Stem definition | Drug id | CAS RN |
---|---|---|
heparin derivatives including low molecular mass heparins | 1358 | 9005-49-6 |
Molecule | Description |
---|---|
Synonyms:
|
A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts.
|
Dose | Unit | Route |
---|---|---|
10 | TU | P |
None
Date | Agency | Company | Orphan |
---|---|---|---|
Feb. 9, 1939 | FDA | ORGANON USA INC |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Heparin-induced thrombocytopenia | 2299.17 | 11.38 | 563 | 44520 | 3402 | 50556639 |
Premature delivery | 303.46 | 11.38 | 214 | 44869 | 23449 | 50536592 |
Shock haemorrhagic | 229.74 | 11.38 | 123 | 44960 | 8221 | 50551820 |
Haemorrhage | 216.01 | 11.38 | 252 | 44831 | 53189 | 50506852 |
Hereditary angioedema | 210.64 | 11.38 | 101 | 44982 | 5341 | 50554700 |
Labelled drug-drug interaction medication error | 201.06 | 11.38 | 122 | 44961 | 10355 | 50549686 |
Maternal exposure during pregnancy | 189.76 | 11.38 | 431 | 44652 | 159347 | 50400694 |
Thrombocytopenia | 182.10 | 11.38 | 371 | 44712 | 127302 | 50432739 |
Vascular stent thrombosis | 182.08 | 11.38 | 56 | 45027 | 853 | 50559188 |
Exposure during pregnancy | 170.61 | 11.38 | 350 | 44733 | 120665 | 50439376 |
Rheumatoid arthritis | 161.56 | 11.38 | 4 | 45079 | 202546 | 50357495 |
Retroperitoneal haematoma | 149.76 | 11.38 | 64 | 45019 | 2579 | 50557462 |
Cerebral haemorrhage | 146.71 | 11.38 | 149 | 44934 | 26903 | 50533138 |
Pulmonary embolism | 146.68 | 11.38 | 297 | 44786 | 101407 | 50458634 |
Retroperitoneal haemorrhage | 145.18 | 11.38 | 62 | 45021 | 2494 | 50557547 |
Abdominal wall haematoma | 144.99 | 11.38 | 63 | 45020 | 2645 | 50557396 |
Haematoma | 142.20 | 11.38 | 155 | 44928 | 30355 | 50529686 |
Joint swelling | 133.39 | 11.38 | 28 | 45055 | 245258 | 50314783 |
Haemorrhage intracranial | 131.62 | 11.38 | 100 | 44983 | 12274 | 50547767 |
Drug intolerance | 119.14 | 11.38 | 25 | 45058 | 219079 | 50340962 |
Arthropathy | 115.95 | 11.38 | 6 | 45077 | 157900 | 50402141 |
Thrombosis in device | 115.67 | 11.38 | 54 | 45029 | 2687 | 50557354 |
Arthralgia | 114.13 | 11.38 | 134 | 44949 | 438568 | 50121473 |
Vascular pseudoaneurysm | 110.98 | 11.38 | 43 | 45040 | 1341 | 50558700 |
Acute kidney injury | 110.89 | 11.38 | 449 | 44634 | 227609 | 50332432 |
Extradural haematoma | 108.70 | 11.38 | 44 | 45039 | 1543 | 50558498 |
Alopecia | 99.45 | 11.38 | 47 | 45036 | 245000 | 50315041 |
Thrombosis | 97.59 | 11.38 | 177 | 44906 | 55656 | 50504385 |
Multiple organ dysfunction syndrome | 96.27 | 11.38 | 166 | 44917 | 50171 | 50509870 |
Completed suicide | 93.79 | 11.38 | 6 | 45077 | 131883 | 50428158 |
Pemphigus | 93.45 | 11.38 | 3 | 45080 | 120163 | 50439878 |
Product use in unapproved indication | 93.21 | 11.38 | 270 | 44813 | 115549 | 50444492 |
Cerebral infarction | 92.47 | 11.38 | 105 | 44978 | 21499 | 50538542 |
Premature baby | 90.42 | 11.38 | 96 | 44987 | 18241 | 50541800 |
Haemoperitoneum | 88.61 | 11.38 | 44 | 45039 | 2511 | 50557530 |
Activated partial thromboplastin time prolonged | 82.26 | 11.38 | 58 | 45025 | 6344 | 50553697 |
Haematoma muscle | 81.87 | 11.38 | 29 | 45054 | 699 | 50559342 |
Cardiogenic shock | 81.08 | 11.38 | 84 | 44999 | 15515 | 50544526 |
Compartment syndrome | 80.40 | 11.38 | 38 | 45045 | 1944 | 50558097 |
Spinal epidural haematoma | 80.27 | 11.38 | 31 | 45052 | 958 | 50559083 |
Pain | 78.39 | 11.38 | 260 | 44823 | 578643 | 49981398 |
Cardiac arrest | 78.17 | 11.38 | 206 | 44877 | 83445 | 50476596 |
Haemothorax | 77.63 | 11.38 | 37 | 45046 | 1929 | 50558112 |
Abdominal discomfort | 76.28 | 11.38 | 57 | 45026 | 231584 | 50328457 |
Systemic lupus erythematosus | 74.45 | 11.38 | 17 | 45066 | 140605 | 50419436 |
Pharyngeal haemorrhage | 74.39 | 11.38 | 25 | 45058 | 512 | 50559529 |
Aplastic anaemia | 70.56 | 11.38 | 57 | 45026 | 7646 | 50552395 |
Off label use | 70.17 | 11.38 | 687 | 44396 | 473739 | 50086302 |
Toxic epidermal necrolysis | 70.17 | 11.38 | 90 | 44993 | 20902 | 50539139 |
Foetal death | 65.51 | 11.38 | 56 | 45027 | 8124 | 50551917 |
Low birth weight baby | 63.58 | 11.38 | 48 | 45035 | 5833 | 50554208 |
Cardiac tamponade | 63.03 | 11.38 | 42 | 45041 | 4190 | 50555851 |
Heparin-induced thrombocytopenia test positive | 62.86 | 11.38 | 11 | 45072 | 4 | 50560037 |
Subdural haematoma | 62.45 | 11.38 | 67 | 45016 | 12880 | 50547161 |
Hypotension | 61.98 | 11.38 | 390 | 44693 | 235079 | 50324962 |
Subarachnoid haemorrhage | 57.76 | 11.38 | 59 | 45024 | 10717 | 50549324 |
Infective aneurysm | 56.96 | 11.38 | 19 | 45064 | 380 | 50559661 |
Disseminated intravascular coagulation | 56.54 | 11.38 | 73 | 45010 | 17062 | 50542979 |
Embolism | 56.41 | 11.38 | 48 | 45035 | 6920 | 50553121 |
Sepsis | 56.17 | 11.38 | 251 | 44832 | 132674 | 50427367 |
Haemoglobin decreased | 54.34 | 11.38 | 241 | 44842 | 126975 | 50433066 |
Wound | 53.63 | 11.38 | 14 | 45069 | 105780 | 50454261 |
Hypersensitivity | 52.35 | 11.38 | 69 | 45014 | 215092 | 50344949 |
Drug ineffective | 52.02 | 11.38 | 474 | 44609 | 818859 | 49741182 |
Pericarditis | 51.95 | 11.38 | 5 | 45078 | 78684 | 50481357 |
Coronary artery thrombosis | 51.24 | 11.38 | 23 | 45060 | 1044 | 50558997 |
Respiratory failure | 51.12 | 11.38 | 188 | 44895 | 90993 | 50469048 |
Peripheral ischaemia | 50.94 | 11.38 | 37 | 45046 | 4239 | 50555802 |
Hypoxia | 50.93 | 11.38 | 129 | 44954 | 50994 | 50509047 |
Coagulation time shortened | 50.81 | 11.38 | 14 | 45069 | 141 | 50559900 |
Caesarean section | 50.62 | 11.38 | 66 | 45017 | 15573 | 50544468 |
Acute motor-sensory axonal neuropathy | 50.39 | 11.38 | 16 | 45067 | 272 | 50559769 |
Eosinophilia | 50.22 | 11.38 | 72 | 45011 | 18580 | 50541461 |
Choroidal infarction | 48.86 | 11.38 | 12 | 45071 | 73 | 50559968 |
Subchorionic haematoma | 48.59 | 11.38 | 13 | 45070 | 116 | 50559925 |
Fatigue | 48.12 | 11.38 | 402 | 44681 | 707199 | 49852842 |
Deep vein thrombosis | 47.89 | 11.38 | 159 | 44924 | 73145 | 50486896 |
Treatment failure | 46.39 | 11.38 | 33 | 45050 | 137604 | 50422437 |
Procedural haemorrhage | 46.28 | 11.38 | 28 | 45055 | 2362 | 50557679 |
Coagulation time prolonged | 46.17 | 11.38 | 22 | 45061 | 1146 | 50558895 |
Intracardiac thrombus | 45.91 | 11.38 | 27 | 45056 | 2162 | 50557879 |
Encephalopathy | 45.64 | 11.38 | 96 | 44987 | 33615 | 50526426 |
Weight increased | 44.89 | 11.38 | 69 | 45014 | 201822 | 50358219 |
Gastrointestinal haemorrhage | 44.35 | 11.38 | 155 | 44928 | 73166 | 50486875 |
Orbital compartment syndrome | 44.35 | 11.38 | 9 | 45074 | 18 | 50560023 |
Adrenal haemorrhage | 44.32 | 11.38 | 16 | 45067 | 408 | 50559633 |
Psoriasis | 43.96 | 11.38 | 5 | 45078 | 68995 | 50491046 |
Skin necrosis | 43.44 | 11.38 | 51 | 45032 | 10816 | 50549225 |
Muscle haemorrhage | 43.20 | 11.38 | 29 | 45054 | 2929 | 50557112 |
Musculoskeletal stiffness | 43.05 | 11.38 | 31 | 45052 | 128450 | 50431591 |
Arthritis | 42.96 | 11.38 | 12 | 45071 | 86709 | 50473332 |
Rash | 42.55 | 11.38 | 223 | 44860 | 437248 | 50122793 |
Nasopharyngitis | 41.88 | 11.38 | 67 | 45016 | 192860 | 50367181 |
Pulmonary alveolar haemorrhage | 41.62 | 11.38 | 32 | 45051 | 3995 | 50556046 |
Acute myocardial infarction | 41.55 | 11.38 | 85 | 44998 | 29188 | 50530853 |
Swelling | 41.53 | 11.38 | 72 | 45011 | 200800 | 50359241 |
Intentional overdose | 41.18 | 11.38 | 4 | 45079 | 62500 | 50497541 |
Foetal exposure during pregnancy | 40.69 | 11.38 | 81 | 45002 | 27278 | 50532763 |
Injection site pain | 39.59 | 11.38 | 25 | 45058 | 110999 | 50449042 |
Coagulopathy | 39.41 | 11.38 | 63 | 45020 | 17881 | 50542160 |
Blood pressure decreased | 38.97 | 11.38 | 124 | 44959 | 55785 | 50504256 |
Lower respiratory tract infection | 38.96 | 11.38 | 18 | 45065 | 95183 | 50464858 |
Anaemia | 38.83 | 11.38 | 369 | 44714 | 252087 | 50307954 |
Cerebral haematoma | 38.74 | 11.38 | 28 | 45055 | 3183 | 50556858 |
Platelet aggregation inhibition | 38.72 | 11.38 | 11 | 45072 | 125 | 50559916 |
Pulmonary infarction | 38.64 | 11.38 | 25 | 45058 | 2373 | 50557668 |
HELLP syndrome | 38.45 | 11.38 | 18 | 45065 | 901 | 50559140 |
Ischaemic stroke | 37.82 | 11.38 | 58 | 45025 | 15890 | 50544151 |
Gait disturbance | 37.61 | 11.38 | 47 | 45036 | 149958 | 50410083 |
Cardiac valve replacement complication | 37.44 | 11.38 | 11 | 45072 | 142 | 50559899 |
Brain herniation | 37.39 | 11.38 | 27 | 45056 | 3065 | 50556976 |
Gangrene | 37.32 | 11.38 | 32 | 45051 | 4660 | 50555381 |
Spinal cord compression | 37.30 | 11.38 | 29 | 45054 | 3680 | 50556361 |
Rectosigmoid cancer | 36.95 | 11.38 | 11 | 45072 | 149 | 50559892 |
Venous thrombosis | 36.63 | 11.38 | 31 | 45052 | 4435 | 50555606 |
Toxoplasmosis | 36.52 | 11.38 | 20 | 45063 | 1397 | 50558644 |
Drug abuse | 36.51 | 11.38 | 5 | 45078 | 59841 | 50500200 |
Discomfort | 36.50 | 11.38 | 26 | 45057 | 108354 | 50451687 |
Toxicity to various agents | 36.37 | 11.38 | 85 | 44998 | 212414 | 50347627 |
Ocular retrobulbar haemorrhage | 36.26 | 11.38 | 10 | 45073 | 101 | 50559940 |
Mobility decreased | 36.15 | 11.38 | 13 | 45070 | 79935 | 50480106 |
Hepatic enzyme increased | 35.54 | 11.38 | 42 | 45041 | 137338 | 50422703 |
Haemorrhagic transformation stroke | 35.24 | 11.38 | 18 | 45065 | 1091 | 50558950 |
Platelet count decreased | 35.12 | 11.38 | 180 | 44903 | 100546 | 50459495 |
Mixed liver injury | 34.74 | 11.38 | 27 | 45056 | 3424 | 50556617 |
Thrombotic microangiopathy | 34.72 | 11.38 | 41 | 45042 | 8750 | 50551291 |
Spinal subdural haematoma | 34.63 | 11.38 | 10 | 45073 | 121 | 50559920 |
Electrocardiogram ST segment elevation | 34.59 | 11.38 | 27 | 45056 | 3446 | 50556595 |
Aortic thrombosis | 34.20 | 11.38 | 17 | 45066 | 972 | 50559069 |
Loss of personal independence in daily activities | 34.13 | 11.38 | 10 | 45073 | 70040 | 50490001 |
Oesophageal intramural haematoma | 34.08 | 11.38 | 9 | 45074 | 76 | 50559965 |
Splenic rupture | 33.93 | 11.38 | 18 | 45065 | 1180 | 50558861 |
Rash maculo-papular | 33.91 | 11.38 | 74 | 45009 | 26567 | 50533474 |
Hypercoagulation | 33.63 | 11.38 | 21 | 45062 | 1874 | 50558167 |
Depression | 33.54 | 11.38 | 60 | 45023 | 165363 | 50394678 |
Product dose omission issue | 33.53 | 11.38 | 71 | 45012 | 183767 | 50376274 |
Hyperlactacidaemia | 33.50 | 11.38 | 23 | 45060 | 2410 | 50557631 |
Stevens-Johnson syndrome | 33.07 | 11.38 | 65 | 45018 | 21687 | 50538354 |
Suicidal ideation | 32.92 | 11.38 | 5 | 45078 | 55380 | 50504661 |
Blood cholesterol increased | 32.78 | 11.38 | 5 | 45078 | 55210 | 50504831 |
Malaise | 32.60 | 11.38 | 171 | 44912 | 335361 | 50224680 |
Antiphospholipid syndrome | 32.58 | 11.38 | 19 | 45064 | 1498 | 50558543 |
Vena cava thrombosis | 32.39 | 11.38 | 21 | 45062 | 2000 | 50558041 |
Tonsillar haemorrhage | 32.25 | 11.38 | 11 | 45072 | 236 | 50559805 |
Tachypnoea | 31.77 | 11.38 | 51 | 45032 | 14526 | 50545515 |
Puncture site haemorrhage | 31.49 | 11.38 | 11 | 45072 | 254 | 50559787 |
Paraplegia | 30.99 | 11.38 | 22 | 45061 | 2432 | 50557609 |
Pericardial haemorrhage | 30.62 | 11.38 | 18 | 45065 | 1440 | 50558601 |
Transcription medication error | 30.60 | 11.38 | 10 | 45073 | 187 | 50559854 |
Contraindicated product administered | 30.22 | 11.38 | 54 | 45029 | 148904 | 50411137 |
Product administration error | 30.11 | 11.38 | 59 | 45024 | 19640 | 50540401 |
Suicide attempt | 30 | 11.38 | 5 | 45078 | 51727 | 50508314 |
Incorrect drug administration rate | 29.80 | 11.38 | 22 | 45061 | 2584 | 50557457 |
Irritable bowel syndrome | 29.77 | 11.38 | 5 | 45078 | 51436 | 50508605 |
Septic shock | 29.63 | 11.38 | 115 | 44968 | 57060 | 50502981 |
Therapeutic product effect incomplete | 29.46 | 11.38 | 23 | 45060 | 91492 | 50468549 |
Shock | 29.35 | 11.38 | 60 | 45023 | 20590 | 50539451 |
Insomnia | 29.07 | 11.38 | 71 | 45012 | 174794 | 50385247 |
Intraventricular haemorrhage | 28.92 | 11.38 | 19 | 45064 | 1851 | 50558190 |
Post procedural haemorrhage | 28.86 | 11.38 | 34 | 45049 | 7236 | 50552805 |
Impaired healing | 28.85 | 11.38 | 13 | 45070 | 69773 | 50490268 |
Oliguria | 28.68 | 11.38 | 36 | 45047 | 8180 | 50551861 |
Embolic cerebral infarction | 28.44 | 11.38 | 12 | 45071 | 468 | 50559573 |
Intracranial haematoma | 28.36 | 11.38 | 11 | 45072 | 344 | 50559697 |
Catheter site haemorrhage | 28.32 | 11.38 | 22 | 45061 | 2788 | 50557253 |
Drug chemical incompatibility | 28.31 | 11.38 | 7 | 45076 | 44 | 50559997 |
Hypervolaemia | 28.21 | 11.38 | 67 | 45016 | 25432 | 50534609 |
Ill-defined disorder | 28.13 | 11.38 | 7 | 45076 | 54647 | 50505394 |
Premature rupture of membranes | 28.11 | 11.38 | 27 | 45056 | 4553 | 50555488 |
Haemorrhagic infarction | 27.70 | 11.38 | 10 | 45073 | 255 | 50559786 |
Arterial thrombosis | 27.44 | 11.38 | 16 | 45067 | 1261 | 50558780 |
Respiratory distress | 27.35 | 11.38 | 74 | 45009 | 30415 | 50529626 |
Anti factor Xa activity decreased | 27.19 | 11.38 | 5 | 45078 | 4 | 50560037 |
Hemiparesis | 27.02 | 11.38 | 57 | 45026 | 19991 | 50540050 |
Intra-abdominal haematoma | 26.99 | 11.38 | 17 | 45066 | 1540 | 50558501 |
Memory impairment | 26.76 | 11.38 | 19 | 45064 | 79341 | 50480700 |
