desoximetasone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
prednisone and prednisolone derivatives 819 382-67-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • desoximetasone
  • deoxymethasone
  • desoximethasone
  • desoxymetasone
  • desoxymethasone
A topical anti-inflammatory glucocorticoid used in DERMATOSES, skin allergies, PSORIASIS, etc.
  • Molecular weight: 376.47
  • Formula: C22H29FO4
  • CLOGP: 2.41
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 2
  • TPSA: 74.60
  • ALOGS: -4.08
  • ROTB: 2
  • Status: OFP
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2B,BRAF,CAMK2D,CDK5,EIF2AK3,ERBB2,GRK2,ITK,MAPK10,NTRK2,PDK1,PDK2,PDK4,PRKDC,TEK 15
kinase-selectivity-class EIF2AK3,GRK2,MAP2K6 3
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

DateAgencyCompanyOrphan
Feb. 28, 1977 FDA TARO PHARMS NORTH

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Pemphigus 3957.85 57.05 5833 378778 321031 89922805
Glossodynia 3748.77 57.05 5640 378971 316139 89927697
Systemic lupus erythematosus 3687.36 57.05 5963 378648 355933 89887903
Hand deformity 3435.91 57.05 5184 379427 291178 89952658
Wound 2903.33 57.05 4859 379752 298121 89945715
Pericarditis 2752.72 57.05 4455 380156 265696 89978140
Anti-cyclic citrullinated peptide antibody positive 2559.32 57.05 4009 380602 232424 90011412
Synovitis 2503.60 57.05 4778 379833 324974 89918862
Arthropathy 2474.67 57.05 5053 379558 361189 89882647
Alopecia 2362.16 57.05 5948 378663 489123 89754713
Swelling 2320.85 57.05 5335 379276 413723 89830113
Discomfort 2290.52 57.05 4142 380469 270193 89973643
Duodenal ulcer perforation 2281.12 57.05 3670 380941 217618 90026218
Abdominal discomfort 2236.17 57.05 5696 378915 471632 89772204
Helicobacter infection 2150.53 57.05 3623 380988 223227 90020609
Contraindicated product administered 2063.75 57.05 4334 380277 315805 89928031
Hepatic enzyme increased 1609.58 57.05 4230 380381 356506 89887330
Infusion related reaction 1463.75 57.05 4482 380129 412298 89831538
Folliculitis 1462.48 57.05 2891 381720 201462 90042374
Drug intolerance 1458.72 57.05 4690 379921 442901 89800935
Rheumatoid factor positive 1401.71 57.05 2569 382042 169081 90074755
Rheumatic fever 1343.86 57.05 2365 382246 150756 90093080
Acute kidney injury 1340.72 57.05 3 384608 320384 89923452
Muscle injury 1256.20 57.05 2493 382118 174161 90069675
Irritable bowel syndrome 1244.41 57.05 2730 381881 204718 90039118
Maternal exposure during pregnancy 1226.12 57.05 3832 380779 356231 89887605
Blister 1207.99 57.05 3060 381551 251938 89991898
Type 2 diabetes mellitus 1177.68 57.05 2638 381973 200606 90043230
Impaired healing 1174.07 57.05 2872 381739 231327 90012509
Toxicity to various agents 1170.29 57.05 9 384602 287837 89955999
Hypersensitivity 1152.91 57.05 4386 380225 450291 89793545
Joint swelling 1130.66 57.05 4674 379937 498626 89745210
Psoriatic arthropathy 1117.93 57.05 2775 381836 225560 90018276
Drug interaction 1090.24 57.05 16 384595 276437 89967399
Death 1055.55 57.05 314 384297 456237 89787599
Sleep disorder due to general medical condition, insomnia type 1014.79 57.05 1898 382713 126796 90117040
Anaemia 1009.11 57.05 148 384463 352654 89891182
Swollen joint count increased 982.22 57.05 1723 382888 109483 90134353
Liver injury 981.20 57.05 2208 382403 168359 90075477
Blood cholesterol increased 974.05 57.05 2486 382125 205526 90038310
Therapeutic product effect decreased 929.17 57.05 2938 381673 274633 89969203
Constipation 917.62 57.05 72 384539 280323 89963513
Hypotension 906.62 57.05 147 384464 325250 89918586
Fibromyalgia 892.92 57.05 2394 382217 203875 90039961
Product use issue 892.26 57.05 3251 381360 326668 89917168
Treatment failure 875.75 57.05 3058 381553 300870 89942966
Ill-defined disorder 830.72 57.05 2176 382435 182715 90061121
Fall 817.15 57.05 519 384092 481291 89762545
Stomatitis 800.82 57.05 2775 381836 271923 89971913
Neutropenia 782.35 57.05 42 384569 224862 90018974
Urinary tract infection 779.20 57.05 172 384439 305460 89938376
Nausea 754.25 57.05 2322 382289 1107994 89135842
Product dose omission issue 743.88 57.05 164 384447 291523 89952313
Injury 737.68 57.05 2172 382439 195177 90048659
Lower respiratory tract infection 725.98 57.05 2527 382084 248132 89995704
Cough 725.53 57.05 329 384282 368633 89875203
Dehydration 724.30 57.05 22 384589 194425 90049411
Somnolence 721.19 57.05 41 384570 209043 90034793
Sepsis 706.20 57.05 11 384600 179803 90064033
General physical health deterioration 683.66 57.05 3151 381460 351964 89891872
Febrile neutropenia 616.34 57.05 11 384600 158338 90085498
Haemoglobin decreased 615.53 57.05 15 384596 161941 90081895
Back pain 615.41 57.05 288 384323 316887 89926949
Facet joint syndrome 600.70 57.05 1305 383306 97084 90146752
Mobility decreased 576.58 57.05 2348 382263 248386 89995450
Intentional product use issue 556.89 57.05 2103 382508 214789 90029047
Erythema 537.73 57.05 153 384458 229093 90014743
Joint range of motion decreased 534.64 57.05 1522 383089 134121 90109715
Tremor 531.36 57.05 29 384582 153144 90090692
Gastrointestinal disorder 527.51 57.05 2323 382288 254364 89989472
Seizure 526.06 57.05 30 384581 152599 90091237
Lip dry 519.91 57.05 1252 383359 99703 90144133
Renal failure 518.74 57.05 7 384604 131000 90112836
Pulmonary embolism 513.65 57.05 8 384603 130812 90113024
Musculoskeletal stiffness 498.08 57.05 2531 382080 294001 89949835
Cerebrovascular accident 491.78 57.05 6 384605 123527 90120309
Thrombocytopenia 479.09 57.05 145 384466 208580 90035256
Injection site pain 475.63 57.05 82 384529 173617 90070219
Respiratory failure 474.82 57.05 5 384606 118413 90125423
Hip arthroplasty 472.20 57.05 1017 383594 75191 90168645
Deep vein thrombosis postoperative 471.30 57.05 973 383638 69836 90174000
Syncope 470.05 57.05 22 384589 132641 90111195
Feeling abnormal 462.22 57.05 77 384534 167158 90076678
Hyperhidrosis 460.07 57.05 30 384581 136275 90107561
Pain 441.64 57.05 6289 378322 990052 89253784
Grip strength decreased 437.46 57.05 1111 383500 91465 90152371
COVID-19 434.16 57.05 93 384518 168750 90075086
Cardiac failure 432.86 57.05 6 384605 109490 90134346
Neuropathy peripheral 426.68 57.05 43 384568 136927 90106909
Breast cancer stage III 423.79 57.05 1037 383574 83410 90160426
C-reactive protein abnormal 420.27 57.05 1343 383268 126086 90117750
Infection 418.77 57.05 2800 381811 359294 89884542
Malignant neoplasm progression 417.60 57.05 7 384604 106863 90136973
Knee arthroplasty 409.51 57.05 1014 383597 82168 90161668
Contusion 404.15 57.05 2119 382492 249097 89994739
Autoimmune disorder 399.64 57.05 956 383655 75788 90168048
Myalgia 397.65 57.05 124 384487 175001 90068835
White blood cell count decreased 394.65 57.05 110 384501 166999 90076837
Diarrhoea 394.02 57.05 2357 382254 936833 89307003
Wound infection 387.60 57.05 1161 383450 105241 90138595
Cardiac failure congestive 387.59 57.05 6 384605 98688 90145148
Dysphagia 387.10 57.05 22 384589 112256 90131580
Blood creatinine increased 382.88 57.05 10 384601 101376 90142460
Hypercholesterolaemia 381.90 57.05 1116 383495 99776 90144060
Chest discomfort 381.70 57.05 64 384547 138301 90105535
Renal impairment 375.04 57.05 17 384594 105404 90138432
Platelet count decreased 367.71 57.05 68 384543 136901 90106935
Palpitations 364.66 57.05 69 384542 136659 90107177
Peripheral venous disease 358.53 57.05 970 383641 82951 90160885
Gastrointestinal haemorrhage 356.49 57.05 5 384606 90243 90153593
Live birth 350.71 57.05 927 383684 78180 90165656
Vision blurred 347.79 57.05 33 384578 110260 90133576
Flushing 344.90 57.05 6 384605 88485 90155351
Bursitis 344.64 57.05 1285 383326 130369 90113467
Sleep disorder 334.79 57.05 1694 382917 196336 90047500
Pulmonary fibrosis 332.83 57.05 1109 383502 106394 90137442
Gait inability 327.19 57.05 1360 383251 145096 90098740
Confusional state 323.22 57.05 2768 381843 383437 89860399
Obesity 313.03 57.05 1073 383538 104434 90139402
Rash 312.83 57.05 4925 379686 791175 89452661
Dislocation of vertebra 309.67 57.05 714 383897 55254 90188582
Adjustment disorder with depressed mood 309.61 57.05 720 383891 56033 90187803
Balance disorder 308.90 57.05 28 384583 97052 90146784
Epistaxis 305.19 57.05 13 384598 85112 90158724
Atrial fibrillation 302.59 57.05 95 384516 133516 90110320
Injection site erythema 298.91 57.05 34 384577 98468 90145368
Lower limb fracture 298.66 57.05 916 383695 84097 90159739
Nasopharyngitis 289.94 57.05 2818 381793 404286 89839550
Hypoaesthesia 286.30 57.05 2296 382315 311914 89931922
