All FDA-approved EMA-approved PMDA-approved
Target Card Uniprot Example: P23975

enoxaparin sodium 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definition	Drug id	CAS RN
heparin derivatives including low molecular mass heparins	4879	679809-58-6

Description:

Molecule	Description
Synonyms: thorinane enoxaparin sodium enoxaparin lovenox enoxaparine	Low-molecular-weight fragment of heparin, having a 4-enopyranosuronate sodium structure at the non-reducing end of the chain. It is prepared by depolymerization of the benzylic ester of porcine mucosal heparin. Therapeutically, it is used as an antithrombotic agent. (From Merck Index, 11th ed) Molecular weight: Formula: None CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: ALOGS: ROTB: None

Drug dosage:

Dose	Unit	Route
2	TU	P

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

Date	Agency	Company	Orphan
March 29, 1993	FDA	SANOFI AVENTIS US
Sept. 15, 2016	EMA	Techdow Pharma Netherlands B.V.

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Haematoma	787.96	10.36	543	119132	38505	90470267
Heparin-induced thrombocytopenia	778.12	10.36	285	119390	5027	90503745
Thrombocytopenia	693.97	10.36	1095	118580	207630	90301142
Abdominal wall haematoma	628.36	10.36	216	119459	3136	90505636
Pulmonary embolism	599.08	10.36	799	118876	130021	90378751
Cholestasis	584.04	10.36	440	119235	35859	90472913
Shock haemorrhagic	578.13	10.36	295	119380	11950	90496822
Acute kidney injury	504.21	10.36	1226	118449	319161	90189611
Anaemia	495.65	10.36	1293	118382	351509	90157263
Deep vein thrombosis	493.98	10.36	607	119068	91013	90417759
Exposure during pregnancy	488.90	10.36	1014	118661	237396	90271376
Retroperitoneal haematoma	486.99	10.36	179	119496	3189	90505583
Acute generalised exanthematous pustulosis	459.27	10.36	263	119412	13440	90495332
Retroperitoneal haemorrhage	446.47	10.36	164	119511	2916	90505856
Joint swelling	420.94	10.36	78	119597	503222	90005550
Pemphigus	414.49	10.36	3	119672	326861	90181911
Hepatic cytolysis	411.31	10.36	335	119340	30581	90478191
Hepatocellular injury	411.22	10.36	326	119349	28632	90480140
Synovitis	392.29	10.36	9	119666	329743	90179029
Injury associated with device	390.76	10.36	165	119510	4299	90504473
Premature delivery	387.97	10.36	357	119318	38405	90470367
Rash maculo-papular	378.96	10.36	361	119314	40572	90468200
Drug ineffective	363.90	10.36	809	118866	1383489	89125283
Drug reaction with eosinophilia and systemic symptoms	358.21	10.36	357	119318	42401	90466371
Systemic lupus erythematosus	354.85	10.36	34	119641	361862	90146910
Rheumatoid arthritis	342.84	10.36	39	119636	362575	90146197
Alopecia	329.82	10.36	121	119554	494950	90013822
Glossodynia	329.75	10.36	25	119650	321754	90187018
Arthropathy	320.95	10.36	50	119625	366192	90142580
Eosinophilia	315.52	10.36	278	119397	28255	90480517
Premature baby	313.25	10.36	262	119413	24815	90483957
Drug intolerance	312.61	10.36	101	119574	447490	90061282
Abdominal discomfort	288.31	10.36	135	119540	477193	90031579
Neutropenia	285.83	10.36	795	118880	224109	90284663
Pericarditis	279.58	10.36	20	119655	270131	90238641
Therapeutic product effect decreased	277.60	10.36	24	119651	277547	90231225
Haemoglobin decreased	277.25	10.36	641	119034	161315	90347457
Psoriatic arthropathy	272.38	10.36	6	119669	228329	90280443
Foetal exposure during pregnancy	268.29	10.36	307	119368	42668	90466104
Haemorrhage	262.62	10.36	387	119288	68982	90439790
Infusion related reaction	262.45	10.36	111	119564	416669	90092103
Wound	261.71	10.36	43	119632	302937	90205835
Muscle haemorrhage	257.77	10.36	113	119562	3233	90505539
Helicobacter infection	255.91	10.36	10	119665	226840	90281932
Weight increased	249.56	10.36	120	119555	417807	90090965
Folliculitis	245.20	10.36	5	119670	204348	90304424
Intra-abdominal haematoma	241.62	10.36	95	119580	2049	90506723
Swelling	235.82	10.36	130	119545	418928	90089844
Fibromyalgia	229.62	10.36	10	119665	206259	90302513
Nasopharyngitis	229.49	10.36	126	119549	406978	90101794
Arthralgia	229.16	10.36	425	119250	778097	89730675
Pain	226.71	10.36	626	119049	995715	89513057
Irritable bowel syndrome	224.69	10.36	12	119663	207436	90301336
Duodenal ulcer perforation	213.62	10.36	22	119653	221266	90287506
Gastrointestinal haemorrhage	209.96	10.36	405	119270	89843	90418929
Discomfort	205.88	10.36	54	119621	274281	90234491
Drug interaction	202.24	10.36	811	118864	275642	90233130
Sinusitis	200.98	10.36	101	119574	342987	90165785
Musculoskeletal stiffness	198.07	10.36	72	119603	296460	90212312
Blood cholesterol increased	197.41	10.36	22	119653	207990	90300782
Thrombosis	193.26	10.36	347	119328	72904	90435868
Hypotension	193.06	10.36	896	118779	324501	90184271
Mixed liver injury	192.49	10.36	122	119553	7501	90501271
International normalised ratio increased	192.24	10.36	273	119402	47043	90461729
Muscle injury	191.98	10.36	10	119665	176644	90332128
Hypersensitivity	190.20	10.36	192	119483	454485	90054287
Febrile neutropenia	185.71	10.36	544	119131	157805	90350967
Drug hypersensitivity	182.52	10.36	206	119469	463403	90045369
Treatment failure	181.74	10.36	87	119588	303841	90204931
Toxic skin eruption	181.03	10.36	157	119518	15617	90493155
Haematuria	179.38	10.36	226	119449	34711	90474061
Pelvic haematoma	176.37	10.36	57	119618	675	90508097
Agranulocytosis	175.88	10.36	224	119451	34778	90473994
Completed suicide	172.22	10.36	4	119671	145054	90363718
Hypoxia	170.96	10.36	327	119348	72072	90436700
Wheezing	169.11	10.36	52	119623	238028	90270744
Type 2 diabetes mellitus	166.45	10.36	33	119642	203211	90305561
Contraindicated product administered	163.72	10.36	111	119564	320028	90188744
Cerebral haemorrhage	159.54	10.36	212	119463	34310	90474462
Sepsis	159.22	10.36	561	119114	179253	90329519
Mobility decreased	157.34	10.36	67	119608	250667	90258105
Haematoma muscle	157.33	10.36	67	119608	1783	90506989
Sleep disorder due to general medical condition, insomnia type	154.95	10.36	3	119672	128691	90380081
Foetal growth restriction	153.69	10.36	115	119560	9265	90499507
C-reactive protein abnormal	153.30	10.36	3	119672	127426	90381346
Therapeutic product effect incomplete	151.60	10.36	35	119640	193861	90314911
Hepatic enzyme increased	151.17	10.36	152	119523	360584	90148188
Hypokalaemia	149.47	10.36	446	119229	130670	90378102
Headache	148.76	10.36	611	119064	862135	89646637
Stomatitis	142.11	10.36	94	119581	274604	90234168
Asthma	140.68	10.36	72	119603	242088	90266684
Clostridium test positive	135.28	10.36	86	119589	5315	90503457
Low birth weight baby	135.27	10.36	107	119568	9360	90499412
Arterial haemorrhage	134.44	10.36	66	119609	2457	90506315
Ill-defined disorder	133.79	10.36	39	119636	184852	90323920
Joint range of motion decreased	132.13	10.36	13	119662	135630	90373142
Melaena	130.02	10.36	193	119482	34604	90474168
Psoriasis	127.43	10.36	21	119654	147733	90361039
Hypovolaemic shock	125.29	10.36	91	119584	7003	90501769
Fatigue	121.63	10.36	960	118715	1153063	89355709
Computerised tomogram thorax abnormal	121.48	10.36	58	119617	2029	90506743
Haemoperitoneum	118.97	10.36	68	119607	3460	90505312
Pancytopenia	117.63	10.36	388	119287	119875	90388897
Respiratory failure	116.68	10.36	383	119292	118035	90390737
Bursitis	112.89	10.36	19	119656	131635	90377137
Pleural effusion	112.85	10.36	365	119310	111626	90397146
Hyperkalaemia	112.00	10.36	258	119417	64706	90444066
Renal failure	110.18	10.36	402	119273	130605	90378167
Grip strength decreased	108.18	10.36	3	119672	92573	90416199
Intra-abdominal haemorrhage	108.12	10.36	58	119617	2604	90506168
Lower respiratory tract infection	106.81	10.36	104	119571	250555	90258217
Oliguria	106.56	10.36	98	119577	10526	90498246
Blister	105.00	10.36	109	119566	254889	90253883
Maternal exposure during pregnancy	104.52	10.36	823	118852	359240	90149532
Leukopenia	103.98	10.36	331	119344	100379	90408393
Loss of personal independence in daily activities	103.56	10.36	26	119649	136079	90372693
Hyponatraemia	103.35	10.36	399	119276	133139	90375633
Hypercholesterolaemia	100.04	10.36	9	119666	100883	90407889
Facet joint syndrome	99.69	10.36	8	119667	98381	90410391
Product use issue	99.51	10.36	177	119498	329742	90179030
Musculoskeletal pain	99.31	10.36	51	119624	171200	90337572
Gamma-glutamyltransferase increased	99.06	10.36	179	119496	37773	90470999
Subdural haematoma	98.98	10.36	116	119559	16529	90492243
Pyrexia	98.36	10.36	1316	118359	659169	89849603
Transaminases increased	97.82	10.36	176	119499	37016	90471756
Atrial fibrillation	97.57	10.36	392	119283	133219	90375553
Cytokine release syndrome	97.20	10.36	150	119525	27823	90480949
Impaired healing	96.54	10.36	100	119575	234099	90274673
Peripheral swelling	96.19	10.36	256	119419	412850	90095922
Insomnia	95.19	10.36	185	119490	333289	90175483
Computerised tomogram thorax	95.17	10.36	33	119642	492	90508280
Intentional product use issue	94.72	10.36	88	119587	216804	90291968
Ovarian hyperstimulation syndrome	91.90	10.36	70	119605	5792	90502980
Osteoarthritis	90.81	10.36	75	119600	195655	90313117
Migraine	90.78	10.36	71	119604	190321	90318451
Atelectasis	89.21	10.36	134	119541	24275	90484497
Tachycardia	87.38	10.36	426	119249	157247	90351525
Sleep disorder	86.88	10.36	80	119595	197950	90310822
Hypoaesthesia	85.67	10.36	179	119496	314031	90194741
Depression	85.58	10.36	167	119508	300434	90208338
Road traffic accident	84.95	10.36	19	119656	107607	90401165
Compartment syndrome	84.69	10.36	51	119624	2861	90505911
Vascular device infection	84.23	10.36	91	119584	11861	90496911
Extradural haematoma	83.83	10.36	45	119630	2023	90506749
Gastrointestinal disorder	83.60	10.36	131	119544	256556	90252216
Dry mouth	83.58	10.36	72	119603	183987	90324785
Septic shock	82.70	10.36	272	119403	83888	90424884
Haemorrhage intracranial	82.50	10.36	101	119574	15061	90493711
Spontaneous haematoma	82.42	10.36	37	119638	1121	90507651
Labelled drug-drug interaction medication error	82.38	10.36	99	119576	14483	90494289
Hepatitis acute	82.23	10.36	86	119589	10801	90497971
Ecchymosis	81.94	10.36	91	119584	12232	90496540
Prescribed overdose	81.70	10.36	15	119660	97610	90411162
Haemarthrosis	81.59	10.36	56	119619	3938	90504834
Arthritis	81.54	10.36	61	119614	167254	90341518
Autoimmune disorder	81.33	10.36	5	119670	76739	90432033
Abortion induced	81.14	10.36	89	119586	11799	90496973
Coagulopathy	81.08	10.36	125	119550	23164	90485608
Malaise	80.86	10.36	449	119226	585537	89923235
Alanine aminotransferase increased	80.72	10.36	340	119335	117998	90390774
Product dose omission issue	80.50	10.36	165	119510	291522	90217250
Memory impairment	80.41	10.36	85	119590	197159	90311613
Multiple organ dysfunction syndrome	80.25	10.36	235	119440	68101	90440671
Hepatitis cholestatic	80.14	10.36	76	119599	8485	90500287
Wound infection pseudomonas	79.16	10.36	43	119632	1980	90506792
Lymphopenia	78.53	10.36	122	119553	22759	90486013
Post procedural haemorrhage	78.38	10.36	76	119599	8722	90500050
Purpura	78.09	10.36	97	119578	14681	90494091
Injection site haematoma	77.62	10.36	68	119607	6854	90501918
Cardiac arrest	77.50	10.36	309	119366	104626	90404146
Cholestatic liver injury	77.00	10.36	53	119622	3744	90505028
Thrombocytosis	76.95	10.36	68	119607	6933	90501839
Rash morbilliform	76.47	10.36	54	119621	3975	90504797
Liver injury	75.90	10.36	68	119607	170499	90338273
Ischaemic stroke	75.81	10.36	118	119557	22048	90486724
Tachyarrhythmia	74.88	10.36	60	119615	5346	90503426
Spinal epidural haematoma	74.39	10.36	36	119639	1298	90507474
Lymphatic fistula	74.22	10.36	37	119638	1424	90507348
Urticaria	74.12	10.36	192	119483	312542	90196230
Deep vein thrombosis postoperative	73.89	10.36	5	119670	70804	90437968
Night sweats	73.68	10.36	39	119636	128727	90380045
Aspartate aminotransferase increased	73.54	10.36	300	119375	102637	90406135
Haematemesis	73.12	10.36	147	119528	33579	90475193
Femoral hernia incarcerated	73.12	10.36	37	119638	1471	90507301
Paraplegia	72.45	10.36	49	119626	3363	90505409
Cardiogenic shock	72.44	10.36	122	119553	24346	90484426
Seroma	72.37	10.36	47	119628	3013	90505759
Injury	71.89	10.36	93	119582	197256	90311516
Aplastic anaemia	71.57	10.36	88	119587	13181	90495591
Activated partial thromboplastin time prolonged	70.47	10.36	68	119607	7757	90501015
Adverse drug reaction	70.31	10.36	33	119642	116668	90392104
Blood loss anaemia	69.36	10.36	76	119599	10064	90498708
Electrocardiogram QT prolonged	68.36	10.36	231	119444	72225	90436547
Spinal cord haematoma	68.18	10.36	21	119654	210	90508562
Dizziness	67.60	10.36	478	119197	588806	89919966
Faecaloma	67.59	10.36	76	119599	10355	90498417
Post procedural haematoma	67.51	10.36	34	119641	1338	90507434
Pancreatic steatosis	67.32	10.36	36	119639	1606	90507166
Sciatica	66.97	10.36	25	119650	101357	90407415
Dermatitis bullous	66.57	10.36	75	119600	10241	90498531
Anuria	65.40	10.36	89	119586	14729	90494043
Acute respiratory failure	64.87	10.36	162	119513	42756	90466016
Embolism	64.75	10.36	71	119604	9410	90499362
International normalised ratio decreased	64.52	10.36	52	119623	4672	90504100
Blood alkaline phosphatase increased	63.96	10.36	173	119502	47906	90460866
Adverse event	63.67	10.36	38	119637	117380	90391392
Hyperglycaemia	63.45	10.36	179	119496	50791	90457981
Gait inability	63.25	10.36	60	119615	146396	90362376
Epistaxis	63.12	10.36	251	119424	84874	90423898
Syncope	62.76	10.36	343	119332	132320	90376452
Encephalopathy	62.67	10.36	168	119507	46276	90462496
Inflammation	62.17	10.36	87	119588	178505	90330267
Peripheral venous disease	61.99	10.36	17	119658	83904	90424868
Hypercoagulation	61.95	10.36	38	119637	2204	90506568
Adrenal haemorrhage	61.76	10.36	24	119651	501	90508271
Muscle spasms	61.72	10.36	152	119523	251731	90257041
Cardio-respiratory arrest	61.07	10.36	203	119472	62937	90445835
Pulmonary fibrosis	60.86	10.36	33	119642	107470	90401302
Blepharospasm	60.65	10.36	3	119672	55442	90453330
Sinus bradycardia	60.44	10.36	92	119583	16860	90491912
Abortion spontaneous	59.78	10.36	182	119493	53874	90454898
Caesarean section	59.54	10.36	96	119579	18481	90490291
Wound dehiscence	58.96	10.36	54	119621	5768	90503004
Toxic epidermal necrolysis	58.06	10.36	131	119544	32397	90476375
Bradycardia	58.02	10.36	242	119433	83605	90425167
Respiratory distress	57.81	10.36	146	119529	38800	90469972
Haemorrhagic stroke	57.65	10.36	56	119619	6440	90502332
Pulmonary hypertension	57.56	10.36	154	119521	42369	90466403
Haemoptysis	57.05	10.36	132	119543	33188	90475584
Wound infection	56.90	10.36	35	119640	106367	90402405
Device related infection	56.63	10.36	113	119562	25673	90483099
Vaginal haemorrhage	55.89	10.36	126	119549	31145	90477627
Vascular pseudoaneurysm	54.88	10.36	32	119643	1691	90507081
Haemodynamic instability	54.09	10.36	72	119603	11667	90497105
Abdominal pain upper	53.77	10.36	241	119434	332433	90176339
Cell death	53.52	10.36	39	119636	3016	90505756
Red blood cell sedimentation rate increased	53.50	10.36	21	119654	82574	90426198
Lower limb fracture	52.83	10.36	23	119652	84990	90423782
Clostridium difficile colitis	52.72	10.36	112	119563	26594	90482178
Amnesia	52.29	10.36	40	119635	108465	90400307
Escherichia infection	52.12	10.36	83	119592	15812	90492960
Sinobronchitis	51.82	10.36	23	119652	678	90508094
Nail disorder	51.80	10.36	8	119667	59059	90449713
Ear infection	51.78	10.36	14	119661	69761	90439011
Laryngitis	51.76	10.36	4	119671	50749	90458023
Hip arthroplasty	51.68	10.36	18	119657	76190	90432582
Alveolitis	51.65	10.36	38	119637	2983	90505789
Aortic arteriosclerosis	51.53	10.36	57	119618	7627	90501145
Prothrombin time prolonged	51.40	10.36	64	119611	9708	90499064
Bullous haemorrhagic dermatosis	50.88	10.36	17	119658	225	90508547
Infection	50.65	10.36	276	119399	361818	90146954
Erysipelas	50.39	10.36	61	119614	8991	90499781
Groin pain	50.37	10.36	71	119604	12142	90496630
COVID-19 pneumonia	50.35	10.36	88	119587	18089	90490683
Petechiae	49.98	10.36	81	119594	15660	90493112
Cerebral haematoma	49.84	10.36	43	119632	4246	90504526
Circulatory collapse	49.80	10.36	105	119570	24799	90483973
Subcutaneous haematoma	49.71	10.36	31	119644	1852	90506920
Rash	49.41	10.36	747	118928	795353	89713419
Dermatitis exfoliative generalised	49.23	10.36	48	119627	5545	90503227
Feeling abnormal	49.23	10.36	91	119584	167144	90341628
Fibrin D dimer increased	48.33	10.36	47	119628	5413	90503359
Jugular vein thrombosis	48.02	10.36	39	119636	3542	90505230
Inflammatory marker increased	47.91	10.36	60	119615	9154	90499618
Placental insufficiency	47.85	10.36	29	119646	1646	90507126
Cerebral venous sinus thrombosis	47.79	10.36	33	119642	2343	90506429
Venous thrombosis	47.77	10.36	47	119628	5490	90503282
Epidural haemorrhage	46.55	10.36	17	119658	297	90508475
Blood creatinine increased	46.52	10.36	260	119415	101126	90407646
Aortic valve stenosis	46.24	10.36	41	119634	4199	90504573
Upper gastrointestinal haemorrhage	46.10	10.36	97	119578	22879	90485893
Needle issue	46.02	10.36	73	119602	13861	90494911
Truncus arteriosus persistent	46.00	10.36	18	119657	383	90508389
Peritoneal haematoma	45.93	10.36	13	119662	94	90508678
Joint stiffness	45.59	10.36	23	119652	78019	90430753
Stevens-Johnson syndrome	45.57	10.36	112	119563	29264	90479508
Dehydration	45.55	10.36	424	119251	194023	90314749
Thrombophlebitis	45.46	10.36	43	119632	4785	90503987
Premature labour	45.45	10.36	71	119604	13305	90495467
Pre-eclampsia	45.23	10.36	64	119611	10984	90497788
Pain in extremity	45.23	10.36	379	119296	450150	90058622
