Stem definition | Drug id | CAS RN |
---|---|---|
4200 | 7786-30-3 |
Molecule | Description |
---|---|
Synonyms:
|
Magnesium chloride. An inorganic compound consisting of one magnesium and two chloride ions. The compound is used in medicine as a source of magnesium ions, which are essential for many cellular activities. It has also been used as a cathartic and in alloys.
|
Dose | Unit | Route |
---|---|---|
2.50 | g | O |
0.80 | g | P |
None
Date | Agency | Company | Orphan |
---|---|---|---|
Aug. 13, 1975 | FDA | HOSPIRA |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Death | 5538.65 | 19.52 | 2883 | 23047 | 354349 | 52968787 |
Peritonitis bacterial | 4174.81 | 19.52 | 958 | 24972 | 8547 | 53314589 |
Peritonitis | 3435.78 | 19.52 | 968 | 24962 | 20719 | 53302417 |
Peritoneal dialysis complication | 1709.26 | 19.52 | 371 | 25559 | 2462 | 53320674 |
Fluid overload | 1319.45 | 19.52 | 499 | 25431 | 27332 | 53295804 |
Toxic anterior segment syndrome | 753.03 | 19.52 | 184 | 25746 | 2164 | 53320972 |
Fungal peritonitis | 580.71 | 19.52 | 125 | 25805 | 789 | 53322347 |
Sepsis | 506.75 | 19.52 | 478 | 25452 | 145951 | 53177185 |
Ultrafiltration failure | 497.63 | 19.52 | 104 | 25826 | 557 | 53322579 |
Bloody peritoneal effluent | 461.43 | 19.52 | 93 | 25837 | 402 | 53322734 |
Myocardial infarction | 327.29 | 19.52 | 316 | 25614 | 99038 | 53224098 |
Endophthalmitis | 319.07 | 19.52 | 103 | 25827 | 3484 | 53319652 |
Abdominal distension | 309.46 | 19.52 | 278 | 25652 | 79512 | 53243624 |
Cardiovascular disorder | 284.72 | 19.52 | 133 | 25797 | 12280 | 53310856 |
Hypotension | 281.31 | 19.52 | 468 | 25462 | 253608 | 53069528 |
Drug ineffective | 272.55 | 19.52 | 38 | 25892 | 817207 | 52505929 |
Acute myocardial infarction | 270.62 | 19.52 | 180 | 25750 | 33055 | 53290081 |
Catheter site infection | 263.37 | 19.52 | 97 | 25833 | 4895 | 53318241 |
Procedural pain | 263.19 | 19.52 | 133 | 25797 | 14584 | 53308552 |
Cardiac arrest | 253.57 | 19.52 | 268 | 25662 | 93399 | 53229737 |
Cardiac disorder | 248.84 | 19.52 | 196 | 25734 | 46770 | 53276366 |
Cardio-respiratory arrest | 240.18 | 19.52 | 211 | 25719 | 58547 | 53264589 |
Peritoneal cloudy effluent | 236.56 | 19.52 | 49 | 25881 | 249 | 53322887 |
Cerebrovascular accident | 226.40 | 19.52 | 267 | 25663 | 104907 | 53218229 |
Diabetic foot | 223.33 | 19.52 | 66 | 25864 | 1652 | 53321484 |
Hypopyon | 175.37 | 19.52 | 48 | 25882 | 903 | 53322233 |
Disease complication | 174.56 | 19.52 | 64 | 25866 | 3186 | 53319950 |
Corneal oedema | 166.77 | 19.52 | 54 | 25876 | 1843 | 53321293 |
Cardiac failure | 146.31 | 19.52 | 194 | 25736 | 85650 | 53237486 |
Multimorbidity | 143.99 | 19.52 | 39 | 25891 | 704 | 53322432 |
Device interaction | 141.18 | 19.52 | 31 | 25899 | 217 | 53322919 |
Hypervolaemia | 136.29 | 19.52 | 48 | 25882 | 2125 | 53321011 |
Rheumatoid arthritis | 124.70 | 19.52 | 7 | 25923 | 314524 | 53008612 |
Fatigue | 119.71 | 19.52 | 108 | 25822 | 730398 | 52592738 |
Cardiac failure congestive | 118.83 | 19.52 | 183 | 25747 | 92574 | 53230562 |
Encapsulating peritoneal sclerosis | 115.58 | 19.52 | 29 | 25901 | 382 | 53322754 |
Dehydration | 114.92 | 19.52 | 253 | 25677 | 168157 | 53154979 |
Gangrene | 107.92 | 19.52 | 51 | 25879 | 4826 | 53318310 |
Diabetic complication | 107.82 | 19.52 | 33 | 25897 | 933 | 53322203 |
Headache | 107.73 | 19.52 | 64 | 25866 | 536757 | 52786379 |
Anterior chamber fibrin | 106.82 | 19.52 | 24 | 25906 | 189 | 53322947 |
Hernia | 104.39 | 19.52 | 64 | 25866 | 10196 | 53312940 |
Umbilical hernia | 103.40 | 19.52 | 42 | 25888 | 2760 | 53320376 |
Noninfectious peritonitis | 103.18 | 19.52 | 24 | 25906 | 224 | 53322912 |
Arthralgia | 102.36 | 19.52 | 43 | 25887 | 439740 | 52883396 |
Inadequate aseptic technique in use of product | 100.37 | 19.52 | 21 | 25909 | 113 | 53323023 |
Abdominal pain | 98.15 | 19.52 | 310 | 25620 | 255593 | 53067543 |
Treatment noncompliance | 93.65 | 19.52 | 97 | 25833 | 32938 | 53290198 |