Chills 279.59 57.05 105 384506 131876 90111960
Interstitial lung disease 272.82 57.05 12 384599 76393 90167443
Sciatica 272.38 57.05 998 383613 100384 90143452
Blepharospasm 271.90 57.05 675 383936 54770 90189066
X-ray abnormal 266.33 57.05 593 384018 44831 90199005
Weight increased 266.01 57.05 2827 381784 415100 89828736
Suicide attempt 265.46 57.05 13 384598 75386 90168450
Peripheral swelling 262.74 57.05 2794 381817 410312 89833524
Cognitive disorder 261.48 57.05 7 384604 69400 90174436
Road traffic accident 260.70 57.05 1025 383586 106601 90137235
Wrong technique in product usage process 256.35 57.05 11 384600 71560 90172276
Chronic obstructive pulmonary disease 255.92 57.05 14 384597 73815 90170021
Adverse event 253.36 57.05 1079 383532 116339 90127497
Hallucination 250.96 57.05 6 384605 65953 90177883
Suicidal ideation 247.00 57.05 17 384594 73838 90169998
Myocardial infarction 246.01 57.05 72 384539 105900 90137936
Alanine aminotransferase increased 245.92 57.05 97 384514 118241 90125595
Deep vein thrombosis 244.79 57.05 46 384565 91574 90152262
Inflammation 244.69 57.05 1443 383168 177149 90066687
Hypoglycaemia 242.88 57.05 13 384598 69835 90174001
Aspartate aminotransferase increased 242.54 57.05 68 384543 102869 90140967
Colitis 240.17 57.05 14 384597 69928 90173908
Swelling face 239.65 57.05 31 384580 81321 90162515
Blood pressure increased 238.92 57.05 291 384320 196926 90046910
Lupus vulgaris 238.52 57.05 565 384046 44494 90199342
Dry skin 235.77 57.05 44 384567 88029 90155807
Oxygen saturation decreased 235.33 57.05 81 384530 107402 90136434
Coma 233.64 57.05 20 384591 72612 90171224
Prescribed overdose 233.40 57.05 926 383685 96699 90147137
Overdose 232.87 57.05 196 384415 157513 90086323
Sinusitis 232.04 57.05 2350 382261 340738 89903098
Influenza 231.50 57.05 153 384458 139111 90104725
Wheezing 231.25 57.05 1766 382845 236314 90007522
Dyspnoea 230.53 57.05 2510 382101 878445 89365391
Dry mouth 229.91 57.05 1452 383159 182607 90061229
Thrombosis 228.08 57.05 23 384588 73228 90170608
Lung disorder 227.67 57.05 1245 383366 148638 90095198
Night sweats 222.77 57.05 1109 383502 127657 90116179
Influenza like illness 220.71 57.05 38 384573 80573 90163263
Blood glucose increased 220.57 57.05 65 384546 95181 90148655
Pleural effusion 219.58 57.05 100 384511 111891 90131945
Foot deformity 219.14 57.05 653 383958 58998 90184838
Hypokalaemia 215.31 57.05 146 384465 130970 90112866
Blood pressure decreased 214.79 57.05 31 384580 74864 90168972
Prescribed underdose 208.69 57.05 747 383864 74272 90169564
Injection site swelling 208.49 57.05 11 384600 59828 90184008
Onychomadesis 206.86 57.05 542 384069 45456 90198380
Retinitis 206.57 57.05 485 384126 37973 90205863
Mucosal inflammation 205.90 57.05 9 384602 57616 90186220
C-reactive protein 205.09 57.05 428 384183 30939 90212897
Skin exfoliation 204.65 57.05 24 384587 67889 90175947
Dysarthria 203.37 57.05 6 384605 54476 90189360
Cellulitis 203.15 57.05 67 384544 91270 90152566
Abortion spontaneous 201.61 57.05 6 384605 54050 90189786
Anti-cyclic citrullinated peptide antibody 201.35 57.05 391 384220 26830 90217006
Liver disorder 201.04 57.05 1032 383579 120237 90123599
Heart rate increased 197.36 57.05 117 384494 112785 90131051
Rash erythematous 196.20 57.05 23 384588 65081 90178755
Pneumonia 193.78 57.05 1753 382858 636306 89607530
Chronic kidney disease 193.16 57.05 4 384607 50187 90193649
Osteoarthritis 191.21 57.05 1454 383157 194276 90049560
Agitation 189.59 57.05 29 384582 67069 90176767
Vomiting 187.72 57.05 2293 382318 786000 89457836
Dyspnoea exertional 187.43 57.05 39 384572 72249 90171587
Loss of consciousness 185.02 57.05 193 384418 140045 90103791
Blood potassium decreased 182.90 57.05 4 384607 47723 90196113
Hyperglycaemia 181.99 57.05 8 384603 50962 90192874
International normalised ratio increased 181.19 57.05 4 384607 47312 90196524
Drug ineffective for unapproved indication 181.18 57.05 32 384579 66612 90177224
Cardiac disorder 179.32 57.05 17 384594 56855 90186981
Intentional product misuse 178.82 57.05 78 384533 89526 90154310
Disturbance in attention 176.53 57.05 5 384606 47104 90196732
Taste disorder 176.47 57.05 619 383992 60927 90182909
Angioedema 174.53 57.05 32 384579 64844 90178992
Unevaluable event 173.99 57.05 16 384595 54832 90189004
Dysgeusia 173.16 57.05 13 384598 52547 90191289
Hepatic function abnormal 173.13 57.05 5 384606 46283 90197553
Epilepsy 172.35 57.05 749 383862 81457 90162379
Lethargy 168.02 57.05 32 384579 63107 90180729
Red blood cell count decreased 166.40 57.05 7 384604 46344 90197492
Bone erosion 165.83 57.05 549 384062 52472 90191364
Condition aggravated 163.26 57.05 3485 381126 592060 89651776
Arthralgia 159.77 57.05 4378 380233 774144 89469692
Staphylococcal infection 159.53 57.05 12 384599 48427 90195409
Rash maculo-papular 158.57 57.05 3 384608 40930 90202906
Nail disorder 158.21 57.05 581 384030 58486 90185350
Injection site pruritus 157.39 57.05 21 384590 53813 90190023
Haemorrhage 155.82 57.05 50 384561 69319 90174517
Gastritis 154.39 57.05 5 384606 41748 90202088
Tachycardia 154.30 57.05 270 384341 157403 90086433
Incorrect dose administered 153.91 57.05 71 384540 78859 90164977
Vertigo 150.42 57.05 54 384557 69757 90174079
Hot flush 150.35 57.05 34 384577 59454 90184382
Fatigue 149.87 57.05 6149 378462 1147874 89095962
Hepatic failure 149.67 57.05 4 384607 39724 90204112
Bone pain 149.67 57.05 39 384572 61944 90181892
Lymphadenopathy 148.89 57.05 12 384599 45763 90198073
Abdominal pain 148.36 57.05 1026 383585 394695 89849141
Oedema 147.97 57.05 1398 383213 198897 90044939
Skin ulcer 147.68 57.05 19 384592 50056 90193780
Anaphylactic reaction 147.00 57.05 95 384516 87429 90156407
Exostosis 146.84 57.05 528 384083 52606 90191230
Respiratory distress 146.43 57.05 4 384607 38942 90204894
Flatulence 146.04 57.05 7 384604 41360 90202476
Depressed mood 145.86 57.05 20 384591 50202 90193634
Oropharyngeal pain 145.86 57.05 164 384447 115023 90128813
Renal disorder 145.76 57.05 3 384608 37856 90205980
Arrhythmia 143.74 57.05 9 384602 42323 90201513
Myelosuppression 142.95 57.05 27 384584 53564 90190272
Dry eye 142.68 57.05 35 384576 57896 90185940
Pneumonitis 142.51 57.05 12 384599 44158 90199678
Weight decreased 142.42 57.05 985 383626 378925 89864911
Femur fracture 142.09 57.05 15 384596 46067 90197769
Diabetes mellitus 140.09 57.05 50 384561 64825 90179011
Pain in jaw 139.62 57.05 19 384592 47966 90195870
Haematochezia 139.50 57.05 63 384548 70850 90172986
Transient ischaemic attack 138.56 57.05 12 384599 43164 90200672
Neoplasm progression 138.41 57.05 14 384597 44472 90199364
Urinary retention 137.88 57.05 5 384606 37739 90206097
Breast cancer 137.34 57.05 30 384581 53731 90190105
Lupus-like syndrome 137.21 57.05 488 384123 48358 90195478
Headache 137.14 57.05 2710 381901 860036 89383800
Blood alkaline phosphatase increased 135.33 57.05 21 384590 48058 90195778
Cholelithiasis 134.74 57.05 29 384582 52477 90191359
Emotional distress 133.43 57.05 5 384606 36657 90207179
Onychomycosis 133.34 57.05 405 384206 36971 90206865
Surgery 132.45 57.05 17 384594 44870 90198966
Transaminases increased 132.25 57.05 6 384605 37186 90206650
Macular degeneration 132.21 57.05 7 384604 37963 90205873
Pericardial effusion 130.78 57.05 6 384605 36827 90207009
Urinary incontinence 130.57 57.05 7 384604 37559 90206277
Septic shock 129.95 57.05 100 384511 84060 90159776
Urticaria 129.15 57.05 1953 382658 310781 89933055
Cystitis 128.57 57.05 61 384550 66657 90177179
Illness 128.35 57.05 96 384515 81873 90161963
Laryngitis 127.43 57.05 489 384122 50264 90193572
No adverse event 126.70 57.05 65 384546 67917 90175919
Haematuria 126.35 57.05 5 384606 34932 90208904
Irritability 126.00 57.05 6 384605 35656 90208180
Swollen tongue 125.06 57.05 22 384589 45934 90197902
Joint dislocation 124.03 57.05 444 384167 44138 90199698
Hepatic cirrhosis 123.29 57.05 564 384047 62689 90181147
Skin discolouration 123.28 57.05 20 384591 44295 90199541
Haemoptysis 123.17 57.05 4 384607 33316 90210520
Hypothyroidism 121.64 57.05 37 384574 53090 90190746
Hypophagia 120.96 57.05 8 384603 35929 90207907
Burning sensation 120.76 57.05 59 384552 63393 90180443
Angina pectoris 120.09 57.05 13 384598 39147 90204689
Mental disorder 119.04 57.05 4 384607 32314 90211522
Nasal congestion 117.86 57.05 108 384503 83306 90160530
Walking aid user 117.66 57.05 375 384236 35131 90208705
Hypertension 116.50 57.05 2650 381961 454882 89788954
