All FDA-approved EMA-approved PMDA-approved
Target Card Uniprot Example: P23975

pravastatin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
antihyperlipidaemic substances, HMG CoA reductase inhibitors	2239	81093-37-0

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: pravastatin eptastatin mevalothin pravastatin acid pravastatin sodium pravachol	An antilipemic fungal metabolite isolated from cultures of Nocardia autotrophica. It acts as a competitive inhibitor of HMG CoA reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES). Molecular weight: 424.53 Formula: C23H36O7 CLOGP: 2.05 LIPINSKI: 0 HAC: 7 HDO: 4 TPSA: 124.29 ALOGS: -3.24 ROTB: 11 Status: OFP Legend: OFP - off patent OFM - off market ONP - on patent

Drug dosage:

Dose	Unit	Route
30	mg	O

ADMET properties:

Property	Value	Reference
MRTD (Maximum Recommended Therapeutic Daily Dose)	1.57 µM/kg/day	Contrera JF, Matthews EJ, Kruhlak NL, Benz RD
BDDCS (Biopharmaceutical Drug Disposition Classification System)	3	Hosey CM, Chan R, Benet LZ
S (Water solubility)	300 mg/mL	Bocci G, Oprea TI, Benet LZ
EoM (Fraction excreted unchanged in urine)	47 %	Hosey CM, Chan R, Benet LZ
BA (Bioavailability)	18 %	Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H
Vd (Volume of distribution)	0.46 L/kg	Lombardo F, Berellini G, Obach RS
CL (Clearance)	14 mL/min/kg	Lombardo F, Berellini G, Obach RS
fu (Fraction unbound in plasma)	0.50 %	Lombardo F, Berellini G, Obach RS
t_half (Half-life)	0.78 hours	Lombardo F, Berellini G, Obach RS

Approvals:

Date	Agency	Company	Orphan
Oct. 31, 1991	FDA	BRISTOL MYERS SQUIBB

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Myalgia	223.61	10.68	417	51518	146112	63290975
Contraindicated product administered	136.68	10.68	11	51924	217637	63219450
Hand deformity	116.28	10.68	3	51932	159454	63277633
Acute kidney injury	113.43	10.68	471	51464	262944	63174143
Systemic lupus erythematosus	108.21	10.68	20	51915	208898	63228189
Synovitis	103.26	10.68	15	51920	186903	63250184
Glossodynia	97.32	10.68	15	51920	178861	63258226
Product dose omission issue	90.09	10.68	405	51530	233908	63203179
Drug ineffective	88.37	10.68	499	51436	1044266	62392821
Pericarditis	87.39	10.68	5	51930	131574	63305513
Maternal exposure during pregnancy	84.67	10.68	37	51898	220025	63217062
Treatment failure	82.25	10.68	30	51905	199013	63238074
Wound	79.61	10.68	18	51917	163245	63273842
Lower respiratory tract infection	72.17	10.68	11	51924	132296	63304791
Fall	67.72	10.68	550	51385	391784	63045303
Hyperkalaemia	64.25	10.68	139	51796	54064	63383023
Atrioventricular block second degree	64.22	10.68	40	51895	3874	63433213
Infusion related reaction	63.83	10.68	64	51871	245457	63191630
Arthropathy	63.60	10.68	59	51876	234733	63202354
Exposure during pregnancy	63.31	10.68	24	51911	155523	63281564
Discomfort	58.51	10.68	32	51903	167342	63269745
Duodenal ulcer perforation	55.86	10.68	4	51931	87205	63349882
Drug intolerance	53.83	10.68	107	51828	308554	63128533
Lactic acidosis	53.39	10.68	105	51830	38182	63398905
Muscle spasms	52.69	10.68	260	51675	155890	63281197
Diarrhoea	52.05	10.68	847	51088	714519	62722568
Swelling	51.05	10.68	92	51843	275286	63161801
Pulseless electrical activity	48.73	10.68	44	51891	7477	63429610
Myopathy	45.77	10.68	51	51884	11140	63425947
Bezoar	45.27	10.68	23	51912	1503	63435584
Insulin autoimmune syndrome	41.57	10.68	11	51924	103	63436984
Therapeutic product effect decreased	41.00	10.68	59	51876	193128	63243959
Hepatic enzyme increased	40.80	10.68	64	51871	202264	63234823
Full blood count decreased	40.77	10.68	75	51860	25949	63411138
Folliculitis	40.33	10.68	5	51930	70312	63366775
Joint swelling	39.26	10.68	137	51798	327529	63109558
Chronic kidney disease	39.25	10.68	103	51832	45295	63391792
Psoriasis	36.93	10.68	155	51780	86802	63350285
Decreased bronchial secretion	36.45	10.68	9	51926	62	63437025
Alopecia	35.98	10.68	148	51787	337388	63099699
Congenital coronary artery malformation	34.26	10.68	10	51925	138	63436949
Drug abuse	33.37	10.68	9	51926	72509	63364578
Drug hypersensitivity	32.64	10.68	393	51542	310294	63126793
Colitis microscopic	32.23	10.68	39	51896	9300	63427787
Blood thyroid stimulating hormone normal	31.54	10.68	9	51926	114	63436973
Impaired healing	31.16	10.68	23	51912	102519	63334568
Abdominal discomfort	30.98	10.68	146	51789	320739	63116348
Hyponatraemia	30.67	10.68	176	51759	111724	63325363
Rhabdomyolysis	30.43	10.68	92	51843	43859	63393228
Acute interstitial pneumonitis	28.10	10.68	13	51922	691	63436396
Hypersensitivity	25.49	10.68	138	51797	292547	63144540
Immune-mediated myositis	25.31	10.68	15	51920	1328	63435759
Blood glucose increased	25.12	10.68	135	51800	83621	63353466
Asthenia	24.77	10.68	446	51489	383158	63053929
Toxicity to various agents	24.74	10.68	111	51824	247139	63189948
Electrocardiogram PR prolongation	24.70	10.68	12	51923	712	63436375
Interstitial lung disease	24.47	10.68	108	51827	61800	63375287
Ill-defined disorder	23.99	10.68	19	51916	81736	63355351
Anaemia	23.70	10.68	354	51581	293076	63144011
Completed suicide	23.26	10.68	53	51882	145620	63291467
Atrioventricular block first degree	22.89	10.68	29	51906	7244	63429843
Atrial fibrillation	22.51	10.68	168	51767	116468	63320619
Rheumatoid arthritis	22.47	10.68	119	51816	253700	63183387
Gastrointestinal disorder	22.41	10.68	46	51889	131193	63305894
Muscular weakness	22.37	10.68	174	51761	122179	63314908
Decreased appetite	22.30	10.68	308	51627	250744	63186343
Musculoskeletal stiffness	22.21	10.68	77	51858	184541	63252546
Vertigo	21.82	10.68	102	51833	59785	63377302
Blister	21.74	10.68	46	51889	129768	63307319
Muscle rupture	21.40	10.68	17	51918	2426	63434661
Malaise	21.28	10.68	467	51468	415487	63021600
Hip arthroplasty	19.97	10.68	7	51928	47639	63389448
Post viral fatigue syndrome	19.69	10.68	8	51927	309	63436778
Adenocarcinoma metastatic	19.40	10.68	6	51929	102	63436985
Diabetic ketoacidosis	19.25	10.68	48	51887	20457	63416630
Red blood cell sedimentation rate increased	19.24	10.68	6	51929	43976	63393111
Memory impairment	18.90	10.68	148	51787	104110	63332977
Infection	18.88	10.68	110	51825	229063	63208024
Device expulsion	18.81	10.68	3	51932	34919	63402168
Alexithymia	18.33	10.68	3	51932	0	63437087
Pancreatic steatosis	18.24	10.68	11	51924	1005	63436082
Axonal neuropathy	18.18	10.68	11	51924	1011	63436076
Suicide attempt	18.07	10.68	14	51921	60904	63376183
Renal tubular disorder	17.99	10.68	16	51919	2666	63434421
Haematoma	17.96	10.68	66	51869	34754	63402333
Vitamin B12 decreased	17.45	10.68	18	51917	3602	63433485
Intertrigo	17.45	10.68	9	51926	607	63436480
Cerebral haemorrhage	17.35	10.68	60	51875	30669	63406418
Laryngitis	17.30	10.68	41	51894	16926	63420161
