tocofersolan 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
4280 59-02-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • tocophersolan
  • .ALPHA.-TOCOPHEROL, D-
  • alpha-tocopherol
  • alpha-D-Tocopherol
  • syntopherol
  • ALPHA-TOCOPHEROL, D-
  • .ALPHA.-TOCOPHEROL
  • d-alpha-tocopherol
  • alpha-tocopherol, dl-
  • .Alpha.-tocopherol, DL-
  • tocofersolan
  • vedrop
A natural tocopherol and one of the most potent antioxidant tocopherols. It exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus. It has four methyl groups on the 6-chromanol nucleus. The natural d form of alpha-tocopherol is more active than its synthetic dl-alpha-tocopherol racemic mixture.
  • Molecular weight: 430.72
  • Formula: C29H50O2
  • CLOGP: 12
  • LIPINSKI: 1
  • HAC: 2
  • HDO: 1
  • TPSA: 29.46
  • ALOGS: -7.79
  • ROTB: 12
  • Status: OFP
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

DoseUnitRoute
0.20 g O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,ACVRL1,AKT2,AKT3,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GSK3B,IKBKB,ITK,JAK2,JAK3,MAP2K6,MAP3K21,MAP3K7,MAPK10,MAPK7,MAPK9,MAPKAPK2,MET,MTOR,NTRK2,PDK2,PDK4,PDPK1,PIK3CA,PIK3CB,PIK3CD,PIK3CG,PIM2,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ZAP70 53
kinase-selectivity-class AXL,BRAF,EIF2AK3,EPHB4,GRK2,MAP2K6,STK33,TEK 8
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Macular degeneration 412.62 11.71 234 37567 37736 90552910
Chronic sinusitis 176.78 11.71 115 37686 23687 90566959
Electric shock 150.26 11.71 47 37754 1675 90588971
Paraesthesia oral 142.93 11.71 113 37688 31546 90559100
Vaginal flatulence 129.48 11.71 75 37726 12563 90578083
Muscle spasticity 128.02 11.71 111 37690 35211 90555435
Procedural pain 127.35 11.71 108 37693 33252 90557394
Proctitis 118.91 11.71 76 37725 15183 90575463
Female genital tract fistula 112.67 11.71 78 37723 17790 90572856
Radiculopathy 107.90 11.71 77 37724 18428 90572218
Back pain 107.23 11.71 333 37468 316842 90273804
Vaginal discharge 106.66 11.71 78 37723 19386 90571260
Hand deformity 106.08 11.71 4 37797 296358 90294288
Intervertebral discitis 106.07 11.71 47 37754 4473 90586173
Therapy cessation 100.12 11.71 98 37703 36263 90554383
Post-traumatic stress disorder 96.15 11.71 50 37751 6778 90583868
Weight decreased 96.08 11.71 362 37439 379548 90211098
Glossodynia 95.90 11.71 11 37790 321768 90268878
Post cholecystectomy syndrome 93.71 11.71 28 37773 853 90589793
Pemphigus 92.98 11.71 13 37788 326851 90263795
Body temperature increased 90.06 11.71 102 37699 44608 90546038
Blood immunoglobulin A increased 87.33 11.71 29 37772 1254 90589392
Ear pain 85.93 11.71 113 37688 57589 90533057
Systemic lupus erythematosus 84.89 11.71 23 37778 361873 90228773
Vitamin B12 increased 84.67 11.71 31 37770 1795 90588851
Temperature intolerance 84.15 11.71 56 37745 11974 90578672
Duodenal ulcer perforation 79.13 11.71 3 37798 221285 90369361
Granulocyte count increased 78.46 11.71 28 37773 1506 90589140
Wound 77.47 11.71 16 37785 302964 90287682
Demyelination 77.31 11.71 46 37755 8094 90582552
General physical health deterioration 77.08 11.71 26 37775 355089 90235557
Maternal exposure during pregnancy 75.35 11.71 28 37773 360035 90230611
Oral candidiasis 75.03 11.71 83 37718 35372 90555274
Glomerular filtration rate increased 73.92 11.71 29 37772 2031 90588615
Rheumatoid factor increased 72.88 11.71 30 37771 2381 90588265
Pneumonia aspiration 68.56 11.71 85 37716 40855 90549791
Haematochezia 68.13 11.71 113 37688 70800 90519846
Aspartate aminotransferase 67.80 11.71 21 37780 724 90589922
Multiple sclerosis 67.41 11.71 70 37731 27770 90562876
Constipation 65.75 11.71 261 37540 280134 90310512
Pericarditis 63.65 11.71 17 37784 270134 90320512
Hernia 62.51 11.71 50 37751 14181 90576465
Progressive multifocal leukoencephalopathy 62.45 11.71 52 37749 15603 90575043
Toxicity to various agents 60.86 11.71 22 37779 287824 90302822
Dry eye 60.67 11.71 96 37705 57835 90532811
Anti-cyclic citrullinated peptide antibody positive 59.37 11.71 13 37788 236420 90354226
Rheumatoid factor positive 59.14 11.71 3 37798 171647 90418999
Blood uric acid increased 59.10 11.71 38 37763 7666 90582980
Respiratory disorder 56.61 11.71 99 37702 64717 90525929
Glaucoma 55.38 11.71 55 37746 20700 90569946
Presbyacusis 53.80 11.71 26 37775 3016 90587630
Throat clearing 53.68 11.71 28 37773 3819 90586827
Dactylitis 53.50 11.71 28 37773 3845 90586801
Diarrhoea 53.43 11.71 612 37189 938578 89652068
Joint noise 53.14 11.71 31 37770 5259 90585387
Exposure during pregnancy 50.76 11.71 18 37783 238392 90352254
Helicobacter infection 50.26 11.71 16 37785 226834 90363812
Pleural fibrosis 49.68 11.71 26 37775 3570 90587076
Pleural thickening 49.24 11.71 25 37776 3223 90587423
Frequent bowel movements 48.47 11.71 86 37715 56849 90533797
Depressed mood 48.19 11.71 80 37721 50142 90540504