Leukopenia 114.27 57.05 156 384455 100554 90143282
Foetal exposure during pregnancy 113.88 57.05 22 384589 42953 90200883
Jaundice 113.21 57.05 6 384605 32511 90211325
Paraesthesia oral 112.92 57.05 5 384606 31654 90212182
Restlessness 111.76 57.05 11 384600 35709 90208127
Throat irritation 111.33 57.05 34 384577 48661 90195175
Device issue 111.17 57.05 3 384608 29534 90214302
Productive cough 111.01 57.05 98 384513 76965 90166871
Stevens-Johnson syndrome 110.51 57.05 3 384608 29373 90214463
Musculoskeletal pain 110.34 57.05 1162 383449 170089 90073747
Asthenia 110.21 57.05 1598 383013 532153 89711683
Seronegative arthritis 110.20 57.05 241 384370 17993 90225843
Dysuria 109.12 57.05 18 384593 39383 90204453
Fungal infection 108.58 57.05 24 384587 42637 90201199
Hepatotoxicity 108.50 57.05 30 384581 45812 90198024
Metastases to liver 108.15 57.05 3 384608 28804 90215032
Eosinophilia 107.01 57.05 3 384608 28530 90215306
Disease recurrence 107.00 57.05 16 384595 37637 90206199
Hypercalcaemia 105.94 57.05 11 384600 34229 90209607
Eczema 105.52 57.05 46 384565 52824 90191012
Drug tolerance decreased 105.24 57.05 338 384273 31792 90212044
Dysphonia 105.22 57.05 69 384542 63015 90180821
Cytokine release syndrome 104.70 57.05 3 384608 27970 90215866
Presyncope 104.39 57.05 8 384603 31797 90212039
Sleep apnoea syndrome 104.16 57.05 8 384603 31739 90212097
Rash pruritic 104.14 57.05 117 384494 82097 90161739
Rhinorrhoea 104.08 57.05 133 384478 88183 90155653
Migraine 103.68 57.05 1250 383361 189142 90054694
Skin lesion 103.64 57.05 17 384594 37348 90206488
Back injury 103.27 57.05 432 384179 46190 90197646
C-reactive protein increased 102.34 57.05 1199 383412 180190 90063646
Vaginal haemorrhage 102.26 57.05 8 384603 31263 90212573
Red blood cell sedimentation rate increased 101.43 57.05 649 383962 81946 90161890
Inappropriate schedule of product administration 101.37 57.05 313 384298 149620 90094216
Maternal exposure timing unspecified 101.15 57.05 265 384346 22218 90221618
Throat tightness 100.92 57.05 6 384605 29478 90214358
Pallor 100.66 57.05 13 384598 34152 90209684
Product prescribing error 100.61 57.05 7 384604 30138 90213698
Basal cell carcinoma 100.09 57.05 12 384599 33377 90210459
Finger deformity 99.64 57.05 337 384274 32560 90211276
Clostridium difficile colitis 99.46 57.05 3 384608 26703 90217133
Product label confusion 99.42 57.05 266 384345 22584 90221252
Aggression 99.30 57.05 3 384608 26665 90217171
Oral candidiasis 96.42 57.05 17 384594 35438 90208398
Pollakiuria 96.19 57.05 13 384598 32992 90210844
Oral herpes 95.83 57.05 14 384597 33510 90210326
Candida infection 95.57 57.05 15 384596 34042 90209794
Blindness 95.41 57.05 4 384607 26564 90217272
Breast cancer stage II 94.98 57.05 348 384263 34986 90208850
Injection site bruising 94.55 57.05 52 384559 52255 90191581
Intestinal obstruction 94.28 57.05 21 384590 37110 90206726
Respiratory tract infection 94.03 57.05 68 384543 59010 90184826
Haematoma 93.45 57.05 25 384586 39023 90204813
Delirium 93.43 57.05 760 383851 103599 90140237
Gamma-glutamyltransferase increased 93.32 57.05 23 384588 37929 90205907
Eye irritation 93.04 57.05 16 384595 33962 90209874
Viral infection 92.75 57.05 30 384581 41384 90202452
Diplopia 92.09 57.05 8 384603 28706 90215130
Product administration error 91.60 57.05 5 384606 26418 90217418
Osteomyelitis 91.41 57.05 7 384604 27839 90215997
Drug level increased 91.07 57.05 7 384604 27755 90216081
Ocular hyperaemia 90.20 57.05 17 384594 33781 90210055
Atelectasis 89.98 57.05 3 384608 24406 90219430
Pregnancy 89.87 57.05 509 384102 61538 90182298
Stress 89.43 57.05 129 384482 81266 90162570
Clostridium difficile infection 89.06 57.05 22 384589 36223 90207613
Injection site rash 89.00 57.05 3 384608 24170 90219666
Neoplasm malignant 88.40 57.05 18 384593 33862 90209974
Eye pruritus 88.09 57.05 10 384601 29017 90214819
Rash macular 88.07 57.05 12 384599 30268 90213568
Speech disorder 87.34 57.05 42 384569 45543 90198293
Eye pain 87.24 57.05 39 384572 44129 90199707
Pulmonary mass 87.10 57.05 10 384601 28762 90215074
Eye swelling 87.02 57.05 11 384600 29375 90214461
Adverse drug reaction 86.85 57.05 816 383795 115885 90127951
Procedural pain 86.47 57.05 18 384593 33342 90210494
Limb injury 85.92 57.05 15 384596 31493 90212343
Dizziness 84.01 57.05 1883 382728 587401 89656435
Obstructive airways disorder 83.53 57.05 7 384604 25862 90217974
Lacrimation increased 82.94 57.05 9 384602 27053 90216783
Injection site haemorrhage 82.89 57.05 11 384600 28307 90215529
Panic attack 82.80 57.05 8 384603 26357 90217479
Eating disorder 81.95 57.05 11 384600 28062 90215774
Upper respiratory tract infection 81.09 57.05 276 384335 128042 90115794
Therapeutic response unexpected 79.57 57.05 3 384608 21877 90221959
Withdrawal syndrome 78.90 57.05 4 384607 22520 90221316
Drug eruption 78.67 57.05 26 384585 35381 90208455
Dyspepsia 78.08 57.05 1228 383383 196932 90046904
Sneezing 77.66 57.05 16 384595 29853 90213983
Coeliac disease 77.65 57.05 385 384226 44225 90199611
Photophobia 77.06 57.05 3 384608 21266 90222570
Disability 76.95 57.05 360 384251 40385 90203451
Therapy partial responder 76.95 57.05 4 384607 22039 90221797
Bronchitis 76.36 57.05 361 384250 152566 90091270
Mouth ulceration 76.32 57.05 37 384574 39937 90203899
Ulcer haemorrhage 75.67 57.05 265 384346 26056 90217780
Skin haemorrhage 74.26 57.05 4 384607 21376 90222460
Drug resistance 73.81 57.05 19 384592 30430 90213406
Rash papular 73.31 57.05 3 384608 20352 90223484
Product storage error 72.84 57.05 3 384608 20238 90223598
Conjunctivitis 72.20 57.05 13 384598 26693 90217143
Osteopenia 72.18 57.05 7 384604 22995 90220841
Abdominal pain upper 71.97 57.05 1885 382726 330789 89913047
Mood swings 71.51 57.05 4 384607 20698 90223138
Off label use 71.41 57.05 3889 380722 1098363 89145473
Injection site mass 71.26 57.05 6 384605 22084 90221752
Gallbladder disorder 71.05 57.05 3 384608 19800 90224036
Hepatic steatosis 70.84 57.05 34 384577 36911 90206925
Skin burning sensation 70.27 57.05 3 384608 19608 90224228
Nervous system disorder 69.29 57.05 6 384605 21587 90222249
Blood glucose decreased 68.82 57.05 9 384602 23420 90220416
Bronchospasm 68.56 57.05 5 384606 20704 90223132
Urosepsis 67.86 57.05 6 384605 21226 90222610
Accidental overdose 67.85 57.05 18 384593 28255 90215581
Joint destruction 67.49 57.05 164 384447 13123 90230713
Peritonitis 67.47 57.05 4 384607 19701 90224135
Abdominal pain lower 67.33 57.05 22 384589 30155 90213681
Cataract 67.33 57.05 127 384484 71965 90171871
Memory impairment 67.29 57.05 1194 383417 196050 90047786
Infusion site reaction 66.69 57.05 205 384406 18834 90225002
Rheumatoid arthritis 66.49 57.05 1110 383501 361504 89882332
Intervertebral disc protrusion 65.87 57.05 17 384594 27179 90216657
Liver function test increased 65.48 57.05 598 384013 84257 90159579
Musculoskeletal chest pain 65.44 57.05 11 384600 23739 90220097
Infusion site pain 64.68 57.05 5 384606 19733 90224103
Cardiac murmur 64.48 57.05 3 384608 18191 90225645
Skin disorder 64.18 57.05 38 384573 36668 90207168
Gastric disorder 63.59 57.05 31 384580 33353 90210483
Subcutaneous drug absorption impaired 63.35 57.05 162 384449 13383 90230453
Female genital tract fistula 63.15 57.05 3 384608 17865 90225971
Treatment noncompliance 62.93 57.05 76 384535 51651 90192185
Diverticulitis 62.07 57.05 60 384551 45127 90198709
Drug tolerance 61.91 57.05 192 384419 17724 90226112
Upper limb fracture 61.70 57.05 9 384602 21569 90222267
Porphyria acute 61.53 57.05 192 384419 17783 90226053
Anticipatory anxiety 61.41 57.05 47 384564 1186 90242650
Eye injury 61.38 57.05 141 384470 10879 90232957
Rib fracture 61.26 57.05 18 384593 26417 90217419
Skin fissures 61.11 57.05 8 384603 20801 90223035
Neutrophil count increased 60.59 57.05 6 384605 19384 90224452
Motor dysfunction 59.96 57.05 6 384605 19224 90224612
Localised infection 59.74 57.05 34 384577 33528 90210308
Gastric ulcer 59.52 57.05 21 384590 27427 90216409
Herpes zoster 59.50 57.05 204 384407 94440 90149396
Fluid retention 59.45 57.05 184 384427 87907 90155929
Post procedural complication 59.22 57.05 6 384605 19036 90224800
Poor quality sleep 58.73 57.05 16 384595 24677 90219159
Drug-induced liver injury 58.68 57.05 614 383997 89704 90154132
Systemic lupus erythematosus rash 58.61 57.05 61 384550 2328 90241508
Amnesia 58.42 57.05 711 383900 107794 90136042
Bronchiectasis 57.98 57.05 12 384599 22318 90221518
Dermatitis 57.57 57.05 12 384599 22208 90221628

