cetrimide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4360	8044-71-1

Description:

Molecule

Description

Synonyms:

cetrimide
cetavlon
quammonium

Molecular weight:
Formula: C4H11BrN(CH3)11,13,15
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA:
ALOGS:
ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Sleep disorder due to general medical condition, insomnia type	85.82	57.32	43	2733	52174	63434072
Muscle injury	85.02	57.32	46	2730	65299	63420947
Folliculitis	81.86	57.32	46	2730	70271	63415975
Irritable bowel syndrome	75.08	57.32	46	2730	82366	63403880
Ill-defined disorder	67.81	57.32	43	2733	81712	63404534
Impaired healing	65.89	57.32	46	2730	102496	63383750
Lower respiratory tract infection	59.67	57.32	48	2728	132259	63353987

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Muscle injury	105.07	77.78	45	2708	48516	79693119
Sleep disorder due to general medical condition, insomnia type	99.65	77.78	42	2711	43514	79698121
Folliculitis	99.39	77.78	45	2708	55335	79686300
Irritable bowel syndrome	94.37	77.78	45	2708	62196	79679439
Ill-defined disorder	80.12	77.78	41	2712	65834	79675801
Impaired healing	79.82	77.78	45	2708	87610	79654025

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	D08AJ04	DERMATOLOGICALS ANTISEPTICS AND DISINFECTANTS ANTISEPTICS AND DISINFECTANTS Quaternary ammonium compounds
ATC	D11AC01	DERMATOLOGICALS OTHER DERMATOLOGICAL PREPARATIONS OTHER DERMATOLOGICAL PREPARATIONS Medicated shampoos
CHEBI has role	CHEBI:27780	Detergents
CHEBI has role	CHEBI:35195	surfactant
MeSH PA	D000890	Anti-Infective Agents
MeSH PA	D000891	Anti-Infective Agents, Local

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Dynamin-1	Structural	Q05193	DYN1_HUMAN		IC50	5.24		CHEMBL

External reference:

ID	Source
D02164	KEGG_DRUG
C0950191	UMLSCUI
CHEBI:3567	CHEBI
CHEMBL1180003	ChEMBL_ID
CHEMBL5219790	ChEMBL_ID
CHEMBL5219942	ChEMBL_ID
5157	INN_ID
24QSH2NL8N	UNII
14250	PUBCHEM_CID
288088	RXNORM
003518	NDDF
333179001	SNOMEDCT_US
395895003	SNOMEDCT_US
D000077286	MESH_DESCRIPTOR_UI

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Derma Wound-Eaz	HUMAN OTC DRUG LABEL	1	82160-696	CREAM	5 mg	TOPICAL	unapproved drug other	15 sections