Haemodynamic instability | 26.18 | 11.38 | 34 | 45049 | 7990 | 50552051 |
Ventricular tachycardia | 26.16 | 11.38 | 49 | 45034 | 15772 | 50544269 |
Peripheral artery thrombosis | 25.81 | 11.38 | 17 | 45066 | 1663 | 50558378 |
Choroidal effusion | 25.74 | 11.38 | 11 | 45072 | 443 | 50559598 |
Pulseless electrical activity | 25.53 | 11.38 | 31 | 45052 | 6810 | 50553231 |
Vasodilatation | 25.52 | 11.38 | 19 | 45064 | 2260 | 50557781 |
Peripheral swelling | 25.37 | 11.38 | 96 | 44987 | 205840 | 50354201 |
Haemolysis | 25.33 | 11.38 | 29 | 45054 | 5987 | 50554054 |
Atrial thrombosis | 25.29 | 11.38 | 16 | 45067 | 1461 | 50558580 |
Cholestasis | 25.19 | 11.38 | 64 | 45019 | 25337 | 50534704 |
Febrile neutropenia | 25.15 | 11.38 | 161 | 44922 | 97506 | 50462535 |
Cerebellar haemorrhage | 24.98 | 11.38 | 15 | 45068 | 1248 | 50558793 |
Acute generalised exanthematous pustulosis | 24.79 | 11.38 | 35 | 45048 | 8903 | 50551138 |
Asthma | 24.53 | 11.38 | 26 | 45057 | 89311 | 50470730 |
Arterial haemorrhage | 24.52 | 11.38 | 16 | 45067 | 1541 | 50558500 |
Normal newborn | 24.45 | 11.38 | 30 | 45053 | 6661 | 50553380 |
Cerebral amyloid angiopathy | 24.36 | 11.38 | 8 | 45075 | 152 | 50559889 |
Injection site swelling | 24.31 | 11.38 | 4 | 45079 | 41769 | 50518272 |
Abdominal compartment syndrome | 23.79 | 11.38 | 11 | 45072 | 535 | 50559506 |
Lipoedema | 23.74 | 11.38 | 9 | 45074 | 264 | 50559777 |
Osteoarthritis | 23.70 | 11.38 | 16 | 45067 | 68590 | 50491451 |
Arterial intramural haematoma | 23.46 | 11.38 | 5 | 45078 | 14 | 50560027 |
Foetal growth restriction | 23.07 | 11.38 | 29 | 45054 | 6598 | 50553443 |
Spinal cord disorder | 23.01 | 11.38 | 14 | 45069 | 1193 | 50558848 |
Product measured potency issue | 22.86 | 11.38 | 7 | 45076 | 105 | 50559936 |
Renal vein thrombosis | 22.83 | 11.38 | 9 | 45074 | 294 | 50559747 |
Haemorrhage subcutaneous | 22.67 | 11.38 | 19 | 45064 | 2682 | 50557359 |
Pituitary apoplexy | 22.27 | 11.38 | 7 | 45076 | 115 | 50559926 |
Intentional product misuse | 22.17 | 11.38 | 7 | 45076 | 46727 | 50513314 |
Stress cardiomyopathy | 22.05 | 11.38 | 31 | 45052 | 7856 | 50552185 |
Cerebral venous thrombosis | 21.86 | 11.38 | 16 | 45067 | 1855 | 50558186 |
Acute respiratory distress syndrome | 21.80 | 11.38 | 54 | 45029 | 21045 | 50538996 |
Ventricular fibrillation | 21.73 | 11.38 | 36 | 45047 | 10523 | 50549518 |
Intra-abdominal haemorrhage | 21.55 | 11.38 | 17 | 45066 | 2203 | 50557838 |
Paratonia | 21.53 | 11.38 | 5 | 45078 | 23 | 50560018 |
Renal infarct | 21.47 | 11.38 | 14 | 45069 | 1346 | 50558695 |
Vaginal haemorrhage | 21.44 | 11.38 | 59 | 45024 | 24492 | 50535549 |
Cerebral reperfusion injury | 21.33 | 11.38 | 4 | 45079 | 4 | 50560037 |
Therapeutic product effect decreased | 21.25 | 11.38 | 57 | 45026 | 135993 | 50424048 |
Suspected transmission of an infectious agent via product | 21.19 | 11.38 | 8 | 45075 | 232 | 50559809 |
Dizziness | 21.11 | 11.38 | 202 | 44881 | 346167 | 50213874 |
Peritoneal haematoma | 20.90 | 11.38 | 6 | 45077 | 71 | 50559970 |
Stillbirth | 20.65 | 11.38 | 26 | 45057 | 5926 | 50554115 |
Postpartum haemorrhage | 20.49 | 11.38 | 15 | 45068 | 1739 | 50558302 |
Product contamination | 20.31 | 11.38 | 10 | 45073 | 560 | 50559481 |
Weight decreased | 20.22 | 11.38 | 115 | 44968 | 221130 | 50338911 |
Confusional state | 20.20 | 11.38 | 91 | 44992 | 185837 | 50374204 |
Acute respiratory failure | 20.20 | 11.38 | 64 | 45019 | 28718 | 50531323 |
Coagulation time abnormal | 20.17 | 11.38 | 6 | 45077 | 81 | 50559960 |
Subcapsular renal haematoma | 20.16 | 11.38 | 8 | 45075 | 266 | 50559775 |
Gastrooesophageal reflux disease | 20.15 | 11.38 | 23 | 45060 | 76405 | 50483636 |
Coronary artery perforation | 20.14 | 11.38 | 5 | 45078 | 32 | 50560009 |
Vascular access site haemorrhage | 20.06 | 11.38 | 4 | 45079 | 7 | 50560034 |
Haematuria | 19.88 | 11.38 | 59 | 45024 | 25554 | 50534487 |
Protein C decreased | 19.88 | 11.38 | 5 | 45078 | 34 | 50560007 |
Hepatic haematoma | 19.80 | 11.38 | 9 | 45074 | 421 | 50559620 |
Drug reaction with eosinophilia and systemic symptoms | 19.76 | 11.38 | 63 | 45020 | 28361 | 50531680 |
Splenic infarction | 19.73 | 11.38 | 14 | 45069 | 1546 | 50558495 |
Atheroembolism | 19.71 | 11.38 | 4 | 45079 | 8 | 50560033 |
Kidney rupture | 19.63 | 11.38 | 5 | 45078 | 36 | 50560005 |
Blood pressure fluctuation | 19.62 | 11.38 | 4 | 45079 | 35819 | 50524222 |
Myalgia | 19.48 | 11.38 | 52 | 45031 | 124267 | 50435774 |
Feeling abnormal | 19.28 | 11.38 | 53 | 45030 | 125439 | 50434602 |
Injection site erythema | 19.27 | 11.38 | 23 | 45060 | 74913 | 50485128 |
Myelomalacia | 19.17 | 11.38 | 5 | 45078 | 40 | 50560001 |
Organic brain syndrome | 19.12 | 11.38 | 7 | 45076 | 186 | 50559855 |
Live birth | 19.11 | 11.38 | 44 | 45039 | 16364 | 50543677 |
Haemoptysis | 18.99 | 11.38 | 58 | 45025 | 25515 | 50534526 |
Calciphylaxis | 18.99 | 11.38 | 17 | 45066 | 2621 | 50557420 |
Haemodialysis complication | 18.77 | 11.38 | 7 | 45076 | 196 | 50559845 |
Cardiac failure | 18.74 | 11.38 | 124 | 44959 | 75916 | 50484125 |
Inflammation | 18.70 | 11.38 | 14 | 45069 | 56898 | 50503143 |
Platelet transfusion | 18.67 | 11.38 | 10 | 45073 | 668 | 50559373 |
Gastrointestinal disorder | 18.47 | 11.38 | 35 | 45048 | 94421 | 50465620 |
Pain in extremity | 18.43 | 11.38 | 155 | 44928 | 272710 | 50287331 |
Premature labour | 18.30 | 11.38 | 35 | 45048 | 11441 | 50548600 |
Device related infection | 18.27 | 11.38 | 50 | 45033 | 20685 | 50539356 |
Blood albumin decreased | 18.27 | 11.38 | 38 | 45045 | 13198 | 50546843 |
Bullous haemorrhagic dermatosis | 18.09 | 11.38 | 5 | 45078 | 51 | 50559990 |
Ureteric haemorrhage | 18.07 | 11.38 | 3 | 45080 | 0 | 50560041 |
Cerebellar embolism | 18.07 | 11.38 | 3 | 45080 | 0 | 50560041 |
Hand amputation | 18.07 | 11.38 | 3 | 45080 | 0 | 50560041 |
Phaeochromocytoma crisis | 18.01 | 11.38 | 7 | 45076 | 220 | 50559821 |
Transfusion | 17.75 | 11.38 | 37 | 45046 | 12868 | 50547173 |
Hemiplegia | 17.72 | 11.38 | 27 | 45056 | 7354 | 50552687 |
Gestational hypertension | 17.65 | 11.38 | 15 | 45068 | 2158 | 50557883 |
Injection site pruritus | 17.55 | 11.38 | 7 | 45076 | 40404 | 50519637 |
Mucosal erosion | 17.33 | 11.38 | 12 | 45071 | 1275 | 50558766 |
Arm amputation | 17.29 | 11.38 | 4 | 45079 | 18 | 50560023 |
Ischaemic hepatitis | 17.09 | 11.38 | 14 | 45069 | 1915 | 50558126 |
Product administered to patient of inappropriate age | 17.08 | 11.38 | 16 | 45067 | 2614 | 50557427 |
Posthaemorrhagic hydrocephalus | 16.95 | 11.38 | 4 | 45079 | 20 | 50560021 |
Procedural complication | 16.62 | 11.38 | 21 | 45062 | 4802 | 50555239 |
Wrong technique in product usage process | 16.57 | 11.38 | 15 | 45068 | 55495 | 50504546 |
Cholestatic liver injury | 16.52 | 11.38 | 14 | 45069 | 2007 | 50558034 |
Injection site plaque | 16.39 | 11.38 | 5 | 45078 | 74 | 50559967 |
Capillary fragility test | 16.34 | 11.38 | 4 | 45079 | 24 | 50560017 |
Nervous system disorder | 16.21 | 11.38 | 41 | 45042 | 16182 | 50543859 |
Anticoagulation drug level below therapeutic | 16.13 | 11.38 | 9 | 45074 | 652 | 50559389 |
Hyperkalaemia | 16.10 | 11.38 | 85 | 44998 | 48004 | 50512037 |
Aneurysm recanalisation | 16.00 | 11.38 | 3 | 45080 | 3 | 50560038 |
Pre-eclampsia | 15.99 | 11.38 | 27 | 45056 | 8017 | 50552024 |
COVID-19 | 15.98 | 11.38 | 83 | 45000 | 46579 | 50513462 |
Neurological symptom | 15.87 | 11.38 | 20 | 45063 | 4562 | 50555479 |
Thrombolysis | 15.80 | 11.38 | 5 | 45078 | 84 | 50559957 |
Dry gangrene | 15.72 | 11.38 | 8 | 45075 | 481 | 50559560 |
Post procedural haematoma | 15.55 | 11.38 | 11 | 45072 | 1209 | 50558832 |
Hepatic function abnormal | 15.54 | 11.38 | 64 | 45019 | 32617 | 50527424 |
Cerebrovascular disorder | 15.45 | 11.38 | 15 | 45068 | 2563 | 50557478 |
Renal failure | 15.43 | 11.38 | 154 | 44929 | 106479 | 50453562 |
Herpes simplex hepatitis | 15.43 | 11.38 | 7 | 45076 | 326 | 50559715 |
Patent ductus arteriosus | 15.39 | 11.38 | 18 | 45065 | 3802 | 50556239 |
Protein S decreased | 15.34 | 11.38 | 4 | 45079 | 32 | 50560009 |
Pseudomonas infection | 15.34 | 11.38 | 29 | 45054 | 9401 | 50550640 |
Pelvic haematoma | 15.23 | 11.38 | 8 | 45075 | 514 | 50559527 |
Hydrocephalus | 15.17 | 11.38 | 20 | 45063 | 4768 | 50555273 |
Foetal exposure timing unspecified | 15.16 | 11.38 | 6 | 45077 | 198 | 50559843 |
Folliculitis | 15.16 | 11.38 | 8 | 45075 | 39217 | 50520824 |
Medical device site thrombosis | 15.14 | 11.38 | 3 | 45080 | 5 | 50560036 |
Pulse absent | 15.11 | 11.38 | 20 | 45063 | 4786 | 50555255 |
Recurrence of neuromuscular blockade | 15.08 | 11.38 | 5 | 45078 | 98 | 50559943 |
Petechiae | 15.07 | 11.38 | 34 | 45049 | 12478 | 50547563 |
Cerebral artery thrombosis | 15.03 | 11.38 | 7 | 45076 | 346 | 50559695 |
Medical device site haemorrhage | 15.02 | 11.38 | 4 | 45079 | 35 | 50560006 |
Obstructive shock | 15.02 | 11.38 | 4 | 45079 | 35 | 50560006 |
Cerebral artery embolism | 14.95 | 11.38 | 9 | 45074 | 752 | 50559289 |
Spinal cord haemorrhage | 14.94 | 11.38 | 6 | 45077 | 206 | 50559835 |
Therapeutic product effect increased | 14.93 | 11.38 | 10 | 45073 | 1006 | 50559035 |
Jugular vein thrombosis | 14.88 | 11.38 | 15 | 45068 | 2681 | 50557360 |
Haemoglobin abnormal | 14.87 | 11.38 | 19 | 45064 | 4393 | 50555648 |
Type 2 diabetes mellitus | 14.85 | 11.38 | 6 | 45077 | 34369 | 50525672 |
Blood creatine increased | 14.85 | 11.38 | 20 | 45063 | 4867 | 50555174 |
Heparin-induced thrombocytopenia test | 14.78 | 11.38 | 3 | 45080 | 6 | 50560035 |
Vascular parkinsonism | 14.72 | 11.38 | 5 | 45078 | 106 | 50559935 |
Spontaneous haematoma | 14.68 | 11.38 | 9 | 45074 | 777 | 50559264 |
Infection | 14.68 | 11.38 | 92 | 44991 | 172862 | 50387179 |
Threatened labour | 14.67 | 11.38 | 9 | 45074 | 778 | 50559263 |
Plantar erythema | 14.65 | 11.38 | 6 | 45077 | 217 | 50559824 |
Cytokine release syndrome | 14.60 | 11.38 | 27 | 45056 | 8607 | 50551434 |
Agranulocytosis | 14.45 | 11.38 | 47 | 45036 | 21374 | 50538667 |
Serratia infection | 14.43 | 11.38 | 9 | 45074 | 801 | 50559240 |
Renal haemorrhage | 14.42 | 11.38 | 9 | 45074 | 802 | 50559239 |
Electrocardiogram T wave alternans | 14.37 | 11.38 | 4 | 45079 | 42 | 50559999 |
Peritonitis | 14.30 | 11.38 | 38 | 45045 | 15448 | 50544593 |
International normalised ratio increased | 14.26 | 11.38 | 76 | 45007 | 43076 | 50516965 |
Hepatic infarction | 14.23 | 11.38 | 8 | 45075 | 588 | 50559453 |
Eosinophil cationic protein increased | 14.20 | 11.38 | 4 | 45079 | 44 | 50559997 |
Diarrhoea | 14.12 | 11.38 | 408 | 44675 | 588068 | 49971973 |
Adverse event | 14.08 | 11.38 | 11 | 45072 | 43752 | 50516289 |
Spinal cord oedema | 14.02 | 11.38 | 5 | 45078 | 123 | 50559918 |
Haemorrhagic cerebral infarction | 13.99 | 11.38 | 8 | 45075 | 608 | 50559433 |
Balance disorder | 13.94 | 11.38 | 26 | 45057 | 70564 | 50489477 |
Melaena | 13.89 | 11.38 | 54 | 45029 | 26810 | 50533231 |
Fungal sepsis | 13.78 | 11.38 | 10 | 45073 | 1144 | 50558897 |
Injury | 13.70 | 11.38 | 14 | 45069 | 48911 | 50511130 |
Mouth ulceration | 13.65 | 11.38 | 4 | 45079 | 28020 | 50532021 |
Anticoagulation drug level above therapeutic | 13.64 | 11.38 | 10 | 45073 | 1162 | 50558879 |
Pulmonary artery thrombosis | 13.62 | 11.38 | 8 | 45075 | 639 | 50559402 |
Breast cancer | 13.52 | 11.38 | 11 | 45072 | 42879 | 50517162 |
Enterococcal infection | 13.50 | 11.38 | 23 | 45060 | 6875 | 50553166 |
Thrombin time abnormal | 13.46 | 11.38 | 3 | 45080 | 11 | 50560030 |
Tachycardia | 13.45 | 11.38 | 142 | 44941 | 99621 | 50460420 |
Device related sepsis | 13.38 | 11.38 | 16 | 45067 | 3459 | 50556582 |
Fistula discharge | 13.21 | 11.38 | 9 | 45074 | 931 | 50559110 |
Stoma site haemorrhage | 13.20 | 11.38 | 9 | 45074 | 932 | 50559109 |
Pulmonary haemorrhage | 13.18 | 11.38 | 22 | 45061 | 6470 | 50553571 |
Eschar | 13.16 | 11.38 | 7 | 45076 | 461 | 50559580 |
Adverse drug reaction | 13.11 | 11.38 | 18 | 45065 | 55204 | 50504837 |
Rhinorrhoea | 13.08 | 11.38 | 16 | 45067 | 51567 | 50508474 |
Cardiac ventricular thrombosis | 12.91 | 11.38 | 7 | 45076 | 479 | 50559562 |
Hypovolaemia | 12.86 | 11.38 | 27 | 45056 | 9438 | 50550603 |
Subdural haemorrhage | 12.86 | 11.38 | 14 | 45069 | 2735 | 50557306 |
Pulmonary oedema | 12.79 | 11.38 | 81 | 45002 | 48857 | 50511184 |
Coronary artery dissection | 12.76 | 11.38 | 8 | 45075 | 719 | 50559322 |
Seizure like phenomena | 12.72 | 11.38 | 9 | 45074 | 989 | 50559052 |
Cataract | 12.72 | 11.38 | 14 | 45069 | 47286 | 50512755 |
Haematidrosis | 12.71 | 11.38 | 4 | 45079 | 66 | 50559975 |
Dry mouth | 12.66 | 11.38 | 19 | 45064 | 56159 | 50503882 |
Ventricular enlargement | 12.65 | 11.38 | 4 | 45079 | 67 | 50559974 |
Leg amputation | 12.60 | 11.38 | 12 | 45071 | 2001 | 50558040 |
Peritonitis bacterial | 12.56 | 11.38 | 18 | 45065 | 4643 | 50555398 |
Blood creatinine increased | 12.51 | 11.38 | 113 | 44970 | 76047 | 50483994 |
Arterial rupture | 12.41 | 11.38 | 6 | 45077 | 323 | 50559718 |
Anxiety | 12.38 | 11.38 | 100 | 44983 | 177506 | 50382535 |
Haemorrhagic stroke | 12.37 | 11.38 | 19 | 45064 | 5209 | 50554832 |
