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| Stem definition | Drug id | CAS RN |
|---|---|---|
| 2025 | 3689-50-7 |
| Dose | Unit | Route |
|---|---|---|
| 30 | mg | O |
None
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,AKT2,ALK,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,CHEK1,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,ITK,JAK1,JAK2,KIT,MAP3K21,MAP3K7,MAPK12,MAPK7,MAPK9,MARK4,MET,MTOR,NTRK2,PAK4,PDK1,PDK2,PDK4,PDPK1,PIK3CB,PIM2,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK,ULK1 | 49 | |||
| kinase-selectivity-class | PDK4 | 1 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
None
None
None
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Victim of chemical submission | 69.52 | 63.35 | 10 | 438 | 869 | 110587982 |
| Poisoning | 67.95 | 63.35 | 17 | 431 | 29088 | 110559763 |
None
| Source | Code | Description |
|---|---|---|
| ATC | R06AD08 | RESPIRATORY SYSTEM ANTIHISTAMINES FOR SYSTEMIC USE ANTIHISTAMINES FOR SYSTEMIC USE Phenothiazine derivatives |
| CHEBI has role | CHEBI:51177 | antitussive |
None
None
None
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 8.92 | Basic |
| pKa2 | 3.55 | Basic |
None
None
None
| ID | Source |
|---|---|
| D07401 | KEGG_DRUG |
| C0768401 | UMLSCUI |
| CHEBI:135408 | CHEBI |
| CHEMBL2104734 | ChEMBL_ID |
| DB13820 | DRUGBANK_ID |
| C119593 | MESH_SUPPLEMENTAL_RECORD_UI |
| 19396 | PUBCHEM_CID |
| 1412 | INN_ID |
| 305MB38V1C | UNII |
| 005705 | NDDF |
None