Stem definition | Drug id | CAS RN |
---|---|---|
corticosteroids, except prednisolone derivatives | 1388 | 50-23-7 |
Dose | Unit | Route |
---|---|---|
30 | mg | O |
30 | mg | P |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 1 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 0.42 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 353.81 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
Vd (Volume of distribution) | 0.38 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 5.70 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.20 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 1.60 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
May 27, 2021 | EMA | Diurnal Europe B.V. | |
Aug. 5, 1952 | FDA | MERCK |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Infusion related reaction | 468.81 | 9.37 | 1300 | 143497 | 168257 | 50292070 |
Pericarditis | 372.56 | 9.37 | 745 | 144052 | 77944 | 50382383 |
Anti-cyclic citrullinated peptide antibody positive | 365.45 | 9.37 | 694 | 144103 | 69893 | 50390434 |
Completed suicide | 347.00 | 9.37 | 6 | 144791 | 131883 | 50328444 |
Wound | 328.24 | 9.37 | 847 | 143950 | 104947 | 50355380 |
Rheumatoid factor positive | 312.71 | 9.37 | 533 | 144264 | 49326 | 50411001 |
Adrenocortical insufficiency acute | 312.22 | 9.37 | 127 | 144670 | 1317 | 50459010 |
Discomfort | 300.16 | 9.37 | 832 | 143965 | 107548 | 50352779 |
Hand deformity | 271.33 | 9.37 | 763 | 144034 | 99436 | 50360891 |
Glossodynia | 235.56 | 9.37 | 797 | 144000 | 114772 | 50345555 |
Duodenal ulcer perforation | 234.17 | 9.37 | 447 | 144350 | 45164 | 50415163 |
Helicobacter infection | 222.56 | 9.37 | 460 | 144337 | 49242 | 50411085 |
Synovitis | 221.33 | 9.37 | 818 | 143979 | 123047 | 50337280 |
Toxicity to various agents | 213.24 | 9.37 | 177 | 144620 | 212322 | 50248005 |
Intentional product use issue | 204.51 | 9.37 | 582 | 144215 | 76336 | 50383991 |
Pemphigus | 200.96 | 9.37 | 777 | 144020 | 119389 | 50340938 |
Systemic lupus erythematosus | 200.15 | 9.37 | 865 | 143932 | 139757 | 50320570 |
Adrenal insufficiency | 188.44 | 9.37 | 218 | 144579 | 14025 | 50446302 |
Hepatic enzyme increased | 182.59 | 9.37 | 828 | 143969 | 136552 | 50323775 |
Drug hypersensitivity | 181.87 | 9.37 | 1285 | 143512 | 249725 | 50210602 |
Arthropathy | 181.81 | 9.37 | 913 | 143884 | 156993 | 50303334 |
Steroid withdrawal syndrome | 173.66 | 9.37 | 63 | 144734 | 464 | 50459863 |
Hypersensitivity | 164.35 | 9.37 | 1116 | 143681 | 214045 | 50246282 |
Death | 153.92 | 9.37 | 451 | 144346 | 324928 | 50135399 |
Swelling | 141.11 | 9.37 | 1021 | 143776 | 199851 | 50260476 |
Product use issue | 136.77 | 9.37 | 812 | 143985 | 148663 | 50311664 |
Drug abuse | 130.13 | 9.37 | 11 | 144786 | 59835 | 50400492 |
Abdominal discomfort | 120.21 | 9.37 | 1099 | 143698 | 230542 | 50229785 |
Colitis ulcerative | 114.72 | 9.37 | 187 | 144610 | 16667 | 50443660 |
Blister | 114.25 | 9.37 | 516 | 144281 | 84902 | 50375425 |
Intentional overdose | 108.75 | 9.37 | 23 | 144774 | 62481 | 50397846 |
Fall | 108.61 | 9.37 | 541 | 144256 | 334391 | 50125936 |
Febrile bone marrow aplasia | 106.85 | 9.37 | 110 | 144687 | 6201 | 50454126 |
Alopecia | 103.98 | 9.37 | 1115 | 143682 | 243932 | 50216395 |
Drug intolerance | 98.60 | 9.37 | 1009 | 143788 | 218095 | 50242232 |
Rheumatic fever | 97.46 | 9.37 | 174 | 144623 | 16693 | 50443634 |
Craniopharyngioma | 96.50 | 9.37 | 30 | 144767 | 127 | 50460200 |
Overdose | 96.34 | 9.37 | 86 | 144711 | 99641 | 50360686 |
Maternal exposure during pregnancy | 93.70 | 9.37 | 779 | 144018 | 158999 | 50301328 |
Rash | 92.76 | 9.37 | 1761 | 143036 | 435710 | 50024617 |
Condition aggravated | 92.61 | 9.37 | 1275 | 143522 | 295783 | 50164544 |
Blood pressure fluctuation | 92.18 | 9.37 | 268 | 144529 | 35555 | 50424772 |
Drug interaction | 84.21 | 9.37 | 291 | 144506 | 199330 | 50260997 |
Swollen joint count increased | 82.83 | 9.37 | 151 | 144646 | 14722 | 50445605 |
Hypofibrinogenaemia | 82.75 | 9.37 | 47 | 144750 | 1065 | 50459262 |
Irritable bowel syndrome | 80.53 | 9.37 | 326 | 144471 | 51115 | 50409212 |
Sleep disorder due to general medical condition, insomnia type | 74.96 | 9.37 | 229 | 144568 | 31218 | 50429109 |
Pituitary tumour benign | 73.89 | 9.37 | 52 | 144745 | 1729 | 50458598 |
Secondary adrenocortical insufficiency | 73.64 | 9.37 | 44 | 144753 | 1099 | 50459228 |
Muscle injury | 69.47 | 9.37 | 249 | 144548 | 36862 | 50423465 |
Hip arthroplasty | 69.21 | 9.37 | 218 | 144579 | 30211 | 50430116 |
Folliculitis | 66.58 | 9.37 | 255 | 144542 | 38970 | 50421357 |
Product dose omission issue | 62.93 | 9.37 | 291 | 144506 | 183547 | 50276780 |
Type 2 diabetes mellitus | 59.60 | 9.37 | 225 | 144572 | 34150 | 50426177 |
Device expulsion | 55.82 | 9.37 | 8 | 144789 | 28814 | 50431513 |
Suicide attempt | 53.15 | 9.37 | 42 | 144755 | 51690 | 50408637 |
Joint swelling | 52.00 | 9.37 | 988 | 143809 | 244298 | 50216029 |
Off label use | 51.73 | 9.37 | 1747 | 143050 | 472679 | 49987648 |
Knee arthroplasty | 48.23 | 9.37 | 217 | 144580 | 35629 | 50424698 |
Contraindicated product administered | 47.78 | 9.37 | 643 | 144154 | 148315 | 50312012 |
Inappropriate schedule of product administration | 47.40 | 9.37 | 360 | 144437 | 71471 | 50388856 |
Injury | 46.74 | 9.37 | 269 | 144528 | 48656 | 50411671 |
Cardiac failure congestive | 45.82 | 9.37 | 109 | 144688 | 84273 | 50376054 |
Cortisol decreased | 45.34 | 9.37 | 31 | 144766 | 983 | 50459344 |
Adrenal suppression | 44.63 | 9.37 | 29 | 144768 | 843 | 50459484 |
Sedation | 44.40 | 9.37 | 16 | 144781 | 30594 | 50429733 |
Drug level below therapeutic | 44.11 | 9.37 | 54 | 144743 | 3686 | 50456641 |
Cerebrovascular accident | 44.07 | 9.37 | 132 | 144665 | 94548 | 50365779 |
Urticaria thermal | 43.43 | 9.37 | 17 | 144780 | 158 | 50460169 |
Frequent bowel movements | 42.62 | 9.37 | 111 | 144686 | 13807 | 50446520 |
Hyperadrenocorticism | 42.30 | 9.37 | 20 | 144777 | 305 | 50460022 |
Acute kidney injury | 41.71 | 9.37 | 434 | 144363 | 227624 | 50232703 |
Poor venous access | 40.84 | 9.37 | 91 | 144706 | 10249 | 50450078 |
Injection site reaction | 40.59 | 9.37 | 50 | 144747 | 49982 | 50410345 |
Anaemia | 40.45 | 9.37 | 495 | 144302 | 251961 | 50208366 |
Drug tolerance decreased | 38.90 | 9.37 | 83 | 144714 | 9077 | 50451250 |
Hypothalamic pituitary adrenal axis suppression | 38.45 | 9.37 | 15 | 144782 | 138 | 50460189 |
Musculoskeletal injury | 37.81 | 9.37 | 14 | 144783 | 110 | 50460217 |
Wrong technique in product usage process | 37.61 | 9.37 | 63 | 144734 | 55447 | 50404880 |
Injection site erythema | 37.43 | 9.37 | 101 | 144696 | 74835 | 50385492 |
Myocardial infarction | 37.34 | 9.37 | 130 | 144667 | 88897 | 50371430 |
Female genital tract fistula | 37.03 | 9.37 | 49 | 144748 | 3617 | 50456710 |
Nausea | 36.75 | 9.37 | 1648 | 143149 | 703750 | 49756577 |
Cognitive disorder | 35.89 | 9.37 | 44 | 144753 | 44079 | 50416248 |
Serotonin syndrome | 35.71 | 9.37 | 13 | 144784 | 24700 | 50435627 |
Hypothalamo-pituitary disorder | 35.54 | 9.37 | 23 | 144774 | 664 | 50459663 |
Intentional self-injury | 35.41 | 9.37 | 11 | 144786 | 23101 | 50437226 |
Malignant neoplasm progression | 34.64 | 9.37 | 91 | 144706 | 68033 | 50392294 |
Hypopituitarism | 34.48 | 9.37 | 25 | 144772 | 872 | 50459455 |
Insulin-like growth factor increased | 34.21 | 9.37 | 24 | 144773 | 794 | 50459533 |
Live birth | 34.10 | 9.37 | 114 | 144683 | 16294 | 50444033 |
Human bocavirus infection | 33.79 | 9.37 | 18 | 144779 | 358 | 50459969 |
Coma | 33.72 | 9.37 | 70 | 144727 | 56809 | 50403518 |
Interstitial lung disease | 33.63 | 9.37 | 63 | 144734 | 53113 | 50407214 |
Syncope | 33.49 | 9.37 | 166 | 144631 | 102836 | 50357491 |
Blood cholesterol increased | 33.26 | 9.37 | 271 | 144526 | 54944 | 50405383 |
Treatment failure | 32.85 | 9.37 | 565 | 144232 | 137072 | 50323255 |
Injection site swelling | 32.59 | 9.37 | 43 | 144754 | 41730 | 50418597 |
Respiratory arrest | 32.58 | 9.37 | 23 | 144774 | 29986 | 50430341 |
Neoplasm recurrence | 32.58 | 9.37 | 37 | 144760 | 2332 | 50457995 |
Faecal calprotectin increased | 31.94 | 9.37 | 35 | 144762 | 2120 | 50458207 |
Intentional product misuse | 31.69 | 9.37 | 53 | 144744 | 46681 | 50413646 |
Blood creatinine increased | 31.41 | 9.37 | 112 | 144685 | 76048 | 50384279 |
Renal impairment | 31.38 | 9.37 | 111 | 144686 | 75550 | 50384777 |
Injection site pain | 31.11 | 9.37 | 188 | 144609 | 110836 | 50349491 |
Breast cancer | 30.63 | 9.37 | 47 | 144750 | 42843 | 50417484 |
Cardio-respiratory arrest | 30.55 | 9.37 | 68 | 144729 | 53824 | 50406503 |
Therapeutic product effect incomplete | 30.03 | 9.37 | 147 | 144650 | 91368 | 50368959 |
Cardiac failure | 29.93 | 9.37 | 114 | 144683 | 75926 | 50384401 |
Chronic obstructive pulmonary disease | 29.82 | 9.37 | 68 | 144729 | 53367 | 50406960 |
Heart rate irregular | 29.73 | 9.37 | 122 | 144675 | 19238 | 50441089 |
Atrial fibrillation | 29.72 | 9.37 | 170 | 144627 | 101575 | 50358752 |
Full blood count abnormal | 29.50 | 9.37 | 15 | 144782 | 23373 | 50436954 |
Body temperature fluctuation | 29.17 | 9.37 | 32 | 144765 | 1941 | 50458386 |
Suicidal ideation | 28.92 | 9.37 | 73 | 144724 | 55312 | 50405015 |
Asphyxia | 28.84 | 9.37 | 54 | 144743 | 5373 | 50454954 |
Colitis | 28.80 | 9.37 | 199 | 144598 | 38330 | 50421997 |
Tendonitis | 28.67 | 9.37 | 109 | 144688 | 16596 | 50443731 |
Therapeutic product effect decreased | 28.09 | 9.37 | 546 | 144251 | 135504 | 50324823 |
Perioral dermatitis | 27.87 | 9.37 | 12 | 144785 | 145 | 50460182 |
Hypophysitis | 27.67 | 9.37 | 28 | 144769 | 1546 | 50458781 |
Drug withdrawal syndrome | 27.52 | 9.37 | 19 | 144778 | 25062 | 50435265 |
Platelet count decreased | 27.47 | 9.37 | 172 | 144625 | 100554 | 50359773 |
Balance disorder | 27.03 | 9.37 | 107 | 144690 | 70483 | 50389844 |
Gastrointestinal haemorrhage | 26.91 | 9.37 | 113 | 144684 | 73208 | 50387119 |
Rheumatoid arthritis | 26.72 | 9.37 | 413 | 144384 | 202137 | 50258190 |
Haemoglobin decreased | 26.67 | 9.37 | 234 | 144563 | 126982 | 50333345 |
Electrocardiogram QT prolonged | 26.61 | 9.37 | 69 | 144728 | 51817 | 50408510 |
Impaired healing | 26.08 | 9.37 | 310 | 144487 | 69476 | 50390851 |
Normal tension glaucoma | 25.90 | 9.37 | 8 | 144789 | 33 | 50460294 |
Therapeutic response shortened | 25.85 | 9.37 | 62 | 144735 | 7327 | 50453000 |
Insulin-like growth factor decreased | 25.68 | 9.37 | 15 | 144782 | 359 | 50459968 |
Natural killer-cell leukaemia | 25.63 | 9.37 | 10 | 144787 | 92 | 50460235 |
Anal fistula | 25.19 | 9.37 | 35 | 144762 | 2707 | 50457620 |
Urticaria | 24.76 | 9.37 | 514 | 144283 | 129047 | 50331280 |
Red blood cell sedimentation rate abnormal | 24.64 | 9.37 | 8 | 144789 | 16335 | 50443992 |
Faecal volume decreased | 24.43 | 9.37 | 11 | 144786 | 149 | 50460178 |
Clostridium difficile colitis | 24.31 | 9.37 | 108 | 144689 | 17634 | 50442693 |
Hospitalisation | 24.14 | 9.37 | 106 | 144691 | 67831 | 50392496 |
Antithrombin III | 23.98 | 9.37 | 11 | 144786 | 156 | 50460171 |
Depressed level of consciousness | 23.76 | 9.37 | 73 | 144724 | 51880 | 50408447 |
Oedema peripheral | 23.67 | 9.37 | 314 | 144483 | 157647 | 50302680 |
Perfume sensitivity | 23.49 | 9.37 | 17 | 144780 | 591 | 50459736 |
Lactic acidosis | 23.39 | 9.37 | 37 | 144760 | 33318 | 50427009 |
Accidental exposure to product | 23.33 | 9.37 | 19 | 144778 | 23038 | 50437289 |
Anal fissure | 23.26 | 9.37 | 36 | 144761 | 3069 | 50457258 |
Proctalgia | 23.19 | 9.37 | 47 | 144750 | 4956 | 50455371 |
Drug level decreased | 23.05 | 9.37 | 55 | 144742 | 6478 | 50453849 |
Tendon pain | 22.97 | 9.37 | 35 | 144762 | 2943 | 50457384 |
Blood creatine phosphokinase increased | 22.84 | 9.37 | 25 | 144772 | 26342 | 50433985 |
Lower respiratory tract infection | 22.77 | 9.37 | 391 | 144406 | 94810 | 50365517 |
Bradycardia | 22.60 | 9.37 | 101 | 144696 | 64325 | 50396002 |
Mucous stools | 22.24 | 9.37 | 34 | 144763 | 2868 | 50457459 |
Somnolence | 22.17 | 9.37 | 311 | 144486 | 154674 | 50305653 |
Allergy test positive | 22.04 | 9.37 | 14 | 144783 | 391 | 50459936 |
Wheezing | 22.04 | 9.37 | 273 | 144524 | 61774 | 50398553 |
Metastases to bone | 22.02 | 9.37 | 12 | 144785 | 17983 | 50442344 |
Gastroenteritis norovirus | 21.87 | 9.37 | 26 | 144771 | 1721 | 50458606 |
Macular degeneration | 21.77 | 9.37 | 7 | 144790 | 14381 | 50445946 |
Maternal exposure timing unspecified | 21.75 | 9.37 | 38 | 144759 | 3582 | 50456745 |
Ill-defined disorder | 21.40 | 9.37 | 245 | 144552 | 54409 | 50405918 |
Cardiac disorder | 21.40 | 9.37 | 58 | 144739 | 42921 | 50417406 |
Pneumonia | 21.28 | 9.37 | 876 | 143921 | 377525 | 50082802 |
Weight increased | 21.27 | 9.37 | 741 | 144056 | 201150 | 50259177 |
Deep vein thrombosis postoperative | 21.21 | 9.37 | 25 | 144772 | 1640 | 50458687 |
Haematochezia | 21 | 9.37 | 190 | 144607 | 39692 | 50420635 |
Pruritus | 20.95 | 9.37 | 1002 | 143795 | 282566 | 50177761 |
Excessive eye blinking | 20.73 | 9.37 | 19 | 144778 | 927 | 50459400 |
Airway peak pressure increased | 20.70 | 9.37 | 12 | 144785 | 283 | 50460044 |
Adrenal disorder | 20.67 | 9.37 | 22 | 144775 | 1289 | 50459038 |
Secondary immunodeficiency | 20.64 | 9.37 | 21 | 144776 | 1167 | 50459160 |
Melaena | 20.60 | 9.37 | 28 | 144769 | 26836 | 50433491 |
