All FDA-approved EMA-approved PMDA-approved
Target Card Uniprot Example: P23975

sucralfate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definition	Drug id	CAS RN
	4106	54182-58-0

Description:

Molecule	Description
Synonyms: sucralfate antepsin carafate sucralfin sucrate sulcrate ulcerlmin ulcogant	A basic aluminum complex of sulfated sucrose. Molecular weight: Formula: None CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: ALOGS: ROTB: None

Drug dosage:

Dose	Unit	Route
4	g	O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

Date	Agency	Company	Orphan
Oct. 30, 1981	FDA	FOREST LABS INC

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Vaginal flatulence	253.28	11.86	117	36964	12521	90578845
Proctitis	244.10	11.86	121	36960	15138	90576228
Female genital tract fistula	234.53	11.86	124	36957	17744	90573622
Radiculopathy	224.87	11.86	122	36959	18383	90572983
Vaginal discharge	213.64	11.86	120	36961	19344	90572022
Chronic sinusitis	193.79	11.86	121	36960	23681	90567685
Oral candidiasis	167.58	11.86	129	36952	35326	90556040
Colitis	160.01	11.86	169	36912	69773	90521593
Haematochezia	135.63	11.86	156	36925	70757	90520609
Frequent bowel movements	130.98	11.86	138	36943	56797	90534569
Colitis ulcerative	126.22	11.86	139	36942	60127	90531239
Paraesthesia oral	123.62	11.86	103	36978	31556	90559810
Macular degeneration	120.96	11.86	110	36971	37860	90553506
Constipation	120.47	11.86	317	36764	280078	90311288
Abdominal pain	114.58	11.86	389	36692	395332	90196034
Rectal haemorrhage	108.81	11.86	151	36930	82593	90508773
Hand deformity	107.35	11.86	3	37078	296359	90295007
Maternal exposure during pregnancy	105.48	11.86	12	37069	360051	90231315
Procedural pain	105.00	11.86	96	36985	33264	90558102
Contraindicated product administered	95.46	11.86	10	37071	320129	90271237
Glossodynia	93.55	11.86	11	37070	321768	90269598
Systemic lupus erythematosus	92.37	11.86	18	37063	361878	90229488
Pericarditis	90.20	11.86	5	37076	270146	90321220
Gastritis	88.62	11.86	97	36984	41656	90549710
Nausea	88.23	11.86	763	36318	1109553	89481813
Anaemia	85.20	11.86	327	36754	352475	90238891
Gastric ulcer	73.06	11.86	72	37009	27376	90563990
Weight decreased	72.78	11.86	328	36753	379582	90211784
Cholecystitis chronic	72.61	11.86	47	37034	9779	90581587
Joint swelling	72.23	11.86	60	37021	503240	90088126
Early satiety	66.11	11.86	24	37057	1383	90589983
Wound	65.82	11.86	21	37060	302959	90288407
Helicobacter infection	65.30	11.86	8	37073	226842	90364524
Oesophagitis	60.95	11.86	53	37028	17196	90574170
Exposure during pregnancy	58.44	11.86	13	37068	238397	90352969
Hepatic enzyme increased	56.85	11.86	39	37042	360697	90230669
General physical health deterioration	56.49	11.86	38	37043	355077	90236289
Treatment failure	56.25	11.86	27	37054	303901	90287465
Arthropathy	53.32	11.86	43	37038	366199	90225167
Angina bullosa haemorrhagica	52.81	11.86	12	37069	121	90591245
Musculoskeletal stiffness	52.39	11.86	28	37053	296504	90294862
Impaired gastric emptying	50.67	11.86	42	37039	12767	90578599
Drug intolerance	47.95	11.86	68	37013	447523	90143843
Impaired healing	47.81	11.86	18	37063	234181	90357185
Type 2 diabetes mellitus	46.10	11.86	13	37068	203231	90388135
Psoriatic arthropathy	45.86	11.86	18	37063	228317	90363049
Erythema	45.39	11.86	200	36881	229046	90362320
Lower respiratory tract infection	45.26	11.86	23	37058	250636	90340730
Product use issue	45.25	11.86	41	37040	329878	90261488
Dehydration	42.63	11.86	175	36906	194272	90397094
Gastrointestinal haemorrhage	40.68	11.86	104	36977	90144	90501222
Product dose omission issue	40.41	11.86	230	36851	291457	90299909