Glycosylated haemoglobin increased	17.28	10.68	34	51901	12364	63424723
Urinary tract infection	17.15	10.68	308	51627	264376	63172711
Fixed eruption	16.87	10.68	11	51924	1153	63435934
Sinus arrhythmia	16.79	10.68	12	51923	1461	63435626
Cholestatic liver injury	16.38	10.68	15	51920	2595	63434492
Hepatotoxicity	16.30	10.68	5	51930	37036	63400051
Myositis	16.17	10.68	28	51907	9238	63427849
Muscle injury	15.87	10.68	18	51917	65327	63371760
Gastrointestinal haemorrhage	15.70	10.68	117	51818	81059	63356028
Inflammation	15.66	10.68	27	51908	82246	63354841
Cerebral infarction	15.59	10.68	49	51886	23844	63413243
Blood loss anaemia	15.45	10.68	27	51908	8974	63428113
Drug interaction	15.32	10.68	268	51667	228863	63208224
Nasal congestion	15.27	10.68	99	51836	65561	63371526
Product dispensing error	15.26	10.68	29	51906	10276	63426811
Melaena	15.20	10.68	57	51878	30308	63406779
Cutaneous T-cell lymphoma	15.17	10.68	11	51924	1369	63435718
Urinary incontinence	15.12	10.68	59	51876	31955	63405132
Product use issue	15.05	10.68	112	51823	220408	63216679
Cardiac failure congestive	15.02	10.68	128	51807	92305	63344782
Hepatitis cholestatic	15.01	10.68	23	51912	6855	63430232
Restless legs syndrome	14.96	10.68	41	51894	18490	63418597
Mobility decreased	14.92	10.68	50	51885	121109	63315978
Loss of consciousness	14.91	10.68	155	51780	117966	63319121
Cardiac murmur functional	14.88	10.68	4	51931	40	63437047
Eczema	14.84	10.68	59	51876	32232	63404855
Ear haemorrhage	14.75	10.68	11	51924	1429	63435658
Pain in extremity	14.72	10.68	365	51570	331121	63105966
Viral infection	14.69	10.68	63	51872	35600	63401487
Haematoma muscle	14.68	10.68	10	51925	1127	63435960
Gastric infection	14.45	10.68	16	51919	3471	63433616
Pancreatitis acute	14.44	10.68	52	51883	27114	63409973
Scratch	14.40	10.68	22	51913	6543	63430544
Liver injury	14.35	10.68	17	51918	60503	63376584
Transient ischaemic attack	14.27	10.68	65	51870	37688	63399399
Essential hypertension	14.18	10.68	19	51916	5014	63432073
Dry gangrene	14.11	10.68	8	51927	652	63436435
Tubulointerstitial nephritis	14.09	10.68	42	51893	19861	63417226
Iron deficiency anaemia	14.01	10.68	42	51893	19927	63417160
Priapism	14.00	10.68	5	51930	135	63436952
Vessel puncture site bruise	13.99	10.68	7	51928	443	63436644
Bronchitis	13.95	10.68	160	51775	124775	63312312
Potassium wasting nephropathy	13.92	10.68	4	51931	52	63437035
Poor dental condition	13.70	10.68	7	51928	463	63436624
Pericardial haemorrhage	13.61	10.68	11	51924	1608	63435479
Loss of personal independence in daily activities	13.51	10.68	38	51897	97252	63339835
Skin depigmentation	13.41	10.68	9	51926	990	63436097
Influenza	13.41	10.68	142	51793	108580	63328507
Blood folate decreased	13.22	10.68	8	51927	736	63436351
Injury	13.08	10.68	25	51910	73222	63363865
Mammogram abnormal	13.05	10.68	8	51927	753	63436334
Bacteriuria	12.98	10.68	9	51926	1044	63436043
Ligament rupture	12.95	10.68	15	51920	3415	63433672
Heart rate abnormal	12.91	10.68	18	51917	4929	63432158
Myopathy toxic	12.91	10.68	7	51928	523	63436564
Fanconi syndrome	12.87	10.68	10	51925	1382	63435705
Dysmetria	12.82	10.68	7	51928	530	63436557
Sedation	12.73	10.68	8	51927	38801	63398286
COVID-19 immunisation	12.66	10.68	11	51924	1776	63435311
Hyperlipidaemia	12.64	10.68	40	51895	19531	63417556
Hypoacusis	12.64	10.68	46	51889	24105	63412982
Constipation	12.59	10.68	256	51679	224687	63212400
Arterial thrombosis	12.55	10.68	10	51925	1433	63435654
Hypovolaemic shock	12.42	10.68	20	51915	6221	63430866
Alanine aminotransferase	12.37	10.68	4	51931	79	63437008
Cholestasis	12.12	10.68	52	51883	29382	63407705
Uterine dilation and evacuation	12.11	10.68	3	51932	21	63437066
Off label use	12.06	10.68	441	51494	674021	62763066
General physical health deterioration	12.04	10.68	106	51829	201296	63235791
Respiratory arrest	11.75	10.68	6	51929	32639	63404448
C-reactive protein increased	11.72	10.68	39	51896	94668	63342419
Cerebral mass effect	11.72	10.68	8	51927	905	63436182
Angular cheilitis	11.57	10.68	7	51928	644	63436443
Pain	11.56	10.68	492	51443	740136	62696951
Hypochloraemia	11.56	10.68	11	51924	1998	63435089
Angina pectoris	11.52	10.68	52	51883	30026	63407061
Fibromyalgia	11.47	10.68	31	51904	80389	63356698
Lower gastrointestinal haemorrhage	11.44	10.68	22	51913	7868	63429219
Mucosal inflammation	11.32	10.68	13	51922	46915	63390172
Myxoedema	11.30	10.68	4	51931	105	63436982
Low density lipoprotein decreased	11.30	10.68	5	51930	239	63436848
Papillitis	11.25	10.68	3	51932	29	63437058
Dysgeusia	11.21	10.68	71	51864	46639	63390448
Back pain	11.17	10.68	289	51646	263856	63173231
Vitamin B6 deficiency	11.16	10.68	4	51931	109	63436978
Diabetes mellitus	11.11	10.68	81	51854	55729	63381358
Pulmonary renal syndrome	11.07	10.68	6	51929	448	63436639
Ocular retrobulbar haemorrhage	11.06	10.68	4	51931	112	63436975
Enteritis infectious	11.04	10.68	11	51924	2113	63434974
Epistaxis	10.93	10.68	99	51836	72626	63364461
Presbyopia	10.86	10.68	6	51929	465	63436622
Leukocytosis	10.82	10.68	46	51889	25889	63411198
Myelosuppression	10.79	10.68	3	51932	23700	63413387
Febrile neutropenia	10.77	10.68	55	51880	118394	63318693

