bibrocathol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
4352 6915-57-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • bibrocathol
  • bibrocathin
  • bismucatebrol
eye ointment; structure
  • Molecular weight: 649.67
  • Formula: C6HBiBr4O3
  • CLOGP: 3.19
  • LIPINSKI: 1
  • HAC: 3
  • HDO: 1
  • TPSA: 38.69
  • ALOGS: -3.24
  • ROTB: 0

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,ACVRL1,AKT1,AKT2,AKT3,ALK,AURKA,AURKC,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK1,CDK2,CDK4,CDK5,CDK9,DDR1,DYRK1B,DYRK3,EGFR,EIF2AK3,EPHB4,ERBB2,FLT3,FLT4,GRK2,GRK3,GSK3B,IGF1R,IKBKB,ITK,JAK1,JAK2,JAK3,KDR,KIT,MAP2K6,MAP3K14,MAP3K2,MAP3K21,MAP3K3,MAP3K7,MAP4K1,MAPK1,MAPK10,MAPK12,MAPK7,MAPK8,MAPK9,MAPKAPK2,MARK4,MELK,MET,MTOR,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CA,PIK3CB,PIK3CD,PIK3CG,PIM1,PIM2,PIM3,PLK1,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ULK1,ULK2,ZAP70 82
kinase-selectivity-class ACVR2A,ACVR2B,AURKA,AURKB,AURKC,AXL,BRAF,CAMK2B,CAMK2D,CDK16,CDK4,CDK9,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,GRK2,GSK3A,GSK3B,JAK2,MAP2K3,MAP2K6,MAP3K14,MAPK1,MAPK10,MAPK12,MAPK7,MAPK8,MARK4,MELK,MET,PDK4,PIK3CB,PIK3CG,PLK2,PLK3,PLK4,PRKDC,RIPK1,SGK1,SIK2,STK33,SYK,TEK,TGFBR1,TTK,TYRO3,UHMK1,ZAP70 50
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC S01AX05 SENSORY ORGANS
OPHTHALMOLOGICALS
ANTIINFECTIVES
Other antiinfectives
CHEBI has role CHEBI:66981 ophthalmology drug

Related Drugs by ATC class:

S01AX Other antiinfectives 13 drugs
cethexoniumchlorhexidinedibrompropamidinehexamidinelotilanernitrofurazonepicloxydinepolihexanidepovidone-iodinepropamidineresorcinolsodium borate show all 13 →

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07414 KEGG_DRUG
C0602838 UMLSCUI
CHEBI:135953 CHEBI
CHEMBL44875 ChEMBL_ID
DB13818 DRUGBANK_ID
C006748 MESH_SUPPLEMENTAL_RECORD_UI
79 INN_ID
0KJ20H1BLJ UNII
10100751 PUBCHEM_CID
006837 NDDF
1370972005 SNOMEDCT_US

Pharmaceutical products:

None