potassium chloride 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
4199 7447-40-7

Description:

MoleculeDescription

Synonyms:

  • potassium chloride
A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.
  • Molecular weight: 74.55
  • Formula: ClK
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
3 g O

ADMET properties:

PropertyValueReference
BDDCS (Biopharmaceutical Drug Disposition Classification System) 3 Benet LZ, Broccatelli F, Oprea TI
S (Water solubility) 333.30 mg/mL Benet LZ, Broccatelli F, Oprea TI
EoM (Fraction excreted unchanged in urine) 85 % Benet LZ, Broccatelli F, Oprea TI

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

DateAgencyCompanyOrphan
Dec. 16, 1965 FDA HOSPIRA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Pemphigus 750.35 9.66 3 213106 326861 90088477
Hand deformity 658.80 9.66 7 213102 296355 90118983
Systemic lupus erythematosus 605.07 9.66 71 213038 361825 90053513
Glossodynia 597.33 9.66 41 213068 321738 90093600
Hyperkalaemia 566.96 9.66 731 212378 64233 90351105
Hypokalaemia 563.61 9.66 1064 212045 130052 90285286
Anti-cyclic citrullinated peptide antibody positive 538.02 9.66 3 213106 236430 90178908
Drug ineffective 533.93 9.66 1588 211521 1382710 89032628
Cardiac failure congestive 499.49 9.66 860 212249 97834 90317504
Duodenal ulcer perforation 483.81 9.66 7 213102 221281 90194057
Helicobacter infection 476.53 9.66 12 213097 226838 90188500
Acute kidney injury 473.87 9.66 1742 211367 318645 90096693
Anaemia 473.85 9.66 1860 211249 350942 90064396
Pericarditis 464.08 9.66 48 213061 270103 90145235
Wound 449.79 9.66 84 213025 302896 90112442
Contraindicated product administered 428.37 9.66 112 212997 320027 90095311
Joint swelling 422.34 9.66 339 212770 502961 89912377
Folliculitis 397.44 9.66 20 213089 204333 90211005
Arthropathy 392.75 9.66 185 212924 366057 90049281
Alopecia 372.67 9.66 369 212740 494702 89920636
Muscle injury 368.51 9.66 10 213099 176644 90238694
Synovitis 351.33 9.66 168 212941 329584 90085754
Dehydration 349.79 9.66 1129 211980 193318 90222020
Atrial fibrillation 340.26 9.66 879 212230 132732 90282606
Therapeutic product effect decreased 333.54 9.66 118 212991 277453 90137885
Irritable bowel syndrome 328.96 9.66 48 213061 207400 90207938
Lower respiratory tract infection 327.12 9.66 92 213017 250567 90164771
Drug intolerance 320.52 9.66 348 212761 447243 89968095
Hepatic enzyme increased 320.29 9.66 229 212880 360507 90054831
Rheumatoid arthritis 311.85 9.66 238 212871 362376 90052962
Maternal exposure during pregnancy 307.51 9.66 238 212871 359825 90055513
Discomfort 307.47 9.66 130 212979 274205 90141133
Hypervolaemia 292.61 9.66 373 212736 32384 90382954
Psoriatic arthropathy 288.44 9.66 89 213020 228246 90187092
Impaired healing 287.50 9.66 96 213013 234103 90181235
Sleep disorder due to general medical condition, insomnia type 281.52 9.66 4 213105 128690 90286648
Abdominal discomfort 274.30 9.66 437 212672 476891 89938447
Musculoskeletal stiffness 274.15 9.66 180 212929 296352 90118986
Blood potassium decreased 270.90 9.66 438 212671 47289 90368049
Treatment failure 267.04 9.66 195 212914 303733 90111605
Infusion related reaction 255.42 9.66 365 212744 416415 89998923
Liver injury 253.61 9.66 47 213062 170520 90244818
Diarrhoea 253.59 9.66 3341 209768 935849 89479489
Pulmonary hypertension 250.60 9.66 397 212712 42126 90373212
Swelling 249.95 9.66 374 212735 418684 89996654
Pneumonia 245.57 9.66 2433 210676 635626 89779712
Sepsis 243.32 9.66 951 212158 178863 90236475
Death 240.60 9.66 1866 211243 454685 89960653
Hypotension 240.59 9.66 1446 211663 323951 90091387
Ill-defined disorder 237.24 9.66 70 213039 184821 90230517
Type 2 diabetes mellitus 223.40 9.66 99 213010 203145 90212193
Hypersensitivity 222.91 9.66 459 212650 454218 89961120
Blood cholesterol increased 221.38 9.66 106 213003 207906 90207432
Joint range of motion decreased 218.24 9.66 30 213079 135613 90279725
Plasma cell myeloma 213.31 9.66 361 212748 40467 90374871
Gastrointestinal haemorrhage 211.67 9.66 576 212533 89672 90325666
Drug hypersensitivity 211.58 9.66 487 212622 463122 89952216
Fibromyalgia 207.74 9.66 113 212996 206156 90209182
Blister 202.23 9.66 181 212928 254817 90160521
Facet joint syndrome 199.99 9.66 7 213102 98382 90316956
Pulmonary arterial hypertension 198.21 9.66 275 212834 25912 90389426
Acute respiratory failure 197.65 9.66 359 212750 42559 90372779
Fall 197.29 9.66 1862 211247 479948 89935390
Oedema peripheral 193.00 9.66 1150 211959 256765 90158573
Dyspnoea 190.59 9.66 3016 210093 877939 89537399
Exposure during pregnancy 190.52 9.66 168 212941 238242 90177096
Respiratory failure 188.37 9.66 660 212449 117758 90297580
Renal failure 187.94 9.66 706 212403 130301 90285037
Cardiac failure 184.40 9.66 622 212487 108874 90306464
C-reactive protein abnormal 179.25 9.66 40 213069 127389 90287949
Lip dry 178.35 9.66 16 213093 100939 90314399
Product use issue 176.48 9.66 316 212793 329603 90085735
Grip strength decreased 173.95 9.66 11 213098 92565 90322773
Bursitis 170.41 9.66 49 213060 131605 90283733
Hyponatraemia 169.93 9.66 693 212416 132845 90282493
Right ventricular failure 168.85 9.66 217 212892 18988 90396350
Injury 165.11 9.66 133 212976 197216 90218122
Pleural effusion 161.01 9.66 604 212505 111387 90303951
Sleep disorder 154.08 9.66 143 212966 197887 90217451
Colitis microscopic 151.94 9.66 158 212951 11001 90404337
Hypoxia 148.22 9.66 440 212669 71959 90343379
Stomatitis 146.07 9.66 264 212845 274434 90140904
Mobility decreased 145.28 9.66 228 212881 250506 90164832
Arthralgia 143.39 9.66 1158 211951 777364 89637974
Constipation 142.44 9.66 1137 211972 279258 90136080
Intentional product use issue 140.73 9.66 182 212927 216710 90198628
International normalised ratio increased 139.07 9.66 329 212780 46987 90368351
Chronic obstructive pulmonary disease 138.34 9.66 435 212674 73394 90341944
Colitis 136.52 9.66 418 212691 69524 90345814
Urinary tract infection 136.48 9.66 1204 211905 304428 90110910
Off label use 136.00 9.66 1803 211306 1100449 89314889
Rash 135.89 9.66 1208 211901 794892 89620446
Hypercholesterolaemia 135.36 9.66 35 213074 100857 90314481
Inflammation 131.94 9.66 135 212974 178457 90236881
Urticaria 128.87 9.66 346 212763 312388 90102950
Deep vein thrombosis 124.17 9.66 485 212624 91135 90324203
Macular degeneration 123.72 9.66 275 212834 37695 90377643
Nasopharyngitis 122.24 9.66 517 212592 406587 90008751
Night sweats 120.48 9.66 77 213032 128689 90286649
Pneumonia aspiration 119.59 9.66 284 212825 40656 90374682
Gastrointestinal disorder 118.26 9.66 268 212841 256419 90158919
Wheezing 116.80 9.66 240 212869 237840 90177498
Prescribed overdose 114.62 9.66 43 213066 97582 90317756
Toxic anterior segment syndrome 113.50 9.66 69 213040 2181 90413157
Vaginal flatulence 112.99 9.66 144 212965 12494 90402844
Product use in unapproved indication 111.09 9.66 411 212698 335825 90079513
Autoimmune disorder 108.10 9.66 24 213085 76720 90338618
Wound infection 107.50 9.66 58 213051 106344 90308994
Febrile neutropenia 106.98 9.66 688 212421 157661 90257677
Pain 106.52 9.66 1676 211433 994665 89420673
Syncope 105.25 9.66 601 212508 132062 90283276
Live birth 105.05 9.66 28 213081 79079 90336259
Osteoarthritis 105.00 9.66 187 212922 195543 90219795
Proctitis 104.80 9.66 153 212956 15106 90400232
Fluid retention 103.32 9.66 446 212663 87645 90327693
Blepharospasm 100.08 9.66 8 213101 55437 90359901
Bronchitis 99.99 9.66 659 212450 152268 90263070
Platelet count decreased 99.95 9.66 607 212502 136362 90278976
Pulmonary fibrosis 99.59 9.66 65 213044 107438 90307900
Pancytopenia 98.82 9.66 550 212559 119713 90295625
Pulmonary embolism 98.81 9.66 585 212524 130235 90285103
Female genital tract fistula 97.33 9.66 161 212948 17707 90397631
Glaucoma 97.31 9.66 175 212934 20580 90394758
Peripheral venous disease 96.80 9.66 38 213071 83883 90331455
Radiculopathy 95.82 9.66 163 212946 18342 90396996
Hip arthroplasty 95.63 9.66 30 213079 76178 90339160
Cardiac arrest 95.11 9.66 493 212616 104442 90310896
Cytokine release syndrome 93.85 9.66 205 212904 27768 90387570
Pulmonary oedema 93.53 9.66 340 212769 61740 90353598
Asthenia 92.47 9.66 1765 211344 531986 89883352
Hypomagnesaemia 92.42 9.66 236 212873 35352 90379986
Chronic sinusitis 92.19 9.66 185 212924 23617 90391721
Diverticulitis 91.88 9.66 274 212835 44913 90370425
Coeliac disease 91.26 9.66 3 213106 44607 90370731
Haemoglobin decreased 90.66 9.66 672 212437 161284 90254054
Dyspnoea exertional 87.87 9.66 370 212739 71918 90343420
Product residue present 87.56 9.66 76 213033 4215 90411123
Dementia 87.14 9.66 181 212928 23680 90391658
Thrombocytopenia 86.34 9.66 809 212300 207916 90207422
Infection 86.11 9.66 499 212610 361595 90053743
White blood cell count decreased 83.33 9.66 675 212434 166434 90248904
Gait inability 83.06 9.66 135 212974 146321 90269017
Paraesthesia oral 81.23 9.66 209 212900 31450 90383888
Electrolyte imbalance 79.65 9.66 174 212935 23571 90391767
Oral candidiasis 76.89 9.66 220 212889 35235 90380103
Obesity 76.49 9.66 81 213028 105426 90309912
Device expulsion 76.38 9.66 5 213104 40881 90374457
Drug abuse 75.99 9.66 50 213059 82297 90333041
Sinusitis 74.69 9.66 486 212623 342602 90072736
Neuropathy peripheral 74.20 9.66 564 212545 136406 90278932
Full blood count decreased 74.13 9.66 194 212915 29495 90385843
Condition aggravated 73.90 9.66 972 212137 594573 89820765
Psoriasis 73.23 9.66 148 212961 147606 90267732
Onychomadesis 72.04 9.66 11 213098 45987 90369351
Vaginal discharge 71.49 9.66 148 212961 19316 90396022
Lupus-like syndrome 71.42 9.66 14 213095 48832 90366506
Haematoma 71.23 9.66 228 212881 38820 90376518
Joint stiffness 71.18 9.66 48 213061 77994 90337344
Nail disorder 71.05 9.66 25 213084 59042 90356296
Weight decreased 70.82 9.66 1271 211838 378639 90036699
Transfusion 70.22 9.66 138 212971 17350 90397988
Bone erosion 69.96 9.66 19 213090 53002 90362336
Toxicity to various agents 69.85 9.66 394 212715 287452 90127886
Melaena 69.80 9.66 210 212899 34587 90380751
Blood alkaline phosphatase increased 69.64 9.66 260 212849 47819 90367519
Cerebrovascular accident 67.10 9.66 509 212600 123024 90292314
Cellulitis 66.75 9.66 405 212704 90932 90324406
Rectal haemorrhage 66.36 9.66 376 212733 82368 90332970
Blood urea increased 66.23 9.66 189 212920 30224 90385114
Dry mouth 66.10 9.66 217 212892 183842 90231496
Road traffic accident 66.04 9.66 94 213015 107532 90307806
Epistaxis 65.77 9.66 383 212726 84742 90330596
Thrombosis 65.58 9.66 343 212766 72908 90342430
Lower limb fracture 65.37 9.66 62 213047 84951 90330387
Clostridium difficile colitis 65.14 9.66 173 212936 26533 90388805
Finger deformity 64.62 9.66 3 213106 32894 90382444
Epilepsy 64.33 9.66 59 213050 82147 90333191
Mental status changes 64.20 9.66 241 212868 44438 90370900
Cardiomegaly 63.84 9.66 139 212970 18786 90396552
Knee arthroplasty 63.57 9.66 61 213048 83121 90332217
Blood loss anaemia 62.97 9.66 97 213012 10043 90405295
Hypocalcaemia 62.94 9.66 231 212878 42137 90373201
Injection site reaction 62.05 9.66 75 213034 92005 90323333
Atrial flutter 61.39 9.66 99 213010 10659 90404679
Haematochezia 61.39 9.66 329 212780 70584 90344754
Brain natriuretic peptide increased 61.06 9.66 73 213036 5932 90409406
Foot deformity 61.00 9.66 32 213077 59619 90355719
Ascites 60.87 9.66 248 212861 47492 90367846
Coma 60.87 9.66 334 212775 72298 90343040
Blood creatinine increased 60.35 9.66 427 212682 100959 90314379
Red blood cell sedimentation rate increased 60.33 9.66 63 213046 82532 90332806
Septic shock 60.12 9.66 371 212738 83789 90331549
Pregnancy 59.55 9.66 36 213073 62011 90353327
Respiratory distress 59.25 9.66 214 212895 38732 90376606
Procedural pain 59.23 9.66 193 212916 33167 90382171
Hyperaldosteronism 59.14 9.66 24 213085 306 90415032
Arrhythmia 58.89 9.66 226 212883 42106 90373232
Blood bilirubin increased 57.97 9.66 229 212880 43241 90372097
Onychomycosis 56.17 9.66 10 213099 37366 90377972
Hypoaesthesia 55.96 9.66 471 212638 313739 90101599
Metabolic encephalopathy 55.79 9.66 74 213035 6678 90408660
Adverse event 55.34 9.66 121 212988 117297 90298041
Encephalopathy 55.10 9.66 236 212873 46208 90369130
Prescribed underdose 55.04 9.66 57 213052 74962 90340376
Exostosis 53.61 9.66 29 213080 53105 90362233
Sciatica 53.32 9.66 98 213011 101284 90314054
Cardiac failure acute 52.66 9.66 98 213011 11831 90403507
Therapy non-responder 52.01 9.66 157 212952 136547 90278791
Vascular device infection 51.28 9.66 97 213012 11855 90403483
Myocardial infarction 50.63 9.66 424 212685 105548 90309790
Nausea 50.06 9.66 3135 209974 1107181 89308157
Toxic epidermal necrolysis 49.71 9.66 179 212930 32349 90382989
Drug ineffective for unapproved indication 49.62 9.66 50 213059 66594 90348744
Gout 48.20 9.66 116 212993 16743 90398595
Blood glucose increased 48.14 9.66 386 212723 94860 90320478
Migraine 48.14 9.66 257 212852 190135 90225203
Hypoglycaemia 48.07 9.66 305 212804 69543 90345795
Musculoskeletal pain 47.97 9.66 223 212886 171028 90244310
Liver disorder 47.78 9.66 137 212972 121132 90294206
Cholestasis 47.42 9.66 190 212919 36109 90379229
Blood cholesterol decreased 47.28 9.66 38 213071 1893 90413445
Cor pulmonale 47.19 9.66 39 213070 2021 90413317
Bradycardia 46.94 9.66 348 212761 83499 90331839
Oxygen saturation decreased 46.12 9.66 420 212689 107063 90308275
Taste disorder 46.02 9.66 46 213063 61500 90353838
Blood magnesium decreased 45.97 9.66 109 213000 15584 90399754
Oxygen consumption increased 45.37 9.66 55 213054 4534 90410804
Lung disorder 45.11 9.66 190 212919 149693 90265645
Disability 44.49 9.66 20 213089 40725 90374613
Metabolic alkalosis 44.33 9.66 48 213061 3501 90411837
Blood potassium increased 43.30 9.66 127 212982 20622 90394716
Catheter management 43.16 9.66 44 213065 2992 90412346
General physical health deterioration 42.72 9.66 583 212526 354532 90060806