Febrile neutropenia | 20.50 | 9.37 | 393 | 144404 | 97274 | 50363053 |
Eczema | 20.50 | 9.37 | 123 | 144674 | 22579 | 50437748 |
Eczema herpeticum | 20.46 | 9.37 | 9 | 144788 | 115 | 50460212 |
Disease progression | 20.24 | 9.37 | 176 | 144621 | 95690 | 50364637 |
Diaphragm muscle weakness | 20.19 | 9.37 | 6 | 144791 | 21 | 50460306 |
Tendon rupture | 19.88 | 9.37 | 55 | 144742 | 7089 | 50453238 |
Femur fracture | 19.85 | 9.37 | 49 | 144748 | 37415 | 50422912 |
Fistula | 19.72 | 9.37 | 60 | 144737 | 8158 | 50452169 |
Neuroleptic malignant syndrome | 19.55 | 9.37 | 4 | 144793 | 11126 | 50449201 |
Arteriosclerosis coronary artery | 19.51 | 9.37 | 57 | 144740 | 7579 | 50452748 |
Arthralgia | 19.36 | 9.37 | 1481 | 143316 | 437221 | 50023106 |
Anal abscess | 19.25 | 9.37 | 37 | 144760 | 3754 | 50456573 |
Meningitis candida | 19.24 | 9.37 | 7 | 144790 | 52 | 50460275 |
Skin weeping | 19.05 | 9.37 | 13 | 144784 | 411 | 50459916 |
Neutropenia | 18.73 | 9.37 | 304 | 144493 | 147661 | 50312666 |
Hepatic function abnormal | 18.72 | 9.37 | 41 | 144756 | 32640 | 50427687 |
White blood cell count decreased | 18.60 | 9.37 | 229 | 144568 | 116493 | 50343834 |
Dry eye | 18.60 | 9.37 | 40 | 144757 | 32055 | 50428272 |
Diabetes insipidus | 18.54 | 9.37 | 28 | 144769 | 2336 | 50457991 |
Multiple sclerosis relapse | 18.51 | 9.37 | 62 | 144735 | 42902 | 50417425 |
Loss of consciousness | 18.47 | 9.37 | 200 | 144597 | 104153 | 50356174 |
Drug level above therapeutic | 18.38 | 9.37 | 37 | 144760 | 3883 | 50456444 |
Hyperemesis gravidarum | 18.33 | 9.37 | 14 | 144783 | 529 | 50459798 |
Natural killer cell count decreased | 18.33 | 9.37 | 6 | 144791 | 31 | 50460296 |
Product quality issue | 18.27 | 9.37 | 38 | 144759 | 30820 | 50429507 |
Therapy cessation | 18.10 | 9.37 | 29 | 144768 | 25982 | 50434345 |
Labelled drug-drug interaction medication error | 17.92 | 9.37 | 4 | 144793 | 10473 | 50449854 |
B-lymphocyte count increased | 17.79 | 9.37 | 8 | 144789 | 108 | 50460219 |
Orthostatic hypotension | 17.71 | 9.37 | 36 | 144761 | 29445 | 50430882 |
Pituitary tumour recurrent | 17.70 | 9.37 | 7 | 144790 | 67 | 50460260 |
Enterococcal sepsis | 17.68 | 9.37 | 20 | 144777 | 1255 | 50459072 |
Osteonecrosis of jaw | 17.66 | 9.37 | 42 | 144755 | 32484 | 50427843 |
Unevaluable event | 17.52 | 9.37 | 70 | 144727 | 45996 | 50414331 |
X-ray abnormal | 17.47 | 9.37 | 29 | 144768 | 2623 | 50457704 |
Hepatotoxicity | 17.44 | 9.37 | 32 | 144765 | 27194 | 50433133 |
Leukoencephalopathy | 17.44 | 9.37 | 36 | 144761 | 3847 | 50456480 |
Acute myocardial infarction | 17.37 | 9.37 | 36 | 144761 | 29237 | 50431090 |
Dizziness | 17.36 | 9.37 | 812 | 143985 | 345557 | 50114770 |
Tremor | 17.36 | 9.37 | 228 | 144569 | 114675 | 50345652 |
Rhinovirus infection | 17.34 | 9.37 | 34 | 144763 | 3500 | 50456827 |
Drug specific antibody present | 17.26 | 9.37 | 33 | 144764 | 3335 | 50456992 |
Anti-cyclic citrullinated peptide antibody | 17.20 | 9.37 | 22 | 144775 | 1570 | 50458757 |
Vaginal flatulence | 17.02 | 9.37 | 10 | 144787 | 242 | 50460085 |
Cerebral microangiopathy | 16.94 | 9.37 | 10 | 144787 | 244 | 50460083 |
Septic shock | 16.76 | 9.37 | 243 | 144554 | 56932 | 50403395 |
Product storage error | 16.72 | 9.37 | 7 | 144790 | 12217 | 50448110 |
Neutropenic infection | 16.71 | 9.37 | 18 | 144779 | 1069 | 50459258 |
Mastocytosis | 16.69 | 9.37 | 13 | 144784 | 506 | 50459821 |
Dry skin | 16.64 | 9.37 | 193 | 144604 | 42998 | 50417329 |
Vertigo | 16.57 | 9.37 | 84 | 144713 | 51748 | 50408579 |
Tuberculosis gastrointestinal | 16.54 | 9.37 | 11 | 144786 | 333 | 50459994 |
Asthenia | 16.38 | 9.37 | 746 | 144051 | 318296 | 50142031 |
Skin fragility | 16.30 | 9.37 | 13 | 144784 | 524 | 50459803 |
Salpingo-oophorectomy unilateral | 16.21 | 9.37 | 13 | 144784 | 528 | 50459799 |
Gastrointestinal disorder | 16.20 | 9.37 | 369 | 144428 | 94087 | 50366240 |
Stomatitis | 16.19 | 9.37 | 392 | 144405 | 100952 | 50359375 |
Excessive skin | 16.09 | 9.37 | 8 | 144789 | 137 | 50460190 |
Increased bronchial secretion | 15.96 | 9.37 | 21 | 144776 | 1541 | 50458786 |
Hypogonadism | 15.94 | 9.37 | 7 | 144790 | 89 | 50460238 |
Rhabdomyolysis | 15.68 | 9.37 | 58 | 144739 | 38969 | 50421358 |
Abdominal pain | 15.63 | 9.37 | 826 | 143971 | 235402 | 50224925 |
Leukopenia | 15.61 | 9.37 | 121 | 144676 | 67407 | 50392920 |
Secondary hypogonadism | 15.34 | 9.37 | 7 | 144790 | 98 | 50460229 |
Adverse event | 15.30 | 9.37 | 192 | 144605 | 43571 | 50416756 |
Abortion spontaneous | 14.94 | 9.37 | 65 | 144732 | 41707 | 50418620 |
Product prescribing error | 14.94 | 9.37 | 23 | 144774 | 20938 | 50439389 |
Complication associated with device | 14.92 | 9.37 | 12 | 144785 | 14643 | 50445684 |
PO2 decreased | 14.79 | 9.37 | 19 | 144778 | 1362 | 50458965 |
Liver function test abnormal | 14.67 | 9.37 | 71 | 144726 | 44268 | 50416059 |
Faecal calprotectin abnormal | 14.60 | 9.37 | 6 | 144791 | 64 | 50460263 |
Lupus vulgaris | 14.59 | 9.37 | 13 | 144784 | 611 | 50459716 |
Fluid retention | 14.58 | 9.37 | 85 | 144712 | 50564 | 50409763 |
CSF lymphocyte count abnormal | 14.58 | 9.37 | 3 | 144794 | 0 | 50460327 |
Hepatitis | 14.52 | 9.37 | 44 | 144753 | 31409 | 50428918 |
Cerebral vasoconstriction | 14.51 | 9.37 | 16 | 144781 | 976 | 50459351 |
Prescribed overdose | 14.41 | 9.37 | 81 | 144716 | 14519 | 50445808 |
Accidental overdose | 14.34 | 9.37 | 21 | 144776 | 19512 | 50440815 |
Dislocation of vertebra | 14.31 | 9.37 | 29 | 144768 | 3058 | 50457269 |
Medication error | 14.28 | 9.37 | 54 | 144743 | 36050 | 50424277 |
Hypernatraemia | 14.11 | 9.37 | 45 | 144752 | 6276 | 50454051 |
Depression | 14.04 | 9.37 | 363 | 144434 | 165060 | 50295267 |
Diarrhoea haemorrhagic | 13.94 | 9.37 | 51 | 144746 | 7624 | 50452703 |
Fibromyalgia | 13.92 | 9.37 | 193 | 144604 | 44785 | 50415542 |
Pneumatosis intestinalis | 13.86 | 9.37 | 23 | 144774 | 2080 | 50458247 |
Hepatic cirrhosis | 13.80 | 9.37 | 18 | 144779 | 17559 | 50442768 |
Injection site pruritus | 13.78 | 9.37 | 64 | 144733 | 40347 | 50419980 |
Cardiac arrest | 13.75 | 9.37 | 163 | 144634 | 83488 | 50376839 |
Adjustment disorder with depressed mood | 13.72 | 9.37 | 27 | 144770 | 2787 | 50457540 |
Thrombocytopenia | 13.41 | 9.37 | 271 | 144526 | 127402 | 50332925 |
Pseudomonas infection | 13.37 | 9.37 | 58 | 144739 | 9372 | 50450955 |
Myoclonus | 13.35 | 9.37 | 13 | 144784 | 14457 | 50445870 |
Vaginal discharge | 13.28 | 9.37 | 39 | 144758 | 5201 | 50455126 |
Hypercapnia | 13.25 | 9.37 | 36 | 144761 | 4591 | 50455736 |
Pseudostroke | 13.25 | 9.37 | 4 | 144793 | 15 | 50460312 |
Skin ulcer | 13.22 | 9.37 | 54 | 144743 | 35264 | 50425063 |
Status asthmaticus | 13.17 | 9.37 | 14 | 144783 | 819 | 50459508 |
Hypertensive crisis | 13.11 | 9.37 | 11 | 144786 | 13143 | 50447184 |
Creatinine renal clearance decreased | 13.04 | 9.37 | 9 | 144788 | 11872 | 50448455 |
Device difficult to use | 12.99 | 9.37 | 6 | 144791 | 9880 | 50450447 |
Aspergillus infection | 12.96 | 9.37 | 46 | 144751 | 6775 | 50453552 |
Lung hyperinflation | 12.96 | 9.37 | 16 | 144781 | 1102 | 50459225 |
Aborted pregnancy | 12.91 | 9.37 | 5 | 144792 | 45 | 50460282 |
Pulmonary arterial hypertension | 12.91 | 9.37 | 24 | 144773 | 20295 | 50440032 |
Tendon disorder | 12.91 | 9.37 | 39 | 144758 | 5283 | 50455044 |
Coronary artery dissection | 12.90 | 9.37 | 13 | 144784 | 714 | 50459613 |
Skin injury | 12.86 | 9.37 | 19 | 144778 | 1555 | 50458772 |
Bronchitis | 12.85 | 9.37 | 215 | 144582 | 103944 | 50356383 |
Bacterial infection | 12.71 | 9.37 | 85 | 144712 | 16196 | 50444131 |
PCO2 increased | 12.67 | 9.37 | 16 | 144781 | 1127 | 50459200 |
Shared psychotic disorder | 12.67 | 9.37 | 4 | 144793 | 18 | 50460309 |
Myelosuppression | 12.64 | 9.37 | 12 | 144785 | 13505 | 50446822 |
Hyperhidrosis | 12.58 | 9.37 | 180 | 144617 | 89246 | 50371081 |
Brachycephaly | 12.50 | 9.37 | 4 | 144793 | 19 | 50460308 |
Akathisia | 12.46 | 9.37 | 4 | 144793 | 8225 | 50452102 |
Gastrointestinal scarring | 12.45 | 9.37 | 8 | 144789 | 228 | 50460099 |
Ankle fracture | 12.45 | 9.37 | 16 | 144781 | 15706 | 50444621 |
Abnormal faeces | 12.37 | 9.37 | 33 | 144764 | 4163 | 50456164 |
Device dislocation | 12.36 | 9.37 | 27 | 144770 | 21519 | 50438808 |
Schizophrenia | 12.31 | 9.37 | 3 | 144794 | 7394 | 50452933 |
Autoimmune nephritis | 12.29 | 9.37 | 9 | 144788 | 319 | 50460008 |
Injection site rash | 12.26 | 9.37 | 17 | 144780 | 16160 | 50444167 |
Hypoperfusion | 12.25 | 9.37 | 17 | 144780 | 1313 | 50459014 |
Transient ischaemic attack | 12.21 | 9.37 | 49 | 144748 | 32161 | 50428166 |
Parkinsonism | 12.21 | 9.37 | 5 | 144792 | 8842 | 50451485 |
Agitation | 12.17 | 9.37 | 96 | 144701 | 53288 | 50407039 |
Pneumatosis | 12.16 | 9.37 | 10 | 144787 | 421 | 50459906 |
Herpes simplex hepatitis | 12.16 | 9.37 | 9 | 144788 | 324 | 50460003 |
Glucocorticoid deficiency | 12.15 | 9.37 | 8 | 144789 | 238 | 50460089 |
Dyskinesia | 12.14 | 9.37 | 40 | 144757 | 27821 | 50432506 |
Breast cancer stage III | 12.13 | 9.37 | 28 | 144769 | 3228 | 50457099 |
Anorectal ulcer | 12.11 | 9.37 | 5 | 144792 | 54 | 50460273 |
Ascites | 12.11 | 9.37 | 57 | 144740 | 35804 | 50424523 |
Blood corticotrophin decreased | 12.06 | 9.37 | 8 | 144789 | 241 | 50460086 |
Optic glioma | 12.05 | 9.37 | 3 | 144794 | 4 | 50460323 |
Blood growth hormone increased | 12.04 | 9.37 | 10 | 144787 | 427 | 50459900 |
Cerebrospinal fluid leakage | 11.88 | 9.37 | 14 | 144783 | 918 | 50459409 |
Non-consummation | 11.87 | 9.37 | 5 | 144792 | 57 | 50460270 |
Bronchopulmonary aspergillosis | 11.78 | 9.37 | 48 | 144749 | 7544 | 50452783 |
Herpes simplex | 11.69 | 9.37 | 46 | 144751 | 7116 | 50453211 |
Palmar-plantar erythrodysaesthesia syndrome | 11.69 | 9.37 | 25 | 144772 | 20073 | 50440254 |
Drug eruption | 11.64 | 9.37 | 32 | 144765 | 23574 | 50436753 |
Blood parathyroid hormone decreased | 11.61 | 9.37 | 3 | 144794 | 7111 | 50453216 |
Eosinophilic oesophagitis | 11.61 | 9.37 | 8 | 144789 | 257 | 50460070 |
Renal failure | 11.60 | 9.37 | 225 | 144572 | 106408 | 50353919 |
Enterobacter infection | 11.58 | 9.37 | 20 | 144777 | 1868 | 50458459 |
Extrapyramidal disorder | 11.54 | 9.37 | 10 | 144787 | 11760 | 50448567 |
Enteritis | 11.48 | 9.37 | 45 | 144752 | 6950 | 50453377 |
Musculoskeletal disorder | 11.46 | 9.37 | 20 | 144777 | 17329 | 50442998 |
Nasopharyngitis | 11.46 | 9.37 | 668 | 144129 | 192259 | 50268068 |
Musculoskeletal stiffness | 11.45 | 9.37 | 463 | 144334 | 128018 | 50332309 |
Coronary artery disease | 11.41 | 9.37 | 45 | 144752 | 29681 | 50430646 |
Geotrichum infection | 11.41 | 9.37 | 10 | 144787 | 460 | 50459867 |
Contusion | 11.36 | 9.37 | 410 | 144387 | 111773 | 50348554 |
Loss of employment | 11.34 | 9.37 | 18 | 144779 | 1568 | 50458759 |
Pyoderma gangrenosum | 11.28 | 9.37 | 25 | 144772 | 2806 | 50457521 |
Product use in unapproved indication | 11.18 | 9.37 | 421 | 144376 | 115398 | 50344929 |
Autoimmune disorder | 11.16 | 9.37 | 40 | 144757 | 5920 | 50454407 |
Rheumatoid nodule | 11.11 | 9.37 | 12 | 144785 | 12723 | 50447604 |
Ocular procedural complication | 11.11 | 9.37 | 9 | 144788 | 371 | 50459956 |
International normalised ratio increased | 11.09 | 9.37 | 75 | 144722 | 43077 | 50417250 |
Insomnia | 11.07 | 9.37 | 399 | 144398 | 174466 | 50285861 |
Sinusitis fungal | 11.01 | 9.37 | 16 | 144781 | 1290 | 50459037 |
Astrocytoma | 10.96 | 9.37 | 5 | 144792 | 70 | 50460257 |
Osteopenia | 10.90 | 9.37 | 20 | 144777 | 16998 | 50443329 |
Metastases to liver | 10.88 | 9.37 | 26 | 144771 | 20078 | 50440249 |
Visual pathway disorder | 10.85 | 9.37 | 4 | 144793 | 31 | 50460296 |
Crohn's disease | 10.84 | 9.37 | 34 | 144763 | 4699 | 50455628 |
Respiratory depression | 10.84 | 9.37 | 11 | 144786 | 11999 | 50448328 |
Erythema nodosum | 10.81 | 9.37 | 30 | 144767 | 3873 | 50456454 |
Chronic kidney disease | 10.79 | 9.37 | 68 | 144729 | 39703 | 50420624 |
Pleural effusion | 10.75 | 9.37 | 166 | 144631 | 81288 | 50379039 |
Drug resistance | 10.73 | 9.37 | 24 | 144773 | 18965 | 50441362 |
Dystonia | 10.67 | 9.37 | 11 | 144786 | 11915 | 50448412 |
Heart rate decreased | 10.65 | 9.37 | 155 | 144642 | 36342 | 50423985 |
Rectal abscess | 10.64 | 9.37 | 14 | 144783 | 1028 | 50459299 |
Aplastic anaemia | 10.63 | 9.37 | 47 | 144750 | 7656 | 50452671 |
Lip dry | 10.61 | 9.37 | 34 | 144763 | 4753 | 50455574 |
Therapeutic reaction time decreased | 10.59 | 9.37 | 16 | 144781 | 1336 | 50458991 |
Feeding intolerance | 10.56 | 9.37 | 10 | 144787 | 509 | 50459818 |
Basal cell carcinoma | 10.55 | 9.37 | 33 | 144764 | 23323 | 50437004 |
Pituitary infarction | 10.53 | 9.37 | 4 | 144793 | 34 | 50460293 |
Toxic skin eruption | 10.50 | 9.37 | 10 | 144787 | 11241 | 50449086 |
Herpes zoster | 10.49 | 9.37 | 141 | 144656 | 70645 | 50389682 |
Uterine cyst | 10.47 | 9.37 | 9 | 144788 | 403 | 50459924 |
Mydriasis | 10.45 | 9.37 | 9 | 144788 | 10618 | 50449709 |
Plasma cell myeloma | 10.45 | 9.37 | 50 | 144747 | 31272 | 50429055 |
Prescription drug used without a prescription | 10.42 | 9.37 | 18 | 144779 | 1682 | 50458645 |
Arrhythmia | 10.42 | 9.37 | 54 | 144743 | 33078 | 50427249 |
Myelodysplastic syndrome | 10.41 | 9.37 | 17 | 144780 | 15115 | 50445212 |
Anticipatory anxiety | 10.37 | 9.37 | 8 | 144789 | 307 | 50460020 |
Oesophageal adenocarcinoma recurrent | 10.33 | 9.37 | 4 | 144793 | 36 | 50460291 |