Blood magnesium increased 48.11 11.71 25 37776 3383 90587263
Coordination abnormal 46.92 11.71 51 37750 21305 90569341
Liver injury 45.71 11.71 8 37793 170559 90420087
Hepatic necrosis 45.10 11.71 30 37771 6408 90584238
Spinal disorder 44.95 11.71 38 37763 11641 90579005
Blood immunoglobulin M increased 44.65 11.71 18 37783 1354 90589292
Headache 44.52 11.71 552 37249 862194 89728452
Peripheral swelling 43.45 11.71 308 37493 412798 90177848
Eye disorder 42.89 11.71 55 37746 27335 90563311
Colitis ulcerative 42.53 11.71 84 37717 60182 90530464
Blood test abnormal 42.52 11.71 48 37753 20904 90569742
Rheumatic disorder 42.46 11.71 23 37778 3385 90587261
Blood pressure systolic decreased 41.64 11.71 33 37768 9237 90581409
Balance disorder 41.49 11.71 111 37690 96969 90493677
Vitamin B12 deficiency 41.01 11.71 30 37771 7456 90583190
Vitamin D deficiency 40.46 11.71 43 37758 17513 90573133
Blood immunoglobulin A decreased 40.37 11.71 18 37783 1738 90588908
Injury 40.17 11.71 16 37785 197333 90393313
Neuropathy peripheral 39.17 11.71 136 37665 136834 90453812
Cataract operation 39.08 11.71 27 37774 6136 90584510
Colitis 38.38 11.71 88 37713 69854 90520792
Discomfort 38.05 11.71 35 37766 274300 90316346
Throat irritation 36.96 11.71 70 37731 48625 90542021
Deafness neurosensory 36.54 11.71 27 37774 6814 90583832
Insomnia 36.43 11.71 251 37550 333223 90257423
Product dose omission issue 36.39 11.71 227 37574 291460 90299186
Folliculitis 36.30 11.71 20 37781 204333 90386313
Epigastric discomfort 36.28 11.71 28 37773 7540 90583106
Confusional state 35.43 11.71 67 37734 386138 90204508
Ulcer 35.12 11.71 55 37746 32827 90557819
Cholecystitis acute 34.97 11.71 30 37771 9374 90581272
Rectal haemorrhage 34.75 11.71 94 37707 82650 90507996
Multiple allergies 34.73 11.71 37 37764 15109 90575537
Infective pulmonary exacerbation of cystic fibrosis 34.63 11.71 31 37770 10248 90580398
Red blood cell count decreased 34.40 11.71 66 37735 46285 90544361
Blood immunoglobulin G increased 34.11 11.71 19 37782 2953 90587693
Abdominal discomfort 33.95 11.71 95 37706 477233 90113413
Hepatic enzyme abnormal 33.88 11.71 27 37774 7615 90583031
Incorrect route of product administration 33.85 11.71 69 37732 50557 90540089
Monocyte count increased 33.78 11.71 29 37772 9068 90581578
Bone cyst 32.30 11.71 17 37784 2361 90588285
Synovitis 32.22 11.71 55 37746 329697 90260949
Hepatic encephalopathy 32.21 11.71 34 37767 13738 90576908
White blood cell count decreased 31.73 11.71 146 37655 166963 90423683
Monoclonal immunoglobulin present 31.19 11.71 16 37785 2108 90588538
Dyspepsia 31.12 11.71 164 37637 197996 90392650
Abdominal pain upper 30.95 11.71 241 37560 332433 90258213
Miosis 30.76 11.71 28 37773 9456 90581190
Gastrooesophageal reflux disease 30.61 11.71 144 37657 166193 90424453
Glycosylated haemoglobin increased 30.48 11.71 35 37766 15527 90575119
Facet joint syndrome 30.21 11.71 3 37798 98386 90492260
Somnolence 30.11 11.71 169 37632 208915 90381731
Osteopenia 29.62 11.71 42 37759 22960 90567686
Adrenal insufficiency 29.16 11.71 48 37753 29873 90560773
Wheezing 28.92 11.71 34 37767 238046 90352600
Body height decreased 28.84 11.71 30 37771 11919 90578727
Cyst 28.71 11.71 35 37766 16526 90574120
Intentional overdose 28.45 11.71 3 37798 93831 90496815
Pain 28.28 11.71 577 37224 995764 89594882
Blood alkaline phosphatase increased 28.06 11.71 62 37739 48017 90542629
Swelling 27.90 11.71 86 37715 418972 90171674
Aspartate aminotransferase abnormal 27.87 11.71 16 37785 2633 90588013
Coma 27.05 11.71 79 37722 72553 90518093
White blood cells urine positive 26.78 11.71 22 37779 6476 90584170
Fibromyalgia 26.65 11.71 28 37773 206241 90384405
Cataract 26.45 11.71 78 37723 72014 90518632
Asthenia 26.36 11.71 339 37462 533412 90057234
Herpes zoster 26.21 11.71 93 37708 94551 90496095
Blood glucose decreased 26.16 11.71 40 37761 23389 90567257
Completed suicide 26.04 11.71 14 37787 145044 90445602
Febrile neutropenia 26.01 11.71 17 37784 158332 90432314
Low turnover osteopathy 25.62 11.71 18 37783 4200 90586446
Night sweats 25.56 11.71 114 37687 128652 90461994
Osteosclerosis 25.23 11.71 18 37783 4302 90586344
Acute kidney injury 24.87 11.71 61 37740 320326 90270320
Fatigue 24.59 11.71 642 37159 1153381 89437265
Overdose 24.48 11.71 18 37783 157691 90432955
Lip dry 24.44 11.71 6 37795 100949 90489697
Epilepsy 23.99 11.71 3 37798 82203 90508443
Blood pressure increased 23.65 11.71 152 37649 197065 90393581
Pulmonary fibrosis 23.07 11.71 8 37793 107495 90483151
Sinusitis 22.82 11.71 231 37570 342857 90247789
Live birth 22.81 11.71 3 37798 79104 90511542
Muscle injury 22.79 11.71 24 37777 176630 90414016
Drug interaction 22.76 11.71 51 37750 276402 90314244
Irritable bowel syndrome 22.74 11.71 32 37769 207416 90383230
Nasal congestion 22.27 11.71 81 37720 83333 90507313
Drug intolerance 21.94 11.71 104 37697 447487 90143159
