potassium gluconate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
4524 299-27-4

Description:

MoleculeDescription

Synonyms:

  • potassium gluconate
  • gluconic acid monopotassium salt
  • gluconic acid potassium salt
  • Molecular weight: 234.25
  • Formula: C6H11KO7
  • CLOGP: -7.82
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 141.28
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Blood creatine increased 132.55 21.49 31 2057 6936 90619423
Dehydration 66.03 21.49 46 2042 194401 90431958
Pyroglutamic acidosis 31.33 21.49 7 2081 1273 90625086
Diarrhoea 28.59 21.49 65 2023 939125 89687234
Blood potassium decreased 25.34 21.49 15 2073 47712 90578647
Urinary tract infection 23.64 21.49 32 2056 305600 90320759

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Toxic epidermal necrolysis 153.18 25.03 47 1050 26703 42593535
Pneumonia 27.50 25.03 43 1054 422106 42198132

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Toxic epidermal necrolysis 117.58 21.89 47 2825 56680 110529747
Blood creatine increased 113.32 21.89 31 2841 11490 110574937
Dehydration 58.00 21.89 52 2820 279459 110306968
Pneumonia 29.53 21.89 68 2804 876646 109709781
Pyroglutamic acidosis 27.15 21.89 7 2865 2061 110584366
Platelet count decreased 26.08 21.89 31 2841 230412 110356015
Diarrhoea 22.84 21.89 73 2799 1139432 109446995

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A12BA05 ALIMENTARY TRACT AND METABOLISM
MINERAL SUPPLEMENTS
POTASSIUM
Potassium

Related Drugs by ATC class:

A12BA Potassium 4 drugs
potassium bitartratepotassium chloridepotassium citratepotassium hydrogencarbonate

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Hypokalemia indication 43339004
Hypokalemia Prevention indication
Hyperkalemia contraindication 14140009
Complete atrioventricular block contraindication 27885002
Gastrointestinal ulcer contraindication 40845000
Congenital myotonia, autosomal dominant form contraindication 57938005
Acute nephropathy contraindication 58574008
Gastrointestinal obstruction contraindication 126765001
Gastroparesis contraindication 235675006
Chronic diarrhea contraindication 236071009
Hyporeninemic hypoaldosteronism contraindication 236464008
Familial hyperkalemic periodic paralysis contraindication 304737009 DOID:14451
Severe dehydration contraindication 450316000




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01298 KEGG_DRUG
4018112 VUID
N0000146450 NUI
4018112 VANDF
CHEBI:32032 CHEBI
CHEMBL2106978 ChEMBL_ID
DB13620 DRUGBANK_ID
12H3K5QKN9 UNII
89903 RXNORM
5331 MMSL
6390 MMSL
d03789 MMSL
000768 NDDF
424654004 SNOMEDCT_US
89219006 SNOMEDCT_US
C0301527 UMLSCUI
16760467 PUBCHEM_CID

Pharmaceutical products:

None