Malnutrition | 91.73 | 19.52 | 68 | 25862 | 14803 | 53308333 |
Drug interaction | 86.51 | 19.52 | 5 | 25925 | 219324 | 53103812 |
Fluid imbalance | 84.61 | 19.52 | 23 | 25907 | 421 | 53322715 |
Device related infection | 79.61 | 19.52 | 75 | 25855 | 22711 | 53300425 |
Fluid retention | 76.26 | 19.52 | 112 | 25818 | 54289 | 53268847 |
Pleuroperitoneal communication | 74.56 | 19.52 | 15 | 25915 | 64 | 53323072 |
Joint swelling | 73.01 | 19.52 | 13 | 25917 | 234625 | 53088511 |
Alopecia | 72.99 | 19.52 | 13 | 25917 | 234570 | 53088566 |
Drug intolerance | 71.85 | 19.52 | 8 | 25922 | 205485 | 53117651 |
Post procedural complication | 70.31 | 19.52 | 61 | 25869 | 16605 | 53306531 |
Peritoneal effluent abnormal | 69.54 | 19.52 | 14 | 25916 | 60 | 53323076 |
Pulmonary oedema | 65.96 | 19.52 | 104 | 25826 | 53619 | 53269517 |
Toxicity to various agents | 64.46 | 19.52 | 14 | 25916 | 219584 | 53103552 |
Anterior chamber cell | 63.96 | 19.52 | 20 | 25910 | 608 | 53322528 |
Extremity necrosis | 63.94 | 19.52 | 26 | 25904 | 1713 | 53321423 |
Marasmus | 62.22 | 19.52 | 19 | 25911 | 533 | 53322603 |
Device occlusion | 60.77 | 19.52 | 39 | 25891 | 6726 | 53316410 |
Infusion related reaction | 60.13 | 19.52 | 4 | 25926 | 155953 | 53167183 |
Abdominal hernia | 58.54 | 19.52 | 34 | 25896 | 4906 | 53318230 |
Anterior chamber inflammation | 56.92 | 19.52 | 16 | 25914 | 333 | 53322803 |
Anterior chamber disorder | 56.72 | 19.52 | 13 | 25917 | 113 | 53323023 |
Off label use | 56.59 | 19.52 | 89 | 25841 | 472123 | 52851013 |
Azotaemia | 55.98 | 19.52 | 32 | 25898 | 4481 | 53318655 |
Pneumoperitoneum | 51.94 | 19.52 | 22 | 25908 | 1607 | 53321529 |
Calciphylaxis | 51.42 | 19.52 | 26 | 25904 | 2849 | 53320287 |
Pneumonia | 50.24 | 19.52 | 354 | 25576 | 406815 | 52916321 |
Completed suicide | 49.26 | 19.52 | 5 | 25925 | 138196 | 53184940 |
Arthropathy | 48.20 | 19.52 | 6 | 25924 | 141447 | 53181689 |
Treatment failure | 47.49 | 19.52 | 4 | 25926 | 128399 | 53194737 |
Pain | 47.12 | 19.52 | 139 | 25791 | 588259 | 52734877 |
Peritoneal disorder | 45.60 | 19.52 | 15 | 25915 | 538 | 53322598 |
Hepatic enzyme increased | 43.86 | 19.52 | 5 | 25925 | 126190 | 53196946 |
Aqueous fibrin | 43.22 | 19.52 | 10 | 25920 | 91 | 53323045 |
Product use issue | 42.81 | 19.52 | 8 | 25922 | 139576 | 53183560 |
Hypoglycaemia | 41.67 | 19.52 | 90 | 25840 | 58923 | 53264213 |
Injection site pain | 40.67 | 19.52 | 4 | 25926 | 113387 | 53209749 |
Wrong product administered | 40.33 | 19.52 | 29 | 25901 | 6019 | 53317117 |
General physical health deterioration | 39.82 | 19.52 | 159 | 25771 | 146783 | 53176353 |
Bacterial translocation | 39.74 | 19.52 | 11 | 25919 | 216 | 53322920 |
Intestinal perforation | 38.87 | 19.52 | 37 | 25893 | 11343 | 53311793 |
Maternal exposure during pregnancy | 38.10 | 19.52 | 14 | 25916 | 155625 | 53167511 |
Dizziness | 37.51 | 19.52 | 78 | 25852 | 372181 | 52950955 |
Procedural complication | 37.09 | 19.52 | 26 | 25904 | 5186 | 53317950 |
Hypophagia | 36.55 | 19.52 | 59 | 25871 | 31003 | 53292133 |
Acute kidney injury | 36.26 | 19.52 | 42 | 25888 | 253826 | 53069310 |
Myalgia | 36.24 | 19.52 | 10 | 25920 | 133481 | 53189655 |
Localised infection | 35.98 | 19.52 | 54 | 25876 | 26662 | 53296474 |
Sinusitis | 35.24 | 19.52 | 19 | 25911 | 168545 | 53154591 |
Anterior chamber flare | 34.66 | 19.52 | 9 | 25921 | 137 | 53322999 |
Tonsillar haemorrhage | 34.63 | 19.52 | 10 | 25920 | 230 | 53322906 |
Failure to thrive | 34.46 | 19.52 | 28 | 25902 | 6964 | 53316172 |
Nasopharyngitis | 34.29 | 19.52 | 26 | 25904 | 192269 | 53130867 |
Cataract operation complication | 34.24 | 19.52 | 9 | 25921 | 144 | 53322992 |
Vitritis | 33.96 | 19.52 | 14 | 25916 | 955 | 53322181 |
Somnolence | 33.50 | 19.52 | 20 | 25910 | 167714 | 53155422 |
Hypersensitivity | 33.27 | 19.52 | 32 | 25898 | 210633 | 53112503 |
Gait disturbance | 33.06 | 19.52 | 18 | 25912 | 158824 | 53164312 |
Fibrin | 32.67 | 19.52 | 7 | 25923 | 43 | 53323093 |