Neutropenia 42.40 9.66 754 212355 224150 90191188
Abdominal pain 42.27 9.66 1224 211885 394497 90020841
Somnolence 41.59 9.66 707 212402 208377 90206961
Asthma 41.31 9.66 367 212742 241793 90173545
Multiple allergies 40.95 9.66 102 213007 15044 90400294
Hospice care 40.70 9.66 78 213031 9626 90405712
Gastritis 40.51 9.66 200 212909 41553 90373785
Peripheral circulatory failure 40.20 9.66 32 213077 1572 90413766
Malnutrition 40.09 9.66 115 212994 18443 90396895
Left ventricular failure 40.08 9.66 63 213046 6637 90408701
Aspartate aminotransferase increased 40.06 9.66 394 212715 102543 90312795
Haemoptysis 40.05 9.66 170 212939 33150 90382188
Hypophagia 39.88 9.66 179 212930 35758 90379580
Gastric polyps 39.83 9.66 52 213057 4620 90410718
Contusion 39.73 9.66 388 212721 250828 90164510
Haematocrit decreased 39.61 9.66 199 212910 41633 90373705
Back injury 39.49 9.66 31 213078 46591 90368747
Walking aid user 39.45 9.66 17 213092 35489 90379849
Drug-induced liver injury 39.40 9.66 97 213012 90221 90325117
Hyperglycaemia 39.15 9.66 229 212880 50741 90364597
Peritonitis bacterial 38.67 9.66 54 213055 5117 90410221
Abortion spontaneous 38.62 9.66 42 213067 54014 90361324
Pericardial effusion 38.31 9.66 180 212929 36653 90378685
Subileus 38.21 9.66 45 213064 3599 90411739
Therapeutic product effect incomplete 38.04 9.66 283 212826 193613 90221725
Laryngitis 37.87 9.66 38 213071 50715 90364623
Hypoalbuminaemia 37.78 9.66 102 213007 15795 90399543
Subdural haematoma 37.77 9.66 105 213004 16540 90398798
Arteriosclerosis coronary artery 37.62 9.66 75 213034 9528 90405810
Transient ischaemic attack 37.15 9.66 200 212909 42976 90372362
Arthritis 36.88 9.66 236 212873 167079 90248259
Pseudomonal sepsis 36.86 9.66 48 213061 4254 90411084
Orthopnoea 36.44 9.66 61 213048 6774 90408564
Chronic kidney disease 36.31 9.66 222 212887 49969 90365369
Neuroglycopenia 36.27 9.66 26 213083 1089 90414249
Rheumatoid nodule 36.14 9.66 3 213106 20163 90395175
Joint dislocation 36.08 9.66 31 213078 44551 90370787
Cardiac disorder 35.29 9.66 242 212867 56630 90358708
Adverse reaction 35.01 9.66 13 213096 29699 90385639
Drug tolerance decreased 34.73 9.66 16 213093 32114 90383224
Head injury 34.35 9.66 155 212954 31033 90384305
Cardiogenic shock 34.33 9.66 131 212978 24337 90391001
Hyperkaliuria 34.22 9.66 11 213098 67 90415271
Injection site swelling 34.06 9.66 55 213054 59784 90355554
Clostridium difficile infection 34.02 9.66 172 212937 36073 90379265
Hypophosphataemia 34.00 9.66 94 213015 14760 90400578
Disease progression 33.88 9.66 537 212572 156078 90259260
Maternal exposure timing unspecified 33.82 9.66 6 213103 22477 90392861
Generalised oedema 33.62 9.66 110 212999 18943 90396395
Electrocardiogram T wave peaked 33.45 9.66 15 213094 248 90415090
Weight increased 33.23 9.66 739 212370 417188 89998150
Prothrombin time prolonged 33.22 9.66 72 213037 9700 90405638
Unevaluable event 33.21 9.66 232 212877 54616 90360722
Blood potassium abnormal 33.11 9.66 38 213071 2956 90412382
Pain in jaw 32.69 9.66 209 212900 47776 90367562
Adverse drug reaction 32.66 9.66 152 212957 116549 90298789
Product dose omission issue 32.44 9.66 907 212202 290780 90124558
Cerebral haematoma 32.39 9.66 45 213064 4244 90411094
Haemorrhage 32.30 9.66 276 212833 69093 90346245
Pseudomonal bacteraemia 32.24 9.66 31 213078 1963 90413375
Coronary artery disease 31.87 9.66 160 212949 33463 90381875
Skin reaction 31.74 9.66 106 213003 18447 90396891
Atrioventricular block first degree 31.59 9.66 65 213044 8446 90406892
Paraesthesia 31.53 9.66 407 212702 249919 90165419
Leukocytosis 31.18 9.66 150 212959 30840 90384498
Product quality issue 30.96 9.66 90 213019 79235 90336103
Emphysema 30.93 9.66 80 213029 12075 90403263
Therapeutic response decreased 30.69 9.66 108 213001 89621 90325717
Electrocardiogram abnormal 30.68 9.66 72 213037 10226 90405112
Hypernatraemia 30.59 9.66 68 213041 9319 90406019
Supraventricular tachycardia 30.35 9.66 96 213013 16240 90399098
Troponin increased 30.35 9.66 84 213025 13197 90402141
Food allergy 30.27 9.66 11 213098 25467 90389871
Hypertension 29.88 9.66 833 212276 456699 89958639
Vascular encephalopathy 29.85 9.66 20 213089 750 90414588
Failure to thrive 29.77 9.66 63 213046 8348 90406990
Atelectasis 29.70 9.66 125 212984 24284 90391054
Immune effector cell-associated neurotoxicity syndrome 28.80 9.66 50 213059 5718 90409620
Hiatus hernia 28.65 9.66 127 212982 25234 90390104
Lymphoedema 28.53 9.66 84 213025 13669 90401669
Presyncope 28.51 9.66 149 212960 31656 90383682
Hypercapnia 28.41 9.66 54 213055 6623 90408715
Acute motor-sensory axonal neuropathy 28.39 9.66 15 213094 360 90414978
Blood pressure decreased 28.33 9.66 285 212824 74610 90340728
Device related infection 28.28 9.66 128 212981 25658 90389680
Intentional self-injury 28.17 9.66 17 213092 29317 90386021
Blood albumin decreased 27.86 9.66 95 213014 16708 90398630
Electrocardiogram U wave present 27.64 9.66 10 213099 91 90415247
Cardioactive drug level increased 27.62 9.66 31 213078 2353 90412985
Urosepsis 27.62 9.66 111 212998 21121 90394217
Acute myocardial infarction 27.60 9.66 158 212951 34732 90380606
Polyuria 27.55 9.66 68 213041 9972 90405366
Chronic respiratory failure 27.34 9.66 33 213076 2708 90412630
Liver function test increased 27.14 9.66 105 213004 84750 90330588
Rash vesicular 27.06 9.66 5 213104 18192 90397146
Muscle spasticity 26.87 9.66 26 213083 35296 90380042
Endophthalmitis 26.58 9.66 43 213066 4642 90410696
Acute left ventricular failure 26.54 9.66 23 213086 1273 90414065
Loss of personal independence in daily activities 26.52 9.66 199 212910 135906 90279432
Chills 26.49 9.66 447 212662 131534 90283804
Cerebral haemorrhage 26.44 9.66 155 212954 34367 90380971
Lower gastrointestinal haemorrhage 26.30 9.66 62 213047 8830 90406508
Hypovolaemia 25.85 9.66 76 213033 12355 90402983
Activated partial thromboplastin time prolonged 25.85 9.66 57 213052 7768 90407570
Dysuria 25.85 9.66 170 212939 39231 90376107
Hyperthyroidism 25.67 9.66 98 213011 18212 90397126
Blood immunoglobulin M increased 25.40 9.66 23 213086 1349 90413989
Polyarthritis 25.32 9.66 6 213103 18344 90396994
Suicidal ideation 25.19 9.66 89 213020 73766 90341572
Coagulopathy 25.09 9.66 115 212994 23174 90392164
Oesophageal spasm 24.99 9.66 35 213074 3326 90412012
Neonatal gastrointestinal disorder 24.96 9.66 9 213100 81 90415257
Nasal mucosal disorder 24.75 9.66 26 213083 1831 90413507
Streptococcal sepsis 24.70 9.66 36 213073 3548 90411790
Cholelithiasis 24.49 9.66 209 212900 52297 90363041
Blood chloride decreased 24.33 9.66 49 213060 6270 90409068
Acute pulmonary oedema 24.32 9.66 63 213046 9517 90405821
Pneumonia staphylococcal 24.27 9.66 36 213073 3605 90411733
General symptom 24.17 9.66 3 213106 14665 90400673
Calcium deficiency 24.00 9.66 22 213087 1311 90414027
Hemianopia 24.00 9.66 27 213082 2055 90413283
Haematuria 23.69 9.66 152 212957 34785 90380553
Pulmonary arterial pressure increased 23.67 9.66 37 213072 3879 90411459
Nail bed inflammation 23.62 9.66 25 213084 1776 90413562
Micturition disorder 23.28 9.66 32 213077 2988 90412350
Lung infiltration 23.27 9.66 84 213025 15198 90400140
Fluid replacement 23.21 9.66 16 213093 629 90414709
Haemorrhoids 23.18 9.66 124 212985 26578 90388760
Hyperlipidaemia 23.11 9.66 111 212998 22805 90392533
Confusional state 22.99 9.66 712 212397 385493 90029845
Small intestinal obstruction 22.99 9.66 105 213004 21129 90394209
Upper gastrointestinal haemorrhage 22.96 9.66 111 212998 22865 90392473
Arteriovenous malformation 22.95 9.66 23 213086 1532 90413806
Occult blood positive 22.92 9.66 37 213072 3986 90411352
Body height decreased 22.92 9.66 71 213038 11878 90403460
Palpitations 22.85 9.66 450 212659 136278 90279060
Injection site pain 22.77 9.66 280 212829 173419 90241919
Haemorrhoidal haemorrhage 22.59 9.66 43 213066 5280 90410058
Back pain 22.50 9.66 936 212173 316239 90099099
Nodal arrhythmia 22.49 9.66 21 213088 1282 90414056
Bacteraemia 22.48 9.66 108 213001 22192 90393146
Blood sodium decreased 22.47 9.66 126 212983 27487 90387851
Haematemesis 22.42 9.66 146 212963 33580 90381758
Schizophrenia 22.39 9.66 4 213105 14910 90400428
Blood immunoglobulin A decreased 22.37 9.66 24 213085 1732 90413606
Scleroderma 22.28 9.66 47 213062 6214 90409124
Foetal exposure during pregnancy 22.19 9.66 42 213067 42933 90372405
Blood immunoglobulin G increased 22.17 9.66 31 213078 2941 90412397
Iron deficiency anaemia 22.00 9.66 112 212997 23550 90391788
Parkinsonism 22.00 9.66 78 213031 13987 90401351
Mitral valve incompetence 21.92 9.66 108 213001 22416 90392922
Urinary retention 21.89 9.66 158 212951 37586 90377752
Pneumothorax spontaneous 21.88 9.66 18 213091 927 90414411
Blood glucose decreased 21.86 9.66 111 212998 23318 90392020
Confusion postoperative 21.77 9.66 11 213098 240 90415098
Subcutaneous drug absorption impaired 21.77 9.66 3 213106 13542 90401796
Hepatitis 21.69 9.66 89 213020 70650 90344688
Ageusia 21.68 9.66 85 213024 15991 90399347
Ear infection 21.27 9.66 88 213021 69687 90345651
Suicide attempt 21.21 9.66 98 213011 75301 90340037
Tonsillar haemorrhage 21.20 9.66 11 213098 254 90415084
Feeling abnormal 21.17 9.66 529 212580 166706 90248632
Blood creatine increased 21.07 9.66 49 213060 6918 90408420
Paracentesis 21.07 9.66 18 213091 977 90414361
Chronic left ventricular failure 21.04 9.66 15 213094 623 90414715
Haemoglobin increased 20.88 9.66 51 213058 7430 90407908
Urine chloride decreased 20.85 9.66 8 213101 87 90415251
Red blood cell count decreased 20.84 9.66 183 212926 46168 90369170
Cough 20.81 9.66 1064 212045 367898 90047440
Thyroid disorder 20.80 9.66 90 213019 17695 90397643
Catheter site infection 20.77 9.66 43 213066 5611 90409727
Device related sepsis 20.69 9.66 39 213070 4754 90410584
Diabetes mellitus inadequate control 20.68 9.66 93 213016 18591 90396747
Oesophageal pain 20.66 9.66 37 213072 4337 90411001
Delirium 20.61 9.66 152 212957 104207 90311131
Varicose vein 20.50 9.66 50 213059 7277 90408061
Ventricular tachycardia 20.28 9.66 113 212996 24595 90390743
Toxic skin eruption 20.15 9.66 82 213027 15692 90399646
Shock haemorrhagic 20.10 9.66 69 213040 12176 90403162
Dermatitis contact 20.08 9.66 74 213035 13521 90401817
Decreased appetite 20.06 9.66 1080 212029 375460 90039878
Candida infection 20.00 9.66 143 212966 33914 90381424
Dermatitis exfoliative generalised 19.92 9.66 42 213067 5551 90409787
Wrong patient received product 19.84 9.66 32 213077 3445 90411893
Orthostatic hypotension 19.78 9.66 167 212942 41660 90373678
Accidental exposure to product 19.67 9.66 44 213065 42322 90373016
Congenital osteodystrophy 19.65 9.66 6 213103 30 90415308
Tenosynovitis 19.63 9.66 5 213104 14562 90400776
Staphylococcal infection 19.62 9.66 187 212922 48252 90367086
Acute coronary syndrome 19.59 9.66 63 213046 10750 90404588
Lactic acidosis 19.55 9.66 193 212916 50270 90365068
Hepatotoxicity 19.39 9.66 50 213059 45792 90369546
Peptic ulcer 19.37 9.66 41 213068 5434 90409904
Incorrect route of product administration 19.35 9.66 58 213051 50568 90364770
Stupor 19.33 9.66 41 213068 5441 90409897
Gastrooesophageal reflux disease 19.26 9.66 520 212589 165817 90249521
Injection site erythema 19.20 9.66 144 212965 98358 90316980
Skin candida 19.09 9.66 22 213087 1719 90413619
Sleep apnoea syndrome 19.05 9.66 134 212975 31613 90383725
Blood parathyroid hormone decreased 18.95 9.66 3 213106 12213 90403125
Pustular psoriasis 18.90 9.66 10 213099 18546 90396792
Product compounding quality issue 18.88 9.66 6 213103 35 90415303
Congestive hepatopathy 18.81 9.66 29 213080 3004 90412334
Pulse absent 18.77 9.66 43 213066 6012 90409326
Ear pain 18.71 9.66 71 213038 57631 90357707
Ischaemic stroke 18.61 9.66 102 213007 22064 90393274
Wrong strength 18.59 9.66 7 213102 72 90415266
Catheter site haemorrhage 18.58 9.66 32 213077 3636 90411702
Nail dystrophy 18.55 9.66 19 213090 1299 90414039
Initial insomnia 18.49 9.66 56 213053 9254 90406084
Erythema 18.47 9.66 686 212423 228560 90186778
Abdominal pain upper 18.43 9.66 619 212490 332055 90083283
Enterococcus test positive 18.42 9.66 19 213090 1310 90414028
Prothrombin consumption time prolonged 18.33 9.66 6 213103 39 90415299
Agranulocytosis 18.31 9.66 143 212966 34859 90380479
Cardio-respiratory arrest 18.29 9.66 228 212881 62912 90352426
Aortic valve disease 18.22 9.66 19 213090 1327 90414011
Neonatal respiratory depression 18.21 9.66 9 213100 187 90415151
Mental status changes postoperative 18.12 9.66 9 213100 189 90415149
Drug eruption 17.93 9.66 35 213074 35372 90379966
Dermatitis exfoliative 17.92 9.66 40 213069 5496 90409842
Gastroenteritis 17.91 9.66 124 212985 29105 90386233
Hydronephrosis 17.90 9.66 67 213042 12335 90403003
Cystitis 17.67 9.66 237 212872 66481 90348857
Vascular purpura 17.46 9.66 21 213088 1717 90413621
Pruritus 17.46 9.66 1069 212040 540456 89874882
Sinus node dysfunction 17.40 9.66 39 213070 5373 90409965
Personality disorder 17.30 9.66 4 213105 12440 90402898
Congestive cardiomyopathy 17.29 9.66 47 213062 7307 90408031
Foetal death 17.27 9.66 14 213095 20709 90394629
Cataract operation 17.19 9.66 42 213067 6121 90409217
Blood pressure diastolic abnormal 17.11 9.66 13 213096 19868 90395470
Spontaneous haemorrhage 17.05 9.66 14 213095 719 90414619
Alanine aminotransferase increased 17.01 9.66 381 212728 117957 90297381
Neutrophil count decreased 16.90 9.66 249 212860 71283 90344055
Purging 16.84 9.66 6 213103 52 90415286
Bezoar 16.76 9.66 26 213083 2708 90412630
Lung perforation 16.72 9.66 7 213102 97 90415241
Muscle haemorrhage 16.70 9.66 29 213080 3317 90412021
Infusion site pain 16.69 9.66 91 213018 19647 90395691
Nodule 16.67 9.66 23 213086 26663 90388675
Hernia 16.63 9.66 72 213037 14159 90401179
Altered visual depth perception 16.60 9.66 11 213098 405 90414933
Intensive care 16.59 9.66 18 213091 1316 90414022
Nasal congestion 16.54 9.66 282 212827 83132 90332206
