magnesium oxide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
4293 1309-48-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • magnesium oxide
Magnesium oxide (MgO). An inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses.
  • Molecular weight: 40.30
  • Formula: MgO
  • CLOGP: -1.32
  • LIPINSKI: None
  • HAC: 1
  • HDO: 0
  • TPSA: 17.07
  • ALOGS:
  • ROTB: 0

Drug dosage:

DoseUnitRoute
7 g O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

DateAgencyCompanyOrphan
June 22, 1982 FDA BAXTER HLTHCARE

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Pemphigus 1425.52 9.72 6472 846276 320392 89455307
Systemic lupus erythematosus 1414.57 9.72 6941 845807 354955 89420744
Glossodynia 1208.33 9.72 6103 846645 315676 89460023
Hand deformity 993.39 9.72 5448 847300 290914 89484785
Arthropathy 981.67 9.72 6349 846399 359893 89415806
Toxicity to various agents 957.15 9.72 782 851966 287064 89488635
Completed suicide 946.78 9.72 123 852625 144935 89630764
Abdominal discomfort 871.99 9.72 7557 845191 469771 89305928
Alopecia 864.70 9.72 7761 844987 487310 89288389
Wound 800.79 9.72 5235 847513 297745 89477954
Synovitis 713.17 9.72 5427 847321 324325 89451374
Maternal exposure during pregnancy 681.79 9.72 5748 847000 354315 89421384
Anti-cyclic citrullinated peptide antibody positive 660.01 9.72 4143 848605 232290 89543409
Pericarditis 652.72 9.72 4566 848182 265585 89510114
Swelling 643.01 9.72 6393 846355 412665 89363034
Contraindicated product administered 584.44 9.72 5070 847678 315069 89460630
Discomfort 581.71 9.72 4495 848253 269840 89505859
Infusion related reaction 532.72 9.72 6130 846618 410650 89365049
Duodenal ulcer perforation 530.70 9.72 3734 849014 217554 89558145
Joint swelling 511.00 9.72 7092 845656 496208 89279491
Intentional overdose 506.12 9.72 129 852619 93705 89681994
Drug interaction 494.43 9.72 1174 851574 275279 89500420
Death 487.39 9.72 2423 850325 454128 89321571
Helicobacter infection 481.85 9.72 3719 849029 223131 89552568
Drug abuse 436.90 9.72 117 852631 82230 89693469
Rheumatoid factor positive 411.72 9.72 2897 849851 168753 89606946
Rheumatoid arthritis 401.61 9.72 5192 847556 357422 89418277
Pain 363.52 9.72 12087 840661 984254 88791445
Suicide attempt 362.45 9.72 128 852620 75271 89700428
Psoriatic arthropathy 345.42 9.72 3475 849273 224860 89550839
Hepatic enzyme increased 326.34 9.72 4984 847764 355752 89419947
Therapeutic product effect decreased 289.06 9.72 3931 848817 273640 89502059
Overdose 283.15 9.72 668 852080 157041 89618658
Musculoskeletal stiffness 273.87 9.72 4112 848636 292420 89483279
Arthralgia 270.21 9.72 9393 843355 769129 89006570
Impaired healing 264.32 9.72 3366 849382 230833 89544866
Product use issue 258.97 9.72 4453 848295 325466 89450233
Disease progression 244.06 9.72 712 852036 155903 89619796
Cardiac arrest 241.88 9.72 383 852365 104552 89671147
Lactic acidosis 233.57 9.72 91 852657 50372 89725327
Folliculitis 233.51 9.72 2944 849804 201409 89574290
Neutropenia 232.53 9.72 1206 851542 223698 89552001
Rheumatic fever 232.22 9.72 2332 850416 150789 89624910
Hyperhidrosis 225.49 9.72 602 852146 135703 89639996
Acute kidney injury 218.41 9.72 1944 850804 318443 89457256
Blister 217.77 9.72 3490 849258 251508 89524191
Constipation 210.69 9.72 1658 851090 278737 89496962
Sedation 208.33 9.72 96 852652 48075 89727624
Drug ineffective for unapproved indication 204.41 9.72 195 852553 66449 89709250
Hypotension 201.04 9.72 2023 850725 323374 89452325
Electrocardiogram QT prolonged 200.88 9.72 231 852517 72225 89703474
Febrile neutropenia 196.48 9.72 794 851954 157555 89618144
Sleep disorder due to general medical condition, insomnia type 191.75 9.72 1953 850795 126741 89648958
Muscle injury 191.67 9.72 2521 850227 174133 89601566
Swollen joint count increased 188.50 9.72 1734 851014 109472 89666227
Drug intolerance 183.82 9.72 5512 847236 442079 89333620
Irritable bowel syndrome 179.23 9.72 2845 849903 204603 89571096
Type 2 diabetes mellitus 176.60 9.72 2790 849958 200454 89575245
Somnolence 175.94 9.72 1197 851551 207887 89567812
Exposure during pregnancy 173.79 9.72 3181 849567 235229 89540470
Hip arthroplasty 172.61 9.72 1269 851479 74939 89700760
Knee arthroplasty 171.54 9.72 1355 851393 81827 89693872
Fibromyalgia 170.05 9.72 2807 849941 203462 89572237
Nausea 167.95 9.72 8641 844107 1101675 88674024
Depressed level of consciousness 167.39 9.72 266 852482 72518 89703181
Nasopharyngitis 166.46 9.72 5011 847737 402093 89373606
Agitation 165.18 9.72 234 852514 66864 89708835
Drug reaction with eosinophilia and systemic symptoms 164.57 9.72 99 852649 42659 89733040
Off label use 160.68 9.72 8610 844138 1093642 88682057
C-reactive protein abnormal 158.60 9.72 1866 850882 125563 89650136
Sopor 158.09 9.72 22 852726 24622 89751077
Hypersensitivity 158.00 9.72 5489 847259 449188 89326511
Coma 157.26 9.72 276 852472 72356 89703343
Serotonin syndrome 156.99 9.72 80 852668 37807 89737892
Treatment failure 155.38 9.72 3851 848897 300077 89475622
Angioedema 155.05 9.72 231 852517 64645 89711054
Cognitive disorder 154.62 9.72 259 852489 69148 89706551
Stomatitis 154.23 9.72 3526 849222 271172 89504527
Bradycardia 153.78 9.72 351 852397 83496 89692203
Tremor 153.44 9.72 830 851918 152343 89623356
Blood cholesterol increased 148.99 9.72 2768 849980 205244 89570455
Red blood cell sedimentation rate abnormal 148.01 9.72 533 852215 23671 89752028
Hyponatraemia 146.59 9.72 701 852047 132837 89642862
Myelosuppression 146.24 9.72 173 852575 53418 89722281
Drug resistance 145.80 9.72 52 852696 30397 89745302
Lower respiratory tract infection 145.27 9.72 3232 849516 247427 89528272
Ill-defined disorder 140.01 9.72 2482 850266 182409 89593290
Intentional self-injury 138.92 9.72 51 852697 29283 89746416
Malignant neoplasm progression 138.85 9.72 526 852222 106344 89669355
Chest discomfort 136.80 9.72 753 851995 137612 89638087
No adverse event 134.29 9.72 273 852475 67709 89707990
Sickle cell anaemia with crisis 127.78 9.72 239 852509 7058 89768641
Myalgia 125.28 9.72 1049 851699 174076 89601623
Intentional product misuse 124.36 9.72 429 852319 89175 89686524
Renal failure 124.09 9.72 723 852025 130284 89645415
Syncope 121.50 9.72 740 852008 131923 89643776
Contusion 120.38 9.72 3156 849592 248060 89527639
Device expulsion 120.35 9.72 124 852624 40762 89734937
Liver injury 120.13 9.72 2264 850484 168303 89607396
Diarrhoea 116.71 9.72 7447 845301 931743 88843956
Thrombocytopenia 114.23 9.72 1334 851414 207391 89568308
Metabolic acidosis 113.05 9.72 220 852528 55456 89720243
Vision blurred 110.25 9.72 598 852150 109695 89666004
Osteoarthritis 107.81 9.72 2506 850242 193224 89582475
Dyspnoea 106.19 9.72 7004 845744 873951 88901748
Sedation complication 104.39 9.72 17 852731 16927 89758772
Neoplasm progression 103.79 9.72 161 852587 44325 89731374
Hepatocellular injury 103.35 9.72 73 852675 28885 89746814
Intentional product use issue 102.79 9.72 2721 850027 214171 89561528
Balance disorder 101.71 9.72 518 852230 96562 89679137
Pregnancy 100.85 9.72 959 851789 61088 89714611
Neuropathy peripheral 100.43 9.72 815 851933 136155 89639544
Respiratory arrest 100.37 9.72 99 852649 33212 89742487
Hypoglycaemia 97.88 9.72 333 852415 69515 89706184
Accidental exposure to product 97.25 9.72 155 852593 42211 89733488
Food allergy 96.64 9.72 60 852688 25418 89750281
Tachycardia 96.54 9.72 982 851766 156691 89619008
COVID-19 95.14 9.72 1072 851676 167771 89607928
Anaphylactic reaction 93.98 9.72 463 852285 87061 89688638
Rhabdomyolysis 93.63 9.72 215 852533 51041 89724658
Anxiety 93.05 9.72 2211 850537 307561 89468138
Skin exfoliation 92.99 9.72 327 852421 67586 89708113
Drug withdrawal syndrome 92.89 9.72 80 852668 28643 89747056
Multiple organ dysfunction syndrome 92.26 9.72 331 852417 68005 89707694
Product dose omission issue 91.51 9.72 2068 850680 289619 89486080
Rash erythematous 91.49 9.72 310 852438 64794 89710905
Temperature regulation disorder 91.24 9.72 14 852734 14565 89761134
Seizure 91.22 9.72 956 851792 151673 89624026
Palpitations 91.13 9.72 834 851914 135894 89639805
Creatinine renal clearance decreased 90.96 9.72 32 852716 18867 89756832
Cardio-respiratory arrest 90.55 9.72 298 852450 62842 89712857
Injury 89.28 9.72 2461 850287 194888 89580811
Suicidal ideation 89.27 9.72 374 852374 73481 89702218
Product use in unapproved indication 88.69 9.72 2446 850302 333790 89441909
Drug dependence 88.54 9.72 87 852661 29240 89746459
Multiple sclerosis relapse 87.99 9.72 229 852519 52076 89723623
Orthostatic hypotension 87.80 9.72 162 852586 41665 89734034
Dry skin 87.76 9.72 478 852270 87595 89688104
Live birth 87.43 9.72 1133 851615 77974 89697725
Disturbance in attention 87.35 9.72 196 852552 46913 89728786
Pulmonary fibrosis 87.06 9.72 1459 851289 106044 89669655
Inflammation 85.90 9.72 2245 850503 176347 89599352
Facet joint syndrome 84.77 9.72 1349 851399 97040 89678659
Grip strength decreased 83.45 9.72 1279 851469 91297 89684402
Dysarthria 83.15 9.72 250 852498 54232 89721467
Cholestasis 83.14 9.72 133 852615 36166 89739533
Joint range of motion decreased 82.66 9.72 1762 850986 133881 89641818
Cardiac failure 82.36 9.72 647 852101 108849 89666850
C-reactive protein increased 80.08 9.72 2255 850493 179134 89596565
Blood pressure diastolic abnormal 79.25 9.72 384 852364 19497 89756202
Feeling abnormal 79.14 9.72 1102 851646 166133 89609566
Respiratory failure 79.05 9.72 722 852026 117696 89658003
Asthenia 77.96 9.72 4166 848582 529585 89246114
Personality disorder 77.76 9.72 12 852736 12432 89763267
Blood pressure systolic abnormal 77.49 9.72 376 852372 19102 89756597
Weight increased 77.41 9.72 4736 848012 413191 89362508
Flushing 77.20 9.72 501 852247 87990 89687709
General physical health deterioration 76.73 9.72 4081 848667 351034 89424665
Myocardial infarction 76.11 9.72 634 852114 105338 89670361
Ejection fraction decreased 75.72 9.72 81 852667 26172 89749527
Fatigue 75.72 9.72 12157 840591 1141866 88633833
Wrong technique in product usage process 74.90 9.72 382 852366 71189 89704510
Mydriasis 74.72 9.72 24 852724 14988 89760711
Rash 74.68 9.72 8568 844180 787532 88988167
Peripheral swelling 74.59 9.72 4671 848077 408435 89367264
Metastases to bone 74.34 9.72 78 852670 25427 89750272
Anaphylactic shock 74.17 9.72 114 852634 31503 89744196
Hepatic failure 73.08 9.72 166 852582 39562 89736137
Disability assessment scale score increased 72.93 9.72 132 852616 3799 89771900
Neurotoxicity 72.89 9.72 57 852691 21410 89754289
Sinusitis 72.57 9.72 3935 848813 339153 89436546
Dysphagia 72.18 9.72 691 852057 111587 89664112
Neurologic neglect syndrome 70.28 9.72 3 852745 8844 89766855
Deep vein thrombosis postoperative 69.58 9.72 993 851755 69816 89705883
Cough 68.39 9.72 2807 849941 366155 89409544
Condition aggravated 68.02 9.72 6496 846252 589049 89186650
Poisoning 67.88 9.72 29 852719 15188 89760511
Back pain 67.39 9.72 2374 850374 314801 89460898
Device difficult to use 66.85 9.72 41 852707 17484 89758215
Blood glucose increased 66.52 9.72 574 852174 94672 89681027
Hyperglycaemia 66.10 9.72 251 852497 50719 89724980
Vomiting 65.72 9.72 6456 846292 781837 88993862
Red blood cell sedimentation rate increased 65.43 9.72 1117 851631 81478 89694221
Hepatotoxicity 65.29 9.72 217 852531 45625 89730074
Arthritis 65.16 9.72 2048 850700 165267 89610432
Suspected suicide 65.15 9.72 7 852741 9561 89766138
Joint effusion 64.26 9.72 360 852388 19350 89756349
Leukopenia 64.23 9.72 621 852127 100089 89675610
Dermatitis atopic 63.79 9.72 76 852672 23396 89752303
Disease recurrence 63.22 9.72 165 852583 37488 89738211
Emotional distress 62.83 9.72 159 852589 36503 89739196
Lip dry 62.66 9.72 1315 851433 99640 89676059
Hypomania 61.90 9.72 6 852742 8891 89766808
Mobility decreased 61.67 9.72 2918 849830 247816 89527883
Depressed mood 61.52 9.72 253 852495 49969 89725730
Therapy partial responder 61.39 9.72 70 852678 21973 89753726
Encephalopathy 61.35 9.72 227 852521 46217 89729482
Diabetic ketoacidosis 61.18 9.72 84 852664 24323 89751376
Swollen tongue 61.11 9.72 224 852524 45732 89729967
Blood calcium decreased 60.63 9.72 120 852628 30062 89745637
Hemiparesis 60.13 9.72 131 852617 31688 89744011
Erythema 60.06 9.72 1669 851079 227577 89548122
Cytokine release syndrome 59.91 9.72 107 852641 27866 89747833
Headache 59.67 9.72 7158 845590 855588 88920111
Hypermagnesaemia 59.65 9.72 66 852682 1183 89774516
Skin haemorrhage 59.43 9.72 68 852680 21312 89754387
Acute hepatic failure 59.26 9.72 75 852673 22486 89753213
Exposure to toxic agent 59.24 9.72 4 852744 7963 89767736
Polyneuropathy 58.82 9.72 57 852691 19284 89756415
Psychotic disorder 58.67 9.72 129 852619 31101 89744598
Fluid retention 58.39 9.72 538 852210 87553 89688146
Unresponsive to stimuli 58.12 9.72 175 852573 37946 89737753
Cerebrovascular accident 58.09 9.72 815 851933 122718 89652981
Aphasia 58.03 9.72 207 852541 42605 89733094
Withdrawal syndrome 58.00 9.72 76 852672 22448 89753251
Blood pressure systolic increased 57.64 9.72 819 851929 57526 89718173
Infection 57.59 9.72 4051 848697 358043 89417656
Hallucination 57.24 9.72 374 852374 65585 89710114
Ventricular tachycardia 57.09 9.72 90 852658 24618 89751081
Muscle spasticity 56.88 9.72 158 852590 35164 89740535
Abortion spontaneous 56.73 9.72 767 851981 53289 89722410
Disorientation 56.72 9.72 218 852530 43896 89731803
Shock 56.46 9.72 116 852632 28662 89747037
Dizziness 56.14 9.72 4777 847971 584507 89191192
Bone pain 56.08 9.72 347 852401 61636 89714063
Obesity 55.35 9.72 1342 851406 104165 89671534
Vertigo 55.09 9.72 407 852341 69404 89706295
Drug hypersensitivity 54.95 9.72 3690 849058 459919 89315780
Juvenile idiopathic arthritis 54.94 9.72 118 852630 3859 89771840
Torsade de pointes 54.54 9.72 38 852710 15144 89760555
Foot deformity 54.47 9.72 826 851922 58825 89716874
Extrapyramidal disorder 54.46 9.72 44 852704 16259 89759440
Autoimmune disorder 54.45 9.72 1020 851728 75724 89699975
Restlessness 54.44 9.72 164 852584 35556 89740143
Carotid artery thrombosis 54.09 9.72 10 852738 9082 89766617
Schizophrenia 54.01 9.72 37 852711 14877 89760822
Posterior reversible encephalopathy syndrome 53.90 9.72 79 852669 22260 89753439
Joint destruction 53.22 9.72 257 852491 13030 89762669
Nasal polyps 53.09 9.72 18 852730 10862 89764837
Drug level increased 52.71 9.72 114 852634 27648 89748051
Hemiplegia 52.27 9.72 45 852703 16115 89759584
Coordination abnormal 52.04 9.72 75 852673 21281 89754418
Thrombotic microangiopathy 51.95 9.72 43 852705 15700 89759999
Eye pruritus 51.22 9.72 124 852624 28903 89746796
Respiratory depression 50.83 9.72 43 852705 15532 89760167
Palmar-plantar erythrodysaesthesia syndrome 50.81 9.72 118 852630 27905 89747794
Basal cell carcinoma 50.79 9.72 509 852239 32880 89742819
Adjustment disorder 50.57 9.72 14 852734 9628 89766071
Polyarthritis 50.11 9.72 320 852428 18030 89757669
Blood pressure fluctuation 49.90 9.72 731 852017 51682 89724017
Anaemia 49.70 9.72 2763 849985 350039 89425660
Haematotoxicity 49.69 9.72 28 852720 12507 89763192
Wound infection 49.54 9.72 1332 851416 105070 89670629
Renal impairment 49.39 9.72 696 852052 104725 89670974
Metastases to liver 49.32 9.72 125 852623 28682 89747017
Bronchospasm 49.22 9.72 74 852674 20635 89755064
Respiratory distress 49.08 9.72 194 852554 38752 89736947
Pain in jaw 48.59 9.72 259 852489 47726 89727973
Hyperkalaemia 48.31 9.72 385 852363 64579 89711120
Cytomegalovirus infection 48.25 9.72 112 852636 26490 89749209
Angina pectoris 48.13 9.72 197 852551 38963 89736736
Eating disorder 47.92 9.72 122 852626 27951 89747748
Hypercholesterolaemia 47.82 9.72 1266 851482 99626 89676073
Post transplant lymphoproliferative disorder 47.53 9.72 5 852743 6944 89768755
Speech disorder 47.30 9.72 244 852504 45341 89730358
Joint laxity 47.18 9.72 87 852661 2541 89773158
Hypoxia 46.77 9.72 445 852303 71954 89703745
Eczema 46.27 9.72 299 852449 52571 89723128
Muscle twitching 46.27 9.72 99 852649 24103 89751596
Illness 45.92 9.72 521 852227 81448 89694251
Acute generalised exanthematous pustulosis 45.75 9.72 37 852711 13666 89762033
Sciatica 45.73 9.72 1264 851484 100118 89675581
Foetal exposure during pregnancy 45.60 9.72 611 852137 42364 89733335
Status epilepticus 45.29 9.72 67 852681 18807 89756892
Dystonia 45.13 9.72 55 852693 16764 89758935
Rebound effect 44.97 9.72 16 852732 9368 89766331
Arterial occlusive disease 44.91 9.72 31 852717 12415 89763284
Pulmonary embolism 44.89 9.72 914 851834 129906 89645793
Prescribed underdose 44.88 9.72 972 851776 74047 89701652
Gestational diabetes 44.81 9.72 208 852540 10374 89765325
Adjustment disorder with depressed mood 44.75 9.72 767 851981 55986 89719713
Hepatic cytolysis 44.26 9.72 146 852602 30770 89744929
Akathisia 44.13 9.72 25 852723 11134 89764565
Hypothermia 43.87 9.72 49 852699 15526 89760173
Exposure via skin contact 43.76 9.72 23 852725 10682 89765017
Obstructive airways disorder 43.71 9.72 113 852635 25756 89749943
Premature labour 43.40 9.72 244 852504 13132 89762567
Adverse event 43.04 9.72 1427 851321 115991 89659708
Motor dysfunction 42.60 9.72 72 852676 19158 89756541
Dislocation of vertebra 42.56 9.72 752 851996 55216 89720483
Lethargy 42.11 9.72 385 852363 62754 89712945
Chronic kidney disease 41.84 9.72 288 852460 49903 89725796
Pancreatitis acute 41.74 9.72 158 852590 31957 89743742
Breast cancer stage III 41.28 9.72 1064 851684 83383 89692316
Chills 41.26 9.72 936 851812 131045 89644654
Multiple drug therapy 41.08 9.72 8 852740 7001 89768698
Peripheral venous disease 40.92 9.72 1057 851691 82864 89692835
Bone erosion 40.89 9.72 714 852034 52307 89723392
Caesarean section 40.72 9.72 307 852441 18270 89757429
Sensory loss 40.67 9.72 67 852681 18008 89757691
Cardiac failure congestive 40.62 9.72 668 852080 98026 89677673
Affect lability 40.60 9.72 67 852681 17996 89757703
Diabetes mellitus inadequate control 40.44 9.72 71 852677 18613 89757086
Arrhythmia 40.40 9.72 233 852515 42099 89733600
