cethexonium 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
quaternary ammonium compounds 3080 1794-74-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • cethexonium bromide
  • biocidan
  • cethexonium
  • cethexonium chloride
  • Molecular weight: 368.67
  • Formula: C24H50NO
  • CLOGP: 4.97
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 1
  • TPSA: 20.23
  • ALOGS: -7.70
  • ROTB: 16

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,ACVRL1,AKT1,AKT2,AKT3,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GSK3B,IKBKB,ITK,JAK2,JAK3,MAP2K6,MAP3K21,MAP3K7,MAPK10,MAPK7,MAPK9,MAPKAPK2,MTOR,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CB,PIK3CG,PIM2,PLK1,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ZAP70 55
kinase-selectivity-class AKT2,AXL,CDK4,EIF2AK3,EPHB4,GRK2,INSR,MAP2K6,MAPK10,MTOR,PDK4,PLK1,PLK2,PLK3,PLK4,PTK2,STK33,TEK 18
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Ischaemic stroke 52.10 46.51 7 3 22159 90606278

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Ischaemic stroke 49.15 42.27 7 3 41256 110548033

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC S01AX26 SENSORY ORGANS
OPHTHALMOLOGICALS
ANTIINFECTIVES
Other antiinfectives
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000891 Anti-Infective Agents, Local
MeSH PA D013501 Surface-Active Agents

Related Drugs by ATC class:

S01AX Other antiinfectives 13 drugs
bibrocatholchlorhexidinedibrompropamidinehexamidinelotilanernitrofurazonepicloxydinepolihexanidepovidone-iodinepropamidineresorcinolsodium borate show all 13 →

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07737 KEGG_DRUG
6810-42-0 SECONDARY_CAS_RN
CHEMBL2110776 ChEMBL_ID
C013871 MESH_SUPPLEMENTAL_RECORD_UI
005395 NDDF
005396 NDDF
005397 NDDF
735133001 SNOMEDCT_US
735134007 SNOMEDCT_US
C0055145 UMLSCUI
CHEBI:135555 CHEBI
CHEMBL2105988 ChEMBL_ID
58703-78-9 SECONDARY_CAS_RN
110926 PUBCHEM_CID
1V984I1L1M UNII
4076 INN_ID

Pharmaceutical products:

None