Carbuncle 21.62 11.71 11 37790 1425 90589221
Prescribed overdose 21.41 11.71 7 37794 97618 90493028
Impaired healing 21.13 11.71 41 37760 234158 90356488
Wound infection 21.04 11.71 9 37792 106393 90484253
Blister 21.02 11.71 47 37754 254951 90335695
Pain in extremity 20.91 11.71 283 37518 450246 90140400
Dermatitis atopic 20.68 11.71 36 37765 23436 90567210
Delusional disorder, persecutory type 20.62 11.71 7 37794 324 90590322
Cardiac arrest 20.55 11.71 9 37792 104926 90485720
Breast cancer stage III 20.47 11.71 5 37796 84442 90506204
Blood pressure fluctuation 20.47 11.71 58 37743 52355 90538291
Nausea 20.35 11.71 606 37195 1109710 89480936
Bronchitis 20.30 11.71 121 37680 152806 90437840
Alanine aminotransferase increased 20.00 11.71 100 37701 118238 90472408
Pruritus 20.00 11.71 327 37474 541198 90049448
Treatment failure 19.77 11.71 63 37738 303865 90286781
Hepatitis 19.66 11.71 3 37798 70736 90519910
Cognitive disorder 19.04 11.71 68 37733 69339 90521307
Blood urea increased 18.63 11.71 40 37761 30373 90560273
Colitis microscopic 18.41 11.71 23 37778 11136 90579510
Sleep disorder due to general medical condition, insomnia type 18.33 11.71 16 37785 128678 90461968
Therapy non-responder 18.29 11.71 18 37783 136686 90453960
Type 2 diabetes mellitus 17.97 11.71 36 37765 203208 90387438
Multiple fractures 17.88 11.71 21 37780 9541 90581105
Diverticulitis 17.64 11.71 50 37751 45137 90545509
Neutrophil count increased 17.42 11.71 30 37771 19360 90571286
Skin reaction 17.06 11.71 29 37772 18524 90572122
Thrombocytopenia 16.77 11.71 39 37762 208686 90381960
Dry skin 16.74 11.71 77 37724 87996 90502650
Spinal epidural haematoma 16.61 11.71 9 37792 1325 90589321
Obesity 16.43 11.71 12 37789 105495 90485151
Overweight 16.34 11.71 16 37785 5918 90584728
Delirium 16.08 11.71 12 37789 104347 90486299
Autoimmune disorder 15.97 11.71 6 37795 76738 90513908
Pancytopenia 15.89 11.71 16 37785 120247 90470399
Interstitial lung disease 15.86 11.71 6 37795 76399 90514247
Joint range of motion decreased 15.80 11.71 20 37781 135623 90455023
Bursitis 15.77 11.71 19 37782 131635 90459011
Intentional product use issue 15.51 11.71 43 37758 216849 90373797
Arthralgia 15.34 11.71 429 37372 778093 89812553
Peripheral venous disease 15.21 11.71 8 37793 83913 90506733
Bradycardia 15.18 11.71 8 37793 83839 90506807
Cardiac failure 15.13 11.71 14 37787 109482 90481164
Grip strength decreased 15.11 11.71 10 37791 92566 90498080
Therapeutic product effect incomplete 15.09 11.71 135 37666 193761 90396885
Hypercholesterolaemia 15.04 11.71 12 37789 100880 90489766
Dysphagia 15.00 11.71 89 37712 112189 90478457
Mucosal inflammation 14.80 11.71 3 37798 57622 90533024
Blood potassium increased 14.73 11.71 29 37772 20720 90569926
Gait inability 14.68 11.71 24 37777 146432 90444214
Bone hypertrophy 14.64 11.71 6 37795 471 90590175
Lung disorder 14.62 11.71 25 37776 149858 90440788
Hypothalamo-pituitary disorder 14.59 11.71 10 37791 2242 90588404
Malignant neoplasm progression 14.37 11.71 14 37787 106856 90483790
Dislocation of vertebra 14.19 11.71 3 37798 55965 90534681
Multiple sclerosis relapse 14.14 11.71 51 37750 52254 90538392
Erythema 14.12 11.71 152 37649 229094 90361552
Cough 14.05 11.71 224 37577 368738 90221908
Medication error 14.02 11.71 9 37792 84643 90506003
Septic shock 13.86 11.71 9 37792 84151 90506495
Neutropenia 13.67 11.71 48 37753 224856 90365790
C-reactive protein abnormal 13.62 11.71 20 37781 127409 90463237
Urticaria 13.50 11.71 194 37607 312540 90278106
Skin irritation 13.49 11.71 22 37779 13581 90577065
Blood creatinine increased 13.31 11.71 80 37721 101306 90489340
Inflammation 13.08 11.71 35 37766 178557 90412089
Lower limb fracture 12.81 11.71 10 37791 85003 90505643
Flatulence 12.63 11.71 42 37759 41325 90549321
Intramedullary rod insertion 12.57 11.71 9 37792 2163 90588483
Deformity 12.50 11.71 20 37781 12150 90578496
Anaemia postoperative 12.42 11.71 9 37792 2204 90588442
Underdose 12.40 11.71 50 37751 53967 90536679
Skin lesion 12.37 11.71 39 37762 37326 90553320
Ill-defined disorder 12.24 11.71 38 37763 184853 90405793
Tachycardia 12.24 11.71 30 37771 157643 90433003
Contraindicated product administered 12.08 11.71 81 37720 320058 90270588
Ageusia 12.06 11.71 23 37778 16053 90574593
Angioedema 12.03 11.71 6 37795 64870 90525776
Sciatic nerve injury 11.93 11.71 6 37795 758 90589888
Stress 11.84 11.71 66 37735 81329 90509317
Hepatic enzyme increased 11.82 11.71 95 37706 360641 90230005
Hepatotoxicity 11.80 11.71 44 37757 45798 90544848

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Appendicolith 229.30 16.97 107 15245 13349 42592634
Blood phosphorus increased 217.77 16.97 101 15251 12424 42593559
Appendicitis 191.59 16.97 109 15243 20504 42585479
Ventricular fibrillation 151.34 16.97 108 15244 30015 42575968
Blood uric acid increased 143.88 16.97 82 15270 15465 42590518