Exposure during pregnancy | 10.31 | 9.37 | 434 | 144363 | 120581 | 50339746 |
Staphylococcal infection | 10.29 | 9.37 | 151 | 144646 | 35465 | 50424862 |
Antithrombin III decreased | 10.26 | 9.37 | 7 | 144790 | 221 | 50460106 |
Colonic abscess | 10.24 | 9.37 | 12 | 144785 | 782 | 50459545 |
Subacute combined cord degeneration | 10.24 | 9.37 | 7 | 144790 | 222 | 50460105 |
Weaning failure | 10.21 | 9.37 | 8 | 144789 | 314 | 50460013 |
Bone erosion | 10.21 | 9.37 | 11 | 144786 | 11676 | 50448651 |
Therapy interrupted | 10.18 | 9.37 | 27 | 144770 | 20125 | 50440202 |
Thyroglossal cyst infection | 10.14 | 9.37 | 4 | 144793 | 38 | 50460289 |
Pituitary haemorrhage | 10.14 | 9.37 | 5 | 144792 | 84 | 50460243 |
Respiratory acidosis | 10.07 | 9.37 | 39 | 144758 | 5989 | 50454338 |
Metastases to lung | 10.05 | 9.37 | 10 | 144787 | 11010 | 50449317 |
Tuberous sclerosis complex | 10.04 | 9.37 | 5 | 144792 | 86 | 50460241 |
Encephalitis autoimmune | 10.01 | 9.37 | 15 | 144782 | 1243 | 50459084 |
Pneumopericardium | 9.87 | 9.37 | 4 | 144793 | 41 | 50460286 |
Toothache | 9.83 | 9.37 | 21 | 144776 | 16873 | 50443454 |
Blood gonadotrophin decreased | 9.78 | 9.37 | 3 | 144794 | 12 | 50460315 |
Renal disorder | 9.71 | 9.37 | 43 | 144754 | 27462 | 50432865 |
Choriocarcinoma | 9.71 | 9.37 | 4 | 144793 | 43 | 50460284 |
Genital rash | 9.70 | 9.37 | 9 | 144788 | 446 | 50459881 |
Feeling abnormal | 9.70 | 9.37 | 279 | 144518 | 125213 | 50335114 |
Haematuria | 9.69 | 9.37 | 39 | 144758 | 25574 | 50434753 |
Pulmonary hypertension | 9.66 | 9.37 | 56 | 144741 | 33361 | 50426966 |
Underdose | 9.62 | 9.37 | 28 | 144769 | 20250 | 50440077 |
Liver injury | 9.62 | 9.37 | 111 | 144686 | 24695 | 50435632 |
Dysarthria | 9.62 | 9.37 | 65 | 144732 | 37338 | 50422989 |
Epistaxis | 9.62 | 9.37 | 127 | 144670 | 63827 | 50396500 |
Blood smear test abnormal | 9.54 | 9.37 | 5 | 144792 | 96 | 50460231 |
Steroid dependence | 9.53 | 9.37 | 8 | 144789 | 347 | 50459980 |
Muscle spasticity | 9.48 | 9.37 | 22 | 144775 | 17162 | 50443165 |
Injection site bruising | 9.40 | 9.37 | 64 | 144733 | 36704 | 50423623 |
Endocarditis bacterial | 9.39 | 9.37 | 10 | 144787 | 586 | 50459741 |
Vaccination site inflammation | 9.39 | 9.37 | 4 | 144793 | 47 | 50460280 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Blood pressure fluctuation | 190.82 | 9.93 | 244 | 74937 | 19650 | 29479696 |
Adrenal insufficiency | 181.72 | 9.93 | 180 | 75001 | 10934 | 29488412 |
Completed suicide | 173.81 | 9.93 | 15 | 75166 | 90231 | 29409115 |
Drug abuse | 166.27 | 9.93 | 9 | 75172 | 79874 | 29419472 |
Craniopharyngioma | 165.31 | 9.93 | 51 | 75130 | 242 | 29499104 |
Toxicity to various agents | 159.41 | 9.93 | 125 | 75056 | 173536 | 29325810 |
Infusion related reaction | 154.16 | 9.93 | 343 | 74838 | 43543 | 29455803 |
Adrenocortical insufficiency acute | 149.08 | 9.93 | 71 | 75110 | 1249 | 29498097 |
Death | 140.93 | 9.93 | 426 | 74755 | 341658 | 29157688 |
Graft loss | 138.43 | 9.93 | 59 | 75122 | 789 | 29498557 |
Off label use | 133.58 | 9.93 | 1256 | 73925 | 299544 | 29199802 |
Intentional product use issue | 132.56 | 9.93 | 317 | 74864 | 42181 | 29457165 |
Colitis ulcerative | 121.46 | 9.93 | 156 | 75025 | 12613 | 29486733 |
Febrile bone marrow aplasia | 120.06 | 9.93 | 119 | 75062 | 7232 | 29492114 |
Serum sickness | 118.65 | 9.93 | 67 | 75114 | 1698 | 29497648 |
Hypofibrinogenaemia | 98.26 | 9.93 | 56 | 75125 | 1445 | 29497901 |
Frequent bowel movements | 94.42 | 9.93 | 117 | 75064 | 9122 | 29490224 |
Febrile neutropenia | 91.53 | 9.93 | 542 | 74639 | 111698 | 29387648 |
Inappropriate schedule of product administration | 75.67 | 9.93 | 267 | 74914 | 44205 | 29455141 |
Product use issue | 75.12 | 9.93 | 294 | 74887 | 51150 | 29448196 |
Leukoencephalopathy | 74.90 | 9.93 | 68 | 75113 | 3699 | 29495647 |
Condition aggravated | 73.89 | 9.93 | 629 | 74552 | 145666 | 29353680 |
Diabetes insipidus | 73.56 | 9.93 | 56 | 75125 | 2378 | 29496968 |
Hypopituitarism | 73.54 | 9.93 | 49 | 75132 | 1681 | 29497665 |
Intentional overdose | 67.51 | 9.93 | 9 | 75172 | 38519 | 29460827 |
Heart rate irregular | 67.07 | 9.93 | 120 | 75061 | 12997 | 29486349 |
Adrenal suppression | 64.34 | 9.93 | 30 | 75151 | 502 | 29498844 |
Steroid withdrawal syndrome | 58.68 | 9.93 | 22 | 75159 | 205 | 29499141 |
Drug interaction | 56.44 | 9.93 | 284 | 74897 | 197101 | 29302245 |
Aplastic anaemia | 55.18 | 9.93 | 81 | 75100 | 7429 | 29491917 |
Pituitary tumour benign | 53.27 | 9.93 | 30 | 75151 | 756 | 29498590 |
Heart rate decreased | 52.62 | 9.93 | 161 | 75020 | 24751 | 29474595 |
Mucosal inflammation | 50.59 | 9.93 | 186 | 74995 | 31409 | 29467937 |
Interstitial lung disease | 49.80 | 9.93 | 44 | 75137 | 57674 | 29441672 |
Impaired quality of life | 49.58 | 9.93 | 46 | 75135 | 2573 | 29496773 |
Drug specific antibody present | 48.52 | 9.93 | 45 | 75136 | 2516 | 29496830 |
Septic shock | 48.30 | 9.93 | 298 | 74883 | 62262 | 29437084 |
Insulin-like growth factor decreased | 48.20 | 9.93 | 20 | 75161 | 249 | 29499097 |
Faecal calprotectin increased | 47.36 | 9.93 | 36 | 75145 | 1525 | 29497821 |
Tendon pain | 45.58 | 9.93 | 43 | 75138 | 2457 | 29496889 |
Body temperature fluctuation | 45.23 | 9.93 | 34 | 75147 | 1416 | 29497930 |
Pseudostroke | 43.19 | 9.93 | 12 | 75169 | 36 | 29499310 |
Hypertriglyceridaemia | 42.93 | 9.93 | 72 | 75109 | 7403 | 29491943 |
Overdose | 42.32 | 9.93 | 87 | 75094 | 79732 | 29419614 |
Tendon rupture | 42.13 | 9.93 | 65 | 75116 | 6230 | 29493116 |
Drug level below therapeutic | 40.32 | 9.93 | 52 | 75129 | 4219 | 29495127 |
Tendon disorder | 40.25 | 9.93 | 40 | 75141 | 2438 | 29496908 |
Fistula | 40.05 | 9.93 | 57 | 75124 | 5082 | 29494264 |
Suicide attempt | 38.90 | 9.93 | 19 | 75162 | 34091 | 29465255 |
Neoplasm recurrence | 37.96 | 9.93 | 35 | 75146 | 1942 | 29497404 |
Insulin-like growth factor increased | 36.78 | 9.93 | 27 | 75154 | 1084 | 29498262 |
Colitis | 36.58 | 9.93 | 167 | 75014 | 31081 | 29468265 |
Hypophysitis | 36.14 | 9.93 | 34 | 75147 | 1936 | 29497410 |
Fall | 36.08 | 9.93 | 283 | 74898 | 176895 | 29322451 |
Myocardial infarction | 36.04 | 9.93 | 151 | 75030 | 110145 | 29389201 |
Bronchiectasis | 34.63 | 9.93 | 61 | 75120 | 6524 | 29492822 |
Cortisol decreased | 34.03 | 9.93 | 23 | 75158 | 808 | 29498538 |
Flushing | 33.97 | 9.93 | 155 | 75026 | 28837 | 29470509 |
Therapeutic response shortened | 32.80 | 9.93 | 50 | 75131 | 4741 | 29494605 |
Pelvic abscess | 32.51 | 9.93 | 23 | 75158 | 871 | 29498475 |
Myelopathy | 32.31 | 9.93 | 32 | 75149 | 1942 | 29497404 |
Arthralgia | 31.07 | 9.93 | 513 | 74668 | 139104 | 29360242 |
Crohn's disease | 30.57 | 9.93 | 38 | 75143 | 2971 | 29496375 |
Hypertrophic cardiomyopathy | 30.55 | 9.93 | 22 | 75159 | 857 | 29498489 |
Epiphysiolysis | 30.17 | 9.93 | 11 | 75170 | 94 | 29499252 |
Lichen planus | 29.16 | 9.93 | 21 | 75160 | 818 | 29498528 |
Meningitis candida | 29.04 | 9.93 | 10 | 75171 | 71 | 29499275 |
Chorioretinopathy | 29.01 | 9.93 | 26 | 75155 | 1390 | 29497956 |
Sedation | 28.35 | 9.93 | 5 | 75176 | 17400 | 29481946 |
Cardiac failure | 27.50 | 9.93 | 106 | 75075 | 79181 | 29420165 |
Acute kidney injury | 27.46 | 9.93 | 492 | 74689 | 264775 | 29234571 |
Drug hypersensitivity | 27.35 | 9.93 | 280 | 74901 | 68126 | 29431220 |
Pneumoretroperitoneum | 27.14 | 9.93 | 9 | 75172 | 56 | 29499290 |
Pituitary haemorrhage | 26.98 | 9.93 | 12 | 75169 | 179 | 29499167 |
Renal impairment | 26.77 | 9.93 | 111 | 75070 | 81222 | 29418124 |
Thermophobia | 26.75 | 9.93 | 9 | 75172 | 59 | 29499287 |
Stevens-Johnson syndrome | 26.30 | 9.93 | 97 | 75084 | 16400 | 29482946 |
Growth retardation | 25.82 | 9.93 | 26 | 75155 | 1610 | 29497736 |
Anaemia | 25.36 | 9.93 | 359 | 74822 | 200592 | 29298754 |
Atrial fibrillation | 25.26 | 9.93 | 161 | 75020 | 105485 | 29393861 |
Perioral dermatitis | 25.04 | 9.93 | 10 | 75171 | 112 | 29499234 |
Soft tissue mass | 24.62 | 9.93 | 17 | 75164 | 619 | 29498727 |
Blood pressure increased | 24.42 | 9.93 | 291 | 74890 | 73512 | 29425834 |
Candida infection | 23.83 | 9.93 | 89 | 75092 | 15136 | 29484210 |
Thyroxine free decreased | 23.63 | 9.93 | 12 | 75169 | 244 | 29499102 |
Gastrointestinal haemorrhage | 23.49 | 9.93 | 113 | 75068 | 79420 | 29419926 |
Adrenocorticotropic hormone deficiency | 23.09 | 9.93 | 16 | 75165 | 586 | 29498760 |
Poor venous access | 23.09 | 9.93 | 34 | 75147 | 3127 | 29496219 |
Shared psychotic disorder | 22.98 | 9.93 | 6 | 75175 | 13 | 29499333 |
Rash erythematous | 22.16 | 9.93 | 111 | 75070 | 21451 | 29477895 |
Cardio-respiratory arrest | 22.15 | 9.93 | 61 | 75120 | 50540 | 29448806 |
Oesophageal perforation | 22.00 | 9.93 | 17 | 75164 | 738 | 29498608 |
Symptom masked | 21.92 | 9.93 | 15 | 75166 | 538 | 29498808 |
Multimorbidity | 21.87 | 9.93 | 15 | 75166 | 540 | 29498806 |
Posterior reversible encephalopathy syndrome | 21.81 | 9.93 | 61 | 75120 | 8915 | 29490431 |
Periorbital infection | 21.41 | 9.93 | 9 | 75172 | 116 | 29499230 |
Cholangitis infective | 21.38 | 9.93 | 11 | 75170 | 230 | 29499116 |
Musculoskeletal injury | 21.27 | 9.93 | 9 | 75172 | 118 | 29499228 |
Erythema | 21.14 | 9.93 | 289 | 74892 | 75317 | 29424029 |
Anal fistula | 20.96 | 9.93 | 38 | 75143 | 4157 | 29495189 |
Klebsiella infection | 20.96 | 9.93 | 53 | 75128 | 7296 | 29492050 |
Subdural haematoma | 20.94 | 9.93 | 10 | 75171 | 18183 | 29481163 |
Hyperbilirubinaemia | 20.69 | 9.93 | 84 | 75097 | 14850 | 29484496 |
Optic nerve disorder | 20.64 | 9.93 | 15 | 75166 | 593 | 29498753 |
Hypogonadism | 20.24 | 9.93 | 22 | 75159 | 1489 | 29497857 |
Blood growth hormone decreased | 20.07 | 9.93 | 6 | 75175 | 25 | 29499321 |
Neuroleptic malignant syndrome | 19.97 | 9.93 | 8 | 75173 | 16140 | 29483206 |
Feeling cold | 19.96 | 9.93 | 60 | 75121 | 9131 | 29490215 |
Intentional product misuse | 19.91 | 9.93 | 36 | 75145 | 34625 | 29464721 |
Drug level decreased | 19.89 | 9.93 | 47 | 75134 | 6200 | 29493146 |
Abdominal pain | 19.83 | 9.93 | 467 | 74714 | 134890 | 29364456 |
Anaphylactic reaction | 19.81 | 9.93 | 129 | 75052 | 27444 | 29471902 |
Angina pectoris | 19.79 | 9.93 | 25 | 75156 | 27825 | 29471521 |
Neurotoxicity | 19.30 | 9.93 | 81 | 75100 | 14532 | 29484814 |
Bronchial haemorrhage | 19.08 | 9.93 | 15 | 75166 | 668 | 29498678 |
Pituitary tumour recurrent | 19.08 | 9.93 | 7 | 75174 | 61 | 29499285 |
Astrocytoma | 18.76 | 9.93 | 9 | 75172 | 161 | 29499185 |
Idiopathic intracranial hypertension | 18.67 | 9.93 | 14 | 75167 | 581 | 29498765 |
Vestibular neuronitis | 18.56 | 9.93 | 9 | 75172 | 165 | 29499181 |
Superinfection | 18.32 | 9.93 | 24 | 75157 | 1977 | 29497369 |
Pouchitis | 18.30 | 9.93 | 14 | 75167 | 599 | 29498747 |
Pituitary tumour | 18.20 | 9.93 | 13 | 75168 | 500 | 29498846 |
Chills | 18.12 | 9.93 | 268 | 74913 | 71032 | 29428314 |
Meningitis tuberculous | 18.06 | 9.93 | 14 | 75167 | 611 | 29498735 |
Syncope | 17.94 | 9.93 | 127 | 75054 | 81244 | 29418102 |
Cushingoid | 17.48 | 9.93 | 26 | 75155 | 2412 | 29496934 |
Gastrointestinal inflammation | 17.31 | 9.93 | 29 | 75152 | 2979 | 29496367 |
Anal abscess | 17.25 | 9.93 | 40 | 75141 | 5211 | 29494135 |
Gastrointestinal anastomotic leak | 17.24 | 9.93 | 11 | 75170 | 350 | 29498996 |
Clostridium difficile infection | 17.23 | 9.93 | 84 | 75097 | 16057 | 29483289 |
Blood thyroid stimulating hormone decreased | 17.14 | 9.93 | 22 | 75159 | 1776 | 29497570 |
Splenic peliosis | 17.09 | 9.93 | 5 | 75176 | 19 | 29499327 |
Blood creatine phosphokinase increased | 17.05 | 9.93 | 50 | 75131 | 40594 | 29458752 |
Cryptococcal fungaemia | 16.95 | 9.93 | 7 | 75174 | 86 | 29499260 |
Coma | 16.94 | 9.93 | 48 | 75133 | 39402 | 29459944 |
Hospitalisation | 16.91 | 9.93 | 60 | 75121 | 45928 | 29453418 |
Blood growth hormone increased | 16.88 | 9.93 | 10 | 75171 | 278 | 29499068 |
Hallucination | 16.66 | 9.93 | 58 | 75123 | 44654 | 29454692 |
Posturing | 16.59 | 9.93 | 12 | 75169 | 471 | 29498875 |
Pyrexia | 16.49 | 9.93 | 891 | 74290 | 286731 | 29212615 |
Glioma | 16.47 | 9.93 | 10 | 75171 | 291 | 29499055 |
Diarrhoea haemorrhagic | 16.37 | 9.93 | 42 | 75139 | 5832 | 29493514 |
Secondary adrenocortical insufficiency | 16.34 | 9.93 | 17 | 75164 | 1094 | 29498252 |
Aggression | 16.19 | 9.93 | 42 | 75139 | 35499 | 29463847 |
Cerebrospinal fluid leakage | 16.04 | 9.93 | 11 | 75170 | 396 | 29498950 |
Lacrimal duct neoplasm | 15.99 | 9.93 | 5 | 75176 | 25 | 29499321 |
Mantle cell lymphoma stage III | 15.99 | 9.93 | 5 | 75176 | 25 | 29499321 |
Anal inflammation | 15.90 | 9.93 | 10 | 75171 | 310 | 29499036 |
Body height below normal | 15.90 | 9.93 | 9 | 75172 | 229 | 29499117 |
Extrapyramidal disorder | 15.82 | 9.93 | 4 | 75177 | 10827 | 29488519 |
Clostridium test positive | 15.79 | 9.93 | 23 | 75158 | 2094 | 29497252 |
Gingival disorder | 15.75 | 9.93 | 18 | 75163 | 1288 | 29498058 |
Intentional self-injury | 15.70 | 9.93 | 6 | 75175 | 12455 | 29486891 |
Anaplastic astrocytoma | 15.29 | 9.93 | 7 | 75174 | 112 | 29499234 |
Lactic acidosis | 15.16 | 9.93 | 34 | 75147 | 30213 | 29469133 |
Thyroxine decreased | 15.13 | 9.93 | 7 | 75174 | 115 | 29499231 |
Glioblastoma multiforme | 15.01 | 9.93 | 13 | 75168 | 664 | 29498682 |
Dermatitis diaper | 14.94 | 9.93 | 9 | 75172 | 258 | 29499088 |
Renal failure | 14.89 | 9.93 | 212 | 74969 | 118387 | 29380959 |
