ioxaglic acid Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
iodine-containing contrast media 1472 59017-64-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • ioxaglic acid
  • Hexabrix 160
  • ioxaglate sodium
  • ioxaglate meglumine
  • ioxaglate
A low-osmolar, ionic contrast medium used in various radiographic procedures.
  • Molecular weight: 1268.89
  • Formula: C24H21I6N5O8
  • CLOGP: -0.84
  • LIPINSKI: 3
  • HAC: 13
  • HDO: 6
  • TPSA: 194.24
  • ALOGS: -4.92
  • ROTB: 10

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
July 26, 1985 FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
ATC V08AB03 VARIOUS
CONTRAST MEDIA
X-RAY CONTRAST MEDIA, IODINATED
Watersoluble, nephrotropic, low osmolar X-ray contrast media
FDA MoA N0000010258 X-Ray Contrast Activity
MeSH PA D003287 Contrast Media
MeSH PA D064907 Diagnostic Uses of Chemicals
FDA EPC N0000180185 Radiographic Contrast Agent
CHEBI has role CHEBI:37338 radioopaque media

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.22 acidic
pKa2 10.47 acidic
pKa3 11.47 acidic
pKa4 13.71 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000007294 NUI
D01761 KEGG_DRUG
59018-13-2 SECONDARY_CAS_RN
4018193 VANDF
4018194 VANDF
4019789 VANDF
C0022038 UMLSCUI
CHEBI:31718 CHEBI
CHEMBL1201291 ChEMBL_ID
CHEMBL1200508 ChEMBL_ID
CHEMBL1200743 ChEMBL_ID
DB09313 DRUGBANK_ID
D007485 MESH_DESCRIPTOR_UI
4217 INN_ID
75JR975T11 UNII
3742 PUBCHEM_CID
1426458 RXNORM
4910 MMSL
4911 MMSL
d03675 MMSL
000674 NDDF
000675 NDDF
003615 NDDF
353924001 SNOMEDCT_US
395760005 SNOMEDCT_US

Pharmaceutical products:

None