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Bone cyst 288.53 35.32 75 15285 1576 42604399
Onychoclasis 227.38 35.32 69 15291 2583 42603392
Bone erosion 215.95 35.32 75 15285 4328 42601647
Tooth loss 208.53 35.32 72 15288 4082 42601893
Synovitis 205.59 35.32 104 15256 15463 42590512
Anti-cyclic citrullinated peptide antibody positive 204.35 35.32 59 15301 1853 42604122
Joint ankylosis 202.87 35.32 57 15303 1620 42604355
Lymphoma 201.86 35.32 100 15260 14221 42591754
Drug ineffective 195.06 35.32 580 14780 629617 41976358
Drug intolerance 171.15 35.32 176 15184 80248 42525727
Arthritis 162.80 35.32 129 15231 41936 42564039
Osteolysis 156.54 35.32 56 15304 3524 42602451
Red blood cell sedimentation rate abnormal 152.76 35.32 56 15304 3780 42602195
Catarrh 151.86 35.32 63 15297 5923 42600052
Burns second degree 150.75 35.32 63 15297 6033 42599942
Parosmia 149.32 35.32 67 15293 7624 42598351
Death 148.07 35.32 5 15355 471180 42134795
Alanine aminotransferase abnormal 145.89 35.32 58 15302 4886 42601089
Steroid dependence 144.82 35.32 63 15297 6659 42599316
Joint swelling 143.11 35.32 148 15212 67874 42538101
Hypopnoea 135.20 35.32 63 15297 7819 42598156
Inappropriate schedule of product administration 134.38 35.32 169 15191 95733 42510242
Intentional product use issue 132.92 35.32 146 15214 71687 42534288
Gingival pain 130.71 35.32 63 15297 8431 42597544
Alopecia 128.99 35.32 97 15263 29179 42576796
Frequent bowel movements 126.87 35.32 85 15275 21322 42584653
Systemic lupus erythematosus 125.14 35.32 63 15297 9261 42596714
Rhinitis 123.93 35.32 68 15292 11909 42594066
Arthropathy 123.64 35.32 95 15265 29502 42576473
Pain 119.03 35.32 268 15092 244580 42361395
Alcohol poisoning 116.01 35.32 56 15304 7518 42598457
Musculoskeletal stiffness 114.88 35.32 122 15238 57643 42548332
C-reactive protein abnormal 113.91 35.32 59 15301 9202 42596773
Rheumatoid arthritis 112.84 35.32 105 15255 42335 42563640
Cardiac murmur 111.81 35.32 65 15295 12710 42593265
Arthralgia 111.48 35.32 235 15125 205003 42400972
Psoriatic arthropathy 106.16 35.32 81 15279 24886 42581089
Drug specific antibody present 101.06 35.32 42 15318 3964 42602011
Neoplasm malignant 99.38 35.32 75 15285 22668 42583307
Impaired work ability 99.19 35.32 59 15301 12032 42593943
Drug tolerance decreased 92.29 35.32 34 15326 2326 42603649
Abdominal discomfort 90.38 35.32 123 15237 75132 42530843
Migraine 89.91 35.32 74 15286 25340 42580635
Impaired quality of life 88.11 35.32 58 15302 14119 42591856
Eczema 88.02 35.32 83 15277 34003 42571972
Therapeutic product effect decreased 85.54 35.32 87 15273 39063 42566912
Bronchiectasis 84.49 35.32 62 15298 17957 42588018
Contraindicated product administered 84.04 35.32 71 15289 25201 42580774
Swollen tongue 83.98 35.32 66 15294 21165 42584810
Stress 83.68 35.32 91 15269 44121 42561854
Haematochezia 77.05 35.32 100 15260 58336 42547639
Drug interaction 73.84 35.32 6 15354 266993 42338982
Ankle deformity 73.67 35.32 17 15343 212 42605763
Nightmare 68.60 35.32 63 15297 24949 42581026
Body temperature decreased 68.48 35.32 50 15310 14363 42591612
Tinnitus 68.16 35.32 67 15293 28871 42577104
Treatment failure 67.19 35.32 97 15263 62527 42543448
Anaemia 65.88 35.32 11 15349 280267 42325708
Hepatic steatosis 64.70 35.32 57 15303 21391 42584584
Vertigo 63.77 35.32 70 15290 34277 42571698
Skin injury 60.97 35.32 26 15334 2615 42603360
Mobility decreased 60.48 35.32 69 15291 35237 42570738
Neutropenia 59.50 35.32 3 15357 199428 42406547
Accidental overdose 58.33 35.32 61 15299 28269 42577706
Tubulointerstitial nephritis 58.05 35.32 64 15296 31484 42574491
Drug-induced liver injury 55.98 35.32 69 15291 38204 42567771
Medication error 55.45 35.32 64 15296 33090 42572885
Drug use disorder 54.03 35.32 38 15322 10295 42595680
Toxicity to various agents 53.81 35.32 9 15351 229127 42376848
Dysgeusia 52.21 35.32 63 15297 34126 42571849
Hand deformity 52.13 35.32 26 15334 3742 42602233
Rectal haemorrhage 51.98 35.32 76 15284 49530 42556445
Wrist deformity 51.52 35.32 14 15346 350 42605625
Condition aggravated 49.28 35.32 205 15155 260549 42345426
Febrile neutropenia 49.08 35.32 5 15355 185698 42420277
Loss of personal independence in daily activities 48.86 35.32 74 15286 49742 42556233
Diabetes mellitus 47.63 35.32 81 15279 60006 42545969
Pain in extremity 46.23 35.32 139 15221 150465 42455510
Hepatic fibrosis 45.85 35.32 26 15334 4846 42601129
Heart rate decreased 45.77 35.32 61 15299 36471 42569504
Therapeutic response decreased 45.15 35.32 61 15299 36951 42569024
Palpitations 45.00 35.32 72 15288 50725 42555250
Sepsis 44.27 35.32 9 15351 199325 42406650
Hepatitis 42.82 35.32 51 15309 27249 42578726
Hypertension 41.94 35.32 144 15216 167060 42438915
Bladder transitional cell carcinoma 41.62 35.32 20 15340 2656 42603319
Allergy to animal 41.59 35.32 13 15347 537 42605438
Vomiting 41.09 35.32 27 15333 289696 42316279
Upper respiratory tract infection 40.44 35.32 62 15298 42111 42563864
Colitis ulcerative 39.58 35.32 48 15312 26127 42579848
Blood pressure systolic increased 38.62 35.32 49 15311 27919 42578056
Pneumonia 38.50 35.32 58 15302 422091 42183884
Gastrointestinal infection 38.07 35.32 26 15334 6717 42599258
Aortic bruit 37.59 35.32 10 15350 230 42605745
Transfusion-related circulatory overload 37.31 35.32 13 15347 756 42605219
Blood pressure fluctuation 36.92 35.32 47 15313 26861 42579114
Platelet count decreased 35.91 35.32 4 15356 138577 42467398
Thrombocytopenia 35.76 35.32 12 15348 190267 42415708