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Myalgia	191.50	10.76	347	40220	83763	34832601
Acute kidney injury	72.45	10.76	602	39965	304386	34611978
IgM nephropathy	71.91	10.76	19	40548	119	34916245
Drug abuse	71.64	10.76	14	40553	99082	34817282
Blood creatine phosphokinase increased	50.66	10.76	140	40427	44717	34871647
Shone complex	50.56	10.76	13	40554	72	34916292
Myopathy	47.92	10.76	63	40504	11491	34904873
Fall	39.07	10.76	383	40184	202502	34713862
Interstitial lung disease	38.51	10.76	164	40403	65118	34851246
Drug interaction	37.12	10.76	413	40154	225533	34690831
Supravalvular aortic stenosis	35.60	10.76	9	40558	46	34916318
Aorta hypoplasia	35.29	10.76	10	40557	84	34916280
Puncture site haematoma	34.29	10.76	11	40556	146	34916218
Intestinal atony	34.08	10.76	8	40559	28	34916336
Drug ineffective	32.73	10.76	356	40211	456395	34459969
Intraocular haematoma	32.65	10.76	7	40560	14	34916350
Exercise lack of	31.65	10.76	10	40557	126	34916238
Muscle rupture	31.41	10.76	24	40543	2274	34914090
Lactic acidosis	31.15	10.76	100	40467	34672	34881692
Angina pectoris	29.75	10.76	92	40475	31271	34885093
Diaphragmatic disorder	28.46	10.76	18	40549	1257	34915107
Completed suicide	28.12	10.76	44	40523	98124	34818240
Phaeochromocytoma malignant	27.74	10.76	8	40559	72	34916292
Hepatocellular injury	25.74	10.76	70	40497	22141	34894223
Congenital heart valve disorder	25.12	10.76	7	40560	55	34916309
Cholestasis	24.59	10.76	78	40489	26870	34889494
Hyperkinetic heart syndrome	24.04	10.76	8	40559	120	34916244
Febrile neutropenia	24.03	10.76	80	40487	136769	34779595
Pemphigoid	23.92	10.76	39	40528	8627	34907737
Muscle spasms	23.91	10.76	159	40408	74842	34841522
Left ventricular hypertrophy	23.01	10.76	37	40530	8093	34908271
Off label use	22.59	10.76	347	40220	419177	34497187
Congenital aortic anomaly	22.39	10.76	7	40560	85	34916279
Gastritis fungal	22.39	10.76	7	40560	85	34916279
Mitral valve hypoplasia	22.39	10.76	6	40561	40	34916324
Coma uraemic	22.26	10.76	6	40561	41	34916323
Pericarditis fungal	22.20	10.76	8	40559	154	34916210
Renal-limited thrombotic microangiopathy	21.95	10.76	7	40560	91	34916273
Femoral artery aneurysm	21.68	10.76	8	40559	165	34916199
AST/ALT ratio abnormal	21.64	10.76	5	40562	16	34916348
Nephrogenic anaemia	21.61	10.76	19	40548	2192	34914172
Pseudolymphoma	21.58	10.76	12	40555	660	34915704
Tendon rupture	21.35	10.76	33	40534	6979	34909385
Cerebral haematoma	20.44	10.76	26	40541	4589	34911775
Cerebrovascular accident	20.31	10.76	168	40399	84643	34831721
Chest wall haematoma	20.25	10.76	8	40559	200	34916164
Treatment failure	19.94	10.76	15	40552	46682	34869682
Dependence on oxygen therapy	19.78	10.76	8	40559	213	34916151
Coarctation of the aorta	19.53	10.76	10	40557	465	34915899
Aortic occlusion	19.03	10.76	6	40561	75	34916289
Suicide attempt	18.82	10.76	11	40556	39105	34877259
Carnitine palmitoyltransferase deficiency	18.66	10.76	4	40563	8	34916356
Hyperkalaemia	18.56	10.76	141	40426	69248	34847116
Subdural haematoma	18.53	10.76	59	40508	20362	34896002
Eosinophilic pleural effusion	18.18	10.76	8	40559	264	34916100
Sepsis	18.14	10.76	116	40451	166445	34749919
Gait disturbance	17.96	10.76	164	40403	84976	34831388
Eczema	17.40	10.76	54	40513	18382	34897982
Toxicity to various agents	17.30	10.76	149	40418	200213	34716151
Xerosis	17.28	10.76	10	40557	594	34915770
Peripheral swelling	16.94	10.76	149	40418	76392	34839972
Intensive care unit acquired weakness	16.91	10.76	12	40555	1015	34915349
Haemorrhagic transformation stroke	16.74	10.76	14	40553	1509	34914855
Renal arteriosclerosis	16.68	10.76	7	40560	205	34916159
Hyperlactacidaemia	16.65	10.76	19	40548	2997	34913367
Foetal exposure during pregnancy	16.58	10.76	12	40555	38089	34878275
Neutrophil count decreased	16.52	10.76	21	40546	51083	34865281
Toxic optic neuropathy	16.52	10.76	11	40556	839	34915525
Diarrhoea	16.44	10.76	579	39988	389333	34527031
Lupus-like syndrome	16.30	10.76	18	40549	2738	34913626
Akinesia	16.02	10.76	16	40551	2168	34914196
Loss of control of legs	15.50	10.76	10	40557	723	34915641
Myotonic dystrophy	15.45	10.76	6	40561	143	34916221
Peripheral artery occlusion	15.32	10.76	14	40553	1698	34914666
Congenital aortic valve stenosis	15.15	10.76	6	40561	151	34916213
Transaminases abnormal	15.11	10.76	7	40560	261	34916103
Cell death	15.00	10.76	16	40551	2341	34914023
Heart transplant rejection	14.97	10.76	12	40555	1219	34915145
Thrombotic stroke	14.89	10.76	7	40560	270	34916094
Hypoparathyroidism	14.66	10.76	9	40558	596	34915768
Hepatitis fulminant	14.59	10.76	21	40546	4169	34912195
Anti factor VIII antibody positive	14.50	10.76	5	40562	84	34916280
Eosinophilic pneumonia	14.37	10.76	19	40548	3482	34912882
Glycosylated haemoglobin increased	14.37	10.76	37	40530	11323	34905041
Congenital aortic stenosis	14.13	10.76	5	40562	91	34916273
Acute respiratory failure	14.03	10.76	72	40495	30856	34885508
Arteriovenous fistula	13.87	10.76	11	40556	1100	34915264
Toxic epidermal necrolysis	13.78	10.76	4	40563	21642	34894722
Therapeutic drug monitoring analysis incorrectly performed	13.76	10.76	7	40560	321	34916043
Premature baby	13.71	10.76	3	40564	19630	34896734
Orthostatic tremor	13.68	10.76	3	40564	7	34916357
Dysgeusia	13.68	10.76	64	40503	26433	34889931
Fatigue	13.35	10.76	541	40026	370112	34546252
Meningitis fungal	13.25	10.76	5	40562	110	34916254
Conjunctival haemorrhage	13.20	10.76	17	40550	3038	34913326
Bladder cyst	13.04	10.76	5	40562	115	34916249
Chronic kidney disease	12.90	10.76	87	40480	41123	34875241
Blood loss anaemia	12.85	10.76	29	40538	8165	34908199
Intraventricular haemorrhage	12.74	10.76	18	40549	3513	34912851
Rhabdomyolysis	12.74	10.76	128	40439	68035	34848329
Electrocardiogram ST segment depression	12.70	10.76	15	40552	2453	34913911
Agitation	12.70	10.76	30	40537	57369	34858995
Disease progression	12.41	10.76	74	40493	108003	34808361
Hepatitis cholestatic	12.32	10.76	28	40539	7919	34908445
Brain injury	12.27	10.76	24	40543	6118	34910246
Echocardiogram abnormal	12.16	10.76	10	40557	1053	34915311
Ketonuria	12.10	10.76	8	40559	603	34915761
Hypoxic-ischaemic encephalopathy	11.98	10.76	20	40547	4512	34911852
Multiple organ dysfunction syndrome	11.94	10.76	47	40520	76519	34839845
Heart disease congenital	11.73	10.76	11	40556	1379	34914985
Drug eruption	11.73	10.76	50	40517	19848	34896516
Neutropenia	11.63	10.76	121	40446	156657	34759707
Infusion related reaction	11.52	10.76	28	40539	53029	34863335
Drug resistance	11.50	10.76	8	40559	25919	34890445
Oedema peripheral	11.44	10.76	199	40368	119613	34796751
Myoglobin urine	11.33	10.76	3	40564	19	34916345
Thrombocytopenia	11.02	10.76	122	40445	156125	34760239
Food interaction	10.98	10.76	9	40558	944	34915420
Atrial hypertrophy	10.95	10.76	3	40564	22	34916342
Limb injury	10.81	10.76	34	40533	11655	34904709
Splenic vein thrombosis	10.81	10.76	7	40560	509	34915855
Inappropriate antidiuretic hormone secretion	10.81	10.76	36	40531	12717	34903647
Gross motor delay	10.79	10.76	6	40561	330	34916034