Postpartum haemorrhage	45.15	10.36	32	119643	2369	90506403
Gastrooesophageal reflux disease	45.09	10.36	95	119580	166242	90342530
Tricuspid valve incompetence	45.05	10.36	80	119595	16651	90492121
Hepatic cirrhosis	44.54	10.36	14	119661	63239	90445533
Haematocrit decreased	44.54	10.36	139	119536	41693	90467079
Sleep disorder due to a general medical condition	44.32	10.36	4	119671	44734	90464038
Lupus-like syndrome	44.27	10.36	6	119669	48840	90459932
Syringe issue	44.24	10.36	39	119636	3963	90504809
COVID-19 treatment	43.93	10.36	13	119662	112	90508660
Haemorrhagic transformation stroke	43.70	10.36	25	119650	1274	90507498
Spinal epidural haemorrhage	43.52	10.36	16	119659	285	90508487
Blood pressure increased	43.02	10.36	126	119549	197091	90311681
Drug abuse	42.78	10.36	28	119647	82319	90426453
Hypernatraemia	42.37	10.36	57	119618	9330	90499442
Ascites	42.24	10.36	149	119526	47591	90461181
Metabolic acidosis	41.94	10.36	165	119510	55511	90453261
Cardiac valve replacement complication	41.68	10.36	13	119662	136	90508636
Back injury	41.61	10.36	6	119669	46616	90462156
Intentional overdose	41.03	10.36	38	119637	93796	90414976
Foetal death	41.01	10.36	87	119588	20636	90488136
Taste disorder	40.94	10.36	15	119660	61531	90447241
Intentional product misuse	40.72	10.36	35	119640	89569	90419203
Condition aggravated	40.71	10.36	548	119127	594997	89913775
Exostosis	40.70	10.36	10	119665	53124	90455648
Diverticulum intestinal	40.48	10.36	55	119620	9087	90499685
Toxicity to various agents	40.46	10.36	219	119456	287627	90221145
Small for dates baby	40.43	10.36	41	119634	4966	90503806
Weight decreased	40.23	10.36	315	119360	379595	90129177
Coagulation time prolonged	40.07	10.36	26	119649	1664	90507108
Pneumonitis	40.06	10.36	139	119536	44031	90464741
Patent ductus arteriosus	39.82	10.36	39	119636	4530	90504242
Knee arthroplasty	39.65	10.36	31	119644	83151	90425621
Therapeutic response decreased	39.63	10.36	36	119639	89693	90419079
Device expulsion	39.59	10.36	4	119671	40882	90467890
Hepatic cyst	39.43	10.36	46	119629	6522	90502250
Chest wall haematoma	39.41	10.36	14	119661	225	90508547
Frequent bowel movements	39.38	10.36	13	119662	56922	90451850
Polyneuropathy	39.21	10.36	82	119593	19259	90489513
Pulmonary thrombosis	39.07	10.36	56	119619	9726	90499046
Congenital cardiovascular anomaly	38.95	10.36	17	119658	481	90508291
Erythema multiforme	38.86	10.36	63	119612	12183	90496589
Cystitis radiation	38.81	10.36	11	119664	80	90508692
Anticoagulation drug level below therapeutic	38.58	10.36	19	119656	712	90508060
Nail bed inflammation	38.57	10.36	26	119649	1775	90506997
Hypertension	38.57	10.36	402	119273	457130	90051642
Peripheral nerve injury	38.39	10.36	19	119656	720	90508052
Mitral valve incompetence	38.31	10.36	89	119586	22435	90486337
Rash pustular	38.06	10.36	50	119625	7999	90500773
Pseudomonal sepsis	38.02	10.36	37	119638	4265	90504507
Malnutrition	37.99	10.36	79	119596	18479	90490293
Therapy non-responder	37.96	10.36	77	119598	136627	90372145
Streptococcal sepsis	37.78	10.36	34	119641	3550	90505222
Disorientation	37.59	10.36	136	119539	43978	90464794
Plasma cell myeloma	37.48	10.36	129	119546	40699	90468073
Myocardial infarction	37.41	10.36	254	119421	105718	90403054
Excessive eye blinking	37.26	10.36	23	119652	1349	90507423
Inappropriate schedule of product administration	37.08	10.36	90	119585	149843	90358929
Gait disturbance	36.71	10.36	198	119477	260298	90248474
Premature separation of placenta	36.57	10.36	28	119647	2334	90506438
Anxiety	36.56	10.36	249	119426	309523	90199249
Hypochromic anaemia	36.42	10.36	27	119648	2144	90506628
Blood pressure fluctuation	36.20	10.36	12	119663	52401	90456371
Tachypnoea	36.02	10.36	84	119591	21225	90487547
Device safety feature issue	35.69	10.36	14	119661	300	90508472
Nasal mucosal disorder	35.50	10.36	25	119650	1832	90506940
Onychomycosis	35.31	10.36	4	119671	37372	90471400
Ear pain	35.24	10.36	16	119659	57686	90451086
Obesity	35.13	10.36	53	119622	105454	90403318
Protein total decreased	35.02	10.36	45	119630	7044	90501728
Illness	34.89	10.36	34	119641	81935	90426837
Intracranial pressure increased	34.86	10.36	44	119631	6767	90502005
HELLP syndrome	34.58	10.36	21	119654	1196	90507576
Cardiac septal defect	34.42	10.36	18	119657	767	90508005
Hypertransaminasaemia	34.33	10.36	69	119606	15756	90493016
Cerebral haemorrhage foetal	34.29	10.36	14	119661	334	90508438
Acute respiratory distress syndrome	34.01	10.36	99	119576	28587	90480185
Leukocytosis	33.94	10.36	104	119571	30886	90477886
Nasal congestion	33.91	10.36	36	119639	83378	90425394
Spinal cord haemorrhage	33.79	10.36	13	119662	264	90508508
Pulmonary haemorrhage	33.67	10.36	47	119628	7966	90500806
Soft tissue infection	33.57	10.36	29	119646	2868	90505904
Symmetrical drug-related intertriginous and flexural exanthema	33.36	10.36	19	119656	960	90507812
Bladder tamponade	32.96	10.36	11	119664	145	90508627
Device related sepsis	32.91	10.36	36	119639	4757	90504015
Blood bilirubin increased	32.88	10.36	129	119546	43341	90465431
Product prescribing error	32.86	10.36	101	119574	30044	90478728
Foot deformity	32.77	10.36	19	119656	59632	90449140
Cardiac failure	32.63	10.36	252	119423	109244	90399528
Hepatic failure	32.60	10.36	121	119554	39607	90469165
Duodenal ulcer haemorrhage	32.52	10.36	27	119648	2529	90506243
Vitamin K deficiency	32.37	10.36	15	119660	490	90508282
Liver disorder	32.24	10.36	70	119605	121199	90387573
Disseminated intravascular coagulation	32.23	10.36	81	119594	21457	90487315
International normalised ratio abnormal	31.99	10.36	32	119643	3813	90504959
Left ventricular dysfunction	31.87	10.36	64	119611	14605	90494167
Haemothorax	31.72	10.36	26	119649	2392	90506380
Metastases to central nervous system	31.70	10.36	71	119604	17471	90491301
Neutropenic sepsis	31.23	10.36	72	119603	18058	90490714
Erythrodermic psoriasis	31.21	10.36	19	119656	1087	90507685
Electrocardiogram ST segment elevation	30.82	10.36	32	119643	3984	90504788
Rectal haemorrhage	30.82	10.36	201	119474	82543	90426229
Peptic ulcer perforation	30.59	10.36	14	119661	444	90508328
Fluid retention	30.55	10.36	43	119632	88048	90420724
Vena cava thrombosis	30.50	10.36	26	119649	2526	90506246
Systolic dysfunction	30.43	10.36	23	119652	1881	90506891
Haemolytic anaemia	30.30	10.36	55	119620	11642	90497130
Urinary tract infection	30.15	10.36	569	119106	305063	90203709
Neonatal gastrointestinal disorder	30.06	10.36	9	119666	81	90508691
Dyspepsia	29.96	10.36	147	119528	198013	90310759
Neonatal respiratory distress syndrome	29.93	10.36	28	119647	3073	90505699
Hypersensitivity myocarditis	29.88	10.36	12	119663	274	90508498
Rhinorrhoea	29.76	10.36	44	119631	88272	90420500
Procedural haemorrhage	29.75	10.36	28	119647	3096	90505676
Cerebral artery occlusion	29.39	10.36	18	119657	1041	90507731
Influenza like illness	29.32	10.36	38	119637	80573	90428199
Antiphospholipid syndrome	28.89	10.36	24	119651	2250	90506522
Brain oedema	28.81	10.36	68	119607	17317	90491455
Disability	28.72	10.36	9	119666	40736	90468036
Cardiovascular disorder	28.28	10.36	58	119617	13434	90495338
Shock	28.25	10.36	93	119582	28685	90480087
Product quality issue	28.24	10.36	38	119637	79287	90429485
Right ventricular dilatation	28.21	10.36	21	119654	1678	90507094
Administration site necrosis	28.16	10.36	5	119670	0	90508772
Abdominal wall haemorrhage	28.02	10.36	10	119665	163	90508609
Stress	27.96	10.36	40	119635	81355	90427417
Toxic encephalopathy	27.94	10.36	45	119630	8654	90500118
Autoimmune heparin-induced thrombocytopenia	27.92	10.36	6	119669	10	90508762
Brain herniation	27.90	10.36	31	119644	4169	90504603
Schizencephaly	27.78	10.36	12	119663	331	90508441
Neuromyotonia	27.67	10.36	8	119667	63	90508709
Transfusion	27.47	10.36	67	119608	17421	90491351
Hemianopia homonymous	27.38	10.36	16	119659	849	90507923
Escherichia sepsis	27.30	10.36	36	119639	5780	90502992
Cataract	27.25	10.36	33	119642	72059	90436713
Intraventricular haemorrhage	27.17	10.36	24	119651	2445	90506327
Foetal monitoring abnormal	27.16	10.36	11	119664	257	90508515
Protein deficiency	27.16	10.36	12	119663	350	90508422
Congenital central nervous system anomaly	27.06	10.36	13	119662	461	90508311
Hyperleukocytosis	27.00	10.36	16	119659	871	90507901
Dysaesthesia	26.97	10.36	34	119641	5221	90503551
Target skin lesion	26.94	10.36	9	119666	119	90508653
Large intestine perforation	26.87	10.36	47	119628	9665	90499107
Neonatal respiratory depression	26.80	10.36	10	119665	186	90508586
Oedema	26.71	10.36	155	119520	200140	90308632
Basal ganglion degeneration	26.54	10.36	12	119663	370	90508402
Product administered at inappropriate site	26.48	10.36	30	119645	4121	90504651
Gestational diabetes	26.46	10.36	49	119626	10533	90498239
Subarachnoid haemorrhage	26.44	10.36	67	119608	17837	90490935
Paraesthesia	26.27	10.36	208	119467	250118	90258654
Postoperative wound infection	26.14	10.36	56	119619	13370	90495402
Vision blurred	25.88	10.36	68	119607	110225	90398547
Small intestinal obstruction	25.86	10.36	74	119601	21160	90487612
Hyperbilirubinaemia	25.85	10.36	57	119618	13879	90494893
Foetal heart rate abnormal	25.80	10.36	16	119659	946	90507826
Disease progression	25.68	10.36	318	119357	156297	90352475
Prescribed underdose	25.64	10.36	37	119638	74982	90433790
Purple glove syndrome	25.59	10.36	10	119665	212	90508560
Haemorrhage in pregnancy	25.58	10.36	22	119653	2163	90506609
Neck pain	25.43	10.36	72	119603	113891	90394881
Aphasia	25.38	10.36	118	119557	42694	90466078
Urinary retention	25.37	10.36	108	119567	37636	90471136
Necrosis	25.17	10.36	37	119638	6573	90502199
Factor XIII deficiency	25.12	10.36	8	119667	90	90508682
Liver function test abnormal	25.07	10.36	133	119542	50712	90458060
Generalised oedema	24.78	10.36	68	119607	18985	90489787
Walking aid user	24.75	10.36	8	119667	35498	90473274
Gastritis	24.69	10.36	115	119560	41638	90467134
Suicidal ideation	24.68	10.36	37	119638	73818	90434954
Ventricular septal defect	24.66	10.36	33	119642	5374	90503398
Acidosis	24.66	10.36	53	119622	12683	90496089
Protein S deficiency	24.57	10.36	6	119669	22	90508750
Febrile infection	24.56	10.36	21	119654	2048	90506724
Lower gastrointestinal haemorrhage	24.56	10.36	43	119632	8849	90499923
Muscular weakness	24.43	10.36	166	119509	206500	90302272
Cerebrovascular accident	24.37	10.36	260	119415	123273	90385499
Heart disease congenital	24.34	10.36	19	119656	1630	90507142
Product monitoring error	24.28	10.36	30	119645	4514	90504258
Heparin-induced thrombocytopenia test	24.22	10.36	5	119670	6	90508766
Vaccination site reaction	24.17	10.36	10	119665	247	90508525
Oligohydramnios	24.16	10.36	38	119637	7163	90501609
Ejection fraction decreased	24.14	10.36	83	119592	26170	90482602
Localised oedema	24.06	10.36	35	119640	6159	90502613
Suicide attempt	24.03	10.36	39	119636	75360	90433412
Therapeutic embolisation	24.02	10.36	10	119665	251	90508521
Hypoalbuminaemia	24.01	10.36	60	119615	15837	90492935
Incubator therapy	24.00	10.36	7	119668	57	90508715
Generalised bullous fixed drug eruption	23.95	10.36	11	119664	352	90508420
Blood albumin decreased	23.90	10.36	62	119613	16741	90492031
Urine output decreased	23.89	10.36	52	119623	12551	90496221
Blood lactate dehydrogenase increased	23.86	10.36	82	119593	25850	90482922
Infantile apnoea	23.85	10.36	17	119658	1270	90507502
Arrhythmogenic right ventricular dysplasia	23.78	10.36	6	119669	26	90508746
Developmental glaucoma	23.69	10.36	7	119668	60	90508712
Coronary artery thrombosis	23.30	10.36	16	119659	1126	90507646
Phlebitis	23.27	10.36	38	119637	7392	90501380
Gastric haemorrhage	23.16	10.36	37	119638	7066	90501706
Eye pruritus	23.15	10.36	5	119670	29022	90479750
Nonreassuring foetal heart rate pattern	23.09	10.36	7	119668	66	90508706
Myelosuppression	23.07	10.36	22	119653	53569	90455203
Eructation	23.07	10.36	47	119628	10835	90497937
Anticoagulation drug level above therapeutic	22.94	10.36	20	119655	2002	90506770
Electrocardiogram repolarisation abnormality	22.83	10.36	17	119658	1359	90507413
Type IV hypersensitivity reaction	22.74	10.36	27	119648	3899	90504873
Systemic inflammatory response syndrome	22.72	10.36	35	119640	6481	90502291
Injection site bruising	22.58	10.36	132	119543	52175	90456597
Candida infection	22.54	10.36	97	119578	33960	90474812
Upper respiratory tract infection	22.53	10.36	90	119585	128228	90380544
Exposure via blood	22.52	10.36	4	119671	0	90508772
Pruritus	22.45	10.36	544	119131	540981	89967791
Adrenal cortex necrosis	22.35	10.36	5	119670	11	90508761
Foetal arrhythmia	22.31	10.36	9	119666	208	90508564
Intracardiac thrombus	22.08	10.36	21	119654	2353	90506419
Renal tubular necrosis	22.05	10.36	55	119620	14500	90494272
Immunodeficiency	22.05	10.36	15	119660	43219	90465553
Pathological fracture	22.01	10.36	43	119632	9617	90499155
Supraventricular tachycardia	21.94	10.36	59	119616	16277	90492495
Influenza	21.81	10.36	102	119573	139162	90369610
Abdominal pain	21.75	10.36	680	118995	395041	90113731
Hepatitis	21.74	10.36	164	119511	70575	90438197
Device malfunction	21.68	10.36	69	119606	20908	90487864
Eye irritation	21.42	10.36	9	119666	33969	90474803
Anaesthesia	21.38	10.36	11	119664	453	90508319
Acute myocardial infarction	21.30	10.36	97	119578	34793	90473979
Vascular stent thrombosis	21.28	10.36	15	119660	1101	90507671
Blood urea increased	21.20	10.36	88	119587	30325	90478447
Varicose vein	20.98	10.36	36	119639	7291	90501481
Bronchopulmonary dysplasia	20.97	10.36	12	119663	612	90508160
Injection site swelling	20.96	10.36	29	119646	59810	90448962
Post procedural complication	20.94	10.36	64	119611	18978	90489794
Heparin-induced thrombocytopenia test positive	20.77	10.36	5	119670	17	90508755
Epidural analgesia	20.77	10.36	8	119667	163	90508609
Otitis media acute	20.68	10.36	15	119660	1152	90507620
Injection site reaction	20.68	10.36	58	119617	92022	90416750
Intra-abdominal fluid collection	20.65	10.36	22	119653	2822	90505950
Impaired quality of life	20.60	10.36	3	119672	23141	90485631
Skin necrosis	20.59	10.36	59	119616	16882	90491890
Neonatal infection	20.48	10.36	9	119666	259	90508513
Sneezing	20.34	10.36	7	119668	29862	90478910
Urosepsis	20.29	10.36	68	119607	21164	90487608
Microembolism	20.29	10.36	4	119671	3	90508769
Jaundice neonatal	20.25	10.36	14	119661	996	90507776
Injection site erythema	20.00	10.36	65	119610	98437	90410335
Hepatic infarction	19.91	10.36	12	119663	674	90508098
Coma	19.91	10.36	164	119511	72468	90436304
Brain compression	19.91	10.36	11	119664	524	90508248
Enterococcal infection	19.83	10.36	42	119633	9949	90498823
Twin pregnancy	19.83	10.36	15	119660	1228	90507544
Adrenal haematoma	19.75	10.36	5	119670	22	90508750
Intestinal ischaemia	19.59	10.36	39	119636	8844	90499928
Visual impairment	19.54	10.36	99	119576	132266	90376506
Hip fracture	19.48	10.36	91	119584	32986	90475786
Platelet count decreased	19.48	10.36	271	119404	136698	90372074
Spinal cord compression	19.44	10.36	28	119647	4883	90503889
Hepatitis fulminant	19.42	10.36	25	119650	3920	90504852
Crystalluria	19.40	10.36	11	119664	551	90508221
Vascular purpura	19.34	10.36	17	119658	1721	90507051
Neutrophil count increased	19.33	10.36	63	119612	19327	90489445
Skin candida	19.31	10.36	17	119658	1724	90507048
Pericardial effusion	19.30	10.36	98	119577	36735	90472037
Back disorder	19.29	10.36	5	119670	25626	90483146
Pleural neoplasm	19.23	10.36	10	119665	421	90508351
Blood phosphorus increased	19.15	10.36	26	119649	4292	90504480
Splenic injury	19.03	10.36	8	119667	206	90508566
Purpura non-thrombocytopenic	19.02	10.36	7	119668	125	90508647
Defaecation disorder	18.92	10.36	13	119662	916	90507856
Metastases to meninges	18.91	10.36	24	119651	3711	90505061
Breast haematoma	18.89	10.36	8	119667	210	90508562
Gastrointestinal ulcer haemorrhage	18.80	10.36	13	119662	925	90507847
Uterine enlargement	18.75	10.36	15	119660	1333	90507439
Thymus disorder	18.69	10.36	9	119666	321	90508451
Myocarditis	18.68	10.36	50	119625	13756	90495016
Cachexia	18.66	10.36	33	119642	6845	90501927
Neurological decompensation	18.53	10.36	23	119652	3478	90505294
Adverse reaction	18.52	10.36	8	119667	29704	90479068
Oesophageal compression	18.49	10.36	4	119671	7	90508765
Abdominal mass	18.42	10.36	23	119652	3498	90505274
Language disorder	18.35	10.36	20	119655	2632	90506140
Bronchial aspiration procedure	18.31	10.36	8	119667	227	90508545
Splenic infarction	18.25	10.36	18	119657	2109	90506663
Ulcer haemorrhage	18.22	10.36	6	119669	26315	90482457
Blood creatine phosphokinase increased	18.17	10.36	91	119584	33932	90474840
Factor Xa activity increased	18.14	10.36	4	119671	8	90508764
Nail avulsion	18.14	10.36	9	119666	343	90508429
Therapeutic response shortened	18.13	10.36	4	119671	22875	90485897
Paranasal sinus inflammation	18.09	10.36	11	119664	628	90508144
Hypercapnia	18.07	10.36	32	119643	6645	90502127
Central nervous system injury	18.02	10.36	7	119668	146	90508626
Spinal subdural haematoma	17.97	10.36	7	119668	147	90508625
Duodenal polyp	17.93	10.36	8	119667	239	90508533
Contusion	17.91	10.36	229	119446	250987	90257785
Cerebral artery embolism	17.90	10.36	13	119662	1000	90507772
Scintillating scotoma	17.89	10.36	7	119668	149	90508623
Pulmonary alveolar haemorrhage	17.88	10.36	30	119645	5968	90502804
Pharyngeal haemorrhage	17.82	10.36	11	119664	645	90508127
Antithrombin III deficiency	17.82	10.36	4	119671	9	90508763
Sinus congestion	17.71	10.36	7	119668	27417	90481355