Anterior chamber inflammation 16.50 9.66 11 213098 409 90414929
Faecaloma 16.45 9.66 58 213051 10373 90404965
Blood pressure systolic abnormal 16.43 9.66 13 213096 19465 90395873
Urine sodium decreased 16.37 9.66 8 213101 162 90415176
Alkalosis hypochloraemic 16.35 9.66 9 213100 235 90415103
Rheumatic disorder 16.31 9.66 29 213080 3379 90411959
International normalised ratio decreased 16.28 9.66 35 213074 4689 90410649
Catheterisation cardiac 16.26 9.66 36 213073 4920 90410418
Post procedural complication 16.24 9.66 88 213021 18954 90396384
Abdominal distension 16.19 9.66 412 212697 130189 90285149
Multiple organ dysfunction syndrome 16.19 9.66 238 212871 68098 90347240
Hypochloraemia 16.16 9.66 25 213084 2597 90412741
Hospitalisation 16.14 9.66 405 212704 127695 90287643
Disseminated intravascular coagulation 16.04 9.66 96 213013 21442 90393896
Sedation complication 16.02 9.66 10 213099 16934 90398404
Insomnia 15.88 9.66 632 212477 332842 90082496
Chest pain 15.87 9.66 911 212198 318734 90096604
Wrong technique in product usage process 15.74 9.66 101 213008 71470 90343868
Completed suicide 15.72 9.66 243 212866 144815 90270523
Intentional overdose 15.64 9.66 143 212966 93691 90321647
Diverticulum intestinal haemorrhagic 15.64 9.66 20 213089 1741 90413597
Organ failure 15.61 9.66 27 213082 3078 90412260
Hip fracture 15.61 9.66 132 212977 32945 90382393
Gestational diabetes 15.54 9.66 3 213106 10579 90404759
Genital erosion 15.53 9.66 11 213098 452 90414886
Diverticulum 15.50 9.66 63 213046 12050 90403288
Hypoxic-ischaemic encephalopathy 15.42 9.66 34 213075 4634 90410704
Spondylitis 15.42 9.66 7 213102 14171 90401167
Alkalosis 15.39 9.66 12 213097 572 90414766
Tracheal obstruction 15.28 9.66 7 213102 122 90415216
Complication of device insertion 15.24 9.66 3 213106 10433 90404905
Sleep disorder due to a general medical condition 15.19 9.66 54 213055 44684 90370654
Embolism 15.19 9.66 53 213056 9428 90405910
Congenital bowing of long bones 15.19 9.66 6 213103 71 90415267
Product selection error 15.17 9.66 9 213100 272 90415066
Wrong patient 15.15 9.66 14 213095 843 90414495
Pulmonary thrombosis 15.09 9.66 54 213055 9728 90405610
Adenocarcinoma 15.05 9.66 27 213082 3169 90412169
Frequent bowel movements 14.98 9.66 202 212907 56733 90358605
Localised oedema 14.98 9.66 40 213069 6154 90409184
Impaired work ability 14.96 9.66 14 213095 19312 90396026
Paralysis recurrent laryngeal nerve 14.96 9.66 6 213103 74 90415264
Myositis 14.87 9.66 21 213088 24107 90391231
Haematoma muscle 14.86 9.66 20 213089 1830 90413508
Stevens-Johnson syndrome 14.81 9.66 119 212990 29257 90386081
Hyperdynamic left ventricle 14.79 9.66 9 213100 285 90415053
Blood phosphorus decreased 14.78 9.66 35 213074 4999 90410339
Cardiac amyloidosis 14.70 9.66 15 213094 1021 90414317
Staphylococcal sepsis 14.65 9.66 52 213057 9331 90406007
Heparin-induced thrombocytopenia 14.60 9.66 36 213073 5276 90410062
Product prescribing error 14.59 9.66 121 212988 30024 90385314
Acne 14.59 9.66 28 213081 28479 90386859
Obstructive airways disorder 14.51 9.66 24 213085 25845 90389493
Essential hypertension 14.49 9.66 40 213069 6275 90409063
Osmotic demyelination syndrome 14.49 9.66 15 213094 1039 90414299
Ileus 14.47 9.66 77 213032 16469 90398869
Cardiac operation 14.47 9.66 30 213079 3919 90411419
Hepatic failure 14.46 9.66 150 212959 39578 90375760
C-reactive protein increased 14.31 9.66 321 212788 181068 90234270
Subclavian vein thrombosis 14.22 9.66 21 213088 2095 90413243
Gamma-glutamyltransferase increased 14.15 9.66 144 212965 37808 90377530
Right atrial pressure increased 14.14 9.66 7 213102 146 90415192
Injection site bruising 14.12 9.66 69 213040 52238 90363100
Catheter placement 14.09 9.66 23 213086 2501 90412837
Pulmonary congestion 14.08 9.66 86 213023 19347 90395991
Poor peripheral circulation 14.08 9.66 30 213079 3995 90411343
Metabolic acidosis 14.02 9.66 196 212913 55480 90359858
Thoracic operation 13.97 9.66 7 213102 150 90415188
Atrioventricular block 13.89 9.66 49 213060 8766 90406572
Coronary artery occlusion 13.87 9.66 48 213061 8506 90406832
Flail chest 13.85 9.66 6 213103 91 90415247
Drug tolerance 13.85 9.66 13 213096 17903 90397435
Drug resistance 13.83 9.66 32 213077 30417 90384921
Right ventricular dysfunction 13.82 9.66 22 213087 2342 90412996
Cardiorenal syndrome 13.82 9.66 15 213094 1097 90414241
Seasonal allergy 13.79 9.66 97 213012 22886 90392452
Multiple drug therapy 13.77 9.66 42 213067 6967 90408371
Endometrial disorder 13.72 9.66 13 213096 808 90414530
Thyroxine decreased 13.71 9.66 12 213097 673 90414665
Skin dystrophy 13.68 9.66 5 213104 47 90415291
Bradykinesia 13.64 9.66 41 213068 6747 90408591
Cardiovascular insufficiency 13.63 9.66 18 213091 1617 90413721
Petechiae 13.60 9.66 73 213036 15668 90399670
Ejection fraction decreased 13.59 9.66 107 213002 26146 90389192
Deficiency anaemia 13.58 9.66 5 213104 48 90415290
Nervousness 13.56 9.66 131 212978 33925 90381413
Acute myeloid leukaemia 13.51 9.66 89 213020 20551 90394787
Anticoagulation drug level above therapeutic 13.49 9.66 20 213089 2002 90413336
Skin laceration 13.42 9.66 106 213003 25929 90389409
Cataract operation complication 13.40 9.66 7 213102 164 90415174
Faeces discoloured 13.39 9.66 91 213018 21229 90394109
Neck pain 13.35 9.66 188 212921 113775 90301563
Ulcer haemorrhage 13.35 9.66 26 213083 26295 90389043
Cardiac pacemaker insertion 13.33 9.66 31 213078 4376 90410962
Dysphagia 13.28 9.66 352 212757 111926 90303412
Pneumonia klebsiella 13.26 9.66 25 213084 3047 90412291
Decubitus ulcer 13.23 9.66 59 213050 11754 90403584
Cardiac failure chronic 13.19 9.66 36 213073 5610 90409728
Chest discomfort 13.13 9.66 422 212687 137943 90277395
Atrioventricular block second degree 13.12 9.66 31 213078 4421 90410917
Oxygen therapy 13.09 9.66 25 213084 3077 90412261
Foetal growth restriction 12.98 9.66 50 213059 9330 90406008
Bladder disorder 12.98 9.66 55 213054 10717 90404621
Unresponsive to stimuli 12.97 9.66 142 212967 37979 90377359
Pneumonia bacterial 12.93 9.66 62 213047 12728 90402610
Torsade de pointes 12.84 9.66 70 213039 15112 90400226
Immune-mediated enterocolitis 12.82 9.66 32 213077 4725 90410613
Tachypnoea 12.82 9.66 90 213019 21219 90394119
Incision site pain 12.79 9.66 16 213093 1362 90413976
Pre-eclampsia 12.74 9.66 5 213104 11043 90404295
Ventricular fibrillation 12.73 9.66 66 213043 13978 90401360
Cor pulmonale chronic 12.69 9.66 8 213101 270 90415068
Subclavian artery thrombosis 12.64 9.66 7 213102 185 90415153
Intra-abdominal haematoma 12.60 9.66 20 213089 2124 90413214
Colitis ischaemic 12.59 9.66 60 213049 12286 90403052
Staphylococcus test positive 12.53 9.66 30 213079 4315 90411023
Escherichia sepsis 12.52 9.66 36 213073 5780 90409558
Lip erosion 12.50 9.66 15 213094 1223 90414115
Laboratory test abnormal 12.49 9.66 152 212957 41702 90373636
Aortic valve calcification 12.48 9.66 11 213098 623 90414715
Blood pressure abnormal 12.43 9.66 84 213025 19561 90395777
Rehabilitation therapy 12.42 9.66 19 213090 1955 90413383
Haematotoxicity 12.41 9.66 7 213102 12528 90402810
Peripheral swelling 12.35 9.66 821 212288 412285 90003053
Productive cough 12.32 9.66 252 212857 76811 90338527
Electrocardiogram QT prolonged 12.28 9.66 239 212870 72217 90343121
Immunodeficiency 12.27 9.66 56 213053 43178 90372160
Sinus bradycardia 12.27 9.66 75 213034 16877 90398461
Influenza 12.26 9.66 421 212688 138843 90276495
Catheter site erythema 12.24 9.66 32 213077 4862 90410476
Oral papilloma 12.23 9.66 5 213104 65 90415273
Product administration error 12.23 9.66 105 213004 26318 90389020
Haemorrhage intracranial 12.22 9.66 69 213040 15093 90400245
Pelvic fracture 12.09 9.66 69 213040 15150 90400188
Cholecystitis 12.09 9.66 75 213034 16965 90398373
Pulmonary arterial wedge pressure increased 12.07 9.66 9 213100 401 90414937
Drug interaction 12.06 9.66 779 212330 275674 90139664
Serotonin syndrome 12.04 9.66 47 213062 37840 90377498
Intestinal obstruction 12.04 9.66 137 212972 36994 90378344
Brain oedema 12.01 9.66 76 213033 17309 90398029
Anhedonia 11.99 9.66 56 213053 11375 90403963
Infusion site infection 11.92 9.66 22 213087 2638 90412700
Intentional product misuse 11.90 9.66 144 212965 89460 90325878
Electrocardiogram U-wave abnormality 11.85 9.66 4 213105 29 90415309
Acute sinusitis 11.84 9.66 29 213080 4232 90411106
Blood urea decreased 11.82 9.66 22 213087 2656 90412682
Panniculitis 11.76 9.66 10 213099 14448 90400890
Squamous cell carcinoma 11.73 9.66 51 213058 10050 90405288
Cerebral ventricular rupture 11.69 9.66 7 213102 215 90415123
Vitamin D deficiency 11.67 9.66 76 213033 17480 90397858
Gastric haemorrhage 11.64 9.66 40 213069 7063 90408275
Vomiting 11.61 9.66 2064 211045 786229 89629109
Hyperbilirubinaemia 11.61 9.66 64 213045 13872 90401466
Shock 11.61 9.66 111 212998 28667 90386671
Sinoatrial block 11.53 9.66 13 213096 992 90414346
Transplant evaluation 11.50 9.66 15 213094 1331 90414007
Blood pressure fluctuation 11.50 9.66 74 213035 52339 90362999
Impaired gastric emptying 11.47 9.66 60 213049 12749 90402589
Tricuspid valve incompetence 11.47 9.66 73 213036 16658 90398680
Renal tubular acidosis 11.47 9.66 20 213089 2295 90413043
Intensive care unit acquired weakness 11.46 9.66 13 213096 998 90414340
Haemorrhagic arteriovenous malformation 11.43 9.66 6 213103 142 90415196
Transplant rejection 11.43 9.66 8 213101 12750 90402588
Bronchiectasis 11.37 9.66 22 213087 22308 90393030
Procedural complication 11.34 9.66 35 213074 5843 90409495
Hepatocellular injury 11.34 9.66 111 212998 28847 90386491
Cardiac valve disease 11.28 9.66 30 213079 4605 90410733
Abortion induced 11.26 9.66 7 213102 11881 90403457
Therapeutic response shortened 11.26 9.66 23 213086 22856 90392482
Cardiac aneurysm 11.25 9.66 13 213096 1019 90414319
Anterior chamber disorder 11.24 9.66 6 213103 147 90415191
Pneumoperitoneum 11.21 9.66 17 213092 1736 90413602
Retinal ischaemia 11.15 9.66 9 213100 451 90414887
Colour blindness 11.14 9.66 8 213101 336 90415002
Mitral valve disease 11.13 9.66 21 213088 2561 90412777
Catheter site cellulitis 11.12 9.66 8 213101 337 90415001
Creatinine renal clearance decreased 11.11 9.66 17 213092 18882 90396456
Device difficult to use 11.05 9.66 15 213094 17510 90397828
Abortion incomplete complicated 11.03 9.66 3 213106 9 90415329
Haemorrhagic stroke 11.01 9.66 37 213072 6459 90408879
Pneumonia fungal 11.00 9.66 39 213070 6992 90408346
Early satiety 10.98 9.66 15 213094 1392 90413946
Renal tubular necrosis 10.92 9.66 65 213044 14490 90400848
Refusal of treatment by patient 10.92 9.66 34 213075 5704 90409634
Serratia test positive 10.90 9.66 4 213105 38 90415300
Diastolic dysfunction 10.90 9.66 40 213069 7293 90408045
Retroperitoneal haemorrhage 10.82 9.66 23 213086 3057 90412281
Abdominal tenderness 10.77 9.66 47 213062 9277 90406061
Skin discolouration 10.76 9.66 155 212954 44160 90371178
Hepatic cirrhosis 10.71 9.66 96 213013 63157 90352181
Aortic stenosis 10.66 9.66 36 213073 6300 90409038
Ischaemia 10.66 9.66 32 213077 5263 90410075
Renal impairment 10.66 9.66 324 212785 105097 90310241
Abdominal wall haematoma 10.61 9.66 24 213085 3328 90412010
Soft tissue infection 10.60 9.66 22 213087 2875 90412463
Peritonitis 10.58 9.66 81 213028 19624 90395714
Catheter site scab 10.58 9.66 7 213102 257 90415081
Peripheral sensorimotor neuropathy 10.57 9.66 18 213091 2027 90413311
Embolic stroke 10.57 9.66 27 213082 4045 90411293
Movement disorder 10.55 9.66 34 213075 28985 90386353
Ecchymosis 10.54 9.66 57 213052 12266 90403072
Blood aldosterone abnormal 10.47 9.66 4 213105 43 90415295
Atrial enlargement 10.41 9.66 8 213101 373 90414965
Bladder outlet obstruction 10.37 9.66 3 213106 12 90415326
Normocytic anaemia 10.36 9.66 22 213087 2922 90412416
Ischaemic skin ulcer 10.30 9.66 4 213105 45 90415293
Catheter culture positive 10.27 9.66 6 213103 176 90415162
Leukoplakia oral 10.25 9.66 7 213102 271 90415067
Pickwickian syndrome 10.25 9.66 8 213101 382 90414956
Tachycardia 10.20 9.66 461 212648 157212 90258126
Lymphangiectasia intestinal 10.15 9.66 4 213105 47 90415291
Blood pressure systolic increased 10.12 9.66 88 213021 58257 90357081
Differentiation syndrome 10.10 9.66 14 213095 1317 90414021
Cardiopulmonary failure 10.08 9.66 27 213082 4161 90411177
Magnesium metabolism disorder 10.07 9.66 4 213105 48 90415290
Product distribution issue 10.07 9.66 25 213084 3680 90411658
Electrocardiogram Q wave abnormal 10.06 9.66 6 213103 183 90415155
Eosinophilia 10.04 9.66 107 213002 28426 90386912
Vascular pseudoaneurysm 10.03 9.66 16 213093 1707 90413631
Dystonia 10.01 9.66 15 213094 16804 90398534
Renin decreased 9.98 9.66 5 213104 107 90415231
Polymyalgia rheumatica 9.94 9.66 30 213079 4947 90410391
Affect lability 9.91 9.66 17 213092 18046 90397292
Injection site pruritus 9.88 9.66 80 213029 53754 90361584
Hypotonia 9.88 9.66 53 213056 11373 90403965
Intestinal polyp 9.87 9.66 15 213094 1534 90413804
Multiple-drug resistance 9.86 9.66 3 213106 7773 90407565
Vulvovaginal mycotic infection 9.86 9.66 35 213074 6279 90409059
Gallbladder disorder 9.86 9.66 80 213029 19723 90395615
Renal cyst 9.82 9.66 58 213051 12892 90402446
Dry skin 9.81 9.66 274 212835 87799 90327539
Pulse pressure decreased 9.80 9.66 6 213103 192 90415146
Electrocardiogram ST segment abnormal 9.80 9.66 13 213096 1173 90414165
Cardioversion 9.79 9.66 14 213095 1356 90413982
Dermal cyst 9.79 9.66 18 213091 2153 90413185
Urinary incontinence 9.77 9.66 133 212976 37433 90377905
Pneumonitis 9.75 9.66 152 212957 44018 90371320
Ischaemic cardiomyopathy 9.75 9.66 20 213089 2593 90412745
Varices oesophageal 9.75 9.66 25 213084 3754 90411584
Aortic valve incompetence 9.74 9.66 36 213073 6588 90408750
Blood magnesium abnormal 9.72 9.66 10 213099 687 90414651
Paratracheal lymphadenopathy 9.72 9.66 4 213105 53 90415285
Adult failure to thrive 9.69 9.66 6 213103 196 90415142