Rheumatoid arthritis	39.91	11.86	54	37027	362560	90228806
Alopecia	38.12	11.86	92	36989	494979	90096387
Peptic ulcer	37.56	11.86	25	37056	5450	90585916
Blister	37.02	11.86	30	37051	254968	90336398
Toxicity to various agents	36.88	11.86	38	37043	287808	90303558
Facial asymmetry	36.71	11.86	14	37067	926	90590440
Therapeutic product effect decreased	36.29	11.86	36	37045	277535	90313831
Discomfort	35.39	11.86	36	37045	274299	90317067
Muscle swelling	34.92	11.86	12	37069	588	90590778
Haematemesis	34.87	11.86	55	37026	33671	90557695
Irritable bowel syndrome	34.60	11.86	21	37060	207427	90383939
Reflux gastritis	34.51	11.86	15	37066	1389	90589977
Hypersensitivity	32.29	11.86	88	36993	454589	90136777
Dyspepsia	32.00	11.86	163	36918	197997	90393369
Swelling	31.36	11.86	79	37002	418979	90172387
Urinary tract infection	31.18	11.86	223	36858	305409	90285957
Cholelithiasis	30.72	11.86	67	37014	52439	90538927
Bursitis	30.64	11.86	8	37073	131646	90459720
Gastrooesophageal reflux disease	30.57	11.86	142	36939	166195	90425171
Ill-defined disorder	30.44	11.86	19	37062	184872	90406494
Mobility decreased	30.01	11.86	35	37046	250699	90340667
Headache	29.88	11.86	507	36574	862239	89729127
Facet joint syndrome	29.49	11.86	3	37078	98386	90492980
Gallbladder disorder	28.84	11.86	38	37043	19765	90571601
Cellulitis	28.29	11.86	92	36989	91245	90500121
Intentional overdose	27.76	11.86	3	37078	93831	90497535
Tarsal tunnel syndrome	27.70	11.86	10	37071	567	90590799
Grip strength decreased	27.29	11.86	3	37078	92573	90498793
Hiatus hernia	27.11	11.86	42	37039	25319	90566047
Fibromyalgia	26.67	11.86	27	37054	206242	90385124
Malaise	26.29	11.86	360	36721	585626	90005740
Drug ineffective	26.25	11.86	404	36677	1383894	89207472
Wheezing	25.63	11.86	36	37045	238044	90353322
Diarrhoea	25.63	11.86	532	36549	938658	89652708
Vulval disorder	25.55	11.86	12	37069	1332	90590034
Faeces discoloured	25.20	11.86	37	37044	21283	90570083
Oesophageal ulcer	25.00	11.86	19	37062	5100	90586266
Haemoglobin decreased	24.60	11.86	131	36950	161825	90429541
C-reactive protein increased	24.31	11.86	23	37058	181366	90410000
Wound infection	23.76	11.86	7	37074	106395	90484971
Hypercholesterolaemia	23.73	11.86	6	37075	100886	90490480
Back pain	23.41	11.86	215	36866	316960	90274406
Gait inability	22.82	11.86	16	37065	146440	90444926
Genotype drug resistance test positive	22.38	11.86	8	37073	441	90590925
Paranoia	22.34	11.86	27	37054	12881	90578485
Vascular rupture	22.02	11.86	12	37069	1821	90589545
External ear cellulitis	21.64	11.86	7	37074	284	90591082
Bronchitis	21.42	11.86	121	36960	152806	90438560
Liver injury	21.29	11.86	23	37058	170544	90420822
Red blood cell sedimentation rate increased	21.27	11.86	4	37077	82591	90508775
Blood alkaline phosphatase increased	21.24	11.86	55	37026	48024	90543342
Hip arthroplasty	21.17	11.86	3	37078	76205	90515161
Confusional state	21.01	11.86	84	36997	386121	90205245
Blood cholesterol increased	20.88	11.86	33	37048	207979	90383387
Rash	20.75	11.86	217	36864	795883	89795483
Oesophageal stenosis	20.43	11.86	15	37066	3821	90587545
Purpura senile	19.93	11.86	8	37073	607	90590759
Tendon injury	19.72	11.86	12	37069	2241	90589125
Dysphagia	19.27	11.86	94	36987	112184	90479182
Movement disorder	19.27	11.86	39	37042	28980	90562386
Overdose	18.88	11.86	22	37059	157687	90433679
Stomatitis	18.86	11.86	54	37027	274644	90316722
Urticaria	18.31	11.86	66	37015	312668	90278698
Vitamin B1 deficiency	18.23	11.86	7	37074	472	90590894
Blood magnesium decreased	18.21	11.86	27	37054	15666	90575700
