citicoline Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
664 987-78-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • citicoline
  • cytidine choline diphosphate
  • cytidine diphosphate choline
  • cytidine diphosphocholine
  • cytidine diphosphorylcholine
  • cytidoline
  • difosfocin
  • emicholine
  • choline cytidine diphosphate
  • citicholine
  • citidoline
  • corenalin
  • cyscholin
  • citicoline sodium
Donor of choline in biosynthesis of choline-containing phosphoglycerides.
  • Molecular weight: 488.33
  • Formula: C14H26N4O11P2
  • CLOGP: -6.40
  • LIPINSKI: 1
  • HAC: 15
  • HDO: 4
  • TPSA: 213.50
  • ALOGS: -1.83
  • ROTB: 10

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
ATC N06BX06 NERVOUS SYSTEM
PSYCHOANALEPTICS
PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
Other psychostimulants and nootropics
MeSH PA D002491 Central Nervous System Agents
MeSH PA D018697 Nootropic Agents
CHEBI has role CHEBI:35471 psychopharmaceuticals
CHEBI has role CHEBI:63726 neuroprotective agents
CHEBI has role CHEBI:75771 Mus musculus metabolite
CHEBI has role CHEBI:75772 bakers yeast metabolite
CHEBI has role CHEBI:77746 H. sapiens metabolites

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.08 acidic
pKa2 11.57 acidic
pKa3 13.08 acidic
pKa4 4.04 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4029346 VUID
N0000180302 NUI
D00057 KEGG_DRUG
33818-15-4 SECONDARY_CAS_RN
C0010725 UMLSCUI
CHEBI:16436 CHEBI
CDC PDB_CHEM_ID
CHEMBL1618340 ChEMBL_ID
CHEMBL1256994 ChEMBL_ID
CHEMBL1231700 ChEMBL_ID
DB12153 DRUGBANK_ID
2290 INN_ID
536BQ2JVC7 UNII
13804 PUBCHEM_CID
1099914 RXNORM
22451 MMSL
d05961 MMSL
004171 NDDF
009636 NDDF
698027009 SNOMEDCT_US
D003566 MESH_DESCRIPTOR_UI
4029346 VANDF

Pharmaceutical products:

None