citicoline 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 664 | 987-78-0 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Donor of choline in biosynthesis of choline-containing phosphoglycerides.
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Blood triglycerides increased | 79.94 | 68.04 | 19 | 238 | 13378 | 31683709 |
| Blood cholesterol increased | 75.56 | 68.04 | 19 | 238 | 16874 | 31680213 |
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Blood triglycerides increased | 77.64 | 54.87 | 20 | 541 | 19644 | 70908239 |
| Apraxia | 64.20 | 54.87 | 12 | 549 | 2671 | 70925212 |
| Perseveration | 55.11 | 54.87 | 8 | 553 | 374 | 70927509 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | N06BX06 | NERVOUS SYSTEM PSYCHOANALEPTICS PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS Other psychostimulants and nootropics |
| MeSH PA | D002491 | Central Nervous System Agents |
| MeSH PA | D018697 | Nootropic Agents |
| CHEBI has role | CHEBI:35471 | psychotropic drugs |
| CHEBI has role | CHEBI:63726 | neuroprotective agents |
| CHEBI has role | CHEBI:75771 | Mus musculus metabolites |
| CHEBI has role | CHEBI:75772 | S. cerevisiae metabolites |
| CHEBI has role | CHEBI:77746 | Homo sapiens metabolite |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 2.08 | acidic |
| pKa2 | 11.57 | acidic |
| pKa3 | 13.08 | acidic |
| pKa4 | 4.04 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| 4029346 | VUID |
| N0000180302 | NUI |
| D00057 | KEGG_DRUG |
| 1099914 | RXNORM |
| 4029346 | VANDF |
| C0010725 | UMLSCUI |
| CHEBI:16436 | CHEBI |
| CDC | PDB_CHEM_ID |
| CHEMBL1618340 | ChEMBL_ID |
| CHEMBL1256994 | ChEMBL_ID |
| CHEMBL1231700 | ChEMBL_ID |
| DB12153 | DRUGBANK_ID |
| 2290 | INN_ID |
| 33818-15-4 | SECONDARY_CAS_RN |
| 536BQ2JVC7 | UNII |
| 13804 | PUBCHEM_CID |
| 22451 | MMSL |
| d05961 | MMSL |
| 004171 | NDDF |
| 009636 | NDDF |
| 1163164009 | SNOMEDCT_US |
| 1163165005 | SNOMEDCT_US |
| 698027009 | SNOMEDCT_US |
| D003566 | MESH_DESCRIPTOR_UI |
Pharmaceutical products:
None