resorcinol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
3524 108-46-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • resorcinol
  • resorcin
  • benzene-1,3-diol
an antiseptic and disinfectant used for temporary relief of itching
  • Molecular weight: 110.11
  • Formula: C6H6O2
  • CLOGP: 0.81
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 2
  • TPSA: 40.46
  • ALOGS: -0.13
  • ROTB: 0

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC D10AX02 DERMATOLOGICALS
ANTI-ACNE PREPARATIONS
ANTI-ACNE PREPARATIONS FOR TOPICAL USE
Other anti-acne preparations for topical use
ATC S01AX06 SENSORY ORGANS
OPHTHALMOLOGICALS
ANTIINFECTIVES
Other antiinfectives
CHEBI has role CHEBI:91025 EPO inhibitor
CHEBI has role CHEBI:139492 sensitizers

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Acne vulgaris indication 88616000
Skin irritation indication 367466007
Acneiform eruption indication 402644006
Itching of skin indication 418363000
Minor Skin Wound Pain indication
Folliculitis contraindication 13600006 DOID:4409
Infection of skin AND/OR subcutaneous tissue contraindication 19824006
Methemoglobinemia contraindication 38959009 DOID:10783
Conduction disorder of the heart contraindication 44808001
Diabetes mellitus contraindication 73211009 DOID:9351
Decreased respiratory function contraindication 80954004
Kidney disease contraindication 90708001 DOID:557
Anemia due to enzyme deficiency contraindication 111577008
Deficiency of glucose-6-phosphate dehydrogenase contraindication 124134002 DOID:2862
Deficiency of cytochrome-b>5< reductase contraindication 124184009
Open wound contraindication 125643001
Seizure disorder contraindication 128613002
Condyloma acuminatum contraindication 240542006 DOID:11168
Eruption of skin contraindication 271807003 DOID:0050486
Peripheral vascular disease contraindication 400047006
Blister contraindication 417237009
Denuded skin contraindication 418242004
Inflammatory dermatosis contraindication 703938007




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.01 acidic
pKa2 11.02 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Carbonic anhydrase 2 Enzyme Ki 5.11 CHEMBL
Carbonic anhydrase 9 Enzyme Ki 4.16 CHEMBL
Carbonic anhydrase 12 Enzyme Ki 5.12 CHEMBL
Carbonic anhydrase 5A, mitochondrial Enzyme Ki 5.06 CHEMBL
Carbonic anhydrase 5B, mitochondrial Enzyme Ki 5.15 CHEMBL
Carbonic anhydrase 14 Enzyme Ki 4.97 CHEMBL
Carbonic anhydrase 13 Enzyme Ki 4.20 CHEMBL
Prostaglandin G/H synthase 1 Enzyme Kd 4.06 CHEMBL
Carbonic anhydrase Enzyme Ki 5.19 CHEMBL

External reference:

