picloxydine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	3467	5636-92-0

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

picloxydine dihydrochloride
picloxydine hydrochloride
picloxydine HCl
vitabact
picloxydine

Molecular weight: 475.38
Formula: C20H24Cl2N10
CLOGP: 4.40
LIPINSKI: 1
HAC: 10
HDO: 8
TPSA: 150
ALOGS: -3.92
ROTB: 2

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	S01AX16	SENSORY ORGANS OPHTHALMOLOGICALS ANTIINFECTIVES Other antiinfectives

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	12.31	Basic
pKa2	11.71	Basic
pKa3	2.17	Basic
pKa4	1.56	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Acetylcholinesterase	Enzyme		ACES_ELEEL		Ki	4.66		CHEMBL
Cholinesterase	Enzyme		CHLE_HORSE		Ki	6.21		CHEMBL

External reference:

ID	Source
D07415	KEGG_DRUG
19803-62-4	SECONDARY_CAS_RN
C0071036	UMLSCUI
CHEBI:135768	CHEBI
CHEMBL2104722	ChEMBL_ID
DB13607	DRUGBANK_ID
C005253	MESH_SUPPLEMENTAL_RECORD_UI
1519	INN_ID
4YC2PY3AEU	UNII
5748610	PUBCHEM_CID
005716	NDDF
005717	NDDF
717152000	SNOMEDCT_US
735171009	SNOMEDCT_US

Pharmaceutical products:

None