Peripheral artery thrombosis	17.67	10.36	18	119657	2192	90506580
Ventricular hypokinesia	17.66	10.36	28	119647	5313	90503459
Unresponsive to stimuli	17.64	10.36	98	119577	38023	90470749
Bradypnoea	17.63	10.36	26	119649	4632	90504140
Cutaneous vasculitis	17.60	10.36	33	119642	7160	90501612
Polyserositis	17.56	10.36	11	119664	662	90508110
Streptococcal bacteraemia	17.55	10.36	18	119657	2209	90506563
Vessel puncture site haematoma	17.55	10.36	7	119668	157	90508615
Polyhydramnios	17.51	10.36	19	119656	2489	90506283
Face oedema	17.47	10.36	69	119606	23249	90485523
Ultrasound Doppler abnormal	17.47	10.36	7	119668	159	90508613
Radiation fibrosis	17.45	10.36	5	119670	38	90508734
Hepatitis toxic	17.40	10.36	23	119652	3702	90505070
Osteoporosis	17.39	10.36	67	119608	96464	90412308
Blood pressure decreased	17.36	10.36	163	119512	74732	90434040
Peripheral sensory neuropathy	17.35	10.36	38	119637	9212	90499560
Pelvic venous thrombosis	17.29	10.36	17	119658	1984	90506788
Congenital clavicular agenesis	17.27	10.36	6	119669	90	90508682
Epstein-Barr virus test positive	17.15	10.36	11	119664	690	90508082
Carcinoembryonic antigen	17.15	10.36	6	119669	92	90508680
Microphthalmos	17.07	10.36	7	119668	169	90508603
Empyema	17.07	10.36	18	119657	2282	90506490
Dyspnoea	17.05	10.36	1367	118308	879588	89629184
Staphylococcal infection	17.03	10.36	116	119559	48323	90460449
Maternal drugs affecting foetus	17.01	10.36	27	119648	5128	90503644
Anti factor X antibody positive	16.89	10.36	3	119672	0	90508772
Bacterascites	16.89	10.36	3	119672	0	90508772
Abdominal wall oedema	16.89	10.36	3	119672	0	90508772
Skin neoplasm bleeding	16.89	10.36	3	119672	0	90508772
Cerebral venous thrombosis	16.89	10.36	18	119657	2310	90506462
Erythema	16.84	10.36	409	119266	228837	90279935
Carbohydrate antigen 15-3	16.80	10.36	6	119669	98	90508674
Rash erythematous	16.78	10.36	145	119530	64959	90443813
Klebsiella infection	16.76	10.36	40	119635	10257	90498515
Hygroma colli	16.75	10.36	4	119671	13	90508759
Necrotising colitis	16.75	10.36	14	119661	1324	90507448
Bacteraemia	16.72	10.36	66	119609	22234	90486538
Metabolic alkalosis	16.71	10.36	22	119653	3527	90505245
Lice infestation	16.70	10.36	8	119667	282	90508490
Jaundice	16.68	10.36	86	119589	32431	90476341
Throat irritation	16.66	10.36	24	119651	48671	90460101
Loss of consciousness	16.65	10.36	269	119406	139969	90368803
Coronary artery disease	16.61	10.36	88	119587	33535	90475237
Hiatus hernia	16.61	10.36	72	119603	25289	90483483
Pancreatitis acute	16.52	10.36	85	119590	32030	90476742
Subclavian vein thrombosis	16.49	10.36	17	119658	2099	90506673
Peripheral ischaemia	16.43	10.36	28	119647	5639	90503133
Alkalosis	16.40	10.36	10	119665	574	90508198
Embolism venous	16.37	10.36	22	119653	3598	90505174
Dandy-Walker syndrome	16.26	10.36	6	119669	108	90508664
Pneumothorax	16.25	10.36	59	119616	19108	90489664
Sinus disorder	16.21	10.36	13	119662	34434	90474338
Decubitus ulcer	16.20	10.36	43	119632	11770	90497002
Escherichia bacteraemia	16.19	10.36	28	119647	5707	90503065
Right ventricular failure	16.18	10.36	59	119616	19146	90489626
Hiatus hernia strangulated	16.14	10.36	8	119667	304	90508468
Respiratory tract congestion	16.12	10.36	8	119667	27402	90481370
Cerebellar haemorrhage	16.10	10.36	15	119660	1638	90507134
Placental infarction	16.09	10.36	8	119667	306	90508466
Blood pressure systolic increased	16.07	10.36	33	119642	58312	90450460
Breast cancer	16.04	10.36	29	119646	53732	90455040
Coronary artery embolism	16.01	10.36	7	119668	199	90508573
Eczema	15.92	10.36	122	119553	52748	90456024
Stoma site candida	15.91	10.36	4	119671	17	90508755
Talipes	15.89	10.36	15	119660	1665	90507107
Blood creatine increased	15.86	10.36	31	119644	6936	90501836
Femoral neck fracture	15.85	10.36	39	119636	10194	90498578
Stupor	15.78	10.36	27	119648	5455	90503317
Necrotising panniculitis	15.73	10.36	4	119671	18	90508754
Multiple lentigines syndrome	15.72	10.36	7	119668	208	90508564
Lymphorrhoea	15.64	10.36	5	119670	57	90508715
Bronchitis	15.60	10.36	128	119547	152799	90355973
Band neutrophil count decreased	15.59	10.36	6	119669	122	90508650
Folate deficiency	15.49	10.36	20	119655	3145	90505627
Dysmorphism	15.44	10.36	18	119657	2550	90506222
Wound haemorrhage	15.44	10.36	19	119656	2848	90505924
Product dose omission in error	15.43	10.36	4	119671	20499	90488273
Splenic haematoma	15.41	10.36	6	119669	126	90508646
Injection site necrosis	15.35	10.36	14	119661	1487	90507285
Klebsiella bacteraemia	15.30	10.36	18	119657	2574	90506198
Anti factor X activity increased	15.22	10.36	4	119671	21	90508751
Cardiomyopathy alcoholic	15.22	10.36	4	119671	21	90508751
Thrombectomy	15.21	10.36	7	119668	225	90508547
Renal artery thrombosis	15.19	10.36	6	119669	131	90508641
Angiokeratoma	15.19	10.36	6	119669	131	90508641
Tubulointerstitial nephritis	15.13	10.36	70	119605	25273	90483499
Bone lesion	15.09	10.36	29	119646	6408	90502364
Subchorionic haematoma	15.06	10.36	6	119669	134	90508638
Normal newborn	15.05	10.36	66	119609	23296	90485476
Myelomalacia	15.05	10.36	5	119670	65	90508707
Tissue infiltration	15	10.36	11	119664	859	90507913
Tinnitus	14.98	10.36	21	119654	43081	90465691
Myocardial rupture	14.98	10.36	5	119670	66	90508706
Febrile bone marrow aplasia	14.97	10.36	37	119638	9701	90499071
Subcapsular splenic haematoma	14.92	10.36	4	119671	23	90508749
Iliac vein occlusion	14.92	10.36	4	119671	23	90508749
Protein C deficiency	14.92	10.36	4	119671	23	90508749
Chronic spontaneous urticaria	14.87	10.36	15	119660	1805	90506967
Device related thrombosis	14.86	10.36	16	119659	2077	90506695
Osteopenia	14.83	10.36	65	119610	22937	90485835
Subcapsular renal haematoma	14.79	10.36	8	119667	365	90508407
Allergic sinusitis	14.73	10.36	16	119659	2097	90506675
Haematoma infection	14.70	10.36	10	119665	693	90508079
Subcutaneous emphysema	14.68	10.36	12	119663	1100	90507672
Skin test positive	14.67	10.36	11	119664	889	90507883
Colitis	14.63	10.36	149	119526	69793	90438979
Monoplegia	14.62	10.36	21	119654	3653	90505119
Placenta praevia	14.56	10.36	12	119663	1113	90507659
Splenic rupture	14.44	10.36	13	119662	1358	90507414
Oropharyngeal pain	14.37	10.36	91	119584	115096	90393676
Pulmonary oedema	14.33	10.36	135	119540	61945	90446827
Eosinophilic pneumonia	14.33	10.36	18	119657	2755	90506017
Dermatitis exfoliative	14.30	10.36	26	119649	5510	90503262
International normalised ratio fluctuation	14.29	10.36	19	119656	3074	90505698
Bicytopenia	14.20	10.36	21	119654	3750	90505022
Consciousness fluctuating	14.18	10.36	11	119664	935	90507837
Nephrolithiasis	14.18	10.36	27	119648	49058	90459714
Injection site nodule	14.18	10.36	23	119652	4450	90504322
Palpitations	14.15	10.36	114	119561	136614	90372158
Impaired work ability	14.11	10.36	4	119671	19322	90489450
Ileus	14.08	10.36	51	119624	16495	90492277
Carpal tunnel syndrome	14.05	10.36	7	119668	23921	90484851
Chemical burns of eye	14.04	10.36	5	119670	81	90508691
Quadriplegia	14.02	10.36	16	119659	2215	90506557
Wrong technique in product usage process	14.00	10.36	48	119627	71523	90437249
Occupational exposure to product	14.00	10.36	17	119658	2514	90506258
Hypertonia neonatal	13.98	10.36	7	119668	272	90508500
Nail toxicity	13.94	10.36	8	119667	410	90508362
Liver abscess	13.94	10.36	20	119655	3476	90505296
Abdominal tenderness	13.88	10.36	35	119640	9289	90499483
Hypovolaemia	13.88	10.36	42	119633	12389	90496383
Neutrophil count decreased	13.84	10.36	150	119525	71382	90437390
Ventricular tachycardia	13.84	10.36	67	119608	24641	90484131
Infusion site reaction	13.79	10.36	4	119671	19035	90489737
Deafness bilateral	13.78	10.36	14	119661	1699	90507073
Prothrombin time shortened	13.75	10.36	16	119659	2262	90506510
Abdominal sepsis	13.75	10.36	13	119662	1446	90507326
Pulmonary infarction	13.73	10.36	18	119657	2874	90505898
Gastroduodenal haemorrhage	13.66	10.36	5	119670	88	90508684
Vascular pseudoaneurysm ruptured	13.66	10.36	5	119670	88	90508684
Pituitary haemorrhage	13.66	10.36	5	119670	88	90508684
Foetal heart rate disorder	13.64	10.36	6	119669	173	90508599
Unmasking of previously unidentified disease	13.62	10.36	13	119662	1463	90507309
Sputum discoloured	13.51	10.36	5	119670	20386	90488386
Factor XIII Inhibition	13.46	10.36	4	119671	35	90508737
Pneumonia mycoplasmal	13.43	10.36	11	119664	1011	90507761
Transfusion-related acute lung injury	13.42	10.36	6	119669	180	90508592
Pulmonary congestion	13.37	10.36	56	119619	19377	90489395
Infective glossitis	13.36	10.36	4	119671	36	90508736
Maternal exposure during breast feeding	13.35	10.36	27	119648	6193	90502579
Anterior chamber cleavage syndrome	13.33	10.36	6	119669	183	90508589
Eye disorder	13.32	10.36	10	119665	27380	90481392
Subileus	13.31	10.36	20	119655	3624	90505148
Hypoglycaemia	13.30	10.36	146	119529	69702	90439070
Lipid metabolism disorder	13.30	10.36	6	119669	184	90508588
Tricuspid valve stenosis	13.29	10.36	3	119672	7	90508765
Herpes zoster	13.28	10.36	72	119603	94572	90414200
Injection site haemorrhage	13.23	10.36	73	119602	28245	90480527
Arm amputation	13.17	10.36	4	119671	38	90508734
Pancreatic carcinoma metastatic	13.14	10.36	16	119659	2372	90506400
Inguinal hernia	13.11	10.36	15	119660	2083	90506689
Myalgia	13.09	10.36	158	119517	174967	90333805
Pelvic fluid collection	13.09	10.36	11	119664	1048	90507724
Uterine hypertonus	13.05	10.36	7	119668	314	90508458
Aspiration	13.05	10.36	48	119627	15645	90493127
Vitiligo	13.04	10.36	15	119660	2095	90506677
Death	13.00	10.36	732	118943	455819	90052953
Ureteric obstruction	12.99	10.36	15	119660	2103	90506669
Procalcitonin increased	12.98	10.36	13	119662	1551	90507221
COVID-19	12.93	10.36	303	119372	168540	90340232
Basal cell carcinoma	12.92	10.36	15	119660	33374	90475398
Gastric disorder	12.92	10.36	15	119660	33369	90475403
Coordination abnormal	12.92	10.36	6	119669	21350	90487422
Lung disorder	12.88	10.36	131	119544	149752	90359020
Cerebral ischaemia	12.86	10.36	29	119646	7167	90501605
Tracheobronchitis	12.84	10.36	13	119662	1572	90507200
Posterior reversible encephalopathy syndrome	12.82	10.36	61	119614	22278	90486494
Pseudomonas infection	12.81	10.36	46	119629	14819	90493953
Subdural haemorrhage	12.80	10.36	19	119656	3404	90505368
Humerus fracture	12.80	10.36	35	119640	9750	90499022
Parenteral nutrition associated liver disease	12.75	10.36	3	119672	9	90508763
Gastroenteritis clostridial	12.70	10.36	9	119666	666	90508106
Ischaemic hepatitis	12.67	10.36	17	119658	2776	90505996
Respiratory acidosis	12.64	10.36	31	119644	8088	90500684
Atrial flutter	12.63	10.36	37	119638	10721	90498051
Microcytic anaemia	12.60	10.36	20	119655	3798	90504974
Portal vein thrombosis	12.58	10.36	18	119657	3120	90505652
Hyperacusis	12.58	10.36	17	119658	2794	90505978
Drug tolerance	12.55	10.36	4	119671	17912	90490860
Fat embolism	12.54	10.36	7	119668	340	90508432
Angioedema	12.53	10.36	136	119539	64740	90444032
Pemphigoid	12.53	10.36	33	119642	8993	90499779
Coloboma	12.50	10.36	5	119670	113	90508659
Hallucination, visual	12.50	10.36	62	119613	23030	90485742
Swelling face	12.49	10.36	60	119615	81292	90427480
Chronic sinusitis	12.49	10.36	8	119667	23794	90484978
Preterm premature rupture of membranes	12.46	10.36	13	119662	1628	90507144
Photosensitivity reaction	12.43	10.36	4	119671	17803	90490969
Injection site thrombosis	12.42	10.36	5	119670	115	90508657
Tongue fungal infection	12.42	10.36	5	119670	115	90508657
Orbital oedema	12.41	10.36	7	119668	347	90508425
Hypochromasia	12.41	10.36	7	119668	347	90508425
Blood disorder	12.40	10.36	30	119645	7760	90501012
Left ventricular hypertrophy	12.39	10.36	26	119649	6118	90502654
Diabetes mellitus	12.36	10.36	44	119631	64831	90443941
Panic attack	12.34	10.36	10	119665	26355	90482417
Abdominal pain lower	12.28	10.36	75	119600	30102	90478670
Acute pulmonary oedema	12.27	10.36	34	119641	9546	90499226
Hepatic vein thrombosis	12.25	10.36	6	119669	222	90508550
Gingival erosion	12.23	10.36	6	119669	223	90508549
Agitation	12.21	10.36	139	119536	66959	90441813
Prothrombin time abnormal	12.16	10.36	8	119667	524	90508248
Small intestinal haemorrhage	12.15	10.36	15	119660	2256	90506516
Haemorrhagic ovarian cyst	12.10	10.36	9	119666	718	90508054
PIK3CA related overgrowth spectrum	12.08	10.36	3	119672	12	90508760
Hemivertebra	12.07	10.36	5	119670	124	90508648
Foetal distress syndrome	12.05	10.36	13	119662	1692	90507080
Superior vena cava syndrome	12.04	10.36	9	119666	724	90508048
Altered state of consciousness	11.98	10.36	77	119598	31455	90477317
Hydrocholecystis	11.97	10.36	4	119671	53	90508719
Catheter site inflammation	11.95	10.36	10	119665	947	90507825
Generalised tonic-clonic seizure	11.92	10.36	83	119592	34820	90473952
Paraneoplastic rash	11.92	10.36	5	119670	128	90508644
Status epilepticus	11.92	10.36	53	119622	18821	90489951
Hyperventilation	11.90	10.36	27	119648	6701	90502071
Neurotoxicity	11.87	10.36	58	119617	21409	90487363
Paronychia	11.86	10.36	30	119645	7976	90500796
Musculoskeletal disorder	11.86	10.36	7	119668	21762	90487010
Extravasation blood	11.85	10.36	5	119670	130	90508642
Hyperpyrexia	11.85	10.36	22	119653	4739	90504033
Hypercreatininaemia	11.82	10.36	9	119666	744	90508028
Tumour lysis syndrome	11.82	10.36	37	119638	11115	90497657
Catheter site haemorrhage	11.81	10.36	19	119656	3649	90505123
Lactic acidosis	11.78	10.36	110	119565	50353	90458419
Long QT syndrome	11.78	10.36	20	119655	4017	90504755
Prosthetic cardiac valve thrombosis	11.77	10.36	4	119671	56	90508716
Off label use	11.74	10.36	1643	118032	1100609	89408163
Staphylococcal sepsis	11.72	10.36	33	119642	9350	90499422
Anti-platelet antibody positive	11.70	10.36	4	119671	57	90508715
Seasonal allergy	11.69	10.36	8	119667	22975	90485797
Rhabdomyolysis	11.60	10.36	111	119564	51145	90457627
Malignant neoplasm progression	11.58	10.36	202	119473	106668	90402104
Klebsiella sepsis	11.58	10.36	13	119662	1768	90507004
Drug dependence	11.54	10.36	13	119662	29314	90479458
Thromboembolectomy	11.51	10.36	4	119671	60	90508712
Abdominal compartment syndrome	11.51	10.36	9	119666	774	90507998
Immobilisation prolonged	11.50	10.36	5	119670	140	90508632
Laryngeal oedema	11.49	10.36	27	119648	6854	90501918
Underdose	11.42	10.36	35	119640	53982	90454790
Neutropenic infection	11.41	10.36	13	119662	1796	90506976
Post thrombotic syndrome	11.41	10.36	8	119667	582	90508190
Hydrocephalus	11.39	10.36	25	119650	6069	90502703
Gastrointestinal dilation procedure	11.38	10.36	3	119672	16	90508756
Thrombolysis	11.34	10.36	5	119670	145	90508627
Vascular stent occlusion	11.33	10.36	4	119671	63	90508709
Eye pain	11.32	10.36	26	119649	44142	90464630
Oral pain	11.29	10.36	16	119659	32667	90476105
Diabetic retinal oedema	11.27	10.36	7	119668	415	90508357
Myocardial ischaemia	11.27	10.36	42	119633	13772	90495000
Dermo-hypodermitis	11.27	10.36	9	119666	798	90507974
Venous thrombosis limb	11.24	10.36	18	119657	3444	90505328
Sepsis neonatal	11.14	10.36	8	119667	605	90508167
Osmotic demyelination syndrome	11.11	10.36	10	119665	1044	90507728
Coagulation factor X level decreased	11.11	10.36	4	119671	67	90508705
Gastrointestinal injury	11.10	10.36	9	119666	815	90507957
Transverse sinus thrombosis	11.09	10.36	8	119667	609	90508163
Nasal herpes	11.08	10.36	9	119666	817	90507955
Incision site haemorrhage	11.08	10.36	8	119667	610	90508162
Hyperlipasaemia	11.04	10.36	9	119666	822	90507950
Gingival discomfort	11.03	10.36	7	119668	431	90508341
Wound infection staphylococcal	10.91	10.36	16	119659	2837	90505935
Endocarditis	10.90	10.36	27	119648	7086	90501686
Procedural pain	10.87	10.36	17	119658	33343	90475429
Urinary tract infection bacterial	10.87	10.36	25	119650	6260	90502512
Dermatitis atopic	10.87	10.36	9	119666	23463	90485309
Gastrointestinal mucosal disorder	10.85	10.36	9	119666	842	90507930
Haematidrosis	10.84	10.36	4	119671	72	90508700
Diffuse large B-cell lymphoma stage II	10.84	10.36	4	119671	72	90508700
Contraindicated product prescribed	10.82	10.36	12	119663	1610	90507162
Scar pain	10.80	10.36	6	119669	289	90508483
Metastases to lymph nodes	10.79	10.36	37	119638	11652	90497120
Dry gangrene	10.77	10.36	8	119667	637	90508135
Pulmonary sepsis	10.77	10.36	14	119661	2217	90506555
Cognitive disorder	10.76	10.36	51	119624	69356	90439416
Mitral valve stenosis	10.74	10.36	11	119664	1348	90507424
Peripheral embolism	10.73	10.36	11	119664	1349	90507423
Bacteroides test positive	10.68	10.36	3	119672	21	90508751
Median nerve injury	10.68	10.36	3	119672	21	90508751
Flank pain	10.68	10.36	52	119623	19170	90489602
Hypofibrinogenaemia	10.67	10.36	11	119664	1359	90507413
Uterine haemorrhage	10.64	10.36	21	119654	4731	90504041
Feeling hot	10.59	10.36	60	119615	77948	90430824
Flagellate dermatitis	10.55	10.36	5	119670	172	90508600
Femur fracture	10.53	10.36	100	119575	45982	90462790
Injection site plaque	10.52	10.36	5	119670	173	90508599
Troponin increased	10.52	10.36	40	119635	13241	90495531
Hyperchloraemia	10.52	10.36	9	119666	879	90507893
Escherichia urinary tract infection	10.45	10.36	41	119634	13774	90494998
Immune thrombocytopenia	10.45	10.36	40	119635	13286	90495486
Retroplacental haematoma	10.44	10.36	5	119670	176	90508596
Renal vascular thrombosis	10.41	10.36	4	119671	81	90508691
Breast injury	10.41	10.36	4	119671	81	90508691
Hepatic infection	10.40	10.36	8	119667	672	90508100
Intestinal haemorrhage	10.38	10.36	20	119655	4427	90504345
Hyperaemia	10.37	10.36	15	119660	2627	90506145
Female sterilisation	10.36	10.36	8	119667	675	90508097

