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| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4321 | 9005-32-7 |
| Molecule | Description |
|---|---|
|
Synonyms:
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A polysaccharide and linear copolymer, consisting mainly of beta-1,4-linked D-mannuronic acid and alpha-1,4-linked L-glucuronic acid, that occurs in marine algae such as LAMINARIA, and in BIOFILMS produced by PSEUDOMONAS AERUGINOSA.
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| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Carbuncle | 118.77 | 62.92 | 20 | 1215 | 1416 | 90625796 |
| Monoclonal immunoglobulin present | 110.95 | 62.92 | 20 | 1215 | 2104 | 90625108 |
| Hypothalamo-pituitary disorder | 109.79 | 62.92 | 20 | 1215 | 2232 | 90624980 |
| Wrist deformity | 102.54 | 62.92 | 20 | 1215 | 3218 | 90623994 |
| Overweight | 90.46 | 62.92 | 20 | 1215 | 5914 | 90621298 |
| Fibrosis | 90.40 | 62.92 | 20 | 1215 | 5932 | 90621280 |
| Nephropathy | 81.66 | 62.92 | 20 | 1215 | 9215 | 90617997 |
| Dyslipidaemia | 79.86 | 62.92 | 20 | 1215 | 10087 | 90617125 |
| Body height decreased | 76.54 | 62.92 | 20 | 1215 | 11929 | 90615283 |
| Renal cyst | 74.94 | 62.92 | 20 | 1215 | 12930 | 90614282 |
| Purpura | 72.33 | 62.92 | 20 | 1215 | 14758 | 90612454 |
| Bone density decreased | 69.16 | 62.92 | 20 | 1215 | 17325 | 90609887 |
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| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Carbuncle | 108.80 | 61.15 | 20 | 2401 | 1447 | 110585431 |
| Monoclonal immunoglobulin present | 97.84 | 61.15 | 20 | 2401 | 2520 | 110584358 |
| Hypothalamo-pituitary disorder | 95.57 | 61.15 | 20 | 2401 | 2826 | 110584052 |
| Wrist deformity | 93.31 | 61.15 | 20 | 2401 | 3169 | 110583709 |
| Catarrh | 91.45 | 61.15 | 23 | 2398 | 7312 | 110579566 |
| Burns second degree | 90.25 | 61.15 | 23 | 2398 | 7710 | 110579168 |
| Steroid dependence | 88.17 | 61.15 | 23 | 2398 | 8446 | 110578432 |
| Alcohol poisoning | 81.99 | 61.15 | 22 | 2399 | 8998 | 110577880 |
| Hypopnoea | 81.44 | 61.15 | 23 | 2398 | 11357 | 110575521 |
| Overweight | 79.25 | 61.15 | 20 | 2401 | 6444 | 110580434 |
| Parosmia | 78.10 | 61.15 | 23 | 2398 | 13157 | 110573721 |
| Fibrosis | 75.92 | 61.15 | 20 | 2401 | 7622 | 110579256 |
| Gingival pain | 74.08 | 61.15 | 23 | 2398 | 15713 | 110571165 |
| Body height decreased | 69.51 | 61.15 | 20 | 2401 | 10543 | 110576335 |
| Rhinitis | 65.96 | 61.15 | 23 | 2398 | 22522 | 110564356 |
| Nephropathy | 64.72 | 61.15 | 20 | 2401 | 13447 | 110573431 |
| Arthritis | 64.36 | 61.15 | 42 | 2379 | 167544 | 110419334 |
| Cardiac murmur | 63.97 | 61.15 | 23 | 2398 | 24605 | 110562273 |
| Dyslipidaemia | 61.37 | 61.15 | 20 | 2401 | 15945 | 110570933 |
| Bone density decreased | 61.27 | 61.15 | 20 | 2401 | 16022 | 110570856 |
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| Source | Code | Description |
|---|---|---|
| ATC | A02BX13 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR ACID RELATED DISORDERS DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD) |
| CHEBI has role | CHEBI:35480 | analgesic |
| CHEBI has role | CHEBI:49201 | anti-ulcer drug |
| CHEBI has role | CHEBI:50248 | hematologic agent |
| CHEBI has role | CHEBI:74518 | anti-obesity agent |
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| ID | Source |
|---|---|
| 4019383 | VUID |
| N0000179032 | NUI |
| D02324 | KEGG_DRUG |
| 4019383 | VANDF |
| C0051156 | UMLSCUI |
| CHEBI:17548 | CHEBI |
| CHEMBL2108894 | ChEMBL_ID |
| D000077322 | MESH_DESCRIPTOR_UI |
| DB13518 | DRUGBANK_ID |
| 8C3Z4148WZ | UNII |
| 17305 | RXNORM |
| 7454 | MMSL |
| d05227 | MMSL |
| 002434 | NDDF |
| 391734004 | SNOMEDCT_US |
| 412571008 | SNOMEDCT_US |
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