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Myalgia	317.83	9.89	614	77204	185027	79481543
Acute kidney injury	188.65	9.89	1001	76817	518403	79148167
Synovitis	95.71	9.89	16	77802	150718	79515852
Drug abuse	95.40	9.89	21	77797	162670	79503900
Drug ineffective	94.64	9.89	643	77175	1080270	78586300
Contraindicated product administered	93.06	9.89	20	77798	157518	79509052
Fall	91.09	9.89	798	77020	486831	79179739
Hand deformity	87.91	9.89	3	77815	103916	79562654
Lactic acidosis	85.84	9.89	203	77615	70156	79596414
Hyperkalaemia	83.83	9.89	274	77544	114124	79552446
Myopathy	77.53	9.89	98	77720	20465	79646105
IgM nephropathy	75.18	9.89	19	77799	119	79666451
Treatment failure	73.85	9.89	37	77781	170449	79496121
Maternal exposure during pregnancy	71.70	9.89	22	77796	136516	79530054
Pericarditis	70.95	9.89	9	77809	104227	79562343
Infusion related reaction	65.36	9.89	77	77741	230160	79436410
Interstitial lung disease	63.89	9.89	248	77570	112352	79554218
Exposure during pregnancy	59.39	9.89	13	77805	101119	79565451
Glossodynia	59.25	9.89	14	77804	103323	79563247
Lower respiratory tract infection	59.11	9.89	26	77792	129194	79537376
Drug interaction	58.12	9.89	640	77178	414543	79252027
Muscle spasms	57.26	9.89	328	77490	174402	79492168
Systemic lupus erythematosus	56.01	9.89	24	77794	121125	79545445
Arthropathy	54.95	9.89	55	77763	177056	79489514
Completed suicide	54.25	9.89	98	77720	245669	79420901
Blood creatine phosphokinase increased	51.76	9.89	162	77656	65928	79600642
Helicobacter infection	47.48	9.89	6	77812	69698	79596872
Duodenal ulcer perforation	46.84	9.89	5	77813	66206	79600364
Wound	44.88	9.89	29	77789	116150	79550420
Joint swelling	44.63	9.89	139	77679	288507	79378063
Toxicity to various agents	43.87	9.89	237	77581	421303	79245267
Atrioventricular block second degree	41.38	9.89	43	77775	7269	79659301
Cholestasis	40.13	9.89	127	77691	51982	79614588
Rhabdomyolysis	38.75	9.89	201	77617	102930	79563640
Therapeutic product effect decreased	35.56	9.89	66	77752	163797	79502773
Diarrhoea	34.93	9.89	1114	76704	879375	78787195
Congenital coronary artery malformation	34.93	9.89	10	77808	106	79666464
Drug intolerance	34.89	9.89	136	77682	263983	79402587
Muscle rupture	34.85	9.89	29	77789	3698	79662872
Eczema	34.71	9.89	103	77715	40715	79625855
Decreased bronchial secretion	34.62	9.89	9	77809	64	79666506
Chronic kidney disease	34.53	9.89	142	77676	66012	79600558
Puncture site haematoma	34.39	9.89	11	77807	174	79666396
Swelling	33.74	9.89	104	77714	216607	79449963
Intestinal atony	33.68	9.89	8	77810	37	79666533
Hyponatraemia	33.56	9.89	292	77526	177556	79489014
Product dose omission issue	33.39	9.89	379	77439	247158	79419412
Off label use	33.30	9.89	655	77163	906560	78760010
Glycosylated haemoglobin increased	33.23	9.89	64	77754	19196	79647374
Intraocular haematoma	31.37	9.89	7	77811	23	79666547
Folliculitis	30.77	9.89	8	77810	55372	79611198
Suicide attempt	30.30	9.89	22	77796	82910	79583660
Blood thyroid stimulating hormone normal	29.83	9.89	9	77809	116	79666454
Hypersensitivity	29.19	9.89	144	77674	262095	79404475
Phaeochromocytoma malignant	29.12	9.89	8	77810	72	79666498
Full blood count decreased	29.10	9.89	74	77744	26745	79639825
Pemphigoid	29.05	9.89	53	77765	15262	79651308
Subdural haematoma	28.34	9.89	81	77737	31353	79635217
Febrile neutropenia	27.98	9.89	123	77695	230876	79435694
Hepatocellular injury	27.94	9.89	106	77712	47487	79619083
Infection	27.90	9.89	131	77687	241581	79424989
Cerebrovascular accident	27.77	9.89	252	77566	155040	79511530
Bezoar	27.41	9.89	22	77796	2666	79663904
Myositis	26.35	9.89	58	77760	19110	79647460
Blood loss anaemia	26.13	9.89	51	77767	15447	79651123
Diaphragmatic disorder	26.10	9.89	18	77800	1732	79664838
Cerebral haematoma	25.52	9.89	35	77783	7907	79658663
Angina pectoris	25.40	9.89	109	77709	51623	79614947
Shone complex	24.88	9.89	6	77812	30	79666540
Mitral valve hypoplasia	24.88	9.89	6	77812	30	79666540
Red blood cell sedimentation rate increased	24.84	9.89	7	77811	45935	79620635
Hyperkinetic heart syndrome	24.81	9.89	8	77810	130	79666440
Congenital aortic valve stenosis	24.72	9.89	6	77812	31	79666539
Aorta hypoplasia	24.56	9.89	6	77812	32	79666538
Immune-mediated myositis	24.47	9.89	23	77795	3444	79663126
Discomfort	24.34	9.89	54	77764	125563	79541007
Alopecia	24.07	9.89	130	77688	231225	79435345
Rheumatoid arthritis	24.05	9.89	113	77705	208357	79458213
Atrial fibrillation	24.03	9.89	297	77521	197589	79468981
Gait disturbance	23.74	9.89	308	77510	207198	79459372
Congenital heart valve disorder	23.42	9.89	6	77812	40	79666530
Musculoskeletal stiffness	23.17	9.89	90	77728	174918	79491652
Coma uraemic	23.16	9.89	6	77812	42	79666528
Therapy non-responder	22.97	9.89	34	77784	92271	79574299
Hepatitis cholestatic	22.65	9.89	45	77773	13807	79652763
Pericarditis fungal	22.39	9.89	8	77810	180	79666390
AST/ALT ratio abnormal	22.28	9.89	5	77813	17	79666553
Insulin autoimmune syndrome	22.09	9.89	10	77808	422	79666148
Pancreatitis acute	21.71	9.89	101	77717	49503	79617067
Hepatic enzyme increased	21.64	9.89	98	77720	182512	79484058
Femoral artery aneurysm	21.60	9.89	8	77810	200	79666370
Colitis microscopic	21.36	9.89	38	77780	10730	79655840
Heart transplant rejection	21.28	9.89	15	77803	1495	79665075
Blister	21.05	9.89	54	77764	119422	79547148
Ill-defined disorder	20.95	9.89	20	77798	65855	79600715
Pulseless electrical activity	20.79	9.89	44	77774	14116	79652454
Congenital aortic stenosis	20.73	9.89	5	77813	25	79666545
Congenital aortic anomaly	20.73	9.89	5	77813	25	79666545
Supravalvular aortic stenosis	20.73	9.89	5	77813	25	79666545
Exercise lack of	20.73	9.89	10	77808	488	79666082
Drug hypersensitivity	20.69	9.89	408	77410	298508	79368062
Coarctation of the aorta	20.59	9.89	6	77812	68	79666502
Haematoma	20.48	9.89	103	77715	52092	79614478
Toxic epidermal necrolysis	20.33	9.89	9	77809	44572	79621998
Cerebral infarction	19.99	9.89	93	77725	45583	79620987
Asthenia	19.84	9.89	646	77172	511043	79155527
Carnitine palmitoyltransferase deficiency	19.35	9.89	4	77814	8	79666562
Inflammation	19.25	9.89	39	77779	93714	79572856
Blood glucose increased	19.25	9.89	184	77634	114791	79551779
Acute interstitial pneumonitis	19.24	9.89	13	77805	1210	79665360
Melaena	19.07	9.89	113	77705	60777	79605793
Atrioventricular block first degree	18.55	9.89	39	77779	12452	79654118
Dysgeusia	18.48	9.89	107	77711	57070	79609500
Tachycardia	18.42	9.89	100	77718	177668	79488902
Impaired healing	18.40	9.89	36	77782	87619	79578951
Vertigo	18.40	9.89	123	77695	68959	79597611
Gastritis fungal	18.32	9.89	7	77811	191	79666379
Atrial hypertrophy	18.00	9.89	5	77813	47	79666523
Patent ductus arteriosus	17.99	9.89	6	77812	109	79666461
Transient ischaemic attack	17.95	9.89	100	77718	52595	79613975
Psoriasis	17.89	9.89	149	77669	89438	79577132
Eosinophilic pleural effusion	17.82	9.89	8	77810	331	79666239
Pancreatic steatosis	17.61	9.89	12	77806	1133	79665437
Toxic optic neuropathy	17.53	9.89	12	77806	1141	79665429
Metabolic acidosis	17.42	9.89	139	77679	82390	79584180
Haemorrhagic transformation stroke	17.37	9.89	17	77801	2675	79663895