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Drug ineffective 469.49 10.26 720 125903 629477 41865235
Hypokalaemia 296.66 10.26 657 125966 71064 42423648
Hyperkalaemia 237.94 10.26 648 125975 79810 42414902
Drug abuse 197.91 10.26 36 126587 104735 42389977
Cardiac failure congestive 178.50 10.26 610 126013 84992 42409720
Off label use 161.03 10.26 1175 125448 637160 41857552
Acute kidney injury 151.27 10.26 1711 124912 365626 42129086
Toxicity to various agents 150.85 10.26 282 126341 228854 42265858
Cardiac failure 146.90 10.26 668 125955 106188 42388524
Oedema peripheral 138.12 10.26 781 125842 135295 42359417
Atrial fibrillation 136.98 10.26 794 125829 138799 42355913
Toxic anterior segment syndrome 106.34 10.26 61 126562 1355 42493357
Cardiogenic shock 106.20 10.26 288 126335 35352 42459360
Ventricular fibrillation 105.84 10.26 259 126364 29864 42464848
Appendicolith 103.33 10.26 161 126462 13295 42481417
Anaemia 96.58 10.26 1263 125360 279015 42215697
Therapeutic product effect incomplete 94.85 10.26 46 126577 70893 42423819
Dyspnoea 94.22 10.26 1840 124783 440781 42053931
Treatment failure 92.67 10.26 35 126588 62589 42432123
Dehydration 90.85 10.26 726 125897 141041 42353671
Hypotension 90.01 10.26 1164 125459 256467 42238245
Blood potassium decreased 87.87 10.26 190 126433 20194 42474518
Abdominal distension 82.34 10.26 426 126197 71309 42423403
Ascites 81.32 10.26 359 126264 56319 42438393
Suicide attempt 76.63 10.26 21 126602 46079 42448633
International normalised ratio increased 74.40 10.26 312 126311 47856 42446856
Asthenia 74.39 10.26 1209 125414 279584 42215128
Appendicitis 72.15 10.26 177 126446 20436 42474276
Hypervolaemia 70.01 10.26 188 126435 22937 42471775
Chronic obstructive pulmonary disease 69.81 10.26 371 126252 62743 42431969
Fluid retention 69.07 10.26 229 126394 31390 42463322
Blood phosphorus increased 67.38 10.26 128 126495 12397 42482315
Sepsis 63.49 10.26 886 125737 198448 42296264
Hypophosphataemia 62.13 10.26 169 126454 20776 42473936
Pneumonia 61.34 10.26 1664 124959 420485 42074227
Drug ineffective for unapproved indication 60.09 10.26 31 126592 46132 42448580
Right ventricular failure 59.45 10.26 104 126519 9451 42485261
Hyperphosphataemia 58.10 10.26 123 126500 12881 42481831
Hyponatraemia 56.67 10.26 504 126119 100958 42393754
Intentional product use issue 53.04 10.26 82 126541 71751 42422961
Activated partial thromboplastin time prolonged 51.93 10.26 133 126490 15770 42478942
Product use in unapproved indication 49.81 10.26 332 126291 184124 42310588
Myasthenia gravis 48.65 10.26 131 126492 16006 42478706
Pulmonary arterial hypertension 48.61 10.26 99 126524 10088 42484624
Bacterial infection 46.54 10.26 185 126438 27694 42467018
Pulmonary hypertension 46.49 10.26 165 126458 23404 42471308
Gastrointestinal haemorrhage 46.38 10.26 469 126154 97257 42397455
Rheumatoid arthritis 46.26 10.26 35 126588 42405 42452307
Gout 45.90 10.26 185 126438 27870 42466842
Aortic stenosis 45.36 10.26 88 126535 8657 42486055
Sedation 45.13 10.26 17 126606 30458 42464254
Arthralgia 44.75 10.26 392 126231 204846 42289866
Cytokine release syndrome 44.70 10.26 255 126368 44272 42450440
Drug resistance 44.57 10.26 23 126600 34225 42460487
Sleep disorder therapy 44.15 10.26 76 126547 6818 42487894
Suicidal ideation 42.69 10.26 48 126575 48113 42446599
General physical health deterioration 41.35 10.26 655 125968 150591 42344121
Plasma cell myeloma 41.09 10.26 262 126361 47316 42447396
Analgesic therapy 40.57 10.26 71 126552 6453 42488259
Spinal muscular atrophy 39.73 10.26 21 126602 395 42494317
Foetal exposure during pregnancy 38.91 10.26 50 126573 47261 42447451
Acute respiratory failure 38.65 10.26 222 126401 38636 42456076
Psoriasis 37.32 10.26 54 126569 48550 42446162
Fall 36.69 10.26 934 125689 233586 42261126
Incision site pain 36.30 10.26 36 126587 1867 42492845
Loss of personal independence in daily activities 35.70 10.26 58 126565 49758 42444954
Tachypnoea 35.56 10.26 143 126480 21519 42473193
Injection site pain 35.46 10.26 74 126549 57724 42436988
Myelosuppression 35.13 10.26 41 126582 40420 42454292
Supraventricular extrasystoles 35.12 10.26 51 126572 3955 42490757
Drug therapy 34.07 10.26 65 126558 6315 42488397
Intentional overdose 34.06 10.26 63 126560 51393 42443319
Aggression 33.97 10.26 49 126574 44114 42450598
Urticaria 33.78 10.26 110 126513 73926 42420786
Toxic epidermal necrolysis 33.59 10.26 163 126460 26587 42468125
Iron deficiency 33.55 10.26 90 126533 10971 42483741
Drug dependence 33.00 10.26 23 126600 29071 42465641
Antacid therapy 32.86 10.26 54 126569 4663 42490049
Serotonin syndrome 32.69 10.26 18 126605 25827 42468885
Alveolar lung disease 32.30 10.26 19 126604 443 42494269
Oedema 32.00 10.26 264 126359 51737 42442975
Blood creatinine increased 31.81 10.26 481 126142 109522 42385190
Blood lactic acid 31.73 10.26 17 126606 329 42494383
Stress 31.37 10.26 232 126391 43980 42450732
Blood urea increased 31.09 10.26 185 126438 32608 42462104
Blood uric acid increased 30.79 10.26 109 126514 15438 42479274
Headache 30.43 10.26 514 126109 238855 42255857
Anticoagulant therapy 30.37 10.26 51 126572 4484 42490228
Obstructive airways disorder 30.23 10.26 18 126605 24741 42469971
Mental status changes 29.88 10.26 221 126402 41894 42452818
Incorrect route of product administration 29.73 10.26 147 126476 24158 42470554
Foetal disorder 29.56 10.26 25 126598 1054 42493658
Faecal volume decreased 29.43 10.26 14 126609 208 42494504
Pruritus 29.27 10.26 390 126233 188381 42306331
Intentional self-injury 29.17 10.26 5 126618 15197 42479515
Multiple organ dysfunction syndrome 29.10 10.26 427 126196 96608 42398104
Cardiac failure chronic 29 10.26 78 126545 9523 42485189
Sleep disorder due to a general medical condition 28.91 10.26 8 126615 17445 42477267
Pulmonary interstitial emphysema syndrome 28.85 10.26 19 126604 544 42494168
Therapeutic product effect decreased 28.60 10.26 45 126578 39105 42455607
Ventricular tachycardia 28.50 10.26 170 126453 29990 42464722
Rash 28.08 10.26 618 126005 276336 42218376
Diaphragmatic spasm 27.44 10.26 11 126612 105 42494607
Inappropriate schedule of product administration 27.18 10.26 170 126453 95732 42398980
Blood chloride decreased 26.99 10.26 46 126577 4093 42490619
Hypomagnesaemia 26.55 10.26 160 126463 28328 42466384
Swelling 26.31 10.26 264 126359 54621 42440091
Hyperlipidaemia 26.22 10.26 130 126493 21386 42473326
Lung infiltration 25.94 10.26 96 126527 13893 42480819
Therapeutic response decreased 25.68 10.26 44 126579 36968 42457744
Cataract operation complication 25.66 10.26 10 126613 88 42494624
Meningitis aseptic 25.60 10.26 47 126576 4435 42490277
Oropharyngeal pain 25.59 10.26 55 126568 42455 42452257
Product use issue 25.58 10.26 129 126494 76622 42418090
Therapy partial responder 25.24 10.26 14 126609 20007 42474705
Stoma closure 25.11 10.26 14 126609 294 42494418
Cardiorenal syndrome 25.10 10.26 21 126602 872 42493840
Generalised oedema 24.98 10.26 101 126522 15235 42479477
Drug reaction with eosinophilia and systemic symptoms 24.87 10.26 55 126568 42020 42452692
Neutropenia neonatal 24.55 10.26 21 126602 899 42493813
Renal phospholipidosis 24.30 10.26 11 126612 145 42494567
Motor neurone disease 24.20 10.26 17 126606 542 42494170
Ventricular extrasystoles 24.09 10.26 91 126532 13299 42481413
Glomerular filtration rate 23.70 10.26 10 126613 110 42494602
Blood calcium increased 22.89 10.26 66 126557 8388 42486324
Haematotoxicity 22.48 10.26 3 126620 10982 42483730
Heparin-induced thrombocytopenia 22.40 10.26 56 126567 6541 42488171
Erythema 22.28 10.26 211 126412 108582 42386130
Hypernatraemia 22.21 10.26 73 126550 9959 42484753
Peritoneal haematoma 22.00 10.26 9 126614 91 42494621
Haemoglobin decreased 21.99 10.26 532 126091 131939 42362773
Cardiomyopathy 21.96 10.26 114 126509 19096 42475616
Blood cholesterol increased 21.70 10.26 145 126478 26596 42468116
Therapeutic response shortened 21.02 10.26 7 126616 13547 42481165
Cytomegalovirus infection 20.98 10.26 40 126583 32266 42462446
Psychotic disorder 20.93 10.26 34 126589 29174 42465538
Increased bronchial secretion 20.76 10.26 30 126593 2316 42492396
Thrombosis 20.74 10.26 302 126321 68209 42426503
Arthropathy 20.70 10.26 35 126588 29562 42465150
Prothrombin time prolonged 20.16 10.26 68 126555 9401 42485311
Atrial flutter 20.16 10.26 103 126520 17148 42477564
Joint swelling 20.09 10.26 119 126504 67903 42426809
Diarrhoea 19.95 10.26 1608 125015 459241 42035471
Pneumococcal sepsis 19.77 10.26 23 126600 1432 42493280
Puncture site haematoma 19.77 10.26 10 126613 171 42494541
Dry mouth 19.68 10.26 193 126430 39686 42455026
Haemoglobin increased 19.61 10.26 46 126577 5160 42489552
Blood pressure fluctuation 19.58 10.26 31 126592 26877 42467835
Lower respiratory tract infection bacterial 19.56 10.26 15 126608 549 42494163
Pleural effusion 19.52 10.26 401 126222 96765 42397947
Nephropathy toxic 19.51 10.26 13 126610 16825 42477887
Drug interaction 19.37 10.26 625 125998 266374 42228338
Hepatotoxicity 19.28 10.26 28 126595 25139 42469573
Electrolyte imbalance 19.22 10.26 101 126522 17000 42477712
No adverse event 19.20 10.26 56 126567 38965 42455747
Ulcer 19.09 10.26 98 126525 16343 42478369
Hypovolaemia 18.99 10.26 76 126547 11409 42483303
Constipation 18.90 10.26 623 126000 161668 42333044
Procalcitonin decreased 18.80 10.26 11 126612 254 42494458
Drug-induced liver injury 18.77 10.26 55 126568 38218 42456494
Anxiety 18.70 10.26 244 126379 118316 42376396
Right ventricular dysfunction 18.69 10.26 22 126601 1387 42493325
Disease complication 18.56 10.26 33 126590 3037 42491675
Anaphylactic reaction 18.47 10.26 65 126558 42678 42452034
Polyneuropathy 18.35 10.26 17 126606 18644 42476068
Eosinophil percentage decreased 18.34 10.26 11 126612 266 42494446
Cardiac output decreased 18.22 10.26 19 126604 1046 42493666
Blood loss anaemia 18.21 10.26 67 126556 9669 42485043
Blood creatine decreased 18.20 10.26 11 126612 270 42494442
Atrial enlargement 18.16 10.26 16 126607 713 42493999
Skin pressure mark 17.82 10.26 7 126616 63 42494649
Vasculitis 17.80 10.26 17 126606 18377 42476335
Blood bilirubin increased 17.79 10.26 198 126425 42054 42452658
Dyspnoea exertional 17.60 10.26 227 126396 49921 42444791
Bradycardia 17.57 10.26 354 126269 85130 42409582
Dystonia 17.54 10.26 8 126615 12782 42481930
Arthritis 17.50 10.26 65 126558 42000 42452712
Electrocardiogram T wave amplitude decreased 17.44 10.26 12 126611 370 42494342
Hepatic cytolysis 17.44 10.26 138 126485 26706 42468006
Angioedema 17.43 10.26 66 126557 42411 42452301
Total lung capacity decreased 17.40 10.26 35 126588 3535 42491177
Sensory integrative dysfunction 17.36 10.26 6 126617 36 42494676
Insomnia 17.34 10.26 247 126376 118006 42376706
Bronchial disorder 17.19 10.26 21 126602 1377 42493335
Nightmare 17.11 10.26 30 126593 24982 42469730
Lymphadenopathy 17.06 10.26 47 126576 33318 42461394
N-terminal prohormone brain natriuretic peptide increased 17.00 10.26 34 126589 3419 42491293
Cardiac disorder 16.97 10.26 221 126402 48711 42446001
Cellulitis 16.91 10.26 267 126356 61318 42433394
Rectal haemorrhage 16.76 10.26 223 126400 49383 42445329
Extrasystoles 16.74 10.26 38 126585 4171 42490541
Lymphadenectomy 16.64 10.26 13 126610 489 42494223
Peri-implantitis 16.58 10.26 8 126615 123 42494589
Cardioactive drug level increased 16.54 10.26 23 126600 1714 42492998
International normalised ratio fluctuation 16.46 10.26 20 126603 1304 42493408
Cor pulmonale 16.42 10.26 16 126607 812 42493900
Scrotal oedema 16.39 10.26 24 126599 1875 42492837
Atelectasis 16.33 10.26 106 126517 19255 42475457
Poisoning 16.17 10.26 12 126611 14687 42480025
Psoriatic arthropathy 16.14 10.26 31 126592 24936 42469776
Exercise tolerance decreased 16.08 10.26 47 126576 6019 42488693
End stage renal disease 16.07 10.26 94 126529 16464 42478248
Injection site swelling 16.06 10.26 16 126607 16957 42477755
Blood pressure increased 15.99 10.26 210 126413 101718 42392994
Neurological symptom 15.78 10.26 5 126618 9986 42484726
Cerebellar ischaemia 15.75 10.26 8 126615 138 42494574
Troponin T increased 15.68 10.26 29 126594 2751 42491961
Emotional disorder of childhood 15.68 10.26 6 126617 50 42494662
Neuralgia 15.66 10.26 130 126493 25517 42469195
Chronic left ventricular failure 15.63 10.26 15 126608 747 42493965
Tendonitis 15.54 10.26 5 126618 9889 42484823
Hyperhidrosis 15.50 10.26 183 126440 90329 42404383
Post transplant lymphoproliferative disorder 15.44 10.26 4 126619 9116 42485596
Schizophrenia 15.43 10.26 6 126617 10544 42484168
Therapy non-responder 15.42 10.26 94 126529 53265 42441447
Blood albumin decreased 15.32 10.26 88 126535 15314 42479398
Cytomegalovirus infection reactivation 15.31 10.26 7 126616 11171 42483541
Product residue present 15.24 10.26 29 126594 2812 42491900
Blood immunoglobulin M abnormal 15.22 10.26 7 126616 96 42494616
Depressed mood 15.14 10.26 29 126594 23355 42471357
Blood immunoglobulin G abnormal 15.03 10.26 7 126616 99 42494613
Hypersensitivity 14.96 10.26 140 126483 72230 42422482
Ischaemic cardiomyopathy 14.92 10.26 48 126575 6474 42488238
Aspergillus infection 14.91 10.26 15 126608 15822 42478890
Product dose omission issue 14.89 10.26 347 126276 154018 42340694
Platelet count decreased 14.87 10.26 527 126096 138054 42356658
Respiratory failure 14.69 10.26 491 126132 127641 42367071
Injection site reaction 14.67 10.26 15 126608 15706 42479006
Drug eruption 14.61 10.26 29 126594 23046 42471666
Metabolic alkalosis 14.57 10.26 24 126599 2077 42492635
Therapeutic product effect prolonged 14.54 10.26 10 126613 308 42494404
Type IIa hyperlipidaemia 14.54 10.26 10 126613 308 42494404
N-terminal prohormone brain natriuretic peptide abnormal 14.50 10.26 9 126614 232 42494480
Congestive cardiomyopathy 14.50 10.26 58 126565 8706 42486006
Heparin-induced thrombocytopenia test 14.43 10.26 8 126615 166 42494546
Mobility decreased 14.39 10.26 55 126568 35251 42459461
Hypoparathyroidism 14.36 10.26 14 126609 711 42494001
Frequent bowel movements 14.35 10.26 26 126597 21381 42473331
Seizure 14.29 10.26 262 126361 120299 42374413
Sopor 14.24 10.26 11 126612 13191 42481521
Resuscitation 14.24 10.26 22 126601 1803 42492909
Sputum increased 14.22 10.26 30 126593 3133 42491579
Inappropriate antidiuretic hormone secretion 14.10 10.26 17 126606 16524 42478188
Syringe issue 14.02 10.26 4 126619 8552 42486160
Haematocrit decreased 13.98 10.26 162 126461 34746 42459966
Red blood cell sedimentation rate increased 13.93 10.26 6 126617 9918 42484794
Hypertransaminasaemia 13.91 10.26 5 126618 9222 42485490
Femoral artery aneurysm 13.74 10.26 8 126615 183 42494529
Mucosal inflammation 13.74 10.26 88 126535 49286 42445426
COVID-19 13.73 10.26 252 126371 115696 42379016
Blood test abnormal 13.67 10.26 75 126548 12831 42481881
Leukopenia 13.63 10.26 149 126474 74597 42420115
Migraine 13.60 10.26 35 126588 25379 42469333
Wheezing 13.58 10.26 101 126522 54680 42440032
Catheter management 13.50 10.26 16 126607 1016 42493696
Wrong technique in product usage process 13.45 10.26 73 126550 42562 42452150
Blood gases abnormal 13.42 10.26 10 126613 350 42494362
Hepatic function abnormal 13.30 10.26 94 126529 51473 42443239
Aortic valve calcification 13.28 10.26 12 126611 553 42494159
Shoshin beriberi 13.26 10.26 6 126617 79 42494633
Pulmonary oedema 13.16 10.26 227 126396 53045 42441667
Substance abuse 13.13 10.26 5 126618 8900 42485812
Arrhythmia supraventricular 13.08 10.26 19 126604 1474 42493238
Haematoma 13.04 10.26 134 126489 27889 42466823
Intercepted product preparation error 12.98 10.26 3 126620 7386 42487326
Hallucination, auditory 12.97 10.26 15 126608 14849 42479863
Myalgia 12.94 10.26 204 126419 95876 42398836
Drug withdrawal syndrome 12.87 10.26 28 126595 21521 42473191
BK virus infection 12.84 10.26 5 126618 8779 42485933
Neuroleptic malignant syndrome 12.74 10.26 28 126595 21444 42473268
Blood magnesium decreased 12.67 10.26 51 126572 7675 42487037
Vascular purpura 12.58 10.26 23 126600 2163 42492549
Bronchopulmonary aspergillosis allergic 12.55 10.26 36 126587 4562 42490150
Systemic infection 12.54 10.26 39 126584 5166 42489546
Drug level decreased 12.54 10.26 7 126616 9970 42484742
Alkalosis 12.43 10.26 7 126616 150 42494562
Hypoxia 12.41 10.26 283 126340 69503 42425209
Paranoia 12.40 10.26 14 126609 14012 42480700
C-reactive protein abnormal 12.38 10.26 6 126617 9255 42485457
Limited symptom panic attack 12.36 10.26 5 126618 49 42494663
Miosis 12.36 10.26 13 126610 13433 42481279
Mucormycosis 12.35 10.26 3 126620 7140 42487572
Sinusitis 12.30 10.26 86 126537 47206 42447506
Hospice care 12.26 10.26 54 126569 8459 42486253
Transient aphasia 12.19 10.26 12 126611 617 42494095
Blood thyroid stimulating hormone increased 12.16 10.26 39 126584 5253 42489459
Red blood cells urine positive 12.16 10.26 21 126602 1889 42492823
Blood pressure diastolic decreased 12.03 10.26 8 126615 10367 42484345
Death 12.00 10.26 1586 125037 469599 42025113
Renal atrophy 11.99 10.26 17 126606 1290 42493422
Breath sounds abnormal 11.96 10.26 69 126554 12024 42482688
Salivary hypersecretion 11.95 10.26 9 126614 10934 42483778
Oesophageal carcinoma 11.91 10.26 7 126616 9689 42485023
Aspiration pleural cavity 11.87 10.26 14 126609 885 42493827
Extrapyramidal disorder 11.86 10.26 19 126604 16393 42478319
Cerebral infarction 11.79 10.26 50 126573 31119 42463593
Overdose 11.78 10.26 231 126392 105033 42389679
Pathogen resistance 11.78 10.26 10 126613 11440 42483272
Accidental exposure to product 11.77 10.26 27 126596 20366 42474346
Withdrawal syndrome 11.75 10.26 16 126607 14759 42479953
Septic shock 11.73 10.26 356 126267 91316 42403396
Eye pruritus 11.70 10.26 10 126613 11402 42483310
Lymphocyte count decreased 11.56 10.26 130 126493 27679 42467033
Respiratory alkalosis 11.45 10.26 23 126600 2321 42492391
Product substitution issue 11.44 10.26 10 126613 11280 42483432
Enterobacter pneumonia 11.43 10.26 11 126612 550 42494162
Immune effector cell-associated neurotoxicity syndrome 11.41 10.26 57 126566 9404 42485308
Agitation 11.41 10.26 129 126494 64185 42430527
Stasis dermatitis 11.40 10.26 16 126607 1202 42493510
Depression 11.39 10.26 248 126375 111115 42383597
Dyskinesia 11.38 10.26 38 126585 25352 42469360
Metabolic encephalopathy 11.37 10.26 38 126585 5227 42489485
Irritability 11.35 10.26 44 126579 28084 42466628
Pseudolymphoma 11.33 10.26 12 126611 673 42494039
Torsade de pointes 11.24 10.26 53 126570 8541 42486171
Pulmonary valve replacement 11.19 10.26 3 126620 6 42494706
Gastrointestinal vascular malformation haemorrhagic 11.14 10.26 13 126610 812 42493900
Blood pressure systolic increased 11.12 10.26 44 126579 27924 42466788
Mania 11.11 10.26 9 126614 10538 42484174
Pneumocystis jirovecii pneumonia 11.08 10.26 38 126585 25143 42469569
Systemic lupus erythematosus 11.07 10.26 7 126616 9317 42485395
Cognitive disorder 11.06 10.26 58 126565 34114 42460598
Blood urea decreased 11.04 10.26 17 126606 1389 42493323
Altered state of consciousness 11.03 10.26 47 126576 29212 42465500
Bacteroides infection 11.02 10.26 24 126599 2563 42492149
Musculoskeletal stiffness 11.00 10.26 114 126509 57651 42437061
Diffuse alveolar damage 10.98 10.26 24 126599 2568 42492144
Rash pruritic 10.89 10.26 57 126566 33546 42461166
Respiratory tract infection bacterial 10.88 10.26 20 126603 1889 42492823
Pulmonary alveolar haemorrhage 10.85 10.26 17 126606 14799 42479913
Coagulation factor VII level decreased 10.80 10.26 6 126617 125 42494587
Atrial septal defect 10.78 10.26 5 126618 7914 42486798
Troponin increased 10.78 10.26 95 126528 18967 42475745
Impaired work ability 10.77 10.26 12 126611 12079 42482633
Cardiac pacemaker evaluation 10.76 10.26 6 126617 126 42494586
Iron deficiency anaemia 10.76 10.26 71 126552 12968 42481744
Prostate cancer 10.74 10.26 83 126540 44560 42450152
Unevaluable event 10.71 10.26 152 126471 34136 42460576
Anaphylactic shock 10.68 10.26 35 126588 23482 42471230
Cardioactive drug level decreased 10.59 10.26 5 126618 73 42494639
Stomatitis 10.56 10.26 97 126526 50232 42444480
Clostridium difficile colitis 10.55 10.26 103 126520 21149 42473563
Right atrial pressure increased 10.55 10.26 6 126617 131 42494581
Pantoea agglomerans infection 10.53 10.26 5 126618 74 42494638
Febrile neutropenia 10.41 10.26 662 125961 185041 42309671
Cortical visual impairment 10.38 10.26 4 126619 34 42494678
Lip swelling 10.38 10.26 26 126597 19027 42475685
Ischaemic cerebral infarction 10.37 10.26 18 126605 1625 42493087
Hypertrophy 10.34 10.26 10 126613 503 42494209
Drug chemical incompatibility 10.33 10.26 3 126620 9 42494703
Congenital hiatus hernia 10.32 10.26 41 126582 6133 42488579
Catheter site infection 10.29 10.26 26 126597 3057 42491655
Lactobacillus test positive 10.28 10.26 4 126619 35 42494677
Shock haemorrhagic 10.28 10.26 83 126540 16159 42478553
Pleuritic pain 10.27 10.26 45 126578 7032 42487680
Mood altered 10.26 10.26 10 126613 10708 42484004

