magnesium aspartate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4517	18962-61-3

Description:

Molecule

Description

Synonyms:

magnesium aspartate
Aspartic Acid, Magnesium (2:1) Salt
magnesium hydroaspartate

Molecular weight: 288.50
Formula: C8H12MgN2O8
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA:
ALOGS:
ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Listless	81.70	35.10	19	2106	2841	63484056
Reduced facial expression	72.03	35.10	16	2109	1950	63484947
Apathy	60.56	35.10	19	2106	8775	63478122
Reflexes abnormal	57.02	35.10	11	2114	670	63486227
Restlessness	53.73	35.10	24	2101	29429	63457468
Head discomfort	52.69	35.10	19	2106	13396	63473501
Hypokalaemia	47.25	35.10	34	2091	103770	63383127
Affect lability	44.56	35.10	16	2109	11135	63475762
Immobile	41.58	35.10	13	2112	5930	63480967
Urinary retention	40.73	35.10	20	2105	30281	63456616
Delirium	38.82	35.10	23	2102	50518	63436379
Foreign body	38.61	35.10	10	2115	2328	63484569
Liver function test increased	36.34	35.10	19	2106	32792	63454105

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Infective exacerbation of chronic obstructive airways disease	79.03	33.61	18	1548	1833	34953532
Fractional exhaled nitric oxide increased	48.76	33.61	11	1555	1071	34954294
Hypomagnesaemia	47.59	33.61	22	1544	21829	34933536
Nerve degeneration	46.07	33.61	8	1558	200	34955165
Plantar fasciitis	41.43	33.61	11	1555	2105	34953260
Sensation of foreign body	38.44	33.61	11	1555	2772	34952593
Myoglobin blood increased	37.54	33.61	11	1555	3012	34952353
Meningitis cryptococcal	35.45	33.61	10	1556	2394	34952971

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Infective exacerbation of chronic obstructive airways disease	72.47	27.79	18	3398	2766	79738206
Listless	71.35	27.79	19	3397	3842	79737130
Reduced facial expression	62.65	27.79	16	3400	2749	79738223
Reflexes abnormal	50.73	27.79	11	3405	932	79740040
Apathy	48.71	27.79	19	3397	12958	79728014
Hypomagnesaemia	47.87	27.79	28	3388	46883	79694089
Head discomfort	46.66	27.79	19	3397	14483	79726489
Nerve degeneration	43.74	27.79	8	3408	283	79740689
Affect lability	40.55	27.79	16	3400	11243	79729729
Restlessness	37.80	27.79	24	3392	46468	79694504
Immobile	36.38	27.79	13	3403	6960	79734012
Hypokalaemia	35.58	27.79	37	3379	144003	79596969
Foreign body	34.04	27.79	10	3406	2884	79738088
Meningitis cryptococcal	32.15	27.79	10	3406	3496	79737476
Hyponatraemia	30.82	27.79	38	3378	177810	79563162
Pelvic fracture	29.32	27.79	13	3403	12191	79728781
Liver function test increased	28.57	27.79	19	3397	39754	79701218
Pyrexia	28.41	27.79	78	3338	678631	79062341
Renal neoplasm	28.36	27.79	8	3408	2000	79738972

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	A12CC05	ALIMENTARY TRACT AND METABOLISM MINERAL SUPPLEMENTS OTHER MINERAL SUPPLEMENTS Magnesium

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Constipation	indication	14760008	DOID:2089
Hypokalemia	indication	43339004
Indigestion	indication	162031009
Hypomagnesemia	indication	190855004
Incomplete passage of stool	indication	249515001
Hypokalemia Prevention	indication
Hyperkalemia	contraindication	14140009
Complete atrioventricular block	contraindication	27885002
Gastrointestinal ulcer	contraindication	40845000
Congenital myotonia, autosomal dominant form	contraindication	57938005
Acute nephropathy	contraindication	58574008
Diarrhea	contraindication	62315008
Kidney disease	contraindication	90708001	DOID:557
Gastrointestinal obstruction	contraindication	126765001
Gastroparesis	contraindication	235675006
Chronic diarrhea	contraindication	236071009
Hyporeninemic hypoaldosteronism	contraindication	236464008
Familial hyperkalemic periodic paralysis	contraindication	304737009	DOID:14451
Severe dehydration	contraindication	450316000

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
4030488	VUID
N0000182443	NUI
4030488	VANDF
CHEMBL2109228	ChEMBL_ID
DB13359	DRUGBANK_ID
R17X820ROL	UNII
142131	RXNORM
d05397	MMSL
003851	NDDF
421128005	SNOMEDCT_US
421363009	SNOMEDCT_US
C0543448	UMLSCUI
D001224	MESH_DESCRIPTOR_UI
87869	PUBCHEM_CID
7018-07-7	SECONDARY_CAS_RN

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Dermamed Nutrition for troubled skin	HUMAN OTC DRUG LABEL	7	69711-687	CAPSULE, GELATIN COATED	50 mg	ORAL	OTC monograph not final	10 sections