Mucosal inflammation 40.36 9.72 347 852401 57278 89718421
Forced expiratory volume decreased 40.19 9.72 4 852744 5804 89769895
Second primary malignancy 39.97 9.72 24 852724 10354 89765345
Paradoxical drug reaction 39.83 9.72 4 852744 5762 89769937
Irritability 39.82 9.72 186 852562 35476 89740223
Dysgeusia 39.78 9.72 310 852438 52250 89723449
Coagulopathy 39.14 9.72 102 852646 23187 89752512
Haemorrhage 38.83 9.72 441 852307 68928 89706771
Myoclonus 38.68 9.72 76 852672 19092 89756607
Eosinophilia 38.65 9.72 138 852610 28395 89747304
Musculoskeletal pain 37.93 9.72 1973 850775 169278 89606421
Gait inability 37.83 9.72 1713 851035 144743 89630956
Oedema 37.80 9.72 2274 850474 198021 89577678
Swelling face 37.78 9.72 538 852210 80814 89694885
Loss of personal independence in daily activities 37.60 9.72 1603 851145 134502 89641197
Cardiogenic shock 37.53 9.72 112 852636 24356 89751343
Road traffic accident 37.42 9.72 1300 851448 106326 89669373
Influenza like illness 37.12 9.72 534 852214 80077 89695622
Dehydration 37.12 9.72 1474 851274 192973 89582726
Lip swelling 37.12 9.72 212 852536 38398 89737301
Blood pressure diastolic decreased 37.05 9.72 401 852347 26425 89749274
Brain oedema 36.78 9.72 67 852681 17318 89758381
Substance abuse 36.70 9.72 4 852744 5402 89770297
Tinnitus 36.59 9.72 246 852502 42856 89732843
Mental disorder 36.42 9.72 168 852580 32150 89743549
Loss of consciousness 36.19 9.72 1023 851725 139215 89636484
Rheumatoid nodule 35.96 9.72 318 852430 19848 89755851
Bursitis 35.35 9.72 1546 851202 130108 89645591
Sepsis 35.21 9.72 1359 851389 178455 89597244
Device use error 35.14 9.72 12 852736 7209 89768490
Complication of device insertion 35.07 9.72 28 852720 10408 89765291
Drug dose omission by device 34.95 9.72 27 852721 10204 89765495
Asthma-chronic obstructive pulmonary disease overlap syndrome 34.90 9.72 3 852745 4896 89770803
Face oedema 34.86 9.72 108 852640 23210 89752489
Aggression 34.79 9.72 131 852617 26537 89749162
Bradyphrenia 34.77 9.72 14 852734 7598 89768101
Small for dates baby 34.74 9.72 115 852633 4892 89770807
Skin burning sensation 34.43 9.72 84 852664 19527 89756172
Abnormal behaviour 34.41 9.72 104 852644 22524 89753175
Multiple-drug resistance 34.40 9.72 15 852733 7761 89767938
Metastases to central nervous system 34.17 9.72 71 852677 17471 89758228
Drug tolerance decreased 34.17 9.72 457 852291 31673 89744026
Haemophagocytic lymphohistiocytosis 34.14 9.72 58 852690 15401 89760298
Cardiotoxicity 34.13 9.72 34 852714 11355 89764344
Gastrointestinal disorder 33.99 9.72 2831 849917 253856 89521843
Atrial fibrillation 33.89 9.72 977 851771 132634 89643065
Neck deformity 33.82 9.72 68 852680 2121 89773578
Tachypnoea 33.81 9.72 96 852652 21213 89754486
Gangrene 33.62 9.72 43 852705 12833 89762866
Gamma-glutamyltransferase increased 33.54 9.72 214 852534 37738 89737961
Sinus tachycardia 33.46 9.72 146 852602 28367 89747332
Panic attack 33.44 9.72 131 852617 26234 89749465
Joint stiffness 32.97 9.72 965 851783 77077 89698622
Nightmare 32.92 9.72 100 852648 21625 89754074
Cytopenia 32.84 9.72 72 852676 17377 89758322
Venoocclusive liver disease 32.77 9.72 8 852740 5985 89769714
Liver disorder 32.76 9.72 1425 851323 119844 89655855
Parkinsonism 32.71 9.72 51 852697 14014 89761685
Mental status changes 32.66 9.72 266 852482 44413 89731286
Macular degeneration 32.59 9.72 216 852532 37754 89737945
Acute graft versus host disease 32.56 9.72 6 852742 5462 89770237
Miosis 32.43 9.72 25 852723 9459 89766240
Nodule 32.39 9.72 389 852359 26297 89749402
C-reactive protein 32.06 9.72 443 852305 30924 89744775
Accidental overdose 31.84 9.72 147 852601 28126 89747573
Osteoporosis 31.83 9.72 1159 851589 95372 89680327
Dyskinesia 31.78 9.72 207 852541 36327 89739372
Febrile bone marrow aplasia 31.64 9.72 27 852721 9711 89765988
Crying 31.52 9.72 129 852619 25516 89750183
Eye irritation 31.37 9.72 189 852559 33789 89741910
Muscle rigidity 31.31 9.72 54 852694 14255 89761444
Device dislocation 31.28 9.72 171 852577 31311 89744388
Tardive dyskinesia 31.21 9.72 34 852714 10896 89764803
Haematoma 31.12 9.72 227 852521 38821 89736878
Pathogen resistance 30.93 9.72 19 852729 8096 89767603
Ischaemic stroke 30.83 9.72 106 852642 22060 89753639
Colitis 30.59 9.72 468 852280 69474 89706225
Aspergillus infection 30.54 9.72 34 852714 10789 89764910
Product preparation error 30.33 9.72 31 852717 10230 89765469
Immune reconstitution inflammatory syndrome 30.33 9.72 14 852734 7005 89768694
Rhinitis allergic 30.17 9.72 71 852677 16714 89758985
Anti-cyclic citrullinated peptide antibody 30.12 9.72 390 852358 26831 89748868
Acute respiratory failure 29.80 9.72 259 852489 42659 89733040
Tuberculosis 29.57 9.72 211 852537 12338 89763361
Circulatory collapse 29.54 9.72 127 852621 24777 89750922
Complication of device removal 29.41 9.72 11 852737 6244 89769455
Mania 29.38 9.72 55 852693 14069 89761630
Wheelchair user 29.35 9.72 148 852600 7637 89768062
White blood cell count decreased 29.30 9.72 1279 851469 165830 89609869
Paralysis 29.28 9.72 39 852709 11439 89764260
Product prescribing error 29.26 9.72 165 852583 29980 89745719
Hospitalisation 29.22 9.72 950 851798 127150 89648549
Hyperlipidaemia 28.97 9.72 114 852634 22802 89752897
Inappropriate schedule of product administration 28.95 9.72 1135 851613 148798 89626901
Stevens-Johnson syndrome 28.94 9.72 160 852588 29216 89746483
Blood creatinine increased 28.66 9.72 730 852018 100656 89675043
Psychomotor hyperactivity 28.36 9.72 48 852700 12765 89762934
Lower limb fracture 28.35 9.72 1022 851726 83991 89691708
Product administration error 28.23 9.72 140 852608 26283 89749416
Heart rate decreased 28.19 9.72 681 852067 52824 89722875
Multiple fractures 28.15 9.72 170 852578 9392 89766307
Ventricular fibrillation 28.07 9.72 56 852692 13988 89761711
Sinus disorder 28.06 9.72 199 852549 34248 89741451
Transplant rejection 28.05 9.72 48 852700 12710 89762989
Blood creatine phosphokinase increased 27.98 9.72 196 852552 33827 89741872
Asphyxia 27.96 9.72 16 852732 7087 89768612
Product administered to patient of inappropriate age 27.93 9.72 5 852743 4648 89771051
Cerebral haemorrhage 27.84 9.72 200 852548 34322 89741377
Metastases to lung 27.67 9.72 69 852679 15922 89759777
Labelled drug-drug interaction medication error 27.58 9.72 60 852688 14522 89761177
Toxic epidermal necrolysis 27.44 9.72 186 852562 32342 89743357
Joint dislocation 27.42 9.72 580 852168 44002 89731697
Asthma 27.38 9.72 1935 850813 240225 89535474
Ascites 27.31 9.72 302 852446 47438 89728261
Laryngitis 27.05 9.72 647 852101 50106 89725593
Fear 27.03 9.72 74 852674 16548 89759151
X-ray abnormal 26.99 9.72 588 852160 44836 89730863
Bronchopulmonary aspergillosis 26.83 9.72 41 852707 11357 89764342
Myocarditis 26.79 9.72 56 852692 13750 89761949
Injection site reaction 26.68 9.72 1090 851658 90990 89684709
Disability 26.68 9.72 535 852213 40210 89735489
Heart rate increased 26.54 9.72 834 851914 112068 89663631
Epstein-Barr virus infection 26.54 9.72 35 852713 10309 89765390
Hepatic cirrhosis 26.41 9.72 781 851967 62472 89713227
Infusion site pain 26.38 9.72 96 852652 19642 89756057
Pulmonary oedema 26.27 9.72 418 852330 61662 89714037
Acute respiratory distress syndrome 26.25 9.72 160 852588 28526 89747173
Maternal drugs affecting foetus 26.16 9.72 107 852641 5048 89770651
Tenderness 26.07 9.72 376 852372 26492 89749207
Toxic skin eruption 25.82 9.72 70 852678 15704 89759995
Skin toxicity 25.66 9.72 16 852732 6763 89768936
Hypokalaemia 25.65 9.72 991 851757 130125 89645574
Electrocardiogram QRS complex prolonged 25.60 9.72 19 852729 7329 89768370
Sneezing 25.59 9.72 170 852578 29699 89746000
Maternal exposure before pregnancy 25.54 9.72 187 852561 11026 89764673
Blood bilirubin increased 25.26 9.72 274 852474 43196 89732503
Breast cancer female 25.17 9.72 65 852683 14821 89760878
Lymphopenia 25.16 9.72 120 852628 22761 89752938
Sexual dysfunction 25.15 9.72 7 852741 4797 89770902
Transaminases increased 25.14 9.72 226 852522 36966 89738733
Bronchopulmonary aspergillosis allergic 25.03 9.72 3 852745 3763 89771936
Dry mouth 25.00 9.72 2034 850714 182025 89593674
Ventricular septal defect 24.93 9.72 109 852639 5298 89770401
Product prescribing issue 24.87 9.72 23 852725 7956 89767743
Premature rupture of membranes 24.84 9.72 111 852637 5447 89770252
Jaundice cholestatic 24.74 9.72 35 852713 10008 89765691
Neuroleptic malignant syndrome 24.70 9.72 67 852681 15029 89760670
Throat tightness 24.67 9.72 169 852579 29315 89746384
Lupus-like syndrome 24.62 9.72 618 852130 48228 89727471
Proteinuria 24.54 9.72 124 852624 23167 89752532
Jaundice 24.50 9.72 192 852556 32325 89743374
International normalised ratio increased 24.48 9.72 306 852442 47010 89728689
Drug effective for unapproved indication 24.47 9.72 23 852725 7895 89767804
Dysphonia 24.33 9.72 432 852316 62652 89713047
Renal tubular necrosis 24.27 9.72 64 852684 14491 89761208
Urinary incontinence 24.22 9.72 231 852517 37335 89738364
Infective pulmonary exacerbation of cystic fibrosis 24.17 9.72 37 852711 10242 89765457
Bradypnoea 23.99 9.72 7 852741 4651 89771048
Drug tolerance 23.91 9.72 266 852482 17650 89758049
Clostridium difficile colitis 23.90 9.72 150 852598 26556 89749143
Fall 23.81 9.72 4078 848670 477732 89297967
Body temperature decreased 23.79 9.72 335 852413 23481 89752218
Rash maculo-papular 23.79 9.72 258 852490 40675 89735024
Sinus bradycardia 23.62 9.72 81 852667 16871 89758828
Colitis microscopic 23.61 9.72 43 852705 11116 89764583
Pseudomonas infection 23.56 9.72 67 852681 14798 89760901
Onychomycosis 23.56 9.72 488 852260 36888 89738811
Respiratory tract congestion 23.49 9.72 156 852592 27254 89748445
Pallor 23.36 9.72 207 852541 33958 89741741
Dyspnoea exertional 23.34 9.72 510 852238 71778 89703921
Total lung capacity increased 23.32 9.72 9 852739 5012 89770687
Enthesopathy 23.26 9.72 160 852588 9244 89766455
Blood pressure diastolic increased 23.26 9.72 204 852544 12702 89762997
Epistaxis 23.24 9.72 616 852132 84509 89691190
Device breakage 23.23 9.72 62 852686 13982 89761717
Acute chest syndrome 23.17 9.72 40 852708 1108 89774591
Sleep disorder 22.96 9.72 2163 850585 195867 89579832
Anosognosia 22.93 9.72 3 852745 3519 89772180
Psoriasis 22.92 9.72 1650 851098 146104 89629595
Ketoacidosis 22.90 9.72 12 852736 5583 89770116
Atrial tachycardia 22.86 9.72 14 852734 5976 89769723
Hot flush 22.74 9.72 408 852340 59080 89716619
Middle insomnia 22.70 9.72 81 852667 16670 89759029
Schizoaffective disorder 22.66 9.72 10 852738 5137 89770562
Product adhesion issue 22.62 9.72 10 852738 5132 89770567
Complication associated with device 22.57 9.72 100 852648 19349 89756350
Osteonecrosis of jaw 22.51 9.72 247 852501 38856 89736843
Dysmorphism 22.50 9.72 64 852684 2504 89773195
Mood altered 22.50 9.72 84 852664 17060 89758639
Rales 22.48 9.72 75 852673 15752 89759947
Incorrect dose administered 22.39 9.72 568 852180 78362 89697337
Blood test abnormal 22.39 9.72 111 852637 20841 89754858
Blindness 22.37 9.72 152 852596 26416 89749283
Pulseless electrical activity 22.13 9.72 31 852717 8901 89766798
Haemorrhage intracranial 22.12 9.72 71 852677 15091 89760608
Paranoia 22.10 9.72 56 852692 12852 89762847
Femur fracture 22.05 9.72 579 852169 45503 89730196
Cyanosis 22.00 9.72 101 852647 19354 89756345
Device issue 21.98 9.72 175 852573 29362 89746337
Bradykinesia 21.84 9.72 19 852729 6769 89768930
Product storage error 21.76 9.72 107 852641 20134 89755565
Limb deformity 21.72 9.72 87 852661 4065 89771634
Cardiomyopathy 21.62 9.72 107 852641 20099 89755600
Hypomagnesaemia 21.62 9.72 222 852526 35366 89740333
Lung disorder 21.60 9.72 1664 851084 148219 89627480
Leukocytosis 21.53 9.72 187 852561 30803 89744896
Sleep disorder due to a general medical condition 21.43 9.72 294 852454 44444 89731255
Myopathy 21.37 9.72 61 852687 13457 89762242
Dissociation 21.35 9.72 19 852729 6696 89769003
Respiratory acidosis 21.31 9.72 27 852721 8092 89767607
Stress cardiomyopathy 21.31 9.72 60 852688 13295 89762404
Latent tuberculosis 21.23 9.72 69 852679 2907 89772792
Lupus vulgaris 21.23 9.72 565 852183 44494 89731205
Acute myeloid leukaemia 21.12 9.72 111 852637 20529 89755170
Inappropriate antidiuretic hormone secretion 21.04 9.72 103 852645 19402 89756297
Hallucination, visual 21.03 9.72 129 852619 22963 89752736
Creatinine renal clearance increased 20.88 9.72 3 852745 3278 89772421
Malignant mediastinal neoplasm 20.87 9.72 43 852705 1365 89774334
Smear cervix abnormal 20.77 9.72 71 852677 3071 89772628
Sleep terror 20.74 9.72 8 852740 4456 89771243
Therapy interrupted 20.66 9.72 339 852409 49769 89725930
Atrioventricular block complete 20.59 9.72 38 852710 9773 89765926
Anti-neutrophil cytoplasmic antibody positive vasculitis 20.57 9.72 6 852742 3987 89771712
Nervousness 20.46 9.72 213 852535 33843 89741856
Graft versus host disease 20.44 9.72 28 852720 8116 89767583
Cytomegalovirus infection reactivation 20.41 9.72 26 852722 7774 89767925
Renal injury 20.34 9.72 41 852707 10202 89765497
Adenovirus infection 20.31 9.72 9 852739 4613 89771086
Atrial septal defect 20.31 9.72 140 852608 8094 89767605
Deep vein thrombosis 20.29 9.72 682 852066 90938 89684761
Therapeutic response shortened 20.22 9.72 129 852619 22750 89752949
Sputum discoloured 20.12 9.72 111 852637 20280 89755419
Haemodynamic instability 20.05 9.72 51 852697 11688 89764011
Device related infection 20.02 9.72 151 852597 25635 89750064
Hypoaesthesia 19.96 9.72 3306 849442 310904 89464795
Body temperature increased 19.95 9.72 298 852450 44412 89731287
Human herpesvirus 6 infection 19.94 9.72 4 852744 3428 89772271
Toxic encephalopathy 19.80 9.72 32 852716 8667 89767032
Agranulocytosis 19.79 9.72 222 852526 34780 89740919
Haemoptysis 19.77 9.72 209 852539 33111 89742588
Acute graft versus host disease in skin 19.77 9.72 10 852738 4746 89770953
Progressive multifocal leukoencephalopathy 19.71 9.72 78 852670 15577 89760122
Sleep apnoea syndrome 19.71 9.72 197 852551 31550 89744149
Lymphoedema 19.65 9.72 65 852683 13688 89762011
Blood alkaline phosphatase increased 19.59 9.72 326 852422 47753 89727946
Pharyngeal swelling 19.58 9.72 40 852708 9904 89765795
Retinitis 19.51 9.72 487 852261 37971 89737728
Presyncope 19.48 9.72 198 852550 31607 89744092
Rotator cuff repair 19.44 9.72 59 852689 2395 89773304
Multiple allergies 19.37 9.72 75 852673 15071 89760628
Respiration abnormal 19.37 9.72 28 852720 7935 89767764
Breast cancer metastatic 19.31 9.72 75 852673 15057 89760642
Onychomadesis 19.22 9.72 568 852180 45430 89730269
Anuria 19.19 9.72 73 852675 14745 89760954
Rheumatoid lung 19.14 9.72 83 852665 4020 89771679
Laryngospasm 19.12 9.72 4 852744 3329 89772370
Anosmia 19.06 9.72 40 852708 9808 89765891
Acute myocardial infarction 19.06 9.72 223 852525 34667 89741032
Exostosis 19.02 9.72 644 852104 52490 89723209
Hereditary angioedema 19.01 9.72 37 852711 9328 89766371
Skin plaque 18.90 9.72 41 852707 9934 89765765
Diplopia 18.75 9.72 176 852572 28538 89747161
Pain in extremity 18.75 9.72 4643 848105 445886 89329813
Generalised tonic-clonic seizure 18.71 9.72 224 852524 34679 89741020
Feeling hot 18.64 9.72 575 852173 77433 89698266
Acute pulmonary oedema 18.47 9.72 39 852709 9541 89766158
Pruritus 18.38 9.72 4670 848078 536855 89238844
Affective disorder 18.37 9.72 28 852720 7765 89767934
Pruritus genital 18.33 9.72 10 852738 4548 89771151
Hyperlactacidaemia 18.26 9.72 8 852740 4128 89771571
Trigeminal neuralgia 18.22 9.72 8 852740 4123 89771576
Antinuclear antibody positive 18.21 9.72 149 852599 9092 89766607
Pulmonary arterial hypertension 18.20 9.72 158 852590 26029 89749670
Placental disorder 18.05 9.72 44 852704 1567 89774132
Multiple sclerosis 18.03 9.72 171 852577 27669 89748030
Body height below normal 18.00 9.72 53 852695 2115 89773584
Genital haemorrhage 18.00 9.72 34 852714 8668 89767031
Ankylosing spondylitis 17.99 9.72 196 852552 12937 89762762
Transplant dysfunction 17.96 9.72 14 852734 5268 89770431
Infusion site erythema 17.93 9.72 67 852681 13603 89762096
Dysuria 17.79 9.72 262 852486 39139 89736560
Gastroenteritis viral 17.73 9.72 392 852356 29963 89745736
Maternal exposure during delivery 17.69 9.72 7 852741 3839 89771860
Skin ulcer 17.69 9.72 606 852142 49469 89726230
Synovial disorder 17.67 9.72 67 852681 3051 89772648
Post-traumatic stress disorder 17.62 9.72 23 852725 6805 89768894
Lacrimation increased 17.62 9.72 166 852582 26896 89748803
Neutrophilia 17.60 9.72 17 852731 5761 89769938
Tubulointerstitial nephritis 17.57 9.72 153 852595 25190 89750509
Personality change 17.55 9.72 26 852722 7295 89768404
Glycosylated haemoglobin increased 17.47 9.72 81 852667 15481 89760218
Developmental hip dysplasia 17.45 9.72 43 852705 1542 89774157
Diabetes mellitus 17.31 9.72 471 852277 64404 89711295
Abdominal pain 17.31 9.72 3371 849377 392350 89383349
Seronegative arthritis 17.23 9.72 254 852494 17980 89757719
Nail operation 17.19 9.72 48 852700 1858 89773841
Synovial fluid analysis 17.18 9.72 62 852686 2756 89772943
Rash macular 17.14 9.72 192 852556 30088 89745611
Hyperpyrexia 16.99 9.72 12 852736 4749 89770950
Tenosynovitis stenosans 16.96 9.72 78 852670 3875 89771824
Acute coronary syndrome 16.94 9.72 49 852699 10764 89764935
Foetal anticonvulsant syndrome 16.94 9.72 26 852722 651 89775048
Insurance issue 16.92 9.72 50 852698 10908 89764791
Melaena 16.91 9.72 228 852520 34569 89741130
Aspiration 16.85 9.72 83 852665 15610 89760089
Procedural pain 16.79 9.72 217 852531 33143 89742556
Eye swelling 16.76 9.72 186 852562 29200 89746499
Cardiac disorder 16.74 9.72 407 852341 56465 89719234
Pain of skin 16.73 9.72 86 852662 15996 89759703
Vascular device infection 16.73 9.72 57 852691 11895 89763804
Blood lactic acid increased 16.70 9.72 36 852712 8742 89766957
Device malfunction 16.69 9.72 122 852626 20855 89754844
Treatment noncompliance 16.68 9.72 365 852383 51362 89724337
Gastrointestinal haemorrhage 16.59 9.72 687 852061 89561 89686138
Blood parathyroid hormone decreased 16.59 9.72 182 852566 12034 89763665