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Drug ineffective 794.87 9.97 1718 283577 1518822 108785182
Hypokalaemia 792.91 9.97 1569 283726 180879 110123125
Hyperkalaemia 789.66 9.97 1325 283970 134471 110169533
Acute kidney injury 590.82 9.97 3210 282085 632220 109671784
Hand deformity 530.99 9.97 6 285289 218500 110085504
Pemphigus 530.35 9.97 4 285291 214566 110089438
Cardiac failure congestive 519.54 9.97 1181 284114 149819 110154185
Anaemia 483.55 9.97 2727 282568 544359 109759645
Systemic lupus erythematosus 450.85 9.97 61 285234 254277 110049727
Atrial fibrillation 414.10 9.97 1419 283876 228223 110075781
Duodenal ulcer perforation 410.53 9.97 10 285285 177690 110126314
Helicobacter infection 409.95 9.97 13 285282 181864 110122140
Glossodynia 408.69 9.97 47 285248 221957 110082047
Joint swelling 383.07 9.97 347 284948 442498 109861506
Pericarditis 366.68 9.97 62 285233 219052 110084952
Dehydration 358.45 9.97 1550 283745 277961 110026043
Arthropathy 343.12 9.97 156 285139 287366 110016638
Muscle injury 332.85 9.97 6 285289 140801 110163203
Wound 325.27 9.97 100 285195 234337 110069667
Synovitis 323.51 9.97 151 285144 273941 110030063
Folliculitis 320.09 9.97 31 285264 167622 110136382
Hypervolaemia 317.57 9.97 505 284790 48955 110255049
Cardiac failure 311.95 9.97 1129 284166 186497 110117507
Therapeutic product effect decreased 311.70 9.97 120 285175 244196 110059808
Irritable bowel syndrome 301.63 9.97 35 285260 164180 110139824
Hypotension 297.25 9.97 2339 282956 521510 109782494
Rheumatoid arthritis 295.10 9.97 206 285089 299407 110004597
Sepsis 284.84 9.97 1626 283669 325720 109978284
Treatment failure 277.84 9.97 187 285108 277047 110026957
Alopecia 273.28 9.97 323 284972 364430 109939574
Psoriatic arthropathy 265.70 9.97 88 285207 196673 110107331
Oedema peripheral 263.64 9.97 1598 283697 327062 109976942
Contraindicated product administered 260.34 9.97 159 285136 248108 110055896
Impaired healing 255.29 9.97 94 285201 196623 110107381
Blood potassium decreased 253.84 9.97 481 284814 53633 110250371
Maternal exposure during pregnancy 251.30 9.97 175 285120 254708 110049296
Hepatic enzyme increased 250.31 9.97 275 285020 320617 109983387
Sleep disorder due to general medical condition, insomnia type 247.67 9.97 5 285290 105638 110198366
Pneumonia 247.56 9.97 3394 281901 873320 109430684
Musculoskeletal stiffness 244.50 9.97 217 285078 279605 110024399
Lower respiratory tract infection 243.56 9.97 164 285131 242942 110061062
Dyspnoea 237.74 9.97 4090 281205 1102782 109201222
Drug abuse 236.66 9.97 81 285214 177330 110126674
Pulmonary hypertension 236.08 9.97 472 284823 54748 110249256
Facet joint syndrome 225.34 9.97 5 285290 96823 110207181
Drug intolerance 223.74 9.97 444 284851 406068 109897936
Ill-defined disorder 215.57 9.97 68 285227 156785 110147219
Off label use 214.57 9.97 2662 282633 1497523 108806481
Gastrointestinal haemorrhage 209.78 9.97 915 284380 164603 110139401
Joint range of motion decreased 209.33 9.97 32 285263 121800 110182204
Pulmonary arterial hypertension 208.33 9.97 332 284963 32236 110271768
Hyponatraemia 207.82 9.97 1109 284186 216544 110087460
Abdominal discomfort 207.57 9.97 441 284854 393417 109910587
Lip dry 206.44 9.97 13 285282 100070 110203934
Hypersensitivity 204.14 9.97 463 284832 403535 109900469
Acute respiratory failure 202.66 9.97 536 284759 74724 110229280
C-reactive protein abnormal 201.47 9.97 44 285251 129651 110174353
Right ventricular failure 200.68 9.97 289 285006 25665 110278339
International normalised ratio increased 199.13 9.97 583 284712 86189 110217815
Fibromyalgia 198.76 9.97 96 285199 170813 110133191
Toxicity to various agents 195.69 9.97 613 284682 479942 109824062
Arthralgia 189.08 9.97 1207 284088 778425 109525579
Chronic obstructive pulmonary disease 187.43 9.97 664 284631 108494 110195510
Discomfort 186.93 9.97 167 285128 214540 110089464
Infusion related reaction 186.80 9.97 444 284851 380718 109923286
Intentional product use issue 186.15 9.97 219 285076 247687 110056317
Toxic anterior segment syndrome 185.51 9.97 114 285181 3340 110300664
Liver injury 178.74 9.97 82 285213 150331 110153673
Bursitis 173.81 9.97 59 285236 129859 110174145
Death 171.36 9.97 2641 282654 696228 109607776
Drug hypersensitivity 167.25 9.97 605 284690 453485 109850519
Grip strength decreased 166.61 9.97 10 285285 80164 110223840
Diarrhoea 161.69 9.97 3961 281334 1135544 109168460
Blister 160.09 9.97 211 285084 227165 110076839
Fall 154.60 9.97 2298 282997 601184 109702820
Fluid retention 153.68 9.97 564 284731 93743 110210261
Plasma cell myeloma 152.27 9.97 431 284864 62505 110241499
Urticaria 151.79 9.97 377 284918 318480 109985524
Type 2 diabetes mellitus 151.70 9.97 140 285155 177092 110126912
Inflammation 151.27 9.97 165 285130 193073 110110931
Product use in unapproved indication 150.00 9.97 619 284676 446758 109857246
Ascites 147.02 9.97 550 284745 92258 110211746
Stomatitis 146.17 9.97 298 284997 269944 110034060
Cardiogenic shock 145.95 9.97 400 284895 56938 110247066
Mobility decreased 145.09 9.97 243 285052 237179 110066825
Exposure during pregnancy 144.79 9.97 131 285164 167293 110136711
Renal failure 144.70 9.97 1041 284254 225533 110078471
Respiratory failure 143.73 9.97 1000 284295 214332 110089672
Cytokine release syndrome 141.32 9.97 451 284844 69855 110234149
Product use issue 138.84 9.97 381 284914 311314 109992690
Nasopharyngitis 137.64 9.97 537 284758 393824 109910180
Pleural effusion 136.61 9.97 855 284440 176854 110127150
Wheezing 135.87 9.97 284 285011 254946 110049058
Rash 135.56 9.97 1409 283886 819555 109484449
Osteoarthritis 134.23 9.97 164 285131 182459 110121545
Ventricular fibrillation 131.94 9.97 314 284981 40999 110263005
Night sweats 125.50 9.97 97 285198 133886 110170118
Blepharospasm 123.27 9.97 4 285291 54847 110249157
Live birth 122.25 9.97 17 285278 69467 110234537
Appendicolith 121.00 9.97 166 285129 14089 110289915
Hypoxia 120.21 9.97 655 284640 128860 110175144
Colitis microscopic 113.73 9.97 156 285139 13238 110290766
Constipation 111.71 9.97 1412 283883 356374 109947630
Drug ineffective for unapproved indication 108.95 9.97 65 285230 102773 110201231
Vaginal flatulence 105.47 9.97 143 285152 12001 110292003
Hypophosphataemia 102.52 9.97 249 285046 32933 110271071
Febrile neutropenia 101.38 9.97 1256 284039 315511 109988493
Peripheral venous disease 101.26 9.97 45 285250 84072 110219932
Psoriasis 99.44 9.97 129 285166 139864 110164140
Hypomagnesaemia 99.15 9.97 362 284933 60008 110243996
Asthenia 99.13 9.97 2401 282894 686598 109617406
Blood creatinine increased 97.62 9.97 806 284489 182083 110121921
Onychomadesis 93.96 9.97 6 285289 45657 110258347
Haemoglobin decreased 93.75 9.97 1018 284277 247709 110056295
Swelling 93.54 9.97 527 284768 350514 109953490
Urinary tract infection 92.36 9.97 1265 284030 325017 109978987
Obesity 91.81 9.97 94 285201 113257 110190747
Female genital tract fistula 91.68 9.97 158 285137 16361 110287643
Proctitis 91.46 9.97 160 285135 16767 110287237
Wound infection 91.40 9.97 69 285226 96396 110207608
Dyspnoea exertional 91.05 9.97 518 284777 103542 110200462
Sleep disorder 90.53 9.97 240 285055 198404 110105600
Autoimmune disorder 88.86 9.97 29 285266 65454 110238550
Syncope 88.76 9.97 855 284440 201681 110102323
Injury 88.74 9.97 204 285091 177061 110126943
Radiculopathy 87.13 9.97 169 285126 19167 110284837
Pulmonary fibrosis 86.83 9.97 81 285214 101961 110202043
Glaucoma 86.26 9.97 184 285111 22333 110281671
Gout 86.09 9.97 248 285047 36318 110267686
Bronchitis 85.93 9.97 696 284599 156336 110147668
Sinusitis 85.36 9.97 434 284861 296254 110007750
Nail disorder 85.34 9.97 22 285273 57913 110246091
Pain 84.92 9.97 1848 283447 953107 109350897
Gastrointestinal disorder 84.65 9.97 329 284966 241623 110062381
Blood cholesterol increased 84.40 9.97 223 285072 184562 110119442
Cardiac arrest 83.00 9.97 824 284471 195929 110108075
Coeliac disease 82.36 9.97 8 285287 43179 110260825
Blood urea increased 82.33 9.97 320 284975 54637 110249367
Appendicitis 82.03 9.97 208 285087 28256 110275748
Blood phosphorus increased 81.31 9.97 149 285146 16191 110287813
Therapeutic product effect incomplete 81.09 9.97 300 284995 223505 110080499
Platelet count decreased 80.85 9.97 930 284365 229513 110074491
Road traffic accident 80.44 9.97 95 285200 107303 110196701
Atrial flutter 80.29 9.97 187 285108 24075 110279929
Injection site reaction 80.25 9.97 67 285228 89003 110215001
Activated partial thromboplastin time prolonged 80.24 9.97 178 285117 22190 110281814
Prescribed overdose 80.00 9.97 65 285230 87516 110216488
Macular degeneration 79.55 9.97 174 285121 21485 110282519
Electrolyte imbalance 79.45 9.97 243 285052 36785 110267219
Colitis 78.40 9.97 492 284803 101831 110202173
Rectal haemorrhage 77.85 9.97 553 284742 119280 110184724
Mental status changes 77.49 9.97 395 284900 75727 110228277
Pulmonary embolism 77.24 9.97 870 284425 213604 110090400
Gait inability 76.61 9.97 147 285148 136229 110167775
Lower limb fracture 76.53 9.97 50 285245 75298 110228706
Chronic sinusitis 76.18 9.97 187 285108 24897 110279107
Pregnancy 75.97 9.97 19 285276 51048 110252956
Deep vein thrombosis 74.91 9.97 617 284678 139270 110164734
Haematoma 73.82 9.97 323 284972 58153 110245851
Pulmonary oedema 73.42 9.97 478 284817 100181 110203823
Toxic epidermal necrolysis 72.88 9.97 315 284980 56412 110247592
Hypercholesterolaemia 72.80 9.97 76 285219 90761 110213243
Finger deformity 72.34 9.97 3 285292 33089 110270915
Blood bilirubin increased 70.32 9.97 384 284911 75588 110228416
Abdominal distension 69.38 9.97 724 284571 174379 110129625
Vaginal discharge 69.37 9.97 147 285148 17761 110286243
Cellulitis 68.65 9.97 558 284737 125458 110178546
White blood cell count decreased 68.45 9.97 898 284397 228492 110075512
Red blood cell sedimentation rate increased 68.00 9.97 61 285234 78241 110225763
Suicide attempt 67.70 9.97 101 285194 103293 110200711
Blood loss anaemia 67.56 9.97 146 285149 17879 110286125
Musculoskeletal pain 67.17 9.97 244 285051 182779 110121225
Hip arthroplasty 66.95 9.97 30 285265 55783 110248221
Migraine 66.93 9.97 223 285072 171429 110132575
Thrombocytopenia 66.55 9.97 1267 284028 347618 109956386
Infection 66.17 9.97 606 284689 361594 109942410
Transfusion 66.11 9.97 179 285116 25293 110278711
Bone erosion 65.69 9.97 19 285276 46352 110257652
Taste disorder 64.25 9.97 45 285250 65342 110238662
Device expulsion 63.73 9.97 4 285291 30887 110273117
Hypocalcaemia 63.63 9.97 335 284960 65031 110238973
Hypoaesthesia 63.07 9.97 513 284782 313710 109990294
Hyperphosphataemia 62.91 9.97 134 285161 16247 110287757
Paraesthesia 62.34 9.97 437 284858 276084 110027920
Injection site pain 62.17 9.97 242 285053 177680 110126324
Thrombosis 60.73 9.97 484 284811 108178 110195826
Bradycardia 60.66 9.97 641 284654 154876 110149128
Pneumonia aspiration 60.62 9.97 388 284907 80845 110223159
Therapeutic response decreased 59.62 9.97 98 285197 96401 110207603
Exostosis 59.52 9.97 22 285273 45934 110258070
Suicidal ideation 59.35 9.97 94 285201 93843 110210161
Arthritis 59.16 9.97 227 285068 167359 110136645
Hyperlipidaemia 58.89 9.97 215 285080 35633 110268371
Diverticulitis 58.21 9.97 283 285012 53239 110250765
Onychomycosis 57.97 9.97 14 285281 38517 110265487
Joint stiffness 57.65 9.97 53 285242 67190 110236814
Therapy non-responder 57.54 9.97 210 285085 157097 110146907
Ventricular tachycardia 56.98 9.97 268 285027 49741 110254263
Foot deformity 56.69 9.97 27 285268 48453 110255551
Septic shock 56.69 9.97 639 284656 156889 110147115
Asthma 56.69 9.97 395 284900 249896 110054108
Myasthenia gravis 56.67 9.97 152 285143 21359 110282645
Generalised oedema 56.35 9.97 191 285104 30513 110273491
Sleep disorder therapy 56.02 9.97 82 285213 7389 110296615
Epistaxis 55.93 9.97 548 284747 129824 110174180
Dementia 55.48 9.97 194 285101 31479 110272525
Epilepsy 55.42 9.97 109 285186 100100 110203904
Paraesthesia oral 55.36 9.97 202 285093 33469 110270535
Hyperaldosteronism 55.13 9.97 29 285266 626 110303378
Injection site swelling 55.03 9.97 47 285248 61743 110242261
Drug-induced liver injury 54.74 9.97 145 285150 119922 110184082
Therapy partial responder 54.72 9.97 14 285281 37047 110266957
Respiratory distress 54.53 9.97 334 284961 68540 110235464
Blood alkaline phosphatase increased 54.28 9.97 341 284954 70594 110233410
Sciatica 54.19 9.97 97 285198 92302 110211702
Multiple organ dysfunction syndrome 53.51 9.97 613 284682 151097 110152907
Melaena 52.91 9.97 331 284964 68426 110235578
Clostridium difficile colitis 52.38 9.97 238 285057 43540 110260464
Catheter management 52.19 9.97 56 285239 3679 110300325
Metabolic alkalosis 51.83 9.97 68 285227 5527 110298477
Analgesic therapy 51.82 9.97 78 285217 7206 110296798
Cardiac failure acute 51.64 9.97 158 285137 23920 110280084
Knee arthroplasty 51.31 9.97 55 285240 64893 110239111
Bacterial infection 51.20 9.97 245 285050 45791 110258213
Cholestasis 51.16 9.97 313 284982 64205 110239799
Pancytopenia 51.09 9.97 792 284503 208821 110095183
Lupus-like syndrome 50.40 9.97 21 285274 40771 110263233
Oral candidiasis 50.36 9.97 239 285056 44521 110259483
Encephalopathy 50.30 9.97 370 284925 80685 110223319
Metabolic encephalopathy 50.24 9.97 97 285198 10963 110293041
Cor pulmonale 50.19 9.97 44 285251 2250 110301754
Back injury 50.14 9.97 30 285265 47369 110256635
Intentional self-injury 50.04 9.97 17 285278 37412 110266592
Adverse drug reaction 50.02 9.97 125 285170 105434 110198570
Full blood count decreased 49.80 9.97 189 285106 31910 110272094
Procedural pain 49.19 9.97 202 285093 35363 110268641
Arrhythmia 48.08 9.97 326 284969 69249 110234755
Hypoglycaemia 47.37 9.97 483 284812 115621 110188383
Incision site pain 47.36 9.97 49 285246 3086 110300918
Cardiomegaly 47.25 9.97 174 285121 28956 110275048
Aspartate aminotransferase increased 47.23 9.97 625 284670 159311 110144693
Aortic stenosis 46.93 9.97 104 285191 12955 110291049
Abdominal pain 46.89 9.97 1690 283605 511299 109792705
Loss of personal independence in daily activities 46.87 9.97 213 285082 149807 110154197
Oxygen consumption increased 46.45 9.97 65 285230 5620 110298384
Liver disorder 46.23 9.97 199 285096 142044 110161960
Cerebrovascular accident 45.73 9.97 689 284606 180595 110123409
Cardiac disorder 45.52 9.97 345 284950 75935 110228069
Cardiac failure chronic 45.21 9.97 106 285189 13705 110290299
Malnutrition 45.14 9.97 164 285131 27115 110276889
Tachypnoea 44.79 9.97 211 285084 39184 110264820
Hospice care 44.45 9.97 99 285196 12374 110291630
Hypernatraemia 43.98 9.97 123 285172 17710 110286294
Drug therapy 42.13 9.97 71 285224 7220 110296784