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Pemphigus 3466.72 53.73 3623 309687 210947 110065042
Systemic lupus erythematosus 3455.04 53.73 3919 309391 250419 110025570
Hand deformity 3235.67 53.73 3523 309787 214983 110061006
Glossodynia 3227.71 53.73 3545 309765 218459 110057530
Synovitis 2849.63 53.73 3689 309621 270403 110005586
Pericarditis 2782.05 53.73 3262 310048 215852 110060137
Anti-cyclic citrullinated peptide antibody positive 2694.44 53.73 2935 310375 179049 110096940
Wound 2590.22 53.73 3253 310057 231184 110044805
Duodenal ulcer perforation 2526.78 53.73 2806 310504 174894 110101095
Helicobacter infection 2415.67 53.73 2772 310538 179105 110096884
Arthropathy 2249.03 53.73 3376 309934 284146 109991843
Alopecia 2226.76 53.73 3825 309485 360928 109915061
Swelling 2092.46 53.73 3643 309667 347398 109928591
Abdominal discomfort 1929.88 53.73 3756 309554 390102 109885887
Folliculitis 1817.83 53.73 2306 311004 165347 110110642
Discomfort 1814.85 53.73 2616 310694 212091 110063898
Contraindicated product administered 1795.30 53.73 2812 310498 245455 110030534
Acute kidney injury 1783.22 53.73 3 313307 635427 109640562
Hepatic enzyme increased 1677.88 53.73 3147 310163 317745 109958244
Drug intolerance 1655.08 53.73 3592 309718 402920 109873069
Irritable bowel syndrome 1616.89 53.73 2154 311156 162061 110113928
Muscle injury 1601.50 53.73 1984 311326 138823 110137166
Rheumatic fever 1502.51 53.73 1794 311516 120785 110155204
Impaired healing 1485.65 53.73 2274 311036 194443 110081546
Joint swelling 1483.78 53.73 3624 309686 439221 109836768
Rheumatoid factor positive 1458.80 53.73 1831 311479 129809 110146180
Blister 1452.20 53.73 2435 310875 224941 110051048
Maternal exposure during pregnancy 1344.35 53.73 2510 310800 252373 110023616
Psoriatic arthropathy 1339.54 53.73 2169 311141 194592 110081397
Infusion related reaction 1334.97 53.73 3174 310136 377988 109898001
Type 2 diabetes mellitus 1334.18 53.73 2046 311264 175186 110100803
Drug interaction 1310.74 53.73 21 313289 500162 109775827
Fibromyalgia 1306.22 53.73 1987 311323 168922 110107067
Toxicity to various agents 1295.60 53.73 12 313298 480543 109795446
Hypersensitivity 1287.18 53.73 3244 310066 400754 109875235
Sleep disorder due to general medical condition, insomnia type 1286.08 53.73 1541 311769 104102 110171887
Therapeutic product effect decreased 1275.99 53.73 2396 310914 241920 110034069
Death 1168.74 53.73 274 313036 698595 109577394
Anaemia 1126.20 53.73 120 313190 546966 109729023
Ill-defined disorder 1084.84 53.73 1742 311568 155111 110120878
Stomatitis 1043.89 53.73 2340 310970 267902 110008087
Swollen joint count increased 1037.25 53.73 1232 312078 82429 110193560
Facet joint syndrome 992.33 53.73 1296 312014 95532 110180457
Blood cholesterol increased 991.53 53.73 1834 311476 182951 110093038
Hypotension 988.59 53.73 152 313158 523697 109752292
Treatment failure 943.09 53.73 2284 311026 274950 110001039
Lower respiratory tract infection 935.31 53.73 2102 311208 241004 110034985
Neutropenia 915.49 53.73 33 313277 374587 109901402
Liver injury 882.19 53.73 1552 311758 148861 110127128
Lip dry 867.24 53.73 1235 312075 98848 110177141
Sepsis 839.77 53.73 18 313292 327328 109948661
Febrile neutropenia 826.43 53.73 14 313296 316753 109959236
Mobility decreased 817.95 53.73 1966 311344 235456 110040533
Injury 808.68 53.73 1643 311667 175622 110100367
Joint range of motion decreased 791.92 53.73 1316 311994 120516 110155473
C-reactive protein abnormal 786.20 53.73 1358 311952 128337 110147652
Constipation 724.32 53.73 83 313227 357703 109918286
Gastrointestinal disorder 698.46 53.73 1874 311436 240078 110035911
Breast cancer stage III 689.33 53.73 979 312331 78138 110197851
Bursitis 677.24 53.73 1274 312036 128644 110147345
Disease progression 672.81 53.73 3 313307 244031 110031958
Dehydration 661.35 53.73 31 313279 279480 109996509
Musculoskeletal stiffness 631.05 53.73 1984 311326 277838 109998151
Intentional product use issue 625.92 53.73 1829 311481 246077 110029912
Peripheral venous disease 612.58 53.73 957 312353 83160 110192829
Deep vein thrombosis postoperative 611.00 53.73 796 312514 58495 110217494
Haemoglobin decreased 583.87 53.73 29 313281 248698 110027291
Grip strength decreased 582.24 53.73 911 312399 79263 110196726
Respiratory failure 581.62 53.73 5 313305 215327 110060662
Thrombocytopenia 566.25 53.73 145 313165 348740 109927249
Renal failure 563.80 53.73 17 313293 226557 110049432
Wound infection 557.11 53.73 989 312321 95476 110180513
Product use issue 545.77 53.73 2031 311279 309664 109966325
Obesity 527.82 53.73 1060 312250 112291 110163698
Autoimmune disorder 519.09 53.73 775 312535 64708 110211281
Fall 517.90 53.73 568 312742 602914 109673075
Inflammation 516.98 53.73 1456 311854 191782 110084207
Sinusitis 511.71 53.73 1924 311386 294764 109981225
Live birth 510.75 53.73 794 312516 68690 110207299
Seizure 503.01 53.73 31 313279 221154 110054835
Infection 500.82 53.73 2193 311117 360007 109915982
Nasopharyngitis 498.45 53.73 2325 310985 392036 109883953
Hip arthroplasty 495.52 53.73 697 312613 55116 110220873
Hypoaesthesia 493.29 53.73 1978 311332 312245 109963744
Cardiac failure 490.43 53.73 8 313302 187618 110088371
Gait inability 486.19 53.73 1145 312165 135231 110140758
Contusion 484.64 53.73 1609 311701 231752 110044237
Somnolence 483.83 53.73 123 313187 297326 109978663
Osteoarthritis 483.60 53.73 1371 311939 181252 110094737
Weight increased 482.78 53.73 2408 310902 417236 109858753
Night sweats 473.39 53.73 1121 312189 132862 110143127
Renal impairment 469.34 53.73 14 313296 188431 110087558
Pain 467.80 53.73 4436 308874 950519 109325470
Sleep disorder 464.72 53.73 1427 311883 197217 110078772
Product dose omission issue 463.79 53.73 166 313144 321616 109954373
Sciatica 461.53 53.73 890 312420 91509 110184480
Blood creatinine increased 461.37 53.73 12 313298 182877 110093112
Peripheral swelling 455.95 53.73 2306 311004 401728 109874261
General physical health deterioration 455.43 53.73 2392 310918 422903 109853086
Dry mouth 454.44 53.73 1422 311888 198526 110077463
Lower limb fracture 451.21 53.73 785 312525 74563 110201426
Cough 448.53 53.73 389 312921 461252 109814737
Hypercholesterolaemia 441.57 53.73 865 312445 89972 110186017
Urinary tract infection 441.03 53.73 186 313124 326096 109949893
Knee arthroplasty 437.23 53.73 713 312597 64235 110211754
Blepharospasm 435.93 53.73 650 312660 54201 110221788
Platelet count decreased 427.11 53.73 70 313240 230373 110045616
Malignant neoplasm progression 424.03 53.73 16 313294 174551 110101438
Bradycardia 422.93 53.73 3 313307 155514 110120475
Syncope 409.65 53.73 47 313263 202489 110073500
Tremor 401.44 53.73 50 313260 202182 110073807
Gastrointestinal haemorrhage 399.21 53.73 16 313294 165502 110110487
Arthralgia 396.49 53.73 3652 309658 775980 109500009
Cardiac failure congestive 396.48 53.73 6 313304 150994 110124995
Road traffic accident 388.50 53.73 907 312403 106491 110169498
Pulmonary embolism 378.27 53.73 74 313236 214400 110061589
Nausea 378.01 53.73 2012 311298 1233678 109042311
Atrial fibrillation 377.18 53.73 93 313217 229549 110046440
Hyperhidrosis 374.98 53.73 45 313265 187253 110088736
Dislocation of vertebra 374.81 53.73 537 312773 43184 110232805
Adjustment disorder with depressed mood 371.82 53.73 536 312774 43347 110232642
Neuropathy peripheral 356.62 53.73 44 313266 179233 110096756
Onychomadesis 355.54 53.73 536 312774 45127 110230862
White blood cell count decreased 346.74 53.73 109 313201 229281 110046708
Interstitial lung disease 344.60 53.73 11 313299 139323 110136666
Foot deformity 343.77 53.73 545 312765 47935 110228054
Lung disorder 343.46 53.73 1207 312103 178840 110097149
Wheezing 342.36 53.73 1532 311778 253698 110022291
Adverse event 341.42 53.73 870 312440 107939 110168050
X-ray abnormal 339.78 53.73 477 312833 37640 110238349
Erythema 331.54 53.73 208 313102 291239 109984750
Nail disorder 329.29 53.73 590 312720 57345 110218644
Dysphagia 327.88 53.73 29 313281 153571 110122418
Myocardial infarction 320.91 53.73 75 313235 192008 110083981
C-reactive protein 316.77 53.73 410 312900 29921 110246068
Bone erosion 316.07 53.73 512 312798 45859 110230130
Musculoskeletal pain 310.35 53.73 1181 312129 181842 110094147
Back pain 309.34 53.73 357 312953 370639 109905350
