guaiazulen 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
3272 489-84-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • guaiazulen
  • guaiazulene
  • azulon
  • azunol
  • eucazulen
  • kessazulen
  • purazulen
  • silazulon
  • uroazulen
  • vetivazulen
  • Molecular weight: 198.31
  • Formula: C15H18
  • CLOGP: 5.74
  • LIPINSKI: 1
  • HAC: 0
  • HDO: 0
  • TPSA:
  • ALOGS: -3.15
  • ROTB: 1

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AKT2,AKT3,ALK,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GSK3B,IKBKB,ITK,JAK2,MAP2K6,MAP3K1,MAP3K21,MAP3K7,MAPK10,MAPK7,MAPK9,MAPKAPK2,MET,MTOR,NTRK2,PDK4,PDPK1,PIK3CB,PIK3CG,PIM2,PRKCD,PRKDC,SIK2,SIK3,STK33,TEK,TGFBR1,TTK 48
kinase-selectivity-class AXL,BRAF,EIF2AK3,PDK4 4
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC S01XA01 SENSORY ORGANS
OPHTHALMOLOGICALS
OTHER OPHTHALMOLOGICALS
Other ophthalmologicals
CHEBI has role CHEBI:66981 ophthalmology drug

Related Drugs by ATC class:

S01XA Other ophthalmologicals 24 drugs
acetylcysteinealteplasealumascorbic acidavacincaptad pegolcenegerminciclosporindexpanthenoldiquafosolethylmorphineheparininosine show all 24 →

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C0061932 UMLSCUI
CHEMBL1408759 ChEMBL_ID
3515 PUBCHEM_CID
DB13329 DRUGBANK_ID
C004451 MESH_SUPPLEMENTAL_RECORD_UI
26290 RXNORM
005423 NDDF
CHEBI:5550 CHEBI
2OZ1K9JKQC UNII
2OZ1K9JKQC INXIGHT DRUGS

Pharmaceutical products:

None