Biliary dyskinesia	18.15	11.86	12	37069	2587	90588779
Burning sensation	17.95	11.86	62	37019	63390	90527976
Pancreatitis	17.85	11.86	66	37015	69760	90521606
Gastric polyps	17.82	11.86	15	37066	4657	90586709
Pulmonary fibrosis	17.75	11.86	11	37070	107492	90483874
Blood pressure diastolic increased	17.62	11.86	24	37057	12882	90578484
Drug abuse	17.35	11.86	6	37075	82341	90509025
Gastrointestinal ulcer	17.29	11.86	12	37069	2799	90588567
Liver abscess	17.12	11.86	13	37068	3483	90587883
Limb injury	17.07	11.86	39	37042	31469	90559897
Cough	17.05	11.86	228	36853	368734	90222632
Gallbladder injury	16.95	11.86	9	37072	1297	90590069
Upper gastrointestinal haemorrhage	16.61	11.86	32	37049	22944	90568422
Illness	16.57	11.86	72	37009	81897	90509469
Hallucination, auditory	16.44	11.86	26	37055	15949	90575417
Feeling abnormal	16.44	11.86	121	36960	167114	90424252
Keratomileusis	16.00	11.86	5	37076	181	90591185
Flatulence	15.94	11.86	45	37036	41322	90550044
Odynophagia	15.79	11.86	19	37062	9024	90582342
Epilepsy	15.66	11.86	7	37074	82199	90509167
Economic problem	15.63	11.86	12	37069	3269	90588097
Vestibular disorder	15.51	11.86	9	37072	1540	90589826
Upper respiratory tract infection	15.07	11.86	97	36984	128221	90463145
Inappropriate schedule of product administration	15.03	11.86	109	36972	149824	90441542
Prescribed underdose	14.91	11.86	6	37075	75013	90516353
Limb mass	14.86	11.86	12	37069	3516	90587850
Abdominal pain upper	14.72	11.86	204	36877	332470	90258896
Resorption bone increased	14.70	11.86	8	37073	1211	90590155
Inflammation	14.67	11.86	32	37049	178560	90412806
Vomiting	14.65	11.86	424	36657	787869	89803497
Intentional product use issue	14.62	11.86	43	37038	216849	90374517
Crepitations	14.49	11.86	18	37063	8834	90582532
Vocal cord operation	14.41	11.86	4	37077	95	90591271
Fear	14.35	11.86	25	37056	16597	90574769
Dysuria	14.35	11.86	42	37039	39359	90552007
Chronic obstructive pulmonary disease	14.27	11.86	64	37017	73765	90517601
Gastric haemorrhage	14.20	11.86	16	37065	7087	90584279
Adjustment disorder with depressed mood	14.09	11.86	3	37078	56750	90534616
Lung disorder	13.91	11.86	25	37056	149858	90441508
Musculoskeletal pain	13.81	11.86	31	37050	171220	90420146
Pharyngeal cyst	13.75	11.86	4	37077	113	90591253
Nasopharyngitis	13.64	11.86	104	36977	407000	90184366
Pyrexia	13.60	11.86	360	36721	660125	89931241
Obesity	13.42	11.86	14	37067	105493	90485873
Infusion site swelling	13.36	11.86	20	37061	11700	90579666
Suture insertion	13.34	11.86	5	37076	315	90591051
Cholecystectomy	13.32	11.86	20	37061	11735	90579631
Thiopurine methyltransferase decreased	13.30	11.86	5	37076	318	90591048
Hypersomnia	13.19	11.86	28	37053	21503	90569863
AST/ALT ratio abnormal	13.19	11.86	4	37077	131	90591235
Death	13.18	11.86	261	36820	456290	90135076
Knee arthroplasty	13.07	11.86	9	37072	83173	90508193
Nail disorder	12.98	11.86	4	37077	59063	90532303
Pancreatic enzyme abnormality	12.96	11.86	3	37078	33	90591333
Pain	12.72	11.86	513	36568	995828	89595538
Chills	12.69	11.86	95	36986	131886	90459480
Lip ulceration	12.58	11.86	9	37072	2203	90589163
Angiodysplasia	12.56	11.86	6	37075	692	90590674
Gastroenteritis	12.46	11.86	33	37048	29196	90562170
Abdominal discomfort	12.45	11.86	130	36951	477198	90114168
Sciatica	12.29	11.86	14	37067	101368	90489998
Pregnancy	12.27	11.86	5	37076	62042	90529324
Ocular neoplasm	12.21	11.86	5	37076	399	90590967
Haematocrit decreased	11.94	11.86	41	37040	41791	90549575
Intentional dose omission	11.92	11.86	24	37057	17759	90573607
Synovial cyst	11.92	11.86	19	37062	11733	90579633
Completed suicide	11.91	11.86	26	37055	145032	90446334

