cetrimonium 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
quaternary ammonium compounds 3082 57-09-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • cetrimonium bromide
  • cetrimonium
Cetyltrimethylammonium compound whose salts and derivatives are used primarily as topical antiseptics.
  • Molecular weight: 284.55
  • Formula: C19H42N
  • CLOGP: 2.68
  • LIPINSKI: 0
  • HAC: 1
  • HDO: 0
  • TPSA:
  • ALOGS: -7.79
  • ROTB: 15

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC D08AJ02 DERMATOLOGICALS
ANTISEPTICS AND DISINFECTANTS
ANTISEPTICS AND DISINFECTANTS
Quaternary ammonium compounds
ATC R02AA17 RESPIRATORY SYSTEM
THROAT PREPARATIONS
THROAT PREPARATIONS
Antiseptics
CHEBI has role CHEBI:27780 Detergents
CHEBI has role CHEBI:35195 surfactant
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000891 Anti-Infective Agents, Local

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Dynamin-1 Structural IC50 5.36 CHEMBL

External reference:

IDSource
4020954 VUID
N0000184202 NUI
D03454 KEGG_DRUG
4020954 VANDF
C0055151 UMLSCUI
CHEBI:39561 CHEBI
CHEMBL1183605 ChEMBL_ID
CHEMBL307346 ChEMBL_ID
DB01718 DRUGBANK_ID
Z7FF1XKL7A UNII
2681 PUBCHEM_CID
20614 RXNORM
NOCODE MMSL
004334 NDDF
004335 NDDF
D000077286 MESH_DESCRIPTOR_UI
16A PDB_CHEM_ID
2036 INN_ID
6899-10-1 SECONDARY_CAS_RN

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Dr. Zheng bacteriostatic solution HUMAN OTC DRUG LABEL 1 42091-001 LIQUID 0.13 mg EXTRACORPOREAL unapproved drug other 7 sections