Spinal stenosis 16.58 9.72 243 852505 17181 89758518
Capillary leak syndrome 16.55 9.72 3 852745 2764 89772935
Metastasis 16.54 9.72 20 852728 6117 89769582
Cholelithiasis 16.51 9.72 372 852376 52134 89723565
Loose body in joint 16.47 9.72 39 852709 1363 89774336
Acidosis 16.33 9.72 63 852685 12673 89763026
Loss of employment 16.31 9.72 4 852744 2983 89772716
Product quality issue 16.30 9.72 596 852152 78729 89696970
Bone lesion 16.29 9.72 22 852726 6415 89769284
Glomerular filtration rate decreased 16.26 9.72 93 852655 16839 89758860
Chronic obstructive pulmonary disease 16.25 9.72 550 852198 73279 89702420
Neck mass 16.21 9.72 76 852672 3806 89771893
Product substitution issue 16.19 9.72 101 852647 17907 89757792
Metastases to lymph nodes 16.19 9.72 56 852692 11633 89764066
Cleft lip and palate 16.13 9.72 27 852721 729 89774970
Coronary artery disease 16.09 9.72 221 852527 33402 89742297
Hallucinations, mixed 16.08 9.72 19 852729 5870 89769829
Hyperthermia 16.07 9.72 47 852701 10288 89765411
Blood pressure inadequately controlled 16.03 9.72 21 852727 6203 89769496
Blood pressure decreased 16.01 9.72 560 852188 74335 89701364
Maternal exposure timing unspecified 16.00 9.72 299 852449 22184 89753515
Postoperative wound infection 15.98 9.72 195 852553 13231 89762468
Visual acuity reduced 15.93 9.72 142 852606 23268 89752431
Localised infection 15.86 9.72 421 852327 33141 89742558
Red blood cell sedimentation rate 15.80 9.72 86 852662 4572 89771127
Cholecystitis chronic 15.79 9.72 44 852704 9782 89765917
Anhedonia 15.67 9.72 55 852693 11376 89764323
Abortion incomplete 15.66 9.72 5 852743 3135 89772564
Intracranial pressure increased 15.55 9.72 25 852723 6786 89768913
Product dose omission in error 15.48 9.72 121 852627 20382 89755317
Granuloma skin 15.38 9.72 161 852587 10519 89765180
Pancytopenia 15.37 9.72 1323 851425 118940 89656759
Chronic graft versus host disease 15.35 9.72 10 852738 4129 89771570
Skin lesion 15.34 9.72 253 852495 37112 89738587
Oliguria 15.33 9.72 50 852698 10574 89765125
Pregnancy with contraceptive device 15.33 9.72 15 852733 5051 89770648
Haematocrit decreased 15.22 9.72 508 852240 41324 89734375
Threatened labour 15.21 9.72 29 852719 869 89774830
Pre-eclampsia 15.19 9.72 165 852583 10883 89764816
Hepatitis acute 15.18 9.72 52 852696 10835 89764864
Antibody test positive 15.14 9.72 62 852686 2927 89772772
Temperature intolerance 15.11 9.72 60 852688 11970 89763729
Amenorrhoea 15.02 9.72 58 852690 11664 89764035
Infusion site swelling 15.01 9.72 58 852690 11662 89764037
Congenital arterial malformation 14.97 9.72 17 852731 314 89775385
Haemoglobin decreased 14.94 9.72 1742 851006 160214 89615485
Amyloid arthropathy 14.85 9.72 42 852706 1638 89774061
Candida infection 14.85 9.72 228 852520 33829 89741870
Fracture 14.83 9.72 291 852457 21785 89753914
Hyperbilirubinaemia 14.79 9.72 74 852674 13862 89761837
Impaired gastric emptying 14.78 9.72 66 852682 12743 89762956
Hepatitis cholestatic 14.77 9.72 37 852711 8524 89767175
Carotid artery occlusion 14.75 9.72 23 852725 6319 89769380
Potentiating drug interaction 14.69 9.72 19 852729 5643 89770056
Hallucination, auditory 14.67 9.72 89 852659 15886 89759813
Stillbirth 14.66 9.72 120 852628 7323 89768376
Skin papilloma 14.65 9.72 97 852651 5533 89770166
Impaired quality of life 14.63 9.72 143 852605 23001 89752698
Synovial cyst 14.57 9.72 172 852576 11580 89764119
Ankle arthroplasty 14.56 9.72 59 852689 2772 89772927
Tumour marker increased 14.54 9.72 20 852728 5787 89769912
Extra dose administered 14.52 9.72 41 852707 9077 89766622
Rhinovirus infection 14.47 9.72 21 852727 5942 89769757
Graft versus host disease in gastrointestinal tract 14.46 9.72 12 852736 4376 89771323
Injection site pruritus 14.40 9.72 632 852116 53202 89722497
Lymphatic fistula 14.39 9.72 38 852710 1423 89774276
Disturbance in social behaviour 14.37 9.72 11 852737 4177 89771522
Uterine perforation 14.36 9.72 31 852717 7523 89768176
Exercise tolerance decreased 14.34 9.72 31 852717 7520 89768179
Breast feeding 14.33 9.72 28 852720 855 89774844
Device deployment issue 14.32 9.72 15 852733 4894 89770805
Ataxia 14.32 9.72 105 852643 17937 89757762
Polyhydramnios 14.30 9.72 54 852694 2454 89773245
Pericardial effusion 14.28 9.72 252 852496 36581 89739118
Nephropathy toxic 14.27 9.72 66 852682 12622 89763077
Pulmonary tuberculosis 14.27 9.72 86 852662 4748 89770951
Thrombosis 14.24 9.72 554 852194 72697 89703002
Human antichimeric antibody positive 14.21 9.72 43 852705 1743 89773956
Limb reduction defect 14.17 9.72 23 852725 605 89775094
Urinary retention 14.07 9.72 260 852488 37484 89738215
Reversible cerebral vasoconstriction syndrome 13.98 9.72 11 852737 4119 89771580
Haematemesis 13.96 9.72 228 852520 33498 89742201
Metabolic disorder 13.91 9.72 31 852717 7439 89768260
Hypothyroidism 13.84 9.72 387 852361 52740 89722959
Subarachnoid haemorrhage 13.83 9.72 105 852643 17799 89757900
Klebsiella infection 13.81 9.72 50 852698 10247 89765452
Pneumonia viral 13.81 9.72 40 852708 8783 89766916
Atrioventricular block 13.77 9.72 40 852708 8775 89766924
Hypertelorism 13.76 9.72 21 852727 523 89775176
Ear infection 13.68 9.72 795 851953 68980 89706719
Wound infection pseudomonas 13.62 9.72 46 852702 1977 89773722
Staphylococcal infection 13.62 9.72 349 852399 48090 89727609
Femoral hernia incarcerated 13.62 9.72 38 852710 1470 89774229
Varicella zoster virus infection 13.54 9.72 10 852738 3867 89771832
Pulmonary haemorrhage 13.54 9.72 35 852713 7978 89767721
Hypoventilation 13.50 9.72 18 852730 5278 89770421
Erythema of eyelid 13.50 9.72 7 852741 3276 89772423
Clear cell renal cell carcinoma 13.48 9.72 39 852709 1541 89774158
Osteonecrosis 13.47 9.72 170 852578 26071 89749628
Nystagmus 13.45 9.72 30 852718 7197 89768502
Graft versus host disease in skin 13.38 9.72 10 852738 3843 89771856
Increased appetite 13.35 9.72 61 852687 11704 89763995
Blepharospasm 13.34 9.72 644 852104 54801 89720898
Hyperprolactinaemia 13.32 9.72 19 852729 5414 89770285
X-ray gastrointestinal tract abnormal 13.31 9.72 5 852743 9 89775690
Restless legs syndrome 13.31 9.72 141 852607 22329 89753370
Abdominal distension 13.25 9.72 1053 851695 129548 89646151
Retrognathia 13.19 9.72 21 852727 543 89775156
Terminal state 13.17 9.72 5 852743 2813 89772886
Pulmonary congestion 13.17 9.72 118 852630 19315 89756384
Hypotonia 13.11 9.72 59 852689 11367 89764332
Respiratory disorder 13.09 9.72 488 852260 64328 89711371
Blood glucose decreased 13.09 9.72 149 852599 23280 89752419
Skin fissures 12.97 9.72 129 852619 20680 89755019
Pancreatitis 12.95 9.72 531 852217 69295 89706404
Dermatitis exfoliative 12.95 9.72 20 852728 5516 89770183
Brain injury 12.92 9.72 34 852714 7704 89767995
Hyperreflexia 12.92 9.72 27 852721 6630 89769069
Endophthalmitis 12.91 9.72 15 852733 4670 89771029
Bundle branch block left 12.90 9.72 35 852713 7850 89767849
Finger deformity 12.88 9.72 403 852345 32494 89743205
Device physical property issue 12.85 9.72 5 852743 2771 89772928
Subacute cutaneous lupus erythematosus 12.82 9.72 9 852739 3573 89772126
Altered state of consciousness 12.78 9.72 214 852534 31318 89744381
Panniculitis 12.73 9.72 199 852549 14259 89761440
Drug screen positive 12.72 9.72 10 852738 3747 89771952
Purpura 12.71 9.72 84 852664 14694 89761005
Poor quality device used 12.66 9.72 3 852745 2290 89773409
Tenosynovitis 12.64 9.72 200 852548 14367 89761332
Cerebral haematoma 12.63 9.72 13 852735 4276 89771423
Lip oedema 12.63 9.72 15 852733 4624 89771075
Hypertransaminasaemia 12.61 9.72 92 852656 15733 89759966
Bone density increased 12.59 9.72 27 852721 882 89774817
Wrong product administered 12.56 9.72 34 852714 7631 89768068
Bundle branch block right 12.47 9.72 20 852728 5433 89770266
Spondylitis 12.43 9.72 195 852553 13983 89761716
Eyelid oedema 12.39 9.72 61 852687 11473 89764226
Incorrect product administration duration 12.37 9.72 119 852629 19203 89756496
Hypothalamo-pituitary disorder 12.33 9.72 3 852745 2249 89773450
Nasal obstruction 12.31 9.72 53 852695 2559 89773140
Anger 12.31 9.72 77 852671 13643 89762056
Crohn's disease 12.28 9.72 83 852665 4768 89770931
Arthritis infective 12.23 9.72 122 852626 7870 89767829
Eye pain 12.22 9.72 319 852429 43849 89731850
Head injury 12.21 9.72 213 852535 30975 89744724
International normalised ratio fluctuation 12.13 9.72 7 852741 3086 89772613
Needle issue 12.09 9.72 79 852669 13855 89761844
Epstein-Barr virus associated lymphoproliferative disorder 12.03 9.72 5 852743 2662 89773037
Immunisation 12.01 9.72 3 852745 2210 89773489
Right ventricular failure 12.00 9.72 119 852629 19086 89756613
Intraocular pressure increased 11.97 9.72 31 852717 7062 89768637
Scleritis 11.94 9.72 87 852661 5121 89770578
Fracture delayed union 11.92 9.72 51 852697 2455 89773244
Speech disorder developmental 11.92 9.72 27 852721 916 89774783
Pulmonary alveolar haemorrhage 11.92 9.72 24 852724 5974 89769725
Sensitisation 11.91 9.72 13 852735 4162 89771537
Cross sensitivity reaction 11.88 9.72 6 852742 2851 89772848
Cell death 11.86 9.72 7 852741 3048 89772651
Infusion site pruritus 11.86 9.72 29 852719 6736 89768963
Nasal oedema 11.83 9.72 104 852644 6480 89769219
Immune-mediated myositis 11.82 9.72 4 852744 2417 89773282
Device leakage 11.82 9.72 51 852697 9940 89765759
Gastroschisis 11.82 9.72 17 852731 401 89775298
Malignant melanoma 11.81 9.72 175 852573 12401 89763298
Occult blood 11.81 9.72 33 852715 1278 89774421
Type I hypersensitivity 11.78 9.72 13 852735 4142 89771557
Hepatic necrosis 11.76 9.72 27 852721 6411 89769288
Hepatitis B reactivation 11.75 9.72 12 852736 3962 89771737
Short stature 11.75 9.72 29 852719 1041 89774658
Exomphalos 11.71 9.72 20 852728 549 89775150
Hypokinesia 11.68 9.72 93 852655 15604 89760095
Laryngeal oedema 11.67 9.72 30 852718 6851 89768848
Myocardial ischaemia 11.65 9.72 79 852669 13735 89761964
Walking aid user 11.63 9.72 426 852322 35080 89740619
Incoherent 11.62 9.72 18 852730 4959 89770740
Implant site pain 11.62 9.72 5 852743 2607 89773092
Hypertensive crisis 11.61 9.72 109 852639 17675 89758024
Haemorrhage in pregnancy 11.61 9.72 46 852702 2139 89773560
Diabetes insipidus 11.59 9.72 8 852740 3204 89772495
Full blood count abnormal 11.58 9.72 259 852489 36338 89739361
Atrioventricular block second degree 11.49 9.72 15 852733 4437 89771262
Burning sensation 11.46 9.72 484 852264 62968 89712731
Major depression 11.40 9.72 52 852696 9983 89765716
Nail injury 11.40 9.72 24 852724 774 89774925
Visual impairment 11.39 9.72 1081 851667 131284 89644415
Systemic inflammatory response syndrome 11.37 9.72 28 852720 6488 89769211
Osteolysis 11.34 9.72 10 852738 3540 89772159
Facial pain 11.31 9.72 75 852673 13107 89762592
Abnormal dreams 11.26 9.72 61 852687 11196 89764503
Device use issue 11.23 9.72 11 852737 3702 89771997
Cholinergic syndrome 11.21 9.72 22 852726 674 89775025
Troponin increased 11.17 9.72 76 852672 13205 89762494
Skin neoplasm excision 11.15 9.72 39 852709 1707 89773992
Catheter site erythema 11.14 9.72 18 852730 4876 89770823
Skin swelling 11.09 9.72 29 852719 6585 89769114
Wrong technique in device usage process 11.04 9.72 24 852724 5811 89769888
Retching 11.03 9.72 121 852627 19038 89756661
Corneal opacity congenital 11.03 9.72 3 852745 0 89775699
Cardiac monitoring abnormal 11.03 9.72 3 852745 0 89775699
Pulmonary hypertension 11.01 9.72 310 852438 42213 89733486
Blood phosphorus decreased 11.01 9.72 19 852729 5015 89770684
Pharyngeal oedema 11.00 9.72 80 852668 13691 89762008
Kidney transplant rejection 10.93 9.72 18 852730 4839 89770860
Hypoglycaemia neonatal 10.86 9.72 29 852719 1093 89774606
Polyuria 10.84 9.72 53 852695 9987 89765712
Benign ovarian tumour 10.78 9.72 18 852730 485 89775214
Cyst rupture 10.74 9.72 24 852724 807 89774892
Congenital cerebral cyst 10.73 9.72 13 852735 258 89775441
Lymph gland infection 10.71 9.72 19 852729 538 89775161
Gestational hypertension 10.70 9.72 57 852691 3005 89772694
Cushingoid 10.70 9.72 147 852601 10248 89765451
Immune effector cell-associated neurotoxicity syndrome 10.69 9.72 24 852724 5744 89769955
Electrolyte imbalance 10.68 9.72 158 852590 23587 89752112
Prescribed overdose 10.67 9.72 1062 851686 96563 89679136
Metastases to pleura 10.66 9.72 3 852745 2041 89773658
Hypercapnia 10.65 9.72 30 852718 6647 89769052
Central nervous system lesion 10.63 9.72 65 852683 11581 89764118
Breast cancer stage IV 10.61 9.72 3 852745 2035 89773664
Bronchial secretion retention 10.60 9.72 11 852737 3604 89772095
Ingrown hair 10.59 9.72 20 852728 595 89775104
Pseudomonal sepsis 10.59 9.72 15 852733 4287 89771412
Product availability issue 10.57 9.72 35 852713 7369 89768330
Poor quality sleep 10.53 9.72 166 852582 24527 89751172
Product residue present 10.52 9.72 15 852733 4276 89771423
Catheter site pain 10.52 9.72 23 852725 5556 89770143
Iritis 10.51 9.72 65 852683 3621 89772078
Sinus congestion 10.51 9.72 188 852560 27236 89748463
Venoocclusive disease 10.45 9.72 5 852743 2450 89773249
Oligoarthritis 10.44 9.72 19 852729 549 89775150
Folate deficiency 10.44 9.72 58 852690 3107 89772592
Unevaluable event 10.41 9.72 416 852332 54432 89721267
Inadequate analgesia 10.40 9.72 9 852739 3215 89772484
Injection site erythema 10.40 9.72 1069 851679 97433 89678266
Carbohydrate antigen 15-3 increased 10.37 9.72 3 852745 2004 89773695
Paraesthesia oral 10.32 9.72 223 852525 31436 89744263
Nervous system disorder 10.31 9.72 142 852606 21451 89754248
Ageusia 10.30 9.72 99 852649 15977 89759722
Embedded device 10.27 9.72 15 852733 4233 89771466
Alanine aminotransferase increased 10.24 9.72 966 851782 117372 89658327
Facial paralysis 10.23 9.72 95 852653 15439 89760260
Dyspepsia 10.23 9.72 2063 850685 196097 89579602
Blood iron increased 10.21 9.72 41 852707 1918 89773781
Inflammatory marker increased 10.19 9.72 132 852616 9082 89766617
Polydipsia 10.17 9.72 15 852733 4216 89771483
Bacteraemia 10.17 9.72 148 852600 22152 89753547
Scratch 10.13 9.72 53 852695 9813 89765886
Human anti-human antibody test 10.10 9.72 16 852732 412 89775287
Scan abnormal 10.09 9.72 20 852728 617 89775082
Ventricular hypokinesia 10.08 9.72 22 852726 5319 89770380
Defaecation disorder 10.01 9.72 25 852723 904 89774795
End stage renal disease 9.99 9.72 44 852704 8527 89767172
Sickle cell anaemia 9.99 9.72 20 852728 622 89775077
Silent thyroiditis 9.98 9.72 10 852738 159 89775540
Foetal distress syndrome 9.96 9.72 37 852711 1668 89774031
Non-small cell lung cancer 9.94 9.72 73 852675 4308 89771391
Tetany 9.92 9.72 6 852742 2578 89773121
Blood iron abnormal 9.91 9.72 14 852734 4006 89771693
Pancreatic steatosis 9.90 9.72 36 852712 1606 89774093
Oral pain 9.87 9.72 233 852515 32450 89743249
Pleural effusion 9.86 9.72 913 851835 111078 89664621
Learning disorder 9.86 9.72 24 852724 854 89774845
Cervical incompetence 9.86 9.72 20 852728 628 89775071
Delusion 9.84 9.72 83 852665 13757 89761942
Infection reactivation 9.84 9.72 3 852745 1937 89773762
Catheter site haemorrhage 9.84 9.72 12 852736 3656 89772043
Cleft palate 9.83 9.72 31 852717 1285 89774414
Nocardiosis 9.82 9.72 6 852742 2564 89773135
Euglycaemic diabetic ketoacidosis 9.79 9.72 28 852720 6173 89769526
Congenital anomaly 9.77 9.72 97 852651 6250 89769449
Joint lock 9.77 9.72 49 852699 2523 89773176
Intervertebral disc degeneration 9.75 9.72 222 852526 17052 89758647
Nail disorder 9.74 9.72 663 852085 58404 89717295
Incorrect dose administered by device 9.74 9.72 25 852723 5712 89769987

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Rheumatoid arthritis 497.60 10.45 943 274105 41497 42304790
Drug abuse 476.37 10.45 58 274990 104713 42241574
Toxicity to various agents 442.65 10.45 496 274552 228640 42117647
Completed suicide 334.71 10.45 103 274945 96362 42249925
Drug interaction 242.38 10.45 896 274152 266103 42080184
Foetal exposure during pregnancy 233.34 10.45 754 274294 46557 42299730
Psoriatic arthropathy 197.69 10.45 473 274575 24494 42321793
Drug ineffective 180.58 10.45 2924 272124 627273 41719014
Off label use 172.67 10.45 2993 272055 635342 41710945
Product use in unapproved indication 164.57 10.45 623 274425 183833 42162454
Intentional overdose 154.77 10.45 69 274979 51387 42294900
Arthralgia 142.60 10.45 1983 273065 203255 42143032
Interstitial lung disease 128.36 10.45 907 274141 77555 42268732
Sickle cell anaemia with crisis 128.09 10.45 158 274890 4732 42341555
Dysmorphism 115.28 10.45 124 274924 3192 42343095
Overdose 107.69 10.45 335 274713 104929 42241358
Coma 105.26 10.45 114 274934 53440 42292847
Acute kidney injury 95.40 10.45 1733 273315 365604 41980683
Psoriasis 94.06 10.45 586 274462 48018 42298269
Drug resistance 93.82 10.45 52 274996 34196 42312091
Drug dependence 89.09 10.45 38 275010 29056 42317231
Death 85.27 10.45 2353 272695 468832 41877455
Sedation 81.01 10.45 48 275000 30427 42315860
Joint swelling 80.42 10.45 730 274318 67292 42278995
Pulmonary fibrosis 76.30 10.45 358 274690 26323 42319964
Drug ineffective for unapproved indication 75.43 10.45 113 274935 46050 42300237
Enthesopathy 72.99 10.45 120 274928 4708 42341579
Arthritis 69.76 10.45 488 274560 41577 42304710
Small for dates baby 69.27 10.45 123 274925 5140 42341147
Musculoskeletal stiffness 68.82 10.45 621 274427 57144 42289143
Synovitis 68.64 10.45 239 274809 15328 42330959
Angioedema 68.41 10.45 105 274943 42372 42303915
Suicide attempt 67.70 10.45 121 274927 45979 42300308
Disease progression 66.20 10.45 600 274448 143056 42203231
Blood pressure fluctuation 65.55 10.45 345 274703 26563 42319724
Poisoning 62.37 10.45 10 275038 14689 42331598
Pulmonary vasculitis 62.27 10.45 130 274918 6136 42340151
Tenosynovitis 62.14 10.45 110 274938 4585 42341702
Pneumonia 62.11 10.45 3323 271725 418826 41927461
Suicidal ideation 61.63 10.45 137 274911 48024 42298263
Serotonin syndrome 61.56 10.45 46 275002 25799 42320488
Platelet count decreased 61.43 10.45 1245 273803 137336 42208951
Blood pressure systolic increased 61.02 10.45 348 274700 27620 42318667