IDSource
YUL4LO94HK UNII
4019032 VUID
N0000147303 NUI
D00133 KEGG_DRUG
4019032 VANDF
C0073085 UMLSCUI
CHEBI:27810 CHEBI
RCO PDB_CHEM_ID
CHEMBL24147 ChEMBL_ID
5054 PUBCHEM_CID
DB11085 DRUGBANK_ID
C031389 MESH_SUPPLEMENTAL_RECORD_UI
35382 RXNORM
5052 MMSL
5418 MMSL
001950 NDDF
411296008 SNOMEDCT_US
78032005 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
good sense vagicaineanti itch HUMAN OTC DRUG LABEL 2 0113-0142 CREAM 3 g TOPICAL OTC monograph not final 13 sections
Adult Acnomel Tinted HUMAN OTC DRUG LABEL 2 0295-9116 CREAM 2 g TOPICAL OTC monograph final 12 sections
Anti-Itch Regular Strength HUMAN OTC DRUG LABEL 2 0363-0621 CREAM 2 g TOPICAL OTC monograph final 11 sections
Well at Walgreens Anti-Itch Maximum Strength HUMAN OTC DRUG LABEL 2 0363-0674 CREAM 3 g TOPICAL OTC monograph final 11 sections
Anti-Itch Medicated Maximum Strength HUMAN OTC DRUG LABEL 2 0363-2311 CREAM 30 mg TOPICAL OTC MONOGRAPH NOT FINAL 11 sections
Tinted Acne Treatment HUMAN OTC DRUG LABEL 2 0363-7783 CREAM 2 g TOPICAL OTC monograph final 7 sections
REZAMID HUMAN OTC DRUG LABEL 2 11086-022 LOTION 2 1 TOPICAL OTC monograph final 11 sections
VAGISIL Anti-Itch Medicated Creme Maximum Strength HUMAN OTC DRUG LABEL 2 11509-4402 CREAM 30 mg TOPICAL OTC MONOGRAPH NOT FINAL 11 sections
VAGISIL Anti-Itch Creme Regular Strength HUMAN OTC DRUG LABEL 2 11509-5103 CREAM 20 mg TOPICAL OTC MONOGRAPH NOT FINAL 10 sections
Up and up vagicaine HUMAN OTC DRUG LABEL 2 11673-142 CREAM 3 g TOPICAL OTC monograph not final 13 sections
BENZOCAINE and RESORCINOL HUMAN OTC DRUG LABEL 2 11822-2890 OINTMENT 20 mg TOPICAL OTC monograph not final 7 sections
Rite Aid Original Strength Vagicaine HUMAN OTC DRUG LABEL 2 11822-2891 CREAM 20 mg TOPICAL OTC monograph not final 7 sections
Vagicaine Medicated Maximum Strength HUMAN OTC DRUG LABEL 2 11822-5880 CREAM 30 mg TOPICAL OTC MONOGRAPH NOT FINAL 11 sections
Rite Aid Original Strength Vagicaine HUMAN OTC DRUG LABEL 2 11822-9974 CREAM 2 g TOPICAL OTC monograph not final 9 sections
signature care vagicaine HUMAN OTC DRUG LABEL 2 21130-142 CREAM 3 g TOPICAL OTC monograph not final 13 sections
Budpak Feminine Anti-Itch HUMAN OTC DRUG LABEL 2 27293-022 CREAM 0.02 g TOPICAL OTC monograph not final 10 sections
Vagicaine HUMAN OTC DRUG LABEL 2 29500-7820 CREAM 0.85 g TOPICAL OTC monograph not final 12 sections
AssuredFeminine Anti-itch HUMAN OTC DRUG LABEL 2 33992-2014 CREAM 2 g TOPICAL OTC monograph not final 10 sections
VagicaineMaximum Strength HUMAN OTC DRUG LABEL 2 41250-142 CREAM 3 g TOPICAL OTC monograph not final 13 sections
good neighbor pharmacy vagicaine HUMAN OTC DRUG LABEL 2 46122-576 CREAM 3 g TOPICAL OTC monograph not final 13 sections
Well at Walgreens Anti-ItchMaximum Strength HUMAN OTC DRUG LABEL 2 47046-181 CREAM 3 g TOPICAL OTC monograph final 11 sections
Leader Anti-Itch Maximum Strength HUMAN OTC DRUG LABEL 2 49781-092 CREAM 30 mg TOPICAL OTC monograph final 11 sections
Family Wellness HUMAN OTC DRUG LABEL 2 55621-016 CREAM 3 g TOPICAL OTC monograph not final 9 sections
OptimV Anti-ItchMaximum Strength HUMAN OTC DRUG LABEL 2 55758-300 CREAM 3 g TOPICAL OTC monograph not final 13 sections
CLARIFYING MASK HUMAN OTC DRUG LABEL 2 55878-102 PASTE 2 g TOPICAL OTC monograph final 10 sections
CLARIFYING MASK HUMAN OTC DRUG LABEL 2 55878-106 PASTE 2 g TOPICAL OTC monograph final 11 sections
DG HealthFeminine Anti-itch HUMAN OTC DRUG LABEL 2 55910-158 CREAM 3 g TOPICAL OTC monograph not final 11 sections
BENZOCAINE and RESORCINOL HUMAN OTC DRUG LABEL 2 55910-185 CREAM 20 mg TOPICAL OTC monograph not final 7 sections
REXALL FEMININE MAXIMUM STRENGTH ANTI-ITCH HUMAN OTC DRUG LABEL 2 55910-415 CREAM 3 g TOPICAL OTC monograph final 11 sections
Vagicaine Maximum Strength Anti-Itch Cream HUMAN OTC DRUG LABEL 2 59779-588 CREAM 0.84 g TOPICAL OTC monograph not final 12 sections