formocortal 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
corticosteroids, except prednisolone derivatives 3245 2825-60-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • formocortal
  • cutisterol
  • deflamene
  • fluoformylon
  • fluoroformylon
  • fluoroformylone
  • Molecular weight: 569.06
  • Formula: C29H38ClFO8
  • CLOGP: 3.56
  • LIPINSKI: 1
  • HAC: 8
  • HDO: 1
  • TPSA: 108.36
  • ALOGS: -4.81
  • ROTB: 8

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2B,AXL,BRAF,CAMK2D,CDK5,CDK9,EIF2AK3,EPHB4,ERBB2,GRK2,ITK,MAPK10,MAPK7,NTRK2,PDK1,PDK2,PDK4,PIK3CB,PRKDC,STK33,TEK 21
kinase-selectivity-class GRK2 1
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC S01BA12 SENSORY ORGANS
OPHTHALMOLOGICALS
ANTIINFLAMMATORY AGENTS
Corticosteroids, plain
CHEBI has role CHEBI:66981 ophthalmology drug

Related Drugs by ATC class:

S01BA Corticosteroids, plain 15 drugs
alclometasone dipropionatebetamethasoneclobetasol propionateclobetasone butyratedesonidedexamethasonedifluprednatefluocinolone acetonidefluorometholonehydrocortisoneloteprednol etabonatemedrysone show all 15 →

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 11.02 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D04244 KEGG_DRUG
C3652565 UMLSCUI
CHEBI:135834 CHEBI
CHEMBL1989587 ChEMBL_ID
DB13664 DRUGBANK_ID
2289 INN_ID
8E21R0Z4M5 UNII
289085 PUBCHEM_CID

Pharmaceutical products:

None