isothipendyl 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
vasodilators 1507 482-15-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • isothipendyl
  • dimethylaminoisopropylazaphenothiazine
  • isothipendyl hydrochloride
  • isothipendyl HCl
  • Molecular weight: 285.41
  • Formula: C16H19N3S
  • CLOGP: 4.13
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 0
  • TPSA: 19.37
  • ALOGS: -3.31
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC D04AA22 DERMATOLOGICALS
ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
Antihistamines for topical use
ATC R06AD09 RESPIRATORY SYSTEM
ANTIHISTAMINES FOR SYSTEMIC USE
ANTIHISTAMINES FOR SYSTEMIC USE
Phenothiazine derivatives
MeSH PA D018494 Histamine Agents
MeSH PA D006633 Histamine Antagonists
MeSH PA D018377 Neurotransmitter Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.25 Basic
pKa2 4.14 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01143 KEGG_DRUG
C0064088 UMLSCUI
CHEBI:135183 CHEBI
CHEMBL2111066 ChEMBL_ID
DB08802 DRUGBANK_ID
C008214 MESH_SUPPLEMENTAL_RECORD_UI
3781 PUBCHEM_CID
689 INN_ID
1225-60-1 SECONDARY_CAS_RN
WVZ7K9P0JY UNII
235726 RXNORM
003406 NDDF
004803 NDDF
CHEMBL2107246 ChEMBL_ID

Pharmaceutical products:

None