Insomnia | 32.46 | 19.52 | 26 | 25904 | 187046 | 53136090 |
Paraesthesia | 32.01 | 19.52 | 11 | 25919 | 127504 | 53195632 |
Pain in extremity | 31.95 | 19.52 | 56 | 25874 | 284994 | 53038142 |
Eye inflammation | 31.44 | 19.52 | 22 | 25908 | 4375 | 53318761 |
Product container issue | 30.41 | 19.52 | 16 | 25914 | 1903 | 53321233 |
Infection | 30.14 | 19.52 | 164 | 25766 | 172041 | 53151095 |
Depression | 29.85 | 19.52 | 27 | 25903 | 183025 | 53140111 |
Overdose | 29.37 | 19.52 | 8 | 25922 | 107728 | 53215408 |
Anxiety | 28.66 | 19.52 | 32 | 25898 | 196672 | 53126464 |
Neutropenia | 27.76 | 19.52 | 22 | 25908 | 159163 | 53163973 |
Exposure during pregnancy | 27.70 | 19.52 | 13 | 25917 | 124847 | 53198289 |
Multiple organ dysfunction syndrome | 27.55 | 19.52 | 74 | 25856 | 55603 | 53267533 |
Critical illness | 27.46 | 19.52 | 8 | 25922 | 190 | 53322946 |
Asthenia | 27.41 | 19.52 | 271 | 25659 | 343319 | 52979817 |
Exfoliative rash | 27.27 | 19.52 | 17 | 25913 | 2787 | 53320349 |
Erythema | 26.99 | 19.52 | 22 | 25908 | 156947 | 53166189 |
Hypertensive crisis | 26.56 | 19.52 | 34 | 25896 | 14472 | 53308664 |
Systemic lupus erythematosus | 26.40 | 19.52 | 14 | 25916 | 125400 | 53197736 |
Nosocomial infection | 26.21 | 19.52 | 14 | 25916 | 1717 | 53321419 |
Metabolic alkalosis | 26.12 | 19.52 | 17 | 25913 | 3002 | 53320134 |
Condition aggravated | 25.31 | 19.52 | 68 | 25862 | 297066 | 53026070 |
Septic shock | 25.24 | 19.52 | 77 | 25853 | 62152 | 53260984 |
Pyrexia | 24.99 | 19.52 | 106 | 25824 | 403087 | 52920049 |
Hypoaesthesia | 24.98 | 19.52 | 17 | 25913 | 132978 | 53190158 |
Blood glucose decreased | 24.90 | 19.52 | 39 | 25891 | 19977 | 53303159 |
Injection site erythema | 24.61 | 19.52 | 4 | 25926 | 77245 | 53245891 |
Blood potassium decreased | 24.43 | 19.52 | 58 | 25872 | 40402 | 53282734 |
Pancytopenia | 24.32 | 19.52 | 7 | 25923 | 90921 | 53232215 |
Peritoneal effluent leukocyte count increased | 24.20 | 19.52 | 5 | 25925 | 25 | 53323111 |
Haemorrhagic stroke | 24.13 | 19.52 | 21 | 25909 | 5737 | 53317399 |
Cough | 24.05 | 19.52 | 56 | 25874 | 256837 | 53066299 |
Foreign body in eye | 23.76 | 19.52 | 7 | 25923 | 173 | 53322963 |
Hydrothorax | 23.47 | 19.52 | 10 | 25920 | 741 | 53322395 |
Post procedural infection | 23.38 | 19.52 | 24 | 25906 | 8057 | 53315079 |
White blood cell count decreased | 23.26 | 19.52 | 16 | 25914 | 124459 | 53198677 |
Febrile neutropenia | 23.16 | 19.52 | 11 | 25919 | 104925 | 53218211 |
Intestinal ischaemia | 23.01 | 19.52 | 23 | 25907 | 7479 | 53315657 |
Psoriasis | 22.76 | 19.52 | 7 | 25923 | 87082 | 53236054 |
Mental status changes postoperative | 22.54 | 19.52 | 7 | 25923 | 208 | 53322928 |
Intentional overdose | 22.52 | 19.52 | 3 | 25927 | 67202 | 53255934 |
Therapy cessation | 22.42 | 19.52 | 45 | 25885 | 27980 | 53295156 |
Staphylococcus test positive | 22.30 | 19.52 | 17 | 25913 | 3856 | 53319280 |
Complication associated with device | 22.23 | 19.52 | 33 | 25897 | 16132 | 53307004 |
Cardiac procedure complication | 22.22 | 19.52 | 7 | 25923 | 218 | 53322918 |
Palpitations | 22.18 | 19.52 | 11 | 25919 | 102337 | 53220799 |
Blood pressure decreased | 21.85 | 19.52 | 73 | 25857 | 61796 | 53261340 |
Flushing | 21.74 | 19.52 | 4 | 25926 | 70596 | 53252540 |
Osteoarthritis | 21.69 | 19.52 | 4 | 25926 | 70482 | 53252654 |
Catheter site abscess | 21.46 | 19.52 | 5 | 25925 | 47 | 53323089 |
Confusion postoperative | 21.44 | 19.52 | 7 | 25923 | 245 | 53322891 |
Device leakage | 21.20 | 19.52 | 20 | 25910 | 6060 | 53317076 |
Hip fracture | 20.98 | 19.52 | 44 | 25886 | 28213 | 53294923 |
Renal transplant failure | 20.80 | 19.52 | 9 | 25921 | 693 | 53322443 |
Escherichia peritonitis | 20.09 | 19.52 | 4 | 25926 | 16 | 53323120 |
Blood glucose false positive | 20.09 | 19.52 | 4 | 25926 | 16 | 53323120 |
Mental status changes | 19.98 | 19.52 | 53 | 25877 | 39518 | 53283618 |
Oncologic complication | 19.90 | 19.52 | 6 | 25924 | 161 | 53322975 |
Hospitalisation | 19.87 | 19.52 | 5 | 25925 | 71007 | 53252129 |