Myasthenia gravis 143.69 16.97 83 15269 16054 42589929
Blood cholesterol increased 134.60 16.97 96 15256 26645 42579338
Stress 134.60 16.97 118 15234 44094 42561889
Cardiogenic shock 128.78 16.97 105 15247 35535 42570448
Dry mouth 128.59 16.97 110 15242 39769 42566214
Hyperphosphataemia 121.43 16.97 69 15283 12935 42593048
Analgesic therapy 108.38 16.97 51 15301 6473 42599510
Ascites 107.99 16.97 117 15235 56561 42549422
Neuralgia 104.27 16.97 81 15271 25566 42580417
Drug therapy 103.30 16.97 49 15303 6331 42599652
Abdominal distension 103 16.97 128 15224 71607 42534376
Sleep disorder therapy 102.68 16.97 50 15302 6844 42599139
Hypophosphataemia 102.65 16.97 74 15278 20871 42585112
Iron deficiency 101.41 16.97 58 15294 11003 42594980
Bacterial infection 90.04 16.97 77 15275 27802 42578181
Fractional exhaled nitric oxide increased 81.18 16.97 28 15324 1581 42604402
Infective pulmonary exacerbation of cystic fibrosis 79.82 16.97 44 15308 7774 42598209
Incorrect route of product administration 72.17 16.97 64 15288 24241 42581742
Thrombosis 69.05 16.97 103 15249 68408 42537575
Sleep disorder 67.67 16.97 85 15267 48010 42557973
Drug intolerance 67.30 16.97 111 15241 80313 42525670
Constipation 66.09 16.97 166 15186 162125 42443858
Hyponatraemia 64.29 16.97 124 15228 101338 42504645
Plantar fasciitis 63.62 16.97 28 15324 3042 42602941
Sensation of foreign body 62.34 16.97 29 15323 3584 42602399
Multiple organ dysfunction syndrome 61.98 16.97 119 15233 96916 42509067
Swelling 60.35 16.97 86 15266 54799 42551184
Myoglobin blood increased 58.75 16.97 28 15324 3654 42602329
Activated partial thromboplastin time prolonged 55.61 16.97 46 15306 15857 42590126
Diabetes mellitus 54.43 16.97 86 15266 60001 42545982
Secretion discharge 54.28 16.97 34 15318 7601 42598382
Anticoagulant therapy 50.39 16.97 27 15325 4508 42601475
Antacid therapy 49.40 16.97 27 15325 4690 42601293
Chronic obstructive pulmonary disease 46.05 16.97 82 15270 63032 42542951
Brain natriuretic peptide increased 45.26 16.97 29 15323 6741 42599242
Somnolence 44.07 16.97 131 15221 140974 42465009
Toxicity to various agents 43.85 16.97 14 15338 229122 42376861
Intentional product misuse 43.34 16.97 79 15273 61821 42544162
Bacteroides infection 42.27 16.97 20 15332 2567 42603416
Drug interaction 41.90 16.97 22 15330 266977 42339006
Acute kidney injury 40.13 16.97 44 15308 367293 42238690
Abdominal pain 39.36 16.97 154 15198 190317 42415666
Aortic stenosis 38.55 16.97 29 15323 8716 42597267
End stage renal disease 38.37 16.97 38 15314 16520 42589463
Rubber sensitivity 36.62 16.97 11 15341 397 42605586
Gout 35.39 16.97 47 15305 28008 42577975
Nasopharyngitis 34.20 16.97 86 15266 83910 42522073
General physical health deterioration 33.46 16.97 125 15227 151121 42454862
Chest discomfort 33.43 16.97 72 15280 63544 42542439
Ulcer 33.13 16.97 35 15317 16406 42589577
Drug hypersensitivity 28.86 16.97 90 15262 99299 42506684
Hyperlipidaemia 28.62 16.97 37 15315 21479 42584504
Therapy cessation 28.51 16.97 36 15316 20414 42585569
Blood calcium increased 26.56 16.97 23 15329 8431 42597552
Dysphonia 26.13 16.97 41 15311 28409 42577574
Troponin increased 25.70 16.97 33 15319 19029 42586954
Cardiac disorder 25.26 16.97 55 15297 48877 42557106
Condition aggravated 24.98 16.97 170 15182 260584 42345399
Muscle spasms 24.14 16.97 77 15275 85967 42520016
Febrile neutropenia 24.05 16.97 19 15333 185684 42420299
Neutropenia 23.88 16.97 22 15330 199409 42406574
Sepsis 23.46 16.97 137 15215 199197 42406786
Exostosis 23.33 16.97 18 15334 5613 42600370
Coronary artery disease 22.90 16.97 56 15296 53664 42552319
Hypotension 22.82 16.97 36 15316 257595 42348388
Cataract nuclear 22.30 16.97 9 15343 788 42605195
Completed suicide 22.13 16.97 4 15348 96461 42509522
Nausea 22.12 16.97 229 15123 396570 42209413
Total lung capacity decreased 20.72 16.97 14 15338 3556 42602427
Blood test abnormal 20.06 16.97 24 15328 12882 42593101
Bronchopulmonary aspergillosis allergic 19.72 16.97 15 15337 4583 42601400
Obstructive airways disorder 19.12 16.97 33 15319 24726 42581257
Rhonchi 19.10 16.97 11 15341 2112 42603871
Pulmonary embolism 18.72 16.97 89 15263 119523 42486460
Interstitial lung disease 18.55 16.97 3 15349 78459 42527524
Product dose omission issue 18.08 16.97 106 15246 154259 42451724
Pancytopenia 18.00 16.97 10 15342 117733 42488250
Product administered at inappropriate site 17.62 16.97 12 15340 3086 42602897

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Appendicolith 223.19 12.52 111 44617 14144 110530427
Blood uric acid increased 201.02 12.52 119 44609 21410 110523161
Blood phosphorus increased 194.87 12.52 106 44622 16234 110528337
Macular degeneration 179.74 12.52 111 44617 21548 110523023
Chronic sinusitis 169.64 12.52 113 44615 24971 110519600
Appendicitis 156.72 12.52 113 44615 28351 110516220