Pseudolymphoma	17.05	9.89	12	77806	1193	79665377
Hyperlactacidaemia	17.00	9.89	24	77794	5571	79660999
Cardiac failure congestive	16.54	9.89	212	77606	142190	79524380
Acute respiratory failure	16.45	9.89	107	77711	59434	79607136
Intraventricular haemorrhage	16.41	9.89	22	77796	4865	79661705
Myotonic dystrophy	16.39	9.89	6	77812	145	79666425
Corneal dystrophy	16.25	9.89	7	77811	262	79666308
Hospice care	16.23	9.89	33	77785	10291	79656279
Sedation	16.21	9.89	16	77802	51879	79614691
Behaviour disorder	16.18	9.89	25	77793	6288	79660282
Laryngitis	16.11	9.89	43	77775	15996	79650574
Heart disease congenital	16.01	9.89	9	77809	603	79665967
Renal-limited thrombotic microangiopathy	15.91	9.89	6	77812	158	79666412
Tendon rupture	15.89	9.89	36	77782	12090	79654480
Myopathy toxic	15.69	9.89	11	77807	1087	79665483
Chest wall haematoma	15.68	9.89	8	77810	441	79666129
Intentional self-injury	15.67	9.89	6	77812	32413	79634157
Left ventricular failure	15.51	9.89	31	77787	9550	79657020
Anti factor VIII antibody positive	15.08	9.89	5	77813	89	79666481
Adenocarcinoma metastatic	15.02	9.89	6	77812	185	79666385
Sinus arrhythmia	14.90	9.89	14	77804	2096	79664474
Renal arteriosclerosis	14.84	9.89	7	77811	325	79666245
Cholestatic liver injury	14.72	9.89	21	77797	4920	79661650
Diabetic ketoacidosis	14.58	9.89	69	77749	34053	79632517
Post viral fatigue syndrome	14.50	9.89	7	77811	342	79666228
Injury	14.46	9.89	34	77784	77462	79589108
Bladder cyst	14.40	9.89	5	77813	103	79666467
Cerebral haemorrhage	14.36	9.89	101	77717	57572	79608998
Thrombotic stroke	14.31	9.89	9	77809	742	79665828
Anaemia	14.30	9.89	550	77268	444465	79222105
Cardiac murmur functional	14.27	9.89	4	77814	39	79666531
Electrocardiogram PR prolongation	14.15	9.89	12	77806	1571	79664999
Haematoma muscle	14.12	9.89	15	77803	2600	79663970
Low density lipoprotein increased	14.08	9.89	28	77790	8594	79657976
Pain	13.87	9.89	554	77264	703248	78963322
Fibromyalgia	13.87	9.89	26	77792	64314	79602256
Device expulsion	13.87	9.89	4	77814	25857	79640713
Loss of control of legs	13.80	9.89	13	77805	1952	79664618
Arteriovenous fistula	13.63	9.89	11	77807	1343	79665227
Mobility decreased	13.63	9.89	67	77751	122108	79544462
Eosinophilic pneumonia	13.57	9.89	21	77797	5289	79661281
Haemorrhage intracranial	13.49	9.89	56	77762	26137	79640433
Squamous cell carcinoma of skin	13.47	9.89	37	77781	13996	79652574
Subacute cutaneous lupus erythematosus	13.47	9.89	17	77801	3544	79663026
Blood glucose abnormal	13.44	9.89	31	77787	10535	79656035
Hypoparathyroidism	13.41	9.89	10	77808	1088	79665482
Axonal neuropathy	13.31	9.89	13	77805	2041	79664529
Oedema peripheral	13.22	9.89	331	77487	251957	79414613
Electrocardiogram abnormal	13.07	9.89	41	77777	16696	79649874
Gastrointestinal disorder	13.07	9.89	68	77750	122137	79544433
Restless legs syndrome	12.84	9.89	46	77772	20046	79646524
Akinesia	12.83	9.89	16	77802	3296	79663274
Hepatotoxicity	12.69	9.89	19	77799	51333	79615237
Mucosal inflammation	12.68	9.89	35	77783	75545	79591025
Fixed eruption	12.62	9.89	15	77803	2939	79663631
Glycosuria	12.62	9.89	13	77805	2175	79664395
Xerosis	12.58	9.89	10	77808	1196	79665374
Ligament rupture	12.51	9.89	16	77802	3378	79663192
Death	12.50	9.89	674	77144	565840	79100730
Bursitis	12.46	9.89	10	77808	35834	79630736
Hip arthroplasty	12.40	9.89	10	77808	35746	79630824
Mammogram abnormal	12.28	9.89	7	77811	482	79666088
Left ventricular hypertrophy	12.27	9.89	31	77787	11160	79655410
Speech disorder	12.21	9.89	93	77725	54352	79612218
Muscle haemorrhage	12.20	9.89	22	77796	6278	79660292
Cardiovascular disorder	12.15	9.89	42	77776	17983	79648587
Bacteriuria	12.11	9.89	10	77808	1261	79665309
Intensive care unit acquired weakness	12.09	9.89	12	77806	1921	79664649
Dry gangrene	12.06	9.89	9	77809	980	79665590
Electrocardiogram ST segment depression	12.06	9.89	19	77799	4859	79661711
Vessel puncture site bruise	11.98	9.89	7	77811	505	79666065
Muscle injury	11.97	9.89	18	77800	48543	79618027
Full blood count abnormal	11.97	9.89	74	77744	40400	79626170
Hypersensitivity vasculitis	11.89	9.89	23	77795	6920	79659650
Adenocarcinoma of appendix	11.87	9.89	4	77814	75	79666495
Loss of consciousness	11.86	9.89	230	77588	167713	79498857
Irritable bowel syndrome	11.86	9.89	27	77791	62214	79604356
General physical health deterioration	11.84	9.89	193	77625	275045	79391525
Pyuria	11.84	9.89	13	77805	2339	79664231
Hypokalaemia	11.84	9.89	202	77616	143838	79522732
Inappropriate antidiuretic hormone secretion	11.83	9.89	54	77764	26259	79640311
Mouth ulceration	11.81	9.89	12	77806	38382	79628188
Pericardial haemorrhage	11.80	9.89	18	77800	4477	79662093
Angular cheilitis	11.75	9.89	8	77810	754	79665816
Sopor	11.74	9.89	9	77809	33001	79633569
Decreased appetite	11.66	9.89	426	77392	341992	79324578
Uterine dilation and evacuation	11.58	9.89	3	77815	21	79666549
Product use issue	11.56	9.89	140	77678	209682	79456888
Essential hypertension	11.55	9.89	21	77797	6032	79660538
Meningitis fungal	11.46	9.89	5	77813	193	79666377
Therapy cessation	11.31	9.89	69	77749	37493	79629077
Splenic vein thrombosis	11.31	9.89	8	77810	802	79665768
Flushing	11.29	9.89	46	77772	88222	79578348
Gastric infection	11.26	9.89	16	77802	3737	79662833
Lower gastrointestinal haemorrhage	11.24	9.89	38	77780	16087	79650483
Renal failure	11.22	9.89	266	77552	200702	79465868
Therapeutic response decreased	11.18	9.89	31	77787	66822	79599748
Hepatitis fulminant	11.17	9.89	23	77795	7239	79659331
Hypoxic-ischaemic encephalopathy	11.13	9.89	24	77794	7796	79658774
Poor dental condition	11.13	9.89	7	77811	577	79665993
Intertrigo	11.12	9.89	8	77810	824	79665746
Drug resistance	11.04	9.89	15	77803	42198	79624372
Iron deficiency anaemia	11.03	9.89	52	77766	25620	79640950
Gastrointestinal haemorrhage	11.02	9.89	204	77614	147515	79519055
Loss of personal independence in daily activities	11.02	9.89	57	77761	102523	79564047
Sinusitis	10.94	9.89	130	77688	195371	79471199
Transaminases abnormal	10.86	9.89	8	77810	854	79665716
Head injury	10.85	9.89	68	77750	37301	79629269
Cutaneous lupus erythematosus	10.83	9.89	14	77804	2989	79663581
Foot deformity	10.76	9.89	5	77813	24069	79642501
Echocardiogram abnormal	10.67	9.89	12	77806	2216	79664354
Emotional distress	10.66	9.89	14	77804	39955	79626615
Ligament sprain	10.53	9.89	33	77785	13431	79653139
Hypovolaemic shock	10.46	9.89	31	77787	12245	79654325
Prostate cancer metastatic	10.46	9.89	16	77802	3991	79662579
Cerebral mass effect	10.41	9.89	11	77807	1895	79664675
Muscular weakness	10.32	9.89	217	77601	160512	79506058
Polymyalgia rheumatica	10.30	9.89	17	77801	4520	79662050
Dystonia	10.27	9.89	4	77814	21395	79645175
Cytokine release syndrome	10.24	9.89	12	77806	35986	79630584
Neurotoxicity	10.19	9.89	10	77808	32508	79634062
Tendon disorder	10.17	9.89	22	77796	7164	79659406
Scratch	10.05	9.89	24	77794	8339	79658231
Memory impairment	10.03	9.89	159	77659	111575	79554995
Blood folate decreased	9.97	9.89	9	77809	1280	79665290
Immunosuppressant drug level decreased	9.96	9.89	11	77807	1993	79664577
Product physical issue	9.93	9.89	16	77802	4169	79662401

