Stem definition | Drug id | CAS RN |
---|---|---|
corticosteroids, except prednisolone derivatives | 1217 | 1524-88-5 |
None
None
Date | Agency | Company | Orphan |
---|---|---|---|
March 19, 1963 | FDA | AQUA PHARMS |
None
None
None
None
Source | Code | Description |
---|---|---|
ATC | D07AC07 | DERMATOLOGICALS CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS CORTICOSTEROIDS, PLAIN Corticosteroids, potent (group III) |
ATC | D07CC03 | DERMATOLOGICALS CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS Corticosteroids, potent, combinations with antibiotics |
FDA MoA | N0000175450 | Corticosteroid Hormone Receptor Agonists |
FDA EPC | N0000175576 | Corticosteroid |
MeSH PA | D000893 | Anti-Inflammatory Agents |
MeSH PA | D005938 | Glucocorticoids |
MeSH PA | D006728 | Hormones |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Atopic dermatitis | indication | 24079001 | DOID:3310 |
Contact dermatitis | indication | 40275004 | DOID:2773 |
Seborrheic dermatitis | indication | 50563003 | DOID:8741 |
Lichen simplex chronicus | indication | 53891004 | |
Granuloma annulare | indication | 65508009 | DOID:3777 |
Pruritus ani | indication | 90446007 | |
Discoid lupus erythematosus | indication | 200938002 | |
Plaque psoriasis | indication | 200965009 | |
Scalp psoriasis | indication | 238608008 | |
Pruritus of genital organs | indication | 267802000 | |
Eruption of skin | indication | 271807003 | DOID:0050486 |
Primary cutaneous T-cell lymphoma | indication | 400122007 | |
Telangiectasia disorder | contraindication | 247479008 | |
Adrenal cortical hypofunction | contraindication | 386584007 | DOID:10493 |
Atrophoderma | contraindication | 399979006 | |
Peripheral vascular disease | contraindication | 400047006 |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 11.78 | acidic |
pKa2 | 13.87 | acidic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Glucocorticoid receptor | Nuclear hormone receptor | AGONIST | Ki | 8.70 | DRUG MATRIX | CHEMBL | |||
Progesterone receptor | Transcription factor | Ki | 7.66 | DRUG MATRIX |
ID | Source |
---|---|
4019050 | VUID |
N0000147319 | NUI |
D00328 | KEGG_DRUG |
4019050 | VANDF |
C0016374 | UMLSCUI |
CHEBI:5127 | CHEBI |
CHEMBL1201012 | ChEMBL_ID |
DB00846 | DRUGBANK_ID |
7606 | IUPHAR_LIGAND_ID |
15209 | PUBCHEM_CID |
4500 | RXNORM |
240649 | MMSL |
4751 | MMSL |
002192 | NDDF |
16522004 | SNOMEDCT_US |
71455005 | SNOMEDCT_US |
D005478 | MESH_DESCRIPTOR_UI |
1123 | INN_ID |
8EUL29XUQT | UNII |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Cordran | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0023-5870 | TAPE | 4 ug | TOPICAL | NDA | 19 sections |
Cordran | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16110-026 | OINTMENT | 0.50 mg | TOPICAL | NDA | 21 sections |
Cordran | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16110-026 | OINTMENT | 0.50 mg | TOPICAL | NDA | 21 sections |
Cordran | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16110-034 | CREAM | 0.25 mg | TOPICAL | NDA | 21 sections |
Cordran | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16110-034 | CREAM | 0.25 mg | TOPICAL | NDA | 21 sections |
Cordran | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16110-035 | CREAM | 0.50 mg | TOPICAL | NDA | 21 sections |
Cordran | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16110-035 | CREAM | 0.50 mg | TOPICAL | NDA | 21 sections |
Cordran | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16110-052 | LOTION | 0.50 mg | TOPICAL | NDA | 19 sections |
CORDRAN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16110-587 | TAPE | 4 ug | TOPICAL | NDA | 12 sections |
CORDRAN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16110-587 | TAPE | 4 ug | TOPICAL | NDA | 12 sections |
Flurandrenolide Cream | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24470-919 | CREAM | 0.50 mg | TOPICAL | ANDA | 11 sections |
Flurandrenolide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24470-921 | LOTION | 0.50 mg | TOPICAL | ANDA | 10 sections |
Flurandrenolide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24470-921 | LOTION | 0.50 mg | TOPICAL | ANDA | 10 sections |
Flurandrenolide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 45802-928 | LOTION | 0.50 mg | TOPICAL | ANDA | 19 sections |
Flurandrenolide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 45802-928 | LOTION | 0.50 mg | TOPICAL | ANDA | 19 sections |
Flurandrenolide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51672-5298 | LOTION | 0.50 mg | TOPICAL | NDA | 21 sections |
Flurandrenolide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51672-5301 | CREAM | 0.50 mg | TOPICAL | NDA | 21 sections |
flurandrenolide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51862-158 | OINTMENT | 0.50 mg | TOPICAL | ANDA | 21 sections |
Flurandrenolide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 52565-017 | OINTMENT | 0.50 mg | TOPICAL | ANDA | 18 sections |
Nolix | HUMAN PRESCRIPTION DRUG LABEL | 1 | 57893-310 | CREAM | 0.50 mg | TOPICAL | ANDA | 10 sections |
Nolix | HUMAN PRESCRIPTION DRUG LABEL | 1 | 57893-311 | LOTION | 0.50 mg | TOPICAL | ANDA | 9 sections |
Nolix | HUMAN PRESCRIPTION DRUG LABEL | 1 | 57893-311 | LOTION | 0.50 mg | TOPICAL | ANDA | 9 sections |
Flurandrenolide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 63629-8657 | LOTION | 0.50 mg | TOPICAL | ANDA | 19 sections |
Flurandrenolide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 63629-8657 | LOTION | 0.50 mg | TOPICAL | ANDA | 19 sections |
Flurandrenolide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 63629-8657 | LOTION | 0.50 mg | TOPICAL | ANDA | 19 sections |
Flurandrenolide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 72162-1439 | LOTION | 0.50 mg | TOPICAL | ANDA | 19 sections |