Electric shock 148.91 12.52 47 44681 1781 110542790
Vaginal flatulence 134.41 12.52 75 44653 12069 110532502
Paraesthesia oral 131.43 12.52 109 44619 33562 110511009
Myasthenia gravis 129.06 12.52 90 44638 21421 110523150
Procedural pain 122.20 12.52 107 44621 35458 110509113
Muscle spasticity 121.29 12.52 107 44621 35808 110508763
Proctitis 121.12 12.52 79 44649 16848 110527723
Female genital tract fistula 120.42 12.52 78 44650 16441 110528130
Ventricular fibrillation 117.90 12.52 112 44616 41201 110503370
Hyperphosphataemia 113.67 12.52 75 44653 16306 110528265
Vaginal discharge 112.31 12.52 77 44651 17831 110526740
Therapy cessation 111.94 12.52 113 44615 44744 110499827
Analgesic therapy 111.89 12.52 56 44672 7228 110537343
Radiculopathy 109.27 12.52 78 44650 19258 110525313
Constipation 108.78 12.52 355 44373 357431 110187140
Sleep disorder therapy 107.64 12.52 55 44673 7416 110537155
Toxicity to various agents 106.75 12.52 31 44697 480524 110064047
Drug therapy 105.99 12.52 54 44674 7237 110537334
Incorrect route of product administration 104.10 12.52 129 44599 63932 110480639
Stress 101.17 12.52 165 44563 105183 110439388
Post-traumatic stress disorder 99.23 12.52 50 44678 6546 110538025
Intervertebral discitis 96.49 12.52 50 44678 6940 110537631
Post cholecystectomy syndrome 95.49 12.52 28 44700 824 110543747
Iron deficiency 87.47 12.52 67 44661 18409 110526162
Infective pulmonary exacerbation of cystic fibrosis 86.74 12.52 61 44667 14710 110529861
Vitamin B12 increased 85.66 12.52 32 44696 2023 110542548
Hypophosphataemia 83.54 12.52 84 44644 33098 110511473
Ear pain 82.99 12.52 105 44623 53121 110491450
Cardiogenic shock 82.96 12.52 109 44619 57229 110487342
Temperature intolerance 80.50 12.52 57 44671 13893 110530678
Back pain 78.92 12.52 328 44400 370668 110173903
Weight decreased 78.76 12.52 386 44342 467671 110076900
Neuralgia 77.76 12.52 97 44631 48381 110496190
Glomerular filtration rate increased 76.41 12.52 29 44699 1916 110542655
Blood immunoglobulin A increased 74.93 12.52 27 44701 1541 110543030
Acute kidney injury 72.88 12.52 90 44638 635340 109909231
Rheumatoid factor increased 72.67 12.52 30 44698 2475 110542096
Demyelination 72.38 12.52 46 44682 9383 110535188
Granulocyte count increased 72.29 12.52 28 44700 1955 110542616
Hand deformity 72.07 12.52 4 44724 218502 110326069
Ascites 70.37 12.52 131 44597 92677 110451894
Ulcer 70.32 12.52 87 44641 43029 110501542
Body temperature increased 70.03 12.52 98 44630 54615 110489956
Aspartate aminotransferase 67.01 12.52 22 44706 947 110543624
Blood test abnormal 65.93 12.52 69 44659 28485 110516086
Dry eye 65.63 12.52 96 44632 55697 110488874
Drug interaction 64.86 12.52 64 44664 500119 110044452
Oral candidiasis 64.61 12.52 85 44643 44675 110499896
Abdominal distension 61.69 12.52 183 44545 174920 110369651
Bacterial infection 61.22 12.52 84 44644 45952 110498619
Multiple sclerosis 60.95 12.52 63 44665 25635 110518936
Somnolence 60.12 12.52 259 44469 297190 110247381
Respiratory disorder 58.22 12.52 104 44624 71278 110473293
Maternal exposure during pregnancy 57.37 12.52 16 44712 254867 110289704
Anticoagulant therapy 56.32 12.52 32 44696 5329 110539242
Thrombosis 56.11 12.52 131 44597 108531 110436040
Antacid therapy 55.64 12.52 32 44696 5452 110539119
Presbyacusis 53.34 12.52 25 44703 2794 110541777
Dry mouth 53.30 12.52 190 44538 199758 110344813
Glaucoma 53.04 12.52 55 44673 22462 110522109
Dactylitis 52.60 12.52 28 44700 4105 110540466
Joint noise 52.15 12.52 30 44698 5113 110539458
Glossodynia 51.73 12.52 13 44715 221991 110322580
Hepatic necrosis 51.45 12.52 38 44690 9884 110534687
Throat clearing 51.35 12.52 28 44700 4305 110540266
Completed suicide 51.32 12.52 17 44711 242364 110302207
Duodenal ulcer perforation 51.02 12.52 6 44722 177694 110366877
Febrile neutropenia 50.46 12.52 33 44695 316734 110227837
Peripheral swelling 50.23 12.52 307 44421 403727 110140844
Pemphigus 49.16 12.52 13 44715 214557 110330014
Systemic lupus erythematosus 48.58 12.52 21 44707 254317 110290254
Progressive multifocal leukoencephalopathy 48.37 12.52 55 44673 24901 110519670
Diabetes mellitus 48.27 12.52 117 44611 99264 110445307
Hernia 46.59 12.52 48 44680 19452 110525119
Nausea 46.20 12.52 728 44000 1234962 109309609
Blood magnesium increased 46.13 12.52 25 44703 3798 110540773
Pleural thickening 46.02 12.52 24 44704 3375 110541196
Pain 44.98 12.52 586 44142 954369 109590202
Pleural fibrosis 43.34 12.52 25 44703 4283 110540288
Wound 42.22 12.52 21 44707 234416 110310155
Blood immunoglobulin M increased 42.12 12.52 18 44710 1619 110542952
Rheumatic disorder 41.99 12.52 23 44705 3568 110541003
Intentional overdose 41.97 12.52 3 44725 132498 110412073
Neutropenia 41.91 12.52 54 44674 374566 110170005
Rheumatoid factor positive 41.64 12.52 3 44725 131637 110412934