Electrocardiogram QT prolonged | 14.76 | 9.93 | 45 | 75136 | 36092 | 29463254 |
Anal fissure | 14.75 | 9.93 | 26 | 75155 | 2782 | 29496564 |
Feeling hot | 14.71 | 9.93 | 78 | 75103 | 15410 | 29483936 |
Cryptococcal meningoencephalitis | 14.70 | 9.93 | 7 | 75174 | 123 | 29499223 |
Otitis media acute | 14.64 | 9.93 | 11 | 75170 | 458 | 29498888 |
Lichenification | 14.61 | 9.93 | 9 | 75172 | 269 | 29499077 |
Congenital cardiovascular anomaly | 14.59 | 9.93 | 8 | 75173 | 191 | 29499155 |
Functional gastrointestinal disorder | 14.57 | 9.93 | 22 | 75159 | 2068 | 29497278 |
Blood pressure diastolic decreased | 14.46 | 9.93 | 45 | 75136 | 6977 | 29492369 |
Respiratory disorder | 14.44 | 9.93 | 83 | 75098 | 16900 | 29482446 |
Addison's disease | 14.40 | 9.93 | 4 | 75177 | 12 | 29499334 |
Toxic epidermal necrolysis | 14.32 | 9.93 | 87 | 75094 | 18066 | 29481280 |
Nervous system disorder | 14.28 | 9.93 | 67 | 75114 | 12607 | 29486739 |
Eczema herpeticum | 14.21 | 9.93 | 7 | 75174 | 133 | 29499213 |
Perirectal abscess | 14.09 | 9.93 | 18 | 75163 | 1447 | 29497899 |
Sepsis | 14.06 | 9.93 | 468 | 74713 | 142214 | 29357132 |
Accidental exposure to product | 13.85 | 9.93 | 5 | 75176 | 10748 | 29488598 |
Product quality issue | 13.84 | 9.93 | 12 | 75169 | 15883 | 29483463 |
Short-bowel syndrome | 13.81 | 9.93 | 8 | 75173 | 213 | 29499133 |
Mean cell volume decreased | 13.73 | 9.93 | 16 | 75165 | 1169 | 29498177 |
Prothrombin level abnormal | 13.70 | 9.93 | 6 | 75175 | 86 | 29499260 |
Oxygen saturation abnormal | 13.66 | 9.93 | 16 | 75165 | 1176 | 29498170 |
Trichosporon infection | 13.61 | 9.93 | 12 | 75169 | 628 | 29498718 |
Transient ischaemic attack | 13.51 | 9.93 | 24 | 75157 | 23246 | 29476100 |
Coronary artery disease | 13.50 | 9.93 | 62 | 75119 | 44128 | 29455218 |
Cardiac failure congestive | 13.46 | 9.93 | 127 | 75054 | 76454 | 29422892 |
Hyperkalaemia | 13.44 | 9.93 | 96 | 75085 | 61296 | 29438050 |
Perineal pain | 13.40 | 9.93 | 13 | 75168 | 769 | 29498577 |
Accidental overdose | 13.34 | 9.93 | 15 | 75166 | 17578 | 29481768 |
Respiratory depression | 13.32 | 9.93 | 9 | 75172 | 13514 | 29485832 |
Transient aphasia | 13.22 | 9.93 | 6 | 75175 | 94 | 29499252 |
Malignant neoplasm progression | 13.19 | 9.93 | 122 | 75059 | 73737 | 29425609 |
Pallor | 13.10 | 9.93 | 95 | 75086 | 20929 | 29478417 |
Rectal abscess | 12.97 | 9.93 | 14 | 75167 | 940 | 29498406 |
Weight increased | 12.94 | 9.93 | 270 | 74911 | 76397 | 29422949 |
Strongyloidiasis | 12.92 | 9.93 | 22 | 75159 | 2290 | 29497056 |
Administration site bruise | 12.86 | 9.93 | 3 | 75178 | 3 | 29499343 |
General physical health deterioration | 12.86 | 9.93 | 184 | 74997 | 102673 | 29396673 |
Shunt malfunction | 12.85 | 9.93 | 7 | 75174 | 165 | 29499181 |
Contraindicated product prescribed | 12.76 | 9.93 | 9 | 75172 | 339 | 29499007 |
Gram stain positive | 12.73 | 9.93 | 6 | 75175 | 103 | 29499243 |
Phaeochromocytoma crisis | 12.44 | 9.93 | 5 | 75176 | 57 | 29499289 |
Morganella infection | 12.42 | 9.93 | 10 | 75171 | 461 | 29498885 |
Groin infection | 12.41 | 9.93 | 7 | 75174 | 177 | 29499169 |
Kounis syndrome | 12.40 | 9.93 | 19 | 75162 | 1810 | 29497536 |
Pharyngitis bacterial | 12.29 | 9.93 | 5 | 75176 | 59 | 29499287 |
Blood luteinising hormone decreased | 12.28 | 9.93 | 6 | 75175 | 112 | 29499234 |
Hypernatraemia | 12.25 | 9.93 | 44 | 75137 | 7342 | 29492004 |
Immunosuppressant drug level increased | 12.19 | 9.93 | 33 | 75148 | 4732 | 29494614 |
Blood creatinine increased | 12.18 | 9.93 | 148 | 75033 | 84954 | 29414392 |
Platelet count decreased | 12.13 | 9.93 | 190 | 74991 | 104482 | 29394864 |
Epileptic encephalopathy | 12.13 | 9.93 | 6 | 75175 | 115 | 29499231 |
Hydrocephalus | 12.12 | 9.93 | 31 | 75150 | 4296 | 29495050 |
Blood culture positive | 12.01 | 9.93 | 32 | 75149 | 4545 | 29494801 |
Pharyngitis streptococcal | 12.01 | 9.93 | 20 | 75161 | 2044 | 29497302 |
Hypothalamo-pituitary disorder | 12.00 | 9.93 | 12 | 75169 | 737 | 29498609 |
Sitting disability | 11.90 | 9.93 | 6 | 75175 | 120 | 29499226 |
Tracheobronchitis | 11.83 | 9.93 | 13 | 75168 | 891 | 29498455 |
Urticaria | 11.82 | 9.93 | 200 | 74981 | 54460 | 29444886 |
Body temperature decreased | 11.74 | 9.93 | 56 | 75125 | 10608 | 29488738 |
Adenoidal hypertrophy | 11.68 | 9.93 | 6 | 75175 | 125 | 29499221 |
Blood corticotrophin increased | 11.65 | 9.93 | 5 | 75176 | 68 | 29499278 |
Congenital adrenal gland hypoplasia | 11.65 | 9.93 | 3 | 75178 | 6 | 29499340 |
Renal disorder | 11.65 | 9.93 | 25 | 75156 | 22570 | 29476776 |
Proctitis | 11.62 | 9.93 | 20 | 75161 | 2099 | 29497247 |
Gastroenteritis | 11.61 | 9.93 | 63 | 75118 | 12553 | 29486793 |
Arm amputation | 11.55 | 9.93 | 6 | 75175 | 128 | 29499218 |
Wrong technique in product usage process | 11.55 | 9.93 | 41 | 75140 | 31387 | 29467959 |
Gonadotrophin deficiency | 11.43 | 9.93 | 4 | 75177 | 30 | 29499316 |
Hyperamylasaemia | 11.43 | 9.93 | 10 | 75171 | 518 | 29498828 |
Cerebral infarction | 11.36 | 9.93 | 29 | 75152 | 24646 | 29474700 |
Diplegia | 11.31 | 9.93 | 13 | 75168 | 936 | 29498410 |
Antibody test abnormal | 11.27 | 9.93 | 6 | 75175 | 135 | 29499211 |
Chronic kidney disease | 11.18 | 9.93 | 51 | 75130 | 36365 | 29462981 |
Serotonin syndrome | 11.16 | 9.93 | 17 | 75164 | 17495 | 29481851 |
Febrile convulsion | 11.15 | 9.93 | 10 | 75171 | 535 | 29498811 |
Myelitis transverse | 11.13 | 9.93 | 13 | 75168 | 952 | 29498394 |
Cortisol abnormal | 11.10 | 9.93 | 4 | 75177 | 33 | 29499313 |
Eye pruritus | 11.08 | 9.93 | 30 | 75151 | 4302 | 29495044 |
Bradycardia | 11.04 | 9.93 | 110 | 75071 | 65519 | 29433827 |
Leptotrichia infection | 11.04 | 9.93 | 5 | 75176 | 78 | 29499268 |
Suicidal ideation | 11.03 | 9.93 | 48 | 75133 | 34668 | 29464678 |
Tooth injury | 10.97 | 9.93 | 12 | 75169 | 818 | 29498528 |
Hepatic function abnormal | 10.89 | 9.93 | 57 | 75124 | 39202 | 29460144 |
Product dose omission issue | 10.82 | 9.93 | 176 | 75005 | 96207 | 29403139 |
Transplant failure | 10.78 | 9.93 | 23 | 75158 | 2833 | 29496513 |
Eczema | 10.74 | 9.93 | 66 | 75115 | 13760 | 29485586 |
Bone cyst | 10.72 | 9.93 | 10 | 75171 | 563 | 29498783 |
Intestinal stenosis | 10.59 | 9.93 | 18 | 75163 | 1870 | 29497476 |
Melaena | 10.59 | 9.93 | 42 | 75139 | 31134 | 29468212 |
Paraesthesia | 10.56 | 9.93 | 194 | 74987 | 53651 | 29445695 |
Unmasking of previously unidentified disease | 10.52 | 9.93 | 11 | 75170 | 712 | 29498634 |
Proteus infection | 10.45 | 9.93 | 12 | 75169 | 863 | 29498483 |
Tendonitis | 10.41 | 9.93 | 44 | 75137 | 7917 | 29491429 |
Pulmonary arterial hypertension | 10.41 | 9.93 | 3 | 75178 | 7446 | 29491900 |
Peptic ulcer haemorrhage | 10.40 | 9.93 | 9 | 75172 | 459 | 29498887 |
Gastric ulcer perforation | 10.40 | 9.93 | 12 | 75169 | 868 | 29498478 |
Vomiting projectile | 10.33 | 9.93 | 10 | 75171 | 590 | 29498756 |
Drug-induced liver injury | 10.32 | 9.93 | 25 | 75156 | 21630 | 29477716 |
Abdominal abscess | 10.31 | 9.93 | 27 | 75154 | 3797 | 29495549 |
Eosinophilia | 10.24 | 9.93 | 26 | 75155 | 22135 | 29477211 |
Multiple organ dysfunction syndrome | 10.24 | 9.93 | 221 | 74960 | 62895 | 29436451 |
Hepatic cirrhosis | 10.22 | 9.93 | 13 | 75168 | 14431 | 29484915 |
Botulism | 10.22 | 9.93 | 6 | 75175 | 164 | 29499182 |
Rhabdomyolysis | 10.19 | 9.93 | 102 | 75079 | 60706 | 29438640 |
Psychotic disorder | 10.10 | 9.93 | 23 | 75158 | 20331 | 29479015 |
Somnolence | 10.08 | 9.93 | 173 | 75008 | 93782 | 29405564 |
Depressed level of consciousness | 10.04 | 9.93 | 54 | 75127 | 36888 | 29462458 |
Superior sagittal sinus thrombosis | 10.01 | 9.93 | 7 | 75174 | 260 | 29499086 |
Inflammatory marker increased | 9.99 | 9.93 | 26 | 75155 | 3641 | 29495705 |
Delirium | 9.94 | 9.93 | 59 | 75122 | 39338 | 29460008 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Completed suicide | 544.59 | 9.42 | 20 | 181806 | 224394 | 64092512 |
Infusion related reaction | 453.09 | 9.42 | 1248 | 180578 | 163219 | 64153687 |
Toxicity to various agents | 385.63 | 9.42 | 278 | 181548 | 363235 | 63953671 |
Adrenocortical insufficiency acute | 361.48 | 9.42 | 166 | 181660 | 2399 | 64314507 |
Intentional product use issue | 344.21 | 9.42 | 802 | 181024 | 94562 | 64222344 |
Drug abuse | 313.56 | 9.42 | 14 | 181812 | 132360 | 64184546 |
Adrenal insufficiency | 292.99 | 9.42 | 339 | 181487 | 22148 | 64294758 |
Anti-cyclic citrullinated peptide antibody positive | 290.44 | 9.42 | 510 | 181316 | 49052 | 64267854 |
Pericarditis | 272.22 | 9.42 | 567 | 181259 | 61949 | 64254957 |
Wound | 269.19 | 9.42 | 637 | 181189 | 75840 | 64241066 |
Blood pressure fluctuation | 268.72 | 9.42 | 506 | 181320 | 51365 | 64265541 |
Glossodynia | 251.00 | 9.42 | 560 | 181266 | 64136 | 64252770 |
Pemphigus | 242.92 | 9.42 | 532 | 181294 | 60169 | 64256737 |
Systemic lupus erythematosus | 231.59 | 9.42 | 607 | 181219 | 77005 | 64239901 |
Hand deformity | 225.41 | 9.42 | 527 | 181299 | 62244 | 64254662 |
Discomfort | 223.66 | 9.42 | 615 | 181211 | 80263 | 64236643 |
Rheumatoid factor positive | 205.29 | 9.42 | 360 | 181466 | 34578 | 64282328 |
Death | 198.69 | 9.42 | 697 | 181129 | 482008 | 63834898 |
Craniopharyngioma | 197.37 | 9.42 | 64 | 181762 | 325 | 64316581 |
Duodenal ulcer perforation | 196.00 | 9.42 | 351 | 181475 | 34274 | 64282632 |
Colitis ulcerative | 189.94 | 9.42 | 277 | 181549 | 22751 | 64294155 |
Helicobacter infection | 189.76 | 9.42 | 367 | 181459 | 37995 | 64278911 |
Product use issue | 179.59 | 9.42 | 875 | 180951 | 150840 | 64166066 |
Off label use | 175.62 | 9.42 | 2627 | 179199 | 630179 | 63686727 |
Steroid withdrawal syndrome | 168.81 | 9.42 | 65 | 181761 | 585 | 64316321 |
Inappropriate schedule of product administration | 156.04 | 9.42 | 593 | 181233 | 91693 | 64225213 |
Synovitis | 154.78 | 9.42 | 621 | 181205 | 98469 | 64218437 |
Drug interaction | 154.12 | 9.42 | 515 | 181311 | 361568 | 63955338 |
Intentional overdose | 153.40 | 9.42 | 33 | 181793 | 89911 | 64226995 |
Arthropathy | 149.86 | 9.42 | 707 | 181119 | 120260 | 64196646 |
Overdose | 136.44 | 9.42 | 149 | 181677 | 159417 | 64157489 |
Hypersensitivity | 133.63 | 9.42 | 980 | 180846 | 195472 | 64121434 |
Alopecia | 130.03 | 9.42 | 856 | 180970 | 164834 | 64152072 |
Condition aggravated | 128.68 | 9.42 | 1609 | 180217 | 370817 | 63946089 |
Blister | 121.32 | 9.42 | 501 | 181325 | 80466 | 64236440 |
Secondary immunodeficiency | 119.89 | 9.42 | 82 | 181744 | 2642 | 64314264 |
Fall | 118.37 | 9.42 | 690 | 181136 | 416136 | 63900770 |
Drug hypersensitivity | 117.11 | 9.42 | 1103 | 180723 | 236712 | 64080194 |
Swelling | 112.80 | 9.42 | 806 | 181020 | 159412 | 64157494 |
Abdominal discomfort | 105.95 | 9.42 | 877 | 180949 | 181445 | 64135461 |
Irritable bowel syndrome | 105.08 | 9.42 | 286 | 181540 | 37083 | 64279823 |
Febrile bone marrow aplasia | 104.07 | 9.42 | 143 | 181683 | 11112 | 64305794 |
Pituitary tumour benign | 100.86 | 9.42 | 69 | 181757 | 2224 | 64314682 |
Maternal exposure during pregnancy | 99.39 | 9.42 | 533 | 181293 | 95351 | 64221555 |
Frequent bowel movements | 95.29 | 9.42 | 179 | 181647 | 18126 | 64298780 |
Heart rate irregular | 94.94 | 9.42 | 227 | 181599 | 27186 | 64289720 |
Hepatic enzyme increased | 92.19 | 9.42 | 655 | 181171 | 129288 | 64187618 |
Drug level below therapeutic | 87.37 | 9.42 | 106 | 181720 | 7278 | 64309628 |
Leukoencephalopathy | 87.35 | 9.42 | 103 | 181723 | 6864 | 64310042 |
Folliculitis | 86.37 | 9.42 | 232 | 181594 | 29845 | 64287061 |
Febrile neutropenia | 86.23 | 9.42 | 858 | 180968 | 186799 | 64130107 |
Hypopituitarism | 84.77 | 9.42 | 66 | 181760 | 2607 | 64314299 |
Acute kidney injury | 84.15 | 9.42 | 835 | 180991 | 448405 | 63868501 |
Interstitial lung disease | 83.80 | 9.42 | 91 | 181735 | 97641 | 64219265 |
Muscle injury | 83.16 | 9.42 | 211 | 181615 | 26226 | 64290680 |
Suicide attempt | 80.88 | 9.42 | 50 | 181776 | 70957 | 64245949 |
Rash | 78.92 | 9.42 | 1768 | 180058 | 456781 | 63860125 |
Sleep disorder due to general medical condition, insomnia type | 78.85 | 9.42 | 206 | 181620 | 26064 | 64290842 |
Faecal calprotectin increased | 76.61 | 9.42 | 71 | 181755 | 3569 | 64313337 |
Diabetes insipidus | 76.06 | 9.42 | 78 | 181748 | 4443 | 64312463 |
Body temperature fluctuation | 72.66 | 9.42 | 66 | 181760 | 3232 | 64313674 |
Hypofibrinogenaemia | 70.02 | 9.42 | 50 | 181776 | 1728 | 64315178 |
Anaemia | 69.97 | 9.42 | 706 | 181120 | 377974 | 63938932 |
Neoplasm recurrence | 69.32 | 9.42 | 68 | 181758 | 3671 | 64313235 |
Mycobacterium chelonae infection | 68.28 | 9.42 | 53 | 181773 | 2084 | 64314822 |
Myocardial infarction | 68.27 | 9.42 | 239 | 181587 | 165582 | 64151324 |
Secondary adrenocortical insufficiency | 66.03 | 9.42 | 54 | 181772 | 2291 | 64314615 |
Sedation | 65.24 | 9.42 | 18 | 181808 | 41444 | 64275462 |
Poor venous access | 64.10 | 9.42 | 121 | 181705 | 12296 | 64304610 |
Cortisol decreased | 63.39 | 9.42 | 46 | 181780 | 1631 | 64315275 |
Drug intolerance | 61.69 | 9.42 | 805 | 181021 | 187187 | 64129719 |
Hip arthroplasty | 61.61 | 9.42 | 165 | 181661 | 21186 | 64295720 |
Therapeutic response shortened | 61.29 | 9.42 | 106 | 181720 | 10064 | 64306842 |
Weight increased | 60.46 | 9.42 | 890 | 180936 | 212458 | 64104448 |
Bacterial infection | 60.45 | 9.42 | 181 | 181645 | 24769 | 64292137 |
Coma | 60.33 | 9.42 | 96 | 181730 | 87519 | 64229387 |