Post procedural inflammation | 19.78 | 19.52 | 5 | 25925 | 68 | 53323068 |
Catheter site extravasation | 19.59 | 19.52 | 7 | 25923 | 323 | 53322813 |
Pancreatitis | 19.56 | 19.52 | 58 | 25872 | 46084 | 53277052 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Death | 5403.97 | 21.14 | 3697 | 27432 | 378820 | 32103577 |
Peritonitis bacterial | 5195.49 | 21.14 | 1376 | 29753 | 11120 | 32471277 |
Peritonitis | 3976.29 | 21.14 | 1273 | 29856 | 21057 | 32461340 |
Peritoneal dialysis complication | 2338.44 | 21.14 | 587 | 30542 | 3681 | 32478716 |
Fluid overload | 1664.52 | 21.14 | 646 | 30483 | 18975 | 32463422 |
Fungal peritonitis | 773.14 | 21.14 | 195 | 30934 | 1241 | 32481156 |
Ultrafiltration failure | 560.19 | 21.14 | 133 | 30996 | 630 | 32481767 |
Abdominal distension | 462.86 | 21.14 | 387 | 30742 | 50908 | 32431489 |
Toxic anterior segment syndrome | 448.17 | 21.14 | 130 | 30999 | 1482 | 32480915 |
Bloody peritoneal effluent | 395.51 | 21.14 | 95 | 31034 | 477 | 32481920 |
Cardiac disorder | 379.86 | 21.14 | 317 | 30812 | 41549 | 32440848 |
Catheter site infection | 371.85 | 21.14 | 128 | 31001 | 2626 | 32479771 |
Myocardial infarction | 371.41 | 21.14 | 525 | 30604 | 125151 | 32357246 |
Procedural pain | 353.17 | 21.14 | 148 | 30981 | 5281 | 32477116 |
Sepsis | 348.78 | 21.14 | 578 | 30551 | 158256 | 32324141 |
Cardiac arrest | 321.42 | 21.14 | 428 | 30701 | 96348 | 32386049 |
Peritoneal cloudy effluent | 307.17 | 21.14 | 74 | 31055 | 377 | 32482020 |
Cardiovascular disorder | 259.66 | 21.14 | 149 | 30980 | 10613 | 32471784 |
Drug ineffective | 256.45 | 21.14 | 33 | 31096 | 383444 | 32098953 |
Diabetic foot | 242.70 | 21.14 | 95 | 31034 | 2831 | 32479566 |
Cardiac failure | 237.07 | 21.14 | 360 | 30769 | 91313 | 32391084 |
Hernia | 227.57 | 21.14 | 131 | 30998 | 9384 | 32473013 |
Multimorbidity | 194.23 | 21.14 | 54 | 31075 | 521 | 32481876 |
Fluid retention | 192.28 | 21.14 | 177 | 30952 | 26373 | 32456024 |
Cardio-respiratory arrest | 189.18 | 21.14 | 250 | 30879 | 55739 | 32426658 |
Inguinal hernia | 186.22 | 21.14 | 108 | 31021 | 7844 | 32474553 |
Acute kidney injury | 178.29 | 21.14 | 33 | 31096 | 293435 | 32188962 |
Acute myocardial infarction | 178.28 | 21.14 | 241 | 30888 | 54908 | 32427489 |
Endophthalmitis | 174.18 | 21.14 | 82 | 31047 | 3867 | 32478530 |
Noninfectious peritonitis | 155.28 | 21.14 | 38 | 31091 | 209 | 32482188 |
Hypotension | 151.26 | 21.14 | 502 | 30627 | 215608 | 32266789 |
Hypervolaemia | 146.97 | 21.14 | 64 | 31065 | 2510 | 32479887 |
Off label use | 145.46 | 21.14 | 56 | 31073 | 306264 | 32176133 |
Drug interaction | 144.93 | 21.14 | 19 | 31110 | 218166 | 32264231 |
Toxicity to various agents | 144.82 | 21.14 | 6 | 31123 | 178035 | 32304362 |
Gangrene | 140.70 | 21.14 | 76 | 31053 | 4806 | 32477591 |
Inadequate aseptic technique in use of product | 140.24 | 21.14 | 33 | 31096 | 149 | 32482248 |
Diabetic complication | 136.28 | 21.14 | 46 | 31083 | 886 | 32481511 |
Fluid imbalance | 133.18 | 21.14 | 38 | 31091 | 406 | 32481991 |
Fatigue | 128.25 | 21.14 | 90 | 31039 | 350611 | 32131786 |
Peritoneal disorder | 125.81 | 21.14 | 36 | 31093 | 389 | 32482008 |
Device related infection | 124.86 | 21.14 | 117 | 31012 | 17816 | 32464581 |
Umbilical hernia | 124.52 | 21.14 | 67 | 31062 | 4203 | 32478194 |
Cerebrovascular accident | 123.46 | 21.14 | 262 | 30867 | 86058 | 32396339 |
Azotaemia | 117.94 | 21.14 | 70 | 31059 | 5304 | 32477093 |
Dehydration | 115.63 | 21.14 | 327 | 30802 | 128631 | 32353766 |
Peritoneal effluent abnormal | 113.15 | 21.14 | 27 | 31102 | 131 | 32482266 |
Disease complication | 107.19 | 21.14 | 53 | 31076 | 2786 | 32479611 |
Encapsulating peritoneal sclerosis | 105.08 | 21.14 | 35 | 31094 | 646 | 32481751 |
Localised infection | 99.84 | 21.14 | 96 | 31033 | 15091 | 32467306 |
Device interaction | 94.42 | 21.14 | 31 | 31098 | 546 | 32481851 |
Treatment noncompliance | 92.59 | 21.14 | 122 | 31007 | 27080 | 32455317 |