Wound haematoma | 12.33 | 11.38 | 4 | 45079 | 73 | 50559968 |
Sleep disorder | 12.31 | 11.38 | 20 | 45063 | 57263 | 50502778 |
Abortion early | 12.25 | 11.38 | 3 | 45080 | 18 | 50560023 |
Pulse waveform abnormal | 12.18 | 11.38 | 4 | 45079 | 76 | 50559965 |
Ischaemia | 12.17 | 11.38 | 17 | 45066 | 4280 | 50555761 |
Muscle spasms | 12.15 | 11.38 | 64 | 45019 | 125489 | 50434552 |
Ankle brachial index decreased | 12.13 | 11.38 | 4 | 45079 | 77 | 50559964 |
Basal ganglia haemorrhage | 12.11 | 11.38 | 7 | 45076 | 543 | 50559498 |
Clostridium difficile colitis | 12.04 | 11.38 | 39 | 45044 | 17703 | 50542338 |
Central venous catheterisation | 12.03 | 11.38 | 12 | 45071 | 2118 | 50557923 |
Fall | 12.03 | 11.38 | 218 | 44865 | 334714 | 50225327 |
Colorectal cancer | 12.02 | 11.38 | 10 | 45073 | 1397 | 50558644 |
Adrenomegaly | 11.98 | 11.38 | 3 | 45080 | 20 | 50560021 |
Limbal swelling | 11.98 | 11.38 | 3 | 45080 | 20 | 50560021 |
Blood loss anaemia | 11.98 | 11.38 | 24 | 45059 | 8115 | 50551926 |
Carotid intima-media thickness increased | 11.94 | 11.38 | 4 | 45079 | 81 | 50559960 |
Procedural hypotension | 11.92 | 11.38 | 9 | 45074 | 1093 | 50558948 |
Cytomegalovirus enterocolitis | 11.89 | 11.38 | 7 | 45076 | 562 | 50559479 |
Adenocarcinoma of colon | 11.88 | 11.38 | 12 | 45071 | 2150 | 50557891 |
Breast haematoma | 11.85 | 11.38 | 5 | 45078 | 195 | 50559846 |
Toxic skin eruption | 11.84 | 11.38 | 29 | 45054 | 11222 | 50548819 |
Splenic haemorrhage | 11.83 | 11.38 | 5 | 45078 | 196 | 50559845 |
Gastrointestinal necrosis | 11.75 | 11.38 | 13 | 45070 | 2585 | 50557456 |
Blister | 11.73 | 11.38 | 38 | 45045 | 85380 | 50474661 |
Drug-device interaction | 11.72 | 11.38 | 4 | 45079 | 86 | 50559955 |
Toxic encephalopathy | 11.61 | 11.38 | 19 | 45064 | 5496 | 50554545 |
Epistaxis | 11.61 | 11.38 | 97 | 44986 | 63857 | 50496184 |
Cerebral artery occlusion | 11.53 | 11.38 | 8 | 45075 | 852 | 50559189 |
Atrial fibrillation | 11.53 | 11.38 | 140 | 44943 | 101605 | 50458436 |
Renal artery thrombosis | 11.47 | 11.38 | 4 | 45079 | 92 | 50559949 |
Bleeding time prolonged | 11.47 | 11.38 | 7 | 45076 | 600 | 50559441 |
COVID-19 pneumonia | 11.47 | 11.38 | 24 | 45059 | 8371 | 50551670 |
Acute pulmonary oedema | 11.39 | 11.38 | 22 | 45061 | 7245 | 50552796 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Heparin-induced thrombocytopenia | 2894.06 | 12.30 | 792 | 44830 | 4187 | 29524718 |
Vascular stent thrombosis | 336.38 | 12.30 | 133 | 45489 | 2477 | 29526428 |
Thrombocytopenia | 248.58 | 12.30 | 603 | 45019 | 134220 | 29394685 |
Labelled drug-drug interaction medication error | 217.14 | 12.30 | 167 | 45455 | 11992 | 29516913 |
Haematoma | 206.55 | 12.30 | 215 | 45407 | 22997 | 29505908 |
Haemorrhage | 175.89 | 12.30 | 277 | 45345 | 44795 | 29484110 |
Cardiogenic shock | 162.25 | 12.30 | 173 | 45449 | 19017 | 29509888 |
Post procedural haemorrhage | 151.79 | 12.30 | 111 | 45511 | 7380 | 29521525 |
Shock haemorrhagic | 142.36 | 12.30 | 118 | 45504 | 9433 | 29519472 |
Haemorrhage intracranial | 138.94 | 12.30 | 140 | 45482 | 14402 | 29514503 |
Cerebral haemorrhage | 137.89 | 12.30 | 204 | 45418 | 31222 | 29497683 |
Multiple organ dysfunction syndrome | 132.04 | 12.30 | 297 | 45325 | 62819 | 29466086 |
Thrombosis | 129.99 | 12.30 | 236 | 45386 | 42809 | 29486096 |
Retroperitoneal haematoma | 126.08 | 12.30 | 65 | 45557 | 2293 | 29526612 |
Thrombosis in device | 124.02 | 12.30 | 71 | 45551 | 3093 | 29525812 |
Fatigue | 118.32 | 12.30 | 192 | 45430 | 316629 | 29212276 |
Appendicolith | 117.75 | 12.30 | 71 | 45551 | 3409 | 29525496 |
Coagulation time shortened | 113.98 | 12.30 | 32 | 45590 | 187 | 29528718 |
Cardiac tamponade | 113.21 | 12.30 | 77 | 45545 | 4558 | 29524347 |
Ventricular fibrillation | 103.63 | 12.30 | 125 | 45497 | 15708 | 29513197 |
Heparin resistance | 103.13 | 12.30 | 21 | 45601 | 16 | 29528889 |
Arterial thrombosis | 96.01 | 12.30 | 46 | 45576 | 1382 | 29527523 |
Drug abuse | 93.50 | 12.30 | 8 | 45614 | 79875 | 29449030 |
Septic shock | 91.51 | 12.30 | 257 | 45365 | 62303 | 29466602 |
Activated partial thromboplastin time prolonged | 89.91 | 12.30 | 83 | 45539 | 7659 | 29521246 |
Pulmonary embolism | 89.00 | 12.30 | 290 | 45332 | 76244 | 29452661 |
Brain herniation | 85.52 | 12.30 | 59 | 45563 | 3574 | 29525331 |
Appendicitis | 84.73 | 12.30 | 85 | 45537 | 8694 | 29520211 |
Off label use | 83.00 | 12.30 | 766 | 44856 | 300034 | 29228871 |
Arthralgia | 82.88 | 12.30 | 57 | 45565 | 139560 | 29389345 |
Drug reaction with eosinophilia and systemic symptoms | 82.60 | 12.30 | 152 | 45470 | 27840 | 29501065 |
Heparin-induced thrombocytopenia test positive | 79.43 | 12.30 | 21 | 45601 | 94 | 29528811 |
Subarachnoid haemorrhage | 75.99 | 12.30 | 84 | 45538 | 9608 | 29519297 |
Weight decreased | 74.26 | 12.30 | 74 | 45548 | 150831 | 29378074 |
Depression | 73.84 | 12.30 | 20 | 45602 | 85127 | 29443778 |
Toxicity to various agents | 72.67 | 12.30 | 97 | 45525 | 173564 | 29355341 |
Eosinophilia | 72.64 | 12.30 | 126 | 45496 | 22035 | 29506870 |
Coagulation time prolonged | 72.42 | 12.30 | 36 | 45586 | 1174 | 29527731 |
Intraventricular haemorrhage | 70.31 | 12.30 | 48 | 45574 | 2858 | 29526047 |
Retroperitoneal haemorrhage | 69.06 | 12.30 | 45 | 45577 | 2478 | 29526427 |
Death | 66.55 | 12.30 | 287 | 45335 | 341797 | 29187108 |
Coagulation time | 65.71 | 12.30 | 12 | 45610 | 0 | 29528905 |
Low birth weight baby | 63.80 | 12.30 | 64 | 45558 | 6544 | 29522361 |
Sepsis | 63.06 | 12.30 | 406 | 45216 | 142276 | 29386629 |
Intra-abdominal haemorrhage | 61.38 | 12.30 | 39 | 45583 | 2056 | 29526849 |
Disseminated intravascular coagulation | 60.84 | 12.30 | 110 | 45512 | 19870 | 29509035 |
Cardiac arrest | 60.51 | 12.30 | 277 | 45345 | 85314 | 29443591 |
Premature baby | 60.26 | 12.30 | 101 | 45521 | 17179 | 29511726 |
Haematoma muscle | 58.84 | 12.30 | 29 | 45593 | 928 | 29527977 |
Compartment syndrome | 58.14 | 12.30 | 40 | 45582 | 2412 | 29526493 |
Muscle haemorrhage | 57.43 | 12.30 | 45 | 45577 | 3317 | 29525588 |
Rash maculo-papular | 57.22 | 12.30 | 120 | 45502 | 24169 | 29504736 |
Deep vein thrombosis | 56.64 | 12.30 | 206 | 45416 | 57193 | 29471712 |
Product administration error | 55.82 | 12.30 | 88 | 45534 | 14222 | 29514683 |
Haemoglobin decreased | 55.20 | 12.30 | 320 | 45302 | 108055 | 29420850 |
Catheter site haemorrhage | 54.77 | 12.30 | 36 | 45586 | 2012 | 29526893 |
Diarrhoea | 54.29 | 12.30 | 297 | 45325 | 332401 | 29196504 |
Venous thrombosis | 54.27 | 12.30 | 42 | 45580 | 3040 | 29525865 |
Fall | 53.98 | 12.30 | 121 | 45501 | 177057 | 29351848 |
Acute kidney injury | 52.03 | 12.30 | 631 | 44991 | 264636 | 29264269 |
Asthenia | 51.27 | 12.30 | 166 | 45456 | 215084 | 29313821 |
Product use in unapproved indication | 50.56 | 12.30 | 266 | 45356 | 86609 | 29442296 |
Hypotension | 50.43 | 12.30 | 489 | 45133 | 193865 | 29335040 |
Haemodynamic instability | 50.00 | 12.30 | 62 | 45560 | 8011 | 29520894 |
Pericardial haemorrhage | 49.57 | 12.30 | 39 | 45583 | 2892 | 29526013 |
Procedural haemorrhage | 48.91 | 12.30 | 35 | 45587 | 2248 | 29526657 |
Intentional overdose | 47.51 | 12.30 | 3 | 45619 | 38525 | 29490380 |
Coagulation time abnormal | 47.23 | 12.30 | 15 | 45607 | 141 | 29528764 |
Pharyngeal haemorrhage | 46.35 | 12.30 | 22 | 45600 | 647 | 29528258 |
Haemothorax | 46.16 | 12.30 | 40 | 45582 | 3396 | 29525509 |
Coagulation test abnormal | 45.92 | 12.30 | 20 | 45602 | 479 | 29528426 |
Acute respiratory distress syndrome | 45.75 | 12.30 | 106 | 45516 | 22829 | 29506076 |
Cardiac ventricular thrombosis | 44.83 | 12.30 | 24 | 45598 | 915 | 29527990 |
Pulmonary haemorrhage | 44.75 | 12.30 | 63 | 45559 | 9207 | 29519698 |
Ventricular tachycardia | 44.66 | 12.30 | 104 | 45518 | 22470 | 29506435 |
Decreased appetite | 44.45 | 12.30 | 99 | 45523 | 145243 | 29383662 |
Insomnia | 44.22 | 12.30 | 43 | 45579 | 88718 | 29440187 |
Pulseless electrical activity | 44.07 | 12.30 | 52 | 45570 | 6382 | 29522523 |
Cerebral infarction | 42.75 | 12.30 | 108 | 45514 | 24567 | 29504338 |
Lymphocyte count decreased | 41.70 | 12.30 | 92 | 45530 | 19179 | 29509726 |
Product measured potency issue | 41.65 | 12.30 | 12 | 45610 | 78 | 29528827 |
Dizziness | 41.27 | 12.30 | 152 | 45470 | 189532 | 29339373 |
Skin necrosis | 40.26 | 12.30 | 44 | 45578 | 4968 | 29523937 |
Incision site pain | 39.73 | 12.30 | 28 | 45594 | 1755 | 29527150 |
Pain | 39.54 | 12.30 | 134 | 45488 | 171298 | 29357607 |
Kounis syndrome | 39.09 | 12.30 | 28 | 45594 | 1801 | 29527104 |
Coronary artery thrombosis | 39.01 | 12.30 | 29 | 45593 | 1976 | 29526929 |
Hypertransaminasaemia | 38.68 | 12.30 | 37 | 45585 | 3569 | 29525336 |
Weight increased | 38.35 | 12.30 | 37 | 45585 | 76630 | 29452275 |
Product dose omission issue | 38.09 | 12.30 | 56 | 45566 | 96327 | 29432578 |
Hereditary angioedema | 37.89 | 12.30 | 20 | 45602 | 741 | 29528164 |
Peripheral artery thrombosis | 37.54 | 12.30 | 29 | 45593 | 2093 | 29526812 |
Malaise | 37.32 | 12.30 | 124 | 45498 | 159478 | 29369427 |
Choroidal infarction | 36.76 | 12.30 | 11 | 45611 | 83 | 29528822 |
Suspected product quality issue | 36.18 | 12.30 | 12 | 45610 | 131 | 29528774 |
Adrenal haemorrhage | 36.01 | 12.30 | 13 | 45609 | 186 | 29528719 |
Coagulopathy | 35.97 | 12.30 | 83 | 45539 | 17824 | 29511081 |
Psoriasis | 35.66 | 12.30 | 4 | 45618 | 32223 | 29496682 |
Therapeutic product effect decreased | 35.45 | 12.30 | 113 | 45509 | 29338 | 29499567 |
Muscle spasms | 35.44 | 12.30 | 29 | 45593 | 65053 | 29463852 |
Product quality issue | 34.52 | 12.30 | 76 | 45546 | 15819 | 29513086 |
Respiratory failure | 34.38 | 12.30 | 262 | 45360 | 96869 | 29432036 |
Musculoskeletal stiffness | 33.99 | 12.30 | 8 | 45614 | 37450 | 29491455 |
Aggression | 33.44 | 12.30 | 7 | 45615 | 35534 | 29493371 |
Cerebral venous sinus thrombosis | 33.41 | 12.30 | 15 | 45607 | 387 | 29528518 |
Pulmonary alveolar haemorrhage | 33.26 | 12.30 | 45 | 45577 | 6335 | 29522570 |
Intestinal ischaemia | 33.07 | 12.30 | 46 | 45576 | 6646 | 29522259 |
Gait disturbance | 32.67 | 12.30 | 39 | 45583 | 73310 | 29455595 |
Haemorrhagic infarction | 32.44 | 12.30 | 15 | 45607 | 415 | 29528490 |
Pulmonary haematoma | 32.44 | 12.30 | 9 | 45613 | 50 | 29528855 |
Myalgia | 32.29 | 12.30 | 40 | 45582 | 73979 | 29454926 |
Red blood cells urine positive | 32.11 | 12.30 | 24 | 45598 | 1649 | 29527256 |
Haematuria | 32.01 | 12.30 | 144 | 45478 | 43995 | 29484910 |
Puncture site haemorrhage | 31.65 | 12.30 | 13 | 45609 | 268 | 29528637 |
Intracardiac thrombus | 31.40 | 12.30 | 27 | 45595 | 2268 | 29526637 |
Aortic thrombosis | 31.38 | 12.30 | 17 | 45605 | 664 | 29528241 |
Asthma | 31.17 | 12.30 | 7 | 45615 | 33842 | 29495063 |
Vascular stent occlusion | 31.08 | 12.30 | 11 | 45611 | 148 | 29528757 |
Memory impairment | 30.79 | 12.30 | 9 | 45613 | 36461 | 29492444 |
Heparin-induced thrombocytopenia test | 30.58 | 12.30 | 10 | 45612 | 104 | 29528801 |
Dehydration | 30.49 | 12.30 | 84 | 45538 | 114664 | 29414241 |
Atrial thrombosis | 30.47 | 12.30 | 25 | 45597 | 1968 | 29526937 |
Burkholderia test positive | 30.27 | 12.30 | 19 | 45603 | 980 | 29527925 |
Renal infarct | 30.12 | 12.30 | 20 | 45602 | 1137 | 29527768 |
Arterial haemorrhage | 29.97 | 12.30 | 17 | 45605 | 727 | 29528178 |
Vasodilatation | 29.84 | 12.30 | 19 | 45603 | 1005 | 29527900 |
Cerebral reperfusion injury | 29.80 | 12.30 | 6 | 45616 | 4 | 29528901 |
Stress | 29.16 | 12.30 | 86 | 45536 | 21404 | 29507501 |
Embolism | 29.12 | 12.30 | 44 | 45578 | 6852 | 29522053 |
Reperfusion injury | 29.09 | 12.30 | 9 | 45613 | 77 | 29528828 |
Cerebral hyperperfusion syndrome | 28.99 | 12.30 | 9 | 45613 | 78 | 29528827 |
Balance disorder | 28.63 | 12.30 | 10 | 45612 | 36160 | 29492745 |
Brain oedema | 28.34 | 12.30 | 60 | 45562 | 12160 | 29516745 |
Drug intolerance | 28.33 | 12.30 | 20 | 45602 | 48359 | 29480546 |
Coronary artery perforation | 28.04 | 12.30 | 8 | 45614 | 50 | 29528855 |
Chest wall haematoma | 27.70 | 12.30 | 10 | 45612 | 143 | 29528762 |
Cardiac procedure complication | 27.33 | 12.30 | 10 | 45612 | 149 | 29528756 |
Product contamination | 27.27 | 12.30 | 15 | 45607 | 604 | 29528301 |
Electrocardiogram ST segment elevation | 27.02 | 12.30 | 34 | 45588 | 4458 | 29524447 |
Device related thrombosis | 26.50 | 12.30 | 17 | 45605 | 911 | 29527994 |
Tongue haematoma | 26.07 | 12.30 | 9 | 45613 | 112 | 29528793 |
Peripheral artery occlusion | 25.91 | 12.30 | 20 | 45602 | 1442 | 29527463 |
Anticoagulation drug level below therapeutic | 25.85 | 12.30 | 15 | 45607 | 670 | 29528235 |
Spinal epidural haematoma | 25.83 | 12.30 | 11 | 45611 | 249 | 29528656 |
Haemorrhagic transformation stroke | 25.65 | 12.30 | 19 | 45603 | 1287 | 29527618 |
Neuropathy peripheral | 25.47 | 12.30 | 44 | 45578 | 70983 | 29457922 |
Blood urea increased | 25.30 | 12.30 | 98 | 45524 | 28014 | 29500891 |
Prosthetic cardiac valve thrombosis | 25.08 | 12.30 | 6 | 45616 | 16 | 29528889 |
Ischaemic hepatitis | 24.90 | 12.30 | 20 | 45602 | 1528 | 29527377 |