Drug resistance 42.06 9.97 50 285245 56324 110247680
Spinal muscular atrophy 42.01 9.97 21 285274 406 110303598
Vascular device infection 41.82 9.97 115 285180 16397 110287607
Inappropriate schedule of product administration 41.51 9.97 331 284964 203306 110100698
Insomnia 41.48 9.97 667 284628 359923 109944081
Blood potassium increased 40.71 9.97 182 285113 33067 110270937
Prothrombin time prolonged 40.56 9.97 117 285178 17144 110286860
Hepatotoxicity 40.47 9.97 63 285232 63337 110240667
Adverse event 39.95 9.97 145 285150 108664 110195340
Atelectasis 39.83 9.97 194 285101 36518 110267486
Immune effector cell-associated neurotoxicity syndrome 39.49 9.97 105 285190 14677 110289327
Electrocardiogram abnormal 39.41 9.97 122 285173 18587 110285417
Antacid therapy 39.40 9.97 59 285236 5425 110298579
Hyperglycaemia 39.14 9.97 363 284932 84727 110219277
Brain natriuretic peptide increased 38.86 9.97 88 285207 11121 110292883
Cardioactive drug level increased 38.82 9.97 49 285246 3833 110300171
Adverse reaction 38.61 9.97 14 285281 29580 110274424
Injection site erythema 38.33 9.97 120 285175 94056 110209948
Hypoalbuminaemia 38.07 9.97 162 285133 28812 110275192
Troponin increased 38.01 9.97 165 285130 29601 110274403
Lung disorder 37.93 9.97 290 285005 179757 110124247
Unevaluable event 37.69 9.97 272 285023 58955 110245049
Anticoagulant therapy 37.56 9.97 57 285238 5304 110298700
Cataract operation complication 37.13 9.97 17 285278 268 110303736
Pruritus 37.10 9.97 1180 284115 580380 109723624
Product quality issue 37.04 9.97 91 285204 77208 110226796
Left ventricular failure 36.83 9.97 87 285208 11302 110292702
Device related infection 36.73 9.97 200 285095 39319 110264685
Blood cholesterol decreased 36.69 9.97 40 285255 2676 110301328
Obstructive airways disorder 36.54 9.97 39 285256 46110 110257894
Blood magnesium decreased 36.35 9.97 124 285171 19872 110284132
Muscle spasticity 36.24 9.97 24 285271 35891 110268113
Haematocrit decreased 36.12 9.97 293 285002 65824 110238180
Drug tolerance decreased 35.97 9.97 13 285282 27527 110276477
Blood glucose increased 35.94 9.97 510 284785 131986 110172018
Lung infiltration 35.75 9.97 142 285153 24486 110279518
Intentional overdose 35.75 9.97 198 285097 132303 110171701
Product residue present 35.13 9.97 47 285248 3894 110300110
Congestive cardiomyopathy 34.99 9.97 98 285197 14121 110289883
Failure to thrive 34.84 9.97 95 285200 13479 110290525
Contusion 34.59 9.97 410 284885 232951 110071053
Drug eruption 34.56 9.97 53 285242 53606 110250398
Heparin-induced thrombocytopenia 34.51 9.97 85 285210 11339 110292665
Blood pressure fluctuation 34.38 9.97 90 285205 74734 110229270
Peripheral circulatory failure 34.13 9.97 32 285263 1787 110302217
Sleep disorder due to a general medical condition 34.02 9.97 51 285244 52061 110251943
Lymphoedema 33.94 9.97 100 285195 14829 110289175
Hypovolaemia 33.94 9.97 128 285167 21546 110282458
Neuroglycopenia 33.89 9.97 26 285269 1100 110302904
Serotonin syndrome 33.88 9.97 63 285232 59090 110244914
Catheter site infection 33.72 9.97 68 285227 7932 110296072
Disability 33.59 9.97 18 285277 30205 110273799
Subdural haematoma 33.56 9.97 184 285111 36270 110267734
Prescribed underdose 33.42 9.97 74 285221 65100 110238904
Rheumatoid nodule 33.37 9.97 6 285289 20290 110283714
Iron deficiency 33.08 9.97 114 285181 18362 110285642
Ileus 33.07 9.97 162 285133 30567 110273437
Schizophrenia 32.70 9.97 8 285287 21818 110282186
Cardiorenal syndrome 32.69 9.97 32 285263 1886 110302118
Walking aid user 32.48 9.97 12 285283 25063 110278941
Blood uric acid increased 31.95 9.97 125 285170 21404 110282600
Sedation 31.87 9.97 84 285211 69599 110234405
Head injury 31.80 9.97 205 285090 42812 110261192
Blood lactic acid 31.49 9.97 18 285277 460 110303544
Endophthalmitis 31.47 9.97 67 285228 8120 110295884
Dry mouth 31.31 9.97 347 284948 199601 110104403
Laryngitis 31.23 9.97 38 285257 42373 110261631
Tenosynovitis 31.09 9.97 3 285292 16280 110287724
Chronic respiratory failure 30.96 9.97 44 285251 3859 110300145
Therapeutic response shortened 30.90 9.97 19 285276 29564 110274440
Gastric polyps 30.88 9.97 53 285242 5470 110298534
Chronic left ventricular failure 30.67 9.97 26 285269 1270 110302734
Vascular purpura 30.64 9.97 43 285252 3728 110300276
Hypercapnia 30.56 9.97 80 285215 11079 110292925
Chronic kidney disease 30.46 9.97 316 284979 75975 110228029
Shock haemorrhagic 30.29 9.97 145 285150 27102 110276902
Right ventricular dysfunction 30.19 9.97 40 285255 3283 110300721
Myelosuppression 30.03 9.97 133 285162 94207 110209797
Supraventricular extrasystoles 29.81 9.97 65 285230 8008 110295996
Hyperkaliuria 29.72 9.97 13 285282 183 110303821
Pneumonia staphylococcal 29.62 9.97 55 285240 6036 110297968
Alveolar lung disease 29.41 9.97 20 285275 699 110303305
Atrial enlargement 29.12 9.97 24 285271 1127 110302877
Weight decreased 29.01 9.97 1481 283814 466576 109837428
Blood pressure systolic abnormal 28.81 9.97 14 285281 24836 110279168
Condition aggravated 28.80 9.97 1576 283719 733260 109570744
Blood pressure decreased 28.46 9.97 436 284859 114655 110189349
Pulmonary interstitial emphysema syndrome 28.41 9.97 18 285277 557 110303447
Ear infection 28.40 9.97 76 285219 62656 110241348
Cerebral haematoma 28.39 9.97 71 285224 9561 110294443
Pericardial effusion 28.31 9.97 248 285047 56969 110247035
Diaphragmatic spasm 28.23 9.97 11 285284 113 110303891
Wrong technique in product usage process 27.89 9.97 123 285172 87225 110216779
Blood pressure diastolic abnormal 27.78 9.97 16 285279 25799 110278205
Subileus 27.48 9.97 55 285240 6382 110297622
Abdominal pain upper 27.43 9.97 688 284607 348423 109955581
Injection site bruising 27.28 9.97 57 285238 51206 110252798
Small intestinal obstruction 27.28 9.97 159 285136 32054 110271950
Blood potassium abnormal 27.24 9.97 42 285253 3963 110300041
Blood albumin decreased 27.10 9.97 142 285153 27510 110276494
Pseudomonal sepsis 27.00 9.97 67 285228 8979 110295025
Vascular encephalopathy 26.96 9.97 20 285275 804 110303200
Electrocardiogram U wave present 26.87 9.97 11 285284 130 110303874
Coronary artery disease 26.78 9.97 293 285002 71397 110232607
Congestive hepatopathy 26.48 9.97 48 285247 5172 110298832
Electrocardiogram T wave peaked 26.36 9.97 23 285272 1169 110302835
Headache 26.05 9.97 1942 283353 880435 109423569
Haemoptysis 25.91 9.97 290 285005 71064 110232940
Nasal mucosal disorder 25.91 9.97 28 285267 1855 110302149
Haematotoxicity 25.81 9.97 11 285284 21071 110282933
Ischaemic cardiomyopathy 25.69 9.97 61 285234 7950 110296054
Iron deficiency anaemia 25.58 9.97 154 285141 31405 110272599
Lower gastrointestinal haemorrhage 25.57 9.97 105 285190 18381 110285623
Wrong patient 25.53 9.97 25 285270 1474 110302530
Accidental exposure to product 25.46 9.97 57 285238 49951 110254053
Faecal volume decreased 25.34 9.97 15 285280 410 110303594
Myocardial infarction 25.32 9.97 662 284633 191421 110112583
Depressed mood 25.09 9.97 77 285218 60732 110243272
Impaired work ability 24.89 9.97 19 285276 26400 110277604
Ventricular extrasystoles 24.82 9.97 120 285175 22521 110281483
Exercise tolerance decreased 24.78 9.97 78 285217 11989 110292015
Blood pressure systolic increased 24.64 9.97 120 285175 82871 110221133
Blood chloride decreased 24.61 9.97 65 285230 9050 110294954
Hepatitis 24.60 9.97 134 285161 89920 110214084
Pseudomonal bacteraemia 24.51 9.97 42 285253 4329 110299675
Bacteraemia 24.33 9.97 190 285105 42200 110261804
Oesophageal spasm 24.31 9.97 38 285257 3628 110300376
Haematochezia 24.25 9.97 426 284869 115098 110188906
Catheterisation cardiac 24.19 9.97 51 285244 6140 110297864
Multiple allergies 24.03 9.97 78 285217 12185 110291819
Pain in jaw 23.87 9.97 219 285076 50958 110253046
Multiple-drug resistance 23.85 9.97 3 285292 13232 110290772
Joint dislocation 23.76 9.97 32 285263 34158 110269846
Lymphocyte count decreased 23.76 9.97 239 285056 57004 110247000
Skin pressure mark 23.58 9.97 9 285286 87 110303917
Mitral valve incompetence 23.52 9.97 157 285138 33172 110270832
Post procedural complication 23.50 9.97 133 285162 26525 110277479
Hypertension 23.43 9.97 1076 284219 509008 109794996
Arteriovenous malformation 23.39 9.97 27 285268 1924 110302080
Sedation complication 23.30 9.97 11 285284 19844 110284160
Electrocardiogram QT prolonged 23.30 9.97 403 284892 108557 110195447
Nodule 23.23 9.97 30 285265 32601 110271403
Blood creatine increased 23.23 9.97 74 285221 11447 110292557
Atrioventricular block first degree 23.10 9.97 85 285210 14140 110289864
Acute pulmonary oedema 23.08 9.97 96 285199 16900 110287104
End stage renal disease 22.96 9.97 113 285182 21360 110282644
Acute left ventricular failure 22.94 9.97 29 285266 2272 110301732
Alkalosis 22.93 9.97 18 285277 788 110303216
Alkalosis hypochloraemic 22.90 9.97 16 285279 585 110303419
Neck pain 22.89 9.97 205 285090 122925 110181079
Stoma closure 22.88 9.97 14 285281 407 110303597
Electrocardiogram T wave amplitude decreased 22.64 9.97 18 285277 803 110303201
Calcium deficiency 22.57 9.97 21 285274 1161 110302843
Dystonia 22.52 9.97 20 285275 25785 110278219
International normalised ratio decreased 22.51 9.97 59 285236 8177 110295827
Urine chloride decreased 22.48 9.97 9 285286 100 110303904
Leukocytosis 22.46 9.97 225 285070 53603 110250401
Motor neurone disease 22.41 9.97 17 285278 707 110303297
Nausea 22.19 9.97 3569 281726 1232121 109071883
Coagulopathy 22.18 9.97 181 285114 40730 110263274
Pulmonary arterial pressure increased 22.12 9.97 44 285251 5083 110298921
Acute motor-sensory axonal neuropathy 22.09 9.97 15 285280 523 110303481
Blood phosphorus decreased 22.07 9.97 56 285239 7609 110296395
Hypochloraemia 21.93 9.97 36 285259 3582 110300422
Cardiomyopathy 21.93 9.97 155 285140 33370 110270634
Coma 21.73 9.97 426 284869 117443 110186561
Orthostatic hypotension 21.72 9.97 264 285031 65985 110238019
Supraventricular tachycardia 21.63 9.97 122 285173 24300 110279704
Peritonitis bacterial 21.55 9.97 68 285227 10465 110293539
Arrhythmia supraventricular 21.54 9.97 29 285266 2417 110301587
Ear pain 21.53 9.97 68 285227 53158 110250846
Agranulocytosis 21.52 9.97 249 285046 61511 110242493
Pulse absent 21.39 9.97 71 285224 11221 110292783
Transplant evaluation 21.34 9.97 25 285270 1810 110302194
Blood parathyroid hormone decreased 21.24 9.97 4 285291 13085 110290919
N-terminal prohormone brain natriuretic peptide increased 21.16 9.97 48 285247 6073 110297931
Post transplant lymphoproliferative disorder 21.03 9.97 7 285288 15606 110288398
Oesophageal pain 20.94 9.97 43 285252 5082 110298922
Increased bronchial secretion 20.92 9.97 37 285258 3911 110300093
Nail bed inflammation 20.90 9.97 26 285269 2004 110302000
Upper gastrointestinal haemorrhage 20.71 9.97 209 285086 49887 110254117
Pneumococcal sepsis 20.67 9.97 27 285268 2185 110301819
Neuropathy peripheral 20.57 9.97 607 284688 178670 110125334
Transient ischaemic attack 20.56 9.97 254 285041 63728 110240276
Hypophagia 20.55 9.97 217 285078 52409 110251595
Glomerular filtration rate 20.40 9.97 10 285285 185 110303819
Aggression 20.38 9.97 81 285214 59129 110244875
Memory impairment 20.14 9.97 372 284923 196572 110107432
Torsade de pointes 20.08 9.97 113 285182 22487 110281517
Nightmare 20.03 9.97 44 285251 38819 110265185
Nail dystrophy 20.02 9.97 20 285275 1208 110302796
Feeling hot 20.01 9.97 145 285150 90961 110213043
Clostridium difficile infection 19.91 9.97 214 285081 51915 110252089
Puncture site haematoma 19.90 9.97 11 285284 263 110303741
Renal tubular acidosis 19.78 9.97 40 285255 4675 110299329
Orthopnoea 19.73 9.97 68 285227 10953 110293051
Urine sodium decreased 19.71 9.97 11 285284 268 110303736
Right atrial pressure increased 19.64 9.97 12 285283 348 110303656
Oropharyngeal pain 19.53 9.97 239 285056 135037 110168967
Somnolence 19.40 9.97 946 284349 296503 110007501
Product administration error 19.29 9.97 163 285132 37054 110266950
Food allergy 19.24 9.97 14 285281 19934 110284070
Haemorrhage 19.13 9.97 384 284911 106308 110197696
Weight increased 19.11 9.97 886 284409 418758 109885246
Occult blood positive 19 9.97 52 285243 7393 110296611
Scleroderma 18.96 9.97 47 285248 6294 110297710
Movement disorder 18.94 9.97 41 285254 36363 110267641
Neuroleptic malignant syndrome 18.87 9.97 37 285258 34022 110269982
Ejection fraction decreased 18.59 9.97 174 285121 40706 110263298
Anhedonia 18.55 9.97 84 285211 15344 110288660
Blood immunoglobulin M increased 18.53 9.97 22 285273 1615 110302389
Cardio-respiratory arrest 18.53 9.97 410 284885 115426 110188578
Cytomegalovirus infection 18.41 9.97 75 285220 54369 110249635
Blood sodium decreased 18.39 9.97 165 285130 38154 110265850
Drug use disorder 18.34 9.97 12 285283 18062 110285942
Extrasystoles 18.23 9.97 55 285240 8263 110295741
Haemorrhoidal haemorrhage 18.20 9.97 54 285241 8039 110295965
Cardioversion 18.15 9.97 26 285269 2297 110301707
Decubitus ulcer 18.12 9.97 94 285201 18142 110285862
Haematuria 18.11 9.97 308 284987 82697 110221307
Acne 18.07 9.97 37 285258 33483 110270521
C-reactive protein increased 18.05 9.97 426 284869 217493 110086511
Hepatocellular injury 18.01 9.97 205 285090 50437 110253567
Lactic acidosis 17.98 9.97 338 284957 92473 110211531
Cholelithiasis 17.95 9.97 246 285049 63176 110240828
Euglycaemic diabetic ketoacidosis 17.93 9.97 4 285291 11619 110292385
Eosinophilic granulomatosis with polyangiitis 17.91 9.97 3 285292 10683 110293321
Lung perforation 17.77 9.97 8 285287 121 110303883
Emphysema 17.70 9.97 99 285196 19657 110284347
Hernia 17.66 9.97 98 285197 19402 110284602
Prothrombin consumption time prolonged 17.66 9.97 6 285289 40 110303964
Chills 17.65 9.97 629 284666 189951 110114053
Abortion spontaneous 17.51 9.97 39 285256 34243 110269761
Atrioventricular block 17.47 9.97 88 285207 16789 110287215
No adverse event 17.46 9.97 115 285180 73724 110230280
Catheter placement 17.44 9.97 31 285264 3289 110300715
Peritoneal haematoma 17.41 9.97 10 285285 258 110303746
Blood pressure diastolic decreased 17.39 9.97 42 285253 35843 110268161
Sleep apnoea syndrome 17.33 9.97 170 285125 40277 110263727
Psychotic disorder 17.33 9.97 70 285225 50867 110253137
Body temperature decreased 17.29 9.97 44 285251 36891 110267113
Haemorrhagic stroke 17.27 9.97 76 285219 13713 110290291
Pickwickian syndrome 17.26 9.97 13 285282 535 110303469
Petechiae 17.16 9.97 111 285184 23206 110280798
Mania 17.11 9.97 17 285278 20779 110283225
Transplant rejection 17.07 9.97 23 285272 24544 110279460
Catheter site haemorrhage 16.97 9.97 43 285252 5837 110298167
Hepatic encephalopathy 16.97 9.97 128 285167 28128 110275876
Purging 16.94 9.97 6 285289 46 110303958
Anxiety 16.84 9.97 723 284572 344355 109959649
