cloprednol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
prednisone and prednisolone derivatives 709 5251-34-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • cloprednol
  • cloprednole
  • cloradryn
relative anti-inflammatory potency twice prednisolone; synthetic glucocorticoid; structure
  • Molecular weight: 392.88
  • Formula: C21H25ClO5
  • CLOGP: 1.52
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 3
  • TPSA: 94.83
  • ALOGS: -3.60
  • ROTB: 2

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC H02AB14 SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
CORTICOSTEROIDS FOR SYSTEMIC USE
CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
Glucocorticoids

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.13 acidic
pKa2 12.77 acidic
pKa3 13.22 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D03561 KEGG_DRUG
21285 RXNORM
C0055936 UMLSCUI
CHEBI:135619 CHEBI
CHEMBL1697832 ChEMBL_ID
DB13843 DRUGBANK_ID
C011731 MESH_SUPPLEMENTAL_RECORD_UI
5284535 PUBCHEM_CID
3566 INN_ID
SYP56O3GJG UNII
006002 NDDF

Pharmaceutical products:

None