Activated partial thromboplastin time prolonged 39.51 12.52 47 44681 22321 110522250
Depressed mood 38.99 12.52 80 44648 60729 110483842
Headache 38.84 12.52 535 44193 881842 109662729
Cataract operation 38.56 12.52 26 44702 5857 110538714
Injury 38.29 12.52 12 44716 177253 110367318
Abdominal pain 38.13 12.52 345 44383 512644 110031927
Anti-cyclic citrullinated peptide antibody positive 38.11 12.52 13 44715 181971 110362600
Bacteroides infection 37.78 12.52 20 44708 2899 110541672
Pericarditis 37.44 12.52 21 44707 219093 110325478
Eye disorder 37.32 12.52 52 44676 28854 110515717
Interstitial lung disease 36.94 12.52 6 44722 139328 110405243
Blood immunoglobulin A decreased 36.65 12.52 18 44710 2230 110542341
Coordination abnormal 36.55 12.52 48 44680 25180 110519391
Confusional state 36.51 12.52 85 44643 468595 110075976
Multiple allergies 36.42 12.52 34 44694 12229 110532342
Cardiac arrest 36.38 12.52 17 44711 196736 110347835
Spinal disorder 35.76 12.52 33 44695 11695 110532876
Frequent bowel movements 34.61 12.52 84 44644 71306 110473265
Aortic stenosis 34.60 12.52 34 44694 13025 110531546
End stage renal disease 34.48 12.52 43 44685 21430 110523141
Vitamin B12 deficiency 34.03 12.52 30 44698 10025 110534546
Overdose 33.77 12.52 27 44701 233767 110310804
Product dose omission issue 33.55 12.52 234 44494 321548 110223023
Haematochezia 32.69 12.52 112 44616 115412 110429159
Insomnia 32.34 12.52 253 44475 360337 110184234
Colitis ulcerative 32.27 12.52 86 44642 77277 110467294
Helicobacter infection 31.69 12.52 17 44711 181860 110362711
Dyspepsia 31.68 12.52 157 44571 190808 110353763
Throat irritation 31.48 12.52 68 44660 53484 110491087
Deafness neurosensory 31.16 12.52 28 44700 9591 110534980
Liver injury 31.05 12.52 11 44717 150402 110394169
Diarrhoea 31.05 12.52 639 44089 1138866 109405705
Chronic obstructive pulmonary disease 31.03 12.52 106 44622 109052 110435519
Hepatic enzyme abnormal 30.80 12.52 28 44700 9735 110534836
Gout 30.74 12.52 54 44674 36512 110508059
Thrombocytopenia 30.74 12.52 59 44669 348826 110195745
Epigastric discomfort 30.71 12.52 27 44701 8988 110535583
Blood immunoglobulin G increased 30.28 12.52 19 44709 3789 110540782
Blood pressure systolic decreased 30.17 12.52 32 44696 13409 110531162
Exposure during pregnancy 30.14 12.52 15 44713 167409 110377162
Lip dry 29.69 12.52 3 44725 100080 110444491
Pancytopenia 29.29 12.52 25 44703 209588 110334983
Abdominal pain upper 29.16 12.52 241 44487 348870 110195701
Balance disorder 28.71 12.52 108 44620 116452 110428119
Dermatitis atopic 28.67 12.52 43 44685 25498 110519073
Blood cholesterol increased 28.61 12.52 149 44579 184636 110359935
Cardio-respiratory arrest 28.54 12.52 6 44722 115830 110428741
Glycosylated haemoglobin increased 28.29 12.52 41 44687 23578 110520993
Cardiac failure 27.94 12.52 21 44707 187605 110356966
Bradycardia 27.89 12.52 14 44714 155503 110389068
Epilepsy 27.28 12.52 4 44724 100205 110444366
Metabolic acidosis 27.11 12.52 4 44724 99740 110444831
Body height decreased 27.06 12.52 27 44701 10536 110534035
Sinusitis 27.05 12.52 209 44519 296479 110248092
Monocyte count increased 26.96 12.52 30 44698 13263 110531308
Rubber sensitivity 26.94 12.52 15 44713 2403 110542168
Bone cyst 26.22 12.52 17 44711 3586 110540985
Facet joint syndrome 26.05 12.52 4 44724 96824 110447747
Neuropathy peripheral 26.00 12.52 142 44586 179135 110365436
Cholecystitis acute 25.98 12.52 32 44696 15750 110528821
Fatigue 25.98 12.52 659 44069 1215299 109329272
Pneumonia aspiration 25.88 12.52 82 44646 81151 110463420
Osteopenia 25.80 12.52 38 44690 22171 110522400
Septic shock 25.63 12.52 16 44712 157512 110387059
Multiple organ dysfunction syndrome 25.35 12.52 125 44603 151585 110392986
Cataract 25.11 12.52 80 44648 79405 110465166
Osteosclerosis 25.02 12.52 18 44710 4497 110540074
Aspartate aminotransferase abnormal 24.97 12.52 16 44712 3309 110541262
Vitamin D deficiency 24.89 12.52 34 44694 18518 110526053
Folliculitis 24.66 12.52 19 44709 167634 110376937
White blood cells urine positive 24.57 12.52 22 44706 7502 110537069
Bronchitis 24.56 12.52 127 44601 156905 110387666
Suicide attempt 24.18 12.52 6 44722 103388 110441183
Blood calcium increased 24.11 12.52 33 44695 18007 110526564
Hyperlipidaemia 23.97 12.52 48 44680 35800 110508771
Troponin increased 23.79 12.52 43 44685 29723 110514848
Gastrooesophageal reflux disease 23.76 12.52 139 44589 179837 110364734
Cyst 23.30 12.52 31 44697 16465 110528106
Malignant neoplasm progression 22.98 12.52 22 44706 174545 110370026
Blood alkaline phosphatase increased 22.96 12.52 72 44656 70863 110473708
Blood glucose decreased 22.81 12.52 42 44686 29446 110515125
Alanine aminotransferase increased 22.39 12.52 139 44589 183634 110360937
Colitis 22.12 12.52 91 44637 102232 110442339
Carbuncle 21.71 12.52 11 44717 1456 110543115
Night sweats 21.40 12.52 109 44619 133874 110410697
