alclometasone dipropionate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4493 | 66734-13-2 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| Dec. 14, 1982 | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | D07AB10 | DERMATOLOGICALS CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS CORTICOSTEROIDS, PLAIN Corticosteroids, moderately potent (group II) |
| ATC | S01BA10 | SENSORY ORGANS OPHTHALMOLOGICALS ANTIINFLAMMATORY AGENTS Corticosteroids, plain |
| FDA MoA | N0000175450 | Corticosteroid Hormone Receptor Agonists |
| FDA EPC | N0000175576 | Corticosteroid |
| MeSH PA | D000893 | Anti-Inflammatory Agents |
| MeSH PA | D005938 | Glucocorticoids |
| MeSH PA | D006728 | Hormones |
| CHEBI has role | CHEBI:35472 | anti-inflammatory drugs |
| CHEBI has role | CHEBI:59683 | antipruritic drugs |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Atopic dermatitis | indication | 24079001 | DOID:3310 |
| Contact dermatitis | indication | 40275004 | DOID:2773 |
| Seborrheic dermatitis | indication | 50563003 | DOID:8741 |
| Lichen simplex chronicus | indication | 53891004 | |
| Granuloma annulare | indication | 65508009 | DOID:3777 |
| Pruritus ani | indication | 90446007 | |
| Discoid lupus erythematosus | indication | 200938002 | |
| Plaque psoriasis | indication | 200965009 | |
| Scalp psoriasis | indication | 238608008 | |
| Pruritus of genital organs | indication | 267802000 | |
| Eruption of skin | indication | 271807003 | DOID:0050486 |
| Primary cutaneous T-cell lymphoma | indication | 400122007 | |
| Hypopituitarism | contraindication | 74728003 | DOID:9406 |
| Hyperglycemia | contraindication | 80394007 | DOID:4195 |
| Skin striae | contraindication | 201066002 | |
| Telangiectasia disorder | contraindication | 247479008 | |
| Atrophoderma | contraindication | 399979006 |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 13.17 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Glucocorticoid receptor | Nuclear hormone receptor | AGONIST | CHEMBL | CHEMBL |
External reference:
| ID | Source |
|---|---|
| D01820 | KEGG_DRUG |
| 4019596 | VUID |
| N0000147692 | NUI |
| 4018899 | VANDF |
| 4019596 | VANDF |
| CHEBI:31184 | CHEBI |
| CHEBI:53776 | CHEBI |
| CHEMBL1200989 | ChEMBL_ID |
| C021137 | MESH_SUPPLEMENTAL_RECORD_UI |
| S56PQL4N1V | UNII |
| DB00240 | DRUGBANK_ID |
| 108088 | RXNORM |
| 4129 | MMSL |
| 59682 | MMSL |
| 902 | MMSL |
| 002204 | NDDF |
| 004951 | NDDF |
| 116570009 | SNOMEDCT_US |
| 38684009 | SNOMEDCT_US |
| 395956000 | SNOMEDCT_US |
| C0051113 | UMLSCUI |
| C0360534 | UMLSCUI |
| 636374 | PUBCHEM_CID |
| 4616 | INN_ID |
| 67452-97-5 | SECONDARY_CAS_RN |
| 5311000 | PUBCHEM_CID |
| 136H45TB7B | UNII |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Alclometasone Dipropionate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0168-0263 | CREAM | 0.50 mg | TOPICAL | ANDA | 20 sections |
| Alclometasone Dipropionate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0168-0264 | OINTMENT | 0.50 mg | TOPICAL | ANDA | 20 sections |
| Alclometasone dipropionate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51672-1306 | CREAM | 0.50 mg | TOPICAL | ANDA | 22 sections |
| Alclometasone Dipropionate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51672-1316 | OINTMENT | 0.50 mg | TOPICAL | ANDA | 22 sections |
| Alclometasone Dipropionate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 54868-2861 | CREAM | 0.50 mg | TOPICAL | ANDA | 22 sections |
| Alclometasone Dipropionate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 68462-299 | OINTMENT | 0.50 mg | TOPICAL | ANDA | 22 sections |
| Alclometasone Dipropionate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 68462-300 | CREAM | 0.50 mg | TOPICAL | ANDA | 22 sections |