Liver disorder 295.28 53.73 981 312329 141262 110134727
Cerebrovascular accident 294.61 53.73 75 313235 181209 110094780
Prescribed overdose 294.44 53.73 719 312591 86862 110189127
Retinitis 293.30 53.73 408 312902 31919 110244070
Electrocardiogram QT prolonged 287.46 53.73 4 313306 108956 110167033
Taste disorder 281.31 53.73 592 312718 64795 110211194
Myalgia 279.83 53.73 140 313170 222241 110053748
Lupus vulgaris 275.63 53.73 406 312904 33477 110242512
Coma 272.55 53.73 15 313295 117854 110158135
Hypoglycaemia 270.90 53.73 14 313296 116090 110159899
Confusional state 270.08 53.73 2258 311052 466422 109809567
Pneumonia 269.97 53.73 1423 311887 875291 109400698
COVID-19 267.69 53.73 183 313127 244877 110031112
Rash 258.84 53.73 3501 309809 817463 109458526
Hallucination 258.28 53.73 6 313304 101426 110174563
Pleural effusion 257.07 53.73 91 313219 177618 110098371
Pulmonary oedema 256.13 53.73 6 313304 100653 110175336
Chest discomfort 251.52 53.73 89 313221 173759 110102230
Epistaxis 249.72 53.73 36 313274 130336 110145653
Lactic acidosis 246.63 53.73 3 313307 92808 110183181
Hypokalaemia 246.41 53.73 104 313206 182344 110093645
Aspartate aminotransferase increased 243.44 53.73 75 313235 159861 110116128
Epilepsy 242.70 53.73 729 312581 99480 110176509
Urticaria 242.22 53.73 1640 311670 317217 109958772
Migraine 240.40 53.73 1044 312266 170608 110105381
Flushing 240.10 53.73 14 313296 104722 110171267
Suicide attempt 239.56 53.73 13 313297 103381 110172608
Vision blurred 239.43 53.73 39 313271 128983 110147006
Onychomycosis 237.91 53.73 407 312903 38124 110237865
Pregnancy 236.92 53.73 477 312833 50590 110225399
Chills 236.75 53.73 122 313188 190458 110085531
Exostosis 234.73 53.73 447 312863 45509 110230480
Septic shock 234.21 53.73 77 313233 157451 110118538
Anti-cyclic citrullinated peptide antibody 232.54 53.73 285 313025 19679 110256310
Mucosal inflammation 229.44 53.73 10 313300 96131 110179858
Chronic obstructive pulmonary disease 229.24 53.73 22 313288 109136 110166853
Hepatic function abnormal 228.46 53.73 5 313305 89290 110186699
Exposure during pregnancy 226.64 53.73 1008 312302 166416 110109573
Pulmonary fibrosis 225.48 53.73 719 312591 101323 110174666
International normalised ratio increased 225.45 53.73 4 313306 86768 110189221
Colitis 224.79 53.73 17 313293 102306 110173683
Dyspnoea 224.18 53.73 2032 311278 1104840 109171149
Feeling abnormal 222.52 53.73 117 313193 180594 110095395
Diarrhoea 220.02 53.73 2117 311193 1137388 109138601
Thrombosis 217.72 53.73 26 313284 108636 110167353
Agitation 217.03 53.73 31 313279 113020 110162969
Drug reaction with eosinophilia and systemic symptoms 216.62 53.73 3 313307 82092 110193897
Alanine aminotransferase increased 214.71 53.73 127 313183 183646 110092343
Back injury 213.08 53.73 437 312873 46962 110229027
Overdose 212.61 53.73 209 313101 233585 110042404
Haematuria 210.99 53.73 5 313305 83000 110192989
Lupus-like syndrome 209.86 53.73 398 312912 40394 110235595
Cognitive disorder 205.91 53.73 10 313300 87501 110188488
Balance disorder 203.83 53.73 41 313269 116519 110159470
Suicidal ideation 202.47 53.73 17 313293 93920 110182069
Mental status changes 195.78 53.73 4 313306 76118 110199871
Finger deformity 195.75 53.73 343 312967 32749 110243240
Injection site pain 195.42 53.73 132 313178 177790 110098199
Blood bilirubin increased 195.37 53.73 4 313306 75968 110200021
Rash maculo-papular 194.60 53.73 3 313307 74219 110201770
Tachycardia 193.26 53.73 214 313096 226431 110049558
Chronic kidney disease 192.38 53.73 5 313305 76286 110199703
Intentional product misuse 192.30 53.73 68 313242 132836 110143153
Maternal exposure timing unspecified 187.32 53.73 263 313047 20750 110255239
Blood creatine phosphokinase increased 187.31 53.73 4 313306 73073 110202916
Red blood cell sedimentation rate increased 186.17 53.73 566 312744 77736 110198253
Loss of consciousness 186.09 53.73 169 313141 196137 110079852
Laryngitis 185.92 53.73 387 312923 42024 110233965
Wrong technique in product usage process 185.02 53.73 17 313293 87331 110188658
Drug ineffective for unapproved indication 184.42 53.73 34 313276 102804 110173185
Oxygen saturation decreased 182.65 53.73 109 313201 156873 110119116
Acute respiratory failure 182.37 53.73 7 313303 75253 110200736
Abdominal pain upper 182.14 53.73 1646 311664 347465 109928524
Haemorrhage 181.48 53.73 40 313270 106652 110169337
Adverse drug reaction 180.35 53.73 683 312627 104876 110171113
C-reactive protein increased 180.06 53.73 1145 312165 216774 110059215
Melaena 179.33 53.73 3 313307 68754 110207235
Hyperglycaemia 179.07 53.73 17 313293 85073 110190916
Myelosuppression 178.47 53.73 27 313283 94313 110181676
Oedema 177.67 53.73 1110 312200 208866 110067123
Product label confusion 177.66 53.73 267 313043 22410 110253579
Cytokine release syndrome 175.82 53.73 5 313305 70301 110205688
Respiratory distress 175.64 53.73 4 313306 68870 110207119
Disorientation 173.23 53.73 6 313304 70665 110205324
Coeliac disease 173.10 53.73 380 312930 42807 110233182
Prescribed underdose 172.05 53.73 489 312821 64685 110211304
Angioedema 171.49 53.73 35 313275 98465 110177524
Hepatic failure 171.49 53.73 5 313305 68734 110207255
Dysarthria 171.35 53.73 19 313291 84102 110191887
Blood glucose increased 170.30 53.73 81 313229 132415 110143574
Haemoptysis 168.38 53.73 8 313302 71346 110204643
Urinary retention 167.10 53.73 7 313303 69676 110206313
Injection site erythema 167.03 53.73 32 313278 94144 110181845
Cellulitis 166.69 53.73 74 313236 125942 110150047
Lethargy 163.44 53.73 33 313277 93543 110182446
Pneumonitis 161.82 53.73 15 313295 76516 110199473
Dry skin 161.10 53.73 52 313258 107601 110168388
Orthostatic hypotension 161.08 53.73 6 313304 66243 110209746
Joint dislocation 160.55 53.73 321 312989 33869 110242120
Leukopenia 158.61 53.73 114 313196 148677 110127312
Blood pressure decreased 157.97 53.73 64 313246 115027 110160962
Arrhythmia 154.42 53.73 11 313299 69564 110206425
Hepatic cirrhosis 154.41 53.73 482 312828 67144 110208845
Aggression 152.72 53.73 3 313307 59207 110216782
Haematemesis 152.44 53.73 3 313307 59105 110216884
Memory impairment 150.63 53.73 1015 312295 195929 110080060
Red blood cell count decreased 150.52 53.73 9 313301 65914 110210075
Swelling face 146.52 53.73 40 313270 92281 110183708
Product quality issue 146.24 53.73 517 312793 76782 110199207
Disturbance in attention 146.13 53.73 7 313303 61988 110214001
Deep vein thrombosis 145.45 53.73 110 313200 139777 110136212
Jaundice 145.30 53.73 5 313305 59231 110216758
Palpitations 145.10 53.73 142 313168 159070 110116919
Rash erythematous 144.72 53.73 28 313282 81804 110194185
Staphylococcal infection 144.50 53.73 15 313295 69929 110206060
Eosinophilia 141.72 53.73 5 313305 57931 110218058
Pericardial effusion 139.75 53.73 5 313305 57212 110218777
Transient ischaemic attack 139.49 53.73 11 313299 63971 110212018
Hypertension 137.52 53.73 2118 311192 507966 109768023
Gastritis 137.39 53.73 3 313307 53696 110222293
Skin exfoliation 137.20 53.73 39 313271 87612 110188377
Neoplasm progression 135.67 53.73 13 313297 64582 110211407
Seronegative arthritis 134.28 53.73 176 313134 13001 110262988
Blood alkaline phosphatase increased 130.35 53.73 22 313288 70913 110205076
Shock 129.79 53.73 5 313305 53583 110222406
Influenza 129.00 53.73 174 313136 168927 110107062
Condition aggravated 128.82 53.73 2853 310457 731983 109544006
Blood potassium decreased 127.90 53.73 6 313304 54108 110221881
Dyspnoea exertional 127.15 53.73 68 313242 103992 110171997
Angina pectoris 127.05 53.73 14 313296 62281 110213708
Lymphadenopathy 126.09 53.73 16 313294 63819 110212170
Unevaluable event 124.18 53.73 12 313298 59215 110216774
Renal disorder 121.98 53.73 4 313306 49475 110226514
Lip swelling 121.79 53.73 5 313305 50662 110225327
Cardiac disorder 121.15 53.73 33 313277 76247 110199742
Hypothyroidism 120.65 53.73 29 313281 72870 110203119
Dyskinesia 120.64 53.73 6 313304 51440 110224549
Drug hypersensitivity 119.48 53.73 1878 311432 452212 109823777
Drug tolerance decreased 119.18 53.73 250 313060 27290 110248699
Restlessness 119.01 53.73 11 313299 56248 110219741
Influenza like illness 118.37 53.73 51 313259 88361 110187628
Blood pressure increased 118.16 53.73 358 312952 258015 110017974
Multiple sclerosis relapse 117.37 53.73 6 313304 50234 110225755
