DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
About
Download
L1000
FAQ
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All
FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
amcinonide 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
steroids for topical use, acetal derivatives
150
51022-69-6
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
amcinonide
amciderm
amcinonid
cyclocort
Molecular weight: 502.58
Formula: C28H35FO7
CLOGP: 2.88
LIPINSKI: 1
HAC: 7
HDO: 1
TPSA: 99.13
ALOGS: -4.81
ROTB: 4
Status: OFP
Legend:
OFP - off patent
OFM - off market
ONP - on patent
Drug dosage:
None
ADMET properties:
None
Approvals:
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Date
Agency
Company
Orphan
Oct. 18, 1979
FDA
ASTELLAS
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FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
D07AC11
DERMATOLOGICALS
CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
CORTICOSTEROIDS, PLAIN
Corticosteroids, potent (group III)
CHEBI has role
CHEBI:35472
anti-inflammatory drugs
FDA EPC
N0000175576
Corticosteroid
FDA MoA
N0000175450
Corticosteroid Hormone Receptor Agonists
MeSH PA
D005938
Glucocorticoids
MeSH PA
D006728
Hormones
Showing 1 to 6 of 6 entries
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
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Disease
Relation
SNOMED_ID
DOID
Atopic dermatitis
indication
24079001
DOID:3310
Contact dermatitis
indication
40275004
DOID:2773
Seborrheic dermatitis
indication
50563003
DOID:8741
Lichen simplex chronicus
indication
53891004
Granuloma annulare
indication
65508009
DOID:3777
Pruritus ani
indication
90446007
Discoid lupus erythematosus
indication
200938002
Plaque psoriasis
indication
200965009
Scalp psoriasis
indication
238608008
Pruritus of genital organs
indication
267802000
Showing 1 to 10 of 19 entries
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🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
11.08
acidic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Glucocorticoid receptor
Nuclear hormone receptor
P04150
GCR_HUMAN
AGONIST
CHEMBL
CHEMBL
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External reference:
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ID
Source
002202
NDDF
17652
RXNORM
222
MMSL
3755
INN_ID
4017920
VUID
4017920
VANDF
4163
MMSL
420859004
SNOMEDCT_US
423W026MA9
UNII
44051
MMSL
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Pharmaceutical products:
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Product
Category
Ingredients
NDC
Form
Quantity
Route
Marketing
Label
Amcinonide
HUMAN PRESCRIPTION DRUG LABEL
1
0168-0278
CREAM
1 mg
TOPICAL
ANDA
19 sections
Amcinonide
HUMAN PRESCRIPTION DRUG LABEL
1
0168-0278
CREAM
1 mg
TOPICAL
ANDA
19 sections
Amcinonide
HUMAN PRESCRIPTION DRUG LABEL
1
0168-0279
OINTMENT
1 mg
TOPICAL
ANDA
18 sections
amcinonide
HUMAN PRESCRIPTION DRUG LABEL
1
0168-0280
LOTION
1 mg
TOPICAL
ANDA
18 sections
Amcinonide
HUMAN PRESCRIPTION DRUG LABEL
1
51672-4054
CREAM
1 mg
TOPICAL
ANDA
20 sections
Amcinonide
HUMAN PRESCRIPTION DRUG LABEL
1
51672-4060
OINTMENT
1 mg
TOPICAL
ANDA
20 sections
Amcinonide
HUMAN PRESCRIPTION DRUG LABEL
1
73308-407
OINTMENT
1 mg
TOPICAL
ANDA
18 sections
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amcinonide