Aplastic anaemia | 60.25 | 9.42 | 126 | 181700 | 13794 | 64303112 |
Rheumatic fever | 60.16 | 9.42 | 100 | 181726 | 9194 | 64307712 |
Cardio-respiratory arrest | 57.74 | 9.42 | 119 | 181707 | 98274 | 64218632 |
Syncope | 56.65 | 9.42 | 240 | 181586 | 157395 | 64159511 |
Drug specific antibody present | 56.18 | 9.42 | 71 | 181755 | 5083 | 64311823 |
Adrenal suppression | 56.17 | 9.42 | 39 | 181787 | 1288 | 64315618 |
Pseudostroke | 55.94 | 9.42 | 16 | 181810 | 48 | 64316858 |
Intentional product misuse | 55.90 | 9.42 | 73 | 181753 | 72222 | 64244684 |
Cardiac failure | 55.01 | 9.42 | 190 | 181636 | 132183 | 64184723 |
Heart rate decreased | 54.27 | 9.42 | 302 | 181524 | 54765 | 64262141 |
Fistula | 54.01 | 9.42 | 98 | 181728 | 9663 | 64307243 |
Gastrointestinal haemorrhage | 53.58 | 9.42 | 192 | 181634 | 132120 | 64184786 |
Atrial fibrillation | 52.93 | 9.42 | 275 | 181551 | 170814 | 64146092 |
Perioral dermatitis | 52.54 | 9.42 | 22 | 181804 | 251 | 64316655 |
Renal impairment | 51.37 | 9.42 | 201 | 181625 | 134816 | 64182090 |
Cardiac failure congestive | 51.23 | 9.42 | 192 | 181634 | 130388 | 64186518 |
Human bocavirus infection | 50.75 | 9.42 | 27 | 181799 | 544 | 64316362 |
Hypophysitis | 48.62 | 9.42 | 55 | 181771 | 3504 | 64313402 |
Respiratory arrest | 48.05 | 9.42 | 47 | 181779 | 52938 | 64263968 |
Swollen joint count increased | 47.46 | 9.42 | 81 | 181745 | 7608 | 64309298 |
Meningitis candida | 47.13 | 9.42 | 17 | 181809 | 125 | 64316781 |
Septic shock | 46.90 | 9.42 | 479 | 181347 | 104958 | 64211948 |
Serotonin syndrome | 45.65 | 9.42 | 27 | 181799 | 39255 | 64277651 |
Parainfluenzae virus infection | 44.96 | 9.42 | 61 | 181765 | 4682 | 64312224 |
Lactic acidosis | 44.48 | 9.42 | 65 | 181761 | 61345 | 64255561 |
Insulin-like growth factor increased | 44.34 | 9.42 | 37 | 181789 | 1615 | 64315291 |
Product dose omission issue | 44.31 | 9.42 | 344 | 181482 | 194403 | 64122503 |
Pseudomonal sepsis | 43.79 | 9.42 | 63 | 181763 | 5109 | 64311797 |
Arthralgia | 43.26 | 9.42 | 1588 | 180238 | 440672 | 63876234 |
Urticaria thermal | 43.21 | 9.42 | 17 | 181809 | 163 | 64316743 |
Intentional self-injury | 43.16 | 9.42 | 14 | 181812 | 29030 | 64287876 |
Anal fissure | 43.07 | 9.42 | 61 | 181765 | 4875 | 64312031 |
Insulin-like growth factor decreased | 42.98 | 9.42 | 24 | 181802 | 534 | 64316372 |
Blood creatinine increased | 42.69 | 9.42 | 217 | 181609 | 135565 | 64181341 |
Device expulsion | 42.20 | 9.42 | 5 | 181821 | 21131 | 64295775 |
Clostridium difficile colitis | 41.97 | 9.42 | 170 | 181656 | 27053 | 64289853 |
Electrocardiogram QT prolonged | 41.00 | 9.42 | 103 | 181723 | 79345 | 64237561 |
Pruritus | 40.46 | 9.42 | 1160 | 180666 | 311240 | 64005666 |
Joint swelling | 40.30 | 9.42 | 841 | 180985 | 214541 | 64102365 |
Hypothalamo-pituitary disorder | 40.29 | 9.42 | 29 | 181797 | 1015 | 64315891 |
Bradycardia | 40.03 | 9.42 | 184 | 181642 | 118035 | 64198871 |
Colitis | 39.98 | 9.42 | 293 | 181533 | 58381 | 64258525 |
Neuroleptic malignant syndrome | 39.05 | 9.42 | 11 | 181815 | 24985 | 64291921 |
Contraindicated product administered | 38.87 | 9.42 | 470 | 181356 | 107359 | 64209547 |
Knee arthroplasty | 38.80 | 9.42 | 165 | 181661 | 26834 | 64290072 |
Drug level decreased | 38.48 | 9.42 | 94 | 181732 | 11409 | 64305497 |
Blood creatine phosphokinase increased | 37.69 | 9.42 | 67 | 181759 | 58491 | 64258415 |
Mucosal inflammation | 37.34 | 9.42 | 303 | 181523 | 62281 | 64254625 |
Pituitary tumour recurrent | 36.85 | 9.42 | 14 | 181812 | 121 | 64316785 |
Eczema herpeticum | 36.77 | 9.42 | 16 | 181810 | 202 | 64316704 |
Tendon pain | 36.65 | 9.42 | 56 | 181770 | 4792 | 64312114 |
Depressed level of consciousness | 36.51 | 9.42 | 113 | 181713 | 81323 | 64235583 |
Anal fistula | 36.00 | 9.42 | 58 | 181768 | 5195 | 64311711 |
Human herpesvirus 6 infection | 35.53 | 9.42 | 54 | 181772 | 4600 | 64312306 |
Pituitary haemorrhage | 34.86 | 9.42 | 17 | 181809 | 283 | 64316623 |
Live birth | 34.79 | 9.42 | 89 | 181737 | 11115 | 64305791 |
Lower respiratory tract infection | 34.36 | 9.42 | 413 | 181413 | 94201 | 64222705 |
Pneumoretroperitoneum | 33.90 | 9.42 | 12 | 181814 | 83 | 64316823 |
Hepatic function abnormal | 33.48 | 9.42 | 83 | 181743 | 64230 | 64252676 |
Shared psychotic disorder | 33.37 | 9.42 | 10 | 181816 | 37 | 64316869 |
Anal abscess | 32.54 | 9.42 | 68 | 181758 | 7440 | 64309466 |
Platelet count decreased | 32.44 | 9.42 | 309 | 181517 | 167402 | 64149504 |
Accidental exposure to product | 32.25 | 9.42 | 17 | 181809 | 26347 | 64290559 |
Injection site reaction | 32.24 | 9.42 | 51 | 181775 | 46613 | 64270293 |
Melaena | 32.06 | 9.42 | 64 | 181762 | 53484 | 64263422 |
Wrong technique in product usage process | 31.42 | 9.42 | 87 | 181739 | 64887 | 64252019 |
Malignant neoplasm progression | 31.31 | 9.42 | 188 | 181638 | 112683 | 64204223 |
Full blood count abnormal | 31.14 | 9.42 | 23 | 181803 | 29734 | 64287172 |
Impaired healing | 30.95 | 9.42 | 283 | 181543 | 60190 | 64256716 |
Epidural lipomatosis | 30.77 | 9.42 | 23 | 181803 | 854 | 64316052 |
Thymus hypoplasia | 30.71 | 9.42 | 19 | 181807 | 514 | 64316392 |
Maternal exposure timing unspecified | 30.64 | 9.42 | 38 | 181788 | 2669 | 64314237 |
Cerebrovascular accident | 30.37 | 9.42 | 245 | 181581 | 137338 | 64179568 |
Cognitive disorder | 30.34 | 9.42 | 69 | 181757 | 55018 | 64261888 |
Injury | 30.18 | 9.42 | 265 | 181561 | 55727 | 64261179 |
Suicidal ideation | 30.07 | 9.42 | 92 | 181734 | 66450 | 64250456 |
Pneumonia | 30.04 | 9.42 | 1281 | 180545 | 558295 | 63758611 |
Candida infection | 28.78 | 9.42 | 169 | 181657 | 31250 | 64285656 |
Injection site erythema | 28.48 | 9.42 | 103 | 181723 | 70697 | 64246209 |
Norovirus test positive | 28.36 | 9.42 | 17 | 181809 | 434 | 64316472 |
Hyperadrenocorticism | 28.25 | 9.42 | 15 | 181811 | 301 | 64316605 |
Urticaria | 28.12 | 9.42 | 577 | 181249 | 146740 | 64170166 |
Extrapyramidal disorder | 28.06 | 9.42 | 10 | 181816 | 19542 | 64297364 |
Leukopenia | 27.89 | 9.42 | 169 | 181657 | 101073 | 64215833 |
Stomatitis | 27.85 | 9.42 | 449 | 181377 | 109156 | 64207750 |
Disease progression | 27.84 | 9.42 | 260 | 181566 | 141420 | 64175486 |
Haemoglobin decreased | 27.72 | 9.42 | 385 | 181441 | 194678 | 64122228 |
Flushing | 27.55 | 9.42 | 341 | 181485 | 78307 | 64238599 |
Gastrointestinal disorder | 27.27 | 9.42 | 379 | 181447 | 89330 | 64227576 |
Transient ischaemic attack | 27.15 | 9.42 | 52 | 181774 | 44130 | 64272776 |
Lymphoid tissue hypoplasia | 27.02 | 9.42 | 17 | 181809 | 474 | 64316432 |
Injection site swelling | 26.90 | 9.42 | 47 | 181779 | 41306 | 64275600 |
Accidental overdose | 26.86 | 9.42 | 33 | 181793 | 33524 | 64283382 |
Hypothalamic pituitary adrenal axis suppression | 26.41 | 9.42 | 14 | 181812 | 280 | 64316626 |
Myelopathy | 26.04 | 9.42 | 43 | 181783 | 3931 | 64312975 |
Epiphysiolysis | 25.87 | 9.42 | 10 | 181816 | 91 | 64316815 |
Diarrhoea haemorrhagic | 25.84 | 9.42 | 80 | 181746 | 11147 | 64305759 |
Thermophobia | 25.83 | 9.42 | 9 | 181817 | 59 | 64316847 |
Pneumatosis intestinalis | 25.81 | 9.42 | 50 | 181776 | 5179 | 64311727 |
Chronic obstructive pulmonary disease | 25.61 | 9.42 | 108 | 181718 | 70940 | 64245966 |
Exposure during pregnancy | 25.60 | 9.42 | 333 | 181493 | 77342 | 64239564 |
Natural killer-cell leukaemia | 25.59 | 9.42 | 10 | 181816 | 94 | 64316812 |
Eczema | 25.40 | 9.42 | 157 | 181669 | 29563 | 64287343 |
Blood pressure increased | 24.92 | 9.42 | 650 | 181176 | 171902 | 64145004 |
Astrocytoma | 24.76 | 9.42 | 12 | 181814 | 197 | 64316709 |
Perfume sensitivity | 24.74 | 9.42 | 18 | 181808 | 641 | 64316265 |
Hyperkalaemia | 24.72 | 9.42 | 175 | 181651 | 100954 | 64215952 |
Nausea | 24.32 | 9.42 | 1897 | 179929 | 783903 | 63533003 |
Somnolence | 24.16 | 9.42 | 416 | 181410 | 203229 | 64113677 |
Tendon rupture | 24.12 | 9.42 | 76 | 181750 | 10691 | 64306215 |
Ill-defined disorder | 24.00 | 9.42 | 209 | 181617 | 43843 | 64273063 |
Musculoskeletal injury | 23.82 | 9.42 | 11 | 181815 | 161 | 64316745 |
Hypernatraemia | 23.69 | 9.42 | 82 | 181744 | 12107 | 64304799 |
Dry skin | 23.49 | 9.42 | 234 | 181592 | 50927 | 64265979 |
Respiratory depression | 23.41 | 9.42 | 19 | 181807 | 23424 | 64293482 |
Type 2 diabetes mellitus | 23.24 | 9.42 | 170 | 181656 | 33850 | 64283056 |
Viral infection | 23.22 | 9.42 | 178 | 181648 | 35962 | 64280944 |
Parkinsonism | 23.06 | 9.42 | 6 | 181820 | 14367 | 64302539 |
Growth retardation | 22.83 | 9.42 | 25 | 181801 | 1536 | 64315370 |
Cerebrospinal fluid leakage | 22.73 | 9.42 | 23 | 181803 | 1289 | 64315617 |
Cardiac disorder | 22.58 | 9.42 | 81 | 181745 | 55735 | 64261171 |
Tendon disorder | 22.53 | 9.42 | 53 | 181773 | 6279 | 64310627 |
Abscess bacterial | 22.43 | 9.42 | 18 | 181808 | 743 | 64316163 |
Pulmonary arterial hypertension | 22.43 | 9.42 | 23 | 181803 | 25344 | 64291562 |
Rhinovirus infection | 22.42 | 9.42 | 52 | 181774 | 6104 | 64310802 |
Normal tension glaucoma | 22.28 | 9.42 | 8 | 181818 | 58 | 64316848 |
Subdural haematoma | 22.02 | 9.42 | 28 | 181798 | 28026 | 64288880 |
Female genital tract fistula | 21.95 | 9.42 | 32 | 181794 | 2626 | 64314280 |
Nasopharyngitis | 21.85 | 9.42 | 715 | 181111 | 195358 | 64121548 |
Cystitis bacterial | 21.68 | 9.42 | 14 | 181812 | 409 | 64316497 |
Enterobacter infection | 21.59 | 9.42 | 38 | 181788 | 3658 | 64313248 |
Schizophrenia | 21.43 | 9.42 | 3 | 181823 | 11165 | 64305741 |
Hypogonadism | 21.42 | 9.42 | 20 | 181806 | 1015 | 64315891 |
Allergy test positive | 21.29 | 9.42 | 14 | 181812 | 422 | 64316484 |
Hepatotoxicity | 21.25 | 9.42 | 51 | 181775 | 39911 | 64276995 |
White blood cell count decreased | 21.20 | 9.42 | 315 | 181511 | 157522 | 64159384 |
Abdominal pain | 20.95 | 9.42 | 1079 | 180747 | 311296 | 64005610 |
Therapeutic product effect decreased | 20.77 | 9.42 | 448 | 181378 | 114903 | 64202003 |
Symptom masked | 20.67 | 9.42 | 21 | 181805 | 1183 | 64315723 |
Drug level above therapeutic | 20.59 | 9.42 | 54 | 181772 | 6847 | 64310059 |
Adrenocorticotropic hormone deficiency | 20.51 | 9.42 | 18 | 181808 | 842 | 64316064 |
Blood corticotrophin decreased | 20.49 | 9.42 | 13 | 181813 | 368 | 64316538 |
Rhabdomyolysis | 20.39 | 9.42 | 163 | 181663 | 91563 | 64225343 |
Renal failure | 20.33 | 9.42 | 375 | 181451 | 181313 | 64135593 |
Hyperemesis gravidarum | 20.24 | 9.42 | 13 | 181813 | 376 | 64316530 |
Cardiac arrest | 20.17 | 9.42 | 309 | 181517 | 153755 | 64163151 |
Hospitalisation | 19.95 | 9.42 | 127 | 181699 | 75080 | 64241826 |
Oxygen saturation abnormal | 19.94 | 9.42 | 36 | 181790 | 3535 | 64313371 |
Balance disorder | 19.66 | 9.42 | 147 | 181679 | 83779 | 64233127 |
Chronic sinusitis | 19.56 | 9.42 | 50 | 181776 | 6242 | 64310664 |
Gastroenteritis norovirus | 19.51 | 9.42 | 31 | 181795 | 2744 | 64314162 |
Proctalgia | 19.42 | 9.42 | 56 | 181770 | 7503 | 64309403 |
Oedema peripheral | 19.41 | 9.42 | 448 | 181378 | 209869 | 64107037 |
Airway peak pressure increased | 19.38 | 9.42 | 12 | 181814 | 325 | 64316581 |
Coronary artery disease | 19.32 | 9.42 | 96 | 181730 | 60337 | 64256569 |
Loss of consciousness | 19.27 | 9.42 | 298 | 181528 | 148067 | 64168839 |
Hallucination | 19.27 | 9.42 | 123 | 181703 | 72665 | 64244241 |
Pouchitis | 19.16 | 9.42 | 17 | 181809 | 807 | 64316099 |
Poisoning deliberate | 19.11 | 9.42 | 7 | 181819 | 13451 | 64303455 |
Breast cancer | 19.07 | 9.42 | 33 | 181793 | 29115 | 64287791 |
Blood corticotrophin increased | 19.00 | 9.42 | 9 | 181817 | 140 | 64316766 |
Hepatic cirrhosis | 18.88 | 9.42 | 28 | 181798 | 26270 | 64290636 |
Product prescribing error | 18.76 | 9.42 | 45 | 181781 | 35224 | 64281682 |
Osteonecrosis of jaw | 18.76 | 9.42 | 54 | 181772 | 39771 | 64277135 |
Fibromyalgia | 18.68 | 9.42 | 168 | 181658 | 35563 | 64281343 |
Cerebral vasoconstriction | 18.62 | 9.42 | 20 | 181806 | 1202 | 64315704 |
Mastocytosis | 18.57 | 9.42 | 13 | 181813 | 435 | 64316471 |
Body temperature decreased | 18.54 | 9.42 | 131 | 181695 | 25797 | 64291109 |
Injection site pain | 18.38 | 9.42 | 213 | 181613 | 111195 | 64205711 |
Product quality issue | 18.37 | 9.42 | 35 | 181791 | 29764 | 64287142 |
Bronchopulmonary aspergillosis | 18.35 | 9.42 | 104 | 181722 | 18981 | 64297925 |
Fluid retention | 18.31 | 9.42 | 96 | 181730 | 59510 | 64257396 |
Coronavirus infection | 18.30 | 9.42 | 45 | 181781 | 5485 | 64311421 |
Haematuria | 18.23 | 9.42 | 98 | 181728 | 60373 | 64256533 |
Cerebral haemorrhage | 18.20 | 9.42 | 78 | 181748 | 51012 | 64265894 |
Morganella infection | 18.10 | 9.42 | 18 | 181808 | 988 | 64315918 |
Pituitary infarction | 18.08 | 9.42 | 7 | 181819 | 64 | 64316842 |
Unevaluable event | 18.04 | 9.42 | 77 | 181749 | 50412 | 64266494 |
Rash erythematous | 17.96 | 9.42 | 213 | 181613 | 48420 | 64268486 |
Chronic kidney disease | 17.95 | 9.42 | 93 | 181733 | 57826 | 64259080 |
Glioblastoma multiforme | 17.92 | 9.42 | 19 | 181807 | 1125 | 64315781 |
Thrombocytopenia | 17.88 | 9.42 | 487 | 181339 | 223314 | 64093592 |
Acute myocardial infarction | 17.85 | 9.42 | 119 | 181707 | 69599 | 64247307 |
Soft tissue mass | 17.73 | 9.42 | 17 | 181809 | 892 | 64316014 |
Therapy cessation | 17.64 | 9.42 | 41 | 181785 | 32448 | 64284458 |
Cerebral microangiopathy | 17.61 | 9.42 | 10 | 181816 | 230 | 64316676 |