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Gastrointestinal haemorrhage	61.24	12.02	120	15481	97606	42508128
Oesophagitis	42.44	12.02	39	15562	15208	42590526
Gastrooesophageal reflux disease	40.75	12.02	65	15536	44958	42560776
Enterococcus test positive	40.01	12.02	17	15584	1668	42604066
Blood aluminium increased	39.05	12.02	6	15595	3	42605731
Dysphagia	26.33	12.02	72	15529	72647	42533087
Oesophageal ulcer	24.64	12.02	16	15585	3743	42601991
Vomiting	24.19	12.02	185	15416	289538	42316196
Off label use	23.82	12.02	137	15464	638198	41967536
Brugada syndrome	22.95	12.02	10	15591	1043	42604691
Asthma-chronic obstructive pulmonary disease overlap syndrome	22.12	12.02	11	15590	1548	42604186
Nausea	21.67	12.02	231	15370	396568	42209166
Gastric mucosal calcinosis	20.74	12.02	3	15598	0	42605734
Pneumonia	20.43	12.02	240	15361	421909	42183825
Decreased appetite	20.00	12.02	130	15471	193007	42412727
Toxicity to various agents	19.25	12.02	34	15567	229102	42376632
Abdominal pain upper	19.05	12.02	70	15531	82539	42523195
Completed suicide	18.70	12.02	6	15595	96459	42509275
Hypogonadism	17.54	12.02	11	15590	2423	42603311
Ulcer haemorrhage	17.27	12.02	12	15589	3138	42602596
Mucosal erosion	17.01	12.02	8	15593	997	42604737
Dyspepsia	16.02	12.02	42	15559	41310	42564424
Fatigue	15.78	12.02	235	15366	435406	42170328
Blood immunoglobulin E increased	15.76	12.02	12	15589	3613	42602121
Discoloured vomit	15.75	12.02	7	15594	765	42604969
Drug ineffective	15.47	12.02	152	15449	630045	41975689
Gastric haemorrhage	15.19	12.02	19	15582	10496	42595238
Dehydration	15.01	12.02	96	15505	141671	42464063
Oesophageal dilatation	15.00	12.02	5	15596	250	42605484
Abdominal pain	14.96	12.02	120	15481	190351	42415383
Sputum increased	14.93	12.02	11	15590	3152	42602582
Haemoglobin decreased	14.83	12.02	91	15510	132380	42473354
Escherichia infection	13.99	12.02	19	15582	11377	42594357
Urine phosphorus increased	13.71	12.02	4	15597	128	42605606
Gastritis	13.30	12.02	28	15573	23919	42581815
Asthenia	13.26	12.02	159	15442	280634	42325100
Joint dislocation reduction	13.06	12.02	3	15598	36	42605698
Melaena	12.68	12.02	37	15564	38709	42567025
Bezoar	12.42	12.02	7	15594	1269	42604465
Muscle twitching	12.04	12.02	18	15583	11762	42593972
Haematemesis	12.03	12.02	31	15570	30168	42575566