Exposure during pregnancy 60.32 10.45 155 274893 8393 42337894
Premature baby 59.98 10.45 302 274746 22851 42323436
Drug reaction with eosinophilia and systemic symptoms 59.51 10.45 113 274935 41962 42304325
Neuritis 59.44 10.45 127 274921 6093 42340194
Respiratory symptom 59.30 10.45 182 274866 10924 42335363
C-reactive protein increased 58.16 10.45 647 274401 62913 42283374
Blood pressure systolic abnormal 57.65 10.45 117 274931 5411 42340876
Nodule 57.50 10.45 195 274853 12339 42333948
Intentional product misuse 57.11 10.45 206 274842 61694 42284593
Speech disorder developmental 56.92 10.45 72 274976 2213 42344074
Rhabdomyolysis 56.39 10.45 285 274763 77734 42268553
C-reactive protein abnormal 54.42 10.45 157 274891 9104 42337183
Pathogen resistance 52.83 10.45 6 275042 11444 42334843
Foetal anticonvulsant syndrome 52.81 10.45 51 274997 1151 42345136
Neonatal respiratory distress syndrome 52.50 10.45 100 274948 4413 42341874
Eosinophilic granulomatosis with polyangiitis 52.27 10.45 148 274900 8490 42337797
Hypermagnesaemia 51.83 10.45 30 275018 296 42345991
Arthropathy 51.82 10.45 348 274700 29249 42317038
Lactic acidosis 51.41 10.45 137 274911 45124 42301163
Psychotic disorder 50.17 10.45 69 274979 29139 42317148
Haemoglobin decreased 49.72 10.45 1162 273886 131309 42214978
Mite allergy 48.18 10.45 103 274945 4943 42341344
Sopor 47.77 10.45 13 275035 13189 42333098
Maternal exposure during pregnancy 47.66 10.45 125 274923 6853 42339434
No adverse event 47.50 10.45 114 274934 38907 42307380
Pain 46.43 10.45 1977 273071 242871 42103416
Blood pressure diastolic abnormal 46.25 10.45 114 274934 6014 42340273
Low birth weight baby 45.78 10.45 155 274893 9800 42336487
Mycotic allergy 45.74 10.45 99 274949 4792 42341495
Pancytopenia 45.47 10.45 1037 274011 116706 42229581
Alanine aminotransferase abnormal 45.02 10.45 99 274949 4845 42341442
Hypoglycaemia neonatal 44.70 10.45 62 274986 2088 42344199
Agitation 44.19 10.45 239 274809 64075 42282212
Drug use disorder 43.91 10.45 7 275041 10326 42335961
Loss of personal independence in daily activities 43.71 10.45 503 274545 49313 42296974
Spirometry abnormal 43.45 10.45 100 274948 5046 42341241
Dust allergy 43.26 10.45 102 274946 5230 42341057
Learning disorder 42.94 10.45 44 275004 1069 42345218
Acute hepatic failure 41.16 10.45 30 275018 17043 42329244
Maternal drugs affecting foetus 40.93 10.45 82 274966 3757 42342530
Conjunctivitis allergic 40.49 10.45 106 274942 5805 42340482
Bradycardia 40.24 10.45 355 274693 85129 42261158
Hypospadias 40.22 10.45 78 274970 3489 42342798
Non-small cell lung cancer 40.19 10.45 95 274953 4879 42341408
Therapy partial responder 40.02 10.45 42 275006 19979 42326308
Myelosuppression 39.10 10.45 132 274916 40329 42305958
Atrial septal defect 38.82 10.45 126 274922 7793 42338494
Toxic epidermal necrolysis 38.57 10.45 71 274977 26679 42319608
Cryptorchism 38.52 10.45 56 274992 1971 42344316
Autism spectrum disorder 38.26 10.45 69 274979 2919 42343368
Tachycardia 37.98 10.45 443 274605 100644 42245643
Substance abuse 37.92 10.45 6 275042 8899 42337388
Pain in extremity 37.87 10.45 1255 273793 149349 42196938
Blood pressure diastolic decreased 37.16 10.45 149 274899 10226 42336061
Multiple organ dysfunction syndrome 36.94 10.45 424 274624 96611 42249676
Osteoarthritis 36.92 10.45 277 274771 24128 42322159
Jaundice neonatal 36.84 10.45 57 274991 2122 42344165
Pruritus 35.96 10.45 935 274113 187836 42158451
Rheumatoid nodule 35.62 10.45 67 274981 2928 42343359
Maternal exposure during breast feeding 35.61 10.45 47 275001 1508 42344779
Neurological symptom 35.40 10.45 143 274905 9848 42336439
Drug withdrawal syndrome 34.95 10.45 53 274995 21496 42324791
Lung neoplasm malignant 34.65 10.45 227 274821 18920 42327367
Aggression 34.42 10.45 157 274891 44006 42302281
Syndactyly 34.21 10.45 36 275012 903 42345384
Nasopharyngitis 34.05 10.45 745 274303 83251 42263036
Grip strength decreased 33.98 10.45 73 274975 3515 42342772
Intentional self-injury 33.77 10.45 29 275019 15173 42331114
Cardiac arrest 33.77 10.45 499 274549 108821 42237466
Joint effusion 33.71 10.45 99 274949 5798 42340489
Heart rate decreased 32.55 10.45 370 274678 36162 42310125
Blood pressure diastolic increased 32.39 10.45 103 274945 6302 42339985
Respiratory arrest 32.30 10.45 86 274962 28338 42317949
Neuroleptic malignant syndrome 31.84 10.45 56 274992 21416 42324871
Haematocrit decreased 31.76 10.45 355 274693 34553 42311734
Metabolic acidosis 31.73 10.45 200 274848 51658 42294629
Neutrophil count decreased 31.56 10.45 580 274468 62835 42283452
White blood cell count decreased 31.18 10.45 933 274115 109463 42236824
Joint laxity 30.75 10.45 24 275024 402 42345885
Renal failure 30.61 10.45 700 274348 143026 42203261
Neurotoxicity 30.48 10.45 67 274981 23584 42322703
Tongue disorder 30.42 10.45 90 274958 5293 42340994
Accidental exposure to product 30.41 10.45 53 274995 20340 42325947
Ventricular septal defect 30.25 10.45 79 274969 4320 42341967
Mucormycosis 29.99 10.45 5 275043 7138 42339149
Weight decreased 29.66 10.45 1633 273415 206315 42139972
Hand deformity 29.40 10.45 71 274977 3697 42342590
Infusion related reaction 29.17 10.45 553 274495 60253 42286034
Exposure via breast milk 28.95 10.45 55 274993 2422 42343865
Foot deformity 28.90 10.45 85 274963 4983 42341304
Total lung capacity abnormal 28.74 10.45 78 274970 4365 42341922
Normochromic normocytic anaemia 28.67 10.45 125 274923 8906 42337381
Aspergillus infection 28.65 10.45 36 275012 15801 42330486
Red blood cell count decreased 28.55 10.45 330 274718 32385 42313902
Respiratory depression 28.17 10.45 49 274999 18819 42327468
Urticaria 27.98 10.45 324 274724 73712 42272575
Wrong technique in product usage process 27.35 10.45 162 274886 42473 42303814
Withdrawal syndrome 27.34 10.45 33 275015 14742 42331545
Rebound effect 27.20 10.45 7 275041 7372 42338915
Arteriosclerosis 27.11 10.45 204 274844 17785 42328502
Immune reconstitution inflammatory syndrome 26.92 10.45 16 275032 10127 42336160
Bradycardia neonatal 26.73 10.45 38 275010 1310 42344977
Inflammation 26.73 10.45 335 274713 33512 42312775
Syringe issue 26.47 10.45 11 275037 8545 42337742
Serum ferritin increased 26.11 10.45 104 274944 7115 42339172
Knee arthroplasty 25.97 10.45 119 274929 8662 42337625
Polyomavirus-associated nephropathy 25.76 10.45 3 275045 5612 42340675
Polyarthritis 25.74 10.45 82 274966 5022 42341265
Akathisia 25.67 10.45 18 275030 10433 42335854
Acute chest syndrome 25.65 10.45 33 275015 1032 42345255
Arteriosclerosis coronary artery 25.50 10.45 207 274841 18470 42327817
Plagiocephaly 25.43 10.45 25 275023 577 42345710
Hypermobility syndrome 25.23 10.45 20 275028 343 42345944
Cytomegalovirus infection reactivation 25.23 10.45 21 275027 11157 42335130
Pulmonary alveolar haemorrhage 25.21 10.45 173 274875 14643 42331644
Body temperature decreased 24.95 10.45 169 274879 14244 42332043
Hypothyroidism 24.67 10.45 316 274732 31768 42314519
Suspected suicide 24.61 10.45 5 275043 6194 42340093
Respiratory disorder neonatal 24.60 10.45 45 275003 1925 42344362
Mucocutaneous ulceration 24.52 10.45 23 275025 500 42345787
Peripheral swelling 24.17 10.45 758 274290 89512 42256775
Adenovirus infection 24.08 10.45 7 275041 6802 42339485
Cardiac murmur 24.06 10.45 153 274895 12622 42333665
Hepatic function abnormal 24.06 10.45 467 274581 51100 42295187
Cardiotoxicity 23.97 10.45 9 275039 7436 42338851
Finger deformity 23.86 10.45 40 275008 1595 42344692
Squamous cell carcinoma of lung 23.83 10.45 48 275000 2208 42344079
Developmental delay 23.81 10.45 59 274989 3123 42343164
Congenital hand malformation 23.70 10.45 25 275023 629 42345658
Anal fissure 23.59 10.45 81 274967 5158 42341129
Wound 23.52 10.45 190 274858 16927 42329360
Dysgraphia 23.45 10.45 51 274997 2477 42343810
Red blood cell sedimentation rate increased 23.32 10.45 126 274922 9798 42336489
Foetal growth restriction 23.19 10.45 81 274967 5202 42341085
Colitis ulcerative 22.82 10.45 264 274784 25911 42320376
Cytomegalovirus infection 22.77 10.45 119 274929 32187 42314100
Large for dates baby 22.69 10.45 29 275019 901 42345386
Caesarean section 22.47 10.45 45 275003 2061 42344226
Venoocclusive liver disease 22.46 10.45 20 275028 10282 42336005
Myalgia 22.45 10.45 461 274587 95619 42250668
Basal cell carcinoma 22.44 10.45 235 274813 22498 42323789
Exposure to toxic agent 22.17 10.45 3 275045 5001 42341286
Post transplant lymphoproliferative disorder 22.02 10.45 16 275032 9104 42337183
Haematotoxicity 22.00 10.45 23 275025 10962 42335325
Drug withdrawal syndrome neonatal 21.88 10.45 71 274977 4390 42341897
Anaphylactic shock 21.86 10.45 78 274970 23439 42322848
Diaphragmatic disorder 21.78 10.45 33 275015 1206 42345081
Talipes 21.76 10.45 46 275002 2190 42344097
BK virus infection 21.75 10.45 15 275033 8769 42337518
Dermatitis atopic 21.61 10.45 29 275019 12375 42333912
Ultrasound antenatal screen 21.22 10.45 22 275026 542 42345745
Device leakage 21.21 10.45 21 275027 10264 42336023
Muscle twitching 21.08 10.45 27 275021 11753 42334534
Agitation neonatal 20.92 10.45 35 275013 1393 42344894
Liver disorder 20.92 10.45 366 274682 39278 42307009
Drug dose omission by device 20.91 10.45 6 275042 5880 42340407
Graft versus host disease in gastrointestinal tract 20.73 10.45 4 275044 5139 42341148
Acute graft versus host disease in skin 20.73 10.45 11 275037 7413 42338874
Lung disorder 20.69 10.45 429 274619 47494 42298793
Haematochezia 20.50 10.45 508 274540 57928 42288359
Sexual dysfunction 20.50 10.45 9 275039 6766 42339521
Multiple-drug resistance 20.22 10.45 11 275037 7311 42338976
Hydrops foetalis 20.18 10.45 27 275021 878 42345409
Eosinophilia 20.06 10.45 127 274921 32772 42313515
Catarrh 19.89 10.45 84 274964 5902 42340385
Agranulocytosis 19.80 10.45 116 274932 30496 42315791
Cellulitis 19.74 10.45 529 274519 61056 42285231
Language disorder 19.70 10.45 47 275001 2428 42343859
Electrocardiogram QT prolonged 19.63 10.45 206 274842 47739 42298548
Trisomy 18 19.59 10.45 26 275022 839 42345448
Tendonitis 19.57 10.45 120 274928 9774 42336513
Radiation pneumonitis 19.48 10.45 52 274996 2881 42343406
Maternal exposure before pregnancy 19.38 10.45 29 275019 1048 42345239
Hypotension 19.37 10.45 1416 273632 256215 42090072
Foetal disorder 19.34 10.45 29 275019 1050 42345237
Potentiating drug interaction 18.93 10.45 9 275039 6459 42339828
Hyperhidrosis 18.92 10.45 442 274606 90070 42256217
Dyspraxia 18.80 10.45 19 275029 454 42345833
Vasculitis 18.56 10.45 191 274857 18203 42328084
Infective pulmonary exacerbation of cystic fibrosis 18.51 10.45 14 275034 7804 42338483
Decreased appetite 18.39 10.45 1466 273582 191671 42154616
Haemodynamic instability 18.39 10.45 33 275015 12524 42333763
Nephropathy toxic 18.34 10.45 52 274996 16786 42329501
Unresponsive to stimuli 18.25 10.45 123 274925 31280 42315007
Exposure via skin contact 18.15 10.45 5 275043 5033 42341254
Blood pressure increased 18.15 10.45 818 274230 101110 42245177
Hyperbilirubinaemia neonatal 18.09 10.45 25 275023 839 42345448
Selective eating disorder 18.00 10.45 37 275011 1727 42344560
Hepatitis 17.90 10.45 103 274945 27197 42319090
Acute graft versus host disease 17.85 10.45 16 275032 8199 42338088
Temperature regulation disorder 17.78 10.45 29 275019 1130 42345157
Ankylosing spondylitis 17.55 10.45 91 274957 6965 42339322
Blood albumin decreased 17.53 10.45 164 274884 15238 42331049
Tinea pedis 17.52 10.45 40 275008 2008 42344279
Anal fistula 17.49 10.45 83 274965 6130 42340157
Astigmatism 17.38 10.45 31 275017 1300 42344987
Upper respiratory tract inflammation 17.30 10.45 38 275010 1858 42344429
Joint range of motion decreased 17.25 10.45 97 274951 7656 42338631
Thymus disorder 17.24 10.45 14 275034 249 42346038
Blood lactate dehydrogenase increased 17.24 10.45 250 274798 25831 42320456
Arthrodesis 17.23 10.45 20 275028 561 42345726
Arthritis infective 17.21 10.45 62 274986 4044 42342243
Radiation inflammation 17.14 10.45 27 275021 1021 42345266
Motor developmental delay 17.08 10.45 22 275026 689 42345598
Knee deformity 17.00 10.45 23 275025 756 42345531
Crohn's disease 16.97 10.45 50 274998 2934 42343353
Irritability 16.94 10.45 109 274939 28019 42318268
Somnolence 16.93 10.45 741 274307 140364 42205923
Nasal disorder 16.92 10.45 39 275009 1970 42344317
Dyslexia 16.90 10.45 16 275032 352 42345935
Cerebral infarction 16.89 10.45 289 274759 30880 42315407
Disease recurrence 16.87 10.45 117 274931 29561 42316726
Mydriasis 16.86 10.45 19 275029 8751 42337536
Burns second degree 16.84 10.45 81 274967 6015 42340272
Endophthalmitis 16.74 10.45 4 275044 4429 42341858
Antineutrophil cytoplasmic antibody positive 16.69 10.45 64 274984 4301 42341986
Cleft lip and palate 16.63 10.45 25 275023 907 42345380
Ankyloglossia congenital 16.53 10.45 16 275032 362 42345925
Limb reduction defect 16.33 10.45 15 275033 317 42345970
Cardiogenic shock 16.32 10.45 149 274899 35491 42310796
Hepatic failure 16.30 10.45 162 274886 37938 42308349
Congenital foot malformation 16.30 10.45 17 275031 422 42345865
Vision blurred 16.26 10.45 246 274802 53453 42292834
Hepatocellular injury 16.25 10.45 88 274960 23590 42322697
Lower respiratory tract infection 16.22 10.45 364 274684 40842 42305445
Bulbospinal muscular atrophy congenital 16.19 10.45 7 275041 34 42346253
Hypotonia neonatal 16.18 10.45 32 275016 1452 42344835
Skin cancer 16.17 10.45 128 274920 11334 42334953
Gingival pain 16.16 10.45 102 274946 8392 42337895
Abdominal discomfort 16.14 10.45 616 274432 74639 42271648
Obsessive-compulsive disorder 16.06 10.45 12 275036 6731 42339556
Blood test abnormal 16.00 10.45 140 274908 12766 42333521
Transient aphasia 15.96 10.45 20 275028 609 42345678
Systemic lupus erythematosus 15.94 10.45 109 274939 9215 42337072
Lip swelling 15.90 10.45 66 274982 18987 42327300
Disinhibition 15.76 10.45 3 275045 3892 42342395
Pneumonia aspiration 15.72 10.45 429 274619 49649 42296638
Fall 15.57 10.45 1735 273313 232785 42113502
Paranoia 15.51 10.45 43 275005 13983 42332304
Central nervous system mass 15.43 10.45 23 275025 828 42345459
Progressive multifocal leukoencephalopathy 15.43 10.45 32 275016 11504 42334783
Vitamin D deficiency 15.40 10.45 97 274951 7976 42338311
Localised infection 15.39 10.45 200 274848 20173 42326114
Hydrocele 15.38 10.45 44 275004 2539 42343748
Wall motion score index abnormal 15.35 10.45 23 275025 832 42345455
Oxygen saturation decreased 15.21 10.45 535 274513 64152 42282135
Dissociation 15.21 10.45 3 275045 3795 42342492
Spina bifida 14.99 10.45 16 275032 408 42345879
Tuberculosis 14.92 10.45 114 274934 9985 42336302
Synovial cyst 14.90 10.45 44 275004 2585 42343702
Product quality issue 14.89 10.45 62 274986 17820 42328467
Extrapyramidal disorder 14.88 10.45 55 274993 16357 42329930
Erectile dysfunction 14.77 10.45 97 274951 24816 42321471
Intellectual disability 14.70 10.45 36 275012 1891 42344396
Cardiac septal defect 14.70 10.45 24 275024 936 42345351
Hypertransaminasaemia 14.67 10.45 23 275025 9204 42337083
Post procedural infection 14.66 10.45 75 274973 5710 42340577
Lymphangiosis carcinomatosa 14.64 10.45 25 275023 1012 42345275
Confusional state 14.62 10.45 909 274139 166688 42179599
Medical device implantation 14.58 10.45 19 275029 602 42345685
Cleft lip 14.57 10.45 14 275034 314 42345973
Ear disorder 14.54 10.45 37 275011 1991 42344296
Peritonitis 14.53 10.45 184 274864 18449 42327838
Multiple congenital abnormalities 14.52 10.45 18 275030 542 42345745
Airway remodelling 14.46 10.45 23 275025 877 42345410
Thrombotic microangiopathy 14.43 10.45 48 275000 14734 42331553
Posterior reversible encephalopathy syndrome 14.41 10.45 39 275009 12782 42333505
Congenital bladder anomaly 14.38 10.45 13 275035 269 42346018
Lacrimal disorder 14.35 10.45 14 275034 320 42345967
Miosis 14.30 10.45 42 275006 13404 42332883
Transfusion-related circulatory overload 14.26 10.45 21 275027 748 42345539
Mental impairment 14.20 10.45 37 275011 12280 42334007
Congenital anomaly 14.19 10.45 31 275017 1510 42344777
Spinal disorder 14.16 10.45 63 274985 4528 42341759
Weight decrease neonatal 14.11 10.45 14 275034 327 42345960
Dysstasia 14.09 10.45 146 274902 13940 42332347
Otitis media 14.09 10.45 54 274994 3629 42342658
Nocardiosis 14.04 10.45 8 275040 5182 42341105
Pectus excavatum 14.03 10.45 12 275036 230 42346057
Chronic graft versus host disease 13.99 10.45 11 275037 6014 42340273
Hepatitis B reactivation 13.98 10.45 6 275042 4572 42341715
Renal aplasia 13.97 10.45 21 275027 762 42345525
Red blood cell sedimentation rate 13.90 10.45 25 275023 1055 42345232
Bronchospasm 13.88 10.45 40 275008 12845 42333442
Malignant melanoma 13.83 10.45 106 274942 9294 42336993
Rash maculo-papular 13.82 10.45 165 274883 37338 42308949
Anaemia 13.81 10.45 2036 273012 278242 42068045
Carcinoid tumour of the small bowel 13.70 10.45 15 275033 394 42345893
Pleural effusion 13.61 10.45 762 274286 96404 42249883
Oral mucosal discolouration 13.58 10.45 6 275042 31 42346256
Euglycaemic diabetic ketoacidosis 13.57 10.45 10 275038 5650 42340637
Hyperthermia 13.57 10.45 39 275009 12535 42333752
Mania 13.49 10.45 30 275018 10517 42335770
Gastrointestinal infection 13.47 10.45 82 274966 6661 42339626
Haemangioma congenital 13.45 10.45 17 275031 522 42345765
Bronchopulmonary aspergillosis 13.45 10.45 72 274976 19357 42326930
Fistula discharge 13.44 10.45 25 275023 1083 42345204
Hallucination 13.40 10.45 276 274772 57231 42289056
Inguinal hernia 13.39 10.45 101 274947 8811 42337476
Psychomotor hyperactivity 13.34 10.45 32 275016 10926 42335361
Renal injury 13.32 10.45 38 275010 12242 42334045
Musculoskeletal pain 13.27 10.45 295 274753 33045 42313242
Contusion 13.27 10.45 360 274688 41625 42304662
Visual impairment 13.23 10.45 197 274851 42916 42303371
Parosmia 13.20 10.45 90 274958 7601 42338686
Syncope 13.19 10.45 516 274532 98890 42247397
Cystitis bacterial 13.12 10.45 11 275037 205 42346082
Cholangitis 13.11 10.45 116 274932 10611 42335676
Influenza 13.11 10.45 508 274540 61667 42284620