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Heparin-induced thrombocytopenia	773.48	10.79	360	104206	6237	42510532
Haematoma	528.20	10.79	483	104083	27540	42489229
Thrombocytopenia	455.93	10.79	1255	103311	189024	42327745
Hepatic cytolysis	336.65	10.79	371	104195	26473	42490296
Haematoma muscle	324.38	10.79	140	104426	2010	42514759
Hepatocellular injury	306.92	10.79	333	104233	23345	42493424
Shock haemorrhagic	296.33	10.79	275	104291	15967	42500802
Haemorrhage	295.85	10.79	532	104034	60031	42456738
Retroperitoneal haemorrhage	293.60	10.79	147	104419	3008	42513761
Retroperitoneal haematoma	283.46	10.79	142	104424	2909	42513860
Drug ineffective	269.99	10.79	732	103834	629465	41887304
Abdominal wall haematoma	269.91	10.79	126	104440	2196	42514573
Drug reaction with eosinophilia and systemic symptoms	263.32	10.79	413	104153	41662	42475107
Pulmonary embolism	257.72	10.79	760	103806	118852	42397917
Rash maculo-papular	248.52	10.79	378	104188	37125	42479644
Eosinophilia	240.13	10.79	347	104219	32552	42484217
Cholestasis	233.02	10.79	342	104224	32537	42484232
Toxicity to various agents	229.79	10.79	139	104427	228997	42287772
Deep vein thrombosis	227.49	10.79	550	104016	76407	42440362
Muscle haemorrhage	209.53	10.79	129	104437	3996	42512773
Drug abuse	194.15	10.79	17	104549	104754	42412015
Anaemia	183.21	10.79	1245	103321	279033	42237736
Mixed liver injury	140.88	10.79	104	104462	4370	42512399
Acute kidney injury	139.86	10.79	1445	103121	365892	42150877
Haematuria	137.64	10.79	381	104185	57418	42459351
Intra-abdominal haematoma	133.52	10.79	69	104497	1512	42515257
Product dose omission issue	133.07	10.79	110	104456	154255	42362514
Agranulocytosis	130.75	10.79	254	104312	30358	42486411
Haemoglobin decreased	107.83	10.79	623	103943	131848	42384921
Cerebral haemorrhage	105.04	10.79	269	104297	38697	42478072
Cytokine release syndrome	104.49	10.79	292	104274	44235	42472534
Post procedural haemorrhage	95.37	10.79	116	104450	9196	42507573
Asthma	92.29	10.79	20	104546	62294	42454475
Death	90.85	10.79	731	103835	470454	42046315
Bullous haemorrhagic dermatosis	90.12	10.79	25	104541	78	42516691
Headache	88.88	10.79	296	104270	239073	42277696
International normalised ratio decreased	88.41	10.79	80	104486	4492	42512277
Melaena	84.03	10.79	247	104319	38499	42478270
Premature baby	83.33	10.79	179	104387	22974	42493795
Acute generalised exanthematous pustulosis	83.08	10.79	104	104462	8491	42508278
Therapeutic product effect incomplete	83.00	10.79	35	104531	70904	42445865
Haemorrhage intracranial	81.28	10.79	149	104417	17043	42499726
Intentional product misuse	80.05	10.79	26	104540	61874	42454895
Haematemesis	78.83	10.79	206	104360	29993	42486776
Insomnia	75.56	10.79	108	104458	118145	42398624
Fatigue	74.92	10.79	696	103870	434945	42081824
Embolism	72.19	10.79	98	104468	8665	42508104
Toxic skin eruption	70.03	10.79	123	104443	13607	42503162
Weight increased	69.60	10.79	98	104468	107885	42408884
Gastrointestinal haemorrhage	68.93	10.79	443	104123	97283	42419486
Nasopharyngitis	68.51	10.79	63	104503	83933	42432836
International normalised ratio increased	66.48	10.79	264	104302	47904	42468865
Leukopenia	65.69	10.79	359	104207	74387	42442382
Post procedural haematoma	65.65	10.79	44	104522	1581	42515188
Erysipelas	65.40	10.79	79	104487	6217	42510552
Hypertransaminasaemia	65.36	10.79	96	104470	9131	42507638
Haemoperitoneum	64.99	10.79	48	104518	2018	42514751
Gastric haemorrhage	64.05	10.79	102	104464	10413	42506356
Thrombocytosis	63.32	10.79	68	104498	4707	42512062
Cerebral haematoma	62.58	10.79	73	104493	5537	42511232
Inappropriate schedule of product administration	61.83	10.79	87	104479	95815	42420954
Neutropenia	61.69	10.79	754	103812	198677	42318092
General physical health deterioration	61.59	10.79	604	103962	150642	42366127
Heparin-induced thrombocytopenia test	61.24	10.79	21	104545	153	42516616
Hepatitis	61.07	10.79	176	104390	27124	42489645
Vascular purpura	60.39	10.79	47	104519	2139	42514630
Arthralgia	60.04	10.79	279	104287	204959	42311810
Dizziness	58.97	10.79	364	104202	248890	42267879
Hypovolaemic shock	58.34	10.79	88	104478	8571	42508198
Upper gastrointestinal haemorrhage	58.07	10.79	185	104381	30114	42486655
Foetal exposure during pregnancy	57.97	10.79	250	104316	47061	42469708
Intentional overdose	57.64	10.79	27	104539	51429	42465340
Alanine aminotransferase increased	57.64	10.79	393	104173	88013	42428756
Clostridium test positive	57.06	10.79	69	104497	5436	42511333
Rheumatoid arthritis	56.35	10.79	17	104549	42423	42474346
Joint swelling	55.49	10.79	51	104515	67971	42448798
Respiratory failure	54.77	10.79	517	104049	127615	42389154
Toxic epidermal necrolysis	53.72	10.79	166	104400	26584	42490185
Myalgia	53.58	10.79	96	104470	95984	42420785
Suicidal ideation	52.84	10.79	26	104540	48135	42468634
Chest wall haematoma	51.26	10.79	20	104546	218	42516551
Musculoskeletal stiffness	51.17	10.79	40	104526	57725	42459044
Hypotension	50.47	10.79	900	103666	256731	42260038
Hypoxia	50.21	10.79	318	104248	69468	42447301
Loss of personal independence in daily activities	50.12	10.79	30	104536	49786	42466983
Treatment failure	49.85	10.79	48	104518	62576	42454193
Drug intolerance	49.84	10.79	75	104491	80349	42436420
Ischaemic stroke	49.41	10.79	143	104423	22090	42494679
Liver function test increased	47.74	10.79	132	104434	19866	42496903
Abdominal discomfort	46.80	10.79	70	104496	75185	42441584
Blood loss anaemia	46.80	10.79	85	104481	9651	42507118
Blood pressure increased	45.82	10.79	115	104451	101813	42414956
Compartment syndrome	45.67	10.79	48	104518	3241	42513528
COVID-19 treatment	45.50	10.79	19	104547	250	42516519
Petechiae	45.04	10.79	87	104479	10348	42506421
Malaise	44.54	10.79	321	104245	211835	42304934
Hospitalisation	44.44	10.79	71	104495	74259	42442510
Subdural haematoma	44.09	10.79	141	104425	22997	42493772
Heparin-induced thrombocytopenia test positive	44.02	10.79	15	104551	107	42516662
Blood pressure fluctuation	43.32	10.79	7	104559	26901	42489868
COVID-19 pneumonia	43.29	10.79	134	104432	21479	42495290
Venous thrombosis	42.52	10.79	51	104515	3984	42512785
Acetabulum fracture	41.88	10.79	21	104545	431	42516338
Spinal cord haemorrhage	41.82	10.79	19	104547	310	42516459
Depression	41.74	10.79	137	104429	111226	42405543
Therapeutic product effect decreased	41.65	10.79	22	104544	39128	42477641
Suture rupture	40.76	10.79	21	104545	457	42516312
Injury associated with device	40.70	10.79	31	104535	1366	42515403
Purpura	40.64	10.79	90	104476	11789	42504980
Weight decreased	40.62	10.79	321	104245	207627	42309142
Palpitations	40.35	10.79	39	104527	50758	42466011
Drug dependence	39.83	10.79	11	104555	29083	42487686
Feeling abnormal	39.56	10.79	69	104497	69717	42447052
Low birth weight baby	39.36	10.79	80	104486	9875	42506894
International normalised ratio abnormal	38.95	10.79	45	104521	3378	42513391
Hypokalaemia	38.81	10.79	305	104261	71416	42445353
Thrombosis	37.98	10.79	293	104273	68218	42448551
Haematocrit decreased	37.91	10.79	178	104388	34730	42482039
Hepatitis acute	37.73	10.79	74	104492	8901	42507868
Febrile neutropenia	36.76	10.79	650	103916	185053	42331716
Ecchymosis	36.40	10.79	67	104499	7685	42509084
Myelosuppression	35.85	10.79	28	104538	40433	42476336
Pain	35.44	10.79	407	104159	244441	42272328
Electrocardiogram QT prolonged	35.42	10.79	220	104346	47725	42469044
Hypofibrinogenaemia	35.27	10.79	33	104533	1934	42514835
Transaminases increased	35.21	10.79	167	104399	32718	42484051
Pruritus	35.21	10.79	295	104271	188476	42328293
Hypocoagulable state	35.20	10.79	25	104541	988	42515781
Pancytopenia	34.98	10.79	442	104124	117301	42399468
Anticoagulation drug level below therapeutic	34.91	10.79	25	104541	1001	42515768
Septic shock	34.82	10.79	361	104205	91311	42425458
Drug hypersensitivity	34.72	10.79	126	104440	99263	42417506
Splenic infarction	34.69	10.79	36	104530	2395	42514374
Soft tissue disorder	34.20	10.79	23	104543	831	42515938
Haemodynamic instability	34.14	10.79	87	104479	12470	42504299
Dry skin	34.07	10.79	41	104525	48297	42468472
Heart rate decreased	34.03	10.79	24	104542	36508	42480261
Influenza	33.87	10.79	63	104503	62112	42454657
Acute respiratory failure	33.69	10.79	186	104380	38672	42478097
Coagulation time prolonged	33.64	10.79	28	104538	1404	42515365
Rash morbilliform	33.53	10.79	46	104520	4107	42512662
Diabetes mellitus	33.52	10.79	60	104506	60027	42456742
Arterial haemorrhage	33.03	10.79	26	104540	1203	42515566
Alveolar lung disease	32.91	10.79	18	104548	444	42516325
Respiratory distress	32.86	10.79	195	104371	41625	42475144
Coagulopathy	32.63	10.79	124	104442	22038	42494731
Intra-abdominal haemorrhage	32.49	10.79	38	104528	2890	42513879
Psoriasis	32.41	10.79	43	104523	48561	42468208
Blood blister	32.37	10.79	33	104533	2150	42514619
Pulmonary interstitial emphysema syndrome	32.19	10.79	19	104547	544	42516225
Pelvic haematoma	31.52	10.79	14	104552	216	42516553
Vascular device infection	31.50	10.79	55	104511	6055	42510714
Cholestatic liver injury	31.34	10.79	42	104524	3667	42513102
Hypercapnic coma	31.00	10.79	13	104553	173	42516596
Epistaxis	30.73	10.79	274	104292	66552	42450217
Anti factor V antibody	30.26	10.79	15	104551	300	42516469
Long QT syndrome	30.09	10.79	38	104528	3129	42513640
Autoimmune heparin-induced thrombocytopenia	29.96	10.79	9	104557	40	42516729
Abdominal mass	29.93	10.79	33	104533	2353	42514416
Activated partial thromboplastin time abnormal	29.65	10.79	12	104554	145	42516624
Haemothorax	29.45	10.79	49	104517	5187	42511582
Obstructive airways disorder	29.29	10.79	12	104554	24747	42492022
Symmetrical drug-related intertriginous and flexural exanthema	29.19	10.79	21	104545	847	42515922
Paraplegia	28.88	10.79	38	104528	3259	42513510
Prothrombin time abnormal	28.87	10.79	21	104545	862	42515907
Dermatitis bullous	28.85	10.79	64	104502	8392	42508377
Extradural haematoma	28.83	10.79	25	104541	1326	42515443
Atrial fibrillation	28.83	10.79	492	104074	139101	42377668
Hepatitis cholestatic	28.75	10.79	70	104496	9754	42507015
Injection site haematoma	28.36	10.79	29	104537	1896	42514873
Product use issue	28.35	10.79	95	104471	76656	42440113
Therapy non-responder	28.24	10.79	55	104511	53304	42463465
Scrotal haematoma	28.14	10.79	10	104556	82	42516687
Vascular stent thrombosis	27.84	10.79	37	104529	3205	42513564
Therapeutic response decreased	27.60	10.79	30	104536	36982	42479787
Haemarthrosis	27.46	10.79	41	104525	3957	42512812
Product use in unapproved indication	27.30	10.79	305	104261	184151	42332618
Urinary tract infection pseudomonal	27.30	10.79	24	104542	1297	42515472
Memory impairment	27.25	10.79	51	104515	50171	42466598
Pulmonary fibrosis	26.93	10.79	16	104550	26665	42490104
Vascular pseudoaneurysm	26.50	10.79	33	104533	2679	42514090
Haemorrhagic transformation stroke	26.42	10.79	27	104539	1764	42515005
Prothrombin time prolonged	26.16	10.79	66	104500	9403	42507366
Wheezing	26.04	10.79	60	104506	54721	42462048
Bronchial haemorrhage	25.92	10.79	18	104548	686	42516083
Haemoptysis	25.89	10.79	198	104368	45969	42470800
Fibrin D dimer increased	25.86	10.79	45	104521	4940	42511829
Cell death	25.76	10.79	34	104532	2925	42513844
Spinal cord compression	25.76	10.79	41	104525	4183	42512586
Tachycardia	25.70	10.79	369	104197	100718	42416051
Peripheral swelling	25.59	10.79	124	104442	90146	42426623
Nausea	25.31	10.79	761	103805	396038	42120731
Synovitis	25.17	10.79	4	104562	15563	42501206
Adverse drug reaction	25.08	10.79	33	104533	37401	42479368
Catheter site haemorrhage	24.89	10.79	31	104535	2517	42514252
Patient restraint	24.89	10.79	9	104557	78	42516691
Sinusitis	24.81	10.79	49	104517	47243	42469526
Gastrointestinal disorder	24.77	10.79	48	104518	46605	42470164
Ureteric compression	24.63	10.79	13	104553	298	42516471
Gait disturbance	24.23	10.79	141	104425	97859	42418910
Urinary retention	24.21	10.79	182	104384	42032	42474737
Catheter site haematoma	23.97	10.79	11	104555	184	42516585
Accidental exposure to product	23.94	10.79	10	104556	20383	42496386
Splenic cyst	23.92	10.79	10	104556	132	42516637
Erectile dysfunction	23.69	10.79	16	104550	24897	42491872
Full blood count abnormal	23.65	10.79	23	104543	29853	42486916
Intestinal infarction	23.55	10.79	16	104550	588	42516181
Pelvic haemorrhage	23.51	10.79	6	104560	12	42516757
Peripheral artery thrombosis	23.50	10.79	31	104535	2666	42514103
Pneumonitis	23.44	10.79	179	104387	41539	42475230
Muscle spasms	23.36	10.79	120	104446	85924	42430845
Duodenal ulcer haemorrhage	23.35	10.79	47	104519	5761	42511008
Vision blurred	23.04	10.79	62	104504	53637	42463132
Dry eye	22.90	10.79	5	104561	15501	42501268
Thrombosis in device	22.67	10.79	33	104533	3113	42513656
Aspartate aminotransferase increased	22.62	10.79	289	104277	76874	42439895
Incision site haematoma	22.60	10.79	9	104557	104	42516665
Arthritis	22.57	10.79	43	104523	42022	42474747
Wrong technique in product usage process	22.52	10.79	44	104522	42591	42474178
Thrombophlebitis	22.43	10.79	37	104529	3889	42512880
Blood glucose increased	22.21	10.79	99	104467	73600	42443169
Cyanosis	22.04	10.79	84	104482	14947	42501822
Intentional product use issue	21.95	10.79	96	104470	71737	42445032
Diet refusal	21.83	10.79	12	104554	299	42516470
Off label use	21.74	10.79	1832	102734	636503	41880266
Intracranial haematoma	21.73	10.79	15	104551	566	42516203
Splenic necrosis	21.72	10.79	9	104557	116	42516653
Cough	21.67	10.79	307	104259	177796	42338973
Sepsis	21.60	10.79	641	103925	198693	42318076
Pneumonia acinetobacter	21.58	10.79	11	104555	234	42516535
Jugular vein thrombosis	21.50	10.79	26	104540	2048	42514721
Neuropathy peripheral	21.39	10.79	154	104412	101699	42415070
Phlebitis infective	21.38	10.79	9	104557	121	42516648
Nightmare	21.30	10.79	18	104548	24994	42491775
Adrenal haemorrhage	21.10	10.79	12	104554	320	42516449
Sleep disorder	21.03	10.79	55	104511	48040	42468729
Urethral valves	20.92	10.79	11	104555	250	42516519
Peripheral ischaemia	20.92	10.79	48	104518	6437	42510332
Haemorrhagic stroke	20.87	10.79	52	104514	7350	42509419
Subcutaneous haematoma	20.86	10.79	19	104547	1076	42515693
Wound haemorrhage	20.81	10.79	27	104539	2284	42514485
Cardiac tamponade	20.65	10.79	48	104518	6492	42510277
Bladder cancer	20.60	10.79	8	104558	17039	42499730
Neck pain	20.58	10.79	26	104540	29988	42486781
Congenital multiplex arthrogryposis	20.46	10.79	11	104555	262	42516507
Diplegia	20.41	10.79	20	104546	1242	42515527
Hepatic haematoma	20.38	10.79	13	104553	429	42516340
Pyelocaliectasis	20.35	10.79	21	104545	1388	42515381
Gamma-glutamyltransferase increased	20.29	10.79	143	104423	32354	42484415
Venous thrombosis limb	20.28	10.79	27	104539	2342	42514427
Ocular hyperaemia	20.12	10.79	7	104559	15956	42500813
Splenic haemorrhage	19.99	10.79	14	104552	541	42516228
Osteoma	19.97	10.79	8	104558	94	42516675
Traumatic haematoma	19.78	10.79	16	104550	770	42515999
Balance disorder	19.70	10.79	56	104510	47589	42469180
Tachypnoea	19.66	10.79	105	104461	21557	42495212
Anger	19.63	10.79	4	104562	13014	42503755
Polycystic liver disease	19.60	10.79	8	104558	99	42516670
Immobilisation prolonged	19.60	10.79	5	104561	10	42516759
Hypospadias	19.56	10.79	33	104533	3534	42513235
Glycosylated haemoglobin increased	19.43	10.79	4	104562	12920	42503849
Anticoagulant-related nephropathy	19.42	10.79	9	104557	154	42516615
Splenic rupture	19.32	10.79	22	104544	1625	42515144
Drug withdrawal syndrome	18.98	10.79	15	104551	21534	42495235
Eye pain	18.97	10.79	9	104557	17021	42499748
Psoriatic arthropathy	18.88	10.79	20	104546	24947	42491822
Lymphocele	18.72	10.79	21	104545	1526	42515243
Dry mouth	18.69	10.79	44	104522	39835	42476934
Hypertension	18.68	10.79	293	104273	166911	42349858
Gynaecomastia	18.67	10.79	4	104562	12563	42504206
Lymphoedema	18.66	10.79	39	104527	4909	42511860
Spinal cord haematoma	18.65	10.79	8	104558	113	42516656
Irritability	18.63	10.79	25	104541	28103	42488666
Appendicitis	18.60	10.79	14	104552	20599	42496170
Intentional self-injury	18.59	10.79	7	104559	15195	42501574
Hypersensitivity	18.49	10.79	103	104463	72267	42444502
Suicide attempt	18.47	10.79	55	104511	46045	42470724
Subclavian vein thrombosis	18.42	10.79	17	104549	979	42515790
Embolism venous	18.32	10.79	23	104543	1883	42514886
Procedural site reaction	18.25	10.79	9	104557	178	42516591
Rectal haemorrhage	18.19	10.79	194	104372	49412	42467357
Coronary artery perforation	18.13	10.79	7	104559	74	42516695
Foetal growth restriction	18.04	10.79	40	104526	5243	42511526
Incision site haemorrhage	17.93	10.79	13	104553	531	42516238
Procedural haemorrhage	17.91	10.79	28	104538	2813	42513956
Tinnitus	17.90	10.79	27	104539	28911	42487858
Plasma cell myeloma	17.88	10.79	187	104379	47391	42469378
Device safety feature issue	17.70	10.79	6	104560	42	42516727
Chest discomfort	17.67	10.79	88	104478	63528	42453241
Rash	17.66	10.79	531	104035	276423	42240346
Dyspepsia	17.54	10.79	48	104518	41304	42475465
Stress	17.53	10.79	53	104513	44159	42472610
Migraine	17.44	10.79	22	104544	25392	42491377
Skin necrosis	17.43	10.79	44	104522	6270	42510499
Pulmonary infarction	17.39	10.79	20	104546	1494	42515275
Bronchopleural fistula	17.32	10.79	14	104552	673	42516096
Labelled drug-drug interaction medication error	17.31	10.79	80	104486	15502	42501267
Interstitial lung disease	17.27	10.79	117	104449	78345	42438424
Flushing	17.24	10.79	41	104525	36987	42479782
Injection site thrombosis	17.23	10.79	6	104560	46	42516723
Klebsiella infection	17.17	10.79	64	104502	11268	42505501
Pituitary haemorrhage	17.14	10.79	9	104557	204	42516565
Renal disorder	17.02	10.79	28	104538	28952	42487817
Haemoglobin urine present	17.00	10.79	8	104558	142	42516627
Renal infarct	16.96	10.79	22	104544	1861	42514908
Pyrexia	16.88	10.79	1152	103414	392890	42123879
Hemiplegia	16.85	10.79	50	104516	7829	42508940
Cerebral artery occlusion	16.84	10.79	15	104551	825	42515944
Underdose	16.81	10.79	10	104556	16656	42500113
Swelling face	16.77	10.79	26	104540	27528	42489241
Injection site haemorrhage	16.73	10.79	65	104501	11671	42505098
Dermatitis exfoliative	16.72	10.79	46	104520	6901	42509868
Diabetic bullosis	16.69	10.79	5	104561	22	42516747
Haemorrhage coronary artery	16.69	10.79	5	104561	22	42516747
Prostate cancer	16.66	10.79	55	104511	44588	42472181
Disorientation	16.61	10.79	149	104417	36240	42480529
Dysgeusia	16.61	10.79	37	104529	34152	42482617
Cerebral palsy	16.59	10.79	11	104555	388	42516381
Device toxicity	16.51	10.79	5	104561	23	42516746
Adrenal thrombosis	16.40	10.79	4	104562	6	42516763
Decreased appetite	16.40	10.79	355	104211	192782	42323987
Anxiety	16.38	10.79	199	104367	118361	42398408
Frequent bowel movements	16.35	10.79	17	104549	21390	42495379
Hallucination, auditory	16.34	10.79	8	104558	14856	42501913
Intraventricular haemorrhage	16.30	10.79	32	104534	3852	42512917
Crystalluria	16.25	10.79	14	104552	736	42516033
Eye pruritus	16.22	10.79	4	104562	11408	42505361
Amnesia	16.21	10.79	28	104538	28409	42488360
Respiratory gas exchange disorder	16.15	10.79	12	104554	509	42516260
Spontaneous haematoma	16.12	10.79	14	104552	744	42516025
Thoracic haemorrhage	16.10	10.79	9	104557	232	42516537
Herpes simplex reactivation	16.03	10.79	12	104554	515	42516254
Injection site swelling	16.00	10.79	11	104555	16962	42499807
Dehiscence	15.94	10.79	13	104553	633	42516136
Generalised oedema	15.78	10.79	77	104489	15259	42501510
Illness	15.68	10.79	23	104543	24907	42491862
Needle issue	15.56	10.79	52	104514	8675	42508094
Somnolence	15.51	10.79	248	104318	140857	42375912
Periportal sinus dilatation	15.45	10.79	8	104558	176	42516593
Transplant rejection	15.42	10.79	7	104559	13581	42503188
Puncture site haemorrhage	15.41	10.79	10	104556	340	42516429
Paraparesis	15.32	10.79	22	104544	2049	42514720
Bronchiectasis	15.30	10.79	13	104553	18006	42498763
End stage renal disease	15.26	10.79	11	104555	16547	42500222
Splenic lesion	15.25	10.79	10	104556	346	42516423
Tumour lysis syndrome	15.17	10.79	100	104466	22131	42494638
Pain in extremity	15.15	10.79	269	104297	150335	42366434
Hyperthermia	15.05	10.79	66	104500	12508	42504261
Confusional state	15.03	10.79	527	104039	167070	42349699
Foetal heart rate deceleration abnormality	15.03	10.79	12	104554	567	42516202
Spinal subdural haematoma	15.02	10.79	6	104560	70	42516699
Rhinorrhoea	14.96	10.79	35	104531	31759	42485010
Nodule	14.95	10.79	6	104560	12528	42504241
Paresis	14.91	10.79	24	104542	2472	42514297
Small for dates baby	14.87	10.79	37	104529	5226	42511543
Neuralgia	14.85	10.79	25	104541	25622	42491147
White blood cells urine positive	14.83	10.79	18	104548	1423	42515346
Visual impairment	14.82	10.79	55	104511	43058	42473711
Pleural effusion	14.78	10.79	327	104239	96839	42419930
Mucosal haemorrhage	14.71	10.79	20	104546	1770	42514999
Hyperlipasaemia	14.71	10.79	12	104554	585	42516184
Drug interaction	14.67	10.79	798	103768	266201	42250568
Vessel puncture site haematoma	14.64	10.79	6	104560	75	42516694
Acute respiratory distress syndrome	14.64	10.79	125	104441	29983	42486786
Postoperative respiratory failure	14.54	10.79	7	104559	131	42516638
Myasthenia gravis	14.51	10.79	11	104555	16126	42500643
Schizophrenia	14.42	10.79	4	104562	10546	42506223
Arthropathy	14.40	10.79	32	104534	29565	42487204
Injection site erythema	14.37	10.79	17	104549	20178	42496591
Depressed mood	14.29	10.79	22	104544	23362	42493407
Nasal congestion	14.27	10.79	32	104534	29469	42487300
Serotonin syndrome	14.24	10.79	26	104540	25819	42490950
Diffuse alveolar damage	14.24	10.79	24	104542	2568	42514201
Renal embolism	14.21	10.79	7	104559	138	42516631
Lymphopenia	14.12	10.79	96	104470	21467	42495302
Oropharyngeal pain	14.11	10.79	55	104511	42455	42474314
Impaired work ability	14.08	10.79	6	104560	12085	42504684
Blood alkaline phosphatase increased	14.05	10.79	135	104431	33462	42483307
Conductive deafness	14.03	10.79	11	104555	506	42516263
Haemolytic anaemia	14.02	10.79	63	104503	12064	42504705
Carcinoid tumour of the small bowel	14.00	10.79	10	104556	399	42516370
Heart sounds abnormal	13.94	10.79	14	104552	896	42515873
Axillary vein thrombosis	13.92	10.79	9	104557	304	42516465
Ear infection	13.91	10.79	7	104559	12797	42503972
Prothrombin level abnormal	13.85	10.79	6	104560	87	42516682
Herpes zoster	13.75	10.79	49	104517	38828	42477941
Gastric disorder	13.75	10.79	6	104560	11916	42504853
Antibiotic level above therapeutic	13.74	10.79	10	104556	411	42516358
Taste disorder	13.71	10.79	4	104562	10203	42506566
Hypoaldosteronism	13.69	10.79	9	104557	313	42516456
Multiple organ dysfunction syndrome	13.65	10.79	323	104243	96712	42420057
Skin exfoliation	13.64	10.79	54	104512	41499	42475270
Body temperature abnormal	13.63	10.79	14	104552	920	42515849
Spinal epidural haematoma	13.61	10.79	10	104556	417	42516352
Ventricular flutter	13.60	10.79	6	104560	91	42516678
Lip swelling	13.60	10.79	16	104550	19037	42497732
Pulmonary sepsis	13.48	10.79	27	104539	3297	42513472
Coronary artery embolism	13.48	10.79	7	104559	155	42516614
Blood uric acid increased	13.47	10.79	11	104555	15536	42501233
Product monitoring error	13.46	10.79	32	104534	4391	42512378
Abnormal behaviour	13.37	10.79	28	104538	26423	42490346
Arterial thrombosis	13.34	10.79	19	104547	1757	42515012
Varicella virus test positive	13.31	10.79	8	104558	237	42516532
Catheter site oedema	13.29	10.79	5	104561	49	42516720
Tremor	13.27	10.79	163	104403	96766	42420003
Generalised bullous fixed drug eruption	13.20	10.79	10	104556	437	42516332
Catheter site thrombosis	13.20	10.79	7	104559	162	42516607
Vitamin K decreased	13.20	10.79	5	104561	50	42516719
Red blood cell sedimentation rate increased	13.13	10.79	4	104562	9920	42506849
Ischaemic hepatitis	13.09	10.79	21	104545	2156	42514613
Bicytopenia	13.08	10.79	26	104540	3158	42513611
Encephalopathy	13.05	10.79	157	104409	41176	42475593
Neonatal infection	13.00	10.79	10	104556	447	42516322
Jugular vein occlusion	12.97	10.79	3	104563	3	42516766
Cardiac ventricular thrombosis	12.97	10.79	19	104547	1803	42514966
Psychotic symptom	12.96	10.79	22	104544	2368	42514401
Tumour haemorrhage	12.94	10.79	28	104538	3610	42513159
Hypercoagulation	12.88	10.79	17	104549	1462	42515307
Acute encephalitis with refractory, repetitive partial seizures	12.77	10.79	5	104561	55	42516714
Morvan syndrome	12.77	10.79	4	104562	21	42516748
Urticaria	12.76	10.79	118	104448	73918	42442851
Intracardiac thrombus	12.68	10.79	22	104544	2410	42514359
Oesophageal carcinoma	12.66	10.79	4	104562	9692	42507077
Acne	12.66	10.79	9	104557	13635	42503134
Road traffic accident	12.62	10.79	17	104549	19076	42497693
Creatinine renal clearance abnormal	12.58	10.79	9	104557	360	42516409
Product substitution issue	12.52	10.79	6	104560	11284	42505485
Product prescribing error	12.48	10.79	108	104458	26004	42490765
Mitral valve replacement	12.36	10.79	7	104559	185	42516584
Tooth disorder	12.35	10.79	7	104559	11972	42504797
Aortic occlusion	12.33	10.79	7	104559	186	42516583
Hepatic function abnormal	12.31	10.79	75	104491	51492	42465277
Platelet function test abnormal	12.29	10.79	6	104560	116	42516653
Photosensitivity reaction	12.29	10.79	8	104558	12694	42504075
Urinary sediment present	12.25	10.79	8	104558	275	42516494
Visual acuity reduced	12.24	10.79	15	104551	17535	42499234
Drug resistance	12.23	10.79	43	104523	34205	42482564
Hepatic rupture	12.17	10.79	5	104561	63	42516706
Duodenal ulcer	12.17	10.79	61	104505	12218	42504551
Gingival pain	12.03	10.79	3	104563	8491	42508278
Meningorrhagia	12.01	10.79	6	104560	122	42516647
Tri-iodothyronine increased	11.96	10.79	5	104561	66	42516703
Middle ear inflammation	11.90	10.79	7	104559	199	42516570
Fluid retention	11.76	10.79	39	104527	31580	42485189
Bullous impetigo	11.76	10.79	3	104563	6	42516763
Aortic embolus	11.76	10.79	3	104563	6	42516763
Sedation	11.75	10.79	37	104529	30438	42486331
Haematoma infection	11.74	10.79	14	104552	1087	42515682
Asphyxia	11.67	10.79	3	104563	8323	42508446
Brachiocephalic vein thrombosis	11.67	10.79	6	104560	130	42516639
Coagulation test abnormal	11.64	10.79	11	104555	653	42516116
Administration site erythema	11.63	10.79	5	104561	71	42516698
Throat irritation	11.57	10.79	9	104557	13027	42503742
Peripheral artery occlusion	11.52	10.79	18	104548	1808	42514961
Septic pulmonary embolism	11.51	10.79	6	104560	134	42516635
Post transplant lymphoproliferative disorder	11.49	10.79	4	104562	9116	42507653
Renal failure	11.44	10.79	446	104120	143280	42373489
Urethral stenosis	11.41	10.79	13	104553	961	42515808
Therapeutic embolisation	11.40	10.79	8	104558	310	42516459
Cardiac arrest	11.40	10.79	350	104216	108970	42407799
Anaphylactic reaction	11.38	10.79	60	104506	42683	42474086
Vessel puncture site haemorrhage	11.33	10.79	5	104561	76	42516693
Arterial rupture	11.30	10.79	10	104556	545	42516224
Overdose	11.23	10.79	186	104380	105078	42411691
Nephritis allergic	11.20	10.79	11	104555	685	42516084
Pneumobilia	11.19	10.79	6	104560	142	42516627
Antithrombin III deficiency	11.12	10.79	6	104560	144	42516625
Decubitus ulcer	11.06	10.79	53	104513	10424	42506345
Autoimmune disorder	11.06	10.79	21	104545	2466	42514303
Haemostasis	11.04	10.79	6	104560	146	42516623
Blood bilirubin abnormal	11.04	10.79	12	104554	842	42515927
Coronary artery thrombosis	11.04	10.79	20	104546	2266	42514503
Sensory loss	11.03	10.79	33	104533	5191	42511578
Mitral perforation	11.03	10.79	4	104562	35	42516734
Granulocyte count increased	11.02	10.79	9	104557	439	42516330
Red blood cell abnormality	11.02	10.79	9	104557	439	42516330
Vitamin B6 deficiency	10.98	10.79	8	104558	329	42516440
Alopecia	10.97	10.79	36	104530	29240	42487529
Clinical trial participant	10.93	10.79	5	104561	83	42516686
Spinal cord injury cauda equina	10.90	10.79	6	104560	150	42516619
Atrial flutter	10.82	10.79	76	104490	17175	42499594
Knee arthroplasty	10.81	10.79	4	104562	8777	42507992