Aneurysm ruptured | 24.89 | 12.30 | 13 | 45609 | 471 | 29528434 |
Somnolence | 24.79 | 12.30 | 69 | 45553 | 93886 | 29435019 |
Aortic dissection | 24.70 | 12.30 | 24 | 45598 | 2360 | 29526545 |
Acute myocardial infarction | 24.59 | 12.30 | 143 | 45479 | 48295 | 29480610 |
Acute respiratory failure | 24.55 | 12.30 | 93 | 45529 | 26309 | 29502596 |
Haemoperitoneum | 24.52 | 12.30 | 20 | 45602 | 1562 | 29527343 |
Jugular vein thrombosis | 24.48 | 12.30 | 19 | 45603 | 1381 | 29527524 |
Injection site pain | 23.96 | 12.30 | 10 | 45612 | 32436 | 29496469 |
Leukocytosis | 23.53 | 12.30 | 79 | 45543 | 21063 | 29507842 |
Agitation | 23.14 | 12.30 | 27 | 45595 | 51277 | 29477628 |
Arthropathy | 23.04 | 12.30 | 3 | 45619 | 21551 | 29507354 |
Gastrointestinal haemorrhage | 23.00 | 12.30 | 205 | 45417 | 79328 | 29449577 |
Subdural haematoma | 22.99 | 12.30 | 71 | 45551 | 18122 | 29510783 |
Abdominal discomfort | 22.93 | 12.30 | 24 | 45598 | 47879 | 29481026 |
Vascular pseudoaneurysm | 22.83 | 12.30 | 21 | 45601 | 1928 | 29526977 |
Embolic stroke | 22.82 | 12.30 | 28 | 45594 | 3578 | 29525327 |
Vena cava thrombosis | 22.71 | 12.30 | 16 | 45606 | 1002 | 29527903 |
Cerebral mass effect | 22.38 | 12.30 | 15 | 45607 | 866 | 29528039 |
Pain in extremity | 22.37 | 12.30 | 91 | 45531 | 110342 | 29418563 |
Acute right ventricular failure | 22.25 | 12.30 | 8 | 45614 | 113 | 29528792 |
Haemorrhagic cerebral infarction | 22.19 | 12.30 | 14 | 45608 | 729 | 29528176 |
Feeling abnormal | 22.12 | 12.30 | 31 | 45591 | 54414 | 29474491 |
Rash morbilliform | 21.99 | 12.30 | 23 | 45599 | 2470 | 29526435 |
Suspected transmission of an infectious agent via product | 21.82 | 12.30 | 13 | 45609 | 610 | 29528295 |
Hypercoagulation | 21.70 | 12.30 | 16 | 45606 | 1076 | 29527829 |
Gastrointestinal necrosis | 21.65 | 12.30 | 25 | 45597 | 2997 | 29525908 |
Dyspnoea exertional | 21.47 | 12.30 | 15 | 45607 | 36475 | 29492430 |
Haemorrhagic stroke | 21.45 | 12.30 | 35 | 45587 | 5821 | 29523084 |
Rash | 21.19 | 12.30 | 189 | 45433 | 189630 | 29339275 |
Antiphospholipid syndrome | 20.95 | 12.30 | 11 | 45611 | 403 | 29528502 |
Peripheral ischaemia | 20.68 | 12.30 | 32 | 45590 | 5087 | 29523818 |
Incorrect drug administration rate | 20.65 | 12.30 | 16 | 45606 | 1160 | 29527745 |
Activated partial thromboplastin time shortened | 20.53 | 12.30 | 11 | 45611 | 420 | 29528485 |
Dyspnoea | 20.48 | 12.30 | 368 | 45254 | 326364 | 29202541 |
Foetal growth restriction | 20.30 | 12.30 | 27 | 45595 | 3739 | 29525166 |
Dysgeusia | 20.26 | 12.30 | 5 | 45617 | 22669 | 29506236 |
Foetal exposure timing unspecified | 20.23 | 12.30 | 9 | 45613 | 227 | 29528678 |
Loss of personal independence in daily activities | 20.19 | 12.30 | 7 | 45615 | 25433 | 29503472 |
Drug hypersensitivity | 20.13 | 12.30 | 177 | 45445 | 68229 | 29460676 |
Mixed liver injury | 20.05 | 12.30 | 20 | 45602 | 2031 | 29526874 |
Overdose | 20.04 | 12.30 | 60 | 45562 | 79759 | 29449146 |
Neutrophil count increased | 20.00 | 12.30 | 59 | 45563 | 14683 | 29514222 |
Peripheral swelling | 19.79 | 12.30 | 43 | 45579 | 63696 | 29465209 |
Unresponsive to stimuli | 19.75 | 12.30 | 84 | 45538 | 25042 | 29503863 |
Livedo reticularis | 19.75 | 12.30 | 20 | 45602 | 2068 | 29526837 |
Hemiplegia | 19.68 | 12.30 | 36 | 45586 | 6558 | 29522347 |
Respiratory tract oedema | 19.68 | 12.30 | 10 | 45612 | 342 | 29528563 |
Arthritis | 19.66 | 12.30 | 7 | 45615 | 25012 | 29503893 |
Alopecia | 19.60 | 12.30 | 3 | 45619 | 19081 | 29509824 |
Herpes zoster | 19.55 | 12.30 | 11 | 45611 | 30041 | 29498864 |
Toxic epidermal necrolysis | 19.47 | 12.30 | 67 | 45555 | 18086 | 29510819 |
Anxiety | 19.46 | 12.30 | 67 | 45555 | 85298 | 29443607 |
Oedema peripheral | 19.33 | 12.30 | 88 | 45534 | 103469 | 29425436 |
Peliosis hepatis | 19.32 | 12.30 | 6 | 45616 | 52 | 29528853 |
Extradural haematoma | 19.32 | 12.30 | 15 | 45607 | 1091 | 29527814 |
Graft thrombosis | 19.24 | 12.30 | 9 | 45613 | 256 | 29528649 |
Psychotic disorder | 19.17 | 12.30 | 4 | 45618 | 20350 | 29508555 |
Mediastinal haematoma | 19.15 | 12.30 | 7 | 45615 | 104 | 29528801 |
Epistaxis | 19.14 | 12.30 | 141 | 45481 | 51563 | 29477342 |
Sleep disorder | 18.86 | 12.30 | 7 | 45615 | 24379 | 29504526 |
Intrapericardial thrombosis | 18.84 | 12.30 | 6 | 45616 | 57 | 29528848 |
Shock | 18.76 | 12.30 | 74 | 45548 | 21330 | 29507575 |
Nasopharyngitis | 18.74 | 12.30 | 40 | 45582 | 59625 | 29469280 |
Vascular access site haematoma | 18.67 | 12.30 | 4 | 45618 | 5 | 29528900 |
Medical device site thrombosis | 18.30 | 12.30 | 5 | 45617 | 26 | 29528879 |
Bronchial haemorrhage | 18.25 | 12.30 | 12 | 45610 | 671 | 29528234 |
Osteoarthritis | 18.24 | 12.30 | 3 | 45619 | 18100 | 29510805 |
Anticoagulation drug level above therapeutic | 18.16 | 12.30 | 18 | 45604 | 1813 | 29527092 |
Haemoptysis | 18.05 | 12.30 | 94 | 45528 | 30456 | 29498449 |
Ischaemic stroke | 18.04 | 12.30 | 60 | 45562 | 15917 | 29512988 |
Hypoxia | 17.99 | 12.30 | 130 | 45492 | 47249 | 29481656 |
Cognitive disorder | 17.75 | 12.30 | 7 | 45615 | 23492 | 29505413 |
Gastric haemorrhage | 17.48 | 12.30 | 42 | 45580 | 9255 | 29519650 |
Subcutaneous haematoma | 17.42 | 12.30 | 13 | 45609 | 891 | 29528014 |
Therapeutic product ineffective | 17.39 | 12.30 | 11 | 45611 | 575 | 29528330 |
Vertigo | 17.37 | 12.30 | 6 | 45616 | 21855 | 29507050 |
Diabetes insipidus | 17.21 | 12.30 | 20 | 45602 | 2414 | 29526491 |
Thrombotic microangiopathy | 17.17 | 12.30 | 40 | 45582 | 8641 | 29520264 |
Pancreatic haemorrhage | 17.16 | 12.30 | 5 | 45617 | 34 | 29528871 |
Protein urine present | 17.11 | 12.30 | 28 | 45594 | 4666 | 29524239 |
Prostate cancer | 17.10 | 12.30 | 9 | 45613 | 25518 | 29503387 |
Pulmonary artery thrombosis | 16.91 | 12.30 | 11 | 45611 | 604 | 29528301 |
Abdominal distension | 16.87 | 12.30 | 125 | 45497 | 45786 | 29483119 |
Malignant neoplasm progression | 16.81 | 12.30 | 58 | 45564 | 73801 | 29455104 |
Mean cell haemoglobin concentration | 16.80 | 12.30 | 5 | 45617 | 37 | 29528868 |
Platelet disorder | 16.65 | 12.30 | 15 | 45607 | 1340 | 29527565 |
Vascular access site haemorrhage | 16.63 | 12.30 | 4 | 45618 | 11 | 29528894 |
Visual impairment | 16.46 | 12.30 | 13 | 45609 | 29695 | 29499210 |
Anisochromia | 16.43 | 12.30 | 3 | 45619 | 0 | 29528905 |
Acquired antithrombin III deficiency | 16.43 | 12.30 | 3 | 45619 | 0 | 29528905 |
Procedural pain | 16.41 | 12.30 | 26 | 45596 | 4218 | 29524687 |
Ventricular asystole | 16.33 | 12.30 | 7 | 45615 | 161 | 29528744 |
Irritability | 16.08 | 12.30 | 7 | 45615 | 22145 | 29506760 |
Dermatitis bullous | 16.08 | 12.30 | 31 | 45591 | 5875 | 29523030 |
Blood loss anaemia | 16.07 | 12.30 | 35 | 45587 | 7231 | 29521674 |
Cough | 16.03 | 12.30 | 122 | 45500 | 126605 | 29402300 |
Blood pressure decreased | 15.69 | 12.30 | 122 | 45500 | 45355 | 29483550 |
Neonatal respiratory distress syndrome | 15.65 | 12.30 | 24 | 45598 | 3786 | 29525119 |
Treatment noncompliance | 15.57 | 12.30 | 9 | 45613 | 24218 | 29504687 |
Urea renal clearance decreased | 15.49 | 12.30 | 4 | 45618 | 16 | 29528889 |
Head injury | 15.47 | 12.30 | 3 | 45619 | 16078 | 29512827 |
Hypovolaemic shock | 15.47 | 12.30 | 31 | 45591 | 6041 | 29522864 |
Renal haemorrhage | 15.44 | 12.30 | 14 | 45608 | 1262 | 29527643 |
Nutritional condition abnormal | 15.33 | 12.30 | 9 | 45613 | 411 | 29528494 |
Tachycardia | 15.31 | 12.30 | 175 | 45447 | 72235 | 29456670 |
Rhinorrhoea | 15.31 | 12.30 | 7 | 45615 | 21512 | 29507393 |
Confusional state | 15.29 | 12.30 | 125 | 45497 | 127752 | 29401153 |
Gangrene | 15.16 | 12.30 | 25 | 45597 | 4193 | 29524712 |
Melaena | 15.15 | 12.30 | 91 | 45531 | 31085 | 29497820 |
Respiratory distress | 15.15 | 12.30 | 93 | 45529 | 32013 | 29496892 |
Ventricular extrasystoles | 14.98 | 12.30 | 43 | 45579 | 10539 | 29518366 |
Hepatic infarction | 14.96 | 12.30 | 7 | 45615 | 199 | 29528706 |
Cerebral haematoma | 14.82 | 12.30 | 25 | 45597 | 4271 | 29524634 |
COVID-19 pneumonia | 14.77 | 12.30 | 40 | 45582 | 9482 | 29519423 |
Alveolitis necrotising | 14.77 | 12.30 | 4 | 45618 | 20 | 29528885 |
Retinal pigment epitheliopathy | 14.71 | 12.30 | 7 | 45615 | 207 | 29528698 |
Basal cell carcinoma | 14.59 | 12.30 | 4 | 45618 | 16906 | 29511999 |
Splenic infarction | 14.52 | 12.30 | 16 | 45606 | 1823 | 29527082 |
Bronchopulmonary aspergillosis | 14.52 | 12.30 | 47 | 45575 | 12297 | 29516608 |
Myiasis | 14.45 | 12.30 | 4 | 45618 | 22 | 29528883 |
Reperfusion arrhythmia | 14.36 | 12.30 | 5 | 45617 | 64 | 29528841 |
Autoimmune heparin-induced thrombocytopenia | 14.35 | 12.30 | 3 | 45619 | 3 | 29528902 |
Bullous haemorrhagic dermatosis | 14.35 | 12.30 | 3 | 45619 | 3 | 29528902 |
Intra-abdominal haematoma | 14.34 | 12.30 | 13 | 45609 | 1171 | 29527734 |
Distributive shock | 14.32 | 12.30 | 12 | 45610 | 973 | 29527932 |
Vision blurred | 14.29 | 12.30 | 25 | 45597 | 40151 | 29488754 |
Fungal sepsis | 14.19 | 12.30 | 11 | 45611 | 798 | 29528107 |
Haemorrhagic cholecystitis | 14.08 | 12.30 | 5 | 45617 | 68 | 29528837 |
Upper gastrointestinal haemorrhage | 14.05 | 12.30 | 69 | 45553 | 21845 | 29507060 |
Monoplegia | 13.97 | 12.30 | 14 | 45608 | 1429 | 29527476 |
Hot flush | 13.84 | 12.30 | 3 | 45619 | 14867 | 29514038 |
Gastrooesophageal reflux disease | 13.75 | 12.30 | 17 | 45605 | 31479 | 29497426 |
Wrong technique in product usage process | 13.68 | 12.30 | 17 | 45605 | 31411 | 29497494 |
Microangiopathic haemolytic anaemia | 13.65 | 12.30 | 11 | 45611 | 844 | 29528061 |
Complications of transplanted kidney | 13.63 | 12.30 | 23 | 45599 | 3931 | 29524974 |
Inferior vena caval occlusion | 13.63 | 12.30 | 4 | 45618 | 28 | 29528877 |
Necrotising oesophagitis | 13.53 | 12.30 | 9 | 45613 | 513 | 29528392 |
Coronary artery aneurysm | 13.45 | 12.30 | 5 | 45617 | 78 | 29528827 |
Encephalopathy | 13.45 | 12.30 | 88 | 45534 | 30955 | 29497950 |
Tremor | 13.42 | 12.30 | 63 | 45559 | 73475 | 29455430 |
Full blood count decreased | 13.40 | 12.30 | 4 | 45618 | 15988 | 29512917 |
Primary adrenal insufficiency | 13.39 | 12.30 | 4 | 45618 | 30 | 29528875 |
Apgar score abnormal | 13.39 | 12.30 | 4 | 45618 | 30 | 29528875 |
Blood pressure fluctuation | 13.35 | 12.30 | 7 | 45615 | 19887 | 29509018 |
Catheter site haematoma | 13.32 | 12.30 | 6 | 45616 | 156 | 29528749 |
Influenza | 13.21 | 12.30 | 28 | 45594 | 41853 | 29487052 |
Vascular graft thrombosis | 13.18 | 12.30 | 6 | 45616 | 160 | 29528745 |
Microstomia | 13.14 | 12.30 | 3 | 45619 | 6 | 29528899 |
Paraesthesia | 13.14 | 12.30 | 41 | 45581 | 53804 | 29475101 |
Aplastic anaemia | 13.13 | 12.30 | 33 | 45589 | 7477 | 29521428 |
Basophil count decreased | 13.06 | 12.30 | 5 | 45617 | 85 | 29528820 |
Platelet transfusion | 13.04 | 12.30 | 12 | 45610 | 1102 | 29527803 |
Syncope | 12.99 | 12.30 | 73 | 45549 | 81298 | 29447607 |
Soft tissue necrosis | 12.93 | 12.30 | 7 | 45615 | 273 | 29528632 |
Cytokine release syndrome | 12.85 | 12.30 | 47 | 45575 | 13072 | 29515833 |
Road traffic accident | 12.84 | 12.30 | 4 | 45618 | 15557 | 29513348 |
Disease progression | 12.80 | 12.30 | 74 | 45548 | 81842 | 29447063 |
White blood cell count decreased | 12.65 | 12.30 | 76 | 45546 | 83286 | 29445619 |
Hemiparesis | 12.62 | 12.30 | 50 | 45572 | 14436 | 29514469 |
Renal artery thrombosis | 12.59 | 12.30 | 7 | 45615 | 288 | 29528617 |
Lumbar puncture | 12.55 | 12.30 | 5 | 45617 | 95 | 29528810 |
Incision site haematoma | 12.55 | 12.30 | 5 | 45617 | 95 | 29528810 |
Anti factor Xa activity decreased | 12.54 | 12.30 | 3 | 45619 | 8 | 29528897 |
Torsade de pointes | 12.42 | 12.30 | 30 | 45592 | 6631 | 29522274 |
Orthostatic hypotension | 12.41 | 12.30 | 10 | 45612 | 22619 | 29506286 |
Hallucination | 12.41 | 12.30 | 32 | 45590 | 44680 | 29484225 |
Respiratory gas exchange disorder | 12.40 | 12.30 | 8 | 45614 | 433 | 29528472 |
Alanine aminotransferase decreased | 12.36 | 12.30 | 10 | 45612 | 772 | 29528133 |
Osteonecrosis of jaw | 12.33 | 12.30 | 5 | 45617 | 16505 | 29512400 |
Haemobilia | 12.31 | 12.30 | 7 | 45615 | 301 | 29528604 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Heparin-induced thrombocytopenia | 5007.80 | 10.96 | 1308 | 79562 | 7171 | 64410691 |
Vascular stent thrombosis | 507.59 | 10.96 | 182 | 80688 | 3182 | 64414680 |
Thrombocytopenia | 462.77 | 10.96 | 926 | 79944 | 222875 | 64194987 |
Labelled drug-drug interaction medication error | 382.34 | 10.96 | 274 | 80596 | 21788 | 64396074 |
Haemorrhage | 352.33 | 10.96 | 465 | 80405 | 78886 | 64338976 |
Shock haemorrhagic | 348.46 | 10.96 | 233 | 80637 | 16558 | 64401304 |
Haematoma | 318.07 | 10.96 | 339 | 80531 | 45911 | 64371951 |
Cerebral haemorrhage | 267.29 | 10.96 | 325 | 80545 | 50765 | 64367097 |
Retroperitoneal haematoma | 262.52 | 10.96 | 125 | 80745 | 4586 | 64413276 |
Completed suicide | 252.76 | 10.96 | 6 | 80864 | 224408 | 64193454 |
Cardiogenic shock | 252.30 | 10.96 | 254 | 80616 | 32173 | 64385689 |
Haemorrhage intracranial | 250.90 | 10.96 | 221 | 80649 | 23663 | 64394199 |
Thrombosis | 240.91 | 10.96 | 365 | 80505 | 70277 | 64347585 |