Thrombotic microangiopathy 16.73 9.97 31 285264 29118 110274886
Polyneuropathy 16.70 9.97 36 285259 31976 110272028
Poisoning 16.66 9.97 31 285264 29074 110274930
Hemianopia 16.66 9.97 28 285267 2840 110301164
Neutropenia 16.66 9.97 1151 284144 373469 109930535
Polyuria 16.64 9.97 90 285205 17648 110286356
Alanine aminotransferase increased 16.64 9.97 605 284690 183168 110120836
Hepatic cytolysis 16.60 9.97 216 285079 54837 110249167
Tendonitis 16.57 9.97 26 285269 26057 110277947
Hypertransaminasaemia 16.56 9.97 23 285272 24232 110279772
Renal atrophy 16.51 9.97 25 285270 2321 110301683
Gastritis erosive 16.47 9.97 68 285227 11932 110292072
Scrotal oedema 16.46 9.97 21 285274 1660 110302344
Delirium 16.44 9.97 247 285048 134778 110169226
Drug effective for unapproved indication 16.40 9.97 8 285287 14159 110289845
Cardiovascular insufficiency 16.38 9.97 30 285265 3258 110300746
Completed suicide 16.35 9.97 488 284807 241893 110062111
Chest pain 16.32 9.97 1154 284141 375221 109928783
Extrapyramidal disorder 16.31 9.97 31 285264 28836 110275168
Femoral artery aneurysm 16.25 9.97 9 285286 216 110303788
Urosepsis 16.25 9.97 135 285160 30540 110273464
Resuscitation 16.21 9.97 28 285267 2905 110301099
Polyarthritis 16.19 9.97 15 285280 18948 110285056
Paracentesis 16.16 9.97 19 285276 1381 110302623
Renal phospholipidosis 16.11 9.97 11 285284 387 110303617
Anaphylactic reaction 16.10 9.97 203 285092 114097 110189907
Hepatic failure 16.08 9.97 258 285037 68481 110235523
Cardiac pacemaker insertion 16.07 9.97 44 285251 6257 110297747
Flail chest 16.04 9.97 7 285288 98 110303906
Oxygen saturation decreased 16.02 9.97 524 284771 156458 110147546
Osmotic demyelination syndrome 15.99 9.97 23 285272 2040 110301964
Bronchiectasis 15.93 9.97 45 285250 36448 110267556
Aspiration pleural cavity 15.92 9.97 21 285274 1716 110302288
Gastritis 15.90 9.97 210 285085 53489 110250515
Blood calcium increased 15.90 9.97 90 285205 17950 110286054
Injection site pruritus 15.87 9.97 73 285222 51185 110252819
Tachycardia 15.66 9.97 725 284570 225920 110078084
Affect lability 15.61 9.97 15 285280 18622 110285382
Streptococcal sepsis 15.60 9.97 38 285257 5034 110298970
Drug tolerance 15.53 9.97 12 285283 16573 110287431
Hiatus hernia 15.44 9.97 123 285172 27483 110276521
Cardiac operation 15.43 9.97 42 285253 5953 110298051
Pulmonary arterial wedge pressure increased 15.37 9.97 13 285282 633 110303371
Varicose vein 15.31 9.97 46 285249 6894 110297110
Sopor 15.27 9.97 46 285249 36500 110267504
Syringe issue 15.26 9.97 3 285292 9522 110294482
Presyncope 15.24 9.97 193 285102 48694 110255310
Pneumothorax spontaneous 15.18 9.97 21 285274 1796 110302208
Disease complication 15.17 9.97 41 285254 5786 110298218
Enterococcus test positive 15.11 9.97 27 285268 2877 110301127
Bacteroides infection 15.01 9.97 27 285268 2892 110301112
Ankylosing spondylitis 15.00 9.97 11 285284 15601 110288403
Cor pulmonale chronic 14.92 9.97 11 285284 438 110303566
Right ventricular dilatation 14.81 9.97 24 285271 2363 110301641
Neurologic neglect syndrome 14.75 9.97 3 285292 9295 110294709
Endometrial disorder 14.60 9.97 13 285282 679 110303325
Hyperthyroidism 14.56 9.97 127 285168 29134 110274870
Paranoia 14.50 9.97 22 285273 22352 110281652
Cardiac output decreased 14.50 9.97 22 285273 2047 110301957
Confusion postoperative 14.50 9.97 10 285285 358 110303646
Throat irritation 14.45 9.97 80 285215 53472 110250532
Disease progression 14.45 9.97 769 284526 243265 110060739
Middle insomnia 14.44 9.97 19 285276 20483 110283521
Fluid replacement 14.33 9.97 15 285280 958 110303046
Cardiac amyloidosis 14.28 9.97 26 285269 2811 110301193
Angioedema 14.23 9.97 174 285121 98326 110205678
Adenocarcinoma 14.17 9.97 33 285262 4247 110299757
Red blood cell count decreased 14.16 9.97 244 285051 65679 110238325
Ageusia 14.14 9.97 93 285202 19552 110284452
Mental status changes postoperative 14.12 9.97 8 285287 201 110303803
Blood fibrinogen decreased 14.08 9.97 25 285270 2650 110301354
Shoshin beriberi 14.07 9.97 6 285289 79 110303925
Glomerular filtration rate decreased 14.06 9.97 125 285170 28831 110275173
Cardioactive drug level decreased 14.05 9.97 8 285287 203 110303801
Troponin T increased 14.04 9.97 33 285262 4273 110299731
Enterobacter pneumonia 14.04 9.97 12 285283 593 110303411
Cardiac pacemaker evaluation 14.02 9.97 7 285288 135 110303869
Electrocardiogram ST segment abnormal 13.98 9.97 20 285275 1765 110302239
Oesophagitis 13.96 9.97 124 285171 28591 110275413
Cytomegalovirus infection reactivation 13.96 9.97 16 285279 18317 110285687
Unintentional medical device removal 13.91 9.97 3 285292 8920 110295084
Peri-implantitis 13.91 9.97 8 285287 207 110303797
Skin candida 13.89 9.97 23 285272 2305 110301699
Haemorrhoids 13.88 9.97 147 285148 35525 110268479
Fear of injection 13.88 9.97 3 285292 8908 110295096
Blood immunoglobulin G abnormal 13.88 9.97 7 285288 138 110303866
Pustular psoriasis 13.85 9.97 9 285286 13596 110290408
Exposure to toxic agent 13.79 9.97 8 285287 12850 110291154
Systemic infection 13.76 9.97 56 285239 9763 110294241
Complication of device insertion 13.72 9.97 3 285292 8835 110295169
Product substitution issue 13.71 9.97 24 285271 23037 110280967
Coagulation factor VII level decreased 13.70 9.97 8 285287 213 110303791
Asphyxia 13.68 9.97 10 285285 14205 110289799
Type IIa hyperlipidaemia 13.64 9.97 11 285284 501 110303503
Urinary retention 13.58 9.97 254 285041 69429 110234575
Wrong patient received product 13.58 9.97 43 285252 6631 110297373
Breath sounds abnormal 13.56 9.97 112 285183 25292 110278712
Arteriosclerosis coronary artery 13.55 9.97 111 285184 25007 110278997
Benign prostatic hyperplasia 13.54 9.97 87 285208 18147 110285857
Circulatory collapse 13.52 9.97 170 285125 42823 110261181
Blood immunoglobulin M abnormal 13.48 9.97 7 285288 147 110303857
Neonatal gastrointestinal disorder 13.42 9.97 5 285290 45 110303959
Pantoea agglomerans infection 13.40 9.97 7 285288 149 110303855
Dermatitis exfoliative generalised 13.39 9.97 60 285235 10912 110293092
Gastrointestinal sounds abnormal 13.38 9.97 40 285255 5978 110298026
Rheumatic disorder 13.36 9.97 29 285266 3562 110300442
Congenital hiatus hernia 13.35 9.97 41 285254 6218 110297786
Tracheal obstruction 13.34 9.97 8 285287 224 110303780
Foetal death 13.34 9.97 13 285282 16032 110287972
Lung consolidation 13.32 9.97 58 285237 10418 110293586
Heparin-induced thrombocytopenia test 13.31 9.97 8 285287 225 110303779
Neuralgia 13.30 9.97 187 285108 48291 110255713
Pre-eclampsia 13.30 9.97 3 285292 8647 110295357
Respiratory tract infection bacterial 13.26 9.97 23 285272 2393 110301611
N-terminal prohormone brain natriuretic peptide abnormal 13.25 9.97 9 285286 314 110303690
Lymphadenectomy 13.21 9.97 18 285277 1518 110302486
Micturition disorder 13.19 9.97 34 285261 4664 110299340
Wrong strength 13.18 9.97 8 285287 229 110303775
Rales 13.17 9.97 109 285186 24630 110279374
Right ventricular systolic pressure increased 13.16 9.97 15 285280 1054 110302950
Tricuspid valve incompetence 13.15 9.97 106 285189 23767 110280237
Blood immunoglobulin A decreased 13.13 9.97 22 285273 2226 110301778
Mitral valve disease 13.13 9.97 28 285267 3397 110300607
Nasal polyps 13.08 9.97 9 285286 13191 110290813
Foetal heart rate disorder 13.04 9.97 5 285290 49 110303955
Limited symptom panic attack 13.04 9.97 5 285290 49 110303955
Lower respiratory tract infection bacterial 12.98 9.97 15 285280 1070 110302934
Catheter culture positive 12.91 9.97 8 285287 238 110303766
Peripheral vascular disorder 12.89 9.97 50 285245 8526 110295478
Skin reaction 12.82 9.97 96 285199 21048 110282956
Anterior chamber disorder 12.79 9.97 7 285288 164 110303840
Cyanosis 12.74 9.97 125 285170 29616 110274388
Diverticulum 12.74 9.97 76 285219 15450 110288554
Sinus bradycardia 12.67 9.97 124 285171 29359 110274645
Blood glucose decreased 12.66 9.97 124 285171 29364 110274640
Adjustment disorder 12.64 9.97 6 285289 10789 110293215
Hydronephrosis 12.63 9.97 94 285201 20571 110283433
Deposit eye 12.61 9.97 5 285290 54 110303950
Enterococcal sepsis 12.61 9.97 27 285268 3285 110300719
Oesophageal carcinoma 12.61 9.97 7 285288 11517 110292487
Acute myocardial infarction 12.61 9.97 294 285001 83483 110220521
Neurological symptom 12.57 9.97 13 285282 15595 110288409
Haemorrhage intracranial 12.53 9.97 122 285173 28847 110275157
Panniculitis 12.52 9.97 13 285282 15569 110288435
Injection site rash 12.50 9.97 26 285269 23393 110280611
Mood swings 12.45 9.97 25 285270 22787 110281217
Blood albumin abnormal 12.45 9.97 13 285282 828 110303176
Transient aphasia 12.40 9.97 12 285283 697 110303307
Familial periodic paralysis 12.39 9.97 9 285286 350 110303654
Vasculitis 12.39 9.97 49 285246 35824 110268180
Ischaemic cerebral infarction 12.38 9.97 25 285270 2920 110301084
Dissociation 12.27 9.97 5 285290 9837 110294167
Dysuria 12.24 9.97 221 285074 60010 110243994
Stasis dermatitis 12.24 9.97 19 285276 1803 110302201
Hyperbilirubinaemia 12.22 9.97 127 285168 30544 110273460
Skin dystrophy 12.22 9.97 5 285290 59 110303945
Lymphoid tissue hypoplasia 12.09 9.97 18 285277 1647 110302357
Cataract operation 12.06 9.97 38 285257 5845 110298159
Throat tightness 12.05 9.97 45 285250 33444 110270560
Rash vesicular 12.03 9.97 12 285283 14640 110289364
Thyroid disorder 12.01 9.97 80 285215 16889 110287115
Thoracic operation 11.99 9.97 8 285287 271 110303733
Total lung capacity decreased 11.97 9.97 43 285252 7071 110296933
Pneumonia klebsiella 11.94 9.97 41 285254 6591 110297413
Renal injury 11.94 9.97 86 285209 18627 110285377
Thymus hypoplasia 11.91 9.97 18 285277 1669 110302335
Haematoma muscle 11.90 9.97 30 285265 4060 110299944
Lip erosion 11.90 9.97 19 285276 1847 110302157
Diverticulum intestinal haemorrhagic 11.89 9.97 33 285262 4730 110299274
Acute hepatic failure 11.86 9.97 51 285244 36417 110267587
Device related sepsis 11.84 9.97 45 285250 7602 110296402
Hyperuricaemia 11.84 9.97 71 285224 14460 110289544
Hypoproteinaemia 11.82 9.97 38 285257 5907 110298097
Carbon dioxide increased 11.78 9.97 24 285271 2820 110301184
Product prescribing error 11.76 9.97 192 285103 51139 110252865
COVID-19 pneumonia 11.74 9.97 147 285148 36996 110267008
Spinal cord paralysis 11.71 9.97 7 285288 195 110303809
Substance abuse 11.69 9.97 9 285286 12454 110291550
Sputum increased 11.65 9.97 37 285258 5714 110298290
Neutrophil count decreased 11.65 9.97 401 284894 120540 110183464
Stress 11.62 9.97 355 284940 104993 110199011
Epstein-Barr virus infection 11.60 9.97 19 285276 18719 110285285
Altered visual depth perception 11.56 9.97 10 285285 502 110303502
Renin decreased 11.51 9.97 6 285289 127 110303877
Tonsillar haemorrhage 11.51 9.97 8 285287 290 110303714
Catheter site erythema 11.50 9.97 38 285257 5990 110298014
Diuretic therapy 11.49 9.97 7 285288 202 110303802
Electrocardiogram P wave abnormal 11.49 9.97 9 285286 393 110303611
Toxic skin eruption 11.47 9.97 115 285180 27400 110276604
Initial insomnia 11.34 9.97 55 285240 10334 110293670
Catheter removal 11.34 9.97 11 285284 641 110303363
Rash maculo-papular 11.33 9.97 261 285034 73961 110230043
Hypertrophy 11.31 9.97 13 285282 922 110303082
Neuromyopathy 11.19 9.97 18 285277 1761 110302243
International normalised ratio abnormal 11.19 9.97 39 285256 6318 110297686
Pancreatitis acute 11.16 9.97 218 285077 60056 110243948
Blood immunoglobulin G increased 11.15 9.97 28 285267 3780 110300224
Injection site urticaria 11.09 9.97 17 285278 17198 110286806
Diastolic dysfunction 11.01 9.97 62 285233 12342 110291662
Bronchial disorder 11.00 9.97 23 285272 2753 110301251
Heart transplant 10.97 9.97 17 285278 1611 110302393
Blood aldosterone increased 10.95 9.97 7 285288 220 110303784
Drug chemical incompatibility 10.95 9.97 6 285289 141 110303863
Glomerular filtration rate abnormal 10.95 9.97 21 285274 2362 110301642
Depressed level of consciousness 10.88 9.97 214 285081 112064 110191940
Spondylitis 10.88 9.97 8 285287 11330 110292674
Mastoid effusion 10.83 9.97 4 285291 35 110303969
Suspected suicide 10.79 9.97 14 285281 15185 110288819
Dyskinesia 10.76 9.97 83 285212 51363 110252641
Drug reaction with eosinophilia and systemic symptoms 10.76 9.97 148 285147 81947 110222057
Abortion incomplete complicated 10.75 9.97 3 285292 9 110303995
Vascular access malfunction 10.70 9.97 7 285288 229 110303775
Aortic valve disease 10.69 9.97 20 285275 2207 110301797
Renal tubular necrosis 10.67 9.97 123 285172 30352 110273652
Overlap syndrome 10.66 9.97 5 285290 9054 110294950
Lactobacillus test positive 10.64 9.97 4 285291 37 110303967
Forced expiratory volume decreased 10.58 9.97 11 285284 13165 110290839
Skin disorder 10.57 9.97 66 285229 42847 110261157
Oral papilloma 10.53 9.97 5 285290 86 110303918
Gestational diabetes 10.52 9.97 3 285292 7386 110296618
Sensory loss 10.48 9.97 25 285270 21432 110282572
Neonatal respiratory depression 10.48 9.97 5 285290 87 110303917
Adenocarcinoma pancreas 10.47 9.97 20 285275 2243 110301761
BK virus infection 10.46 9.97 11 285284 13095 110290909
Injection site warmth 10.45 9.97 18 285277 17387 110286617
HLA-B*27 positive 10.44 9.97 6 285289 155 110303849
Epidermolysis 10.43 9.97 14 285281 1164 110302840
Death of relative 10.42 9.97 8 285287 339 110303665
Electrocardiogram U-wave abnormality 10.37 9.97 5 285290 89 110303915
Cystitis 10.33 9.97 233 285062 65803 110238201
Peptic ulcer 10.32 9.97 43 285252 7576 110296428
Hyperdynamic left ventricle 10.32 9.97 10 285285 582 110303422
Urine output decreased 10.27 9.97 87 285208 19789 110284215
Visual impairment 10.25 9.97 266 285029 134162 110169842
Injection site haemorrhage 10.25 9.97 47 285248 32981 110271023
Stevens-Johnson syndrome 10.22 9.97 174 285121 46727 110257277
Hip fracture 10.22 9.97 137 285158 35014 110268990
Diabetes mellitus 10.20 9.97 332 284963 99049 110204955
Catheter site pruritus 10.20 9.97 20 285275 2286 110301718
Euphoric mood 10.19 9.97 5 285290 8822 110295182
Spontaneous haemorrhage 10.15 9.97 14 285281 1194 110302810
Photosensitivity reaction 10.14 9.97 33 285262 25556 110278448
Abortion induced 10.12 9.97 4 285291 8015 110295989
Catheter site scab 10.11 9.97 7 285288 252 110303752
Blood aldosterone abnormal 10.11 9.97 4 285291 43 110303961
Cerebral haemorrhage 10.09 9.97 229 285066 64739 110239265
Iatrogenic infection 10.08 9.97 5 285290 95 110303909
Cortical visual impairment 10.02 9.97 4 285291 44 110303960
Pupillary block 10.02 9.97 4 285291 44 110303960
Haematemesis 10.02 9.97 211 285084 58897 110245107
Influenza like illness 10.00 9.97 164 285131 88248 110215756
Varices oesophageal 9.99 9.97 41 285254 7174 110296830
Bundle branch block right 9.98 9.97 60 285235 12231 110291773

