fluperolone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
steroids not used as glucocorticosteroids 3237 2119-75-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • methral
  • fluperolone
  • alacortril
  • fluperolone acetate
  • Molecular weight: 434.50
  • Formula: C24H31FO6
  • CLOGP: 2.33
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 2
  • TPSA: 100.90
  • ALOGS: -4.40
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC D07AB05 DERMATOLOGICALS
CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
CORTICOSTEROIDS, PLAIN
Corticosteroids, moderately potent (group II)
MeSH PA D005938 Glucocorticoids
MeSH PA D006728 Hormones

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 11.08 acidic
pKa2 13.01 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D04225 KEGG_DRUG
3841-11-0 SECONDARY_CAS_RN
CHEBI:135705 CHEBI
CHEMBL2107401 ChEMBL_ID
C005017 MESH_SUPPLEMENTAL_RECORD_UI
DB13491 DRUGBANK_ID
C3652595 UMLSCUI
1473 INN_ID
56841872 PUBCHEM_CID
S33056JLS5 UNII

Pharmaceutical products:

None