Heart rate increased 116.97 53.73 141 313169 143693 110132296
Off label use 114.82 53.73 3307 310003 1496878 108779111
Product prescribing error 114.25 53.73 8 313302 51323 110224666
Porphyria acute 114.12 53.73 197 313113 18583 110257406
Anaphylactic reaction 112.41 53.73 95 313215 114205 110161784
Hepatotoxicity 111.46 53.73 22 313288 63378 110212611
Walking aid user 111.29 53.73 230 313080 24845 110251144
Vomiting 111.24 53.73 1863 311447 908812 109367177
Breast cancer stage II 110.98 53.73 242 313068 27133 110248856
Irritability 110.77 53.73 6 313304 47803 110228186
Accidental exposure to product 110.71 53.73 8 313302 50000 110225989
Clostridium difficile colitis 109.89 53.73 3 313307 43775 110232214
Injection site swelling 109.56 53.73 21 313289 61769 110214220
Infusion site reaction 109.44 53.73 187 313123 17495 110258494
Skin ulcer 107.95 53.73 24 313286 63621 110212368
Disease recurrence 107.06 53.73 21 313289 60763 110215226
Hypophagia 106.89 53.73 12 313298 52614 110223375
Bacteraemia 106.05 53.73 3 313307 42387 110233602
Depressed mood 105.04 53.73 22 313288 60787 110215202
Liver function test increased 104.96 53.73 513 312797 88035 110187954
Arthritis 104.71 53.73 823 312487 166763 110109226
Gamma-glutamyltransferase increased 104.23 53.73 23 313287 61286 110214703
Head injury 104.23 53.73 4 313306 43013 110232976
Emotional distress 102.76 53.73 6 313304 44841 110231148
Pallor 102.69 53.73 18 313292 56449 110219540
Dysuria 101.58 53.73 23 313287 60208 110215781
Transaminases increased 101.47 53.73 27 313283 63363 110212626
Ear infection 100.68 53.73 398 312912 62334 110213655
Drug resistance 100.30 53.73 19 313291 56355 110219634
Dyspepsia 100.29 53.73 902 312408 190063 110085926
Drug level increased 99.18 53.73 10 313300 47709 110228280
Fatigue 99.02 53.73 4298 309012 1211660 109064329
Circulatory collapse 97.76 53.73 6 313304 42987 110233002
Presyncope 97.18 53.73 12 313298 48875 110227114
Abnormal behaviour 96.80 53.73 3 313307 39036 110236953
Obstructive airways disorder 95.06 53.73 10 313300 46139 110229850
Adverse reaction 94.19 53.73 238 313072 29356 110246633
Paraesthesia 93.69 53.73 1196 312114 275325 110000664
Red blood cell sedimentation rate abnormal 92.98 53.73 211 313099 24298 110251691
Urinary incontinence 91.68 53.73 14 313296 48573 110227416
Diplopia 89.13 53.73 8 313302 41886 110234103
Hypercalcaemia 89.06 53.73 13 313297 46644 110229345
Product administration error 88.37 53.73 4 313306 37213 110238776
Haematoma 87.92 53.73 28 313282 58448 110217541
Electrolyte imbalance 87.85 53.73 4 313306 37024 110238965
Injection site pruritus 87.60 53.73 19 313291 51239 110224750
Abdominal pain 87.12 53.73 981 312329 512008 109763981
Prostate cancer 86.36 53.73 5 313305 37636 110238353
Blindness 86.03 53.73 4 313306 36355 110239634
Therapy partial responder 84.79 53.73 5 313305 37056 110238933
Candida infection 83.68 53.73 17 313293 47992 110227997
Basal cell carcinoma 83.27 53.73 14 313296 45256 110230733
Hip fracture 82.74 53.73 4 313306 35147 110240842
Cholelithiasis 82.68 53.73 38 313272 63384 110212605
Flatulence 81.99 53.73 23 313287 52126 110223863
Neutrophil count increased 81.39 53.73 4 313306 34648 110241341
Device issue 81.07 53.73 4 313306 34531 110241458
Mental disorder 80.95 53.73 8 313302 38783 110237206
Incorrect dose administered 80.71 53.73 105 313205 103536 110172453
Abortion spontaneous 80.38 53.73 4 313306 34278 110241711
Neuroleptic malignant syndrome 79.77 53.73 4 313306 34055 110241934
Sinus disorder 79.44 53.73 3 313307 32725 110243264
Intestinal obstruction 79.12 53.73 26 313284 53201 110222788
Femur fracture 79.08 53.73 15 313295 44454 110231535
Hyperlipidaemia 78.60 53.73 6 313304 35842 110240147
Anticipatory anxiety 77.86 53.73 47 313263 1209 110274780
Drug eruption 76.68 53.73 28 313282 53631 110222358
Dementia 76.55 53.73 3 313307 31670 110244319
Joint destruction 76.15 53.73 122 313188 10821 110265168
Peritonitis 75.83 53.73 4 313306 32603 110243386
Ankle deformity 75.38 53.73 38 313272 678 110275311
Drug-induced liver injury 75.18 53.73 590 312720 119477 110156512
Systemic lupus erythematosus rash 74.82 53.73 55 313255 1980 110274009
Ulcer haemorrhage 74.44 53.73 184 313126 22387 110253602
COVID-19 pneumonia 74.11 53.73 9 313301 37134 110238855
Amnesia 73.91 53.73 532 312778 104876 110171113
Osteomyelitis 72.71 53.73 9 313301 36591 110239398
Pain in jaw 72.63 53.73 27 313283 51150 110224839
Pollakiuria 72.31 53.73 18 313292 44177 110231812
Skin lesion 72.01 53.73 28 313282 51603 110224386
Sleep apnoea syndrome 71.17 53.73 14 313296 40433 110235556
Nervous system disorder 70.44 53.73 5 313305 31716 110244273
Fungal infection 70.12 53.73 28 313282 50778 110225211
Pulmonary mass 69.80 53.73 11 313299 37290 110238699
Poisoning 69.53 53.73 3 313307 29102 110246887
Withdrawal syndrome 69.52 53.73 5 313305 31375 110244614
No adverse event 69.43 53.73 64 313246 73775 110202214
Skin discolouration 69.40 53.73 26 313284 49020 110226969
Grip strength 69.29 53.73 106 313204 9035 110266954
Bone pain 69.27 53.73 50 313260 65083 110210906
Dry eye 68.83 53.73 36 313274 55757 110220232
Speech disorder 68.49 53.73 45 313265 61524 110214465
Oesophagitis 68.46 53.73 3 313307 28712 110247277
Productive cough 68.18 53.73 138 313172 114167 110161822
Oral candidiasis 68.07 53.73 21 313289 44739 110231250
Appendicitis 67.78 53.73 3 313307 28461 110247528
Chromaturia 67.05 53.73 4 313306 29356 110246633
Rash pruritic 66.89 53.73 109 313201 97960 110178029
Joint stiffness 66.84 53.73 371 312939 66872 110209117
Rash macular 66.81 53.73 14 313296 38672 110237317
Myocarditis 65.98 53.73 5 313305 30050 110245939
Gout 65.74 53.73 12 313298 36554 110239435
Diabetes mellitus 65.44 53.73 113 313197 99268 110176721
Injection site reaction 65.05 53.73 454 312856 88616 110187373
Insomnia 64.89 53.73 1406 311904 359184 109916805
Liver function test abnormal 64.55 53.73 60 313250 68890 110207099
Viral infection 64.51 53.73 35 313275 53104 110222885
Vasculitis 64.01 53.73 12 313298 35861 110240128
Bronchospasm 63.73 53.73 6 313304 30233 110245756
Hot flush 63.57 53.73 56 313254 65980 110210009
Cytopenia 63.40 53.73 6 313304 30110 110245879
Dysphonia 63.26 53.73 73 313237 75856 110200133
Weight decreased 63.20 53.73 939 312371 467118 109808871
Therapy non-responder 62.73 53.73 702 312608 156605 110119384
Spondylitis 62.53 53.73 114 313196 11224 110264765
Bacterial infection 62.51 53.73 26 313284 46010 110229979
Rash papular 62.42 53.73 4 313306 27635 110248354
Clostridium difficile infection 62.32 53.73 35 313275 52094 110223895
Respiratory tract infection 61.69 53.73 67 313243 71550 110204439
Metastases to liver 60.71 53.73 13 313297 35373 110240616
Paraesthesia oral 60.64 53.73 11 313299 33660 110242329
Deafness 59.92 53.73 4 313306 26705 110249284
Urosepsis 59.83 53.73 8 313302 30667 110245322
Fluid retention 59.60 53.73 110 313200 94197 110181792
Haematochezia 59.53 53.73 151 313159 115373 110160616
Oropharyngeal pain 59.29 53.73 191 313119 135085 110140904
Metastases to bone 59.28 53.73 9 313301 31363 110244626
Eye swelling 59.08 53.73 11 313299 33037 110242952
Drug tolerance 58.76 53.73 139 313171 16446 110259543
Bone cyst 58.26 53.73 61 313249 3542 110272447
Burning sensation 58.25 53.73 66 313244 69146 110206843
Lacrimation increased 58.21 53.73 9 313301 30941 110245048
Swollen joint count 58.04 53.73 95 313215 8579 110267410
Eye irritation 57.99 53.73 12 313298 33440 110242549
Arteriosclerosis 57.72 53.73 3 313307 24764 110251225
Subcutaneous drug absorption impaired 56.91 53.73 88 313222 7571 110268418
Underdose 56.87 53.73 341 312969 63213 110212776
Treatment noncompliance 56.77 53.73 74 313236 72916 110203073
Motor dysfunction 56.74 53.73 3 313307 24403 110251586
Limb injury 56.62 53.73 18 313292 37618 110238371
Surgery 56.57 53.73 23 313287 41260 110234729
Throat tightness 56.05 53.73 13 313297 33476 110242513
Arteriosclerosis coronary artery 55.65 53.73 4 313306 25114 110250875
Panic attack 55.38 53.73 8 313302 28932 110247057
Osteoporosis 54.96 53.73 429 312881 86723 110189266
Gastric ulcer 54.88 53.73 22 313288 39805 110236184
Medication error 54.43 53.73 496 312814 104870 110171119
Muscle spasms 54.40 53.73 1098 312212 277059 109998930
Restless legs syndrome 54.34 53.73 4 313306 24622 110251367

