magnesium silicate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4513 14987-04-3

Description:

MoleculeDescription

Synonyms:

  • magnesium silicate
  • magnesium trisilicate
  • trisilicalm
  • magnesium mesotrisilicate
hard, porous, granular substance used in vitamin analysis, chromatography, & antibiotic processing
  • Molecular weight: 260.86
  • Formula: Mg2O8Si3
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 144.84
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Dec. 9, 1983 FDA SANOFI AVENTIS US

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Appendicolith 52.33 50.71 11 430 5669 70922334

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A02AA05 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR ACID RELATED DISORDERS
ANTACIDS
Magnesium compounds
MeSH PA D000863 Antacids
MeSH PA D005765 Gastrointestinal Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Peptic ulcer indication 13200003 DOID:750
Heartburn indication 16331000
Indigestion indication 162031009
Gastroesophageal reflux disease indication 235595009 DOID:8534
Gastric Hypersecretory Conditions indication
Hiatal Hernia with Reflux Esophagitis indication
Multiple endocrine adenomas off-label use 60549007
Systemic mast cell disease off-label use 397016004 DOID:349
Stress-Related GI Mucosal Bleeding Prevention off-label use
Hypophosphatemia contraindication 4996001
Constipation contraindication 14760008 DOID:2089
Fecal impaction contraindication 44635007
Chronic heart failure contraindication 48447003
Acute nephropathy contraindication 58574008
Diarrhea contraindication 62315008
Hemorrhoids contraindication 70153002 DOID:9746
Oliguria contraindication 83128009
Kidney disease contraindication 90708001 DOID:557
Gastrointestinal obstruction contraindication 126765001
Chronic diarrhea contraindication 236071009
Aluminum intoxication contraindication 236546003
Edema contraindication 267038008




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
9B9691B2N9 UNII
D03271 KEGG_DRUG
1343-88-0 SECONDARY_CAS_RN
39365-87-2 SECONDARY_CAS_RN
4019384 VANDF
C0851342 UMLSCUI
CHEMBL2109133 ChEMBL_ID
66225 PUBCHEM_CID
DB13249 DRUGBANK_ID
CHEMBL2096633 ChEMBL_ID
C005013 MESH_SUPPLEMENTAL_RECORD_UI
C001671 MESH_SUPPLEMENTAL_RECORD_UI
DB09281 DRUGBANK_ID
1310566 RXNORM
5018 MMSL
5593 MMSL
d03587 MMSL
001121 NDDF
008286 NDDF
21691008 SNOMEDCT_US
387117008 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
GavisconRegular Strength HUMAN OTC DRUG LABEL 2 0135-0096 TABLET, CHEWABLE 14.20 mg ORAL NDA 15 sections
VIRUS BLOCKER CL-40 HUMAN OTC DRUG LABEL 1 80965-201 STICK 80 g TOPICAL unapproved drug other 11 sections