ioxilan 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
iodine-containing contrast media 1473 107793-72-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • ioxilan
  • ioxitol
  • Molecular weight: 791.12
  • Formula: C18H24I3N3O8
  • CLOGP: -2.31
  • LIPINSKI: 3
  • HAC: 11
  • HDO: 7
  • TPSA: 179.66
  • ALOGS: -3.15
  • ROTB: 11

  • Status: OFM

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Dec. 21, 1995 FDA GUERBET

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Urticaria 71.89 61.52 18 45 147299 64351370

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC V08AB12 VARIOUS
CONTRAST MEDIA
X-RAY CONTRAST MEDIA, IODINATED
Watersoluble, nephrotropic, low osmolar X-ray contrast media
FDA MoA N0000010258 X-Ray Contrast Activity
MeSH PA D003287 Contrast Media
MeSH PA D064907 Diagnostic Uses of Chemicals
FDA EPC N0000180185 Radiographic Contrast Agent

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 10.82 acidic
pKa2 11.45 acidic
pKa3 12.2 acidic
pKa4 13.77 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4021131 VUID
N0000148585 NUI
D02161 KEGG_DRUG
4021131 VANDF
C0063829 UMLSCUI
CHEBI:135884 CHEBI
CHEMBL1201075 ChEMBL_ID
DB09135 DRUGBANK_ID
C055357 MESH_SUPPLEMENTAL_RECORD_UI
6301 INN_ID
A4YJ7J11TG UNII
3743 PUBCHEM_CID
27793 RXNORM
d06227 MMSL
007425 NDDF
409484007 SNOMEDCT_US
409485008 SNOMEDCT_US

Pharmaceutical products:

None