Atopy 13.11 10.45 23 275025 952 42345335
Generalised tonic-clonic seizure 13.10 10.45 108 274940 26271 42320016
Hypertelorism 13.09 10.45 18 275030 601 42345686
Ventricular tachycardia 13.00 10.45 128 274920 30032 42316255
Skin injury 12.93 10.45 42 275006 2599 42343688
Frequent bowel movements 12.91 10.45 202 274846 21205 42325082
Candida infection 12.88 10.45 84 274964 21526 42324761
Anaemia vitamin B12 deficiency 12.87 10.45 17 275031 546 42345741
Blood parathyroid hormone decreased 12.86 10.45 31 275017 1612 42344675
Fracture 12.84 10.45 93 274955 8010 42338277
Therapy non-responder 12.76 10.45 255 274793 53104 42293183
Cholestasis 12.76 10.45 143 274905 32736 42313551
Umbilical hernia 12.69 10.45 69 274979 5378 42340909
Arnold-Chiari malformation 12.60 10.45 14 275034 374 42345913
Anaphylactic reaction 12.54 10.45 197 274851 42546 42303741
Neck mass 12.49 10.45 33 275015 1817 42344470
Ileus 12.47 10.45 183 274865 18956 42327331
Joint stiffness 12.46 10.45 128 274920 12194 42334093
Joint ankylosis 12.45 10.45 31 275017 1646 42344641
Granuloma skin 12.41 10.45 25 275023 1150 42345137
Oesophageal fibrosis 12.40 10.45 10 275038 176 42346111
Blister infected 12.25 10.45 16 275032 508 42345779
Aspartate aminotransferase increased 12.19 10.45 612 274436 76551 42269736
Psychiatric decompensation 12.17 10.45 6 275042 4216 42342071
Tooth malformation 12.17 10.45 10 275038 181 42346106
Abortion spontaneous 12.14 10.45 14 275034 390 42345897
Arthritis bacterial 12.13 10.45 72 274976 5796 42340491
Septic arthritis staphylococcal 12.13 10.45 16 275032 513 42345774
Cholelithiasis 12.13 10.45 215 274833 23131 42323156
Depression suicidal 12.11 10.45 3 275045 3242 42343045
Hiccups 12.10 10.45 126 274922 12045 42334242
Eosinophil percentage increased 12.09 10.45 17 275031 580 42345707
Haemangioma 12 10.45 34 275014 1951 42344336
Hypertriglyceridaemia 11.99 10.45 30 275018 10096 42336191
Mechanical ileus 11.97 10.45 16 275032 520 42345767
Enteritis infectious 11.95 10.45 30 275018 1601 42344686
Eosinophilic myocarditis 11.95 10.45 27 275021 1346 42344941
Myoclonus 11.95 10.45 63 274985 17002 42329285
Pleural fibrosis 11.93 10.45 27 275021 1347 42344940
Hernia pain 11.93 10.45 12 275036 285 42346002
Spinal compression fracture 11.93 10.45 86 274962 7397 42338890
Electrocardiogram QRS complex prolonged 11.88 10.45 12 275036 5811 42340476
Blood magnesium decreased 11.86 10.45 88 274960 7638 42338649
Diabetic ketoacidosis 11.83 10.45 90 274958 22277 42324010
Cancer pain 11.81 10.45 50 274998 3517 42342770
Anti-cyclic citrullinated peptide antibody positive 11.80 10.45 33 275015 1879 42344408
Osteomyelitis 11.77 10.45 174 274874 18049 42328238
Disability assessment scale score increased 11.75 10.45 14 275034 404 42345883
Hepatitis cholestatic 11.72 10.45 29 275019 9795 42336492
Haematoma 11.63 10.45 120 274928 27903 42318384
Klebsiella infection 11.62 10.45 36 275012 11296 42334991
Spondyloarthropathy 11.57 10.45 21 275027 893 42345394
Polydactyly 11.56 10.45 25 275023 1209 42345078
Vascular insufficiency 11.56 10.45 13 275035 352 42345935
Pulmonary pain 11.53 10.45 29 275019 1549 42344738
Respiratory failure 11.51 10.45 693 274355 127439 42218848
Colon cancer 11.48 10.45 104 274944 9577 42336710
Neutropenia neonatal 11.47 10.45 21 275027 899 42345388
Obstructive airways disorder 11.47 10.45 224 274824 24535 42321752
Diverticular perforation 11.47 10.45 51 274997 3665 42342622
Blood insulin increased 11.45 10.45 13 275035 356 42345931
Meningeal disorder 11.42 10.45 13 275035 357 42345930
Gross motor delay 11.39 10.45 13 275035 358 42345929
Skin abrasion 11.37 10.45 91 274957 8084 42338203
Hepatic steatosis 11.31 10.45 198 274850 21250 42325037
Strongyloidiasis 11.30 10.45 4 275044 3427 42342860
Palmar-plantar erythrodysaesthesia syndrome 11.28 10.45 82 274966 20500 42325787
Tardive dyskinesia 11.26 10.45 17 275031 6907 42339380
Microcephaly 11.24 10.45 21 275027 913 42345374
Autoscopy 11.22 10.45 11 275037 253 42346034
Back disorder 11.20 10.45 85 274963 7429 42338858
Hepatotoxicity 11.19 10.45 106 274942 25061 42321226
Immunodeficiency 11.17 10.45 83 274965 7207 42339080
Shock 11.17 10.45 127 274921 28994 42317293
Blindness 11.17 10.45 69 274979 17909 42328378
Congestive cardiomyopathy 11.15 10.45 25 275023 8739 42337548
Steroid dependence 11.15 10.45 78 274970 6644 42339643
Gangrene neonatal 11.14 10.45 10 275038 205 42346082
Fear 11.12 10.45 35 275013 10930 42335357
Hepatitis E antibody positive 11.12 10.45 11 275037 256 42346031
Apparent death 11.10 10.45 5 275043 3703 42342584
Diverticulum 11.07 10.45 85 274963 7456 42338831
Low set ears 11.07 10.45 15 275033 494 42345793
Iron overload 11.00 10.45 28 275020 1507 42344780
Panniculitis 10.96 10.45 35 275013 2146 42344141
Complications of transplanted kidney 10.94 10.45 11 275037 5339 42340948
Paraesthesia 10.94 10.45 376 274672 73083 42273204
Hallucination, visual 10.92 10.45 85 274963 20935 42325352
Stress ulcer 10.88 10.45 11 275037 263 42346024
Maternal exposure timing unspecified 10.86 10.45 13 275035 377 42345910
Second primary malignancy 10.86 10.45 29 275019 9546 42336741
Intervertebral disc degeneration 10.80 10.45 83 274965 7284 42339003
Lung cancer metastatic 10.79 10.45 43 275005 2943 42343344
Bone cyst 10.69 10.45 29 275019 1622 42344665
Peripheral artery thrombosis 10.69 10.45 40 275008 2657 42343630
Abdominal adhesions 10.69 10.45 30 275018 1712 42344575
Dry skin 10.68 10.45 234 274814 48104 42298183
Venoocclusive disease 10.64 10.45 6 275042 3909 42342378
Liver injury 10.63 10.45 76 274972 19072 42327215
Photosensitivity reaction 10.60 10.45 44 275004 12658 42333629
Ocular hyperaemia 10.59 10.45 60 274988 15903 42330384
Methaemoglobinaemia 10.57 10.45 13 275035 5761 42340526
Glomerular filtration rate decreased 10.55 10.45 62 274986 16289 42329998
Pleuritic pain 10.52 10.45 80 274968 6997 42339290
Acute respiratory distress syndrome 10.52 10.45 134 274914 29974 42316313
Brain oedema 10.49 10.45 62 274986 16265 42330022
Hypoglycaemia 10.45 10.45 300 274748 59554 42286733

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Toxicity to various agents 1372.08 10.00 1136 897989 479419 109210755
Completed suicide 1265.61 10.00 222 898903 242159 109448015
Drug abuse 942.58 10.00 155 898970 177256 109512918
Systemic lupus erythematosus 892.39 10.00 4264 894861 250074 109440100
Arthropathy 859.74 10.00 4608 894517 282914 109407260
Synovitis 827.12 10.00 4404 894721 269688 109420486
Pemphigus 820.98 10.00 3690 895435 210880 109479294
Hand deformity 801.30 10.00 3711 895414 214795 109475379
Glossodynia 734.93 10.00 3661 895464 218343 109471831
Drug interaction 723.43 10.00 1900 897225 498283 109191891
Joint swelling 715.80 10.00 6092 893033 436753 109253421
Anti-cyclic citrullinated peptide antibody positive 635.09 10.00 3047 896078 178937 109511237
Wound 627.18 10.00 3647 895478 230790 109459384
Rheumatoid arthritis 613.21 10.00 4355 894770 295258 109394916
Pericarditis 601.37 10.00 3432 895693 215682 109474492
Maternal exposure during pregnancy 559.35 10.00 3769 895356 251114 109439060
Intentional overdose 558.03 10.00 190 898935 132311 109557863
Infusion related reaction 553.44 10.00 5123 894002 376039 109314135
Duodenal ulcer perforation 543.03 10.00 2866 896259 174834 109515340
Abdominal discomfort 521.13 10.00 5191 893934 388667 109301507
Helicobacter infection 507.03 10.00 2861 896264 179016 109511158
Arthralgia 493.77 10.00 8989 890136 770643 108919531
Swelling 489.94 10.00 4679 894446 346362 109343812
Alopecia 467.82 10.00 4777 894348 359976 109330198
Psoriatic arthropathy 442.04 10.00 2927 896198 193834 109496340
Therapeutic product effect decreased 436.12 10.00 3439 895686 240877 109449297
Rheumatoid factor positive 424.86 10.00 2156 896969 129484 109560690
Death 415.36 10.00 3658 895467 695211 108994963
Discomfort 391.87 10.00 3038 896087 211669 109478505
Acute kidney injury 376.56 10.00 3328 895797 632102 109058072
Contraindicated product administered 369.17 10.00 3355 895770 244912 109445262
Musculoskeletal stiffness 357.27 10.00 3662 895463 276160 109414014
Impaired healing 354.28 10.00 2775 896350 193942 109496232
Hepatic enzyme increased 335.89 10.00 4038 895087 316854 109373320
Pain 334.70 10.00 10141 888984 944814 108745360
Suicide attempt 332.69 10.00 215 898910 103179 109586995
Folliculitis 311.84 10.00 2383 896742 165270 109524904
Nasopharyngitis 306.59 10.00 4704 894421 389657 109300517
Overdose 304.38 10.00 933 898192 232861 109457313
C-reactive protein abnormal 289.74 10.00 1927 897198 127768 109562406
Irritable bowel syndrome 279.00 10.00 2286 896839 161929 109528245
Blister 278.48 10.00 2951 896174 224425 109465749
Muscle injury 278.03 10.00 2030 897095 138777 109551397
Cardiac arrest 272.21 10.00 763 898362 195990 109494184
Sedation 268.28 10.00 115 899010 69568 109620606
Lactic acidosis 267.30 10.00 217 898908 92594 109597580
Coma 255.98 10.00 350 898775 117519 109572655
Rheumatic fever 255.21 10.00 1790 897335 120789 109569385
Sleep disorder due to general medical condition, insomnia type 254.57 10.00 1600 897525 104043 109586131
Fibromyalgia 251.08 10.00 2304 896821 168605 109521569
Exposure during pregnancy 246.45 10.00 2258 896867 165166 109525008
Drug ineffective for unapproved indication 244.54 10.00 285 898840 102553 109587621
Stomatitis 244.24 10.00 3310 895815 266932 109423242
Drug resistance 242.29 10.00 78 899047 56296 109633878
Drug intolerance 238.18 10.00 4634 894491 401878 109288296
Lower respiratory tract infection 236.93 10.00 3019 896106 240087 109450087
Off label use 230.70 10.00 9917 889208 1490268 108199906
Disease progression 230.40 10.00 1109 898016 242925 109447249
Drug reaction with eosinophilia and systemic symptoms 228.97 10.00 198 898927 81897 109608277
Hypotension 208.64 10.00 3000 896125 520849 109169325
Osteoarthritis 208.25 10.00 2337 896788 180286 109509888
Bradycardia 205.67 10.00 616 898509 154901 109535273
Angioedema 204.46 10.00 302 898823 98198 109591976
Ill-defined disorder 204.45 10.00 2062 897063 154791 109535383
Neutropenia 202.23 10.00 2007 897118 372613 109317561
Serotonin syndrome 201.47 10.00 115 899010 59038 109631136
Peripheral swelling 200.16 10.00 4494 894631 399540 109290634
Swollen joint count increased 199.64 10.00 1264 897861 82397 109607777
Sinusitis 199.51 10.00 3456 895669 293232 109396942
Type 2 diabetes mellitus 192.19 10.00 2246 896879 174986 109515188
Sopor 191.65 10.00 33 899092 36513 109653661
Sickle cell anaemia with crisis 190.09 10.00 305 898820 9240 109680934
Myelosuppression 188.35 10.00 297 898828 94043 109596131
Hyperhidrosis 186.93 10.00 834 898291 186464 109503710
Inflammation 182.45 10.00 2386 896739 190852 109499322
Agitation 177.49 10.00 411 898714 112640 109577534
Red blood cell sedimentation rate abnormal 177.14 10.00 519 898606 23990 109666184
Rhabdomyolysis 177.00 10.00 453 898672 119948 109570226
Renal failure 176.29 10.00 1098 898027 225476 109464698
Hypersensitivity 176.10 10.00 4415 894710 399583 109290591
Weight increased 172.98 10.00 4552 894573 415092 109275082
Contusion 172.54 10.00 2761 896364 230600 109459574
C-reactive protein increased 169.73 10.00 2601 896524 215318 109474856
Product use in unapproved indication 164.67 10.00 2601 896524 444776 109245398
Multiple organ dysfunction syndrome 161.54 10.00 659 898466 151051 109539123
Electrocardiogram QT prolonged 157.07 10.00 414 898711 108546 109581628
Depressed level of consciousness 155.55 10.00 435 898690 111843 109578331
Drug dependence 155.53 10.00 108 899017 49912 109640262
Febrile neutropenia 153.90 10.00 1739 897386 315028 109375146
Facet joint syndrome 153.81 10.00 1328 897797 95500 109594674
Intentional product misuse 153.28 10.00 559 898566 132345 109557829
Knee arthroplasty 152.31 10.00 977 898148 63971 109626203
Arthritis 149.80 10.00 2049 897076 165537 109524637
Respiratory arrest 148.04 10.00 153 898972 58146 109632028
Metabolic acidosis 146.06 10.00 376 898749 99368 109590806
Somnolence 145.26 10.00 1631 897494 295818 109394356
Joint range of motion decreased 144.77 10.00 1572 897553 120260 109569914
Blood pressure systolic abnormal 144.43 10.00 488 898637 24362 109665812
Pregnancy 143.93 10.00 806 898319 50261 109639913
Blood cholesterol increased 142.91 10.00 2203 896922 182582 109507592
Poisoning 142.65 10.00 31 899094 29074 109661100
Grip strength decreased 142.02 10.00 1127 897998 79047 109611127
Treatment failure 141.40 10.00 3097 896028 274137 109416037
Intentional self-injury 137.47 10.00 66 899059 37363 109652811
Constipation 137.43 10.00 2063 897062 355723 109334451
Tachycardia 137.00 10.00 1180 897945 225465 109464709
Blood pressure diastolic abnormal 136.22 10.00 491 898634 25324 109664850
Hip arthroplasty 132.98 10.00 843 898282 54970 109635204
Blood pressure systolic increased 130.13 10.00 1135 897990 81856 109608318
Blood pressure fluctuation 129.37 10.00 1046 898079 73778 109616396
Pulmonary fibrosis 128.41 10.00 1332 897793 100710 109589464
Red blood cell sedimentation rate increased 123.35 10.00 1072 898053 77230 109612944
Drug use disorder 121.77 10.00 6 899119 18068 109672106
Lip dry 121.04 10.00 1296 897829 98787 109591387
Respiratory failure 120.58 10.00 1143 897982 214189 109475985
Infection 119.75 10.00 3822 895303 358378 109331796
Cognitive disorder 118.30 10.00 343 898782 87168 109603006
Syncope 116.45 10.00 1068 898057 201468 109488706
Live birth 114.04 10.00 960 898165 68524 109621650
Product use issue 113.42 10.00 3328 895797 308367 109381807
Hyponatraemia 111.61 10.00 1180 897945 216473 109473701
Hepatocellular injury 110.31 10.00 150 898975 50492 109639682
Suicidal ideation 109.04 10.00 394 898731 93543 109596631
Abortion spontaneous 107.40 10.00 557 898568 33725 109656449
No adverse event 106.08 10.00 281 898844 73558 109616616
Neurotoxicity 105.78 10.00 112 899013 42095 109648079
Hypermagnesaemia 105.73 10.00 95 899030 1528 109688646
Respiratory depression 105.05 10.00 65 899060 31936 109658238
Intentional product use issue 104.60 10.00 2698 896427 245208 109444966
Disturbance in attention 104.21 10.00 217 898908 61778 109628396
Myalgia 103.62 10.00 1232 897893 221149 109469025
Hypoglycaemia 101.90 10.00 541 898584 115563 109574611
Musculoskeletal pain 101.19 10.00 2069 897056 180954 109509220
Thrombocytopenia 101.02 10.00 2115 897010 346770 109343404
Injury 100.68 10.00 2012 897113 175253 109514921
Joint effusion 100.61 10.00 386 898739 20519 109669655
Mobility decreased 99.90 10.00 2583 896542 234839 109455335
Cardio-respiratory arrest 99.86 10.00 543 898582 115293 109574881
Bursitis 97.42 10.00 1541 897584 128377 109561797
Deep vein thrombosis postoperative 97.21 10.00 819 898306 58472 109631702
Hepatic failure 96.93 10.00 264 898861 68475 109621699
Sedation complication 95.59 10.00 22 899103 19833 109670341
Chest discomfort 95.54 10.00 927 898198 172921 109517253
Cholestasis 95.38 10.00 242 898883 64276 109625898
Anaphylactic shock 94.83 10.00 171 898954 51375 109638799
Mydriasis 94.60 10.00 31 899094 22126 109668048
Disability assessment scale score increased 92.75 10.00 142 898983 4128 109686046
Vision blurred 92.36 10.00 641 898484 128381 109561793
Drug withdrawal syndrome 92.03 10.00 104 899021 37950 109652224
Neuropathy peripheral 91.88 10.00 972 898153 178305 109511869
Myocardial infarction 91.47 10.00 1059 898066 191024 109499150
Cytomegalovirus infection 91.15 10.00 191 898934 54253 109635921
Acute hepatic failure 90.03 10.00 98 899027 36370 109653804
Psychotic disorder 89.28 10.00 174 898951 50763 109639411
Therapy partial responder 88.85 10.00 102 899023 36959 109653215
Wound infection 88.45 10.00 1185 897940 95280 109594894
Tremor 88.32 10.00 1136 897989 201096 109489078
Neoplasm progression 88.17 10.00 252 898873 64343 109625831
Seizure 86.72 10.00 1270 897855 219915 109470259
Breast cancer stage III 85.43 10.00 1002 898123 78115 109612059
Obesity 84.79 10.00 1344 897781 112007 109578167
Pathogen resistance 84.25 10.00 20 899105 17652 109672522
Sciatica 83.87 10.00 1133 897992 91266 109598908
Suspected suicide 83.60 10.00 12 899113 15187 109674987
Accidental exposure to product 83.25 10.00 176 898949 49832 109640342
Peripheral venous disease 81.59 10.00 1044 898081 83073 109607101
Nodule 81.57 10.00 499 898626 32132 109658042
Pain in extremity 81.39 10.00 4788 894337 482330 109207844
Blood pressure diastolic decreased 81.19 10.00 535 898590 35350 109654824
Gastrointestinal disorder 79.35 10.00 2551 896574 239401 109450773
Aspergillus infection 78.73 10.00 56 899069 25560 109664614
Exposure to toxic agent 78.62 10.00 7 899118 12851 109677323
Autoimmune disorder 77.80 10.00 845 898280 64638 109625536
Ventricular tachycardia 77.53 10.00 183 898942 49826 109640348
Enthesopathy 76.94 10.00 250 898875 12228 109677946
Withdrawal syndrome 76.72 10.00 85 899040 31295 109658879
Leukopenia 76.53 10.00 806 898319 147985 109542189
Condition aggravated 76.47 10.00 6952 892173 727884 108962290
Rheumatoid nodule 75.96 10.00 347 898778 19949 109670225
Aggression 75.78 10.00 238 898887 58972 109631202
Lung disorder 75.77 10.00 1959 897166 178088 109512086
Substance abuse 75.63 10.00 7 899118 12456 109677718
Loss of personal independence in daily activities 74.56 10.00 1670 897455 148350 109541824
Anaphylactic reaction 74.54 10.00 583 898542 113717 109576457
Dysarthria 74.35 10.00 391 898734 83730 109606444
Liver injury 74.32 10.00 1673 897452 148740 109541434
Temperature regulation disorder 73.24 10.00 9 899116 12817 109677357
Balance disorder 72.58 10.00 602 898523 115958 109574216
Shock 72.45 10.00 210 898915 53378 109636796
Foot deformity 72.37 10.00 656 898469 47824 109642350
Bone erosion 72.07 10.00 633 898492 45738 109644436
Haematotoxicity 71.76 10.00 41 899084 21041 109669133
Orthostatic hypotension 71.61 10.00 286 898839 65963 109624211
Thrombotic microangiopathy 71.22 10.00 79 899046 29070 109661104
Wrong technique in product usage process 71.20 10.00 417 898708 86931 109603243