Pulmonary embolism | 240.27 | 10.96 | 552 | 80318 | 145804 | 64272058 |
Premature delivery | 236.36 | 10.96 | 192 | 80678 | 18397 | 64399465 |
Multiple organ dysfunction syndrome | 235.21 | 10.96 | 441 | 80429 | 100972 | 64316890 |
Thrombosis in device | 218.60 | 10.96 | 113 | 80757 | 4958 | 64412904 |
Retroperitoneal haemorrhage | 217.14 | 10.96 | 111 | 80759 | 4757 | 64413105 |
Arthralgia | 216.06 | 10.96 | 145 | 80725 | 442115 | 63975747 |
Fatigue | 188.37 | 10.96 | 413 | 80457 | 748317 | 63669545 |
Joint swelling | 188.33 | 10.96 | 24 | 80846 | 215358 | 64202504 |
Rheumatoid arthritis | 179.03 | 10.96 | 6 | 80864 | 164288 | 64253574 |
Activated partial thromboplastin time prolonged | 174.77 | 10.96 | 138 | 80732 | 12693 | 64405169 |
Pain | 171.18 | 10.96 | 269 | 80601 | 553242 | 63864620 |
Cardiac tamponade | 168.67 | 10.96 | 113 | 80757 | 8051 | 64409811 |
Post procedural haemorrhage | 167.82 | 10.96 | 133 | 80737 | 12298 | 64405564 |
Acute kidney injury | 166.79 | 10.96 | 1047 | 79823 | 448193 | 63969669 |
Drug intolerance | 146.21 | 10.96 | 29 | 80841 | 187963 | 64229899 |
Coagulation time shortened | 145.96 | 10.96 | 42 | 80828 | 344 | 64417518 |
Maternal exposure during pregnancy | 144.56 | 10.96 | 350 | 80520 | 95534 | 64322328 |
Cerebral infarction | 144.03 | 10.96 | 215 | 80655 | 40829 | 64377033 |
Haemothorax | 137.57 | 10.96 | 82 | 80788 | 4760 | 64413102 |
Cardiac arrest | 137.12 | 10.96 | 465 | 80405 | 153599 | 64264263 |
Sepsis | 137.05 | 10.96 | 612 | 80258 | 229729 | 64188133 |
Off label use | 132.45 | 10.96 | 1291 | 79579 | 631515 | 63786347 |
Appendicolith | 131.65 | 10.96 | 71 | 80799 | 3398 | 64414464 |
Haematoma muscle | 129.55 | 10.96 | 57 | 80813 | 1736 | 64416126 |
Brain herniation | 126.80 | 10.96 | 87 | 80783 | 6446 | 64411416 |
Ventricular fibrillation | 126.71 | 10.96 | 153 | 80717 | 23707 | 64394155 |
Septic shock | 126.20 | 10.96 | 353 | 80517 | 105084 | 64312778 |
Abdominal wall haematoma | 125.17 | 10.96 | 74 | 80796 | 4231 | 64413631 |
Heparin-induced thrombocytopenia test positive | 124.84 | 10.96 | 30 | 80840 | 108 | 64417754 |
Compartment syndrome | 123.71 | 10.96 | 73 | 80797 | 4159 | 64413703 |
Exposure during pregnancy | 122.96 | 10.96 | 289 | 80581 | 77386 | 64340476 |
Drug abuse | 122.60 | 10.96 | 12 | 80858 | 132362 | 64285500 |
Deep vein thrombosis | 120.87 | 10.96 | 347 | 80523 | 104835 | 64313027 |
Arthropathy | 120.26 | 10.96 | 8 | 80862 | 120959 | 64296903 |
Arterial thrombosis | 118.91 | 10.96 | 59 | 80811 | 2371 | 64415491 |
Subarachnoid haemorrhage | 117.69 | 10.96 | 130 | 80740 | 18308 | 64399554 |
Eosinophilia | 117.55 | 10.96 | 188 | 80682 | 37888 | 64379974 |
Haemoglobin decreased | 117.29 | 10.96 | 520 | 80350 | 194543 | 64223319 |
Heparin resistance | 116.34 | 10.96 | 23 | 80847 | 20 | 64417842 |
Product use in unapproved indication | 116.31 | 10.96 | 484 | 80386 | 176134 | 64241728 |
Alopecia | 116.08 | 10.96 | 32 | 80838 | 165658 | 64252204 |
Vascular pseudoaneurysm | 115.94 | 10.96 | 63 | 80807 | 3061 | 64414801 |
Toxicity to various agents | 114.72 | 10.96 | 174 | 80696 | 363339 | 64054523 |
Coagulation time prolonged | 113.67 | 10.96 | 55 | 80815 | 2091 | 64415771 |
Pharyngeal haemorrhage | 112.77 | 10.96 | 46 | 80824 | 1156 | 64416706 |
Disseminated intravascular coagulation | 111.42 | 10.96 | 168 | 80702 | 32180 | 64385682 |
Muscle haemorrhage | 105.52 | 10.96 | 74 | 80796 | 5679 | 64412183 |
Extradural haematoma | 105.00 | 10.96 | 56 | 80814 | 2620 | 64415242 |
Haemoperitoneum | 100.17 | 10.96 | 62 | 80808 | 3853 | 64414009 |
Respiratory failure | 98.61 | 10.96 | 432 | 80438 | 160751 | 64257111 |
Hereditary angioedema | 98.20 | 10.96 | 61 | 80809 | 3815 | 64414047 |
Spinal epidural haematoma | 97.95 | 10.96 | 42 | 80828 | 1200 | 64416662 |
Drug reaction with eosinophilia and systemic symptoms | 97.24 | 10.96 | 212 | 80658 | 54005 | 64363857 |
Procedural haemorrhage | 95.47 | 10.96 | 62 | 80808 | 4190 | 64413672 |
Venous thrombosis | 92.03 | 10.96 | 71 | 80799 | 6310 | 64411552 |
Hypotension | 91.39 | 10.96 | 801 | 80069 | 380173 | 64037689 |
Abdominal discomfort | 91.23 | 10.96 | 58 | 80812 | 182264 | 64235598 |
Nasopharyngitis | 89.37 | 10.96 | 69 | 80801 | 196004 | 64221858 |
Weight increased | 88.76 | 10.96 | 82 | 80788 | 213266 | 64204596 |
Malaise | 88.59 | 10.96 | 232 | 80638 | 396015 | 64021847 |
Rash maculo-papular | 87.90 | 10.96 | 187 | 80683 | 46839 | 64371023 |
Coronary artery thrombosis | 87.85 | 10.96 | 51 | 80819 | 2818 | 64415044 |
Intentional overdose | 86.39 | 10.96 | 7 | 80863 | 89937 | 64327925 |
Catheter site haemorrhage | 84.08 | 10.96 | 59 | 80811 | 4532 | 64413330 |
Choroidal infarction | 83.21 | 10.96 | 23 | 80847 | 160 | 64417702 |
Dizziness | 82.28 | 10.96 | 271 | 80599 | 429892 | 63987970 |
Intraventricular haemorrhage | 82.24 | 10.96 | 56 | 80814 | 4097 | 64413765 |
Intracardiac thrombus | 82.13 | 10.96 | 54 | 80816 | 3727 | 64414135 |
Appendicitis | 82.02 | 10.96 | 93 | 80777 | 13476 | 64404386 |
Product administration error | 81.93 | 10.96 | 134 | 80736 | 27509 | 64390353 |
Weight decreased | 80.59 | 10.96 | 147 | 80723 | 285592 | 64132270 |
Depression | 80.40 | 10.96 | 67 | 80803 | 183224 | 64234638 |
Pericardial haemorrhage | 80.08 | 10.96 | 55 | 80815 | 4081 | 64413781 |
Skin necrosis | 79.55 | 10.96 | 94 | 80776 | 14235 | 64403627 |
Fall | 78.07 | 10.96 | 265 | 80605 | 416561 | 64001301 |
Intra-abdominal haemorrhage | 76.62 | 10.96 | 53 | 80817 | 3978 | 64413884 |
Adrenal haemorrhage | 75.72 | 10.96 | 28 | 80842 | 536 | 64417326 |
Toxic epidermal necrolysis | 75.56 | 10.96 | 153 | 80717 | 37013 | 64380849 |
Coagulopathy | 75.39 | 10.96 | 140 | 80730 | 31780 | 64386082 |
Peripheral artery thrombosis | 75.25 | 10.96 | 47 | 80823 | 2968 | 64414894 |
Subdural haematoma | 75.17 | 10.96 | 130 | 80740 | 27924 | 64389938 |
Embolism | 74.20 | 10.96 | 84 | 80786 | 12151 | 64405711 |
Pulmonary alveolar haemorrhage | 73.38 | 10.96 | 75 | 80795 | 9663 | 64408199 |
Acute myocardial infarction | 71.50 | 10.96 | 221 | 80649 | 69497 | 64348365 |
Coagulation time | 71.18 | 10.96 | 13 | 80857 | 3 | 64417859 |
Musculoskeletal stiffness | 70.63 | 10.96 | 33 | 80837 | 123173 | 64294689 |
Aplastic anaemia | 70.24 | 10.96 | 87 | 80783 | 13833 | 64404029 |
Gait disturbance | 69.44 | 10.96 | 68 | 80802 | 172087 | 64245775 |
Injection site pain | 68.39 | 10.96 | 27 | 80843 | 111381 | 64306481 |
Peripheral ischaemia | 67.67 | 10.96 | 67 | 80803 | 8311 | 64409551 |
Diarrhoea | 67.13 | 10.96 | 582 | 80288 | 722122 | 63695740 |
Arthritis | 67.10 | 10.96 | 12 | 80858 | 83802 | 64334060 |
Haemodynamic instability | 67.04 | 10.96 | 88 | 80782 | 14824 | 64403038 |
Insomnia | 66.96 | 10.96 | 90 | 80780 | 197746 | 64220116 |
Pulseless electrical activity | 66.51 | 10.96 | 81 | 80789 | 12658 | 64405204 |
Psoriasis | 65.08 | 10.96 | 7 | 80863 | 71696 | 64346166 |
Acute respiratory distress syndrome | 65.03 | 10.96 | 148 | 80722 | 38787 | 64379075 |
Suicidal ideation | 64.40 | 10.96 | 5 | 80865 | 66537 | 64351325 |
Suicide attempt | 64.27 | 10.96 | 7 | 80863 | 71000 | 64346862 |
Gastrointestinal haemorrhage | 63.71 | 10.96 | 331 | 80539 | 131981 | 64285881 |
Pemphigus | 63.44 | 10.96 | 3 | 80867 | 60698 | 64357164 |
Haematuria | 63.23 | 10.96 | 193 | 80677 | 60278 | 64357584 |
Product dose omission issue | 61.55 | 10.96 | 93 | 80777 | 194654 | 64223208 |
Haemorrhagic transformation stroke | 61.54 | 10.96 | 38 | 80832 | 2351 | 64415511 |
Hypoxia | 61.46 | 10.96 | 246 | 80624 | 87903 | 64329959 |
Coagulation time abnormal | 61.11 | 10.96 | 19 | 80851 | 208 | 64417654 |
Aortic thrombosis | 60.30 | 10.96 | 32 | 80838 | 1482 | 64416380 |
Lower respiratory tract infection | 59.62 | 10.96 | 22 | 80848 | 94592 | 64323270 |
Cardiac ventricular thrombosis | 59.36 | 10.96 | 31 | 80839 | 1389 | 64416473 |
Asthenia | 59.10 | 10.96 | 306 | 80564 | 427738 | 63990124 |
Asthma | 58.57 | 10.96 | 23 | 80847 | 95202 | 64322660 |
Wound | 56.95 | 10.96 | 13 | 80857 | 76464 | 64341398 |
Ventricular tachycardia | 56.95 | 10.96 | 130 | 80740 | 34135 | 64383727 |
Peripheral swelling | 56.82 | 10.96 | 110 | 80760 | 209043 | 64208819 |
Haemorrhagic infarction | 56.12 | 10.96 | 24 | 80846 | 681 | 64417181 |
Pain in extremity | 55.12 | 10.96 | 195 | 80675 | 302890 | 64114972 |
Product measured potency issue | 54.68 | 10.96 | 17 | 80853 | 186 | 64417676 |
Rash | 54.59 | 10.96 | 344 | 80526 | 458205 | 63959657 |
Encephalopathy | 54.43 | 10.96 | 180 | 80690 | 58639 | 64359223 |
Systemic lupus erythematosus | 54.31 | 10.96 | 15 | 80855 | 77597 | 64340265 |
Vasodilatation | 53.45 | 10.96 | 38 | 80832 | 2980 | 64414882 |
Headache | 52.41 | 10.96 | 419 | 80451 | 529048 | 63888814 |
Memory impairment | 52.20 | 10.96 | 21 | 80849 | 85661 | 64332201 |
Cerebral haematoma | 51.72 | 10.96 | 54 | 80816 | 7131 | 64410731 |
Arterial haemorrhage | 51.24 | 10.96 | 33 | 80837 | 2198 | 64415664 |
Puncture site haemorrhage | 51.14 | 10.96 | 21 | 80849 | 537 | 64417325 |
Blood pressure decreased | 51.12 | 10.96 | 229 | 80641 | 85970 | 64331892 |
Pulmonary haemorrhage | 50.81 | 10.96 | 72 | 80798 | 13037 | 64404825 |
Vena cava thrombosis | 50.04 | 10.96 | 34 | 80836 | 2478 | 64415384 |
Myalgia | 49.86 | 10.96 | 76 | 80794 | 158541 | 64259321 |
Feeling abnormal | 49.14 | 10.96 | 57 | 80813 | 133545 | 64284317 |
Coronary artery perforation | 48.97 | 10.96 | 13 | 80857 | 76 | 64417786 |
Renal infarct | 48.91 | 10.96 | 33 | 80837 | 2378 | 64415484 |
Hypercoagulation | 48.71 | 10.96 | 34 | 80836 | 2589 | 64415273 |
Atrial thrombosis | 48.63 | 10.96 | 36 | 80834 | 3006 | 64414856 |
Thrombotic microangiopathy | 48.35 | 10.96 | 80 | 80790 | 16575 | 64401287 |
Incision site pain | 48.35 | 10.96 | 34 | 80836 | 2620 | 64415242 |
Mobility decreased | 47.66 | 10.96 | 24 | 80846 | 85816 | 64332046 |
Cerebral reperfusion injury | 47.29 | 10.96 | 10 | 80860 | 16 | 64417846 |
Gangrene | 47.28 | 10.96 | 52 | 80818 | 7286 | 64410576 |
Ischaemic stroke | 46.97 | 10.96 | 109 | 80761 | 28926 | 64388936 |
Shock | 46.66 | 10.96 | 129 | 80741 | 38111 | 64379751 |
Decreased appetite | 46.58 | 10.96 | 188 | 80682 | 281101 | 64136761 |
Electrocardiogram ST segment elevation | 46.01 | 10.96 | 51 | 80819 | 7208 | 64410654 |
Subchorionic haematoma | 45.89 | 10.96 | 13 | 80857 | 100 | 64417762 |
Suspected product quality issue | 45.80 | 10.96 | 16 | 80854 | 258 | 64417604 |
Intestinal ischaemia | 45.61 | 10.96 | 64 | 80806 | 11485 | 64406377 |
Acute respiratory failure | 45.48 | 10.96 | 152 | 80718 | 49782 | 64368080 |
Loss of personal independence in daily activities | 45.39 | 10.96 | 17 | 80853 | 72437 | 64345425 |
Osteoarthritis | 44.76 | 10.96 | 12 | 80858 | 63324 | 64354538 |
Mixed liver injury | 44.58 | 10.96 | 44 | 80826 | 5437 | 64412425 |
Anaemia | 43.77 | 10.96 | 692 | 80178 | 377988 | 64039874 |
Product contamination | 43.72 | 10.96 | 23 | 80847 | 1046 | 64416816 |
Respiratory distress | 43.05 | 10.96 | 154 | 80716 | 52177 | 64365685 |
Lymphocyte count decreased | 42.64 | 10.96 | 130 | 80740 | 40569 | 64377293 |
Heparin-induced thrombocytopenia test | 42.17 | 10.96 | 13 | 80857 | 138 | 64417724 |
Muscle spasms | 42.03 | 10.96 | 70 | 80800 | 140953 | 64276909 |
Infective aneurysm | 42.02 | 10.96 | 21 | 80849 | 857 | 64417005 |
Anticoagulation drug level below therapeutic | 41.98 | 10.96 | 24 | 80846 | 1288 | 64416574 |
Anxiety | 41.96 | 10.96 | 123 | 80747 | 202526 | 64215336 |
Foetal death | 41.67 | 10.96 | 44 | 80826 | 5886 | 64411976 |
Suspected transmission of an infectious agent via product | 41.11 | 10.96 | 21 | 80849 | 898 | 64416964 |
Death | 41.10 | 10.96 | 397 | 80473 | 482308 | 63935554 |
Peripheral artery occlusion | 40.38 | 10.96 | 28 | 80842 | 2110 | 64415752 |
Pulmonary infarction | 40.36 | 10.96 | 33 | 80837 | 3189 | 64414673 |
Antiphospholipid syndrome | 40.34 | 10.96 | 25 | 80845 | 1557 | 64416305 |
Blood pressure fluctuation | 40.29 | 10.96 | 8 | 80862 | 51863 | 64365999 |
Somnolence | 39.74 | 10.96 | 127 | 80743 | 203518 | 64214344 |
Orbital compartment syndrome | 39.48 | 10.96 | 9 | 80861 | 24 | 64417838 |
Acute motor-sensory axonal neuropathy | 39.45 | 10.96 | 16 | 80854 | 396 | 64417466 |
Splenic rupture | 39.44 | 10.96 | 28 | 80842 | 2191 | 64415671 |
Balance disorder | 38.89 | 10.96 | 29 | 80841 | 83897 | 64333965 |
Swelling | 38.70 | 10.96 | 90 | 80780 | 160128 | 64257734 |
Haemoptysis | 38.37 | 10.96 | 142 | 80728 | 48906 | 64368956 |
Vascular stent occlusion | 38.20 | 10.96 | 13 | 80857 | 193 | 64417669 |
Impaired healing | 38.20 | 10.96 | 14 | 80856 | 60459 | 64357403 |
Anti factor Xa activity decreased | 38.15 | 10.96 | 8 | 80862 | 12 | 64417850 |
Blood urea increased | 38.10 | 10.96 | 132 | 80738 | 44021 | 64373841 |
Injection site swelling | 37.62 | 10.96 | 4 | 80866 | 41349 | 64376513 |
Product quality issue | 36.83 | 10.96 | 101 | 80769 | 29698 | 64388164 |
Intra-abdominal haematoma | 36.66 | 10.96 | 28 | 80842 | 2451 | 64415411 |
Hemiplegia | 36.62 | 10.96 | 61 | 80809 | 12707 | 64405155 |
Rhinorrhoea | 36.03 | 10.96 | 15 | 80855 | 59954 | 64357908 |
