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hydrochloric acid 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4568 | 7647-01-0 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
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A strong corrosive acid that is commonly used as a laboratory reagent. It is formed by dissolving hydrogen chloride in water. GASTRIC ACID is the hydrochloric acid component of GASTRIC JUICE.
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Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Completed suicide | 64.98 | 42.77 | 20 | 118 | 96445 | 42524752 |
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Completed suicide | 61.54 | 33.01 | 24 | 307 | 242357 | 110346611 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | A09AB03 | ALIMENTARY TRACT AND METABOLISM DIGESTIVES, INCL. ENZYMES DIGESTIVES, INCL. ENZYMES Acid preparations |
| ATC | B05XA13 | BLOOD AND BLOOD FORMING ORGANS BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS I.V. SOLUTION ADDITIVES Electrolyte solutions |
| CHEBI has role | CHEBI:75771 | Mus musculus metabolites |
Related Drugs by ATC class:
A09AB Acid preparations 3 drugs
B05XA Electrolyte solutions 18 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Carbonic anhydrase 4 | Enzyme | Ki | 4.05 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| D02057 | KEGG_DRUG |
| 4018214 | VUID |
| N0000146547 | NUI |
| 4018214 | VANDF |
| CHEBI:17883 | CHEBI |
| CHEMBL1231821 | ChEMBL_ID |
| DB13366 | DRUGBANK_ID |
| QTT17582CB | UNII |
| 5486 | RXNORM |
| NOCODE | MMSL |
| 001112 | NDDF |
| 27763000 | SNOMEDCT_US |
| 420502008 | SNOMEDCT_US |
| C0020259 | UMLSCUI |
| D006851 | MESH_DESCRIPTOR_UI |
| CL | PDB_CHEM_ID |
| CLO | PDB_CHEM_ID |
| 313 | PUBCHEM_CID |
Pharmaceutical products:
None