Headache | 87.89 | 21.14 | 39 | 31090 | 196158 | 32286239 |
Cardiac failure congestive | 87.84 | 21.14 | 227 | 30902 | 84625 | 32397772 |
Post procedural complication | 85.41 | 21.14 | 79 | 31050 | 11828 | 32470569 |
Neutropenia | 74.24 | 21.14 | 22 | 31107 | 142153 | 32340244 |
Hypopyon | 73.75 | 21.14 | 25 | 31104 | 488 | 32481909 |
Dizziness | 71.02 | 21.14 | 58 | 31071 | 209560 | 32272837 |
Corneal oedema | 70.06 | 21.14 | 32 | 31097 | 1406 | 32480991 |
Abdominal pain | 69.27 | 21.14 | 305 | 30824 | 149224 | 32333173 |
Somnolence | 66.54 | 21.14 | 10 | 31119 | 103787 | 32378610 |
Completed suicide | 66.53 | 21.14 | 6 | 31123 | 92511 | 32389886 |
Drug abuse | 64.19 | 21.14 | 3 | 31126 | 80240 | 32402157 |
Thrombocytopenia | 62.50 | 21.14 | 32 | 31097 | 148267 | 32334130 |
Product use in unapproved indication | 61.79 | 21.14 | 6 | 31123 | 87198 | 32395199 |
Platelet count decreased | 61.15 | 21.14 | 17 | 31112 | 114574 | 32367823 |
Device occlusion | 60.14 | 21.14 | 51 | 31078 | 6807 | 32475590 |
Arthralgia | 59.68 | 21.14 | 34 | 31095 | 148414 | 32333983 |
Complication associated with device | 59.17 | 21.14 | 48 | 31081 | 6024 | 32476373 |
Overdose | 59.12 | 21.14 | 7 | 31122 | 87070 | 32395327 |
Febrile neutropenia | 58.00 | 21.14 | 21 | 31108 | 119545 | 32362852 |
Pancytopenia | 57.99 | 21.14 | 9 | 31120 | 91226 | 32391171 |
White blood cell count decreased | 55.74 | 21.14 | 10 | 31119 | 91188 | 32391209 |
Anterior chamber fibrin | 55.28 | 21.14 | 15 | 31114 | 131 | 32482266 |
Failure to thrive | 54.82 | 21.14 | 53 | 31076 | 8382 | 32474015 |
Disease progression | 54.24 | 21.14 | 9 | 31120 | 86853 | 32395544 |
Extremity necrosis | 53.86 | 21.14 | 29 | 31100 | 1821 | 32480576 |
Anterior chamber cell | 51.26 | 21.14 | 18 | 31111 | 392 | 32482005 |
Anxiety | 49.82 | 21.14 | 15 | 31114 | 95990 | 32386407 |
Myalgia | 47.33 | 21.14 | 10 | 31119 | 81220 | 32401177 |
Marasmus | 46.90 | 21.14 | 19 | 31110 | 620 | 32481777 |
Cardiac procedure complication | 46.79 | 21.14 | 15 | 31114 | 244 | 32482153 |
Infection | 46.37 | 21.14 | 182 | 30947 | 84533 | 32397864 |
Swelling | 45.56 | 21.14 | 108 | 31021 | 38114 | 32444283 |
Pulmonary oedema | 44.98 | 21.14 | 121 | 31008 | 46146 | 32436251 |
Calciphylaxis | 44.18 | 21.14 | 22 | 31107 | 1174 | 32481223 |
Abdominal discomfort | 43.71 | 21.14 | 130 | 30999 | 52494 | 32429903 |
Hip fracture | 43.10 | 21.14 | 55 | 31074 | 11820 | 32470577 |
Alanine aminotransferase increased | 43.07 | 21.14 | 11 | 31118 | 78468 | 32403929 |
Postoperative wound infection | 42.95 | 21.14 | 36 | 31093 | 4728 | 32477669 |
Nausea | 42.52 | 21.14 | 161 | 30968 | 320688 | 32161709 |
Pyrexia | 42.11 | 21.14 | 161 | 30968 | 319807 | 32162590 |
Renal impairment | 40.00 | 21.14 | 19 | 31110 | 91953 | 32390444 |
Abdominal hernia | 39.56 | 21.14 | 28 | 31101 | 2865 | 32479532 |
Foreign body in eye | 39.03 | 21.14 | 11 | 31118 | 112 | 32482285 |
Pleuroperitoneal communication | 38.18 | 21.14 | 9 | 31120 | 41 | 32482356 |
Rhabdomyolysis | 37.74 | 21.14 | 9 | 31120 | 67256 | 32415141 |
Mycobacterial peritonitis | 37.32 | 21.14 | 9 | 31120 | 46 | 32482351 |
Anaemia | 35.93 | 21.14 | 103 | 31026 | 223521 | 32258876 |
Diarrhoea | 35.92 | 21.14 | 204 | 30925 | 364598 | 32117799 |
Hydrothorax | 35.90 | 21.14 | 15 | 31114 | 530 | 32481867 |
Leukopenia | 35.85 | 21.14 | 7 | 31122 | 60115 | 32422282 |
Agitation | 35.57 | 21.14 | 6 | 31123 | 57230 | 32425167 |
Depression | 35.18 | 21.14 | 25 | 31104 | 97035 | 32385362 |
Aspartate aminotransferase increased | 35.15 | 21.14 | 10 | 31119 | 66419 | 32415978 |
Insomnia | 34.88 | 21.14 | 27 | 31102 | 100321 | 32382076 |
Neuropathy peripheral | 34.88 | 21.14 | 15 | 31114 | 76967 | 32405430 |
Malignant neoplasm progression | 34.46 | 21.14 | 16 | 31113 | 78480 | 32403917 |
Procedural complication | 33.34 | 21.14 | 31 | 31098 | 4669 | 32477728 |
Psoriasis | 33.12 | 21.14 | 3 | 31126 | 46120 | 32436277 |
Staphylococcus test positive | 32.93 | 21.14 | 26 | 31103 | 3139 | 32479258 |