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	C10AA03	CARDIOVASCULAR SYSTEM LIPID MODIFYING AGENTS LIPID MODIFYING AGENTS, PLAIN HMG CoA reductase inhibitors
ATC	C10BA03	CARDIOVASCULAR SYSTEM LIPID MODIFYING AGENTS LIPID MODIFYING AGENTS, COMBINATIONS Combinations of various lipid modifying agents
ATC	C10BA11	CARDIOVASCULAR SYSTEM LIPID MODIFYING AGENTS LIPID MODIFYING AGENTS, COMBINATIONS Combinations of various lipid modifying agents
ATC	C10BA12	CARDIOVASCULAR SYSTEM LIPID MODIFYING AGENTS LIPID MODIFYING AGENTS, COMBINATIONS Combinations of various lipid modifying agents
ATC	C10BX02	CARDIOVASCULAR SYSTEM LIPID MODIFYING AGENTS LIPID MODIFYING AGENTS, COMBINATIONS Lipid modifying agents in combination with other drugs
FDA MoA	N0000000121	Hydroxymethylglutaryl-CoA Reductase Inhibitors
FDA EPC	N0000175589	HMG-CoA Reductase Inhibitor
CHEBI has role	CHEBI:25212	metabolites
CHEBI has role	CHEBI:35703	Xenobiotic
CHEBI has role	CHEBI:35821	anticholesteremic drugs
CHEBI has role	CHEBI:78298	environmental contaminants
MeSH PA	D000924	Anticholesteremic Agents
MeSH PA	D000963	Antimetabolites
MeSH PA	D004791	Enzyme Inhibitors
MeSH PA	D019161	Hydroxymethylglutaryl-CoA Reductase Inhibitors
MeSH PA	D000960	Hypolipidemic Agents
MeSH PA	D057847	Lipid Regulating Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Hypercholesterolemia	indication	13644009
Arteriosclerotic vascular disease	indication	72092001
Cerebrovascular accident	indication	230690007
Familial hypercholesterolemia - heterozygous	indication	238079002
Mixed hyperlipidemia	indication	267434003
Hypertriglyceridemia	indication	302870006
Familial type 3 hyperlipoproteinemia	indication	398796005	DOID:3145
Primary Prevention of Coronary Heart Disease	indication
Prevention of Transient Ischemic Attacks	indication
Myocardial Infarction Prevention	indication
Slow Progression of Coronary Artery Disease	indication
Alcoholism	contraindication	7200002
Peptic ulcer	contraindication	13200003	DOID:750
Constipation	contraindication	14760008	DOID:2089
Sarcoidosis	contraindication	31541009	DOID:11335
Dehydration	contraindication	34095006
Gastrointestinal ulcer	contraindication	40845000
Low blood pressure	contraindication	45007003
Vitamin K deficiency	contraindication	52675005	DOID:11249
Nasal polyp	contraindication	52756005
Acute nephropathy	contraindication	58574008
Diarrhea	contraindication	62315008
Hypercalcemia	contraindication	66931009	DOID:12678
Hyperparathyroidism	contraindication	66999008	DOID:13543
Factor II deficiency	contraindication	73975000
Reye's syndrome	contraindication	74351001	DOID:14525
Gastrointestinal hemorrhage	contraindication	74474003
Thrombotic thrombocytopenic purpura	contraindication	78129009	DOID:10772
Gout	contraindication	90560007	DOID:13189
Kidney disease	contraindication	90708001	DOID:557
Hemophilia	contraindication	90935002
Kidney stone	contraindication	95570007
Anemia due to enzyme deficiency	contraindication	111577008
von Willebrand disorder	contraindication	128105004	DOID:12531
Disorder of muscle	contraindication	129565002	DOID:423
Liver function tests abnormal	contraindication	166603001
Osteolysis	contraindication	203522001
Hemorrhagic cerebral infarction	contraindication	230706003
Disease of liver	contraindication	235856003	DOID:409
Rhabdomyolysis	contraindication	240131006
Anemia	contraindication	271737000	DOID:2355
Pregnancy, function	contraindication	289908002
Thrombocytopenic disorder	contraindication	302215000	DOID:1588
Surgical procedure	contraindication	387713003
Breastfeeding (mother)	contraindication	413712001
Traumatic injury	contraindication	417746004
Acute erosive gastritis	contraindication	444926003
Uncontrolled Epilepsy	contraindication