Medication error 21.25 12.52 8 44720 105358 110439213
Drug reaction with eosinophilia and systemic symptoms 20.75 12.52 4 44724 82091 110462480
Red blood cell count decreased 20.50 12.52 66 44662 65857 110478714
Nasal congestion 20.14 12.52 86 44642 98196 110446375
Herpes zoster 20.07 12.52 92 44636 108287 110436284
Intentional product use issue 20.06 12.52 44 44684 247862 110296709
Bursitis 20.05 12.52 14 44714 129904 110414667
Mucosal inflammation 19.89 12.52 7 44721 96134 110448437
Fibromyalgia 19.76 12.52 24 44704 170885 110373686
Total lung capacity decreased 19.75 12.52 19 44709 7095 110537476
Breast cancer stage III 19.69 12.52 4 44724 79113 110465458
Hypokalaemia 19.67 12.52 27 44701 182421 110362150
Multiple fractures 19.56 12.52 21 44707 8919 110535652
Cataract nuclear 19.24 12.52 10 44718 1396 110543175
Discomfort 19.17 12.52 36 44692 214671 110329900
Hepatic encephalopathy 19.09 12.52 38 44690 28218 110516353
Angioedema 19.01 12.52 8 44720 98492 110446079
Delirium 18.99 12.52 16 44712 135009 110409562
Therapeutic product effect incomplete 18.94 12.52 155 44573 223650 110320921
Intentional product misuse 18.42 12.52 104 44624 132800 110411771
Pulmonary function test decreased 18.27 12.52 20 44708 8680 110535891
Sleep disorder 18.13 12.52 140 44588 198504 110346067
Blood pressure increased 17.76 12.52 171 44557 258202 110286369
Tachycardia 17.71 12.52 41 44687 226604 110317967
Adrenal insufficiency 17.55 12.52 47 44681 42343 110502228
Dry skin 17.48 12.52 88 44640 107565 110437006
Deformity 17.37 12.52 21 44707 10139 110534432
Synovitis 17.34 12.52 55 44673 274037 110270534
Rhabdomyolysis 17.26 12.52 14 44714 120387 110424184
Lactic acidosis 17.18 12.52 8 44720 92803 110451768
Leukopenia 17.09 12.52 21 44707 148770 110395801
Diverticulitis 17.02 12.52 54 44674 53468 110491103
Hyponatraemia 16.96 12.52 148 44580 217505 110327066
White blood cell count decreased 16.86 12.52 154 44574 229236 110315335
Wound infection 16.83 12.52 9 44719 96456 110448115
Respiratory failure 16.79 12.52 39 44689 215293 110329278
Obesity 16.47 12.52 13 44715 113338 110431233
Delusional disorder, persecutory type 16.41 12.52 7 44721 627 110543944
Therapy non-responder 16.24 12.52 24 44704 157283 110387288
Depressed level of consciousness 16.16 12.52 13 44715 112265 110432306
Monoclonal immunoglobulin present 16.11 12.52 11 44717 2529 110542042
Rectal haemorrhage 16.10 12.52 93 44635 119740 110424831
Hepatic function abnormal 16.07 12.52 8 44720 89287 110455284
Melaena 16.06 12.52 4 44724 68753 110475818
Muscle injury 16.04 12.52 20 44708 140787 110403784
Congenital hiatus hernia 16.03 12.52 16 44712 6243 110538328
Peripheral venous disease 15.96 12.52 7 44721 84110 110460461
Colitis microscopic 15.68 12.52 23 44705 13371 110531200
Urticaria 15.48 12.52 197 44531 318660 110225911
Bronchopulmonary aspergillosis allergic 15.37 12.52 18 44710 8408 110536163
Flatulence 15.13 12.52 51 44677 52098 110492473
Fractional exhaled nitric oxide increased 15.05 12.52 7 44721 769 110543802
Aspartate aminotransferase increased 14.75 12.52 113 44615 159823 110384748
Lower limb fracture 14.73 12.52 6 44722 75342 110469229
Serotonin syndrome 14.70 12.52 3 44725 59150 110485421
Pain in extremity 14.47 12.52 277 44451 486841 110057730
Respiratory arrest 14.40 12.52 3 44725 58296 110486275
Rhonchi 14.34 12.52 13 44715 4505 110540066
Product administered at inappropriate site 14.21 12.52 14 44714 5379 110539192
Blood creatine phosphokinase increased 14.00 12.52 6 44722 73071 110471500
Hypotension 13.92 12.52 140 44588 523709 110020862
Cognitive disorder 13.83 12.52 71 44657 87440 110457131
Overweight 13.82 12.52 15 44713 6449 110538122
Skin reaction 13.77 12.52 28 44700 21116 110523455
Arthralgia 13.61 12.52 412 44316 779220 109765351
Skin irritation 13.59 12.52 24 44704 16295 110528276
Treatment failure 13.42 12.52 62 44666 277172 110267399
Asthenia 13.37 12.52 369 44359 688630 109855941
Pulmonary fibrosis 13.26 12.52 13 44715 102029 110442542
Grip strength decreased 13.24 12.52 8 44720 80166 110464405
C-reactive protein abnormal 13.18 12.52 20 44708 129675 110414896
Pancreatitis acute 13.15 12.52 4 44724 60270 110484301
Miosis 13.02 12.52 28 44700 21955 110522616
Wheezing 13.00 12.52 56 44672 255174 110289397
Agitation 12.93 12.52 16 44712 113035 110431536
Blister 12.78 12.52 48 44680 227328 110317243
Hypothalamo-pituitary disorder 12.77 12.52 10 44718 2836 110541735
Drug eruption 12.77 12.52 3 44725 53656 110490915
Shock 12.75 12.52 3 44725 53585 110490986
Irritable bowel syndrome 12.59 12.52 30 44698 164185 110380386

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A11HA08 ALIMENTARY TRACT AND METABOLISM
VITAMINS
OTHER PLAIN VITAMIN PREPARATIONS
Other plain vitamin preparations
CHEBI has role CHEBI:76924 plant metabolite
CHEBI has role CHEBI:77962 food antioxidant
MeSH PA D000975 Antioxidants
