All FDA-approved EMA-approved PMDA-approved
Target Card Uniprot Example: P23975

sodium borate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4795	1330-43-4

Description:

Molecule	Description
Synonyms: sodium borate borax sodium tetraborate	see also sodium borate Molecular weight: 201.21 Formula: B4Na2O7 CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: 107.95 ALOGS: ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Gastrointestinal toxicity	311.39	23.37	76	3796	7665	63477485
Pulmonary toxicity	286.52	23.37	74	3798	9381	63475769
Neoplasm malignant	210.11	23.37	76	3796	29785	63455365
Joint injury	207.08	23.37	75	3797	29497	63455653
Hepatotoxicity	194.17	23.37	76	3796	36965	63448185
C-reactive protein abnormal	161.68	23.37	71	3801	46025	63439125
Musculoskeletal pain	149.49	23.37	84	3788	92193	63392957
Joint stiffness	145.22	23.37	64	3808	41805	63443345
Therapy non-responder	141.97	23.37	76	3796	75825	63409325
Musculoskeletal stiffness	92.73	23.37	82	3790	184536	63300614
Pain in extremity	85.82	23.37	103	3769	331383	63153767
Treatment failure	72.40	23.37	74	3798	198969	63286181
Therapeutic product effect incomplete	69.68	23.37	59	3813	124997	63360153
Infection	67.17	23.37	76	3796	229097	63256053
Joint swelling	55.69	23.37	83	3789	327583	63157567
Arthropathy	51.07	23.37	67	3805	234725	63250425
Drug hypersensitivity	42.09	23.37	71	3801	310616	63174534
Condition aggravated	40.71	23.37	81	3791	402136	63083014
Arthralgia	36.80	23.37	96	3776	569614	62915536
Drug intolerance	34.65	23.37	65	3807	308596	63176554
Rheumatoid arthritis	29.14	23.37	54	3818	253765	63231385
Inflammation	25.23	23.37	28	3844	82245	63402905

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Periarthritis	37.30	25.24	8	895	1076	34954952

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Gastrointestinal toxicity	185.15	20.99	48	3673	8061	79732606
Pulmonary toxicity	163.04	20.99	48	3673	12866	79727801
Joint injury	124.85	20.99	49	3672	31286	79709381
Neoplasm malignant	124.14	20.99	49	3672	31761	79708906
Joint stiffness	105.84	20.99	47	3674	40783	79699884
Hepatotoxicity	98.55	20.99	48	3673	51304	79689363
Musculoskeletal pain	89.47	20.99	57	3664	102297	79638370
C-reactive protein abnormal	86.21	20.99	43	3678	48324	79692343
Therapy non-responder	69.88	20.99	47	3674	92258	79648409
Musculoskeletal stiffness	50.84	20.99	51	3670	174957	79565710
Pain in extremity	49.31	20.99	72	3649	364466	79376201
Treatment failure	44.65	20.99	47	3674	170439	79570228
Joint swelling	40.42	20.99	58	3663	288588	79452079
Therapeutic product effect incomplete	33.46	20.99	37	3684	141608	79599059
Infection	32.98	20.99	48	3673	241664	79499003
Rheumatoid arthritis	32.29	20.99	44	3677	208426	79532241
Arthropathy	29.91	20.99	39	3682	177072	79563595
Arthralgia	24.45	20.99	70	3651	571733	79168934
Drug hypersensitivity	22.98	20.99	46	3675	298870	79441797
Inflammation	21.28	20.99	24	3697	93729	79646938

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	S01AX07	SENSORY ORGANS OPHTHALMOLOGICALS ANTIINFECTIVES Other antiinfectives
CHEBI has role	CHEBI:35225	buffer compounds

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
91MBZ8H3QO	UNII
D03243	KEGG_DRUG
4024916	VUID
N0000147505	NUI
4019309	VANDF
4024916	VANDF
C0074727	UMLSCUI
CHEBI:38909	CHEBI
CHEMBL3833375	ChEMBL_ID
DB14505	DRUGBANK_ID
CHEMBL2097011	ChEMBL_ID
CHEMBL1076681	ChEMBL_ID
C010634	MESH_SUPPLEMENTAL_RECORD_UI
C018851	MESH_SUPPLEMENTAL_RECORD_UI
36680	RXNORM
5210	MMSL
5475	MMSL
NOCODE	MMSL
001980	NDDF
011732	NDDF
50306007	SNOMEDCT_US
1303-96-4	SECONDARY_CAS_RN
16211214	PUBCHEM_CID

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Calcemin Advance	HUMAN OTC DRUG LABEL	5	0280-0272	TABLET, FILM COATED	2.45 mg	ORAL	Export only	2 sections
MA YING LONG HEMORRHOIDAL	HUMAN OTC DRUG LABEL	7	69396-006	OINTMENT	0.20 g	TOPICAL	unapproved drug other	11 sections
Miel Rosada	HUMAN OTC DRUG LABEL	2	70242-127	SOLUTION	0.10 mg	TOPICAL	OTC monograph not final	8 sections
Borax	HUMAN OTC DRUG LABEL	1	79718-1023	LIQUID	30 [hp_C]	ORAL	unapproved homeopathic	7 sections
Borax	HUMAN OTC DRUG LABEL	1	79718-1164	LIQUID	200 [hp_C]	ORAL	unapproved homeopathic	8 sections