIPINSKI: 2
  • HAC: 5
  • HDO: 2
  • TPSA: 75.99
  • ALOGS: -5.53
  • ROTB: 0

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC D08AX02 DERMATOLOGICALS
ANTISEPTICS AND DISINFECTANTS
ANTISEPTICS AND DISINFECTANTS
Other antiseptics and disinfectants
CHEBI has role CHEBI:51217 fluorochromes
CHEBI has role CHEBI:77178 biological stain

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 5.82 acidic
pKa2 6.43 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Protein arginine N-methyltransferase 1 Enzyme IC50 6 CHEMBL
RmtA Enzyme IC50 4.74 CHEMBL

External reference:

IDSource
4020642 VUID
N0000167369 NUI
4020642 VANDF
CHEBI:52053 CHEBI
CHEMBL408917 ChEMBL_ID
DB13706 DRUGBANK_ID
1310593 RXNORM
NOCODE MMSL
009250 NDDF
010155 NDDF
256012001 SNOMEDCT_US
411353000 SNOMEDCT_US
C0014448 UMLSCUI
11048 PUBCHEM_CID
2730CL9N7C UNII

Pharmaceutical products:

None