Malnutrition | 32.42 | 21.14 | 49 | 31080 | 12329 | 32470068 |
Eye inflammation | 32.06 | 21.14 | 21 | 31108 | 1892 | 32480505 |
Pneumonia | 32.03 | 21.14 | 497 | 30632 | 354755 | 32127642 |
Erythema | 32.01 | 21.14 | 20 | 31109 | 83085 | 32399312 |
Cataract operation complication | 32.00 | 21.14 | 10 | 31119 | 149 | 32482248 |
Tachycardia | 31.91 | 21.14 | 18 | 31111 | 79070 | 32403327 |
Rheumatoid arthritis | 31.71 | 21.14 | 3 | 31126 | 44541 | 32437856 |
Neutrophil count decreased | 31.47 | 21.14 | 4 | 31125 | 47135 | 32435262 |
Gait disturbance | 31.45 | 21.14 | 19 | 31110 | 80389 | 32402008 |
Asthma | 31.28 | 21.14 | 3 | 31126 | 44062 | 32438335 |
Discomfort | 31.01 | 21.14 | 55 | 31074 | 15800 | 32466597 |
Inappropriate schedule of product administration | 30.32 | 21.14 | 4 | 31125 | 45821 | 32436576 |
Peritoneal effluent leukocyte count increased | 30.04 | 21.14 | 7 | 31122 | 30 | 32482367 |
Blood creatine phosphokinase increased | 30.02 | 21.14 | 4 | 31125 | 45472 | 32436925 |
Pulmonary embolism | 29.72 | 21.14 | 22 | 31107 | 83637 | 32398760 |
Interstitial lung disease | 28.92 | 21.14 | 13 | 31116 | 64988 | 32417409 |
Diabetic vascular disorder | 28.69 | 21.14 | 8 | 31121 | 78 | 32482319 |
Fibrin | 28.68 | 21.14 | 7 | 31122 | 38 | 32482359 |
Peripheral vascular disorder | 28.53 | 21.14 | 30 | 31099 | 5242 | 32477155 |
Blood creatinine increased | 28.47 | 21.14 | 30 | 31099 | 96102 | 32386295 |
Corneal opacity | 28.46 | 21.14 | 13 | 31116 | 571 | 32481826 |
Diabetic ulcer | 28.45 | 21.14 | 9 | 31120 | 140 | 32482257 |
General physical health deterioration | 28.23 | 21.14 | 198 | 30931 | 115061 | 32367336 |
Infusion related reaction | 27.85 | 21.14 | 5 | 31124 | 45594 | 32436803 |
Cough | 27.74 | 21.14 | 57 | 31072 | 138760 | 32343637 |
Aggression | 27.14 | 21.14 | 3 | 31126 | 39386 | 32443011 |
Musculoskeletal stiffness | 27.03 | 21.14 | 3 | 31126 | 39261 | 32443136 |
Hydrocele | 26.93 | 21.14 | 20 | 31109 | 2204 | 32480193 |
Dyspnoea exertional | 26.76 | 21.14 | 3 | 31126 | 38958 | 32443439 |
Product container issue | 26.34 | 21.14 | 14 | 31115 | 856 | 32481541 |
Nosocomial infection | 26.28 | 21.14 | 16 | 31113 | 1269 | 32481128 |
Bacterial translocation | 26.22 | 21.14 | 10 | 31119 | 277 | 32482120 |
Drug intolerance | 25.77 | 21.14 | 8 | 31121 | 50227 | 32432170 |
Chest pain | 25.72 | 21.14 | 205 | 30924 | 123932 | 32358465 |
Road traffic accident | 25.06 | 21.14 | 53 | 31076 | 17328 | 32465069 |
Vitritis | 24.86 | 21.14 | 13 | 31116 | 769 | 32481628 |
Scrotal swelling | 24.85 | 21.14 | 16 | 31113 | 1400 | 32480997 |
International normalised ratio increased | 24.82 | 21.14 | 8 | 31121 | 49027 | 32433370 |
Corneal infiltrates | 24.46 | 21.14 | 9 | 31120 | 225 | 32482172 |
Product use issue | 24.36 | 21.14 | 10 | 31119 | 52767 | 32429630 |
Blood pressure abnormal | 24.25 | 21.14 | 33 | 31096 | 7547 | 32474850 |
Hallucination | 24.24 | 21.14 | 10 | 31119 | 52609 | 32429788 |
Foetal exposure during pregnancy | 24.22 | 21.14 | 5 | 31124 | 41296 | 32441101 |
Blood glucose decreased | 24.00 | 21.14 | 45 | 31084 | 13489 | 32468908 |
Post procedural infection | 23.73 | 21.14 | 26 | 31103 | 4759 | 32477638 |
Hepatic function abnormal | 23.26 | 21.14 | 7 | 31122 | 44833 | 32437564 |
Hospitalisation | 23.05 | 21.14 | 9 | 31120 | 48962 | 32433435 |
Paraesthesia | 22.95 | 21.14 | 14 | 31115 | 58930 | 32423467 |
Skin exfoliation | 22.66 | 21.14 | 64 | 31065 | 25093 | 32457304 |
Blood glucose false positive | 22.58 | 21.14 | 6 | 31123 | 48 | 32482349 |
Oxygen saturation decreased | 22.38 | 21.14 | 9 | 31120 | 48090 | 32434307 |
Blood bilirubin increased | 22.12 | 21.14 | 5 | 31124 | 38779 | 32443618 |
Pain | 21.73 | 21.14 | 99 | 31030 | 187457 | 32294940 |
Intestinal perforation | 21.65 | 21.14 | 34 | 31095 | 8841 | 32473556 |
Withdrawal of life support | 21.54 | 21.14 | 5 | 31124 | 21 | 32482376 |
Anterior chamber disorder | 21.49 | 21.14 | 7 | 31122 | 120 | 32482277 |