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Heparin-induced thrombocytopenia	1510.33	10.29	618	197174	10806	110380701
Haematoma	1234.88	10.29	942	196850	57534	110333973
Thrombocytopenia	1087.78	10.29	2108	195684	346777	110044730
Abdominal wall haematoma	827.66	10.29	330	197462	5375	110386132
Shock haemorrhagic	820.23	10.29	545	197247	26702	110364805
Cholestasis	781.49	10.29	756	197036	63762	110327745
Hepatic cytolysis	737.23	10.29	682	197110	54371	110337136
Hepatocellular injury	722.39	10.29	650	197142	49992	110341515
Pulmonary embolism	722.04	10.29	1340	196452	213134	110178373
Retroperitoneal haematoma	700.58	10.29	299	197493	5832	110385675
Anaemia	679.95	10.29	2336	195456	544750	109846757
Acute kidney injury	646.67	10.29	2543	195249	632887	109758620
Drug reaction with eosinophilia and systemic symptoms	624.12	10.29	752	197040	81343	110310164
Retroperitoneal haemorrhage	615.37	10.29	272	197520	5793	110385714
Rash maculo-papular	610.77	10.29	708	197084	73514	110317993
Eosinophilia	580.97	10.29	613	197179	57323	110334184
Deep vein thrombosis	564.95	10.29	947	196845	138940	110252567
Haemorrhage	539.82	10.29	801	196991	105891	110285616
Joint swelling	492.58	10.29	97	197695	442748	109948759
Acute generalised exanthematous pustulosis	479.24	10.29	359	197433	21305	110370202
Haematoma muscle	475.71	10.29	202	197590	3888	110387619
Synovitis	441.88	10.29	10	197782	274082	110117425
Muscle haemorrhage	418.50	10.29	217	197575	6652	110384855
Drug ineffective	412.08	10.29	1374	196418	1519166	108872341
Completed suicide	411.23	10.29	4	197788	242377	110149130
Rheumatoid arthritis	397.94	10.29	38	197754	299575	110091932
Haemoglobin decreased	380.75	10.29	1142	196650	247585	110143922
Haematuria	363.42	10.29	583	197209	82422	110309085
Drug intolerance	352.38	10.29	143	197649	406369	109985138
Pemphigus	349.10	10.29	7	197785	214563	110176944
Arthropathy	348.25	10.29	50	197742	287472	110104035
Weight increased	339.51	10.29	163	197629	419481	109972026
Intra-abdominal haematoma	337.13	10.29	151	197641	3321	110388186
Systemic lupus erythematosus	335.76	10.29	33	197759	254305	110137202
Nasopharyngitis	330.16	10.29	146	197646	394215	109997292
Alopecia	323.20	10.29	124	197668	364629	110026878
Mixed liver injury	319.26	10.29	223	197569	11856	110379651
Therapeutic product effect decreased	311.51	10.29	36	197756	244280	110147227
Neutropenia	311.25	10.29	1411	196381	373209	110018298
Glossodynia	300.53	10.29	26	197766	221978	110169529
Agranulocytosis	294.23	10.29	451	197341	61309	110330198
Premature delivery	292.69	10.29	316	197476	30316	110361191
Abdominal discomfort	290.64	10.29	172	197620	393686	109997821
Arthralgia	288.34	10.29	602	197190	779030	109612477
Fibromyalgia	284.56	10.29	4	197788	170905	110220602
Gastrointestinal haemorrhage	281.10	10.29	789	197003	164729	110226778
Psoriatic arthropathy	269.20	10.29	22	197770	196739	110194768
Pain	266.69	10.29	850	196942	954105	109437402
Irritable bowel syndrome	260.75	10.29	7	197785	164208	110227299
Helicobacter infection	258.36	10.29	17	197775	181860	110209647
Musculoskeletal stiffness	254.77	10.29	91	197701	279731	110111776
Folliculitis	249.44	10.29	12	197780	167641	110223866
Sinusitis	244.85	10.29	112	197680	296576	110094931
Infusion related reaction	240.76	10.29	197	197595	380965	110010542
Cerebral haemorrhage	239.99	10.29	423	197369	64545	110326962
Exposure during pregnancy	238.57	10.29	750	197042	166674	110224833
Hypotension	231.77	10.29	1667	196125	522182	109869325
Toxic skin eruption	230.49	10.29	265	197527	27250	110364257
Drug hypersensitivity	230.46	10.29	284	197508	453806	109937701
Melaena	230.24	10.29	429	197363	68328	110323179
Asthma	230.24	10.29	80	197712	250211	110141296
Duodenal ulcer perforation	229.47	10.29	25	197767	177675	110213832
International normalised ratio increased	227.70	10.29	489	197303	86283	110305224
Headache	226.73	10.29	814	196978	881563	109509944
Therapeutic product effect incomplete	224.81	10.29	61	197731	223744	110167763
Pericarditis	221.46	10.29	59	197733	219055	110172452
Toxicity to various agents	219.15	10.29	325	197467	480230	109911277
Wound	215.52	10.29	75	197717	234362	110157145
Cytokine release syndrome	213.69	10.29	421	197371	69885	110321622
Hypoxia	212.65	10.29	610	197182	128905	110262602
C-reactive protein abnormal	211.85	10.29	4	197788	129691	110261816
Wheezing	208.03	10.29	98	197694	255132	110136375
Swelling	205.31	10.29	195	197597	350846	110040661
Febrile neutropenia	205.19	10.29	1112	196680	315655	110075852
Treatment failure	204.53	10.29	121	197671	277113	110114394
Hypersensitivity	201.48	10.29	256	197536	403742	109987765
Muscle injury	200.45	10.29	13	197779	140794	110250713
Blood cholesterol increased	200.01	10.29	43	197749	184742	110206765
Drug interaction	198.18	10.29	1551	196241	498632	109892875
Drug abuse	188.55	10.29	43	197749	177368	110214139
Discomfort	188.40	10.29	74	197718	214633	110176874
Clostridium test positive	188.06	10.29	156	197636	10737	110380770
Respiratory failure	186.06	10.29	821	196971	214511	110176996
Post procedural haemorrhage	184.39	10.29	180	197612	15332	110376175
Type 2 diabetes mellitus	176.68	10.29	49	197743	177183	110214324
Haematemesis	173.68	10.29	349	197443	58759	110332748
Sepsis	171.08	10.29	1086	196706	326260	110065247
Sleep disorder due to general medical condition, insomnia type	169.61	10.29	4	197788	105639	110285868
Pelvic haematoma	167.32	10.29	65	197727	984	110390523
Hypovolaemic shock	165.51	10.29	165	197627	14418	110377089
Lip dry	163.81	10.29	3	197789	100080	110291427
Bursitis	163.43	10.29	20	197772	129898	110261609
Fatigue	163.25	10.29	1392	196400	1214566	109176941
Haemoperitoneum	162.65	10.29	108	197684	5280	110386227
Product dose omission issue	161.33	10.29	203	197589	321579	110069928
Mobility decreased	160.97	10.29	114	197678	237308	110154199
Leukopenia	156.65	10.29	603	197189	148188	110243319
Insomnia	155.57	10.29	253	197539	360337	110031170
Loss of personal independence in daily activities	152.32	10.29	40	197752	149980	110241527
Contraindicated product administered	152.15	10.29	132	197660	248135	110143372
Arterial haemorrhage	151.49	10.29	91	197701	3728	110387779
Stomatitis	148.94	10.29	158	197634	270084	110121423
Pancytopenia	148.11	10.29	754	197038	208859	110182648
Facet joint syndrome	147.08	10.29	6	197786	96822	110294685
Joint range of motion decreased	145.55	10.29	22	197770	121810	110269697
Alanine aminotransferase increased	145.55	10.29	683	197109	183090	110208417
Hypokalaemia	145.18	10.29	679	197113	181769	110209738
Dry mouth	145.01	10.29	89	197703	199859	110191648
Ill-defined disorder	139.35	10.29	53	197739	156800	110234707
Migraine	138.17	10.29	67	197725	171585	110219922
Thrombosis	137.83	10.29	468	197324	108194	110283313
Haemorrhage intracranial	137.17	10.29	211	197581	28758	110362749
Atrial fibrillation	135.88	10.29	787	197005	228855	110162652
Subdural haematoma	135.44	10.29	238	197554	36216	110355291
Malaise	134.57	10.29	681	197111	671138	109720369
Bullous haemorrhagic dermatosis	133.33	10.29	42	197750	325	110391182
Transaminases increased	128.65	10.29	323	197469	63067	110328440
International normalised ratio decreased	127.93	10.29	111	197681	8125	110383382
Musculoskeletal pain	127.88	10.29	85	197707	182938	110208569
Peripheral swelling	125.90	10.29	341	197451	403693	109987814
Thrombocytosis	125.65	10.29	122	197670	10322	110381185
Blood loss anaemia	125.41	10.29	158	197634	17867	110373640
Memory impairment	123.99	10.29	102	197690	196842	110194665
Upper gastrointestinal haemorrhage	123.08	10.29	275	197517	49821	110341686
Embolism	121.72	10.29	148	197644	16141	110375366
Renal failure	120.97	10.29	756	197036	225818	110165689
Osteoarthritis	119.47	10.29	91	197701	182532	110208975
Septic shock	117.87	10.29	576	197216	156952	110234555
Depression	117.85	10.29	244	197548	317091	110074416
Intentional product use issue	117.47	10.29	163	197629	247743	110143764
Ischaemic stroke	116.90	10.29	240	197552	41023	110350484
Pyrexia	116.51	10.29	2253	195539	896012	109495495
Muscle spasms	116.38	10.29	199	197593	277958	110113549
Purpura	115.99	10.29	178	197614	24210	110367297
Cerebral haematoma	114.92	10.29	112	197680	9520	110381987
Hepatitis acute	114.22	10.29	154	197638	18612	110372895
Product use issue	113.78	10.29	242	197550	311453	110080054
Dizziness	113.46	10.29	757	197035	697436	109694071
Ecchymosis	112.80	10.29	147	197645	17191	110374316
Gastrointestinal disorder	112.74	10.29	161	197631	241791	110149716
Electrocardiogram QT prolonged	112.55	10.29	439	197353	108521	110282986
Psoriasis	112.12	10.29	55	197737	139938	110251569
Toxic epidermal necrolysis	111.94	10.29	286	197506	56441	110335066
Sleep disorder	111.84	10.29	114	197678	198530	110192977
Tachycardia	111.64	10.29	741	197051	225904	110165603
Hypoaesthesia	111.37	10.29	248	197544	313975	110077532
Lower respiratory tract infection	111.08	10.29	164	197628	242942	110148565
Compartment syndrome	109.08	10.29	88	197704	5822	110385685
Intentional product misuse	108.29	10.29	51	197741	132853	110258654
Post procedural haematoma	107.58	10.29	64	197728	2575	110388932
Coagulopathy	106.65	10.29	230	197562	40681	110350826
Road traffic accident	106.45	10.29	30	197762	107368	110284139
Vascular device infection	105.87	10.29	139	197653	16373	110375134
Gastric haemorrhage	105.20	10.29	136	197656	15779	110375728
Arthritis	104.00	10.29	88	197704	167498	110224009
Cholestatic liver injury	103.79	10.29	94	197698	7282	110384225
Gamma-glutamyltransferase increased	102.75	10.29	291	197501	61018	110330489
Erysipelas	102.32	10.29	122	197670	13036	110378471
Hepatic enzyme increased	102.08	10.29	268	197524	320624	110070883
Intra-abdominal haemorrhage	101.70	10.29	81	197711	5261	110386246
COVID-19 pneumonia	99.34	10.29	211	197581	36932	110354575
Epistaxis	99.17	10.29	479	197313	129893	110261614
Intentional overdose	98.84	10.29	57	197735	132444	110259063
Respiratory distress	98.45	10.29	309	197483	68565	110322942
Haemarthrosis	98.45	10.29	91	197701	7238	110384269
Adverse drug reaction	98.30	10.29	33	197759	105526	110285981
Extradural haematoma	98.02	10.29	66	197726	3303	110388204
Pleural effusion	98.00	10.29	598	197194	177111	110214396
Acute respiratory failure	97.95	10.29	327	197465	74933	110316574
Rash morbilliform	97.77	10.29	94	197698	7857	110383650
Hypertransaminasaemia	97.51	10.29	164	197628	24091	110367416
COVID-19 treatment	96.87	10.29	35	197757	428	110391079
Computerised tomogram thorax abnormal	96.61	10.29	61	197731	2734	110388773
Hypercholesterolaemia	96.53	10.29	22	197770	90815	110300692
Aspartate aminotransferase increased	95.14	10.29	549	197243	159387	110232120
Sciatica	95.00	10.29	24	197768	92375	110299132
Hepatitis cholestatic	94.73	10.29	136	197656	17430	110374077
Peripheral venous disease	94.27	10.29	18	197774	84099	110307408
Dermatitis bullous	93.48	10.29	135	197657	17394	110374113
Paraplegia	93.17	10.29	82	197710	6118	110385389
Urticaria	92.75	10.29	278	197514	318579	110072928
Inflammation	91.59	10.29	127	197665	193111	110198396
Night sweats	89.90	10.29	65	197727	133918	110257589
Petechiae	88.92	10.29	154	197638	23163	110368344
Computerised tomogram thorax	88.92	10.29	34	197758	492	110391015
Injection site haematoma	87.39	10.29	73	197719	5073	110386434
Haemorrhagic stroke	86.74	10.29	115	197677	13674	110377833
Spontaneous haematoma	86.37	10.29	50	197742	1911	110389596
Haematocrit decreased	85.80	10.29	287	197505	65830	110325677
Pulmonary fibrosis	84.93	10.29	38	197754	102004	110289503
Chest wall haematoma	84.80	10.29	33	197759	502	110391005
Blepharospasm	84.66	10.29	3	197789	54848	110336659
Haemodynamic instability	84.47	10.29	149	197643	22739	110368768
Haemoptysis	84.12	10.29	300	197492	71054	110320453
Oliguria	82.92	10.29	132	197660	18525	110372982
Feeling abnormal	82.45	10.29	122	197670	180589	110210918
Heparin-induced thrombocytopenia test	81.89	10.29	26	197766	207	110391300
Multiple organ dysfunction syndrome	81.43	10.29	507	197285	151203	110240304
Impaired healing	81.10	10.29	142	197650	196575	110194932
Injury associated with device	80.26	10.29	65	197727	4324	110387183
Sleep disorder due to a general medical condition	79.92	10.29	3	197789	52109	110339398
Blood pressure increased	78.98	10.29	220	197572	258153	110133354
Weight decreased	78.70	10.29	502	197290	467555	109923952
Spinal epidural haematoma	78.69	10.29	45	197747	1680	110389827
Blood pressure fluctuation	77.77	10.29	19	197773	74805	110316702
Blister	77.67	10.29	183	197609	227193	110164314
Red blood cell sedimentation rate increased	77.36	10.29	22	197770	78280	110313227
Gait inability	77.05	10.29	78	197714	136298	110255209
Pain in extremity	76.12	10.29	534	197258	486584	109904923
Inappropriate schedule of product administration	76.05	10.29	156	197636	203481	110188026
Cell death	76.04	10.29	71	197721	5720	110385787
Vascular purpura	75.71	10.29	59	197733	3712	110387795
Labelled drug-drug interaction medication error	75.53	10.29	164	197628	29138	110362369
Coagulation time prolonged	75.10	10.29	53	197739	2864	110388643
Cardiac arrest	74.90	10.29	605	197187	196148	110195359
Lower limb fracture	74.76	10.29	21	197771	75327	110316180
Adverse event	74.03	10.29	52	197740	108757	110282750
Prescribed overdose	73.86	10.29	32	197760	87549	110303958
Obesity	73.46	10.29	57	197735	113294	110278213
Gastrooesophageal reflux disease	73.21	10.29	131	197661	179845	110211662
Ovarian hyperstimulation syndrome	72.87	10.29	67	197725	5293	110386214
Tachyarrhythmia	71.61	10.29	81	197711	8180	110383327
Adrenal haemorrhage	71.53	10.29	33	197759	779	110390728
Venous thrombosis	71.37	10.29	82	197710	8423	110383084
Fibrin D dimer increased	71.21	10.29	88	197704	9757	110381750
Ear infection	71.20	10.29	13	197779	62719	110328788
Blood alkaline phosphatase increased	70.98	10.29	283	197509	70652	110320855
Nail disorder	70.26	10.29	10	197782	57925	110333582
Prothrombin time prolonged	69.77	10.29	117	197675	17144	110374363
Seroma	69.23	10.29	53	197739	3248	110388259
Frequent bowel movements	68.81	10.29	21	197771	71369	110320138
Encephalopathy	68.39	10.29	307	197485	80748	110310759
Amnesia	68.32	10.29	53	197739	105355	110286152
Pneumonitis	67.70	10.29	294	197498	76237	110315270
Injury	66.87	10.29	135	197657	177130	110214377
Heparin-induced thrombocytopenia test positive	66.63	10.29	20	197772	129	110391378
Haemorrhagic transformation stroke	66.43	10.29	50	197742	2987	110388520
Atelectasis	66.21	10.29	179	197613	36533	110354974
Taste disorder	65.29	10.29	18	197774	65369	110326138
International normalised ratio abnormal	65	10.29	68	197724	6289	110385218
Wound infection pseudomonas	64.85	10.29	45	197747	2366	110389141
Hyponatraemia	64.67	10.29	634	197158	217019	110174488
Hepatitis	64.29	10.29	325	197467	89729	110301778
Spinal cord haemorrhage	64.04	10.29	28	197764	580	110390927
Sinus bradycardia	63.81	10.29	154	197638	29329	110362178
Lymphopenia	63.76	10.29	187	197605	39983	110351524
Lymphatic fistula	62.89	10.29	37	197755	1458	110390049
Femoral hernia incarcerated	62.57	10.29	37	197755	1472	110390035
Abdominal pain upper	62.53	10.29	367	197425	348744	110042763
Off label use	62.46	10.29	3278	194514	1496907	108894600
Symmetrical drug-related intertriginous and flexural exanthema	62.09	10.29	40	197752	1857	110389650
Coeliac disease	61.41	10.29	4	197788	43183	110348324
Wound dehiscence	60.56	10.29	73	197719	7889	110383618
Myelosuppression	60.43	10.29	48	197744	94292	110297215
Therapy non-responder	60.02	10.29	119	197673	157188	110234319
Duodenal ulcer haemorrhage	60.01	10.29	73	197719	7964	110383543
Gait disturbance	59.64	10.29	275	197517	277933	110113574
Thrombophlebitis	59.38	10.29	71	197721	7608	110383899
Spinal cord haematoma	59.26	10.29	22	197770	292	110391215
Bradycardia	59.07	10.29	478	197314	155039	110236468
Urinary retention	58.84	10.29	264	197528	69419	110322088
Tachypnoea	58.38	10.29	179	197613	39216	110352291
Neck pain	58.26	10.29	81	197711	123049	110268458
Autoimmune heparin-induced thrombocytopenia	57.79	10.29	15	197777	51	110391456
Haemothorax	57.67	10.29	67	197725	6964	110384543
Lupus-like syndrome	57.36	10.29	4	197788	40788	110350719
Hypertension	57.00	10.29	610	197182	509474	109882033
Vascular stent thrombosis	56.54	10.29	52	197740	4109	110387398
Illness	56.26	10.29	39	197753	82132	110309375
Pancreatic steatosis	56.16	10.29	37	197755	1785	110389722
Jugular vein thrombosis	56.13	10.29	58	197734	5287	110386220
Back injury	55.60	10.29	9	197783	47390	110344117
Hyperkalaemia	55.21	10.29	424	197368	135372	110256135
Suicidal ideation	55.06	10.29	52	197740	93885	110297622
Disorientation	54.69	10.29	261	197531	70410	110321097
Wound infection	54.69	10.29	55	197737	96410	110295097
Blood creatinine increased	53.96	10.29	532	197260	182357	110209150
Autoimmune disorder	53.53	10.29	25	197767	65458	110326049
Subcutaneous haematoma	53.49	10.29	44	197748	2992	110388515
Influenza	53.15	10.29	142	197650	168959	110222548
Anxiety	53.03	10.29	380	197412	344698	110046809
Anticoagulation drug level below therapeutic	52.93	10.29	35	197757	1699	110389808
Nasal congestion	52.40	10.29	59	197733	98223	110293284
Escherichia infection	52.18	10.29	125	197667	23691	110367816
Hypofibrinogenaemia	52.02	10.29	40	197752	2467	110389040
Therapeutic response decreased	51.38	10.29	58	197734	96441	110295066
Onychomycosis	50.81	10.29	5	197787	38526	110352981
Splenic infarction	50.58	10.29	50	197742	4324	110387183
Vascular pseudoaneurysm	50.51	10.29	49	197743	4141	110387366
Paraesthesia	50.41	10.29	289	197503	276232	110115275
Dyspepsia	50.27	10.29	174	197618	190791	110200716
Laryngitis	49.87	10.29	8	197784	42403	110349104
Acute respiratory distress syndrome	49.86	10.29	208	197584	52990	110338517
Haemolytic anaemia	49.33	10.29	113	197679	20807	110370700
Rhinorrhoea	49.11	10.29	67	197725	102599	110288908
Anuria	48.30	10.29	123	197669	24218	110367289
Stress	48.16	10.29	71	197721	105277	110286230
Hypercoagulation	48.01	10.29	43	197749	3283	110388224
Faecaloma	47.38	10.29	91	197701	14817	110376690
Finger deformity	47.25	10.29	3	197789	33089	110358418
Foetal growth restriction	47.16	10.29	41	197751	3009	110388498
Knee arthroplasty	46.94	10.29	29	197763	64919	110326588
Cardio-respiratory arrest	46.70	10.29	361	197431	115475	110276032
Hepatic cyst	46.04	10.29	63	197729	7720	110383787
Product prescribing error	46.01	10.29	198	197594	51133	110340374
Infection	45.94	10.29	420	197372	361780	110029727
General physical health deterioration	45.54	10.29	1038	196754	424257	109967250
Plasma cell myeloma	45.53	10.29	228	197564	62708	110328799
Palpitations	45.41	10.29	140	197652	159072	110232435
Liver injury	45.26	10.29	129	197663	150284	110241223
Product quality issue	45.06	10.29	43	197749	77256	110314251
Procedural haemorrhage	44.99	10.29	52	197740	5375	110386132
Rash	44.80	10.29	1122	196670	819842	109571665
Hip arthroplasty	44.57	10.29	22	197770	55791	110335716
Device expulsion	43.52	10.29	3	197789	30888	110360619
Aplastic anaemia	43.31	10.29	118	197674	24190	110367317
Generalised oedema	43.18	10.29	137	197655	30567	110360940
Dehydration	43.07	10.29	721	197071	278790	110112717
Long QT syndrome	42.69	10.29	58	197734	7060	110384447
Accidental exposure to product	42.60	10.29	18	197774	49990	110341517
Hepatic cirrhosis	42.57	10.29	35	197757	67591	110323916
Ear pain	42.47	10.29	21	197771	53205	110338302
Suture rupture	41.93	10.29	22	197770	691	110390816
Pruritus	41.86	10.29	760	197032	580800	109810707
Spinal cord compression	41.50	10.29	59	197733	7493	110384014