Disease recurrence 71.17 10.00 254 898871 60530 109629644
Road traffic accident 70.99 10.00 1248 897877 106150 109584024
Cytokine release syndrome 70.75 10.00 312 898813 69994 109620180
Dry skin 70.72 10.00 548 898577 107105 109583069
Unresponsive to stimuli 70.48 10.00 273 898852 63517 109626657
Liver disorder 70.24 10.00 1582 897543 140661 109549513
Polyarthritis 70.07 10.00 323 898802 18640 109671534
Rash 69.10 10.00 7654 891471 813310 108876864
Cardiac failure 68.86 10.00 1091 898034 186535 109503639
Respiratory distress 68.49 10.00 307 898818 68567 109621607
Encephalopathy 68.19 10.00 383 898742 80672 109609502
Neuroleptic malignant syndrome 68.18 10.00 107 899018 33952 109656222
Post transplant lymphoproliferative disorder 68.16 10.00 21 899104 15592 109674582
Heart rate decreased 67.57 10.00 996 898129 81760 109608414
Joint stiffness 67.10 10.00 839 898286 66404 109623770
Cardiogenic shock 66.86 10.00 240 898885 57098 109633076
Myoclonus 66.70 10.00 103 899022 32895 109657279
BK virus infection 66.21 10.00 13 899112 13093 109677081
Juvenile idiopathic arthritis 66.04 10.00 149 898976 5858 109684316
Immune reconstitution inflammatory syndrome 65.35 10.00 25 899100 16201 109673973
Creatinine renal clearance decreased 65.34 10.00 49 899076 21766 109668408
Disorientation 65.00 10.00 324 898801 70347 109619827
Ejection fraction decreased 64.65 10.00 148 898977 40732 109649442
Extrapyramidal disorder 64.40 10.00 84 899041 28783 109661391
Personality disorder 64.30 10.00 13 899112 12824 109677350
Skin exfoliation 63.94 10.00 433 898692 87218 109602956
Joint destruction 63.68 10.00 215 898910 10728 109679446
Osteoporosis 63.54 10.00 1029 898096 86123 109604051
Posterior reversible encephalopathy syndrome 63.49 10.00 111 899014 33750 109656424
Cytomegalovirus infection reactivation 63.35 10.00 35 899090 18298 109671876
Dyspnoea 63.06 10.00 7960 891165 1098912 108591262
Eosinophilia 62.70 10.00 250 898875 57686 109632488
Miosis 62.54 10.00 52 899073 21931 109668243
Injection site reaction 62.48 10.00 1045 898080 88025 109602149
Hyperglycaemia 62.25 10.00 420 898705 84670 109605504
Adverse event 62.09 10.00 1236 897889 107573 109582601
Venoocclusive liver disease 61.96 10.00 23 899102 15184 109674990
Nausea 61.89 10.00 8958 890167 1226732 108463442
Rebound effect 60.99 10.00 22 899103 14784 109675390
Acute graft versus host disease 60.58 10.00 15 899110 12866 109677308
Bronchospasm 60.53 10.00 95 899030 30144 109660030
Gait inability 60.37 10.00 1494 897631 134882 109555292
Neurologic neglect syndrome 59.84 10.00 4 899121 9294 109680880
Oedema 59.55 10.00 2177 896948 207799 109482375
Mucormycosis 59.38 10.00 8 899117 10620 109679554
Irritability 59.21 10.00 195 898930 47614 109642560
Toxic epidermal necrolysis 58.75 10.00 249 898876 56478 109633696
Hallucination 58.22 10.00 535 898590 100897 109589277
Dry mouth 57.91 10.00 2078 897047 197870 109492304
Rash erythematous 57.36 10.00 409 898716 81423 109608751
Akathisia 57.23 10.00 34 899091 17079 109673095
Adjustment disorder with depressed mood 57.18 10.00 577 898548 43306 109646868
Hepatotoxicity 56.98 10.00 293 898832 63107 109627067
Bronchopulmonary aspergillosis 56.81 10.00 97 899028 29766 109660408
Device difficult to use 56.63 10.00 42 899083 18763 109671411
Blood pressure diastolic increased 56.46 10.00 302 898823 18505 109671669
Caesarean section 56.07 10.00 242 898883 13575 109676599
Flushing 56.05 10.00 562 898563 104174 109586000
Interstitial lung disease 55.72 10.00 1506 897619 137828 109552346
Lower limb fracture 55.44 10.00 891 898234 74457 109615717
Psychomotor hyperactivity 55.21 10.00 50 899075 20227 109669947
Hypothermia 55.20 10.00 80 899045 26222 109663952
Aphasia 55.11 10.00 269 898856 58728 109631446
Hypoaesthesia 55.00 10.00 3102 896023 311121 109379053
Diabetic ketoacidosis 54.57 10.00 168 898957 41890 109648284
Muscle twitching 54.45 10.00 100 899025 29835 109660339
Hemiparesis 54.42 10.00 179 898946 43724 109646450
Status epilepticus 54.34 10.00 109 899016 31462 109658712
Hypercholesterolaemia 54.24 10.00 1039 898086 89798 109600376
Restlessness 54.02 10.00 254 898871 56005 109634169
Joint laxity 53.93 10.00 83 899042 2424 109687750
Dislocation of vertebra 53.71 10.00 568 898557 43153 109647021
Torsade de pointes 53.32 10.00 63 899062 22537 109667637
Dermatitis atopic 53.29 10.00 78 899047 25463 109664711
Cerebrovascular accident 53.00 10.00 1097 898028 180187 109509987
Speech disorder 52.84 10.00 289 898836 61280 109628894
Coagulopathy 52.67 10.00 164 898961 40747 109649427
Prescribed underdose 52.66 10.00 783 898342 64391 109625783
Tenosynovitis 52.00 10.00 266 898859 16017 109674157
C-reactive protein 51.87 10.00 423 898702 29908 109660266
Drug ineffective 51.85 10.00 11255 887870 1509285 108180889
Coordination abnormal 51.71 10.00 78 899047 25150 109665024
Polyomavirus-associated nephropathy 51.43 10.00 4 899121 8197 109681977
Adenovirus infection 51.32 10.00 13 899112 10981 109679193
Brain oedema 51.30 10.00 110 899015 30988 109659186
Body temperature decreased 51.22 10.00 492 898633 36443 109653731
Drug dose omission by device 51.20 10.00 27 899098 14489 109675685
Emotional distress 50.79 10.00 190 898935 44657 109645517
Acute respiratory distress syndrome 49.43 10.00 243 898882 52955 109637219
Tachypnoea 49.26 10.00 160 898965 39235 109650939
Femur fracture 49.25 10.00 566 898559 43903 109646271
General physical health deterioration 49.20 10.00 4056 895069 421239 109268935
Multiple-drug resistance 49.12 10.00 23 899102 13212 109676962
Pancreatitis acute 48.99 10.00 288 898837 59986 109630188
Second primary malignancy 48.67 10.00 45 899080 18023 109672151
Exposure via skin contact 48.56 10.00 23 899102 13124 109677050
Gestational diabetes 48.25 10.00 151 898974 7238 109682936
Psoriasis 48.23 10.00 1485 897640 138508 109551666
Carotid artery thrombosis 47.78 10.00 10 899115 9628 109680546
Fracture 47.53 10.00 355 898770 24433 109665741
Basal cell carcinoma 47.40 10.00 570 898555 44700 109645474
Drug level increased 47.27 10.00 213 898912 47506 109642668
Fatigue 47.10 10.00 10861 888264 1205097 108485077
Paradoxical drug reaction 47.02 10.00 11 899114 9806 109680368
Unintentional medical device removal 46.91 10.00 8 899117 8915 109681259
Cardiotoxicity 46.72 10.00 41 899084 16840 109673334
Device expulsion 46.33 10.00 115 899010 30776 109659398
COVID-19 46.30 10.00 1579 897546 243481 109446693
Arrhythmia 46.24 10.00 353 898772 69222 109620952
Renal impairment 46.17 10.00 1172 897953 187273 109502901
Hemiplegia 46.15 10.00 71 899054 22711 109667463
Palpitations 46.08 10.00 965 898160 158247 109531927
Hyperkalaemia 45.76 10.00 802 898323 134994 109555180
Atrial fibrillation 45.43 10.00 1471 897654 228171 109462003
Neuritis 45.40 10.00 148 898977 7251 109682923
Sepsis 45.37 10.00 2186 896939 325160 109365014
Agranulocytosis 45.09 10.00 305 898820 61455 109628719
Dystonia 44.49 10.00 89 899036 25716 109664458
Acute generalised exanthematous pustulosis 44.38 10.00 67 899058 21597 109668577
Ventricular fibrillation 44.24 10.00 179 898946 41134 109649040
Skin haemorrhage 44.22 10.00 84 899041 24743 109665431
Sleep disorder 44.21 10.00 2007 897118 196637 109493537
Bradyphrenia 44.12 10.00 20 899105 11708 109678466
Dysphagia 43.86 10.00 933 898192 152667 109537507
Onychomycosis 43.84 10.00 493 898632 38038 109652136
Localised infection 43.75 10.00 539 898586 42509 109647665
Polyneuropathy 43.60 10.00 125 899000 31887 109658287
Depressed mood 43.56 10.00 302 898823 60507 109629667
Hyperthermia 43.37 10.00 66 899059 21206 109668968
Hepatic cirrhosis 43.32 10.00 782 898343 66844 109623330
Malignant neoplasm progression 43.21 10.00 1084 898041 173483 109516691
Abnormal behaviour 43.17 10.00 167 898958 38872 109651302
Laryngitis 43.10 10.00 531 898594 41880 109648294
Generalised tonic-clonic seizure 43 10.00 264 898861 54416 109635758
Haemodynamic instability 42.94 10.00 75 899050 22813 109667361
Onychomadesis 42.70 10.00 563 898562 45100 109645074
Palmar-plantar erythrodysaesthesia syndrome 42.53 10.00 180 898945 40845 109649329
Acute graft versus host disease in skin 42.50 10.00 17 899108 10723 109679451
Blood glucose increased 42.29 10.00 790 898335 131706 109558468
Ischaemic stroke 42.19 10.00 182 898943 41081 109649093
Lip swelling 41.76 10.00 241 898884 50426 109639748
Wheezing 41.09 10.00 2501 896624 252729 109437445
Coronary artery disease 40.76 10.00 379 898746 71311 109618863
Clostridium difficile colitis 40.66 10.00 200 898925 43578 109646596
Electrocardiogram QRS complex prolonged 40.63 10.00 28 899097 12993 109677181
Food allergy 40.57 10.00 62 899063 19886 109670288
Acute chest syndrome 40.25 10.00 66 899059 2037 109688137
Pulmonary vasculitis 40.06 10.00 131 898994 6429 109683745
Fear 39.98 10.00 80 899045 23113 109667061
Premature labour 39.83 10.00 164 898961 9008 109681166
Diffuse large B-cell lymphoma recurrent 39.70 10.00 3 899122 6296 109683878
Adjustment disorder 39.70 10.00 19 899106 10776 109679398
Muscle rigidity 39.64 10.00 85 899040 23946 109666228
Transplant rejection 39.61 10.00 88 899037 24479 109665695
Graft versus host disease in gastrointestinal tract 39.26 10.00 12 899113 8956 109681218
Anti-cyclic citrullinated peptide antibody 38.90 10.00 287 898838 19677 109670497
Haematoma 38.71 10.00 297 898828 58179 109631995
Night sweats 38.67 10.00 1392 897733 132591 109557583
X-ray abnormal 38.20 10.00 476 898649 37641 109652533
Rash maculo-papular 38.18 10.00 402 898723 73820 109616354
Motor dysfunction 38.08 10.00 89 899036 24317 109665857
Pulmonary oedema 38.04 10.00 582 898543 100077 109590097
Blood parathyroid hormone decreased 37.82 10.00 208 898917 12881 109677293
Candida infection 37.64 10.00 232 898893 47777 109642397
Haemophagocytic lymphohistiocytosis 37.53 10.00 131 898994 31428 109658746
Asthma-chronic obstructive pulmonary disease overlap syndrome 37.35 10.00 4 899121 6340 109683834
Red blood cell sedimentation rate 37.28 10.00 110 899015 5104 109685070
Product prescribing error 37.23 10.00 254 898871 51077 109639097
Wheelchair user 37.08 10.00 144 898981 7698 109682476
Hypokalaemia 36.97 10.00 1165 897960 181283 109508891
Lupus-like syndrome 36.93 10.00 500 898625 40292 109649882
Graft versus host disease 36.78 10.00 60 899065 18746 109671428
Febrile bone marrow aplasia 36.77 10.00 53 899072 17412 109672762
Mania 36.48 10.00 71 899054 20725 109669449
Blepharospasm 36.46 10.00 638 898487 54213 109635961
Potentiating drug interaction 36.38 10.00 25 899100 11618 109678556
Eye pruritus 36.37 10.00 140 898985 32635 109657539
Cardiac failure congestive 36.21 10.00 942 898183 150058 109540116
Cytopenia 35.82 10.00 125 899000 29991 109660183
Maternal exposure before pregnancy 35.66 10.00 135 898990 7130 109683044
Joint dislocation 35.58 10.00 430 898695 33760 109656414
Angina pectoris 35.56 10.00 329 898796 61966 109628208
Epstein-Barr virus infection 35.52 10.00 61 899064 18677 109671497
Pancytopenia 35.44 10.00 2063 897062 207550 109482624
Feeling abnormal 35.39 10.00 1159 897966 179552 109510622
Lethargy 35.37 10.00 541 898584 93035 109597139
Leukocytosis 35.35 10.00 274 898851 53554 109636620
Chills 35.29 10.00 1231 897894 189349 109500825
Alanine aminotransferase abnormal 35.24 10.00 160 898965 9174 109681000
Finger deformity 35.23 10.00 418 898707 32674 109657500
Dissociation 35.17 10.00 18 899107 9824 109680350
Retinitis 35.15 10.00 410 898715 31917 109658257
Loss of consciousness 34.98 10.00 1274 897851 195032 109495142
Cardiomyopathy 34.81 10.00 147 898978 33378 109656796
Melaena 34.72 10.00 374 898751 68383 109621791
Nocardiosis 34.66 10.00 9 899116 7477 109682697
Sexual dysfunction 34.59 10.00 13 899112 8517 109681657
Hypomania 34.55 10.00 20 899105 10190 109679984
Mental disorder 34.44 10.00 180 898945 38611 109651563
Granuloma skin 34.43 10.00 182 898943 11101 109679073
Haemorrhage 34.40 10.00 635 898490 106057 109584117
Exostosis 34.39 10.00 545 898580 45411 109644763
Respiratory acidosis 34.30 10.00 37 899088 13789 109676385
Chronic kidney disease 33.86 10.00 427 898698 75864 109614310
Proteinuria 33.71 10.00 189 898936 39829 109650345
Product dose omission issue 33.57 10.00 2209 896916 319573 109370601
Device use error 33.42 10.00 16 899109 9073 109681101
Skin toxicity 33.36 10.00 28 899097 11755 109678419
Haemorrhage intracranial 33.28 10.00 122 899003 28847 109661327
Labelled drug-drug interaction medication error 33.27 10.00 124 899001 29178 109660996
Neck deformity 33.18 10.00 57 899068 1829 109688345
Ear infection 32.96 10.00 704 898421 62028 109628146
Nephropathy toxic 32.71 10.00 114 899011 27364 109662810
Respiratory symptom 32.71 10.00 221 898904 14724 109675450
Sleep terror 32.48 10.00 7 899118 6603 109683571
Acute myocardial infarction 32.47 10.00 482 898643 83295 109606879
Anuria 32.46 10.00 96 899029 24245 109665929
Blood creatine phosphokinase increased 32.44 10.00 409 898716 72668 109617506
Mucosal inflammation 32.32 10.00 568 898557 95573 109594601
Hallucination, visual 32.31 10.00 189 898936 39416 109650758
Klebsiella infection 32.00 10.00 72 899053 19937 109670237
Infective pulmonary exacerbation of cystic fibrosis 31.92 10.00 44 899081 14727 109675447
Diarrhoea 31.92 10.00 8510 890615 1130995 108559179
Lupus vulgaris 31.78 10.00 418 898707 33465 109656709
Fluid retention 31.76 10.00 557 898568 93750 109596424
Maternal exposure timing unspecified 31.70 10.00 285 898840 20728 109669446
Hepatitis cholestatic 31.66 10.00 59 899066 17507 109672667
Pseudomonas infection 31.54 10.00 118 899007 27735 109662439
Hyperbilirubinaemia 31.53 10.00 135 898990 30536 109659638
Panniculitis 31.51 10.00 226 898899 15356 109674818
Blood creatinine increased 31.45 10.00 1192 897933 181697 109508477
Premature rupture of membranes 31.43 10.00 96 899029 4541 109685633
Sensory loss 31.31 10.00 81 899044 21376 109668798
Anxiety 31.25 10.00 2398 896727 342680 109347494
Multiple drug therapy 31.20 10.00 13 899112 8001 109682173
Asphyxia 31.06 10.00 42 899083 14173 109676001
Multiple sclerosis relapse 31.03 10.00 260 898865 49980 109640194
Atrial tachycardia 31.03 10.00 18 899107 9160 109681014
Bone pain 31.02 10.00 359 898766 64774 109625400
Blood calcium decreased 30.90 10.00 168 898957 35677 109654497
Sinus tachycardia 30.87 10.00 223 898902 44270 109645904
Sinus bradycardia 30.78 10.00 129 898996 29354 109660820
Progressive multifocal leukoencephalopathy 30.76 10.00 102 899023 24854 109665320
Vasoplegia syndrome 30.61 10.00 4 899121 5435 109684739
Diplopia 30.53 10.00 207 898918 41687 109648487
Latent tuberculosis 30.46 10.00 86 899039 3891 109686283
Diabetes insipidus 30.23 10.00 8 899117 6562 109683612
Hyperpyrexia 29.98 10.00 14 899111 8055 109682119
Synovial cyst 29.98 10.00 177 898948 11253 109678921
Transaminases increased 29.96 10.00 350 898775 63040 109627134
Blindness 29.93 10.00 173 898952 36186 109653988
Swelling face 29.91 10.00 549 898576 91772 109598402
Pruritus genital 29.90 10.00 8 899117 6514 109683660
Face oedema 29.89 10.00 155 898970 33314 109656860
Tongue disorder 29.86 10.00 209 898916 14089 109676085
Hyperlactacidaemia 29.84 10.00 15 899110 8271 109681903
Drug effective for unapproved indication 29.82 10.00 43 899082 14124 109676050
Tardive dyskinesia 29.79 10.00 40 899085 13539 109676635
Nail disorder 29.74 10.00 648 898477 57287 109632887
Acute respiratory failure 29.52 10.00 432 898693 74828 109615346
Virologic failure 29.47 10.00 3 899122 4949 109685225
Tendonitis 29.34 10.00 333 898792 25750 109664424
Paranoia 29.29 10.00 89 899036 22285 109667889
Acidosis 29.23 10.00 90 899035 22441 109667733
Endophthalmitis 29.21 10.00 15 899110 8172 109682002
Affective disorder 29.11 10.00 29 899096 11212 109678962
Cerebral haemorrhage 29.07 10.00 363 898762 64605 109625569
Acute coronary syndrome 28.80 10.00 94 899031 23018 109667156
Drug tolerance 28.74 10.00 232 898893 16353 109673821
Chronic graft versus host disease 28.64 10.00 21 899104 9436 109680738
Septic shock 28.59 10.00 1020 898105 156508 109533666
Prescribed overdose 28.57 10.00 923 898202 86658 109603516
Spinal stenosis 28.51 10.00 258 898867 18798 109671376
Mental status changes 28.46 10.00 441 898684 75681 109614493
Smear cervix abnormal 28.41 10.00 66 899059 2646 109687528
Product preparation error 28.25 10.00 28 899097 10851 109679323
Myopathy 28.10 10.00 106 899019 24854 109665320
Drug tolerance decreased 28.06 10.00 345 898780 27195 109662979
Skin ulcer 27.79 10.00 696 898429 62949 109627225
Metastases to bone 27.62 10.00 146 898979 31226 109658948
Tenderness 27.55 10.00 363 898762 29074 109661100
Dyskinesia 27.54 10.00 276 898849 51170 109639004
Stevens-Johnson syndrome 27.51 10.00 246 898879 46655 109643519
Accidental death 27.44 10.00 4 899121 5005 109685169
Strongyloidiasis 27.28 10.00 4 899121 4982 109685192
Device leakage 27.11 10.00 56 899069 15992 109674182
Pulseless electrical activity 27.04 10.00 60 899065 16697 109673477
Eating disorder 26.95 10.00 144 898981 30714 109659460
Venoocclusive disease 26.91 10.00 9 899116 6341 109683833
Gamma-glutamyltransferase increased 26.89 10.00 344 898781 60965 109629209
Nasal polyps 26.87 10.00 41 899084 13159 109677015
Spirometry abnormal 26.86 10.00 102 899023 5395 109684779
Product administered to patient of inappropriate age 26.83 10.00 16 899109 8020 109682154
Exposure via ingestion 26.65 10.00 4 899121 4896 109685278
Neck mass 26.55 10.00 93 899032 4728 109685446
Vomiting 26.50 10.00 6789 892336 903886 108786288
Bradypnoea 26.46 10.00 19 899106 8630 109681544
Cyanosis 26.41 10.00 138 898987 29603 109660571
Haemoglobin decreased 26.36 10.00 2357 896768 246370 109443804
Non-small cell lung cancer 26.31 10.00 131 898994 7804 109682370
Renal injury 26.28 10.00 72 899053 18641 109671533
Mite allergy 26.18 10.00 105 899020 5698 109684476
Injection site erythema 26.09 10.00 974 898151 93202 109596972
Blood lactic acid increased 26.06 10.00 56 899069 15765 109674409
Scleritis 26.02 10.00 100 899025 5320 109684854
Palmoplantar keratoderma 25.87 10.00 6 899119 5381 109684793