Aggression | 17.46 | 9.42 | 69 | 181757 | 46163 | 64270743 |
Asthenia | 17.45 | 9.42 | 1008 | 180818 | 427036 | 63889870 |
Drug-induced liver injury | 17.43 | 9.42 | 72 | 181754 | 47571 | 64269335 |
Agitation | 17.42 | 9.42 | 162 | 181664 | 88205 | 64228701 |
Salpingo-oophorectomy unilateral | 17.39 | 9.42 | 13 | 181813 | 483 | 64316423 |
Incorrect dose administered | 17.37 | 9.42 | 254 | 181572 | 60511 | 64256395 |
Labelled drug-drug interaction medication error | 17.34 | 9.42 | 22 | 181804 | 22040 | 64294866 |
Metabolic acidosis | 17.24 | 9.42 | 123 | 181703 | 70835 | 64246071 |
Angina pectoris | 17.21 | 9.42 | 67 | 181759 | 45014 | 64271892 |
Adrenal disorder | 17.16 | 9.42 | 22 | 181804 | 1598 | 64315308 |
Mydriasis | 17.13 | 9.42 | 11 | 181815 | 15301 | 64301605 |
Therapeutic reaction time decreased | 17.04 | 9.42 | 24 | 181802 | 1908 | 64314998 |
Orthostatic hypotension | 16.87 | 9.42 | 71 | 181755 | 46667 | 64270239 |
Unmasking of previously unidentified disease | 16.87 | 9.42 | 22 | 181804 | 1625 | 64315281 |
Skin weeping | 16.80 | 9.42 | 14 | 181812 | 610 | 64316296 |
Deep vein thrombosis postoperative | 16.74 | 9.42 | 20 | 181806 | 1351 | 64315555 |
Natural killer cell count decreased | 16.65 | 9.42 | 6 | 181820 | 44 | 64316862 |
Peptic ulcer haemorrhage | 16.60 | 9.42 | 16 | 181810 | 845 | 64316061 |
Drug withdrawal syndrome | 16.58 | 9.42 | 40 | 181786 | 31251 | 64285655 |
Splenic peliosis | 16.58 | 9.42 | 5 | 181821 | 19 | 64316887 |
Red blood cell sedimentation rate abnormal | 16.55 | 9.42 | 13 | 181813 | 16293 | 64300613 |
Neutropenia | 16.51 | 9.42 | 532 | 181294 | 239092 | 64077814 |
Vertigo | 16.51 | 9.42 | 98 | 181728 | 58913 | 64257993 |
Liver function test abnormal | 16.43 | 9.42 | 99 | 181727 | 59302 | 64257604 |
Glioma | 16.40 | 9.42 | 13 | 181813 | 527 | 64316379 |
Delusion | 16.31 | 9.42 | 16 | 181810 | 17998 | 64298908 |
Viraemia | 16.18 | 9.42 | 26 | 181800 | 2323 | 64314583 |
Hypercalcaemia | 15.99 | 9.42 | 41 | 181785 | 31375 | 64285531 |
Eosinophilic oesophagitis | 15.91 | 9.42 | 12 | 181814 | 452 | 64316454 |
Anaplastic astrocytoma | 15.89 | 9.42 | 8 | 181818 | 143 | 64316763 |
Dermatitis diaper | 15.86 | 9.42 | 10 | 181816 | 280 | 64316626 |
Strongyloidiasis | 15.81 | 9.42 | 30 | 181796 | 3060 | 64313846 |
Oesophageal perforation | 15.80 | 9.42 | 17 | 181809 | 1024 | 64315882 |
Hypertriglyceridaemia | 15.73 | 9.42 | 68 | 181758 | 11137 | 64305769 |
Neutropenic sepsis | 15.73 | 9.42 | 116 | 181710 | 23156 | 64293750 |
Diplegia | 15.70 | 9.42 | 21 | 181805 | 1590 | 64315316 |
Pyoderma gangrenosum | 15.62 | 9.42 | 30 | 181796 | 3088 | 64313818 |
Herpes simplex | 15.61 | 9.42 | 65 | 181761 | 10471 | 64306435 |
Drug resistance | 15.52 | 9.42 | 49 | 181777 | 35053 | 64281853 |
Metastases to bone | 15.42 | 9.42 | 21 | 181805 | 20414 | 64296492 |
Toxic skin eruption | 15.39 | 9.42 | 19 | 181807 | 19265 | 64297641 |
Diffuse large B-cell lymphoma | 15.39 | 9.42 | 5 | 181821 | 10356 | 64306550 |
Enteritis | 15.23 | 9.42 | 71 | 181755 | 12006 | 64304900 |
Tubulointerstitial nephritis | 15.23 | 9.42 | 41 | 181785 | 30868 | 64286038 |
Therapeutic product effect incomplete | 15.14 | 9.42 | 203 | 181623 | 103279 | 64213627 |
Haematochezia | 15.06 | 9.42 | 267 | 181559 | 66106 | 64250800 |
Tuberculosis gastrointestinal | 15.03 | 9.42 | 12 | 181814 | 492 | 64316414 |
Lichen planus | 15 | 9.42 | 25 | 181801 | 2303 | 64314603 |
Pituitary tumour | 14.95 | 9.42 | 17 | 181809 | 1089 | 64315817 |
Angina unstable | 14.87 | 9.42 | 13 | 181813 | 15454 | 64301452 |
Myelodysplastic syndrome | 14.82 | 9.42 | 35 | 181791 | 27544 | 64289362 |
International normalised ratio increased | 14.82 | 9.42 | 147 | 181679 | 79020 | 64237886 |
Blood growth hormone increased | 14.80 | 9.42 | 13 | 181813 | 609 | 64316297 |
Excessive eye blinking | 14.76 | 9.42 | 18 | 181808 | 1242 | 64315664 |
Dyskinesia | 14.74 | 9.42 | 59 | 181767 | 39329 | 64277577 |
Mucous stools | 14.60 | 9.42 | 30 | 181796 | 3243 | 64313663 |
Blood cholesterol increased | 14.60 | 9.42 | 210 | 181616 | 49856 | 64267050 |
Multimorbidity | 14.44 | 9.42 | 16 | 181810 | 996 | 64315910 |
Cerebral infarction | 14.42 | 9.42 | 63 | 181763 | 40981 | 64275925 |
Blood pressure diastolic decreased | 14.41 | 9.42 | 110 | 181716 | 22191 | 64294715 |
Cortisol abnormal | 14.29 | 9.42 | 6 | 181820 | 69 | 64316837 |
Tendonitis | 14.22 | 9.42 | 102 | 181724 | 20180 | 64296726 |
Pulmonary hypertension | 14.09 | 9.42 | 68 | 181758 | 43071 | 64273835 |
Adjustment disorder with depressed mood | 14.02 | 9.42 | 25 | 181801 | 2432 | 64314474 |
Medication error | 13.97 | 9.42 | 83 | 181743 | 49883 | 64267023 |
Blood potassium increased | 13.94 | 9.42 | 33 | 181793 | 25947 | 64290959 |
Multiple sclerosis relapse | 13.93 | 9.42 | 64 | 181762 | 41071 | 64275835 |
Excessive skin | 13.91 | 9.42 | 7 | 181819 | 125 | 64316781 |
Skin fragility | 13.85 | 9.42 | 14 | 181812 | 784 | 64316122 |
Cholangitis infective | 13.84 | 9.42 | 11 | 181815 | 448 | 64316458 |
Kounis syndrome | 13.82 | 9.42 | 28 | 181798 | 2997 | 64313909 |
Intestinal stenosis | 13.80 | 9.42 | 29 | 181797 | 3185 | 64313721 |
Defaecation urgency | 13.77 | 9.42 | 33 | 181793 | 3956 | 64312950 |
Enthesopathy | 13.71 | 9.42 | 5 | 181821 | 9633 | 64307273 |
Clostridium difficile infection | 13.62 | 9.42 | 159 | 181667 | 36004 | 64280902 |
Pulmonary oedema | 13.53 | 9.42 | 149 | 181677 | 78525 | 64238381 |
Cushing's syndrome | 13.51 | 9.42 | 15 | 181811 | 936 | 64315970 |
Anti-cyclic citrullinated peptide antibody | 13.44 | 9.42 | 18 | 181808 | 1364 | 64315542 |
Optic glioma | 13.39 | 9.42 | 5 | 181821 | 41 | 64316865 |
Chorioretinopathy | 13.37 | 9.42 | 23 | 181803 | 2174 | 64314732 |
Cryptococcal meningoencephalitis | 13.35 | 9.42 | 8 | 181818 | 204 | 64316702 |
Jaundice | 13.34 | 9.42 | 81 | 181745 | 48431 | 64268475 |
Wheezing | 13.26 | 9.42 | 309 | 181517 | 80270 | 64236636 |
Faecal calprotectin abnormal | 13.25 | 9.42 | 7 | 181819 | 139 | 64316767 |
Adenoidal hypertrophy | 13.25 | 9.42 | 7 | 181819 | 139 | 64316767 |
Rectal abscess | 13.23 | 9.42 | 19 | 181807 | 1538 | 64315368 |
Thyroxine free decreased | 13.21 | 9.42 | 14 | 181812 | 829 | 64316077 |
B-lymphocyte count increased | 13.20 | 9.42 | 7 | 181819 | 140 | 64316766 |
Lip dry | 13.19 | 9.42 | 37 | 181789 | 4881 | 64312025 |
Pyrexia | 13.18 | 9.42 | 1782 | 180044 | 556862 | 63760044 |
Cardiac failure acute | 13.15 | 9.42 | 16 | 181810 | 16328 | 64300578 |
Muscle rigidity | 13.14 | 9.42 | 18 | 181808 | 17455 | 64299451 |
Epistaxis | 13.12 | 9.42 | 196 | 181630 | 97935 | 64218971 |
Clostridium test positive | 13.10 | 9.42 | 33 | 181793 | 4082 | 64312824 |
Stevens-Johnson syndrome | 13.09 | 9.42 | 151 | 181675 | 34098 | 64282808 |
Antithrombin III | 13.05 | 9.42 | 6 | 181820 | 87 | 64316819 |
Product storage error | 13.04 | 9.42 | 11 | 181815 | 13307 | 64303599 |
Rheumatoid arthritis | 12.99 | 9.42 | 358 | 181468 | 163936 | 64152970 |
Aborted pregnancy | 12.99 | 9.42 | 5 | 181821 | 45 | 64316861 |
Facet joint syndrome | 12.98 | 9.42 | 21 | 181805 | 1888 | 64315018 |
Uterine cyst | 12.94 | 9.42 | 9 | 181817 | 298 | 64316608 |
Underdose | 12.93 | 9.42 | 34 | 181792 | 25795 | 64291111 |
Palmar-plantar erythrodysaesthesia syndrome | 12.91 | 9.42 | 40 | 181786 | 28779 | 64288127 |
Creatinine renal clearance decreased | 12.83 | 9.42 | 13 | 181813 | 14408 | 64302498 |
Sitting disability | 12.81 | 9.42 | 7 | 181819 | 149 | 64316757 |
Germ cell cancer | 12.77 | 9.42 | 7 | 181819 | 150 | 64316756 |
Abdominal abscess | 12.77 | 9.42 | 43 | 181783 | 6261 | 64310645 |
Posturing | 12.75 | 9.42 | 15 | 181811 | 997 | 64315909 |
Arrhythmia | 12.75 | 9.42 | 92 | 181734 | 52852 | 64264054 |
Chills | 12.67 | 9.42 | 490 | 181336 | 136774 | 64180132 |
Erythema nodosum | 12.63 | 9.42 | 32 | 181794 | 3972 | 64312934 |
Asphyxia | 12.63 | 9.42 | 57 | 181769 | 9509 | 64307397 |
Myelitis transverse | 12.63 | 9.42 | 19 | 181807 | 1604 | 64315302 |
Shunt malfunction | 12.62 | 9.42 | 8 | 181818 | 226 | 64316680 |
Renal disorder | 12.59 | 9.42 | 54 | 181772 | 35311 | 64281595 |
Skin exfoliation | 12.59 | 9.42 | 187 | 181639 | 44698 | 64272208 |
Catatonia | 12.58 | 9.42 | 3 | 181823 | 7617 | 64309289 |
Hyperamylasaemia | 12.57 | 9.42 | 14 | 181812 | 877 | 64316029 |
Dysarthria | 12.55 | 9.42 | 107 | 181719 | 59299 | 64257607 |
Dizziness | 12.54 | 9.42 | 1043 | 180783 | 429120 | 63887786 |
Lung neoplasm malignant | 12.52 | 9.42 | 26 | 181800 | 21422 | 64295484 |
Cryptococcal fungaemia | 12.37 | 9.42 | 7 | 181819 | 160 | 64316746 |
PO2 decreased | 12.26 | 9.42 | 25 | 181801 | 2688 | 64314218 |
PCO2 increased | 12.24 | 9.42 | 19 | 181807 | 1648 | 64315258 |
Myelosuppression | 12.21 | 9.42 | 31 | 181795 | 23799 | 64293107 |
Neutrophil count decreased | 12.19 | 9.42 | 149 | 181677 | 77047 | 64239859 |
Anorectal ulcer | 12.18 | 9.42 | 5 | 181821 | 54 | 64316852 |
Non-consummation | 12.18 | 9.42 | 5 | 181821 | 54 | 64316852 |
Bladder cancer | 12.12 | 9.42 | 8 | 181818 | 10966 | 64305940 |
Mucosal hyperaemia | 12.10 | 9.42 | 5 | 181821 | 55 | 64316851 |
Erythema | 12.08 | 9.42 | 644 | 181182 | 186426 | 64130480 |
Inflammatory bowel disease | 12.03 | 9.42 | 34 | 181792 | 4504 | 64312402 |
Oropharyngeal pain | 12.03 | 9.42 | 332 | 181494 | 88535 | 64228371 |
Aspartate aminotransferase increased | 11.95 | 9.42 | 252 | 181574 | 119536 | 64197370 |
Conus medullaris syndrome | 11.92 | 9.42 | 4 | 181822 | 23 | 64316883 |
Klebsiella infection | 11.88 | 9.42 | 71 | 181755 | 13210 | 64303696 |
Aspergillus infection | 11.85 | 9.42 | 83 | 181743 | 16296 | 64300610 |
Upper gastrointestinal haemorrhage | 11.81 | 9.42 | 55 | 181771 | 35165 | 64281741 |
Contusion | 11.77 | 9.42 | 412 | 181414 | 113553 | 64203353 |
Dyspnoea exertional | 11.76 | 9.42 | 142 | 181684 | 73588 | 64243318 |
Atrial flutter | 11.74 | 9.42 | 23 | 181803 | 19357 | 64297549 |
Rheumatoid nodule | 11.73 | 9.42 | 11 | 181815 | 12640 | 64304266 |
Serum sickness | 11.68 | 9.42 | 27 | 181799 | 3162 | 64313744 |
Anal inflammation | 11.67 | 9.42 | 10 | 181816 | 453 | 64316453 |
Loss of employment | 11.65 | 9.42 | 20 | 181806 | 1887 | 64315019 |
Infection | 11.65 | 9.42 | 635 | 181191 | 184245 | 64132661 |
Status asthmaticus | 11.62 | 9.42 | 14 | 181812 | 954 | 64315952 |
Lichenification | 11.61 | 9.42 | 12 | 181814 | 690 | 64316216 |
Pharyngeal paraesthesia | 11.58 | 9.42 | 20 | 181806 | 1897 | 64315009 |
Thyrotoxic crisis | 11.58 | 9.42 | 15 | 181811 | 1101 | 64315805 |
Posterior reversible encephalopathy syndrome | 11.54 | 9.42 | 107 | 181719 | 22839 | 64294067 |
Abdominal compartment syndrome | 11.52 | 9.42 | 17 | 181809 | 1411 | 64315495 |
Treatment failure | 11.50 | 9.42 | 420 | 181406 | 116396 | 64200510 |
Neurotoxicity | 11.47 | 9.42 | 123 | 181703 | 27281 | 64289625 |
Gastrointestinal inflammation | 11.46 | 9.42 | 41 | 181785 | 6154 | 64310752 |
Nasal polyps | 11.45 | 9.42 | 29 | 181797 | 3600 | 64313306 |
Enterobacter bacteraemia | 11.44 | 9.42 | 11 | 181815 | 579 | 64316327 |
Pseudomonas infection | 11.44 | 9.42 | 88 | 181738 | 17795 | 64299111 |
Proteinuria | 11.37 | 9.42 | 40 | 181786 | 27683 | 64289223 |
Cushingoid | 11.34 | 9.42 | 47 | 181779 | 7556 | 64309350 |
Cytomegalovirus chorioretinitis | 11.30 | 9.42 | 35 | 181791 | 4877 | 64312029 |
Pain | 11.30 | 9.42 | 1751 | 180075 | 551760 | 63765146 |
Skin wrinkling | 11.27 | 9.42 | 14 | 181812 | 985 | 64315921 |
Intestinal resection | 11.27 | 9.42 | 26 | 181800 | 3042 | 64313864 |
Basilar artery aneurysm | 11.26 | 9.42 | 4 | 181822 | 28 | 64316878 |
Blood culture positive | 11.24 | 9.42 | 48 | 181778 | 7820 | 64309086 |
Delirium | 11.14 | 9.42 | 133 | 181693 | 69061 | 64247845 |
Breast cancer stage III | 11.09 | 9.42 | 25 | 181801 | 2880 | 64314026 |
Hypoperfusion | 11.06 | 9.42 | 22 | 181804 | 2324 | 64314582 |
Hypercapnia | 11.04 | 9.42 | 47 | 181779 | 7647 | 64309259 |
Femur fracture | 11.04 | 9.42 | 54 | 181772 | 34081 | 64282825 |
Psychotic disorder | 11.01 | 9.42 | 55 | 181771 | 34523 | 64282383 |
Visual pathway disorder | 10.97 | 9.42 | 5 | 181821 | 71 | 64316835 |
Tinea infection | 10.91 | 9.42 | 14 | 181812 | 1018 | 64315888 |
Acute graft versus host disease | 10.90 | 9.42 | 6 | 181820 | 9078 | 64307828 |
Blood thyroid stimulating hormone decreased | 10.88 | 9.42 | 36 | 181790 | 5194 | 64311712 |
Adverse event | 10.87 | 9.42 | 164 | 181662 | 39325 | 64277581 |
Purpura | 10.86 | 9.42 | 20 | 181806 | 17226 | 64299680 |
Sedation complication | 10.84 | 9.42 | 8 | 181818 | 10346 | 64306560 |
Gonadotrophin deficiency | 10.80 | 9.42 | 4 | 181822 | 32 | 64316874 |
Fatigue | 10.75 | 9.42 | 2326 | 179500 | 746404 | 63570502 |
Treatment noncompliance | 10.74 | 9.42 | 75 | 181751 | 43407 | 64273499 |
Akathisia | 10.68 | 9.42 | 10 | 181816 | 11500 | 64305406 |
Coronary artery dissection | 10.66 | 9.42 | 13 | 181813 | 897 | 64316009 |
Phaeochromocytoma crisis | 10.66 | 9.42 | 8 | 181818 | 299 | 64316607 |
Vaginal discharge | 10.65 | 9.42 | 30 | 181796 | 3967 | 64312939 |
Gram stain positive | 10.64 | 9.42 | 6 | 181820 | 136 | 64316770 |
Loss of personal independence in daily activities | 10.64 | 9.42 | 142 | 181684 | 72312 | 64244594 |
Lymphocytic hypophysitis | 10.63 | 9.42 | 9 | 181817 | 401 | 64316505 |
Toxic leukoencephalopathy | 10.61 | 9.42 | 13 | 181813 | 902 | 64316004 |