Intraventricular haemorrhage	41.08	10.29	50	197742	5457	110386050
Joint stiffness	40.86	10.29	36	197756	67207	110324300
Urinary tract infection pseudomonal	40.83	10.29	33	197759	2189	110389318
Syncope	40.77	10.29	547	197245	201989	110189518
Injection site erythema	40.63	10.29	66	197726	94110	110297397
Foot deformity	40.42	10.29	18	197774	48462	110343045
Rash pustular	40.39	10.29	78	197714	12751	110378756
Abdominal mass	40.39	10.29	47	197745	4894	110386613
Spinal epidural haemorrhage	40.33	10.29	17	197775	321	110391186
Throat irritation	39.98	10.29	23	197769	53529	110337978
Stevens-Johnson syndrome	39.83	10.29	178	197614	46723	110344784
Drug dependence	39.51	10.29	20	197772	50000	110341507
Myalgia	39.15	10.29	235	197557	222146	110169361
Injection site swelling	38.87	10.29	32	197760	61758	110329749
Vena cava thrombosis	38.67	10.29	39	197753	3455	110388052
Wound haemorrhage	38.61	10.29	45	197747	4693	110386814
Heart rate decreased	38.59	10.29	55	197737	82701	110308806
Exostosis	38.42	10.29	17	197775	45939	110345568
Cerebrovascular accident	38.32	10.29	494	197298	180790	110210717
Rectal haemorrhage	38.01	10.29	354	197438	119479	110272028
Peripheral artery thrombosis	37.54	10.29	41	197751	3983	110387524
Pulmonary interstitial emphysema syndrome	37.44	10.29	19	197773	556	110390951
Vision blurred	37.11	10.29	113	197679	128909	110262598
Suicide attempt	37.09	10.29	81	197711	103313	110288194
Cerebral venous sinus thrombosis	37.06	10.29	35	197757	2860	110388647
Epidural haemorrhage	37.05	10.29	17	197775	396	110391111
Prothrombin time abnormal	37.02	10.29	25	197767	1257	110390250
Peripheral ischaemia	37.00	10.29	69	197723	10989	110380518
Cataract	36.89	10.29	53	197739	79432	110312075
Eye pruritus	36.75	10.29	7	197785	32768	110358739
Generalised bullous fixed drug eruption	36.75	10.29	21	197771	783	110390724
Product monitoring error	36.74	10.29	61	197731	8866	110382641
Liver function test abnormal	36.71	10.29	230	197562	68720	110322787
Cardiac failure	36.64	10.29	504	197288	187122	110204385
Hypercapnic coma	36.43	10.29	18	197774	497	110391010
Visual impairment	36.38	10.29	121	197671	134307	110257200
Dermatitis exfoliative generalised	36.14	10.29	68	197724	10904	110380603
Thrombosis in device	35.96	10.29	46	197746	5281	110386226
Swelling face	35.94	10.29	69	197723	92252	110299255
Liver disorder	35.84	10.29	132	197660	142111	110249396
Klebsiella infection	35.52	10.29	97	197695	19912	110371595
Hemianopia homonymous	35.20	10.29	26	197766	1509	110389998
Acetabulum fracture	35.12	10.29	22	197770	972	110390535
Subarachnoid haemorrhage	35.10	10.29	125	197667	29577	110361930
Embolism venous	34.89	10.29	44	197748	4979	110386528
Anti factor V antibody	34.47	10.29	15	197777	307	110391200
Placental insufficiency	34.45	10.29	24	197768	1270	110390237
Alveolitis	34.25	10.29	41	197751	4398	110387109
Tumour lysis syndrome	34.18	10.29	127	197665	30674	110360833
Catheter site haemorrhage	33.89	10.29	47	197745	5833	110385674
Groin pain	33.83	10.29	81	197711	15347	110376160
Eye irritation	33.79	10.29	9	197783	33443	110358064
Fluid retention	33.73	10.29	74	197718	94233	110297274
Blood blister	33.72	10.29	38	197754	3821	110387686
Peritoneal haematoma	33.72	10.29	14	197778	254	110391253
Pulmonary haemorrhage	33.53	10.29	84	197708	16372	110375135
Crystalluria	33.45	10.29	24	197768	1331	110390176
Alveolar lung disease	33.45	10.29	19	197773	700	110390807
Cerebral artery occlusion	33.44	10.29	28	197764	1952	110389555
Wrong technique in product usage process	33.38	10.29	66	197726	87282	110304225
Cyanosis	33.31	10.29	123	197669	29618	110361889
Abortion induced	33.27	10.29	55	197737	7964	110383543
Diverticulum intestinal	33.00	10.29	68	197724	11651	110379856
Contusion	32.97	10.29	263	197529	233098	110158409
Hospitalisation	32.85	10.29	137	197655	142356	110249151
Influenza like illness	32.76	10.29	68	197724	88344	110303163
Abdominal wall haemorrhage	32.64	10.29	19	197773	734	110390773
Acute myocardial infarction	32.61	10.29	259	197533	83518	110307989
Injection site reaction	32.59	10.29	69	197723	89001	110302506
Nasal mucosal disorder	32.57	10.29	27	197765	1856	110389651
Systemic inflammatory response syndrome	32.48	10.29	72	197720	12971	110378536
Pulmonary hypertension	32.45	10.29	189	197603	55031	110336476
Diabetes mellitus	32.33	10.29	82	197710	99299	110292208
Neonatal infection	32.09	10.29	8	197784	22	110391485
Splenic rupture	32.09	10.29	31	197761	2606	110388901
Underdose	31.91	10.29	40	197752	63514	110327993
Caesarean section	31.88	10.29	74	197718	13743	110377764
Venous thrombosis limb	31.73	10.29	43	197749	5222	110386285
Activated partial thromboplastin time prolonged	31.63	10.29	100	197692	22268	110369239
Renal tubular necrosis	31.63	10.29	123	197669	30352	110361155
Sinobronchitis	31.60	10.29	16	197776	466	110391041
Ureteric compression	31.59	10.29	14	197778	300	110391207
Sneezing	31.57	10.29	9	197783	31975	110359532
Blood pressure systolic increased	31.46	10.29	63	197729	82928	110308579
Obstructive airways disorder	31.46	10.29	22	197770	46127	110345380
Premature baby	31.33	10.29	41	197751	4814	110386693
Therapeutic embolisation	31.31	10.29	17	197775	573	110390934
Circulatory collapse	31.27	10.29	156	197636	42837	110348670
Oropharyngeal pain	31.22	10.29	130	197662	135146	110256361
Protein deficiency	31.22	10.29	15	197777	389	110391118
Spinal subdural haematoma	31.21	10.29	13	197779	238	110391269
Skin necrosis	31.18	10.29	97	197695	21415	110370092
Pituitary haemorrhage	31.08	10.29	14	197778	312	110391195
Leukocytosis	30.83	10.29	183	197609	53645	110337862
Blood pressure systolic abnormal	30.82	10.29	4	197788	24846	110366661
Nail bed inflammation	30.81	10.29	27	197765	2003	110389504
Inflammatory marker increased	30.69	10.29	75	197717	14394	110377113
Intracranial pressure increased	30.69	10.29	62	197730	10473	110381034
Hypocoagulable state	30.44	10.29	30	197762	2585	110388922
Catheter site haematoma	30.43	10.29	15	197777	412	110391095
Drug withdrawal syndrome neonatal	30.32	10.29	14	197778	331	110391176
Pre-eclampsia	30.24	10.29	55	197737	8595	110382912
Blood pressure diastolic abnormal	30.06	10.29	5	197787	25810	110365697
Empyema	29.85	10.29	43	197749	5527	110385980
Adverse reaction	29.82	10.29	8	197784	29586	110361921
Maternal exposure during pregnancy	29.76	10.29	630	197162	254253	110137254
Pseudomonal sepsis	29.72	10.29	56	197736	8990	110382517
Oedema	29.50	10.29	237	197555	209739	110181768
Intracranial haematoma	29.47	10.29	20	197772	1014	110390493
Shock	29.31	10.29	180	197612	53408	110338099
Lower gastrointestinal haemorrhage	29.28	10.29	86	197706	18400	110373107
Cardiac valve replacement complication	29.20	10.29	12	197780	212	110391295
Vaginal haemorrhage	29.18	10.29	105	197687	24969	110366538
Device related infection	29.17	10.29	144	197648	39375	110352132
Polyneuropathy	29.09	10.29	124	197668	31888	110359619
Aortic arteriosclerosis	29.08	10.29	62	197730	10876	110380631
Hypochromic anaemia	28.80	10.29	32	197760	3169	110388338
Poisoning deliberate	28.74	10.29	6	197786	26325	110365182
Acidosis	28.51	10.29	97	197695	22434	110369073
Bronchial haemorrhage	28.50	10.29	22	197770	1365	110390142
Coronary artery thrombosis	28.45	10.29	32	197760	3212	110388295
Subclavian vein thrombosis	28.43	10.29	30	197762	2802	110388705
Postpartum haemorrhage	28.42	10.29	25	197767	1864	110389643
Aortic valve stenosis	28.32	10.29	45	197747	6305	110385202
Protein total decreased	28.12	10.29	61	197731	10829	110380678
Scrotal haematoma	28.09	10.29	9	197783	74	110391433
Pyelocaliectasis	28.04	10.29	20	197772	1099	110390408
Electrocardiogram ST segment elevation	28.00	10.29	55	197737	9105	110382402
Injection site thrombosis	27.99	10.29	11	197781	172	110391335
Hyperglycaemia	27.81	10.29	253	197539	84837	110306670
Platelet count decreased	27.69	10.29	572	197220	229871	110161636
Antiphospholipid syndrome	27.62	10.29	28	197764	2495	110389012
HELLP syndrome	27.51	10.29	18	197774	858	110390649
Splenic necrosis	27.31	10.29	11	197781	184	110391323
Intestinal ischaemia	27.30	10.29	77	197715	16102	110375405
Immunodeficiency	27.16	10.29	18	197774	38820	110352687
Small intestinal obstruction	27.16	10.29	122	197670	32091	110359416
Pseudomonas infection	26.96	10.29	110	197682	27743	110363764
Chest discomfort	26.89	10.29	191	197601	173657	110217850
Brain herniation	26.83	10.29	53	197739	8810	110382697
Premature labour	26.75	10.29	54	197738	9118	110382389
Pulmonary infarction	26.70	10.29	35	197757	4116	110387391
Malnutrition	26.62	10.29	108	197684	27171	110364336
Colitis ulcerative	26.61	10.29	62	197730	77301	110314206
Foetal heart rate abnormal	26.56	10.29	16	197776	659	110390848
Blood bilirubin increased	26.43	10.29	229	197563	75743	110315764
Bicytopenia	26.41	10.29	45	197747	6679	110384828
Pneumonia	26.37	10.29	1863	195929	874851	109516656
Herpes zoster	26.37	10.29	102	197690	108277	110283230
Upper respiratory tract infection	26.27	10.29	133	197659	131195	110260312
Patient restraint	26.10	10.29	9	197783	95	110391412
Cutaneous vasculitis	25.96	10.29	65	197727	12664	110378843
Intracardiac thrombus	25.93	10.29	35	197757	4233	110387274
Hepatic haematoma	25.93	10.29	18	197774	947	110390560
Schizophrenia	25.93	10.29	4	197788	21822	110369685
Sinus congestion	25.88	10.29	11	197781	30448	110361059
Sudden death	25.75	10.29	99	197693	24296	110367211
Renal infarct	25.61	10.29	31	197761	3364	110388143
Disability	25.55	10.29	11	197781	30212	110361295
Bronchiectasis	25.41	10.29	17	197775	36476	110355031
Dermatitis exfoliative	25.34	10.29	60	197732	11287	110380220
Peripheral nerve injury	25.33	10.29	19	197773	1129	110390378
Immobilisation prolonged	25.29	10.29	10	197782	159	110391348
Atrial flutter	25.24	10.29	98	197694	24164	110367343
Erythrodermic psoriasis	25.16	10.29	24	197768	1986	110389521
Necrosis	25.13	10.29	60	197732	11346	110380161
Adrenal cortex necrosis	24.98	10.29	7	197785	34	110391473
Cleft palate	24.93	10.29	13	197779	403	110391104
Hypercapnia	24.91	10.29	59	197733	11100	110380407
Supraventricular tachycardia	24.88	10.29	98	197694	24324	110367183
Duodenal ulcer	24.68	10.29	84	197708	19430	110372077
Jaundice	24.65	10.29	186	197606	59050	110332457
Maternal exposure timing unspecified	24.62	10.29	4	197788	21009	110370498
Vessel puncture site haematoma	24.59	10.29	11	197781	241	110391266
Hypernatraemia	24.55	10.29	79	197713	17754	110373753
Sinus disorder	24.51	10.29	14	197778	32714	110358793
Product dose omission in error	24.37	10.29	6	197786	23506	110368001
Cystitis radiation	24.35	10.29	11	197781	247	110391260
Hepatic failure	24.33	10.29	208	197584	68531	110322976
Vitamin K deficiency	24.33	10.29	17	197775	904	110390603
Incision site haematoma	24.21	10.29	10	197782	179	110391328
Acne	24.17	10.29	15	197777	33505	110358002
Pelvic haemorrhage	24.11	10.29	10	197782	181	110391326
Streptococcal sepsis	24.09	10.29	37	197755	5035	110386472
Coronary artery embolism	24.07	10.29	12	197780	338	110391169
Post procedural complication	24.02	10.29	103	197689	26555	110364952
Hypersensitivity myocarditis	23.97	10.29	12	197780	341	110391166
Gastric disorder	23.96	10.29	15	197777	33342	110358165
Premature separation of placenta	23.95	10.29	21	197771	1559	110389948
Clostridium difficile colitis	23.91	10.29	147	197645	43631	110347876
Soft tissue infection	23.90	10.29	37	197755	5070	110386437
Chills	23.87	10.29	476	197316	190104	110201403
Anticoagulation drug level above therapeutic	23.73	10.29	35	197757	4595	110386912
Splenic haemorrhage	23.70	10.29	16	197776	804	110390703
Factor Xa activity increased	23.68	10.29	6	197786	18	110391489
Eye disorder	23.68	10.29	11	197781	28895	110362612
Tricuspid valve incompetence	23.68	10.29	95	197697	23778	110367729
Urosepsis	23.52	10.29	113	197679	30562	110360945
Erythema multiforme	23.42	10.29	87	197705	21010	110370497
Impaired work ability	23.33	10.29	9	197783	26410	110365097
Activated partial thromboplastin time abnormal	23.19	10.29	12	197780	366	110391141
Chronic sinusitis	23.07	10.29	8	197784	25076	110366431
Walking aid user	23.06	10.29	8	197784	25067	110366440
Phlebitis	23.03	10.29	53	197739	9788	110381719
Hyperlipasaemia	22.99	10.29	20	197772	1469	110390038
Injection site pruritus	22.98	10.29	35	197757	51223	110340284
Jaundice neonatal	22.97	10.29	10	197782	205	110391302
Puncture site haemorrhage	22.89	10.29	15	197777	717	110390790
Eosinophilic pneumonia	22.83	10.29	44	197748	7183	110384324
Metastases to central nervous system	22.79	10.29	91	197701	22726	110368781
Excessive eye blinking	22.79	10.29	22	197770	1848	110389659
Pneumonia acinetobacter	22.75	10.29	12	197780	381	110391126
Arterial thrombosis	22.75	10.29	28	197764	3091	110388416
Aphasia	22.75	10.29	182	197610	58815	110332692
Factor XIII deficiency	22.74	10.29	8	197784	90	110391417
Brain oedema	22.73	10.29	113	197679	30985	110360522
Full blood count abnormal	22.60	10.29	41	197751	56011	110335496
Cardiac ventricular thrombosis	22.55	10.29	28	197764	3119	110388388
Brain compression	22.36	10.29	15	197777	746	110390761
Sputum discoloured	22.33	10.29	11	197781	27934	110363573
Dry eye	22.33	10.29	41	197751	55752	110335755
Ischaemic hepatitis	22.21	10.29	34	197758	4614	110386893
Skin candida	22.20	10.29	24	197768	2304	110389203
Anti factor X activity increased	22.20	10.29	8	197784	97	110391410
Hyperthermia	22.19	10.29	86	197706	21186	110370321
Dermatitis atopic	22.06	10.29	9	197783	25532	110365975
Respiratory tract congestion	21.99	10.29	14	197778	30843	110360664
Febrile infection	21.91	10.29	33	197759	4415	110387092
Mucosal haemorrhage	21.85	10.29	27	197765	2993	110388514
Nodule	21.66	10.29	16	197776	32615	110358892
Intestinal infarction	21.66	10.29	19	197773	1411	110390096
Vaccination site reaction	21.64	10.29	10	197782	237	110391270
Hallucination, visual	21.64	10.29	133	197659	39472	110352035
Hypoaldosteronism	21.63	10.29	14	197778	655	110390852
Pulmonary sepsis	21.63	10.29	36	197756	5242	110386265
Uveitis	21.63	10.29	6	197786	21704	110369803
Basal ganglion degeneration	21.58	10.29	12	197780	424	110391083
Neuromyotonia	21.56	10.29	8	197784	106	110391401
Splenic haematoma	21.55	10.29	11	197781	326	110391181
Coma	21.55	10.29	313	197479	117556	110273951
Large intestine perforation	21.40	10.29	72	197720	16557	110374950
Osteoma	21.36	10.29	8	197784	109	110391398
Adenocarcinoma of colon	21.28	10.29	39	197753	6129	110385378
Intra-abdominal fluid collection	21.26	10.29	30	197762	3784	110387723
Osteoporosis	21.22	10.29	82	197710	87070	110304437
Peptic ulcer perforation	21.13	10.29	15	197777	818	110390689
Hepatic infarction	21.12	10.29	16	197776	965	110390542
Device related sepsis	21.09	10.29	44	197748	7603	110383904
Cardiogenic shock	21.09	10.29	175	197617	57163	110334344
Prescribed underdose	21.02	10.29	54	197738	65120	110326387
Decubitus ulcer	20.91	10.29	76	197716	18160	110373347
Subdural haemorrhage	20.80	10.29	40	197752	6518	110384989
Rash erythematous	20.80	10.29	231	197561	81601	110309906
Inguinal hernia	20.79	10.29	44	197748	7681	110383826
Muscular weakness	20.69	10.29	316	197476	248152	110143355
Renal injury	20.63	10.29	77	197715	18636	110372871
Epidermolysis	20.60	10.29	17	197775	1161	110390346
Hyperleukocytosis	20.59	10.29	28	197764	3411	110388096
Left ventricular dysfunction	20.58	10.29	90	197702	23403	110368104
Pulmonary thrombosis	20.55	10.29	63	197729	13800	110377707
Ocular hyperaemia	20.49	10.29	24	197768	39262	110352245
Foetal exposure during pregnancy	20.49	10.29	43	197749	7462	110384045
Tumour haemorrhage	20.47	10.29	35	197757	5210	110386297
Condition aggravated	20.46	10.29	1090	196702	733746	109657761
Bladder tamponade	20.42	10.29	14	197778	722	110390785
Foetal monitoring abnormal	20.30	10.29	9	197783	193	110391314
Cardiac tamponade	20.25	10.29	55	197737	11252	110380255
Thoracic haemorrhage	20.24	10.29	10	197782	276	110391231
Bronchopleural fistula	20.20	10.29	15	197777	878	110390629
Needle issue	20.16	10.29	74	197718	17766	110373741
Postoperative wound infection	20.09	10.29	68	197724	15685	110375822
Right ventricular dilatation	20.00	10.29	23	197769	2364	110389143
Target skin lesion	19.98	10.29	10	197782	284	110391223
Splenic cyst	19.95	10.29	10	197782	285	110391222
Anticoagulant-related nephropathy	19.92	10.29	9	197783	202	110391305
Axillary vein thrombosis	19.91	10.29	14	197778	752	110390755
Staphylococcal infection	19.91	10.29	202	197590	69742	110321765
Purple glove syndrome	19.88	10.29	10	197782	287	110391220
Dry skin	19.87	10.29	112	197680	107541	110283966
Blood pressure diastolic decreased	19.73	10.29	21	197771	35864	110355643
Renal embolism	19.72	10.29	9	197783	207	110391300
Breast cancer	19.62	10.29	24	197768	38518	110352989
Musculoskeletal disorder	19.56	10.29	8	197784	22656	110368851
Pallor	19.53	10.29	170	197622	56297	110335210
Incision site haemorrhage	19.53	10.29	16	197776	1082	110390425
Quadriplegia	19.45	10.29	30	197762	4097	110387410
Neurological decompensation	19.45	10.29	40	197752	6843	110384664
Postoperative respiratory failure	19.37	10.29	9	197783	216	110391291
Hyperbilirubinaemia	19.35	10.29	107	197685	30564	110360943
Myocardial infarction	19.35	10.29	465	197327	191618	110199889
Tenosynovitis	19.31	10.29	3	197789	16280	110375227
Pericardial haemorrhage	19.30	10.29	34	197758	5183	110386324
Gastritis	19.27	10.29	163	197629	53536	110337971
Alkalosis	19.27	10.29	14	197778	792	110390715
Twin pregnancy	19.26	10.29	15	197777	943	110390564
Pancreatic carcinoma metastatic	19.25	10.29	30	197762	4134	110387373
Lymphocele	19.10	10.29	20	197772	1851	110389656
Photosensitivity reaction	19.09	10.29	11	197781	25578	110365929
Malignant neoplasm progression	18.94	10.29	427	197365	174140	110217367
Blood disorder	18.87	10.29	49	197743	9761	110381746
Foetal heart rate disorder	18.87	10.29	6	197786	48	110391459
Pelvic venous thrombosis	18.86	10.29	24	197768	2740	110388767
Ascites	18.80	10.29	251	197541	92557	110298950
Antithrombin III deficiency	18.69	10.29	8	197784	157	110391350
Superior vena cava syndrome	18.69	10.29	17	197775	1324	110390183
Transfusion-related acute lung injury	18.68	10.29	11	197781	434	110391073
Lymphoedema	18.65	10.29	64	197728	14865	110376642
Diabetic bullosis	18.63	10.29	5	197787	20	110391487
Upper-airway cough syndrome	18.62	10.29	3	197789	15854	110375653
Coordination abnormal	18.60	10.29	11	197781	25217	110366290
Incubator therapy	18.55	10.29	6	197786	51	110391456
Paresis	18.48	10.29	32	197760	4812	110386695
Epidural analgesia	18.33	10.29	8	197784	165	110391342
Amaurosis fugax	18.32	10.29	22	197770	2368	110389139
Atrial thrombosis	18.29	10.29	30	197762	4316	110387191
Mitral valve incompetence	18.25	10.29	112	197680	33217	110358290
Superinfection bacterial	18.24	10.29	22	197770	2379	110389128
Language disorder	18.23	10.29	28	197764	3810	110387697
Transfusion	18.22	10.29	92	197700	25380	110366127
Urinary tract infection	18.20	10.29	735	197057	325547	110065960
Otitis media acute	18.14	10.29	18	197774	1564	110389943
Pericardial effusion	18.13	10.29	169	197623	57048	110334459
Injection site haemorrhage	18.10	10.29	111	197681	32917	110358590
Nausea	18.07	10.29	1935	195857	1233755	109157752
Device toxicity	18.07	10.29	5	197787	23	110391484
Lordosis	18.06	10.29	11	197781	462	110391045
Throat tightness	17.96	10.29	20	197772	33469	110358038
Nightmare	17.95	10.29	26	197766	38837	110352670
Polycystic liver disease	17.94	10.29	8	197784	174	110391333
Prothrombin time shortened	17.88	10.29	27	197765	3619	110387888
Foetal arrhythmia	17.87	10.29	6	197786	58	110391449
Budd-Chiari syndrome	17.78	10.29	7	197785	110	110391397