Coronary artery occlusion | 21.38 | 21.14 | 39 | 31090 | 11446 | 32470951 |
Stomatitis | 21.38 | 21.14 | 6 | 31123 | 40223 | 32442174 |
Tremor | 21.24 | 21.14 | 28 | 31101 | 81249 | 32401148 |
Aqueous fibrin | 21.21 | 21.14 | 6 | 31123 | 62 | 32482335 |
Intentional product use issue | 21.16 | 21.14 | 7 | 31122 | 42204 | 32440193 |
Source | Code | Description |
---|---|---|
ATC | A12CC01 | ALIMENTARY TRACT AND METABOLISM MINERAL SUPPLEMENTS OTHER MINERAL SUPPLEMENTS Magnesium |
ATC | B05XA11 | BLOOD AND BLOOD FORMING ORGANS BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS I.V. SOLUTION ADDITIVES Electrolyte solutions |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Hypomagnesemia | indication | 190855004 | |
Anuria | contraindication | 2472002 | DOID:2983 |
Hypocalcemia | contraindication | 5291005 | |
Classical phenylketonuria | contraindication | 7573000 | |
Poisoning by digitalis glycoside | contraindication | 12876009 | |
Hyperkalemia | contraindication | 14140009 | |
Complete atrioventricular block | contraindication | 27885002 | |
Sarcoidosis | contraindication | 31541009 | DOID:11335 |
End stage renal disease | contraindication | 46177005 | DOID:784 |
Humoral hypercalcemia of malignancy | contraindication | 47709007 | |
Heart disease | contraindication | 56265001 | DOID:114 |
Congenital myotonia, autosomal dominant form | contraindication | 57938005 | |
Acute nephropathy | contraindication | 58574008 | |
Diarrhea | contraindication | 62315008 | |
Hypercalcemia | contraindication | 66931009 | DOID:12678 |
Hypermagnesemia | contraindication | 66978005 | |
Ventricular fibrillation | contraindication | 71908006 | |
Hypercalciuria | contraindication | 71938000 | |
Hyperchloremia | contraindication | 74450001 | |
Third degree burn injury | contraindication | 80247002 | |
Oliguria | contraindication | 83128009 | |
Kidney disease | contraindication | 90708001 | DOID:557 |
Kidney stone | contraindication | 95570007 | |
Hyporeninemic hypoaldosteronism | contraindication | 236464008 | |
Familial hyperkalemic periodic paralysis | contraindication | 304737009 | DOID:14451 |
Azotemia | contraindication | 445009001 | |
Severe dehydration | contraindication | 450316000 |
None
Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Patent number | Patent expiration date | Patent use |
---|---|---|---|---|---|---|---|---|---|---|
0.21GM/100ML;2.8GM/100ML;9.07GM/100ML | NORMOCARB HF 25 | DIALYSIS SUPS | N021910 | July 26, 2006 | RX | SOLUTION | INJECTION | 7300674 | March 4, 2023 | USE AS REPLACEMENT SOLUTION, HEMOFILTRATION SOLUTION OR HEMODIAFILTRATION SOLUTION IN CONTINUOUS RENAL REPLACEMENT THERAPY |
Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Exclusivity date | Description |
---|---|---|---|---|---|---|---|---|---|
3.68GM/1000ML;3.05GM/1000ML;0.314GM/1000ML ;3.09GM/1000ML;6.34GM/1000ML;0.187GM/1000ML (5000ML) | PHOXILLUM BK 4/2.5 IN PLASTIC CONTAINER | BAXTER HLTHCARE CORP | N207026 | Jan. 13, 2015 | RX | INJECTABLE | INJECTION | Jan. 13, 2022 | AS A REPLACEMENT SOLUTION IN CONTINUOUS RENAL REPLACEMENT THERAPY (CRRT) AND IN CASE OF DRUG POISONING WHEN CRRT IS USED TO REMOVE DIALYZABLE SUBSTANCES |
N/A/1000ML;3.05GM/1000ML;0.314GM/1000ML;2.21GM/1000ML;6.95GM/1000ML;0.187GM/1000ML (5000ML) | PHOXILLUM B22K 4/0 IN PLASTIC CONTAINER | BAXTER HLTHCARE CORP | N207026 | Jan. 13, 2015 | RX | INJECTABLE | INJECTION | Jan. 13, 2022 | AS A REPLACEMENT SOLUTION IN CONTINUOUS RENAL REPLACEMENT THERAPY (CRRT) AND IN CASE OF DRUG POISONING WHEN CRRT IS USED TO REMOVE DIALYZABLE SUBSTANCES |
None
ID | Source |
---|---|
4018213 | VUID |
N0000146546 | NUI |
D04834 | KEGG_DRUG |
4018213 | VANDF |
C0024472 | UMLSCUI |
CHEBI:86345 | CHEBI |
CHEMBL2219642 | ChEMBL_ID |
CHEMBL3185229 | ChEMBL_ID |
D015636 | MESH_DESCRIPTOR_UI |
DB09407 | DRUGBANK_ID |
7791-18-6 | SECONDARY_CAS_RN |
02F3473H9O | UNII |
46835706 | PUBCHEM_CID |
6579 | RXNORM |
5007 | MMSL |
5009 | MMSL |
71973 | MMSL |
d03796 | MMSL |
000786 | NDDF |
45733002 | SNOMEDCT_US |
