phenibut 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4863 1078-21-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • phenibut hydrochloride
  • phenigamma
  • phenibut
  • fenibut
  • bifren
  • phenibut HCl
  • fenibut citrate
  • phenibut citrate
  • phenyl-GABA
phenyl deriv of GABA; RN given refers to cpd without isomeric designation; structure
  • Molecular weight: 179.22
  • Formula: C10H13NO2
  • CLOGP: -1.33
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 2
  • TPSA: 63.32
  • ALOGS: -2.06
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC N06BX22 NERVOUS SYSTEM
PSYCHOANALEPTICS
PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
Other psychostimulants and nootropics
MeSH PA D000927 Anticonvulsants
MeSH PA D002491 Central Nervous System Agents
MeSH PA D002492 Central Nervous System Depressants
MeSH PA D000697 Central Nervous System Stimulants
MeSH PA D003292 Convulsants
MeSH PA D018682 GABA Agents
MeSH PA D018755 GABA Agonists
MeSH PA D006993 Hypnotics and Sedatives
MeSH PA D018377 Neurotransmitter Agents
MeSH PA D011619 Psychotropic Drugs
MeSH PA D014149 Tranquilizing Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.95 acidic
pKa2 9.54 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
GABA-B receptor GPCR AGONIST SCIENTIFIC LITERATURE SCIENTIFIC LITERATURE

External reference:

IDSource
D10509 KEGG_DRUG
CHEBI:136039 CHEBI
CHEMBL315818 ChEMBL_ID
C008842 MESH_SUPPLEMENTAL_RECORD_UI
DB13455 DRUGBANK_ID
14113 PUBCHEM_CID
C0048007 UMLSCUI
625240H2LN UNII
I3L301AL5A UNII
T2M58D6LA8 UNII
11885 INN_ID

Pharmaceutical products:

None