Hypertensive crisis 25.84 10.00 106 899019 24266 109665908
Limb deformity 25.81 10.00 78 899047 3668 109686506
Renal tubular necrosis 25.63 10.00 144 898981 30331 109659843
Ascites 25.54 10.00 567 898558 92241 109597933
Graft versus host disease in skin 25.42 10.00 18 899107 8236 109681938
Haematocrit decreased 25.40 10.00 711 898414 65406 109624768
Myocarditis 25.29 10.00 142 898983 29913 109660261
Injection site pruritus 25.26 10.00 570 898555 50688 109639486
Cross sensitivity reaction 25.20 10.00 7 899118 5560 109684614
Multiple fractures 25.12 10.00 141 898984 8799 109681375
Skin burning sensation 25.02 10.00 92 899033 21733 109668441
Seronegative arthritis 24.86 10.00 188 898937 12989 109677185
Glomerular filtration rate decreased 24.80 10.00 136 898989 28820 109661354
Tuberculosis 24.76 10.00 237 898888 17537 109672637
Asthenia 24.76 10.00 5085 894040 683914 109006260
Product prescribing issue 24.74 10.00 41 899084 12731 109677443
Dehydration 24.73 10.00 1946 897179 277565 109412609
Malignant mediastinal neoplasm 24.70 10.00 42 899083 1336 109688838
Vertigo 24.69 10.00 528 898597 86342 109603832
Rotator cuff repair 24.68 10.00 56 899069 2210 109687964
Bacteraemia 24.57 10.00 223 898902 42167 109648007
Accidental overdose 24.57 10.00 286 898839 51548 109638626
Arthritis infective 24.52 10.00 157 898968 10272 109679902
Affect lability 24.49 10.00 74 899051 18563 109671611
Disability 24.37 10.00 363 898762 29860 109660314
Schizophrenia 24.37 10.00 93 899032 21733 109668441
Toxic skin eruption 24.25 10.00 128 898997 27387 109662787
Paralysis 24.25 10.00 57 899068 15543 109674631
Ankylosing spondylitis 24.20 10.00 213 898912 15399 109674775
Anti-neutrophil cytoplasmic antibody positive vasculitis 24.17 10.00 7 899118 5410 109684764
Antinuclear antibody positive 24.06 10.00 142 898983 9026 109681148
Pre-eclampsia 24.02 10.00 136 898989 8514 109681660
Back injury 23.96 10.00 529 898596 46870 109643304
Lymphopenia 23.86 10.00 210 898915 39960 109650214
Swollen tongue 23.84 10.00 346 898779 60016 109630158
Product administration error 23.72 10.00 191 898934 37026 109653148
Circulatory collapse 23.71 10.00 229 898896 42764 109647410
Hepatitis acute 23.61 10.00 76 899049 18690 109671484
Hypertransaminasaemia 23.58 10.00 109 899016 24146 109666028
Human herpesvirus 6 infection 23.57 10.00 12 899113 6569 109683605
Dust allergy 23.51 10.00 104 899021 5897 109684277
Presyncope 23.46 10.00 269 898856 48618 109641556
Conjunctivitis allergic 23.39 10.00 115 899010 6816 109683358
Anosmia 23.28 10.00 41 899084 12431 109677743
Bronchitis 23.11 10.00 1527 897598 155505 109534669
Colorectal cancer 23.04 10.00 24 899101 9090 109681084
Synovial disorder 23.01 10.00 65 899060 2942 109687232
Visual acuity reduced 22.93 10.00 160 898965 32013 109658161
Breast cancer stage I 22.90 10.00 16 899109 7371 109682803
Hepatic cytolysis 22.65 10.00 313 898812 54740 109635434
Jaundice 22.55 10.00 342 898783 58894 109631280
Gastroenteritis viral 22.50 10.00 368 898757 30858 109659316
Myocardial ischaemia 22.49 10.00 126 898999 26558 109663616
Sputum discoloured 22.46 10.00 134 898991 27811 109662363
Respiration abnormal 22.44 10.00 28 899097 9781 109680393
Mycotic allergy 22.43 10.00 102 899023 5852 109684322
Herpes zoster 22.39 10.00 1087 898038 107292 109582882
Intracranial pressure increased 22.15 10.00 32 899093 10503 109679671
Rheumatoid lung 21.98 10.00 81 899044 4223 109685951
Euglycaemic diabetic ketoacidosis 21.88 10.00 38 899087 11585 109678589
Rales 21.85 10.00 115 899010 24624 109665550
Oliguria 21.81 10.00 78 899047 18579 109671595
Hypotonia 21.80 10.00 61 899064 15684 109674490
Cough 21.79 10.00 3357 895768 458284 109231890
Metastasis 21.78 10.00 21 899104 8246 109681928
International normalised ratio increased 21.69 10.00 538 898587 86234 109603940
Eosinophilic granulomatosis with polyangiitis 21.61 10.00 155 898970 10531 109679643
Personality change 21.61 10.00 35 899090 10967 109679207
Synovial fluid analysis 21.55 10.00 59 899066 2622 109687552
Foot fracture 21.46 10.00 309 898816 25237 109664937
Erectile dysfunction 21.41 10.00 78 899047 18478 109671696
Psychotic symptom 21.39 10.00 3 899122 3864 109686310
Ankle arthroplasty 21.37 10.00 57 899068 2494 109687680
Cleft lip and palate 21.31 10.00 28 899097 704 109689470
Vascular stent thrombosis 21.29 10.00 4 899121 4157 109686017
Anaemia 21.29 10.00 4021 895104 543065 109147109
Colitis ulcerative 21.17 10.00 799 898326 76564 109613610
Pulmonary haemorrhage 21.16 10.00 66 899059 16390 109673784
Brain injury 21.14 10.00 49 899076 13427 109676747
Metabolic disorder 21.05 10.00 33 899092 10477 109679697
Metastases to liver 21.02 10.00 185 898940 35201 109654973
Cytomegalovirus viraemia 20.95 10.00 74 899051 17690 109672484
Hepatitis B reactivation 20.92 10.00 18 899107 7466 109682708
Sneezing 20.91 10.00 163 898962 31821 109658353
Linear IgA disease 20.86 10.00 5 899120 4384 109685790
Muscle spasticity 20.79 10.00 189 898936 35726 109654448
Hypoxia 20.77 10.00 851 898274 128664 109561510
Colitis microscopic 20.77 10.00 49 899076 13345 109676829
Gangrene 20.69 10.00 66 899059 16275 109673899
Cryptococcosis 20.63 10.00 6 899119 4625 109685549
Congestive cardiomyopathy 20.50 10.00 54 899071 14165 109676009
Neutrophilia 20.16 10.00 33 899092 10296 109679878
Methaemoglobinaemia 20.12 10.00 27 899098 9141 109681033
Cytomegalovirus chorioretinitis 20.11 10.00 17 899108 7111 109683063
Anticholinergic syndrome 20.10 10.00 5 899120 4275 109685899
Disturbance in social behaviour 20.03 10.00 8 899117 5050 109685124
Loose body in joint 20.02 10.00 39 899086 1381 109688793
Arterial occlusive disease 19.96 10.00 61 899064 15247 109674927
Syringe issue 19.96 10.00 29 899096 9496 109680678
Psychiatric decompensation 19.93 10.00 11 899114 5754 109684420
Jaundice cholestatic 19.93 10.00 57 899068 14551 109675623
Hydrops foetalis 19.90 10.00 28 899097 753 109689421
Therapy interrupted 19.88 10.00 285 898840 49537 109640637
Transplant dysfunction 19.88 10.00 23 899102 8305 109681869
Blood bilirubin increased 19.82 10.00 468 898657 75504 109614670
Liver function test increased 19.76 10.00 895 898230 87653 109602521
Anhedonia 19.75 10.00 62 899063 15366 109674808
Drug screen positive 19.71 10.00 14 899111 6396 109683778
Type I hypersensitivity 19.61 10.00 14 899111 6379 109683795
Behaviour disorder 19.60 10.00 30 899095 9617 109680557
Toxic encephalopathy 19.57 10.00 61 899064 15153 109675021
Red blood cell count decreased 19.53 10.00 687 898438 65236 109624938
Tenosynovitis stenosans 19.41 10.00 69 899056 3534 109686640
Temperature intolerance 19.35 10.00 54 899071 13896 109676278
Diabetes mellitus inadequate control 19.35 10.00 152 898973 29623 109660551
Fracture delayed union 19.27 10.00 50 899075 2151 109688023
Acute pulmonary oedema 19.25 10.00 72 899053 16924 109673250
Shock haemorrhagic 19.18 10.00 136 898989 27111 109663063
Panic attack 19.15 10.00 147 898978 28793 109661381
Laryngospasm 19.12 10.00 7 899118 4661 109685513
Ultrasound antenatal screen 19.02 10.00 26 899099 680 109689494
Hallucination, auditory 18.95 10.00 131 898994 26266 109663908
Skin papilloma 18.87 10.00 108 899017 6788 109683386
Premature delivery 18.84 10.00 352 898773 30280 109659894
Amyloid arthropathy 18.84 10.00 42 899083 1638 109688536
Total lung capacity increased 18.79 10.00 9 899116 5103 109685071
Pharyngeal swelling 18.67 10.00 44 899081 11988 109678186
Acute lymphocytic leukaemia recurrent 18.66 10.00 12 899113 5775 109684399
Dysphonia 18.64 10.00 472 898653 75457 109614717
Nail operation 18.60 10.00 42 899083 1652 109688522
Threatened labour 18.60 10.00 25 899100 643 109689531
Mucocutaneous ulceration 18.59 10.00 27 899098 748 109689426
Osteonecrosis 18.49 10.00 180 898945 33561 109656613
Ulcer 18.38 10.00 470 898655 42646 109647528
Inappropriate antidiuretic hormone secretion 18.37 10.00 181 898944 33670 109656504
Tumour lysis syndrome 18.31 10.00 161 898964 30640 109659534
Erythema 18.25 10.00 2082 897043 289365 109400809
Gene mutation 18.19 10.00 3 899122 3426 109686748
Pulmonary function test abnormal 18.08 10.00 9 899116 4991 109685183
Ketoacidosis 18.08 10.00 34 899091 10053 109680121
Glycosylated haemoglobin increased 18.07 10.00 115 899010 23504 109666670
Mouth ulceration 18.03 10.00 516 898609 47622 109642552
Mood altered 17.98 10.00 101 899024 21274 109668900
Joint injury 17.95 10.00 439 898686 39555 109650619
Wrong product administered 17.88 10.00 39 899086 10921 109679253
Eczema 17.86 10.00 449 898676 71844 109618330
Dizziness 17.83 10.00 5234 893891 692959 108997215
Human antichimeric antibody positive 17.82 10.00 42 899083 1700 109688474
Acute myeloid leukaemia 17.78 10.00 211 898914 37899 109652275
Foot operation 17.75 10.00 111 899014 7202 109682972
Rhinitis allergic 17.75 10.00 80 899045 17842 109672332
Dyspnoea exertional 17.71 10.00 679 898446 103381 109586793
Postoperative wound infection 17.67 10.00 201 898924 15552 109674622
Total lung capacity abnormal 17.63 10.00 79 899046 4504 109685670
Crying 17.52 10.00 129 898996 25499 109664675
Hypoxic-ischaemic encephalopathy 17.51 10.00 28 899097 8819 109681355
Metastases to central nervous system 17.51 10.00 111 899014 22706 109667468
Intraocular pressure increased 17.50 10.00 39 899086 10837 109679337
Lymphatic fistula 17.47 10.00 38 899087 1457 109688717
Complication of device insertion 17.47 10.00 28 899097 8810 109681364
Wound infection pseudomonas 17.37 10.00 51 899074 2360 109687814
Hypogammaglobulinaemia 17.36 10.00 94 899031 19982 109670192
Pain in jaw 17.31 10.00 302 898823 50875 109639299
Complications of transplanted kidney 17.28 10.00 21 899104 7421 109682753
Femoral hernia incarcerated 17.23 10.00 38 899087 1471 109688703
Spondylitis 17.22 10.00 154 898971 11184 109678990
Left ventricular dysfunction 17.16 10.00 116 899009 23377 109666797
Bradykinesia 17.10 10.00 39 899086 10749 109679425
Breast feeding 17.10 10.00 25 899100 697 109689477
Lip oedema 17.07 10.00 22 899103 7578 109682596
Bladder cancer 17.00 10.00 96 899029 20196 109669978
Parkinsonism 16.99 10.00 108 899017 22079 109668095
Varicella zoster virus infection 16.99 10.00 16 899109 6352 109683822
Trisomy 18 16.92 10.00 23 899102 598 109689576
Kounis syndrome 16.87 10.00 14 899111 5911 109684263
Device related infection 16.87 10.00 223 898902 39296 109650878
Mitochondrial toxicity 16.86 10.00 3 899122 3242 109686932
Ingrown hair 16.83 10.00 26 899099 762 109689412
Nasal oedema 16.72 10.00 104 899021 6735 109683439
Pseudomonal sepsis 16.65 10.00 30 899095 9016 109681158
Incorrect dose administered 16.62 10.00 681 898444 102960 109587214
Upper respiratory tract inflammation 16.56 10.00 75 899050 4296 109685878
Accidental exposure to product by child 16.52 10.00 3 899122 3195 109686979
Immune effector cell-associated neurotoxicity syndrome 16.49 10.00 63 899062 14719 109675455
Acute graft versus host disease in intestine 16.46 10.00 13 899112 5626 109684548
Gastrointestinal haemorrhage 16.45 10.00 1141 897984 164377 109525797
Delayed graft function 16.42 10.00 7 899118 4250 109685924
Hypercapnia 16.38 10.00 42 899083 11117 109679057
Corneal oedema 16.34 10.00 3 899122 3170 109687004
Normal newborn 16.13 10.00 259 898866 21637 109668537
Cerebral toxoplasmosis 16.12 10.00 3 899122 3139 109687035
Bone disorder 16.11 10.00 252 898873 20940 109669234
Capillary leak syndrome 16.07 10.00 10 899115 4898 109685276
Polyhydramnios 16.00 10.00 43 899082 1890 109688284
Stress cardiomyopathy 15.99 10.00 70 899055 15736 109674438
Nightmare 15.97 10.00 221 898904 38642 109651532
Back pain 15.95 10.00 2712 896413 368284 109321890
Multiple allergies 15.90 10.00 49 899076 12214 109677960
Rash morbilliform 15.89 10.00 25 899100 7926 109682248
Epistaxis 15.87 10.00 882 898243 129490 109560684
Hyperprolactinaemia 15.86 10.00 18 899107 6557 109683617
Post procedural infection 15.85 10.00 177 898948 13632 109676542
Frequent bowel movements 15.81 10.00 721 898404 70669 109619505
Throat tightness 15.79 10.00 185 898940 33304 109656870
Haematemesis 15.73 10.00 363 898762 58745 109631429
Oesophageal carcinoma 15.69 10.00 45 899080 11479 109678695
Decreased appetite 15.64 10.00 4221 894904 471625 109218549
Abortion incomplete 15.62 10.00 3 899122 3069 109687105
Hypoventilation 15.60 10.00 26 899099 8055 109682119
Renal cancer 15.57 10.00 54 899071 12980 109677194
Epilepsy 15.56 10.00 979 898146 99230 109590944
Treatment noncompliance 15.53 10.00 463 898662 72527 109617647
Short stature 15.50 10.00 30 899095 1057 109689117
Defaecation disorder 15.47 10.00 26 899099 819 109689355
Extra dose administered 15.47 10.00 49 899076 12110 109678064
Mental impairment 15.45 10.00 114 899011 22525 109667649
Bronchial secretion retention 15.42 10.00 11 899114 5013 109685161
Breast cancer female 15.34 10.00 51 899074 12417 109677757
Wrong patient received product 15.32 10.00 19 899106 6655 109683519
Skin neoplasm excision 15.27 10.00 44 899081 2014 109688160
Hypomagnesaemia 15.17 10.00 374 898751 59996 109630178
Drug abuser 15.13 10.00 13 899112 5396 109684778
Ataxia 15.11 10.00 164 898961 29944 109660230
Nervous system disorder 15.04 10.00 175 898950 31546 109658628
Hyperlipidaemia 15.04 10.00 203 898922 35645 109654529
Squamous cell carcinoma of lung 15.00 10.00 53 899072 2706 109687468
Body height below normal 14.93 10.00 44 899081 2040 109688134
Post-traumatic stress disorder 14.91 10.00 19 899106 6577 109683597
Vascular purpura 14.87 10.00 6 899119 3765 109686409
Bone density increased 14.86 10.00 28 899097 967 109689207
Rash macular 14.84 10.00 223 898902 38463 109651711
Normochromic normocytic anaemia 14.82 10.00 167 898958 12890 109677284
Acute myeloid leukaemia recurrent 14.81 10.00 12 899113 5127 109685047
Bulbospinal muscular atrophy congenital 14.81 10.00 7 899118 33 109690141
Neck pain 14.80 10.00 1178 897947 121952 109568222
Iodine allergy 14.79 10.00 23 899102 678 109689496
Ventricular arrhythmia 14.78 10.00 38 899087 10049 109680125
Cardiopulmonary failure 14.73 10.00 26 899099 7877 109682297
Respiratory tract congestion 14.72 10.00 170 898955 30687 109659487
Pulmonary embolism 14.63 10.00 1523 897602 212951 109477223
Pulmonary congestion 14.62 10.00 171 898954 30795 109659379
Atrioventricular block 14.60 10.00 79 899046 16798 109673376
Heparin-induced thrombocytopenia 14.56 10.00 46 899079 11378 109678796
Staphylococcal infection 14.55 10.00 445 898680 69499 109620675
Antibody test positive 14.52 10.00 57 899068 3063 109687111
Spinal compression fracture 14.48 10.00 220 898905 18172 109672002
Illness 14.47 10.00 534 898591 81637 109608537
Compartment syndrome 14.46 10.00 16 899109 5894 109684280
Immunisation 14.41 10.00 4 899121 3179 109686995
Metastases to lung 14.40 10.00 119 899006 22944 109667230
Joint noise 14.37 10.00 81 899044 5062 109685112
Small for dates baby 14.36 10.00 22 899103 640 109689534
Placental disorder 14.34 10.00 28 899097 993 109689181
Device issue 14.33 10.00 196 898929 34339 109655835
Complication of device removal 14.33 10.00 10 899115 4610 109685564
Hypertriglyceridaemia 14.32 10.00 75 899050 16079 109674095
Incoherent 14.26 10.00 29 899096 8329 109681845
Parvovirus B19 infection 14.26 10.00 3 899122 2878 109687296
Device loosening 14.23 10.00 25 899100 817 109689357
Poor quality device used 14.13 10.00 3 899122 2860 109687314
Skin cancer 14.11 10.00 213 898912 17571 109672603
Pain of skin 14.08 10.00 100 899025 19929 109670245
Malignant melanoma 14.06 10.00 204 898921 16687 109673487
Bacterial sepsis 13.99 10.00 41 899084 10385 109679789
Blood pressure increased 13.95 10.00 2347 896778 256026 109434148
Product dose omission in error 13.93 10.00 123 899002 23389 109666785
Creatinine renal clearance increased 13.92 10.00 6 899119 3619 109686555
Cardiac septal defect 13.90 10.00 27 899098 954 109689220
Vascular device infection 13.90 10.00 78 899047 16434 109673740
Reversible cerebral vasoconstriction syndrome 13.87 10.00 11 899114 4750 109685424
Benign ovarian tumour 13.84 10.00 18 899107 448 109689726
Infection reactivation 13.80 10.00 8 899117 4073 109686101
Immune-mediated myositis 13.80 10.00 18 899107 6168 109684006
Troponin T increased 13.78 10.00 9 899116 4297 109685877
Ulcer haemorrhage 13.75 10.00 259 898866 22312 109667862
Diaphragmatic disorder 13.69 10.00 40 899085 1846 109688328
Epstein-Barr viraemia 13.63 10.00 6 899119 3573 109686601
Increased appetite 13.58 10.00 69 899056 14908 109675266
Mycobacterium chelonae infection 13.57 10.00 4 899121 3056 109687118
Nail injury 13.56 10.00 24 899101 789 109689385
Influenza like illness 13.53 10.00 584 898541 87828 109602346
Fear of injection 13.51 10.00 121 899004 8790 109681384
Pulmonary arterial hypertension 13.46 10.00 185 898940 32383 109657791
Eyelid oedema 13.45 10.00 71 899054 15191 109674983
Maternal exposure during breast feeding 13.37 10.00 69 899056 4169 109686005
Cytomegalovirus colitis 13.37 10.00 23 899102 7038 109683136
Intervertebral disc degeneration 13.35 10.00 214 898911 17871 109672303
Myoglobin blood increased 13.34 10.00 9 899116 4223 109685951
Pallor 13.34 10.00 353 898772 56114 109634060
Foetal distress syndrome 13.33 10.00 21 899104 626 109689548
Coma scale abnormal 13.23 10.00 38 899087 9688 109680486
Eye swelling 13.20 10.00 189 898936 32859 109657315
Cellulitis 13.16 10.00 1193 897932 124823 109565351
Terminal state 13.15 10.00 16 899109 5651 109684523
Pulmonary pain 13.15 10.00 92 899033 6201 109683973
Poor venous access 13.14 10.00 276 898849 24246 109665928
Exercise tolerance decreased 13.10 10.00 52 899073 12015 109678159
Lymph gland infection 13.09 10.00 21 899104 636 109689538
Osteomyelitis 13.07 10.00 390 898735 36210 109653964
Spinal cord compression 13.06 10.00 26 899099 7526 109682648
Walking aid user 13.04 10.00 281 898844 24794 109665380
Placental insufficiency 13.02 10.00 31 899094 1263 109688911
Foetal exposure during pregnancy 13.01 10.00 105 899020 7400 109682774
Hyperreflexia 12.94 10.00 37 899088 9448 109680726