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	4.44	acidic
pKa2	13.74	acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
3-hydroxy-3-methylglutaryl-coenzyme A reductase	Enzyme	P04035	HMDH_HUMAN	INHIBITOR	IC50	7.52		CHEMBL	CHEMBL
3-hydroxy-3-methylglutaryl-coenzyme A reductase	Enzyme		HMDH_RAT		IC50	8.38		CHEMBL
Solute carrier family 22 member 6	Transporter		S22A6_RAT		Ki	4.28		CHEMBL

External reference:

ID	Source
4020548	VUID
N0000148255	NUI
D00893	KEGG_DRUG
81131-70-6	SECONDARY_CAS_RN
4020369	VANDF
4020548	VANDF
C0085542	UMLSCUI
CHEBI:63618	CHEBI
CHEMBL1144	ChEMBL_ID
CHEMBL690	ChEMBL_ID
D017035	MESH_DESCRIPTOR_UI
DB00175	DRUGBANK_ID
54687	PUBCHEM_CID
2953	IUPHAR_LIGAND_ID
6070	INN_ID
KXO2KT9N0G	UNII
203144	RXNORM
1884	MMSL
5343	MMSL
81574	MMSL
d00348	MMSL
003606	NDDF
003607	NDDF
373566006	SNOMEDCT_US
96305006	SNOMEDCT_US
96306007	SNOMEDCT_US

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0093-0771	TABLET	10 mg	ORAL	ANDA	29 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0093-0771	TABLET	10 mg	ORAL	ANDA	29 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0093-0771	TABLET	10 mg	ORAL	ANDA	29 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0093-7201	TABLET	20 mg	ORAL	ANDA	29 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0093-7201	TABLET	20 mg	ORAL	ANDA	29 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0093-7201	TABLET	20 mg	ORAL	ANDA	29 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0093-7202	TABLET	40 mg	ORAL	ANDA	29 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0093-7202	TABLET	40 mg	ORAL	ANDA	29 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0093-7202	TABLET	40 mg	ORAL	ANDA	29 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0093-7270	TABLET	80 mg	ORAL	ANDA	29 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0093-7270	TABLET	80 mg	ORAL	ANDA	29 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0093-7270	TABLET	80 mg	ORAL	ANDA	29 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0093-7270	TABLET	80 mg	ORAL	ANDA	29 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0480-7270	TABLET	80 mg	ORAL	ANDA	25 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0615-8029	TABLET	20 mg	ORAL	ANDA	28 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0615-8029	TABLET	20 mg	ORAL	ANDA	28 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0615-8030	TABLET	40 mg	ORAL	ANDA	28 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0615-8030	TABLET	40 mg	ORAL	ANDA	28 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0615-8158	TABLET	10 mg	ORAL	ANDA	28 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0615-8158	TABLET	10 mg	ORAL	ANDA	28 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0615-8159	TABLET	80 mg	ORAL	ANDA	29 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0615-8410	TABLET	80 mg	ORAL	ANDA	28 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	0615-8410	TABLET	80 mg	ORAL	ANDA	28 sections
PRAVASTATIN SODIUM	HUMAN PRESCRIPTION DRUG LABEL	1	0781-5235	TABLET	80 mg	ORAL	ANDA	29 sections
PRAVASTATIN SODIUM	HUMAN PRESCRIPTION DRUG LABEL	1	0904-5891	TABLET	10 mg	ORAL	ANDA	28 sections
PRAVASTATIN SODIUM	HUMAN PRESCRIPTION DRUG LABEL	1	0904-5892	TABLET	20 mg	ORAL	ANDA	28 sections
PRAVASTATIN SODIUM	HUMAN PRESCRIPTION DRUG LABEL	1	0904-5893	TABLET	40 mg	ORAL	ANDA	28 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	10544-440	TABLET	10 mg	ORAL	ANDA	27 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	10544-505	TABLET	20 mg	ORAL	ANDA	27 sections
Pravastatin Sodium	HUMAN PRESCRIPTION DRUG LABEL	1	10544-507	TABLET	40 mg	ORAL	ANDA	27 sections