Ruptured cerebral aneurysm | 10.55 | 9.42 | 10 | 181816 | 517 | 64316389 |
Encephalitis autoimmune | 10.53 | 9.42 | 19 | 181807 | 1865 | 64315041 |
Bronchial haemorrhage | 10.51 | 9.42 | 15 | 181811 | 1207 | 64315699 |
Atrioventricular block | 10.50 | 9.42 | 11 | 181815 | 12004 | 64304902 |
Hypomagnesaemia | 10.49 | 9.42 | 62 | 181764 | 37314 | 64279592 |
Manipulation | 10.49 | 9.42 | 5 | 181821 | 79 | 64316827 |
Encephalitis | 10.48 | 9.42 | 66 | 181760 | 12505 | 64304401 |
Periorbital infection | 10.43 | 9.42 | 5 | 181821 | 80 | 64316826 |
Agranulocytosis | 10.42 | 9.42 | 64 | 181762 | 38165 | 64278741 |
Reaction to preservatives | 10.41 | 9.42 | 6 | 181820 | 142 | 64316764 |
Oesophageal adenocarcinoma recurrent | 10.39 | 9.42 | 4 | 181822 | 36 | 64316870 |
Increased bronchial secretion | 10.34 | 9.42 | 24 | 181802 | 2818 | 64314088 |
Disseminated aspergillosis | 10.30 | 9.42 | 11 | 181815 | 657 | 64316249 |
Pneumonia aspiration | 10.29 | 9.42 | 112 | 181714 | 59159 | 64257747 |
Thyroglossal cyst infection | 10.29 | 9.42 | 4 | 181822 | 37 | 64316869 |
Adenoidectomy | 10.27 | 9.42 | 5 | 181821 | 83 | 64316823 |
Eosinophilia | 10.25 | 9.42 | 64 | 181762 | 38012 | 64278894 |
Autoimmune nephritis | 10.24 | 9.42 | 10 | 181816 | 537 | 64316369 |
Nightmare | 10.23 | 9.42 | 28 | 181798 | 20965 | 64295941 |
Right ventricular failure | 10.19 | 9.42 | 29 | 181797 | 21442 | 64295464 |
Anorectal disorder | 10.14 | 9.42 | 19 | 181807 | 1920 | 64314986 |
Enterococcal sepsis | 10.13 | 9.42 | 22 | 181804 | 2472 | 64314434 |
Wrong technique in device usage process | 10.12 | 9.42 | 24 | 181802 | 2858 | 64314048 |
Glucocorticoid deficiency | 10.10 | 9.42 | 10 | 181816 | 546 | 64316360 |
Meningitis tuberculous | 10.10 | 9.42 | 14 | 181812 | 1097 | 64315809 |
Oesophageal candidiasis | 10.01 | 9.42 | 47 | 181779 | 7970 | 64308936 |
Respiratory rate increased | 10.00 | 9.42 | 87 | 181739 | 18244 | 64298662 |
Herpes simplex hepatitis | 9.99 | 9.42 | 9 | 181817 | 436 | 64316470 |
Haematotoxicity | 9.99 | 9.42 | 13 | 181813 | 12883 | 64304023 |
Gastrointestinal scarring | 9.98 | 9.42 | 7 | 181819 | 235 | 64316671 |
Tuberous sclerosis complex | 9.95 | 9.42 | 5 | 181821 | 89 | 64316817 |
Chest pain | 9.90 | 9.42 | 554 | 181272 | 235426 | 64081480 |
Oesophageal food impaction | 9.89 | 9.42 | 8 | 181818 | 334 | 64316572 |
Dislocation of vertebra | 9.89 | 9.42 | 25 | 181801 | 3099 | 64313807 |
Bacterial toxaemia | 9.88 | 9.42 | 6 | 181820 | 157 | 64316749 |
Blood glucose increased | 9.87 | 9.42 | 206 | 181620 | 97867 | 64219039 |
Skin ulcer | 9.83 | 9.42 | 78 | 181748 | 43896 | 64273010 |
Pituitary-dependent Cushing's syndrome | 9.83 | 9.42 | 3 | 181823 | 12 | 64316894 |
Dysgeusia | 9.82 | 9.42 | 85 | 181741 | 46962 | 64269944 |
Granulocytopenia | 9.77 | 9.42 | 9 | 181817 | 10431 | 64306475 |
Feeling hot | 9.76 | 9.42 | 182 | 181644 | 45481 | 64271425 |
Ocular procedural complication | 9.75 | 9.42 | 9 | 181817 | 450 | 64316456 |
Sinusitis | 9.75 | 9.42 | 504 | 181322 | 145424 | 64171482 |
Blood luteinising hormone decreased | 9.74 | 9.42 | 6 | 181820 | 161 | 64316745 |
Proteus infection | 9.74 | 9.42 | 17 | 181809 | 1626 | 64315280 |
Atrioventricular block complete | 9.73 | 9.42 | 16 | 181810 | 14402 | 64302504 |
Pharyngitis bacterial | 9.73 | 9.42 | 7 | 181819 | 245 | 64316661 |
Device difficult to use | 9.71 | 9.42 | 8 | 181818 | 9790 | 64307116 |
Fungaemia | 9.68 | 9.42 | 28 | 181798 | 3757 | 64313149 |
Hyperreflexia | 9.68 | 9.42 | 4 | 181822 | 7144 | 64309762 |
Perineal pain | 9.66 | 9.42 | 13 | 181813 | 990 | 64315916 |
Therapy interrupted | 9.56 | 9.42 | 27 | 181799 | 20009 | 64296897 |
Idiopathic intracranial hypertension | 9.55 | 9.42 | 22 | 181804 | 2571 | 64314335 |
Transient aphasia | 9.55 | 9.42 | 6 | 181820 | 167 | 64316739 |
Genital rash | 9.52 | 9.42 | 12 | 181814 | 857 | 64316049 |
Diaphragm muscle weakness | 9.52 | 9.42 | 6 | 181820 | 168 | 64316738 |
Botulism | 9.51 | 9.42 | 8 | 181818 | 353 | 64316553 |
White blood cell count increased | 9.47 | 9.42 | 130 | 181696 | 65884 | 64251022 |
Vaccination site inflammation | 9.45 | 9.42 | 4 | 181822 | 47 | 64316859 |
Cardiac failure chronic | 9.44 | 9.42 | 7 | 181819 | 9034 | 64307872 |
Quadriplegia | 9.42 | 9.42 | 24 | 181802 | 2989 | 64313917 |
None
Source | Code | Description |
---|---|---|
ATC | A01AC03 | ALIMENTARY TRACT AND METABOLISM STOMATOLOGICAL PREPARATIONS STOMATOLOGICAL PREPARATIONS Corticosteroids for local oral treatment |
ATC | A07EA02 | ALIMENTARY TRACT AND METABOLISM ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS INTESTINAL ANTIINFLAMMATORY AGENTS Corticosteroids acting locally |
ATC | C05AA01 | CARDIOVASCULAR SYSTEM VASOPROTECTIVES AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE Corticosteroids |
ATC | D07AA02 | DERMATOLOGICALS CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS CORTICOSTEROIDS, PLAIN Corticosteroids, weak (group I) |
ATC | D07BA04 | DERMATOLOGICALS CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS CORTICOSTEROIDS, COMBINATIONS WITH ANTISEPTICS Corticosteroids, weak, combinations with antiseptics |
ATC | D07CA01 | DERMATOLOGICALS CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS Corticosteroids, weak, combinations with antibiotics |
ATC | D07XA01 | DERMATOLOGICALS CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS CORTICOSTEROIDS, OTHER COMBINATIONS Corticosteroids, weak, other combinations |
ATC | H02AB09 | SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS CORTICOSTEROIDS FOR SYSTEMIC USE CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN Glucocorticoids |
ATC | R01AD60 | RESPIRATORY SYSTEM NASAL PREPARATIONS DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE Corticosteroids |
ATC | S01BA02 | SENSORY ORGANS OPHTHALMOLOGICALS ANTIINFLAMMATORY AGENTS Corticosteroids, plain |
ATC | S01BB01 | SENSORY ORGANS OPHTHALMOLOGICALS ANTIINFLAMMATORY AGENTS Corticosteroids and mydriatics in combination |
ATC | S01CA03 | SENSORY ORGANS OPHTHALMOLOGICALS ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION Corticosteroids and antiinfectives in combination |
ATC | S01CB03 | SENSORY ORGANS OPHTHALMOLOGICALS ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION Corticosteroids/antiinfectives/mydriatics in combination |
ATC | S02BA01 | SENSORY ORGANS OTOLOGICALS CORTICOSTEROIDS Corticosteroids |
ATC | S02CA03 | SENSORY ORGANS OTOLOGICALS CORTICOSTEROIDS AND ANTIINFECTIVES IN COMBINATION Corticosteroids and antiinfectives in combination |
ATC | S03CA04 | SENSORY ORGANS OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS CORTICOSTEROIDS AND ANTIINFECTIVES IN COMBINATION Corticosteroids and antiinfectives in combination |
FDA MoA | N0000175450 | Corticosteroid Hormone Receptor Agonists |
FDA EPC | N0000175576 | Corticosteroid |
MeSH PA | D000893 | Anti-Inflammatory Agents |
CHEBI has role | CHEBI:35472 | anti-inflammatory drugs |
CHEBI has role | CHEBI:49167 | anti-asthmatic drugs |
CHEBI has role | CHEBI:50857 | anti-allergic drugs |
CHEBI has role | CHEBI:75771 | Mus musculus metabolites |
CHEBI has role | CHEBI:77746 | Homo sapiens metabolite |
CHEBI has role | CHEBI:88188 | allergenic drug |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Disorder of musculoskeletal system | indication | 928000 | DOID:17 |
Cerebral edema | indication | 2032001 | |
Otitis externa | indication | 3135009 | |
Proctitis | indication | 3951002 | DOID:3127 |
Keratitis | indication | 5888003 | DOID:4677 |
Tinea pedis | indication | 6020002 | DOID:12403 |
Berylliosis | indication | 8247009 | DOID:10322 |
Psoriasis | indication | 9014002 | DOID:8893 |
Ankylosing spondylitis | indication | 9631008 | DOID:7147 |
Cyclitis | indication | 17657000 | |
Rheumatic heart disease | indication | 23685000 | |
Atopic dermatitis | indication | 24079001 | DOID:3310 |
Inflammatory bowel disease | indication | 24526004 | DOID:0050589 |
Multiple sclerosis | indication | 24700007 | DOID:2377 |
Severe adrenal insufficiency | indication | 24867002 | |
Sarcoidosis | indication | 31541009 | DOID:11335 |
Idiopathic thrombocytopenic purpura | indication | 32273002 | DOID:8924 |
Psoriasis with arthropathy | indication | 33339001 | |
Crohn's disease | indication | 34000006 | |
Tendinitis | indication | 34840004 | DOID:971 |
Erythema multiforme | indication | 36715001 | |
Contact dermatitis | indication | 40275004 | DOID:2773 |
Angioedema | indication | 41291007 | DOID:1558 |
Humoral hypercalcemia of malignancy | indication | 47709007 | |
Articular gout | indication | 48440001 | DOID:13189 |
Seborrheic dermatitis | indication | 50563003 | DOID:8741 |
Edema of larynx | indication | 51599000 | |
Chronic ulcerative proctitis | indication | 52231000 | |
Nephrotic syndrome | indication | 52254009 | DOID:1184 |
Lichen simplex chronicus | indication | 53891004 | |
Systemic lupus erythematosus | indication | 55464009 | DOID:9074 |
Allergic rhinitis | indication | 61582004 | |
Ulcerative colitis | indication | 64766004 | DOID:8577 |
Lรถffler's syndrome | indication | 64936001 | DOID:9503 |
Iritis | indication | 65074000 | DOID:1406 |
Pemphigus | indication | 65172003 | DOID:9182 |
Granuloma annulare | indication | 65508009 | DOID:3777 |
Tenosynovitis | indication | 67801009 | DOID:970 |
Blepharoconjunctivitis | indication | 68659002 | DOID:2456 |
Rheumatoid arthritis | indication | 69896004 | DOID:7148 |
Hemorrhoids | indication | 70153002 | DOID:9746 |
Transfusion reaction due to serum protein reaction | indication | 72284000 | |
Acquired thrombocytopenia | indication | 74576004 | DOID:11126 |
Iridocyclitis | indication | 77971008 | |
Thyroiditis | indication | 82119001 | DOID:7166 |
Bursitis | indication | 84017003 | DOID:2965 |
Tinea corporis | indication | 84849002 | |
Autoimmune disease | indication | 85828009 | |
Corneal abrasion | indication | 85848002 | |
Infective otitis externa | indication | 86981007 | DOID:9463 |
Infection by larvae of Trichinella spiralis | indication | 88264003 | |
Acne vulgaris | indication | 88616000 | |
Congenital hypoplastic anemia | indication | 88854002 | DOID:1339 |
Pruritus ani | indication | 90446007 | |
Corneal ulcer | indication | 91514001 | DOID:8463 |
Acute lymphoid leukemia | indication | 91857003 | DOID:9952 |
Dermatitis herpetiformis | indication | 111196000 | DOID:8505 |
Hodgkin's disease | indication | 118599009 | |
Non-Hodgkin's lymphoma | indication | 118601006 | |
Mycosis fungoides | indication | 118618005 | |
Uveitis | indication | 128473001 | DOID:13141 |
Aspiration pneumonitis | indication | 155597006 | |
Asthma | indication | 195967001 | DOID:2841 |
Discoid lupus erythematosus | indication | 200938002 | |
Plaque psoriasis | indication | 200965009 | |
Transplanted organ rejection | indication | 213148006 | |
Malignant otitis externa due to Pseudomonas aeruginosa | indication | 232230009 | |
Congenital adrenal hyperplasia | indication | 237751000 | |
Scalp psoriasis | indication | 238608008 | |
Punctate keratopathy | indication | 246936005 | |
Adrenogenital disorder | indication | 267395000 | DOID:0050811 |
Pruritus of genital organs | indication | 267802000 | |
Eruption of skin | indication | 271807003 | DOID:0050486 |
Infective blepharitis | indication | 312219000 | |
Bacterial keratitis | indication | 314557000 | |
Disorder of eye | indication | 371405004 | DOID:5614 |
Primary adrenocortical insufficiency | indication | 373662000 | |
Adrenal cortical hypofunction | indication | 386584007 | DOID:10493 |
Herpes zoster keratitis | indication | 397573005 | |
Rosacea | indication | 398909004 | DOID:8881 |
Tinea cruris | indication | 399029005 | |
Erythroderma | indication | 399992009 | |
Primary cutaneous T-cell lymphoma | indication | 400122007 | |
Recurrent herpes simplex labialis | indication | 402892009 | |
Autoimmune hemolytic anemia | indication | 413603009 | DOID:718 |
Synovitis | indication | 416209007 | DOID:2703 |
Aphthous ulcer of mouth | indication | 426965005 | DOID:9663 |
Allergic conjunctivitis | indication | 473460002 | DOID:11204 |
Post traumatic osteoarthritis | indication | 699262001 | |
Itching of ear | indication | 699392007 | |
Inflammatory dermatosis | indication | 703938007 | |
Post-Op Ocular Inflammation | indication | ||
Erythroblastic Anemia | indication | ||
Mastoidectomy Cavity Infections | indication | ||
Minor Bacterial Skin Infections | indication | ||
Staphylococcus Aureus Otitis Externa | indication | ||
Superficial Ocular Infection | indication | ||
Transfusion Reaction Urticaria | indication | ||
Synovitis due to Osteoarthritis | indication | ||
Diagnostic Test for Cushing's Syndrome | indication | ||
Gingival Disorders | indication | ||
Systemic Dermatomyositis | indication | ||
Chronic purulent otitis media | off-label use | 38394007 | DOID:14247 |
Respiratory distress syndrome in the newborn | off-label use | 46775006 | |
Adrenoleukodystrophy | off-label use | 65389002 | DOID:10588 |
Pityriasis simplex | off-label use | 200767005 | |
Allergic otitis externa | off-label use | 405821001 | |
Itching of skin | off-label use | 418363000 | |
Otitis Externa Eczema | off-label use | ||
Neonatal Bronchopulmonary Dysplasia | off-label use | ||
Congenital Pituitary Hypoplasia | off-label use | ||
Otitis Externa Seborrhea | off-label use | ||