MeSH PA D014815 Vitamins
MeSH PA D018977 Micronutrients
MeSH PA D020011 Protective Agents
CHEBI has role CHEBI:38068 antimalarial

Related Drugs by ATC class:

A11HA Other plain vitamin preparations 10 drugs
biotincalcium pantothenatedexpanthenolinositolnicotinamidepantethinepyridoxal phosphatepyridoxineriboflavinVitamin E

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Obstruction of bile duct indication 30144000
Vitamin E deficiency indication 54137008




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.06 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Alpha-tocopherol transfer protein Transporter Kd 5.62 CHEMBL
Glutathione S-transferase P Enzyme IC50 6.30 CHEMBL

External reference:

IDSource
N0000011305 NUI
4017771 VANDF
CHEBI:753119 CHEBI
VIV PDB_CHEM_ID
CHEMBL2108106 ChEMBL_ID
D06174 KEGG_DRUG
CHEMBL3989727 ChEMBL_ID
CHEMBL47 ChEMBL_ID
C014225 MESH_SUPPLEMENTAL_RECORD_UI
10191-41-0 SECONDARY_CAS_RN
DB11635 DRUGBANK_ID
DB00163 DRUGBANK_ID
159151 RXNORM
11960 MMSL
40928 MMSL
001020 NDDF
009945 NDDF
116776001 SNOMEDCT_US
16132211000001106 SNOMEDCT_US
259666007 SNOMEDCT_US
768524003 SNOMEDCT_US
812121000168101 SNOMEDCT_US
C0606070 UMLSCUI
D024502 MESH_DESCRIPTOR_UI
14985 PUBCHEM_CID
N9PR3490H9 UNII

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
CitraNatal Harmony HUMAN PRESCRIPTION DRUG LABEL 8 0178-0798 CAPSULE, GELATIN COATED 30 [iU] ORAL UNAPPROVED DRUG OTHER 11 sections
CitraNatal Harmony HUMAN PRESCRIPTION DRUG LABEL 8 0178-0799 CAPSULE, GELATIN COATED 30 [iU] ORAL Unapproved drug other 11 sections
CitraNatal Harmony HUMAN PRESCRIPTION DRUG LABEL 8 0178-0812 CAPSULE, GELATIN COATED 30 [iU] ORAL Unapproved drug other 11 sections
VitafolOne HUMAN PRESCRIPTION DRUG LABEL 16 0642-0070 CAPSULE, GELATIN COATED 9 mg ORAL unapproved drug other 14 sections
Vitafol OBCaplet HUMAN PRESCRIPTION DRUG LABEL 15 0642-0079 TABLET 30 [iU] ORAL unapproved drug other 14 sections
Vitafol Plus HUMAN PRESCRIPTION DRUG LABEL 17 0642-0092 CAPSULE, LIQUID FILLED 10 [iU] ORAL UNAPPROVED DRUG OTHER 13 sections
Reaphirm Plant Source DHA HUMAN PRESCRIPTION DRUG LABEL 16 0642-3010 CAPSULE, GELATIN COATED 20 [iU] ORAL unapproved drug other 7 sections
St. Paul Brands Verestor HUMAN OTC DRUG LABEL 7 13411-861 CAPSULE 9 mg ORAL unapproved drug other 8 sections
JBA Verestor Mega Fiber Powder HUMAN OTC DRUG LABEL 8 13411-862 POWDER 8 mg ORAL unapproved drug other 6 sections
Quflora Pediatric HUMAN PRESCRIPTION DRUG LABEL 14 15370-103 TABLET, CHEWABLE 15 [iU] ORAL UNAPPROVED DRUG OTHER 12 sections
Quflora Pediatric HUMAN PRESCRIPTION DRUG LABEL 14 15370-104 TABLET, CHEWABLE 15 [iU] ORAL UNAPPROVED DRUG OTHER 12 sections
Quflora Pediatric HUMAN PRESCRIPTION DRUG LABEL 14 15370-105 TABLET, CHEWABLE 15 [iU] ORAL UNAPPROVED DRUG OTHER 12 sections
C-Nate DHA HUMAN PRESCRIPTION DRUG LABEL 13 23359-105 CAPSULE, GELATIN COATED 30 [iU] ORAL unapproved drug other 15 sections
PNV-Omega HUMAN PRESCRIPTION DRUG LABEL 13 42192-332 CAPSULE, GELATIN COATED 10 [iU] ORAL unapproved drug other 12 sections
Kimchi Vitaminchewable multivitamin HUMAN OTC DRUG LABEL 11 52102-1001 TABLET, CHEWABLE 1.88 mg ORAL unapproved drug other 2 sections
Floriva HUMAN PRESCRIPTION DRUG LABEL 16 52796-173 TABLET, CHEWABLE 20 [iU] ORAL UNAPPROVED DRUG OTHER 6 sections
Floriva HUMAN PRESCRIPTION DRUG LABEL 16 52796-174 TABLET, CHEWABLE 20 [iU] ORAL UNAPPROVED DRUG OTHER 6 sections
Floriva HUMAN PRESCRIPTION DRUG LABEL 16 52796-177 TABLET, CHEWABLE 20 [iU] ORAL UNAPPROVED DRUG OTHER 7 sections
Vitalipid N HUMAN PRESCRIPTION DRUG LABEL 4 65219-335 EMULSION 1 [iU] INTRAVENOUS Unapproved drug for use in drug shortage 2 sections
Vitalipid N HUMAN PRESCRIPTION DRUG LABEL 4 65219-337 EMULSION 0.70 [iU] INTRAVENOUS Unapproved drug for use in drug shortage 2 sections
Vitalipid N HUMAN PRESCRIPTION DRUG LABEL 4 65219-339 EMULSION 0.70 [iU] INTRAVENOUS Unapproved drug for use in drug shortage 2 sections
AntiphlamineCoin Plaster HUMAN OTC DRUG LABEL 7 69642-1600 PATCH 0.31 mg TOPICAL unapproved drug other 9 sections
Acne C-Patch HUMAN OTC DRUG LABEL 1 70236-103 PATCH 0.06 g TOPICAL unapproved drug other 8 sections
PRENATE DHA HUMAN PRESCRIPTION DRUG LABEL 11 75854-312 CAPSULE, GELATIN COATED 18 mg ORAL unapproved drug other 12 sections
Dechangling HUMAN OTC DRUG LABEL 12 82570-009 POWDER 2 g TOPICAL unapproved drug other 8 sections
De Haomian HUMAN OTC DRUG LABEL 5 82570-014 POWDER 7 g TOPICAL unapproved drug other 8 sections
Debaochun HUMAN OTC DRUG LABEL 7 82570-016 POWDER 2 dL TOPICAL unapproved drug other 8 sections
Deqingling HUMAN OTC DRUG LABEL 8 82570-017 POWDER 2 g TOPICAL unapproved drug other 8 sections
AnubisMed HUMAN OTC DRUG LABEL 28 83021-551 CREAM 0.01 g TOPICAL OTC monograph final 7 sections
Keylosa HUMAN PRESCRIPTION DRUG LABEL 18 83146-003 CAPSULE, COATED 30 mg ORAL unapproved drug other 3 sections