Platelet count decreased | 35.22 | 10.96 | 343 | 80527 | 167368 | 64250494 |
Gastrointestinal necrosis | 35.01 | 10.96 | 37 | 80833 | 4955 | 64412907 |
Red blood cells urine positive | 34.67 | 10.96 | 35 | 80835 | 4443 | 64413419 |
Hypersensitivity | 34.62 | 10.96 | 128 | 80742 | 196324 | 64221538 |
Gastrooesophageal reflux disease | 34.49 | 10.96 | 32 | 80838 | 83111 | 64334751 |
Haemorrhagic cerebral infarction | 34.10 | 10.96 | 21 | 80849 | 1293 | 64416569 |
Pericarditis | 33.92 | 10.96 | 18 | 80852 | 62498 | 64355364 |
Splenic infarction | 33.91 | 10.96 | 30 | 80840 | 3227 | 64414635 |
Platelet aggregation inhibition | 33.87 | 10.96 | 11 | 80859 | 140 | 64417722 |
Hemiparesis | 33.83 | 10.96 | 98 | 80772 | 29729 | 64388133 |
Tachypnoea | 33.78 | 10.96 | 91 | 80779 | 26480 | 64391382 |
Spinal subdural haematoma | 33.60 | 10.96 | 12 | 80858 | 207 | 64417655 |
Injection site erythema | 33.41 | 10.96 | 24 | 80846 | 70776 | 64347086 |
Haemorrhagic stroke | 33.29 | 10.96 | 51 | 80819 | 9900 | 64407962 |
Oesophageal intramural haematoma | 32.80 | 10.96 | 10 | 80860 | 102 | 64417760 |
Blood creatinine increased | 32.69 | 10.96 | 286 | 80584 | 135496 | 64282366 |
Hypervolaemia | 32.63 | 10.96 | 114 | 80756 | 38171 | 64379691 |
Brain oedema | 32.61 | 10.96 | 80 | 80790 | 21995 | 64395867 |
Discomfort | 32.53 | 10.96 | 32 | 80838 | 80846 | 64337016 |
Cardiac procedure complication | 32.42 | 10.96 | 13 | 80857 | 312 | 64417550 |
Cerebral hyperperfusion syndrome | 32.28 | 10.96 | 10 | 80860 | 108 | 64417754 |
Ischaemic hepatitis | 32.02 | 10.96 | 29 | 80841 | 3217 | 64414645 |
Medical device site thrombosis | 31.87 | 10.96 | 8 | 80862 | 36 | 64417826 |
Ill-defined disorder | 31.79 | 10.96 | 8 | 80862 | 44044 | 64373818 |
Jugular vein thrombosis | 31.61 | 10.96 | 31 | 80839 | 3800 | 64414062 |
Anticoagulation drug level above therapeutic | 31.61 | 10.96 | 28 | 80842 | 3017 | 64414845 |
Sinusitis | 31.35 | 10.96 | 87 | 80783 | 145841 | 64272021 |
Intentional product misuse | 30.97 | 10.96 | 27 | 80843 | 72268 | 64345594 |
Injection site reaction | 30.86 | 10.96 | 10 | 80860 | 46654 | 64371208 |
Melaena | 30.79 | 10.96 | 141 | 80729 | 53407 | 64364455 |
Embolic stroke | 30.78 | 10.96 | 40 | 80830 | 6671 | 64411191 |
Influenza | 30.71 | 10.96 | 54 | 80816 | 106477 | 64311385 |
Ocular retrobulbar haemorrhage | 30.67 | 10.96 | 10 | 80860 | 129 | 64417733 |
Hepatic enzyme increased | 30.57 | 10.96 | 74 | 80796 | 129869 | 64287993 |
Blood loss anaemia | 30.41 | 10.96 | 59 | 80811 | 13833 | 64404029 |
Chest wall haematoma | 30.36 | 10.96 | 13 | 80857 | 370 | 64417492 |
Tongue haematoma | 29.77 | 10.96 | 11 | 80859 | 210 | 64417652 |
Device related thrombosis | 29.63 | 10.96 | 23 | 80847 | 2062 | 64415800 |
Activated partial thromboplastin time shortened | 29.60 | 10.96 | 16 | 80854 | 769 | 64417093 |
Cardiac valve replacement complication | 29.49 | 10.96 | 11 | 80859 | 216 | 64417646 |
Confusional state | 29.44 | 10.96 | 199 | 80671 | 260945 | 64156917 |
Embolic cerebral infarction | 29.34 | 10.96 | 18 | 80852 | 1101 | 64416761 |
Therapeutic product effect incomplete | 29.33 | 10.96 | 53 | 80817 | 103429 | 64314433 |
Leukocytosis | 29.30 | 10.96 | 109 | 80761 | 37631 | 64380231 |
Graft thrombosis | 29.09 | 10.96 | 13 | 80857 | 411 | 64417451 |
Back pain | 29.02 | 10.96 | 189 | 80681 | 249982 | 64167880 |
Vascular access site haemorrhage | 28.96 | 10.96 | 7 | 80863 | 26 | 64417836 |
Neutrophil count increased | 28.83 | 10.96 | 83 | 80787 | 25091 | 64392771 |
Bullous haemorrhagic dermatosis | 28.65 | 10.96 | 8 | 80862 | 58 | 64417804 |
Hypertransaminasaemia | 28.62 | 10.96 | 40 | 80830 | 7151 | 64410711 |
Anti-platelet antibody | 28.61 | 10.96 | 6 | 80864 | 9 | 64417853 |
Irritable bowel syndrome | 28.53 | 10.96 | 6 | 80864 | 37363 | 64380499 |
Atrial fibrillation | 28.49 | 10.96 | 334 | 80536 | 170755 | 64247107 |
Toxoplasmosis | 28.46 | 10.96 | 24 | 80846 | 2420 | 64415442 |
Pituitary apoplexy | 28.30 | 10.96 | 10 | 80860 | 167 | 64417695 |
Pulmonary haematoma | 28.20 | 10.96 | 9 | 80861 | 108 | 64417754 |
Pulmonary artery thrombosis | 28.10 | 10.96 | 18 | 80852 | 1188 | 64416674 |
Drug chemical incompatibility | 28.08 | 10.96 | 8 | 80862 | 63 | 64417799 |
Rectosigmoid cancer | 27.91 | 10.96 | 11 | 80859 | 252 | 64417610 |
Renal failure | 27.77 | 10.96 | 349 | 80521 | 181339 | 64236523 |
Spinal cord compression | 27.74 | 10.96 | 35 | 80835 | 5668 | 64412194 |
Reperfusion injury | 27.56 | 10.96 | 10 | 80860 | 181 | 64417681 |
Acute generalised exanthematous pustulosis | 27.54 | 10.96 | 57 | 80813 | 14001 | 64403861 |
Fungal sepsis | 27.36 | 10.96 | 20 | 80850 | 1638 | 64416224 |
Procedural hypotension | 27.23 | 10.96 | 21 | 80849 | 1865 | 64415997 |
Sleep disorder | 27.19 | 10.96 | 21 | 80849 | 59688 | 64358174 |
Cytokine release syndrome | 27.15 | 10.96 | 72 | 80798 | 20757 | 64397105 |
Aggression | 27.08 | 10.96 | 12 | 80858 | 46220 | 64371642 |
Injection site pruritus | 27.04 | 10.96 | 7 | 80863 | 37819 | 64380043 |
Epistaxis | 26.98 | 10.96 | 213 | 80657 | 97918 | 64319944 |
Coagulation test abnormal | 26.81 | 10.96 | 17 | 80853 | 1102 | 64416760 |
Aortic dissection | 26.76 | 10.96 | 27 | 80843 | 3425 | 64414437 |
Blood albumin decreased | 26.61 | 10.96 | 72 | 80798 | 21001 | 64396861 |
Renal haemorrhage | 26.56 | 10.96 | 21 | 80849 | 1934 | 64415928 |
Hyperkalaemia | 26.44 | 10.96 | 217 | 80653 | 100912 | 64316950 |
Hepatic infarction | 26.34 | 10.96 | 15 | 80855 | 799 | 64417063 |
Incorrect drug administration rate | 26.25 | 10.96 | 24 | 80846 | 2695 | 64415167 |
Oliguria | 26.12 | 10.96 | 57 | 80813 | 14519 | 64403343 |
Hepatic haematoma | 26.10 | 10.96 | 15 | 80855 | 813 | 64417049 |
Intentional self-injury | 25.93 | 10.96 | 3 | 80867 | 29041 | 64388821 |
Paraplegia | 25.83 | 10.96 | 30 | 80840 | 4460 | 64413402 |
Prosthetic cardiac valve thrombosis | 25.80 | 10.96 | 7 | 80863 | 45 | 64417817 |
Subcapsular renal haematoma | 25.75 | 10.96 | 14 | 80856 | 681 | 64417181 |
Diabetes insipidus | 25.66 | 10.96 | 30 | 80840 | 4491 | 64413371 |
Basal cell carcinoma | 25.60 | 10.96 | 4 | 80866 | 30834 | 64387028 |
Cognitive disorder | 25.56 | 10.96 | 19 | 80851 | 55068 | 64362794 |
Psychotic disorder | 25.50 | 10.96 | 6 | 80864 | 34572 | 64383290 |
Bronchial haemorrhage | 25.45 | 10.96 | 17 | 80853 | 1205 | 64416657 |
Nervous system disorder | 25.38 | 10.96 | 75 | 80795 | 23003 | 64394859 |
Cerebral venous sinus thrombosis | 25.36 | 10.96 | 20 | 80850 | 1835 | 64416027 |
Premature rupture of membranes | 24.93 | 10.96 | 27 | 80843 | 3717 | 64414145 |
Cerebellar haemorrhage | 24.92 | 10.96 | 23 | 80847 | 2614 | 64415248 |
Tachycardia | 24.89 | 10.96 | 292 | 80578 | 149287 | 64268575 |
Dysgeusia | 24.87 | 10.96 | 14 | 80856 | 47033 | 64370829 |
Obstructive shock | 24.69 | 10.96 | 7 | 80863 | 54 | 64417808 |
Cerebral mass effect | 24.64 | 10.96 | 19 | 80851 | 1687 | 64416175 |
Autoimmune heparin-induced thrombocytopenia | 24.48 | 10.96 | 5 | 80865 | 6 | 64417856 |
Abnormal behaviour | 24.47 | 10.96 | 6 | 80864 | 33616 | 64384246 |
Sopor | 24.28 | 10.96 | 4 | 80866 | 29657 | 64388205 |
Stevens-Johnson syndrome | 24.19 | 10.96 | 96 | 80774 | 34153 | 64383709 |
Hydrocephalus | 24.13 | 10.96 | 38 | 80832 | 7553 | 64410309 |
Procedural complication | 23.98 | 10.96 | 37 | 80833 | 7228 | 64410634 |
Dermatitis bullous | 23.76 | 10.96 | 49 | 80821 | 12005 | 64405857 |
Intracranial haematoma | 23.70 | 10.96 | 14 | 80856 | 799 | 64417063 |
Platelet transfusion | 23.64 | 10.96 | 19 | 80851 | 1792 | 64416070 |
Caesarean section | 23.61 | 10.96 | 47 | 80823 | 11227 | 64406635 |
Wrong technique in product usage process | 23.58 | 10.96 | 28 | 80842 | 64946 | 64352916 |
Treatment failure | 23.37 | 10.96 | 72 | 80798 | 116744 | 64301118 |
Dry mouth | 23.05 | 10.96 | 25 | 80845 | 60393 | 64357469 |
Mediastinal haematoma | 23.05 | 10.96 | 9 | 80861 | 201 | 64417661 |
Hypovolaemic shock | 22.96 | 10.96 | 44 | 80826 | 10222 | 64407640 |
Herpes zoster | 22.94 | 10.96 | 40 | 80830 | 79147 | 64338715 |
Aneurysm ruptured | 22.93 | 10.96 | 14 | 80856 | 849 | 64417013 |
Arterial intramural haematoma | 22.82 | 10.96 | 7 | 80863 | 73 | 64417789 |
Cholestasis | 22.79 | 10.96 | 114 | 80756 | 44758 | 64373104 |
Visual impairment | 22.78 | 10.96 | 36 | 80834 | 74041 | 64343821 |
Acquired antithrombin III deficiency | 22.73 | 10.96 | 4 | 80866 | 0 | 64417862 |
Hot flush | 22.70 | 10.96 | 15 | 80855 | 46220 | 64371642 |
Injury | 22.69 | 10.96 | 22 | 80848 | 55970 | 64361892 |
Pancreatic haemorrhage | 22.57 | 10.96 | 7 | 80863 | 76 | 64417786 |
Ischaemia | 22.54 | 10.96 | 36 | 80834 | 7242 | 64410620 |
Device related sepsis | 22.52 | 10.96 | 30 | 80840 | 5125 | 64412737 |
COVID-19 pneumonia | 22.48 | 10.96 | 58 | 80812 | 16446 | 64401416 |
Infusion related reaction | 22.39 | 10.96 | 118 | 80752 | 164349 | 64253513 |
Blood cholesterol increased | 22.30 | 10.96 | 18 | 80852 | 50048 | 64367814 |
Drug dependence | 22.27 | 10.96 | 7 | 80863 | 33305 | 64384557 |
Kounis syndrome | 22.25 | 10.96 | 23 | 80847 | 3002 | 64414860 |
Delayed graft function | 22.18 | 10.96 | 23 | 80847 | 3013 | 64414849 |
Renal artery thrombosis | 22.17 | 10.96 | 11 | 80859 | 442 | 64417420 |
Unresponsive to stimuli | 22.14 | 10.96 | 123 | 80747 | 50270 | 64367592 |
Renal vein thrombosis | 22.08 | 10.96 | 11 | 80859 | 446 | 64417416 |
Protein urine present | 22.05 | 10.96 | 40 | 80830 | 8916 | 64408946 |
Petechiae | 21.90 | 10.96 | 62 | 80808 | 18564 | 64399298 |
Therapeutic product effect increased | 21.74 | 10.96 | 16 | 80854 | 1324 | 64416538 |
Peliosis hepatis | 21.71 | 10.96 | 7 | 80863 | 87 | 64417775 |
Transcription medication error | 21.67 | 10.96 | 10 | 80860 | 341 | 64417521 |
Cerebral artery embolism | 21.21 | 10.96 | 17 | 80853 | 1597 | 64416265 |
Gastrointestinal disorder | 21.17 | 10.96 | 51 | 80819 | 89658 | 64328204 |
Gastric haemorrhage | 21.14 | 10.96 | 50 | 80820 | 13431 | 64404431 |
Cough | 21.06 | 10.96 | 260 | 80610 | 301888 | 64115974 |
Retinal pigment epitheliopathy | 21.04 | 10.96 | 10 | 80860 | 365 | 64417497 |
Medical device site haemorrhage | 20.99 | 10.96 | 8 | 80862 | 167 | 64417695 |
Peritoneal haematoma | 20.95 | 10.96 | 8 | 80862 | 168 | 64417694 |
Cataract | 20.94 | 10.96 | 20 | 80850 | 51242 | 64366620 |
Dry gangrene | 20.90 | 10.96 | 13 | 80857 | 815 | 64417047 |
Contusion | 20.89 | 10.96 | 73 | 80797 | 113892 | 64303970 |
Iliac artery occlusion | 20.86 | 10.96 | 9 | 80861 | 261 | 64417601 |
Vascular graft occlusion | 20.80 | 10.96 | 12 | 80858 | 655 | 64417207 |
Brain death | 20.79 | 10.96 | 28 | 80842 | 4833 | 64413029 |
Inflammation | 20.78 | 10.96 | 31 | 80839 | 65269 | 64352593 |
Heart rate decreased | 20.78 | 10.96 | 23 | 80847 | 55044 | 64362818 |
Toxic skin eruption | 20.57 | 10.96 | 62 | 80808 | 19222 | 64398640 |
Normal newborn | 20.52 | 10.96 | 30 | 80840 | 5587 | 64412275 |
Mucosal erosion | 20.51 | 10.96 | 18 | 80852 | 1916 | 64415946 |
Blood phosphorus increased | 20.41 | 10.96 | 28 | 80842 | 4918 | 64412944 |
Dehydration | 20.25 | 10.96 | 174 | 80696 | 216589 | 64201273 |
Spontaneous haematoma | 20.23 | 10.96 | 15 | 80855 | 1256 | 64416606 |
Intrapericardial thrombosis | 20.06 | 10.96 | 6 | 80864 | 57 | 64417805 |
Serratia infection | 20.02 | 10.96 | 16 | 80854 | 1497 | 64416365 |
Paratonia | 19.83 | 10.96 | 5 | 80865 | 23 | 64417839 |
Post procedural haematoma | 19.72 | 10.96 | 19 | 80851 | 2279 | 64415583 |
Type 2 diabetes mellitus | 19.66 | 10.96 | 9 | 80861 | 34011 | 64383851 |
Wheezing | 19.66 | 10.96 | 45 | 80825 | 80534 | 64337328 |
Protein C decreased | 19.61 | 10.96 | 6 | 80864 | 62 | 64417800 |
Immune effector cell-associated neurotoxicity syndrome | 19.57 | 10.96 | 20 | 80850 | 2575 | 64415287 |
Ascites | 19.54 | 10.96 | 139 | 80731 | 61862 | 64356000 |
Circulatory collapse | 19.52 | 10.96 | 89 | 80781 | 33643 | 64384219 |
Dyspepsia | 19.47 | 10.96 | 45 | 80825 | 80267 | 64337595 |
Osteonecrosis of jaw | 19.45 | 10.96 | 13 | 80857 | 39812 | 64378050 |
Poor quality product administered | 19.37 | 10.96 | 22 | 80848 | 3193 | 64414669 |
Vascular graft thrombosis | 19.36 | 10.96 | 8 | 80862 | 208 | 64417654 |
Irritability | 19.33 | 10.96 | 11 | 80859 | 36735 | 64381127 |
Cerebral amyloid angiopathy | 19.32 | 10.96 | 9 | 80861 | 314 | 64417548 |
Dyspnoea | 19.31 | 10.96 | 722 | 80148 | 717952 | 63699910 |
Cerebral artery occlusion | 19.13 | 10.96 | 16 | 80854 | 1595 | 64416267 |
Aneurysm recanalisation | 19.07 | 10.96 | 4 | 80866 | 6 | 64417856 |
Choroidal effusion | 19.06 | 10.96 | 11 | 80859 | 601 | 64417261 |
Bleeding time prolonged | 18.88 | 10.96 | 14 | 80856 | 1172 | 64416690 |
Infection | 18.82 | 10.96 | 145 | 80725 | 184735 | 64233127 |
Pruritus | 18.81 | 10.96 | 277 | 80593 | 312123 | 64105739 |
Abdominal compartment syndrome | 18.68 | 10.96 | 15 | 80855 | 1413 | 64416449 |
Subcutaneous haematoma | 18.48 | 10.96 | 19 | 80851 | 2464 | 64415398 |
Catheter site haematoma | 18.48 | 10.96 | 9 | 80861 | 347 | 64417515 |