Mycosis | contraindication | 3218000 | DOID:1564 |
Ocular hypertension | contraindication | 4210003 | DOID:9282 |
Herpes simplex keratitis | contraindication | 9389005 | |
Bacterial septicemia | contraindication | 10001005 | DOID:0040085 |
Inactive tuberculosis | contraindication | 11999007 | |
Peptic ulcer | contraindication | 13200003 | DOID:750 |
Measles | contraindication | 14189004 | DOID:8622 |
Esophagitis | contraindication | 16761005 | DOID:11963 |
Mood swings | contraindication | 18963009 | |
Infection of skin AND/OR subcutaneous tissue | contraindication | 19824006 | |
Cirrhosis of liver | contraindication | 19943007 | DOID:5082 |
Herpes zoster auricularis | contraindication | 21954000 | DOID:9210 |
Glaucoma | contraindication | 23986001 | DOID:1686 |
Abscess of intestine | contraindication | 24557004 | |
Acute tuberculosis | contraindication | 25629007 | |
Shock | contraindication | 27942005 | |
Herpes simplex dendritic keratitis | contraindication | 29943008 | |
Fungal infection of eye | contraindication | 31194008 | |
Bullous myringitis | contraindication | 33528003 | DOID:13791 |
Severe myopia | contraindication | 34187009 | |
Hyperthyroidism | contraindication | 34486009 | DOID:7998 |
Gastrointestinal fistula | contraindication | 37831005 | |
Hypertensive disorder | contraindication | 38341003 | DOID:10763 |
Infectious disease | contraindication | 40733004 | |
Hypothyroidism | contraindication | 40930008 | DOID:1459 |
Hypokalemia | contraindication | 43339004 | |
Chronic heart failure | contraindication | 48447003 | |
Tuberculosis of eye | contraindication | 49107007 | |
Duodenal ulcer disease | contraindication | 51868009 | DOID:1724 |
Perforation of tympanic membrane | contraindication | 60442001 | |
Osteoporosis | contraindication | 64859006 | DOID:11476 |
Psychotic disorder | contraindication | 69322001 | |
Diabetes mellitus | contraindication | 73211009 | DOID:9351 |
Hypopituitarism | contraindication | 74728003 | DOID:9406 |
Third degree burn injury | contraindication | 80247002 | |
Hyperglycemia | contraindication | 80394007 | DOID:4195 |
Decreased respiratory function | contraindication | 80954004 | |
Open-angle glaucoma | contraindication | 84494001 | DOID:1067 |
Krukenberg spindle | contraindication | 85430004 | |
Herpes simplex | contraindication | 88594005 | DOID:8566 |
Kidney disease | contraindication | 90708001 | DOID:557 |
Disorder of mucous membrane | contraindication | 95351003 | |
Bilateral cataracts | contraindication | 95722004 | |
Open wound | contraindication | 125643001 | |
Eye infection | contraindication | 128351009 | |
Seizure disorder | contraindication | 128613002 | |
Bacterial infection of eye | contraindication | 128984004 | |
Disorder of muscle | contraindication | 129565002 | DOID:423 |
Tuberculosis of ear | contraindication | 186269001 | |
Ophthalmic herpes simplex | contraindication | 186542001 | |
Heart block | contraindication | 233916004 | |
Anastomosis of intestine | contraindication | 235407009 | |
Disease of liver | contraindication | 235856003 | DOID:409 |
Condyloma acuminatum | contraindication | 240542006 | DOID:11168 |
Telangiectasia disorder | contraindication | 247479008 | |
Diverticulitis of gastrointestinal tract | contraindication | 271366000 | |
Injury of eye region | contraindication | 282752000 | |
Varicella-zoster virus infection | contraindication | 309465005 | |
Viral eye infection | contraindication | 312132001 | |
Viral ear infection | contraindication | 312137007 | |
Fungal ear infection | contraindication | 312148000 | |
Infective otitis media | contraindication | 312218008 | |
Skin irritation | contraindication | 367466007 | |
Vaccinia keratitis | contraindication | 397552005 | |
Gastric ulcer | contraindication | 397825006 | DOID:10808 |
Atrophoderma | contraindication | 399979006 | |
Peripheral vascular disease | contraindication | 400047006 | |
Blister | contraindication | 417237009 | |
Denuded skin | contraindication | 418242004 | |
Exposure to varicella | contraindication | 444453009 |
Species | Use | Relation |
---|---|---|
Cats | Acute otitis externa | Indication |
Cats | Chronic otitis externa | Indication |
Cats | Ear canker | Indication |
Cats | Inflammatory conditions of the external ear canal | Indication |
Cats | Allergy | Indication |
Cats | Infectious skin conditions | Indication |
Cats | Traumatic skin conditions | Indication |
Cats | Prevention of bacterial infections in superficial wounds | Indication |
Cats | Prevention of bacterial infections in cuts | Indication |
Cats | Prevention of bacterial infections in abrasions | Indication |
Cats | Allergic dermatoses | Indication |
Cats | Infections associated with minor burns and wounds | Indication |
Cats | Nonspecific pruritus | Indication |
Dogs | Acute otitis externa | Indication |
Dogs | Chronic otitis externa | Indication |
Dogs | Ear canker | Indication |
Dogs | Inflammatory conditions of the external ear canal | Indication |
Dogs | Allergy | Indication |
Dogs | Infectious skin conditions | Indication |
Dogs | Traumatic skin conditions | Indication |
Dogs | Prevention of bacterial infections in superficial wounds | Indication |
Dogs | Prevention of bacterial infections in cuts | Indication |
Dogs | Prevention of bacterial infections in abrasions | Indication |
Dogs | Allergic dermatoses | Indication |
Dogs | Infections associated with minor burns and wounds | Indication |
Dogs | Nonspecific pruritus | Indication |
Horses | No Use Class Stated Or Implied | Indication |
Product | Applicant | Ingredients |
---|---|---|
Liqua-Cortril Spray, Terra-Cortril Spray | Zoetis Inc. | 2 |
Cortisporin Veterinary Ophthalmic Ointment | Intervet Inc. | 4 |
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 12.31 | acidic |
pKa2 | 13.65 | acidic |
Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Patent number | Patent expiration date | Patent use |
---|---|---|---|---|---|---|---|---|---|---|
5%;1% | XERESE | BAUSCH | N022436 | July 31, 2009 | RX | CREAM | TOPICAL | 7223387 | Nov. 13, 2022 | COMBINATION PRODUCT FOR THE EARLY TREATMENT OF RECURRENT HERPES LABIALIS (COLD SORES) TO REDUCE THE LIKELIHOOD OF ULCERATIVE COLD SORES AND TO SHORTEN THE LESION HEALING TIME IN ADULTS AND CHILDREN (6 YEARS OF AGE AND OLDER) |
5%;1% | XERESE | BAUSCH | N022436 | July 31, 2009 | RX | CREAM | TOPICAL | 7223387 | Nov. 13, 2022 | NEW COMBINATION PRODUCT FOR THE EARLY TREATMENT OF RECURRENT HERPES LABIALIS (COLD SORES) TO REDUCE THE LIKELIHOOD OF ULCERATIVE COLD SORES AND TO SHORTEN THE LESION HEALING TIME IN ADULTS AND ADOLESCENTS (12 YEARS OF AGE AND OLDER) |
0.5MG | ALKINDI SPRINKLE | ETON | N213876 | Sept. 29, 2020 | RX | GRANULE | ORAL | 9717740 | Nov. 19, 2032 | TREATMENT OF ADRENAL INSUFFICIENCY |
1MG | ALKINDI SPRINKLE | ETON | N213876 | Sept. 29, 2020 | RX | GRANULE | ORAL | 9717740 | Nov. 19, 2032 | TREATMENT OF ADRENAL INSUFFICIENCY |
2MG | ALKINDI SPRINKLE | ETON | N213876 | Sept. 29, 2020 | RX | GRANULE | ORAL | 9717740 | Nov. 19, 2032 | TREATMENT OF ADRENAL INSUFFICIENCY |
5MG | ALKINDI SPRINKLE | ETON | N213876 | Sept. 29, 2020 | RX | GRANULE | ORAL | 9717740 | Nov. 19, 2032 | TREATMENT OF ADRENAL INSUFFICIENCY |
0.5MG | ALKINDI SPRINKLE | ETON | N213876 | Sept. 29, 2020 | RX | GRANULE | ORAL | 9675559 | Jan. 10, 2033 | TREATMENT OF ADRENAL INSUFFICIENCY |
1MG | ALKINDI SPRINKLE | ETON | N213876 | Sept. 29, 2020 | RX | GRANULE | ORAL | 9675559 | Jan. 10, 2033 | TREATMENT OF ADRENAL INSUFFICIENCY |
2MG | ALKINDI SPRINKLE | ETON | N213876 | Sept. 29, 2020 | RX | GRANULE | ORAL | 9675559 | Jan. 10, 2033 | TREATMENT OF ADRENAL INSUFFICIENCY |
5MG | ALKINDI SPRINKLE | ETON | N213876 | Sept. 29, 2020 | RX | GRANULE | ORAL | 9675559 | Jan. 10, 2033 | TREATMENT OF ADRENAL INSUFFICIENCY |
0.5MG | ALKINDI SPRINKLE | ETON | N213876 | Sept. 29, 2020 | RX | GRANULE | ORAL | 9649280 | May 12, 2034 | TREATMENT OF ADRENAL INSUFFICIENCY |
1MG | ALKINDI SPRINKLE | ETON | N213876 | Sept. 29, 2020 | RX | GRANULE | ORAL | 9649280 | May 12, 2034 | TREATMENT OF ADRENAL INSUFFICIENCY |
2MG | ALKINDI SPRINKLE | ETON | N213876 | Sept. 29, 2020 | RX | GRANULE | ORAL | 9649280 | May 12, 2034 | TREATMENT OF ADRENAL INSUFFICIENCY |
5MG | ALKINDI SPRINKLE | ETON | N213876 | Sept. 29, 2020 | RX | GRANULE | ORAL | 9649280 | May 12, 2034 | TREATMENT OF ADRENAL INSUFFICIENCY |
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Glucocorticoid receptor | Nuclear hormone receptor | AGONIST | EC50 | 8.50 | WOMBAT-PK | CHEMBL | |||
Annexin A1 | Cytosolic other | WOMBAT-PK | |||||||
Mineralocorticoid receptor | Nuclear hormone receptor | AGONIST | IC50 | 9.95 | IUPHAR | ||||
Nitric oxide synthase, inducible | Enzyme | IC50 | 8 | WOMBAT-PK | |||||
Corticosteroid-binding globulin | Secreted | Ki | 7.88 | WOMBAT-PK | |||||
Sex hormone-binding globulin | Secreted | Kd | 6.20 | CHEMBL | |||||
Glucocorticoid receptor | Transcription factor | Kd | 7.37 | CHEMBL |
ID | Source |
---|---|
4017941 | VUID |
N0000146291 | NUI |
D00088 | KEGG_DRUG |
4017941 | VANDF |
C0020268 | UMLSCUI |
CHEBI:17650 | CHEBI |
HCY | PDB_CHEM_ID |
CHEMBL389621 | ChEMBL_ID |
DB00741 | DRUGBANK_ID |
D006854 | MESH_DESCRIPTOR_UI |
5754 | PUBCHEM_CID |
2868 | IUPHAR_LIGAND_ID |
38 | INN_ID |
WI4X0X7BPJ | UNII |
202643 | RXNORM |
174 | MMSL |
2500 | MMSL |
4837 | MMSL |
d00254 | MMSL |
002147 | NDDF |
16602005 | SNOMEDCT_US |
396458002 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
CORTEF | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0009-0012 | TABLET | 5 mg | ORAL | NDA | 15 sections |
CORTEF | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0009-0031 | TABLET | 10 mg | ORAL | NDA | 15 sections |
CORTEF | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0009-0044 | TABLET | 20 mg | ORAL | NDA | 15 sections |
CIPROHC | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0065-8531 | SUSPENSION | 10 mg | AURICULAR (OTIC) | NDA | 16 sections |
CIPROHC | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0078-0855 | SUSPENSION/ DROPS | 10 mg | AURICULAR (OTIC) | NDA | 16 sections |
Aquanil HC | HUMAN OTC DRUG LABEL | 1 | 0096-0732 | LOTION | 0.01 g | TOPICAL | OTC monograph not final | 10 sections |
Good Sense Anti Itch | HUMAN OTC DRUG LABEL | 1 | 0113-0471 | OINTMENT | 1 g | TOPICAL | OTC monograph not final | 13 sections |
good sense anti itch | HUMAN OTC DRUG LABEL | 1 | 0113-0541 | CREAM | 1 g | TOPICAL | OTC monograph not final | 13 sections |
basic care hydrocortisone | HUMAN OTC DRUG LABEL | 1 | 0113-0793 | CREAM | 1 g | TOPICAL | OTC monograph not final | 13 sections |
Good Sense Anti Itch | HUMAN OTC DRUG LABEL | 1 | 0113-0973 | CREAM | 1 g | TOPICAL | OTC monograph not final | 13 sections |
good sense anti itch | HUMAN OTC DRUG LABEL | 1 | 0113-1369 | CREAM | 1 g | TOPICAL | OTC monograph not final | 13 sections |
Basic Case Hydrocortisone Anti-Itch | HUMAN OTC DRUG LABEL | 1 | 0113-7006 | CREAM | 1 g | TOPICAL | OTC monograph not final | 13 sections |
basic care hydrocortisone | HUMAN OTC DRUG LABEL | 1 | 0113-7369 | CREAM | 1 g | TOPICAL | OTC monograph not final | 13 sections |
HYDROCORTISONE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0115-1696 | TABLET | 5 mg | ORAL | ANDA | 14 sections |
HYDROCORTISONE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0115-1697 | TABLET | 10 mg | ORAL | ANDA | 14 sections |
HYDROCORTISONE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0115-1700 | TABLET | 20 mg | ORAL | ANDA | 14 sections |
HYDROCORTISONE | HUMAN OTC DRUG LABEL | 1 | 0168-0014 | CREAM | 5 mg | TOPICAL | OTC monograph final | 9 sections |
hydrocortisone | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0168-0015 | CREAM | 10 mg | TOPICAL | ANDA | 19 sections |
HYDROCORTISONE | HUMAN OTC DRUG LABEL | 1 | 0168-0016 | OINTMENT | 5 mg | TOPICAL | OTC monograph final | 9 sections |
Hydrocortisone | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0168-0020 | OINTMENT | 10 mg | TOPICAL | ANDA | 18 sections |
Hydrocortisone | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0168-0080 | CREAM | 25 mg | TOPICAL | ANDA | 17 sections |
Hydrocortisone | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0168-0146 | OINTMENT | 25 mg | TOPICAL | ANDA | 17 sections |
Hydrocortisone | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0168-0288 | LOTION | 25 mg | TOPICAL | ANDA | 18 sections |
Texacort | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0178-0455 | SOLUTION | 25 mg | TOPICAL | ANDA | 20 sections |
KAISER PERMANENTEHydrocortisone | HUMAN OTC DRUG LABEL | 1 | 0179-8711 | OINTMENT | 1 g | TOPICAL | OTC monograph not final | 15 sections |
Xerese | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0187-5104 | CREAM | 10 mg | TOPICAL | NDA | 26 sections |
Alacort | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0316-0126 | CREAM | 10 mg | TOPICAL | ANDA | 19 sections |
Alacort | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0316-0128 | CREAM | 25 mg | TOPICAL | ANDA | 19 sections |
Hydrocortisone | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0316-0186 | CREAM | 10 mg | TOPICAL | ANDA | 19 sections |
Hydrocortisone | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0316-0193 | CREAM | 25 mg | TOPICAL | ANDA | 19 sections |