octenidine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
alpha-2 adrenoreceptor agonists 3394 71251-02-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • octenidine
  • Molecular weight: 550.92
  • Formula: C36H62N4
  • CLOGP: 9.12
  • LIPINSKI: 2
  • HAC: 4
  • HDO: 0
  • TPSA: 31.20
  • ALOGS: -7.33
  • ROTB: 25

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,ACVRL1,AKT1,AKT2,AKT3,ALK,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GSK3B,IKBKB,ITK,JAK1,JAK2,JAK3,MAP2K6,MAP3K21,MAP3K7,MAP4K1,MAPK10,MAPK12,MAPK7,MAPK9,MAPKAPK2,MET,MTOR,NTRK2,PAK4,PDK1,PDK2,PDK4,PDPK1,PIK3CB,PIK3CG,PIM2,PLK1,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ULK1,ZAP70 61
kinase-selectivity-class AKT2,AXL,CDK4,EIF2AK3,EPHB4,GRK2,INSR,MAP2K6,MAPK12,PLK1,PLK2,PLK3,PLK4,STK33,TEK 15
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A01AB24 ALIMENTARY TRACT AND METABOLISM
STOMATOLOGICAL PREPARATIONS
STOMATOLOGICAL PREPARATIONS
Antiinfectives and antiseptics for local oral treatment
ATC D08AJ57 DERMATOLOGICALS
ANTISEPTICS AND DISINFECTANTS
ANTISEPTICS AND DISINFECTANTS
Quaternary ammonium compounds
ATC G01AX66 GENITO URINARY SYSTEM AND SEX HORMONES
GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
Other antiinfectives and antiseptics
ATC R02AA21 RESPIRATORY SYSTEM
THROAT PREPARATIONS
THROAT PREPARATIONS
Antiseptics
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000891 Anti-Infective Agents, Local
CHEBI has role CHEBI:35441 antiinfective agent

Related Drugs by ATC class:

A01AB Antiinfectives and antiseptics for local oral treatment 22 drugs
amphotericin Bbenzoxonium chloridecetylpyridiniumchlorhexidinechlortetracyclineclotrimazoledomiphendoxycyclinehexetidinehydrogen peroxidemepartricinmetronidazole show all 22 →
D08AJ Quaternary ammonium compounds 9 drugs
benzalkoniumbenzethoniumbenzoxonium chloridecetrimidecetrimoniumcetylpyridiniumdecamethoxinedidecyldimethylammonium chloridedodeclonium bromide
G01AX Other antiinfectives and antiseptics 10 drugs
ciclopiroxclodantoinfurazolidonehexetidineinosinemethylrosanilinenifuratelpolicresulenpovidone-iodineprotiofate
R02AA Antiseptics 15 drugs
ambazonebenzalkoniumbenzethoniumcetrimoniumcetylpyridiniumchlorhexidinechlorquinaldoldequaliniumdichlorobenzyl alcoholeuflavinehexamidinehexylresorcinol show all 15 →

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 13.5 Basic
pKa2 13.5 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D08289 KEGG_DRUG
C0069351 UMLSCUI
CHEBI:135826 CHEBI
CHEMBL1199480 ChEMBL_ID
DB12624 DRUGBANK_ID
C034213 MESH_SUPPLEMENTAL_RECORD_UI
4829 INN_ID
OZE0372S5A UNII
51167 PUBCHEM_CID
2119240 RXNORM
014415 NDDF
430477008 SNOMEDCT_US

Pharmaceutical products:

None