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deanol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 787 | 108-01-0 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
An antidepressive agent that has also been used in the treatment of movement disorders. The mechanism of action is not well understood.
|
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,ALK,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,CHEK1,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,IRAK1,ITK,JAK1,JAK2,MAP2K6,MAP3K21,MAP3K7,MAPK7,MAPKAPK2,MET,MTOR,NTRK2,PDK2,PDK4,PIK3CD,PIM2,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ULK1 | 47 | |||
| kinase-selectivity-class | ABL2,ALK,BLK,BRAF,CAMK2D,CDK4,CSF1R,DDR1,EGFR,EIF2AK3,EPHA2,EPHB4,ERBB2,FLT3,GAK,INSR,IRAK1,IRAK3,LCK,LRRK2,LYN,MAP3K7,MAP3K9,MAP4K1,MAP4K3,MAP4K5,MAPK11,MAPK7,MET,PRKCD,PTK2,SIK2,SIK3,SRC,STK33,TEK,TTK | 37 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | N06BX04 | NERVOUS SYSTEM PSYCHOANALEPTICS PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS Other psychostimulants and nootropics |
| MeSH PA | D000928 | Antidepressive Agents |
| MeSH PA | D011619 | Psychotropic Drugs |
| MeSH PA | D018726 | Anti-Dyskinesia Agents |
| CHEBI has role | CHEBI:48578 | free radical scavengers |
| CHEBI has role | CHEBI:75358 | curing agents |
Related Drugs by ATC class:
N06BX Other psychostimulants and nootropics 19 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 9.18 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| High affinity choline transporter 1 | Transporter | Ki | 4.25 | CHEMBL | |||||
| Creatine transporter | Transporter | Ki | 4.68 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| 2N6K9DRA24 | UNII |
| N0000166807 | NUI |
| D07777 | KEGG_DRUG |
| 3116 | RXNORM |
| C0011064 | UMLSCUI |
| CHEBI:271436 | CHEBI |
| CHEMBL3833347 | ChEMBL_ID |
| CHEMBL122588 | ChEMBL_ID |
| 7902 | PUBCHEM_CID |
| DB13352 | DRUGBANK_ID |
| CHEMBL1135 | ChEMBL_ID |
| D003642 | MESH_DESCRIPTOR_UI |
| 001541 | NDDF |
| 7904003 | SNOMEDCT_US |
| 4036720 | VANDF |
Pharmaceutical products:
None