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC D07AC03 DERMATOLOGICALS
CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
CORTICOSTEROIDS, PLAIN
Corticosteroids, potent (group III)
ATC D07XC02 DERMATOLOGICALS
CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
CORTICOSTEROIDS, OTHER COMBINATIONS
Corticosteroids, potent, other combinations
FDA MoA N0000175450 Corticosteroid Hormone Receptor Agonists
FDA EPC N0000175576 Corticosteroid
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D005938 Glucocorticoids
MeSH PA D006728 Hormones
CHEBI has role CHEBI:35472 anti-inflammatory drug
CHEBI has role CHEBI:50748 antipsoriatic
CHEBI has role CHEBI:59683 antipruritic drug

Related Drugs by ATC class:

D07AC Corticosteroids, potent (group III) 20 drugs
amcinonidebeclometasone dipropionatebetamethasonebudesonidediflorasone diacetatediflucortolonedifluprednatefluclorolonefludroxycortidefluocinolone acetonidefluocinonidefluocortolone show all 20 →
D07XC Corticosteroids, potent, other combinations 4 drugs
betamethasonediflucortolonefluocortolonemometasone furoate

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Atopic dermatitis indication 24079001 DOID:3310
Contact dermatitis indication 40275004 DOID:2773
Seborrheic dermatitis indication 50563003 DOID:8741
Lichen simplex chronicus indication 53891004
Granuloma annulare indication 65508009 DOID:3777
Pruritus ani indication 90446007
Discoid lupus erythematosus indication 200938002
Plaque psoriasis indication 200965009
Scalp psoriasis indication 238608008
Pruritus of genital organs indication 267802000
Eruption of skin indication 271807003 DOID:0050486
Primary cutaneous T-cell lymphoma indication 400122007
Hypopituitarism contraindication 74728003 DOID:9406
Atrophoderma contraindication 399979006
Peripheral vascular disease contraindication 400047006




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 11.54 acidic
pKa2 12.99 acidic

Orange Book patent data (new drug applications)

Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRoutePatent numberPatent expiration datePatent use
0.25% TOPICORT SUN PHARMA CANADA N204141 April 11, 2013 RX SPRAY TOPICAL 8715624 May 26, 2026 TREATMENT OF PLAQUE PSORIASIS IN PATIENTS 18 YEARS OF AGE OR OLDER
0.25% TOPICORT SUN PHARMA CANADA N204141 April 11, 2013 RX SPRAY TOPICAL 8277780 Sept. 1, 2028 TREATMENT OF PLAQUE PSORIASIS IN PATIENTS 18 YEARS OF AGE OR OLDER

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Glucocorticoid receptor Nuclear hormone receptor AGONIST Ki 8.93 DRUG MATRIX CHEMBL
Annexin A1 Cytosolic other WOMBAT-PK
Progesterone receptor Transcription factor Ki 7.96 DRUG MATRIX

External reference:

IDSource
4018465 VUID
N0000146789 NUI
D03697 KEGG_DRUG
3255 RXNORM
4018465 VANDF
C0011707 UMLSCUI
CHEBI:691037 CHEBI
CHEMBL1766 ChEMBL_ID
DB00547 DRUGBANK_ID
CHEMBL16829 ChEMBL_ID
D003899 MESH_DESCRIPTOR_UI
5311067 PUBCHEM_CID
7067 IUPHAR_LIGAND_ID
2467 INN_ID
4E07GXB7AU UNII
1103 MMSL
4551 MMSL
002180 NDDF
387473009 SNOMEDCT_US
81457006 SNOMEDCT_US
4E07GXB7AU INXIGHT DRUGS

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 0472-0478 CREAM 2.50 mg TOPICAL ANDA 14 sections
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 0472-0479 OINTMENT 2.50 mg TOPICAL ANDA 14 sections
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 40032-024 OINTMENT 2.50 mg TOPICAL ANDA 11 sections
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 42254-015 CREAM 2.50 mg TOPICAL ANDA 23 sections
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 45802-495 CREAM 2.50 mg TOPICAL ANDA 22 sections
desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 45802-496 OINTMENT 2.50 mg TOPICAL ANDA 21 sections
desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 45802-807 SPRAY 2.50 mg TOPICAL ANDA 26 sections
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 50090-0597 CREAM 2.50 mg TOPICAL ANDA 22 sections
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 50090-3919 CREAM 2.50 mg TOPICAL ANDA 14 sections
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 50090-5571 CREAM 2.50 mg TOPICAL ANDA 21 sections
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 51672-1261 GEL 0.50 mg TOPICAL ANDA 22 sections
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 51672-1262 OINTMENT 2.50 mg TOPICAL ANDA 22 sections
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 51672-1270 CREAM 2.50 mg TOPICAL ANDA 22 sections
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 51672-1271 CREAM 0.50 mg TOPICAL ANDA 22 sections
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 51672-1352 OINTMENT 0.50 mg TOPICAL NDA 22 sections
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 51672-1396 SPRAY 2.50 mg TOPICAL NDA authorized generic 29 sections
Topicort HUMAN PRESCRIPTION DRUG LABEL 1 51672-5203 OINTMENT 2.50 mg TOPICAL ANDA 22 sections
Topicort HUMAN PRESCRIPTION DRUG LABEL 1 51672-5263 OINTMENT 0.50 mg TOPICAL NDA 22 sections
Topicort HUMAN PRESCRIPTION DRUG LABEL 1 51672-5281 SPRAY 2.50 mg TOPICAL NDA 29 sections
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 52565-030 OINTMENT 2.50 mg TOPICAL ANDA 22 sections
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 52565-045 OINTMENT 0.50 mg TOPICAL ANDA 22 sections
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 53002-9280 CREAM 2.50 mg TOPICAL ANDA 14 sections
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 54868-2829 GEL 0.50 mg TOPICAL ANDA 23 sections
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 54868-3041 CREAM 2.50 mg TOPICAL ANDA 23 sections
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 54868-5891 OINTMENT 2.50 mg TOPICAL ANDA 22 sections
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 63187-646 CREAM 2.50 mg TOPICAL ANDA 22 sections
desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 63629-8641 OINTMENT 2.50 mg TOPICAL ANDA 22 sections
desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 63629-8642 OINTMENT 2.50 mg TOPICAL ANDA 22 sections
desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 63629-8702 SPRAY 2.50 mg TOPICAL ANDA 26 sections
Desoximetasone HUMAN PRESCRIPTION DRUG LABEL 1 65179-500 OINTMENT 2.50 mg TOPICAL ANDA 20 sections