Abdominal pain upper | 18.42 | 10.96 | 136 | 80734 | 174894 | 64242968 |
Tooth disorder | 18.38 | 10.96 | 3 | 80867 | 22399 | 64395463 |
Mean cell haemoglobin concentration | 18.32 | 10.96 | 5 | 80865 | 33 | 64417829 |
False negative investigation result | 18.26 | 10.96 | 8 | 80862 | 241 | 64417621 |
Foetal growth restriction | 18.14 | 10.96 | 16 | 80854 | 1714 | 64416148 |
Mouth ulceration | 18.11 | 10.96 | 9 | 80861 | 32435 | 64385427 |
Tonsillar haemorrhage | 18.08 | 10.96 | 8 | 80862 | 247 | 64417615 |
Live birth | 18.05 | 10.96 | 42 | 80828 | 11162 | 64406700 |
Agitation | 18.01 | 10.96 | 54 | 80816 | 88313 | 64329549 |
Breast cancer | 17.98 | 10.96 | 7 | 80863 | 29141 | 64388721 |
Ventricular asystole | 17.90 | 10.96 | 8 | 80862 | 253 | 64417609 |
Dry eye | 17.85 | 10.96 | 7 | 80863 | 29012 | 64388850 |
Adverse event | 17.84 | 10.96 | 14 | 80856 | 39475 | 64378387 |
Vision blurred | 17.83 | 10.96 | 56 | 80814 | 90260 | 64327602 |
Hypernatraemia | 17.82 | 10.96 | 44 | 80826 | 12145 | 64405717 |
No adverse event | 17.77 | 10.96 | 77 | 80793 | 28484 | 64389378 |
Treatment noncompliance | 17.72 | 10.96 | 17 | 80853 | 43465 | 64374397 |
Primary adrenal insufficiency | 17.70 | 10.96 | 6 | 80864 | 88 | 64417774 |
Upper gastrointestinal haemorrhage | 17.55 | 10.96 | 89 | 80781 | 35131 | 64382731 |
Dysstasia | 17.17 | 10.96 | 4 | 80866 | 23211 | 64394651 |
Bronchitis | 17.15 | 10.96 | 74 | 80796 | 108669 | 64309193 |
International normalised ratio increased | 17.13 | 10.96 | 163 | 80707 | 79004 | 64338858 |
Malignant neoplasm progression | 17.08 | 10.96 | 78 | 80792 | 112793 | 64305069 |
Anisochromia | 17.05 | 10.96 | 3 | 80867 | 0 | 64417862 |
Acne | 17.03 | 10.96 | 4 | 80866 | 23077 | 64394785 |
Fibromyalgia | 17.00 | 10.96 | 12 | 80858 | 35719 | 64382143 |
Complications of transplanted kidney | 16.99 | 10.96 | 27 | 80843 | 5408 | 64412454 |
Drug withdrawal syndrome | 16.99 | 10.96 | 9 | 80861 | 31282 | 64386580 |
Burkholderia test positive | 16.96 | 10.96 | 10 | 80860 | 569 | 64417293 |
Cerebral venous thrombosis | 16.95 | 10.96 | 18 | 80852 | 2423 | 64415439 |
Red blood cell sedimentation rate increased | 16.93 | 10.96 | 9 | 80861 | 31226 | 64386636 |
Livedo reticularis | 16.90 | 10.96 | 22 | 80848 | 3675 | 64414187 |
Arterial rupture | 16.89 | 10.96 | 11 | 80859 | 747 | 64417115 |
Nausea | 16.80 | 10.96 | 810 | 80060 | 784990 | 63632872 |
Depressed mood | 16.75 | 10.96 | 16 | 80854 | 40996 | 64376866 |
Rash morbilliform | 16.71 | 10.96 | 26 | 80844 | 5115 | 64412747 |
Haemodialysis complication | 16.71 | 10.96 | 8 | 80862 | 297 | 64417565 |
Leg amputation | 16.62 | 10.96 | 21 | 80849 | 3406 | 64414456 |
Acute right ventricular failure | 16.58 | 10.96 | 8 | 80862 | 302 | 64417560 |
Gestational hypertension | 16.55 | 10.96 | 15 | 80855 | 1666 | 64416196 |
Thrombin time abnormal | 16.52 | 10.96 | 4 | 80866 | 15 | 64417847 |
Osteoporosis | 16.52 | 10.96 | 17 | 80853 | 42063 | 64375799 |
Haemoglobin increased | 16.48 | 10.96 | 26 | 80844 | 5175 | 64412687 |
White blood cell count decreased | 16.44 | 10.96 | 123 | 80747 | 157714 | 64260148 |
Paraesthesia | 16.42 | 10.96 | 100 | 80770 | 134422 | 64283440 |
Fibrin D dimer increased | 16.38 | 10.96 | 30 | 80840 | 6735 | 64411127 |
Premature labour | 16.24 | 10.96 | 32 | 80838 | 7588 | 64410274 |
Enterococcal infection | 16.15 | 10.96 | 46 | 80824 | 13820 | 64404042 |
Urea renal clearance decreased | 16.12 | 10.96 | 4 | 80866 | 17 | 64417845 |
Pericardial effusion | 16.05 | 10.96 | 94 | 80776 | 39160 | 64378702 |
Renal impairment | 16.02 | 10.96 | 248 | 80622 | 134769 | 64283093 |
Subclavian vein thrombosis | 15.96 | 10.96 | 17 | 80853 | 2297 | 64415565 |
Palpitations | 15.93 | 10.96 | 72 | 80798 | 104416 | 64313446 |
Cardiovascular insufficiency | 15.88 | 10.96 | 18 | 80852 | 2606 | 64415256 |
Coronary artery aneurysm | 15.75 | 10.96 | 6 | 80864 | 125 | 64417737 |
Transfusion | 15.70 | 10.96 | 54 | 80816 | 17940 | 64399922 |
Intracranial pressure increased | 15.69 | 10.96 | 30 | 80840 | 6959 | 64410903 |
Tremor | 15.68 | 10.96 | 115 | 80755 | 148115 | 64269747 |
Stillbirth | 15.65 | 10.96 | 21 | 80849 | 3612 | 64414250 |
Alveolitis necrotising | 15.59 | 10.96 | 4 | 80866 | 20 | 64417842 |
Haemorrhage subcutaneous | 15.51 | 10.96 | 23 | 80847 | 4338 | 64413524 |
Urethral fistula | 15.43 | 10.96 | 4 | 80866 | 21 | 64417841 |
Acute pulmonary oedema | 15.41 | 10.96 | 43 | 80827 | 12766 | 64405096 |
Alanine aminotransferase decreased | 15.35 | 10.96 | 13 | 80857 | 1319 | 64416543 |
Platelet dysfunction | 15.35 | 10.96 | 8 | 80862 | 357 | 64417505 |
Incision site haematoma | 15.24 | 10.96 | 6 | 80864 | 137 | 64417725 |
HELLP syndrome | 15.22 | 10.96 | 10 | 80860 | 689 | 64417173 |
Peritonitis | 15.22 | 10.96 | 67 | 80803 | 24956 | 64392906 |
Accidental exposure to product | 15.19 | 10.96 | 7 | 80863 | 26357 | 64391505 |
Vertigo | 15.18 | 10.96 | 32 | 80838 | 58979 | 64358883 |
Pelvic haematoma | 15.17 | 10.96 | 10 | 80860 | 693 | 64417169 |
Coronary artery dissection | 15.07 | 10.96 | 11 | 80859 | 899 | 64416963 |
Adverse drug reaction | 15.04 | 10.96 | 21 | 80849 | 45443 | 64372419 |
Gastric disorder | 14.99 | 10.96 | 9 | 80861 | 29188 | 64388674 |
Capillary fragility test | 14.98 | 10.96 | 4 | 80866 | 24 | 64417838 |
Hand amputation | 14.97 | 10.96 | 3 | 80867 | 3 | 64417859 |
Overdose | 14.93 | 10.96 | 128 | 80742 | 159438 | 64258424 |
Pulse absent | 14.92 | 10.96 | 34 | 80836 | 8912 | 64408950 |
Myiasis | 14.84 | 10.96 | 4 | 80866 | 25 | 64417837 |
Emotional distress | 14.79 | 10.96 | 14 | 80856 | 36024 | 64381838 |
Body temperature decreased | 14.76 | 10.96 | 7 | 80863 | 25921 | 64391941 |
Haemobilia | 14.72 | 10.96 | 8 | 80862 | 389 | 64417473 |
Cerebrovascular disorder | 14.66 | 10.96 | 20 | 80850 | 3495 | 64414367 |
Haemorrhagic cholecystitis | 14.65 | 10.96 | 5 | 80865 | 75 | 64417787 |
Multiple sclerosis relapse | 14.64 | 10.96 | 18 | 80852 | 41117 | 64376745 |
Influenza like illness | 14.61 | 10.96 | 35 | 80835 | 61667 | 64356195 |
Gait inability | 14.59 | 10.96 | 19 | 80851 | 42349 | 64375513 |
Threatened labour | 14.59 | 10.96 | 9 | 80861 | 556 | 64417306 |
Platelet aggregation abnormal | 14.57 | 10.96 | 4 | 80866 | 27 | 64417835 |
Thrombectomy | 14.57 | 10.96 | 7 | 80863 | 262 | 64417600 |
Neuropathy peripheral | 14.53 | 10.96 | 87 | 80783 | 117438 | 64300424 |
Injection site plaque | 14.52 | 10.96 | 5 | 80865 | 77 | 64417785 |
Blood thrombin increased | 14.51 | 10.96 | 3 | 80867 | 4 | 64417858 |
Speech disorder | 14.46 | 10.96 | 24 | 80846 | 48417 | 64369445 |
Blood blister | 14.29 | 10.96 | 17 | 80853 | 2591 | 64415271 |
Pulmonary fibrosis | 14.26 | 10.96 | 10 | 80860 | 29868 | 64387994 |
Right ventricular failure | 14.22 | 10.96 | 59 | 80811 | 21412 | 64396450 |
Sleep apnoea syndrome | 14.22 | 10.96 | 10 | 80860 | 29822 | 64388040 |
Pseudomonas infection | 14.17 | 10.96 | 52 | 80818 | 17831 | 64400031 |
Pulmonary oedema | 14.17 | 10.96 | 156 | 80714 | 78518 | 64339344 |
Stomatitis | 14.16 | 10.96 | 80 | 80790 | 109525 | 64308337 |
Stress cardiomyopathy | 14.15 | 10.96 | 34 | 80836 | 9223 | 64408639 |
Microstomia | 14.11 | 10.96 | 3 | 80867 | 5 | 64417857 |
Orthostatic hypotension | 14.10 | 10.96 | 23 | 80847 | 46715 | 64371147 |
Nasal congestion | 14.00 | 10.96 | 34 | 80836 | 59624 | 64358238 |
Nervousness | 13.96 | 10.96 | 10 | 80860 | 29546 | 64388316 |
Cholestatic liver injury | 13.95 | 10.96 | 20 | 80850 | 3659 | 64414203 |
Breast haematoma | 13.94 | 10.96 | 6 | 80864 | 173 | 64417689 |
Carotid intima-media thickness increased | 13.91 | 10.96 | 5 | 80865 | 88 | 64417774 |
Inferior vena caval occlusion | 13.87 | 10.96 | 4 | 80866 | 33 | 64417829 |
Graft haemorrhage | 13.81 | 10.96 | 5 | 80865 | 90 | 64417772 |
Blood pressure increased | 13.76 | 10.96 | 144 | 80726 | 172408 | 64245454 |
Cerebellar embolism | 13.76 | 10.96 | 3 | 80867 | 6 | 64417856 |
Migraine | 13.73 | 10.96 | 37 | 80833 | 62640 | 64355222 |
Hyperlactacidaemia | 13.70 | 10.96 | 23 | 80847 | 4821 | 64413041 |
Phaeochromocytoma crisis | 13.69 | 10.96 | 7 | 80863 | 300 | 64417562 |
Thrombolysis | 13.69 | 10.96 | 6 | 80864 | 181 | 64417681 |
Drug ineffective for unapproved indication | 13.68 | 10.96 | 76 | 80794 | 31057 | 64386805 |
Brain stem infarction | 13.66 | 10.96 | 14 | 80856 | 1809 | 64416053 |
Night sweats | 13.66 | 10.96 | 15 | 80855 | 36031 | 64381831 |
Transmission of an infectious agent via product | 13.66 | 10.96 | 6 | 80864 | 182 | 64417680 |
Splenic haemorrhage | 13.58 | 10.96 | 9 | 80861 | 629 | 64417233 |
Hypertensive nephropathy | 13.55 | 10.96 | 10 | 80860 | 831 | 64417031 |
Delusion | 13.53 | 10.96 | 3 | 80867 | 18011 | 64399851 |
Bursitis | 13.52 | 10.96 | 5 | 80865 | 21480 | 64396382 |
Extraocular muscle disorder | 13.52 | 10.96 | 7 | 80863 | 308 | 64417554 |
Myocardial haemorrhage | 13.47 | 10.96 | 4 | 80866 | 37 | 64417825 |
Joint stiffness | 13.45 | 10.96 | 11 | 80859 | 30393 | 64387469 |
Amnesia | 13.43 | 10.96 | 25 | 80845 | 48244 | 64369618 |
Paradoxical embolism | 13.37 | 10.96 | 4 | 80866 | 38 | 64417824 |
Lipoedema | 13.36 | 10.96 | 6 | 80864 | 192 | 64417670 |
Distributive shock | 13.33 | 10.96 | 14 | 80856 | 1861 | 64416001 |
Heart rate irregular | 13.32 | 10.96 | 9 | 80861 | 27404 | 64390458 |
Factor VIII inhibition | 13.31 | 10.96 | 7 | 80863 | 318 | 64417544 |
Ventricular arrhythmia | 13.29 | 10.96 | 29 | 80841 | 7386 | 64410476 |
Syncope | 13.21 | 10.96 | 130 | 80740 | 157505 | 64260357 |
Portal vein thrombosis | 13.20 | 10.96 | 23 | 80847 | 4968 | 64412894 |
Left ventricular dysfunction | 13.18 | 10.96 | 49 | 80821 | 16905 | 64400957 |
Vascular parkinsonism | 13.18 | 10.96 | 5 | 80865 | 103 | 64417759 |
Vascular access site haematoma | 13.16 | 10.96 | 3 | 80867 | 8 | 64417854 |
Carotid artery dissection | 13.13 | 10.96 | 7 | 80863 | 327 | 64417535 |
Product contamination microbial | 13.12 | 10.96 | 10 | 80860 | 873 | 64416989 |
Throat irritation | 13.08 | 10.96 | 13 | 80857 | 32698 | 64385164 |
Nightmare | 13.02 | 10.96 | 5 | 80865 | 20988 | 64396874 |
Kidney rupture | 12.99 | 10.96 | 6 | 80864 | 205 | 64417657 |
Basophil count decreased | 12.97 | 10.96 | 6 | 80864 | 206 | 64417656 |
Necrotising oesophagitis | 12.94 | 10.96 | 9 | 80861 | 681 | 64417181 |
Hypertriglyceridaemia | 12.88 | 10.96 | 37 | 80833 | 11168 | 64406694 |
Antithrombin III deficiency | 12.88 | 10.96 | 5 | 80865 | 110 | 64417752 |
Mouth haemorrhage | 12.85 | 10.96 | 34 | 80836 | 9785 | 64408077 |
Injection site bruising | 12.85 | 10.96 | 16 | 80854 | 36357 | 64381505 |
Hypoxic-ischaemic encephalopathy | 12.85 | 10.96 | 28 | 80842 | 7124 | 64410738 |
Eosinophil cationic protein increased | 12.85 | 10.96 | 4 | 80866 | 44 | 64417818 |
Thoracic haemorrhage | 12.78 | 10.96 | 6 | 80864 | 213 | 64417649 |
Basal ganglia haemorrhage | 12.78 | 10.96 | 12 | 80858 | 1394 | 64416468 |
Purpura | 12.71 | 10.96 | 49 | 80821 | 17197 | 64400665 |
Nephrolithiasis | 12.71 | 10.96 | 22 | 80848 | 43661 | 64374201 |
Platelet disorder | 12.69 | 10.96 | 15 | 80855 | 2272 | 64415590 |
Product preparation error | 12.66 | 10.96 | 20 | 80850 | 3985 | 64413877 |
Ruptured cerebral aneurysm | 12.61 | 10.96 | 8 | 80862 | 519 | 64417343 |
Klebsiella infection | 12.60 | 10.96 | 41 | 80829 | 13240 | 64404622 |
COVID-19 | 12.58 | 10.96 | 131 | 80739 | 65009 | 64352853 |
Diabetes mellitus | 12.57 | 10.96 | 42 | 80828 | 66432 | 64351430 |
Blood pressure systolic increased | 12.57 | 10.96 | 27 | 80843 | 49426 | 64368436 |
Aspartate aminotransferase decreased | 12.56 | 10.96 | 10 | 80860 | 930 | 64416932 |
Dystonia | 12.55 | 10.96 | 4 | 80866 | 18861 | 64399001 |
Kidney transplant rejection | 12.52 | 10.96 | 33 | 80837 | 9478 | 64408384 |
Spinal cord haemorrhage | 12.50 | 10.96 | 8 | 80862 | 527 | 64417335 |
Respiratory tract oedema | 12.49 | 10.96 | 9 | 80861 | 721 | 64417141 |
Postpartum haemorrhage | 12.49 | 10.96 | 12 | 80858 | 1435 | 64416427 |
Manufacturing materials issue | 12.44 | 10.96 | 3 | 80867 | 11 | 64417851 |
Myelomalacia | 12.36 | 10.96 | 5 | 80865 | 123 | 64417739 |
Food interaction | 12.35 | 10.96 | 12 | 80858 | 1454 | 64416408 |
Nutritional condition abnormal | 12.32 | 10.96 | 10 | 80860 | 956 | 64416906 |
Fear | 12.19 | 10.96 | 5 | 80865 | 20166 | 64397696 |
Bone disorder | 12.18 | 10.96 | 3 | 80867 | 16756 | 64401106 |
Peripheral artery aneurysm | 12.14 | 10.96 | 7 | 80863 | 382 | 64417480 |
Hepatic cytolysis | 12.11 | 10.96 | 42 | 80828 | 14007 | 64403855 |
Electrocardiogram T wave alternans | 12.10 | 10.96 | 4 | 80866 | 54 | 64417808 |
Femur fracture | 12.08 | 10.96 | 15 | 80855 | 34120 | 64383742 |
Arterial injury | 12.04 | 10.96 | 8 | 80862 | 562 | 64417300 |
Skin ulcer | 12.03 | 10.96 | 23 | 80847 | 43951 | 64373911 |
Bacteraemia | 12.03 | 10.96 | 66 | 80804 | 26845 | 64391017 |
Sedation | 11.96 | 10.96 | 21 | 80849 | 41441 | 64376421 |
Traumatic haemothorax | 11.95 | 10.96 | 7 | 80863 | 393 | 64417469 |
White blood cell count increased | 11.93 | 10.96 | 131 | 80739 | 65883 | 64351979 |
Ulcer | 11.92 | 10.96 | 7 | 80863 | 22983 | 64394879 |