Subarachnoid haemorrhage 12.90 10.00 167 898958 29535 109660639
Extravascular haemolysis 12.89 10.00 17 899108 429 109689745
Hyperventilation 12.88 10.00 34 899091 8913 109681261
Lymphoedema 12.85 10.00 70 899055 14859 109675315
Migraine 12.84 10.00 1589 897536 170063 109520111
Tonic clonic movements 12.83 10.00 4 899121 2948 109687226
Brain death 12.83 10.00 21 899104 6552 109683622
Pneumonia 12.82 10.00 7558 891567 869156 108821018
Atrioventricular block complete 12.82 10.00 103 899022 19979 109670195
Arteriospasm coronary 12.79 10.00 35 899090 9065 109681109
Spinal osteoarthritis 12.79 10.00 233 898892 19950 109670224
Sinus disorder 12.78 10.00 188 898937 32540 109657634
Eye irritation 12.78 10.00 193 898932 33259 109656915
Tension headache 12.78 10.00 38 899087 9580 109680594
Hepatitis B 12.75 10.00 38 899087 9574 109680600
Dysgeusia 12.73 10.00 453 898672 69532 109620642
Heat illness 12.72 10.00 23 899102 769 109689405
Resuscitation 12.71 10.00 4 899121 2929 109687245
Rhinovirus infection 12.67 10.00 51 899074 11738 109678436
Radiation inflammation 12.66 10.00 27 899098 1021 109689153
Hallucinations, mixed 12.54 10.00 33 899092 8660 109681514
Induced labour 12.51 10.00 25 899100 902 109689272
Obsessive-compulsive disorder 12.46 10.00 25 899100 7216 109682958
Acute lung injury 12.45 10.00 5 899120 3146 109687028
Alcohol abuse 12.44 10.00 13 899112 4916 109685258
End stage renal disease 12.43 10.00 113 899012 21360 109668814
Eye pain 12.42 10.00 311 898814 49788 109640386
Sickle cell anaemia 12.41 10.00 23 899102 784 109689390
Cystitis haemorrhagic 12.39 10.00 54 899071 12155 109678019
Disinhibition 12.34 10.00 5 899120 3129 109687045
Troponin increased 12.33 10.00 169 898956 29597 109660577
Enterococcal infection 12.31 10.00 106 899019 20260 109669914
Cyst rupture 12.30 10.00 24 899101 851 109689323
Anaesthetic complication 12.29 10.00 7 899118 3599 109686575
Abortion threatened 12.28 10.00 17 899108 450 109689724
Systemic mycosis 12.26 10.00 8 899117 3821 109686353
Prescription drug used without a prescription 12.25 10.00 16 899109 5480 109684694
Infusion site pain 12.23 10.00 87 899038 17332 109672842
Urinary incontinence 12.21 10.00 301 898824 48286 109641888
Skin plaque 12.19 10.00 57 899068 12588 109677586
Appendicolith 12.18 10.00 67 899058 14188 109675986
Kidney transplant rejection 12.18 10.00 53 899072 11934 109678240
Hand fracture 12.17 10.00 110 899015 8012 109682162
Laryngeal oedema 12.14 10.00 40 899085 9767 109680407
Injection site warmth 12.13 10.00 204 898921 17201 109672973
Product label confusion 12.07 10.00 255 898870 22422 109667752
Aplasia 12.05 10.00 29 899096 7844 109682330
Maternal exposure during delivery 12.04 10.00 7 899118 3558 109686616
Endodontic procedure 12.02 10.00 54 899071 3082 109687092
Urinary retention 12.01 10.00 454 898671 69229 109620945
Brain abscess 11.99 10.00 23 899102 6751 109683423
Areflexia 11.97 10.00 23 899102 6746 109683428
Twin pregnancy 11.94 10.00 25 899100 933 109689241
Fibula fracture 11.93 10.00 71 899054 4527 109685647
Lacrimal disorder 11.89 10.00 18 899107 518 109689656
Enterobacter infection 11.88 10.00 18 899107 5793 109684381
Ischaemic cardiomyopathy 11.88 10.00 30 899095 7981 109682193
Central nervous system mass 11.87 10.00 23 899102 811 109689363
Hereditary angioedema 11.87 10.00 25 899100 7089 109683085
Disorganised speech 11.86 10.00 6 899119 3297 109686877
Cystoid macular oedema 11.81 10.00 4 899121 2796 109687378
Purpura 11.78 10.00 134 898991 24254 109665920
Cell death 11.78 10.00 18 899107 5773 109684401
Blood folate increased 11.76 10.00 19 899106 579 109689595
Fanconi syndrome 11.76 10.00 7 899118 3512 109686662
Haemorrhage in pregnancy 11.75 10.00 35 899090 1633 109688541
Wall motion score index abnormal 11.74 10.00 23 899102 818 109689356
Device malfunction 11.73 10.00 142 898983 25416 109664758
Prostatic specific antigen increased 11.71 10.00 57 899068 12454 109677720
Psychomotor retardation 11.69 10.00 29 899096 7763 109682411
Polycythaemia 11.69 10.00 6 899119 3269 109686905
Neurological symptom 11.64 10.00 185 898940 15423 109674751
Cervical incompetence 11.61 10.00 18 899107 529 109689645
Impaired gastric emptying 11.56 10.00 62 899063 13213 109676961
Prostate cancer stage IV 11.50 10.00 3 899122 2485 109687689
Acquired gene mutation 11.50 10.00 4 899121 2750 109687424
Mitral valve incompetence 11.49 10.00 196 898929 33133 109657041
Skin necrosis 11.49 10.00 242 898883 21270 109668904
Ototoxicity 11.47 10.00 10 899115 4121 109686053
Cardiac monitoring abnormal 11.46 10.00 3 899122 0 109690174
Marasmus 11.45 10.00 35 899090 1656 109688518
Hepatic cyst 11.45 10.00 105 899020 7678 109682496
Anger 11.45 10.00 99 899026 18908 109671266
Coronary arterial stent insertion 11.45 10.00 19 899106 5896 109684278
Tinnitus 11.44 10.00 390 898735 60150 109630024
Iron overload 11.42 10.00 41 899084 2110 109688064
Altered state of consciousness 11.41 10.00 369 898756 57257 109632917
Insurance issue 11.35 10.00 46 899079 10566 109679608
Lipodystrophy acquired 11.34 10.00 12 899113 4512 109685662
Product monitoring error 11.34 10.00 36 899089 8891 109681283
Hypertonia 11.32 10.00 33 899092 8373 109681801
Polyuria 11.32 10.00 91 899034 17647 109672527
Hypovolaemia 11.30 10.00 117 899008 21557 109668617
Quadriparesis 11.23 10.00 13 899112 4694 109685480
Nephrogenic diabetes insipidus 11.21 10.00 3 899122 2442 109687732
Priapism 11.18 10.00 19 899106 5842 109684332
Drooling 11.16 10.00 26 899099 7113 109683061
Stillbirth 11.16 10.00 66 899059 4198 109685976
Lower respiratory tract congestion 11.15 10.00 72 899053 4724 109685450
Dermatitis bullous 11.15 10.00 90 899035 17439 109672735
Hypernatraemia 11.14 10.00 92 899033 17741 109672433
Cardiac dysfunction 11.13 10.00 21 899104 6202 109683972
Generalised oedema 11.10 10.00 179 898946 30525 109659649
Facial pain 11.07 10.00 76 899049 15263 109674911
Drug eruption 11.04 10.00 538 898587 53121 109637053
Joint lock 11.03 10.00 58 899067 3530 109686644
Oculogyric crisis 10.98 10.00 9 899116 3823 109686351
Middle insomnia 10.97 10.00 110 899015 20392 109669782
Weight decreased 10.94 10.00 4097 895028 463960 109226214
Ligament rupture 10.92 10.00 63 899062 3972 109686202
Tetany 10.92 10.00 8 899117 3596 109686578
Paresis 10.90 10.00 14 899111 4830 109685344
Oropharyngeal pain 10.88 10.00 1258 897867 134018 109556156
Human anti-human antibody test 10.87 10.00 15 899110 396 109689778
Lung adenocarcinoma 10.86 10.00 122 899003 9409 109680765
Skin lesion 10.86 10.00 328 898797 51303 109638871
Systemic candida 10.81 10.00 43 899082 9931 109680243
Psychomotor skills impaired 10.80 10.00 26 899099 7032 109683142
Loss of libido 10.80 10.00 6 899119 3127 109687047
Pancreatic steatosis 10.78 10.00 36 899089 1786 109688388
Hypertension 10.78 10.00 4449 894676 505635 109184539
Cerebral haematoma 10.78 10.00 41 899084 9591 109680583
Accident 10.78 10.00 49 899076 10903 109679271
Major depression 10.76 10.00 47 899078 10574 109679600
Nervousness 10.76 10.00 223 898902 36628 109653546
Procedural pain 10.75 10.00 214 898911 35351 109654823
Plasma cell myeloma recurrent 10.73 10.00 26 899099 7016 109683158
Ventricular extrasystoles 10.70 10.00 125 899000 22516 109667658
Tender joint count increased 10.67 10.00 15 899110 403 109689771
Hypovolaemic shock 10.65 10.00 72 899053 14511 109675663
Transient aphasia 10.65 10.00 20 899105 689 109689485
Cholestatic liver injury 10.64 10.00 28 899097 7348 109682826
Unevaluable event 10.63 10.00 384 898741 58843 109631331
Pancreatitis 10.62 10.00 637 898488 92896 109597278
Hemianopia 10.62 10.00 5 899120 2863 109687311
Anal fissure 10.60 10.00 125 899000 9756 109680418
Bone density abnormal 10.60 10.00 61 899064 3842 109686332
Metastases to lymph nodes 10.59 10.00 75 899050 14957 109675217
Tachyphrenia 10.59 10.00 3 899122 2353 109687821
Hypocoagulable state 10.58 10.00 4 899121 2611 109687563
Uveitis 10.57 10.00 241 898884 21469 109668705
Bacterial infection 10.56 10.00 289 898836 45747 109644427
Gestational hypertension 10.55 10.00 41 899084 2193 109687981
Apraxia 10.54 10.00 8 899117 3532 109686642
Therapeutic response shortened 10.52 10.00 173 898952 29410 109660764
Clonus 10.48 10.00 36 899089 8680 109681494
Oligoarthritis 10.47 10.00 21 899104 760 109689414
Thinking abnormal 10.45 10.00 76 899049 15064 109675110
Trigeminal neuralgia 10.41 10.00 12 899113 4340 109685834
Oesophageal fibrosis 10.40 10.00 10 899115 176 109689998
Cushingoid 10.37 10.00 143 898982 11569 109678605
Therapeutic product effect incomplete 10.36 10.00 2017 897108 221788 109468386
Pancreatitis necrotising 10.34 10.00 18 899107 5483 109684691
Pruritus 10.33 10.00 4420 894705 577140 109113034
Coronary artery bypass 10.28 10.00 21 899104 6021 109684153
Drug clearance decreased 10.26 10.00 11 899114 4111 109686063
Hepatitis C 10.26 10.00 60 899065 12513 109677661
Erythema of eyelid 10.25 10.00 10 899115 3905 109686269
Serum ferritin increased 10.23 10.00 144 898981 11703 109678471
Clear cell renal cell carcinoma 10.22 10.00 47 899078 2709 109687465
Haemorrhagic transformation stroke 10.20 10.00 6 899119 3031 109687143
COVID-19 pneumonia 10.20 10.00 227 898898 36916 109653258
Alcohol interaction 10.19 10.00 9 899116 3685 109686489
Polydactyly 10.17 10.00 8 899117 106 109690068
Femoral neck fracture 10.16 10.00 151 898974 12416 109677758
Viraemia 10.15 10.00 11 899114 4091 109686083
Eyelid ptosis 10.14 10.00 65 899060 13262 109676912
Heart rate increased 10.13 10.00 1019 898106 142815 109547359
Infusion site reaction 10.13 10.00 201 898924 17481 109672693
Skin fissures 10.08 10.00 139 898986 24319 109665855
Carcinoid tumour of the small bowel 10.08 10.00 15 899110 425 109689749
Bone fissure 10.08 10.00 18 899107 596 109689578
Skin abrasion 10.07 10.00 186 898939 15965 109674209
Device breakage 10.05 10.00 68 899057 13701 109676473
Renal tubular atrophy 10.05 10.00 3 899122 2273 109687901
Retching 10.05 10.00 127 898998 22555 109667619
Poor quality sleep 10.05 10.00 164 898961 27913 109662261
Vertebral osteophyte 10.02 10.00 17 899108 540 109689634
Dyspepsia 10.00 10.00 1732 897393 189233 109500941

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A02AA02 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR ACID RELATED DISORDERS
ANTACIDS
Magnesium compounds
ATC A06AD02 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR CONSTIPATION
DRUGS FOR CONSTIPATION
Osmotically acting laxatives
ATC A12CC10 ALIMENTARY TRACT AND METABOLISM
MINERAL SUPPLEMENTS
OTHER MINERAL SUPPLEMENTS
Magnesium
MeSH PA D000863 Antacids
MeSH PA D005765 Gastrointestinal Agents
CHEBI has role CHEBI:33287 fertilizer
CHEBI has role CHEBI:65265 antacid

Related Drugs by ATC class:

A02AA Magnesium compounds 4 drugs
magnesium carbonatemagnesium hydroxidemagnesium peroxidemagnesium silicate
A06AD Osmotically acting laxatives 13 drugs
lactitollactulosemacrogolmagnesium carbonatemagnesium citratemagnesium peroxidemagnesium sulfatemannitolpentaerythritolsodium phosphatesodium sulfatesodium tartrate show all 13 →
A12CC Magnesium 9 drugs
magnesium aspartatemagnesium chloridemagnesium citratemagnesium gluconatemagnesium lactatemagnesium levulinatemagnesium orotatemagnesium pidolatemagnesium sulfate

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Hypocalcemia indication 5291005
Constipation indication 14760008 DOID:2089
Osteoporosis indication 64859006 DOID:11476
Postmenopausal osteoporosis indication 102447009
Indigestion indication 162031009
Hypomagnesemia indication 190855004
Incomplete passage of stool indication 249515001
Peptic ulcer contraindication 13200003 DOID:750
Bipolar disorder contraindication 13746004 DOID:3312
Hyperkalemia contraindication 14140009
Hypocupremia contraindication 19577007
Hyperphosphatemia contraindication 20165001 DOID:0050459
Hypervitaminosis D contraindication 27712000 DOID:9971
Sarcoidosis contraindication 31541009 DOID:11335
Dehydration contraindication 34095006
Conduction disorder of the heart contraindication 44808001
Low blood pressure contraindication 45007003
Chronic heart failure contraindication 48447003
Metabolic acidosis contraindication 59455009
Diarrhea contraindication 62315008
Blood coagulation disorder contraindication 64779008 DOID:1247
Hypercalcemia contraindication 66931009 DOID:12678
Hyperparathyroidism contraindication 66999008 DOID:13543
Hypercalciuria contraindication 71938000
Gastrointestinal hemorrhage contraindication 74474003
Phototoxicity contraindication 84326006
Kidney disease contraindication 90708001 DOID:557
Kidney stone contraindication 95570007
Neoplasm of endometrium contraindication 123844007 DOID:1380
Gastrointestinal obstruction contraindication 126765001
Seizure disorder contraindication 128613002
Impaired renal function disorder contraindication 197663003
Osteolysis contraindication 203522001
Hypomania contraindication 231496004
Gastroparesis contraindication 235675006
Disease of liver contraindication 235856003 DOID:409
Rhabdomyolysis contraindication 240131006
Endometrial carcinoma contraindication 254878006 DOID:2871
Esophageal dysmotility contraindication 266434009 DOID:9192
Arteriosclerosis obliterans contraindication 361133006 DOID:5160
Primary adrenocortical insufficiency contraindication 373662000
Ketoacidosis in diabetes mellitus contraindication 420422005 DOID:1837
Carcinoma of female breast contraindication 447782002
Genitourinary Tract Infections contraindication
Vitamin K Deficiency Induced Hypoprothrombinemia contraindication
Esophageal Compression contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRoutePatent numberPatent expiration datePatent use
12GM/BOT;3.5GM/BOT;10MG/BOT CLENPIQ FERRING PHARMS INC N209589 Nov. 28, 2017 RX SOLUTION ORAL 11191753 June 23, 2034 FOR CLEANSING OF THE COLON AS A PREPARATION FOR COLONOSCOPY
12GM/BOT;3.5GM/BOT;10MG/BOT CLENPIQ FERRING PHARMS INC N209589 Nov. 28, 2017 RX SOLUTION ORAL 12576072 June 23, 2034 FOR CLEANSING OF THE COLON AS A PREPARATION FOR COLONOSCOPY
12GM/BOT;3.5GM/BOT;10MG/BOT CLENPIQ FERRING PHARMS INC N209589 Nov. 28, 2017 RX SOLUTION ORAL 9827231 June 26, 2034 FOR CLEANSING THE LARGE INTESTINE AS A PREPARATION FOR COLONOSCOPY

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4020248 VUID
N0000148146 NUI
D01167 KEGG_DRUG
4017641 VANDF
4017717 VANDF
4020248 VANDF
C0024477 UMLSCUI
CHEBI:31794 CHEBI
CHEMBL1200572 ChEMBL_ID
D008277 MESH_DESCRIPTOR_UI
DB01377 DRUGBANK_ID
3A3U0GI71G UNII
14792 PUBCHEM_CID
6582 RXNORM
40492 MMSL
42624 MMSL
5015 MMSL
5585 MMSL
d03797 MMSL
000788 NDDF
002435 NDDF
419521006 SNOMEDCT_US
66389008 SNOMEDCT_US
3A3U0GI71G INXIGHT DRUGS

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Calcemin Advance HUMAN OTC DRUG LABEL 5 0280-0272 TABLET, FILM COATED 40 mg ORAL Export only 1 sections
Calcemin Silver HUMAN OTC DRUG LABEL 3 0280-0273 TABLET, FILM COATED 40 mg ORAL Export only 2 sections
Magnesium Oxide HUMAN OTC DRUG LABEL 1 0603-0209 TABLET 400 mg ORAL OTC Monograph Drug 12 sections
Magnesium Oxide HUMAN OTC DRUG LABEL 1 0603-0213 TABLET 253 mg ORAL OTC Monograph Drug 12 sections
VitafolUltra HUMAN PRESCRIPTION DRUG LABEL 17 0642-0093 CAPSULE, LIQUID FILLED 20 mg ORAL unapproved drug other 13 sections
Select OB HUMAN PRESCRIPTION DRUG LABEL 15 0642-0120 TABLET, CHEWABLE 25 mg ORAL UNAPPROVED DRUG OTHER 13 sections
Strovite OneCaplets HUMAN PRESCRIPTION DRUG LABEL 20 0642-0207 TABLET 50 mg ORAL unapproved drug other 14 sections
Vitafol Fe Plus HUMAN PRESCRIPTION DRUG LABEL 17 0642-7473 CAPSULE, LIQUID FILLED 20 mg ORAL unapproved drug other 14 sections
Marnatal F HUMAN PRESCRIPTION DRUG LABEL 13 0682-1570 CAPSULE 25 mg ORAL UNAPPROVED DRUG OTHER 4 sections
BACMIN HUMAN PRESCRIPTION DRUG LABEL 19 0682-3001 TABLET, COATED 50 mg ORAL UNAPPROVED DRUG OTHER 10 sections
Magnesium Oxide HUMAN OTC DRUG LABEL 1 10135-583 TABLET 400 mg ORAL OTC MONOGRAPH FINAL 12 sections
magnesium oxide HUMAN OTC DRUG LABEL 1 10135-721 TABLET 420 mg ORAL OTC Monograph Drug 9 sections
Magnesium Oxide HUMAN OTC DRUG LABEL 1 10135-786 TABLET 400 mg ORAL OTC Monograph Drug 12 sections
Quflora Pediatric Drops HUMAN PRESCRIPTION DRUG LABEL 13 15370-100 LIQUID 10 mg ORAL UNAPPROVED DRUG OTHER 11 sections
Quflora Pediatric Drops HUMAN PRESCRIPTION DRUG LABEL 13 15370-101 LIQUID 12 mg ORAL UNAPPROVED DRUG OTHER 11 sections
Quflora Pediatric HUMAN PRESCRIPTION DRUG LABEL 14 15370-103 TABLET, CHEWABLE 15 mg ORAL UNAPPROVED DRUG OTHER 12 sections
Quflora Pediatric HUMAN PRESCRIPTION DRUG LABEL 14 15370-104 TABLET, CHEWABLE 15 mg ORAL UNAPPROVED DRUG OTHER 12 sections
Quflora Pediatric HUMAN PRESCRIPTION DRUG LABEL 14 15370-105 TABLET, CHEWABLE 15 mg ORAL UNAPPROVED DRUG OTHER 12 sections
TriStart DHA HUMAN PRESCRIPTION DRUG LABEL 15 15370-250 CAPSULE, LIQUID FILLED 30 mg ORAL UNAPPROVED DRUG OTHER 12 sections
Magnesium Oxide HUMAN OTC DRUG LABEL 1 24689-132 TABLET 400 mg ORAL OTC Monograph Drug 11 sections
Mag 440 HUMAN OTC DRUG LABEL 1 28595-710 TABLET 440 mg ORAL OTC Monograph Drug 11 sections
SODIUM PICOSULFATE, MAGNESIUM OXIDE AND ANHYDROUS CITRIC ACID HUMAN PRESCRIPTION DRUG LABEL 3 31722-874 POWDER, METERED 3.50 g ORAL ANDA 25 sections
PNV-Select HUMAN PRESCRIPTION DRUG LABEL 18 42192-320 TABLET, FILM COATED 30 ug ORAL unapproved drug other 10 sections
PNV-Omega HUMAN PRESCRIPTION DRUG LABEL 13 42192-332 CAPSULE, GELATIN COATED 45 mg ORAL unapproved drug other 12 sections
MigralexDr. Mauskop HUMAN OTC DRUG LABEL 2 49886-001 TABLET, COATED 75 mg ORAL OTC monograph not final 13 sections
Magnesium Oxide HUMAN OTC DRUG LABEL 1 50090-7432 TABLET 400 mg ORAL OTC Monograph Drug 14 sections
Magnesium Oxide HUMAN OTC DRUG LABEL 1 50090-7432 TABLET 400 mg ORAL OTC Monograph Drug 14 sections
Nestabs ONE HUMAN PRESCRIPTION DRUG LABEL 10 50967-410 CAPSULE, GELATIN COATED 15 mg ORAL unapproved drug other 12 sections
Magnesium Oxide HUMAN OTC DRUG LABEL 1 53808-0684 TABLET 400 mg ORAL OTC MONOGRAPH FINAL 13 sections
Magnesium Oxide HUMAN OTC DRUG LABEL 1 54738-973 TABLET 400 mg ORAL OTC Monograph Drug 13 sections