iobitridol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
iodine-containing contrast media 1449 136949-58-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • iobitridol
a nonionic monomeric low-osmolality contrast medium; structure given in second source
  • Molecular weight: 835.17
  • Formula: C20H28I3N3O9
  • CLOGP: -2.17
  • LIPINSKI: 3
  • HAC: 12
  • HDO: 7
  • TPSA: 191.10
  • ALOGS: -3.03
  • ROTB: 12

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Drug reaction with eosinophilia and systemic symptoms 119.95 90.27 31 238 27961 29546297

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Acute kidney injury 189.63 81.59 88 518 449152 64048974
Drug reaction with eosinophilia and systemic symptoms 158.84 81.59 45 561 54172 64443954
Rash maculo-papular 119.47 81.59 35 571 46991 64451135
Toxic skin eruption 93.93 81.59 24 582 19260 64478866
Eosinophilia 90.69 81.59 27 579 38049 64460077

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC V08AB11 VARIOUS
CONTRAST MEDIA
X-RAY CONTRAST MEDIA, IODINATED
Watersoluble, nephrotropic, low osmolar X-ray contrast media
MeSH PA D003287 Contrast Media
MeSH PA D064907 Diagnostic Uses of Chemicals

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 13.71 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01181 KEGG_DRUG
C0296806 UMLSCUI
CHEMBL2107212 ChEMBL_ID
DB12407 DRUGBANK_ID
C093233 MESH_SUPPLEMENTAL_RECORD_UI
7040 INN_ID
182ECH14UH UNII
65985 PUBCHEM_CID
87639 RXNORM
005259 NDDF
704384003 SNOMEDCT_US
715519002 SNOMEDCT_US

Pharmaceutical products:

None