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A12BA01 ALIMENTARY TRACT AND METABOLISM
MINERAL SUPPLEMENTS
POTASSIUM
Potassium
ATC B05XA01 BLOOD AND BLOOD FORMING ORGANS
BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
I.V. SOLUTION ADDITIVES
Electrolyte solutions
CHEBI has role CHEBI:33287 fertilizer
CHEBI has role CHEBI:35554 cardiovascular drug
CHEBI has role CHEBI:35610 antineoplastic agent
CHEBI has role CHEBI:35674 antihypertensive agent
CHEBI has role CHEBI:38070 anti-arrhythmia drug
CHEBI has role CHEBI:50503 laxative
CHEBI has role CHEBI:228364 NMR chemical shift reference compound

Related Drugs by ATC class:

A12BA Potassium 4 drugs
potassium bitartratepotassium citratepotassium gluconatepotassium hydrogencarbonate
B05XA Electrolyte solutions 18 drugs
ammonium chloridecalcium chloridecalcium gluconatehydrochloric acidmagnesium chloridemagnesium phosphatemagnesium sulfatepotassium acetatepotassium lactatepotassium phosphatesodium acetatesodium bicarbonate show all 18 →

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Constipation indication 14760008 DOID:2089
Hypokalemia indication 43339004
Incomplete passage of stool indication 249515001
Hypokalemia Prevention indication
Brain damage contraindication 2470005
Anuria contraindication 2472002 DOID:2983
Hypocalcemia contraindication 5291005
Tachyarrhythmia contraindication 6285003
Urinary tract obstruction contraindication 7163005 DOID:5200
Poisoning by digitalis glycoside contraindication 12876009
Peptic ulcer contraindication 13200003 DOID:750
Chronic obstructive lung disease contraindication 13645005 DOID:3083
Hyperkalemia contraindication 14140009
Severe chronic ulcerative colitis contraindication 14311001
Primary hyperoxaluria contraindication 17901006 DOID:2977
Myocardial infarction contraindication 22298006 DOID:5844
Acute vomiting contraindication 23971007
Ventricular tachycardia contraindication 25569003
Complete atrioventricular block contraindication 27885002
Toxic megacolon contraindication 28536002 DOID:1770
Atony of colon contraindication 29479008
Acute epiglottitis contraindication 29608009 DOID:9398
Sarcoidosis contraindication 31541009 DOID:11335
Hyperthyroidism contraindication 34486009 DOID:7998
Acute hepatitis contraindication 37871000
Hypertensive disorder contraindication 38341003 DOID:10763
Gastrointestinal ulcer contraindication 40845000
Complete trisomy 21 syndrome contraindication 41040004 DOID:14250
Toxic colitis contraindication 42359007
Achalasia of esophagus contraindication 45564002 DOID:9164
End stage renal disease contraindication 46177005 DOID:784
Humoral hypercalcemia of malignancy contraindication 47709007
Chronic heart failure contraindication 48447003
Bradycardia contraindication 48867003
Acidosis contraindication 51387008
Gastrointestinal perforation contraindication 51875005
Paralytic ileus contraindication 55525008 DOID:8442
Heart disease contraindication 56265001 DOID:114
Perforation of intestine contraindication 56905009 DOID:2074
Peptic reflux disease contraindication 57643001
Congenital myotonia, autosomal dominant form contraindication 57938005
Acute nephropathy contraindication 58574008
Metabolic acidosis contraindication 59455009
Ulcerative colitis contraindication 64766004 DOID:8577
Arterial thrombosis contraindication 65198009
Drug AND/OR toxin-induced diarrhea contraindication 65979008
Hypercalcemia contraindication 66931009 DOID:12678
Ventricular fibrillation contraindication 71908006
Hypercalciuria contraindication 71938000
Incontinence of feces contraindication 72042002
Arteriosclerotic vascular disease contraindication 72092001
Appendicitis contraindication 74400008 DOID:8337
Hyperchloremia contraindication 74450001
Spastic paralysis contraindication 78403003
Disturbance of salivary secretion contraindication 78948009
Third degree burn injury contraindication 80247002
Intestinal obstruction contraindication 81060008 DOID:8437
Chronic idiopathic constipation contraindication 82934008
Oliguria contraindication 83128009
Hiatal hernia contraindication 84089009 DOID:12642
Hyponatremia contraindication 89627008
Kidney disease contraindication 90708001 DOID:557
Myasthenia gravis contraindication 91637004 DOID:437
Kidney stone contraindication 95570007
Anemia due to enzyme deficiency contraindication 111577008
Gastrointestinal obstruction contraindication 126765001
Hb SS disease contraindication 127040003 DOID:10923
Seizure disorder contraindication 128613002
Autonomic dysreflexia contraindication 129618003
Bleeding contraindication 131148009
Partial atrioventricular block contraindication 195039008
Acute pancreatitis contraindication 197456007 DOID:2913
Myocardial dysfunction contraindication 233928007
Gastroparesis contraindication 235675006
Disease of liver contraindication 235856003 DOID:409
Hyporeninemic hypoaldosteronism contraindication 236464008
Bladder outflow obstruction contraindication 236645006
Pyloric obstruction contraindication 244815007
Esophageal dysmotility contraindication 266434009 DOID:9192
Benign prostatic hyperplasia contraindication 266569009
Edema contraindication 267038008
Retention of urine contraindication 267064002
Drowsy contraindication 271782001
Familial hyperkalemic periodic paralysis contraindication 304737009 DOID:14451
Gastric retention contraindication 307227006
At risk for aspiration contraindication 371736008
Primary adrenocortical insufficiency contraindication 373662000
Hypoxia contraindication 389086002
Angle-closure glaucoma contraindication 392291006 DOID:13550
Gastric ulcer contraindication 397825006 DOID:10808
Hemochromatosis contraindication 399187006 DOID:2352
Chronic lung disease contraindication 413839001
Disorder of coronary artery contraindication 414024009
Unconscious contraindication 418107008
Hypertensive urgency contraindication 443482000
Azotemia contraindication 445009001
Severe dehydration contraindication 450316000
Esophageal Compression contraindication
Predisposition to Nausea and Vomiting contraindication
Suppression of the Gag Reflex contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRoutePatent numberPatent expiration datePatent use
7.54GM;140GM;2.2GM;48.11GM;5.2GM;9GM PLENVU SALIX N209381 May 4, 2018 RX FOR SOLUTION ORAL 10792306 March 9, 2032 FOR CLEANSING OF THE COLON IN PREPARATION FOR COLONOSCOPY IN ADULTS
7.54GM;140GM;2.2GM;48.11GM;5.2GM;9GM PLENVU SALIX N209381 May 4, 2018 RX FOR SOLUTION ORAL 11529368 March 9, 2032 FOR CLEANSING OF THE COLON IN PREPARATION FOR COLONOSCOPY IN ADULTS
7.54GM;140GM;2.2GM;48.11GM;5.2GM;9GM PLENVU SALIX N209381 May 4, 2018 RX FOR SOLUTION ORAL 9592252 Aug. 11, 2032 FOR CLEANSING OF THE COLON IN PREPARATION FOR COLONOSCOPY IN ADULTS
7.54GM;140GM;2.2GM;48.11GM;5.2GM;9GM PLENVU SALIX N209381 May 4, 2018 RX FOR SOLUTION ORAL 10918723 Sept. 10, 2033 FOR CLEANSING OF THE COLON IN PREPARATION FOR COLONOSCOPY IN ADULTS
7.54GM;140GM;2.2GM;48.11GM;5.2GM;9GM PLENVU SALIX N209381 May 4, 2018 RX FOR SOLUTION ORAL 12083179 Sept. 10, 2033 FOR CLEANSING OF THE COLON IN PREPARATION FOR COLONOSCOPY IN ADULTS
7.54GM;140GM;2.2GM;48.11GM;5.2GM;9GM PLENVU SALIX N209381 May 4, 2018 RX FOR SOLUTION ORAL 9326969 Sept. 10, 2033 FOR CLEANSING OF THE COLON IN PREPARATION FOR COLONOSCOPY IN ADULTS
0.225GM;0.188GM;1.479GM SUTAB AZURITY N213135 Nov. 10, 2020 RX TABLET ORAL 11033498 Aug. 4, 2037 GASTROINTESTINAL TABLETS INDICATED FOR CLEANSING THE COLON IN PREPARATION FOR COLONOSCOPY
0.225GM;0.188GM;1.479GM SUTAB AZURITY N213135 Nov. 10, 2020 RX TABLET ORAL 11382864 Aug. 4, 2037 GASTROINTESTINAL TABLETS INDICATED FOR CLEANSING THE COLON IN PREPARATION FOR COLONOSCOPY
0.9GM/BOT;178.7GM/BOT;1.12GM/BOT;0.5GM/BOT;7.3GM/BOT SUFLAVE AZURITY N215344 June 15, 2023 RX FOR SOLUTION ORAL 12239659 June 14, 2044 GASTROINTESTINAL FLAVORED SOLUTION INDICATED FOR CLEANSING THE COLON IN PREPARATION FOR COLONOSCOPY
0.9GM/BOT;178.7GM/BOT;1.12GM/BOT;0.5GM/BOT;7.3GM/BOT SUFLAVE AZURITY N215344 June 15, 2023 RX FOR SOLUTION ORAL 12433914 June 14, 2044 GASTROINTESTINAL FLAVORED SOLUTION INDICATED FOR CLEANSING THE COLON IN PREPARATION FOR COLONOSCOPY

Orange Book exclusivity data (new drug applications)

Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRouteExclusivity dateDescription
0.9GM/BOT;178.7GM/BOT;1.12GM/BOT;0.5GM/BOT;7.3GM/BOT SUFLAVE AZURITY N215344 June 15, 2023 RX FOR SOLUTION ORAL June 15, 2026 NEW PRODUCT

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Carbonic anhydrase 4 Enzyme Ki 4.05 CHEMBL

External reference:

IDSource
4020361 VUID
N0000148186 NUI
D02060 KEGG_DRUG
4017447 VANDF
4020073 VANDF
4020361 VANDF
C0032825 UMLSCUI
CHEBI:32588 CHEBI
CHEMBL1200731 ChEMBL_ID
D011189 MESH_DESCRIPTOR_UI
DB00761 DRUGBANK_ID
660YQ98I10 UNII
4873 PUBCHEM_CID
8591 RXNORM
5326 MMSL
7330 MMSL
d00345 MMSL
000767 NDDF
007231 NDDF
420155008 SNOMEDCT_US
8631001 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
BSS HUMAN PRESCRIPTION DRUG LABEL 6 0065-0795 SOLUTION 0.75 mg OPHTHALMIC NDA 9 sections
BSS HUMAN PRESCRIPTION DRUG LABEL 6 0065-0795 SOLUTION 0.75 mg OPHTHALMIC NDA 9 sections
BSS HUMAN PRESCRIPTION DRUG LABEL 6 0065-1795 SOLUTION 0.75 mg OPHTHALMIC NDA 9 sections
Potassium Chloride HUMAN PRESCRIPTION DRUG LABEL 1 0121-0948 SOLUTION 20 meq ORAL ANDA 21 sections
Potassium Chloride HUMAN PRESCRIPTION DRUG LABEL 1 0121-0948 SOLUTION 20 meq ORAL ANDA 21 sections
Potassium Chloride HUMAN PRESCRIPTION DRUG LABEL 1 0121-1896 SOLUTION 20 meq ORAL ANDA 21 sections
Potassium Chloride HUMAN PRESCRIPTION DRUG LABEL 1 0121-1896 SOLUTION 20 meq ORAL ANDA 21 sections
Potassium Chloride HUMAN PRESCRIPTION DRUG LABEL 1 0121-2847 SOLUTION 40 meq ORAL ANDA 21 sections
Potassium Chloride HUMAN PRESCRIPTION DRUG LABEL 1 0121-2847 SOLUTION 40 meq ORAL ANDA 21 sections
Potassium Chloride HUMAN PRESCRIPTION DRUG LABEL 1 0121-4948 SOLUTION 20 meq ORAL ANDA 21 sections
Potassium Chloride HUMAN PRESCRIPTION DRUG LABEL 1 0121-4948 SOLUTION 20 meq ORAL ANDA 21 sections
KLOR-CON HUMAN PRESCRIPTION DRUG LABEL 1 0245-0360 POWDER, FOR SOLUTION 1.50 g ORAL ANDA 21 sections
KLOR-CON HUMAN PRESCRIPTION DRUG LABEL 1 0245-0835 TABLET, FILM COATED, EXTENDED RELEASE 600 mg ORAL ANDA 25 sections
KLOR-CON HUMAN PRESCRIPTION DRUG LABEL 1 0245-0836 TABLET, FILM COATED, EXTENDED RELEASE 750 mg ORAL ANDA 25 sections
KLOR-CON HUMAN PRESCRIPTION DRUG LABEL 1 0245-5315 TABLET, FILM COATED, EXTENDED RELEASE 600 mg ORAL NDA 25 sections
KLOR-CON HUMAN PRESCRIPTION DRUG LABEL 1 0245-5316 TABLET, FILM COATED, EXTENDED RELEASE 750 mg ORAL NDA 25 sections
KLOR-CON M HUMAN PRESCRIPTION DRUG LABEL 1 0245-5317 TABLET, EXTENDED RELEASE 750 mg ORAL ANDA 21 sections
KLOR-CON M HUMAN PRESCRIPTION DRUG LABEL 1 0245-5318 TABLET, EXTENDED RELEASE 1125 mg ORAL ANDA 21 sections
KLOR-CON M HUMAN PRESCRIPTION DRUG LABEL 1 0245-5319 TABLET, EXTENDED RELEASE 1500 mg ORAL ANDA 21 sections
POTASSIUM CHLORIDE HUMAN PRESCRIPTION DRUG LABEL 1 0264-1944 INJECTION, SOLUTION, CONCENTRATE 14.90 g PARENTERAL ANDA 15 sections
POTASSIUM CHLORIDE HUMAN PRESCRIPTION DRUG LABEL 1 0264-1944 INJECTION, SOLUTION, CONCENTRATE 14.90 g PARENTERAL ANDA 15 sections
Balanced Salt HUMAN PRESCRIPTION DRUG LABEL 6 0264-1945 SOLUTION 0.75 mg IRRIGATION ANDA 11 sections
Ringers HUMAN PRESCRIPTION DRUG LABEL 3 0264-2202 IRRIGANT 0.03 g IRRIGATION NDA 22 sections
Ringers HUMAN PRESCRIPTION DRUG LABEL 3 0264-2202 IRRIGANT 0.03 g IRRIGATION NDA 22 sections
Lactated Ringers HUMAN PRESCRIPTION DRUG LABEL 4 0264-2203 IRRIGANT 0.03 g IRRIGATION NDA 18 sections
Lactated Ringers HUMAN PRESCRIPTION DRUG LABEL 4 0264-2203 IRRIGANT 0.03 g IRRIGATION NDA 18 sections
Physiolyte HUMAN PRESCRIPTION DRUG LABEL 5 0264-2205 IRRIGANT 0.04 g IRRIGATION NDA 20 sections
Physiolyte HUMAN PRESCRIPTION DRUG LABEL 5 0264-2205 IRRIGANT 0.04 g IRRIGATION NDA 20 sections
Lactated Ringers Irrigation HUMAN PRESCRIPTION DRUG LABEL 4 0264-7389 SOLUTION 30 mg IRRIGATION NDA 14 sections
Lactated Ringers Irrigation HUMAN PRESCRIPTION DRUG LABEL 4 0264-7389 SOLUTION 30 mg IRRIGATION NDA 14 sections