Vaginal haemorrhage | 11.92 | 10.96 | 52 | 80818 | 19292 | 64398570 |
Activated partial thromboplastin time abnormal | 11.91 | 10.96 | 6 | 80864 | 249 | 64417613 |
Venous thrombosis limb | 11.91 | 10.96 | 19 | 80851 | 3818 | 64414044 |
Foot deformity | 11.90 | 10.96 | 3 | 80867 | 16501 | 64401361 |
Pneumonia escherichia | 11.89 | 10.96 | 9 | 80861 | 777 | 64417085 |
Ergot poisoning | 11.85 | 10.96 | 5 | 80865 | 137 | 64417725 |
Contrast encephalopathy | 11.82 | 10.96 | 5 | 80865 | 138 | 64417724 |
Renal tubular necrosis | 11.81 | 10.96 | 57 | 80813 | 22053 | 64395809 |
Paranoia | 11.74 | 10.96 | 3 | 80867 | 16349 | 64401513 |
Dyspnoea exertional | 11.73 | 10.96 | 50 | 80820 | 73680 | 64344182 |
Ureteric haemorrhage | 11.69 | 10.96 | 3 | 80867 | 15 | 64417847 |
Septic rash | 11.69 | 10.96 | 3 | 80867 | 15 | 64417847 |
Femoral nerve palsy | 11.66 | 10.96 | 4 | 80866 | 61 | 64417801 |
Platelet aggregation test | 11.66 | 10.96 | 4 | 80866 | 61 | 64417801 |
Extravasation | 11.64 | 10.96 | 17 | 80853 | 3163 | 64414699 |
Blister | 11.63 | 10.96 | 57 | 80813 | 80910 | 64336952 |
Tracheal haemorrhage | 11.59 | 10.96 | 8 | 80862 | 598 | 64417264 |
Coronary artery occlusion | 11.52 | 10.96 | 41 | 80829 | 13850 | 64404012 |
Cerebral artery thrombosis | 11.52 | 10.96 | 10 | 80860 | 1049 | 64416813 |
Blood sodium decreased | 11.47 | 10.96 | 12 | 80858 | 29470 | 64388392 |
Anaphylactoid reaction | 11.46 | 10.96 | 21 | 80849 | 4717 | 64413145 |
Abortion early | 11.38 | 10.96 | 3 | 80867 | 17 | 64417845 |
Cardiac failure | 11.37 | 10.96 | 231 | 80639 | 132142 | 64285720 |
Haematidrosis | 11.37 | 10.96 | 4 | 80866 | 66 | 64417796 |
Lumbar puncture | 11.34 | 10.96 | 5 | 80865 | 153 | 64417709 |
Spinal cord disorder | 11.31 | 10.96 | 12 | 80858 | 1614 | 64416248 |
Premature baby | 11.27 | 10.96 | 17 | 80853 | 3255 | 64414607 |
Immune thrombocytopenia | 11.26 | 10.96 | 43 | 80827 | 15023 | 64402839 |
Herpes simplex hepatitis | 11.26 | 10.96 | 7 | 80863 | 438 | 64417424 |
Fungal disease carrier | 11.24 | 10.96 | 6 | 80864 | 281 | 64417581 |
Microangiopathic haemolytic anaemia | 11.20 | 10.96 | 11 | 80859 | 1351 | 64416511 |
Staphylococcus test positive | 11.19 | 10.96 | 23 | 80847 | 5622 | 64412240 |
Paralysis | 11.18 | 10.96 | 36 | 80834 | 11559 | 64406303 |
Mediastinal haemorrhage | 11.15 | 10.96 | 4 | 80866 | 70 | 64417792 |
Reperfusion arrhythmia | 11.15 | 10.96 | 6 | 80864 | 286 | 64417576 |
Hypoaesthesia | 11.13 | 10.96 | 116 | 80754 | 138992 | 64278870 |
Toothache | 11.09 | 10.96 | 4 | 80866 | 17455 | 64400407 |
Anger | 11.09 | 10.96 | 3 | 80867 | 15738 | 64402124 |
Organic brain syndrome | 11.08 | 10.96 | 7 | 80863 | 451 | 64417411 |
Renal artery stenosis | 11.05 | 10.96 | 16 | 80854 | 2953 | 64414909 |
Hyperglycaemia | 11.02 | 10.96 | 121 | 80749 | 60847 | 64357015 |
Pituitary haemorrhage | 10.99 | 10.96 | 6 | 80864 | 294 | 64417568 |
Movement disorder | 10.99 | 10.96 | 7 | 80863 | 21993 | 64395869 |
Subdural haemorrhage | 10.98 | 10.96 | 22 | 80848 | 5281 | 64412581 |
None
Source | Code | Description |
---|---|---|
ATC | B01AB01 | BLOOD AND BLOOD FORMING ORGANS ANTITHROMBOTIC AGENTS ANTITHROMBOTIC AGENTS Heparin group |
ATC | B01AB51 | BLOOD AND BLOOD FORMING ORGANS ANTITHROMBOTIC AGENTS ANTITHROMBOTIC AGENTS Heparin group |
ATC | C05BA03 | CARDIOVASCULAR SYSTEM VASOPROTECTIVES ANTIVARICOSE THERAPY Heparins or heparinoids for topical use |
ATC | C05BA53 | CARDIOVASCULAR SYSTEM VASOPROTECTIVES ANTIVARICOSE THERAPY Heparins or heparinoids for topical use |
ATC | S01XA14 | SENSORY ORGANS OPHTHALMOLOGICALS OTHER OPHTHALMOLOGICALS Other ophthalmologicals |
FDA CS | M0010187 | Heparin |
FDA EPC | N0000175474 | Unfractionated Heparin |
MeSH PA | D000925 | Anticoagulants |
MeSH PA | D002317 | Cardiovascular Agents |
MeSH PA | D005343 | Fibrinolytic Agents |
MeSH PA | D006401 | Hematologic Agents |
FDA EPC | N0000175980 | Anti-coagulant |
CHEBI has role | CHEBI:50249 | anticoagulants |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Disseminated intravascular coagulation | indication | 67406007 | DOID:11247 |
Deep venous thrombosis | indication | 128053003 | |
Pulmonary thromboembolism | indication | 233935004 | |
Peripheral arterial embolism | indication | 286959000 | |
Non-Q wave myocardial infarction | indication | 314207007 | |
Prevention of deep vein thrombosis | indication | 439993001 | |
Deep Vein Thrombosis with Pulmonary Embolism | indication | ||
Prevention of Recurrent Venous Thrombosis Associated with Malignancy | indication | ||
Pulmonary Thromboembolism Prevention | indication | ||
Peripheral Arterial Thromboembolism Prevention | indication | ||
Maintain Patency of Indwelling Vascular Catheter | indication | ||
Prevention of Ischemic Complications of Non-Q Wave MI | indication | ||
Prevention of Cardiac Ischemia in Unstable Angina | indication | ||
Myocardial infarction | off-label use | 22298006 | DOID:5844 |
Coronavirus infection | off-label use | 186747009 | |
Acute coronary syndrome | off-label use | 394659003 | |
Percutaneous coronary intervention | off-label use | 415070008 | |
Intracranial hemorrhage | contraindication | 1386000 | |
Diabetic retinopathy | contraindication | 4855003 | DOID:8947 |
Hypertensive retinopathy | contraindication | 6962006 | DOID:11561 |
Retinal disorder | contraindication | 29555009 | DOID:5679 |
Antithrombin III deficiency | contraindication | 36351005 | DOID:3755 |
Gastrointestinal ulcer | contraindication | 40845000 | |
Threatened abortion | contraindication | 54048003 | DOID:9667 |
Acute nephropathy | contraindication | 58574008 | |
Hepatic failure | contraindication | 59927004 | |
Ulcerative colitis | contraindication | 64766004 | DOID:8577 |
Blood coagulation disorder | contraindication | 64779008 | DOID:1247 |
Osteoporosis | contraindication | 64859006 | DOID:11476 |
Operation on brain | contraindication | 70586009 | |
Heparin-induced thrombocytopenia | contraindication | 73397007 | |
Gastrointestinal hemorrhage | contraindication | 74474003 | |
Ulceration of intestine | contraindication | 85942002 | |
Acute gastric ulcer with hemorrhage | contraindication | 89748001 | |
Hemophilia | contraindication | 90935002 | |
Disorder of biliary tract | contraindication | 105997008 | DOID:9741 |
Procedure on central nervous system | contraindication | 118679007 | |
Bleeding | contraindication | 131148009 | |
Disease of blood AND/OR blood-forming organ | contraindication | 191124002 | DOID:74 |
Hemorrhagic cerebral infarction | contraindication | 230706003 | |
Local anesthetic intrathecal block | contraindication | 231249005 | |
Infective endocarditis | contraindication | 233850007 | |
Procedure on spine | contraindication | 238181003 | |
Qualitative platelet disorder | contraindication | 267532001 | |
Diverticulitis of gastrointestinal tract | contraindication | 271366000 | |
Cerebral hemorrhage | contraindication | 274100004 | |
Lumbar puncture | contraindication | 277762005 | |
Bacterial endocarditis | contraindication | 301183007 | |
Thrombocytopenic disorder | contraindication | 302215000 | DOID:1588 |
Dissection of aorta | contraindication | 308546005 | |
Arteriosclerosis obliterans | contraindication | 361133006 | DOID:5160 |
Surgical procedure on eye proper | contraindication | 373353005 | |
Hypertensive urgency | contraindication | 443482000 | |
Placement of Epidural Catheter | contraindication | ||
Thrombosis in Heparin Induced Thrombocytopenia | contraindication | ||
Platelet Aggregation Inhibition | contraindication | ||
Spinal Epidural Hematoma | contraindication | ||
Significant Bleeding | contraindication | ||
Indwelling Vascular Catheter | contraindication |
None
None
None
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Antithrombin-III | Secreted | ACTIVATOR | Kd | 7.85 | IUPHAR | CHEMBL | |||
Spike glycoprotein | Glycoprotein | Kd | 10.14 | IUPHAR | |||||
Spike glycoprotein, S glycoprotein | Unclassified | Kd | 6.30 | IUPHAR |
ID | Source |
---|---|
D02112 | KEGG_DRUG |
4017546 | VANDF |
4017547 | VANDF |
4017549 | VANDF |
4018538 | VANDF |
C0019134 | UMLSCUI |
CHEBI:28304 | CHEBI |
CHEMBL1909300 | ChEMBL_ID |
CHEMBL4650299 | ChEMBL_ID |
CHEMBL1201657 | ChEMBL_ID |
D006493 | MESH_DESCRIPTOR_UI |
DB01109 | DRUGBANK_ID |
4214 | IUPHAR_LIGAND_ID |
37270-89-6 | SECONDARY_CAS_RN |
T2410KM04A | UNII |
92044406 | PUBCHEM_CID |
20044 | RXNORM |
3649 | MMSL |
4821 | MMSL |
d00252 | MMSL |
002079 | NDDF |
002081 | NDDF |
015153 | NDDF |
29725000 | SNOMEDCT_US |
372877000 | SNOMEDCT_US |
412201008 | SNOMEDCT_US |
412401006 | SNOMEDCT_US |
50045009 | SNOMEDCT_US |
784398008 | SNOMEDCT_US |
84812008 | SNOMEDCT_US |
CHEMBL1201513 | ChEMBL_ID |
M7J | PDB_CHEM_ID |
392 | INN_ID |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Heparin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-0043 | INJECTION | 1000 [USPU] | INTRAVENOUS | NDA | 26 sections |
Heparin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-0058 | INJECTION | 1000 [USPU] | INTRAVENOUS | NDA | 26 sections |
Heparin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-0059 | INJECTION | 5000 [USPU] | INTRAVENOUS | NDA | 26 sections |
Heparin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-0062 | INJECTION | 10000 [USPU] | INTRAVENOUS | NDA | 26 sections |
Heparin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-0137 | INJECTION | 1000 [USPU] | INTRAVENOUS | NDA | 26 sections |
Heparin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0264-5705 | INJECTION | 5000 [USPU] | INTRAVENOUS | ANDA | 20 sections |
Heparin Sodium in Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0264-9567 | INJECTION | 4000 [USPU] | INTRAVENOUS | NDA | 19 sections |
Heparin Sodium in Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0264-9577 | INJECTION | 5000 [USPU] | INTRAVENOUS | NDA | 19 sections |
Heparin Sodium in Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0264-9587 | INJECTION | 10000 [USPU] | INTRAVENOUS | NDA | 19 sections |
Heparin Sodium in Sodium Chloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0264-9872 | INJECTION | 200 [USPU] | INTRAVENOUS | NDA | 23 sections |
HEPARIN SODIUM IN SODIUM CHLORIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0424 | INJECTION, SOLUTION | 200 [USPU] | INTRAVENOUS | NDA | 26 sections |
HEPARIN SODIUM IN SODIUM CHLORIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0428 | INJECTION, SOLUTION | 200 [USPU] | INTRAVENOUS | NDA | 26 sections |
HEPARIN SODIUM IN SODIUM CHLORIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0431 | INJECTION, SOLUTION | 200 [USPU] | INTRAVENOUS | NDA | 26 sections |
HEPARIN SODIUM IN SODIUM CHLORIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0433 | INJECTION, SOLUTION | 200 [USPU] | INTRAVENOUS | NDA | 26 sections |
Heparin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0404-9872 | INJECTION, SOLUTION | 5000 [USPU] | INTRAVENOUS | ANDA | 14 sections |
HEPARIN SODIUM | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0404-9873 | INJECTION | 10000 [USPU] | INTRAVENOUS | ANDA | 14 sections |
Heparin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0404-9979 | INJECTION, SOLUTION | 1000 [USPU] | INTRAVENOUS | NDA | 16 sections |
Heparin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-1316 | INJECTION, SOLUTION | 10000 [USPU] | SUBCUTANEOUS | ANDA | 25 sections |
Heparin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-1402 | INJECTION, SOLUTION | 5000 [USPU] | SUBCUTANEOUS | ANDA | 25 sections |
Heparin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-2720 | INJECTION, SOLUTION | 1000 [USPU] | SUBCUTANEOUS | ANDA | 25 sections |
Heparin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-2721 | INJECTION, SOLUTION | 10000 [USPU] | INTRAVENOUS | ANDA | 25 sections |
Heparin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-2723 | INJECTION, SOLUTION | 5000 [USPU] | SUBCUTANEOUS | ANDA | 25 sections |
Heparin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-7620 | INJECTION, SOLUTION | 200 [USPU] | INTRAVENOUS | NDA | 27 sections |
Heparin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-7650 | INJECTION, SOLUTION | 10000 [USPU] | INTRAVENOUS | NDA | 24 sections |
Heparin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-7651 | INJECTION, SOLUTION | 5000 [USPU] | INTRAVENOUS | NDA | 24 sections |
Heparin Sodium and Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-7793 | INJECTION, SOLUTION | 10000 [USPU] | INTRAVENOUS | NDA | 24 sections |
Heparin Sodium and Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-7794 | INJECTION, SOLUTION | 5000 [USPU] | INTRAVENOUS | NDA | 24 sections |
Heparin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0641-0391 | INJECTION | 1000 [USPU] | INTRAVENOUS | NDA | 24 sections |
Heparin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0641-0400 | INJECTION | 5000 [USPU] | INTRAVENOUS | NDA | 24 sections |
Heparin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0641-0410 | INJECTION | 10000 [USPU] | INTRAVENOUS | NDA | 24 sections |