oxaceprol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
2005 33996-33-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • oxaceprol
  • N-Acetyl-4-hydroxy-L-proline
  • N-Acetyl-4-hydroxyproline
  • N-Acetyl-L-hydroxyproline
  • N-Acetyl-trans-4-hydroxy-L-proline
  • N-Acetylhydroxyproline
Oxaceprol, is an atypical inhibitor of inflammation which helps in reduction of leukocyte adherence for joint diseases. This medicine is used for osteoarthritis or degenerative joint disorders and inflammation of connective tissues.
  • Molecular weight: 173.17
  • Formula: C7H11NO4
  • CLOGP: -1.91
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 2
  • TPSA: 77.84
  • ALOGS: 0.57
  • ROTB: 1

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC D11AX09 DERMATOLOGICALS
OTHER DERMATOLOGICAL PREPARATIONS
OTHER DERMATOLOGICAL PREPARATIONS
Other dermatologicals
ATC M01AX24 MUSCULO-SKELETAL SYSTEM
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Other antiinflammatory and antirheumatic agents, non-steroids
MeSH PA D018501 Antirheumatic Agents
MeSH PA D003879 Dermatologic Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Osteoarthritis indication 396275006




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.67 acidic
pKa2 13.57 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07215 KEGG_DRUG
C0064164 UMLSCUI
CHEMBL1407356 ChEMBL_ID
CHEMBL2105621 ChEMBL_ID
DB13363 DRUGBANK_ID
65784 PUBCHEM_CID
3891 INN_ID
C012393 MESH_SUPPLEMENTAL_RECORD_UI
Q0XV76B96L UNII
28068 RXNORM
006313 NDDF
713480005 SNOMEDCT_US

Pharmaceutical products:

None