768454005 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
BSS | HUMAN PRESCRIPTION DRUG LABEL | 6 | 0065-0795 | SOLUTION | 0.30 mg | OPHTHALMIC | NDA | 9 sections |
BSS | HUMAN PRESCRIPTION DRUG LABEL | 6 | 0065-0795 | SOLUTION | 0.30 mg | OPHTHALMIC | NDA | 9 sections |
BSS | HUMAN PRESCRIPTION DRUG LABEL | 6 | 0065-1795 | SOLUTION | 0.30 mg | OPHTHALMIC | NDA | 9 sections |
HyperlyteCR | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0264-1943 | INJECTION, SOLUTION, CONCENTRATE | 0.51 g | INTRAVENOUS | UNAPPROVED DRUG OTHER | 18 sections |
HyperlyteCR | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0264-1943 | INJECTION, SOLUTION, CONCENTRATE | 0.51 g | INTRAVENOUS | UNAPPROVED DRUG OTHER | 18 sections |
Balanced Salt | HUMAN PRESCRIPTION DRUG LABEL | 6 | 0264-1945 | SOLUTION | 0.30 mg | IRRIGATION | ANDA | 11 sections |
Physiolyte | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0264-2205 | IRRIGANT | 0.03 g | IRRIGATION | NDA | 20 sections |
Physiolyte | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0264-2205 | IRRIGANT | 0.03 g | IRRIGATION | NDA | 20 sections |
Balanced Salt | HUMAN PRESCRIPTION DRUG LABEL | 6 | 0264-2514 | SOLUTION | 0.30 mg | IRRIGATION | ANDA | 11 sections |
Isolyte S | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0264-7703 | INJECTION, SOLUTION | 0.03 g | INTRAVENOUS | NDA | 19 sections |
Isolyte S | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0264-7703 | INJECTION, SOLUTION | 0.03 g | INTRAVENOUS | NDA | 19 sections |
Isolyte S pH 7.4 | HUMAN PRESCRIPTION DRUG LABEL | 7 | 0264-7707 | INJECTION, SOLUTION | 0.03 g | INTRAVENOUS | NDA | 24 sections |
Isolyte S pH 7.4 | HUMAN PRESCRIPTION DRUG LABEL | 7 | 0264-7707 | INJECTION, SOLUTION | 0.03 g | INTRAVENOUS | NDA | 24 sections |
Isolyte P in Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0264-7730 | INJECTION, SOLUTION | 0.03 g | INTRAVENOUS | NDA | 23 sections |
Isolyte P in Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0264-7730 | INJECTION, SOLUTION | 0.03 g | INTRAVENOUS | NDA | 23 sections |
Dextrose and Electrolyte No. 48 | HUMAN PRESCRIPTION DRUG LABEL | 6 | 0338-0143 | INJECTION | 31 mg | INTRAVENOUS | NDA | 19 sections |
Dextrose and Electrolyte No. 48 | HUMAN PRESCRIPTION DRUG LABEL | 6 | 0338-0143 | INJECTION | 31 mg | INTRAVENOUS | NDA | 19 sections |
Plasma-Lyte 148 | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0338-0179 | INJECTION, SOLUTION | 30 mg | INTRAVENOUS | NDA | 20 sections |
Plasma-Lyte 148 | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0338-0179 | INJECTION, SOLUTION | 30 mg | INTRAVENOUS | NDA | 20 sections |
CLINIMIX E | HUMAN PRESCRIPTION DRUG LABEL | 21 | 0338-0202 | INJECTION | 51 mg | INTRAVENOUS | NDA | 20 sections |
CLINIMIX E | HUMAN PRESCRIPTION DRUG LABEL | 21 | 0338-0202 | INJECTION | 51 mg | INTRAVENOUS | NDA | 20 sections |
CLINIMIX E | HUMAN PRESCRIPTION DRUG LABEL | 21 | 0338-0206 | INJECTION | 51 mg | INTRAVENOUS | NDA | 20 sections |
CLINIMIX E | HUMAN PRESCRIPTION DRUG LABEL | 21 | 0338-0206 | INJECTION | 51 mg | INTRAVENOUS | NDA | 20 sections |
CLINIMIX E | HUMAN PRESCRIPTION DRUG LABEL | 21 | 0338-0210 | INJECTION | 51 mg | INTRAVENOUS | NDA | 20 sections |
CLINIMIX E | HUMAN PRESCRIPTION DRUG LABEL | 21 | 0338-0210 | INJECTION | 51 mg | INTRAVENOUS | NDA | 20 sections |
CLINIMIX E | HUMAN PRESCRIPTION DRUG LABEL | 21 | 0338-0214 | INJECTION | 51 mg | INTRAVENOUS | NDA | 20 sections |
CLINIMIX E | HUMAN PRESCRIPTION DRUG LABEL | 21 | 0338-0214 | INJECTION | 51 mg | INTRAVENOUS | NDA | 20 sections |
Plasma-Lyte A | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0338-0221 | INJECTION, SOLUTION | 30 mg | INTRAVENOUS | NDA | 19 sections |
Plasma-Lyte A | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0338-0221 | INJECTION, SOLUTION | 30 mg | INTRAVENOUS | NDA | 19 sections |
Cardioplegic | HUMAN PRESCRIPTION DRUG LABEL | 4 | 0338-0341 | SOLUTION | 325.30 mg | INTRA-ARTERIAL | ANDA | 15 sections |