Escherichia bacteraemia	17.77	10.29	49	197743	10115	110381392
Hepatitis fulminant	17.76	10.29	44	197748	8516	110382991
Vaginal discharge	17.75	10.29	5	197787	17903	110373604
Flushing	17.73	10.29	112	197680	104624	110286883
Haemorrhage coronary artery	17.73	10.29	5	197787	25	110391482
Subileus	17.71	10.29	37	197755	6400	110385107
Adrenal thrombosis	17.66	10.29	4	197788	6	110391501
Serotonin syndrome	17.59	10.29	51	197741	59102	110332405
Basal cell carcinoma	17.47	10.29	34	197758	45236	110346271
Catheter site thrombosis	17.45	10.29	12	197780	622	110390885
Contraindicated product prescribed	17.40	10.29	21	197771	2272	110389235
Intentional self-injury	17.32	10.29	25	197767	37404	110354103
Weight fluctuation	17.27	10.29	9	197783	22136	110369371
Joint injury	17.27	10.29	28	197764	39966	110351541
Breast haematoma	17.18	10.29	8	197784	193	110391314
Respiratory symptom	17.17	10.29	3	197789	14942	110376565
Hydrocephalus	17.14	10.29	49	197743	10326	110381181
Cerebral artery embolism	17.11	10.29	20	197772	2092	110389415
Incorrect route of product administration	17.10	10.29	58	197734	64003	110327504
Poor quality sleep	17.10	10.29	15	197777	28062	110363445
Electrocardiogram repolarisation abnormality	17.09	10.29	21	197771	2314	110389193
Procalcitonin increased	17.07	10.29	28	197764	4028	110387479
Disseminated intravascular coagulation	16.82	10.29	129	197663	41157	110350350
Pleural neoplasm	16.77	10.29	10	197782	404	110391103
Pulmonary alveolar haemorrhage	16.75	10.29	76	197716	20074	110371433
Tinnitus	16.72	10.29	54	197738	60486	110331021
Lipase increased	16.71	10.29	72	197720	18600	110372907
Balance disorder	16.62	10.29	131	197661	116429	110275078
Placental infarction	16.57	10.29	7	197785	133	110391374
Hiatus hernia	16.55	10.29	95	197697	27511	110363996
Pneumothorax	16.53	10.29	114	197678	35171	110356336
Traumatic haematoma	16.49	10.29	21	197771	2400	110389107
Blood albumin decreased	16.48	10.29	95	197697	27557	110363950
Bacteraemia	16.47	10.29	131	197661	42259	110349248
Glycosylated haemoglobin increased	16.45	10.29	11	197781	23608	110367899
Lung disorder	16.38	10.29	225	197567	179822	110211685
Hepatic vein thrombosis	16.34	10.29	9	197783	312	110391195
Musculoskeletal discomfort	16.34	10.29	11	197781	23527	110367980
Enterococcal infection	16.33	10.29	76	197716	20290	110371217
Coagulation test abnormal	16.28	10.29	17	197775	1569	110389938
Toxic encephalopathy	16.27	10.29	62	197730	15152	110376355
Peripheral sensory neuropathy	16.24	10.29	66	197726	16614	110374893
Loss of consciousness	16.22	10.29	463	197329	195843	110195664
Abdominal distension	16.22	10.29	218	197574	174885	110216622
Carcinoid tumour of the small bowel	16.21	10.29	10	197782	430	110391077
Scintillating scotoma	16.19	10.29	8	197784	221	110391286
Pancreatitis acute	16.17	10.29	172	197620	60102	110331405
Post transplant lymphoproliferative disorder	16.15	10.29	4	197788	15609	110375898
Tongue disorder	16.15	10.29	3	197789	14295	110377212
Vascular pseudoaneurysm ruptured	16.08	10.29	11	197781	565	110390942
Protein S deficiency	16.06	10.29	7	197785	144	110391363
Hepatic rupture	16.06	10.29	7	197785	144	110391363
Post procedural haematuria	16.04	10.29	9	197783	324	110391183
Heart rate increased	16.03	10.29	172	197620	143662	110247845
Anti factor X antibody positive	15.98	10.29	3	197789	0	110391507
Non-immune heparin associated thrombocytopenia	15.98	10.29	3	197789	0	110391507
Administration site necrosis	15.98	10.29	3	197789	0	110391507
Pregnancy	15.95	10.29	43	197749	51024	110340483
Immune thrombocytopenia	15.92	10.29	81	197711	22413	110369094
Intentional dose omission	15.90	10.29	8	197784	20072	110371435
Adrenal haematoma	15.88	10.29	7	197785	148	110391359
Haematoma infection	15.87	10.29	17	197775	1615	110389892
Femoral neck fracture	15.81	10.29	54	197738	12513	110378994
Brachiocephalic vein thrombosis	15.81	10.29	9	197783	333	110391174
Parenteral nutrition associated liver disease	15.79	10.29	4	197788	12	110391495
Diffuse alveolar damage	15.78	10.29	27	197765	4020	110387487
Periportal sinus dilatation	15.71	10.29	7	197785	152	110391355
Arrhythmogenic right ventricular dysplasia	15.68	10.29	6	197786	87	110391420
Monoplegia	15.64	10.29	30	197762	4879	110386628
Anaesthesia	15.61	10.29	11	197781	593	110390914
Injection site pain	15.60	10.29	224	197568	177698	110213809
Dehiscence	15.52	10.29	12	197780	746	110390761
Hot flush	15.52	10.29	63	197729	65973	110325534
Radiation fibrosis	15.51	10.29	5	197787	42	110391465
Central nervous system injury	15.46	10.29	7	197785	158	110391349
Coronary artery perforation	15.43	10.29	6	197786	91	110391416
Gastric ulcer	15.43	10.29	123	197669	39704	110351803
Microembolism	15.41	10.29	5	197787	43	110391464
Seasonal allergy	15.41	10.29	8	197784	19714	110371793
Carcinoembryonic antigen	15.37	10.29	6	197786	92	110391415
Abdominal sepsis	15.37	10.29	20	197772	2335	110389172
Eye swelling	15.37	10.29	22	197770	33026	110358481
Gestational diabetes	15.35	10.29	38	197754	7351	110384156
Psychotic symptom	15.35	10.29	26	197766	3841	110387666
Cough	15.34	10.29	672	197120	460969	109930538
Hyperpyrexia	15.21	10.29	40	197752	8029	110383478
Neonatal gastrointestinal disorder	15.21	10.29	5	197787	45	110391462
Rash scarlatiniform	15.20	10.29	9	197783	359	110391148
Anaphylactic reaction	15.14	10.29	131	197661	114169	110277338
Carpal tunnel syndrome	15.12	10.29	11	197781	22599	110368908
Splenic lesion	15.11	10.29	11	197781	624	110390883
Transplant rejection	15.11	10.29	13	197779	24554	110366953
Poor venous access	15.05	10.29	13	197779	24509	110366998
Bone density decreased	14.96	10.29	5	197787	16037	110375470
Carbohydrate antigen 15-3	14.92	10.29	6	197786	100	110391407
Sedation	14.84	10.29	69	197723	69614	110321893
Product administered at inappropriate site	14.84	10.29	31	197761	5362	110386145
Splenic injury	14.75	10.29	8	197784	269	110391238
Uterine enlargement	14.75	10.29	13	197779	972	110390535
Respiratory alkalosis	14.72	10.29	32	197760	5689	110385818
Device occlusion	14.72	10.29	60	197732	15125	110376382
Limb discomfort	14.65	10.29	32	197760	40822	110350685
Lice infestation	14.64	10.29	8	197784	273	110391234
Febrile bone marrow aplasia	14.61	10.29	66	197726	17399	110374108
Intestinal perforation	14.53	10.29	75	197717	20869	110370638
Foetal death	14.46	10.29	62	197730	15983	110375524
Anger	14.42	10.29	8	197784	18999	110372508
Unresponsive to stimuli	14.40	10.29	176	197616	63614	110327893
Soft tissue disorder	14.39	10.29	24	197768	3500	110388007
Stoma site candida	14.35	10.29	4	197788	19	110391488
Clinical trial participant	14.35	10.29	6	197786	111	110391396
Cerebellar haemorrhage	14.34	10.29	23	197769	3248	110388259
International normalised ratio fluctuation	14.33	10.29	26	197766	4054	110387453
Presyncope	14.30	10.29	142	197650	48745	110342762
Gastrointestinal stoma complication	14.24	10.29	23	197769	3266	110388241
Back disorder	14.23	10.29	10	197782	20912	110370595
Chemical burns of eye	14.20	10.29	6	197786	114	110391393
Device safety feature issue	14.15	10.29	8	197784	292	110391215
Diet refusal	14.14	10.29	12	197780	852	110390655
Anorectal malformation	14.08	10.29	5	197787	58	110391449
Drug tolerance	14.08	10.29	6	197786	16579	110374928
Infusion site reaction	14.07	10.29	7	197785	17675	110373832
Morvan syndrome	14.02	10.29	4	197788	21	110391486
Immune effector cell-associated neurotoxicity syndrome	14.01	10.29	58	197734	14724	110376783
Gastrointestinal ulcer haemorrhage	14.00	10.29	16	197776	1634	110389873
Bilirubin conjugated increased	13.99	10.29	33	197759	6191	110385316
Quality of life decreased	13.96	10.29	4	197788	14165	110377342
Restlessness	13.92	10.29	158	197634	56101	110335406
Cerebral haemorrhage foetal	13.91	10.29	3	197789	3	110391504
Hallucination, auditory	13.90	10.29	16	197776	26381	110365126
Hiatus hernia strangulated	13.86	10.29	8	197784	304	110391203
Haemorrhage in pregnancy	13.86	10.29	16	197776	1652	110389855
Personality disorder	13.86	10.29	3	197789	12834	110378673
Large intestinal obstruction	13.85	10.29	25	197767	3883	110387624
Band neutrophil count decreased	13.83	10.29	6	197786	122	110391385
Lymphorrhoea	13.79	10.29	7	197785	205	110391302
Herpes simplex reactivation	13.77	10.29	15	197777	1453	110390054
Renal disorder	13.75	10.29	44	197748	49435	110342072
Respiratory gas exchange disorder	13.74	10.29	12	197780	886	110390621
Panic attack	13.72	10.29	19	197773	28921	110362586
Varicose vein	13.70	10.29	35	197757	6905	110384602
Depressed mood	13.68	10.29	59	197733	60750	110330757
Ventricular hyperkinesia	13.65	10.29	8	197784	313	110391194
Angiokeratoma	13.64	10.29	7	197785	210	110391297
Reversal of sedation	13.63	10.29	5	197787	64	110391443
Neutropenic sepsis	13.62	10.29	98	197694	30648	110360859
Eye pain	13.62	10.29	45	197747	50054	110341453
Cognitive disorder	13.60	10.29	96	197696	87415	110304092
Abdominal compartment syndrome	13.58	10.29	17	197775	1910	110389597
Peripheral artery occlusion	13.53	10.29	21	197771	2884	110388623
Paraparesis	13.45	10.29	27	197765	4539	110386968
Subcapsular hepatic haematoma	13.43	10.29	4	197788	25	110391482
Mean cell volume increased	13.43	10.29	39	197753	8291	110383216
Medication error	13.41	10.29	122	197670	105244	110286263
Dysdiadochokinesis	13.39	10.29	9	197783	449	110391058
Hypercreatininaemia	13.38	10.29	14	197778	1295	110390212
Fear	13.38	10.29	79	197713	23114	110368393
Purpura non-thrombocytopenic	13.31	10.29	7	197785	221	110391286
Deafness bilateral	13.23	10.29	20	197772	2684	110388823
Skin test negative	13.23	10.29	5	197787	70	110391437
Hypoalbuminaemia	13.21	10.29	93	197699	28881	110362626
Hyperaemia	13.20	10.29	24	197768	3749	110387758
Normocytic anaemia	13.17	10.29	33	197759	6434	110385073
Hepatic haemorrhage	13.16	10.29	14	197778	1320	110390187
Blood calcium increased	13.11	10.29	8	197784	18032	110373475
Oesophageal compression	13.05	10.29	4	197788	28	110391479
Iliac vein occlusion	13.05	10.29	4	197788	28	110391479
Pulseless electrical activity	13.04	10.29	62	197730	16695	110374812
Streptococcal bacteraemia	13.04	10.29	27	197765	4642	110386865
Coinfection	13.03	10.29	6	197786	141	110391366
Infarction	13.02	10.29	29	197763	5240	110386267
Allergic sinusitis	13.01	10.29	16	197776	1765	110389742
Dysaesthesia	12.97	10.29	34	197758	6813	110384694
Respiratory acidosis	12.91	10.29	54	197738	13772	110377735
Duodenitis	12.90	10.29	41	197751	9155	110382352
Gingival pain	12.87	10.29	6	197786	15730	110375777
Osteochondrosis	12.84	10.29	19	197773	2502	110389005
Amaurosis	12.80	10.29	15	197777	1574	110389933
Klebsiella sepsis	12.77	10.29	25	197767	4128	110387379
Quadrantanopia	12.73	10.29	7	197785	242	110391265
Nephrolithiasis	12.71	10.29	68	197724	66144	110325363
Abdominal tenderness	12.70	10.29	50	197742	12407	110379100
Spinal cord injury cauda equina	12.69	10.29	6	197786	150	110391357
Middle ear inflammation	12.63	10.29	7	197785	246	110391261
Hemiparesis	12.59	10.29	127	197665	43776	110347731
Ejection fraction decreased	12.58	10.29	120	197672	40760	110350747
Multiple lentigines syndrome	12.55	10.29	7	197785	249	110391258
Urethral stenosis	12.53	10.29	13	197779	1191	110390316
Subcapsular splenic haematoma	12.51	10.29	5	197787	82	110391425
Post thrombotic syndrome	12.48	10.29	10	197782	655	110390852
Protein C deficiency	12.47	10.29	4	197788	33	110391474
Forced expiratory volume decreased	12.47	10.29	4	197788	13172	110378335
Thrombectomy	12.44	10.29	8	197784	370	110391137
Tooth disorder	12.43	10.29	21	197771	29488	110362019
Vitamin K decreased	12.34	10.29	5	197787	85	110391422
Metastatic malignant melanoma	12.33	10.29	22	197770	3387	110388120
Oedema peripheral	12.32	10.29	712	197080	327948	110063559
Antibiotic level above therapeutic	12.30	10.29	12	197780	1021	110390486
Polyserositis	12.29	10.29	12	197780	1022	110390485
Duodenal polyp	12.28	10.29	9	197783	516	110390991
Meningorrhagia	12.27	10.29	8	197784	379	110391128
Abortion spontaneous	12.27	10.29	104	197688	34178	110357329
Mitral perforation	12.27	10.29	4	197788	35	110391472
Liver abscess	12.25	10.29	36	197756	7703	110383804
Abdominal pain lower	12.25	10.29	111	197681	37172	110354335
Hip fracture	12.25	10.29	106	197686	35045	110356462
Acute coronary syndrome	12.24	10.29	77	197715	23035	110368472
Neonatal respiratory depression	12.24	10.29	5	197787	87	110391420
Tooth infection	12.21	10.29	13	197779	22203	110369304
Tissue infiltration	12.20	10.29	12	197780	1031	110390476
Peritoneal carcinoma metastatic	12.18	10.29	5	197787	88	110391419
Intracranial mass	12.17	10.29	18	197774	2370	110389137
Venoocclusive liver disease	12.13	10.29	6	197786	15201	110376306
Infective exacerbation of chronic obstructive airways disease	12.07	10.29	21	197771	3169	110388338
Factor XIII Inhibition	12.07	10.29	4	197788	37	110391470
Pathological fracture	12.03	10.29	48	197744	11984	110379523
Varicella virus test positive	11.99	10.29	8	197784	394	110391113
Infusion site necrosis	11.98	10.29	5	197787	92	110391415
Escherichia sepsis	11.94	10.29	43	197749	10229	110381278
Localised oedema	11.93	10.29	40	197752	9183	110382324
Nephritis allergic	11.86	10.29	12	197780	1067	110390440
Iatrogenic infection	11.83	10.29	5	197787	95	110391412
Cardiopulmonary failure	11.79	10.29	36	197756	7867	110383640
Arterial rupture	11.79	10.29	11	197781	885	110390622
Prosthetic cardiac valve thrombosis	11.78	10.29	5	197787	96	110391411
Nervous system disorder	11.76	10.29	97	197695	31624	110359883
Staphylococcal sepsis	11.76	10.29	62	197730	17392	110374115
Thrombolysis	11.76	10.29	7	197785	282	110391225
Haematocrit abnormal	11.75	10.29	15	197777	1718	110389789
Myocarditis	11.74	10.29	93	197699	29962	110361545
Vascular stent occlusion	11.74	10.29	7	197785	283	110391224
Uterine hypertonus	11.74	10.29	7	197785	283	110391224
Cerebral venous thrombosis	11.73	10.29	21	197771	3241	110388266
Hypersensitivity vasculitis	11.69	10.29	33	197759	6904	110384603
Right ventricular failure	11.66	10.29	83	197709	25871	110365636
COVID-19	11.64	10.29	543	197249	244517	110146990
Clostridial infection	11.64	10.29	31	197761	6271	110385236
Epididymitis	11.63	10.29	18	197774	2466	110389041
Injection site plaque	11.63	10.29	6	197786	182	110391325
Creatinine renal clearance abnormal	11.62	10.29	10	197782	724	110390783
Hypopnoea	11.61	10.29	3	197789	11377	110380130
Body temperature decreased	11.61	10.29	31	197761	36904	110354603
Endocarditis	11.54	10.29	51	197741	13320	110378187
Transfusion-related circulatory overload	11.53	10.29	11	197781	910	110390597
White blood cell count decreased	11.53	10.29	317	197475	229073	110162434
Nervousness	11.53	10.29	31	197761	36820	110354687
Injection site necrosis	11.53	10.29	15	197777	1751	110389756
Hypocapnia	11.52	10.29	11	197781	911	110390596
Hemiplegia	11.51	10.29	75	197717	22707	110368800
Nail toxicity	11.51	10.29	8	197784	422	110391085
Cystitis	11.50	10.29	70	197722	65966	110325541
Sinus tachycardia	11.49	10.29	126	197666	44367	110347140
Agitation	11.48	10.29	274	197518	112777	110278730
Skin cancer	11.45	10.29	9	197783	17775	110373732
Thymus disorder	11.40	10.29	9	197783	577	110390930
Staphylococcus test positive	11.40	10.29	34	197758	7336	110384171
Bacterascites	11.38	10.29	3	197789	11	110391496
Portal vein thrombosis	11.34	10.29	33	197759	7025	110384482
Peripheral embolism	11.33	10.29	16	197776	2019	110389488
Metastases to meninges	11.33	10.29	27	197765	5101	110386406
Appendicitis	11.32	10.29	21	197771	28443	110363064
Mouth haemorrhage	11.31	10.29	51	197741	13437	110378070
Neutrophil count increased	11.30	10.29	103	197689	34549	110356958
Acute abdomen	11.28	10.29	21	197771	3340	110388167
Non-cardiac chest pain	11.27	10.29	42	197750	10156	110381351
Mental status changes	11.21	10.29	195	197597	75927	110315580
Lung infiltration	11.20	10.29	79	197713	24549	110366958
Thrombotic thrombocytopenic purpura	11.18	10.29	33	197759	7078	110384429
Flap necrosis	11.18	10.29	3	197789	12	110391495
Placental necrosis	11.18	10.29	3	197789	12	110391495
Eye infection	11.18	10.29	6	197786	14512	110376995
Drug withdrawal syndrome	11.18	10.29	33	197759	38021	110353486
Bronchial aspiration procedure	11.16	10.29	7	197785	310	110391197
Ventricular flutter	11.16	10.29	5	197787	110	110391397
Platelet disorder	11.15	10.29	22	197770	3653	110387854
Klebsiella bacteraemia	11.15	10.29	26	197766	4843	110386664
Acute encephalitis with refractory, repetitive partial seizures	11.14	10.29	4	197788	48	110391459
Procedural site reaction	11.11	10.29	8	197784	446	110391061
Wrist fracture	11.04	10.29	6	197786	14411	110377096
Laboratory test abnormal	11.03	10.29	41	197751	44038	110347469
Sensorimotor disorder	11.03	10.29	12	197780	1160	110390347
Disease progression	11.02	10.29	538	197254	243496	110148011
Dyspnoea	11.01	10.29	2191	195601	1104681	109286826
Renal vascular thrombosis	11.00	10.29	5	197787	114	110391393
Bullous impetigo	10.99	10.29	3	197789	13	110391494
Therapy partial responder	10.98	10.29	32	197760	37029	110354478
Cardiovascular disorder	10.94	10.29	74	197718	22686	110368821
Eructation	10.93	10.29	52	197740	14005	110377502
Somatosensory evoked potentials abnormal	10.92	10.29	6	197786	207	110391300
Prurigo	10.92	10.29	13	197779	1387	110390120
Burkholderia test positive	10.90	10.29	9	197783	615	110390892
Mitral valve stenosis	10.90	10.29	13	197779	1389	110390118
Multiple-drug resistance	10.90	10.29	5	197787	13230	110378277
Facial pain	10.87	10.29	7	197785	15332	110376175
Pharyngeal haemorrhage	10.86	10.29	13	197779	1394	110390113
Intraocular pressure increased	10.85	10.29	3	197789	10873	110380634
Pulmonary oedema	10.84	10.29	246	197546	100413	110291094
Device related thrombosis	10.84	10.29	21	197771	3441	110388066
Wound secretion	10.83	10.29	32	197760	6869	110384638
Metabolic alkalosis	10.82	10.29	28	197764	5567	110385940
Hepatitis toxic	10.81	10.29	29	197763	5892	110385615
Gastroenteritis viral	10.76	10.29	25	197767	31201	110360306
Septic pulmonary embolism	10.73	10.29	7	197785	332	110391175
Liver function test increased	10.69	10.29	220	197572	88328	110303179
Haemorrhage urinary tract	10.69	10.29	19	197773	2917	110388590
Angle closure glaucoma	10.68	10.29	21	197771	3478	110388029
Pneumonia bacterial	10.67	10.29	82	197710	26179	110365328
Toothache	10.66	10.29	16	197776	23559	110367948
Chronic lymphocytic leukaemia	10.66	10.29	29	197763	5939	110385568
Cardiomyopathy alcoholic	10.65	10.29	4	197788	55	110391452
Parainfluenzae virus infection	10.62	10.29	32	197760	6942	110384565
Splenic embolism	10.59	10.29	6	197786	220	110391287
Urine uric acid decreased	10.57	10.29	5	197787	125	110391382
Subchorionic haematoma	10.57	10.29	5	197787	125	110391382
Eosinophilic granulomatosis with polyangiitis	10.56	10.29	3	197789	10683	110380824
Scratch	10.54	10.29	5	197787	12974	110378533
Anti-platelet antibody positive	10.53	10.29	7	197785	343	110391164
Metabolic acidosis	10.51	10.29	243	197549	99501	110292006
Polyhydramnios	10.47	10.29	15	197777	1918	110389589
Failure to thrive	10.40	10.29	50	197742	13524	110377983
Dementia	10.40	10.29	26	197766	31647	110359860
Consciousness fluctuating	10.40	10.29	16	197776	2180	110389327
Eating disorder	10.40	10.29	25	197767	30833	110360674
Urine output decreased	10.39	10.29	66	197726	19810	110371697
Irritability	10.38	10.29	47	197745	47762	110343745
Gastrointestinal dilation procedure	10.32	10.29	3	197789	17	110391490
Heart sounds abnormal	10.32	10.29	13	197779	1469	110390038
Cerebral ischaemia	10.32	10.29	46	197746	12058	110379449
Low birth weight baby	10.31	10.29	10	197782	845	110390662

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	B01AB05	BLOOD AND BLOOD FORMING ORGANS ANTITHROMBOTIC AGENTS ANTITHROMBOTIC AGENTS Heparin group
MeSH PA	D000925	Anticoagulants
MeSH PA	D006401	Hematologic Agents
FDA CS	M0010191	Heparin, Low-Molecular-Weight
FDA EPC	N0000175586	Low Molecular Weight Heparin
MeSH PA	D002317	Cardiovascular Agents
MeSH PA	D005343	Fibrinolytic Agents
CHEBI has role	CHEBI:22587	antiviral agent
CHEBI has role	CHEBI:33282	antibacterial agent
CHEBI has role	CHEBI:35441	antiinfective agent
CHEBI has role	CHEBI:35554	cardiovascular drug
CHEBI has role	CHEBI:35610	antineoplastic agent
CHEBI has role	CHEBI:38070	anti-arrhythmia drug
CHEBI has role	CHEBI:50249	anticoagulant
CHEBI has role	CHEBI:62868	hepatoprotective agent
CHEBI has role	CHEBI:74518	anti-obesity agent

Related Drugs by ATC class:

B01AB Heparin group 4 drugs

bemiparinheparinnadroparin calciumsulodexide

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Unstable angina	indication	4557003
Myocardial infarction	indication	22298006	DOID:5844
Pulmonary embolism	indication	59282003	DOID:9477
Deep venous thrombosis	indication	128053003
Prevention of clot formation during haemodialysis	indication
Prevention of venous thromboembolism	indication

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Antithrombin-III	Secreted	P01008	ANT3_HUMAN	ACTIVATOR				WOMBAT-PK	CHEMBL

External reference:

ID	Source
D03674	KEGG_DRUG
4020831	VANDF
CHEBI:749476	CHEBI
CHEMBL1201476	ChEMBL_ID
CHEMBL1201685	ChEMBL_ID
C000711671	MESH_SUPPLEMENTAL_RECORD_UI
DB01225	DRUGBANK_ID
221095	RXNORM
1304	MMSL
175440	MMSL
4659	MMSL
d03041	MMSL
004210	NDDF
006123	NDDF
108983001	SNOMEDCT_US
108984007	SNOMEDCT_US
372562003	SNOMEDCT_US
C0724579	UMLSCUI
5452	INN_ID
9005-49-6	SECONDARY_CAS_RN
6811	IUPHAR_LIGAND_ID
8NZ41MIK1O	UNII
D017984	MESH_DESCRIPTOR_UI

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Lovenox	HUMAN PRESCRIPTION DRUG LABEL	1	0075-0620	INJECTION	40 mg	SUBCUTANEOUS	NDA	30 sections
Lovenox	HUMAN PRESCRIPTION DRUG LABEL	1	0075-0621	INJECTION	60 mg	SUBCUTANEOUS	NDA	30 sections
Lovenox	HUMAN PRESCRIPTION DRUG LABEL	1	0075-0622	INJECTION	80 mg	SUBCUTANEOUS	NDA	30 sections
Lovenox	HUMAN PRESCRIPTION DRUG LABEL	1	0075-0623	INJECTION	100 mg	SUBCUTANEOUS	NDA	30 sections
Lovenox	HUMAN PRESCRIPTION DRUG LABEL	1	0075-0624	INJECTION	30 mg	SUBCUTANEOUS	NDA	30 sections
Lovenox	HUMAN PRESCRIPTION DRUG LABEL	1	0075-0626	INJECTION	300 mg	SUBCUTANEOUS	NDA	30 sections
Lovenox	HUMAN PRESCRIPTION DRUG LABEL	1	0075-2912	INJECTION	120 mg	SUBCUTANEOUS	NDA	30 sections
Lovenox	HUMAN PRESCRIPTION DRUG LABEL	1	0075-2915	INJECTION	150 mg	SUBCUTANEOUS	NDA	30 sections
Lovenox	HUMAN PRESCRIPTION DRUG LABEL	1	0075-8013	INJECTION	30 mg	SUBCUTANEOUS	NDA	30 sections
Lovenox	HUMAN PRESCRIPTION DRUG LABEL	1	0075-8014	INJECTION	40 mg	SUBCUTANEOUS	NDA	30 sections
Lovenox	HUMAN PRESCRIPTION DRUG LABEL	1	0075-8016	INJECTION	60 mg	SUBCUTANEOUS	NDA	30 sections
Lovenox	HUMAN PRESCRIPTION DRUG LABEL	1	0075-8018	INJECTION	80 mg	SUBCUTANEOUS	NDA	30 sections
Lovenox	HUMAN PRESCRIPTION DRUG LABEL	1	0075-8020	INJECTION	100 mg	SUBCUTANEOUS	NDA	30 sections
Lovenox	HUMAN PRESCRIPTION DRUG LABEL	1	0075-8022	INJECTION	120 mg	SUBCUTANEOUS	NDA	30 sections
Lovenox	HUMAN PRESCRIPTION DRUG LABEL	1	0075-8025	INJECTION	150 mg	SUBCUTANEOUS	NDA	30 sections
Lovenox	HUMAN PRESCRIPTION DRUG LABEL	1	0075-8030	INJECTION	300 mg	SUBCUTANEOUS	NDA	30 sections
Enoxaparin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0548-5601	INJECTION	100 mg	SUBCUTANEOUS	ANDA	29 sections
Enoxaparin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0548-5602	INJECTION	100 mg	SUBCUTANEOUS	ANDA	29 sections
Enoxaparin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0548-5603	INJECTION	100 mg	SUBCUTANEOUS	ANDA	29 sections
Enoxaparin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0548-5604	INJECTION	100 mg	SUBCUTANEOUS	ANDA	29 sections
Enoxaparin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0548-5605	INJECTION	100 mg	SUBCUTANEOUS	ANDA	29 sections
Enoxaparin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0548-5606	INJECTION	150 mg	SUBCUTANEOUS	ANDA	29 sections
Enoxaparin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0548-5607	INJECTION	150 mg	SUBCUTANEOUS	ANDA	29 sections
Enoxaparin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0548-5608	INJECTION	300 mg	SUBCUTANEOUS	ANDA	29 sections
Enoxaparin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0781-3238	INJECTION	100 mg	SUBCUTANEOUS	ANDA	28 sections
Enoxaparin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0781-3246	INJECTION	100 mg	SUBCUTANEOUS	ANDA	28 sections
Enoxaparin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0781-3256	INJECTION	100 mg	SUBCUTANEOUS	ANDA	28 sections
Enoxaparin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0781-3262	INJECTION	100 mg	SUBCUTANEOUS	ANDA	28 sections
Enoxaparin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0781-3268	INJECTION	100 mg	SUBCUTANEOUS	ANDA	28 sections
Enoxaparin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0781-3298	INJECTION	150 mg	SUBCUTANEOUS	ANDA	28 sections