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Vaginal flatulence	208.06	11.49	99	42456	12045	110534699
Proctitis	199.12	11.49	107	42448	16820	110529924
Female genital tract fistula	198.75	11.49	106	42449	16413	110530331
Chronic sinusitis	187.20	11.49	118	42437	24966	110521778
Vaginal discharge	182.56	11.49	103	42452	17805	110528939
Macular degeneration	179.69	11.49	109	42446	21550	110525194
Radiculopathy	175.21	11.49	103	42452	19233	110527511
Oral candidiasis	140.11	11.49	125	42430	44635	110502109
Paraesthesia oral	127.75	11.49	105	42450	33566	110513178
Colitis	124.14	11.49	174	42381	102149	110444595
Procedural pain	108.70	11.49	98	42457	35467	110511277
Abdominal pain	96.62	11.49	422	42133	512567	110034177
Constipation	95.72	11.49	329	42226	357457	110189287
Haematochezia	93.41	11.49	163	42392	115361	110431383
Frequent bowel movements	91.98	11.49	125	42430	71265	110475479
Nausea	85.69	11.49	786	41769	1234904	109311840
Colitis ulcerative	82.80	11.49	124	42431	77239	110469505
Oesophagitis	77.82	11.49	74	42481	28641	110518103
Gastrointestinal haemorrhage	77.20	11.49	186	42369	165332	110381412
Hand deformity	71.16	11.49	3	42552	218503	110328241
Maternal exposure during pregnancy	70.12	11.49	8	42547	254875	110291869
Gastritis	69.13	11.49	94	42461	53605	110493139
Rectal haemorrhage	67.35	11.49	145	42410	119688	110427056
Weight decreased	66.36	11.49	355	42200	467702	110079042
Pericarditis	65.26	11.49	5	42550	219109	110327635
Systemic lupus erythematosus	65.15	11.49	10	42545	254328	110292416
Contraindicated product administered	63.05	11.49	10	42545	248257	110298487
Early satiety	59.77	11.49	24	42531	1939	110544805
Cholecystitis chronic	59.38	11.49	40	42515	9460	110537284
Anaemia	57.08	11.49	383	42172	546703	110000041
Folliculitis	52.35	11.49	3	42552	167650	110379094
Toxicity to various agents	52.13	11.49	65	42490	480490	110066254
Psoriatic arthropathy	52.10	11.49	7	42548	196754	110349990
Glossodynia	51.95	11.49	11	42544	221993	110324751
Gastric ulcer	51.69	11.49	70	42485	39757	110506987
Helicobacter infection	49.30	11.49	6	42549	181871	110364873
Dyspepsia	48.73	11.49	173	42382	190792	110355952
Gastrooesophageal reflux disease	45.02	11.49	162	42393	179814	110366930
Blood aluminium increased	43.71	11.49	7	42548	6	110546738
Drug intolerance	43.02	11.49	56	42499	406456	110140288
Joint swelling	42.89	11.49	65	42490	442780	110103964
Oesophageal ulcer	41.51	11.49	30	42525	7934	110538810
Impaired gastric emptying	41.38	11.49	37	42518	13238	110533506
General physical health deterioration	40.63	11.49	63	42492	425232	110121512
Angina bullosa haemorrhagica	37.85	11.49	10	42545	209	110546535
Exposure during pregnancy	37.75	11.49	9	42546	167415	110379329
Wound	37.22	11.49	22	42533	234415	110312329
Dehydration	36.86	11.49	208	42347	279303	110267441
Haematemesis	36.08	11.49	74	42481	59034	110487710
Musculoskeletal stiffness	35.72	11.49	33	42522	279789	110266955
Type 2 diabetes mellitus	35.39	11.49	12	42543	177220	110369524
Reflux gastritis	34.48	11.49	15	42540	1481	110545263
Hepatic enzyme increased	34.15	11.49	44	42511	320848	110225896
Treatment failure	33.86	11.49	34	42521	277200	110269544
Overdose	31.74	11.49	26	42529	233768	110312976
Haemoglobin decreased	31.41	11.49	183	42372	248544	110298200
Dysphagia	30.85	11.49	129	42426	153471	110393273
Lower respiratory tract infection	30.63	11.49	29	42526	243077	110303667
Enterococcus test positive	30.40	11.49	17	42538	2887	110543857
Facial asymmetry	30.02	11.49	12	42543	958	110545786
Product dose omission issue	29.81	11.49	219	42336	321563	110225181
Therapeutic product effect decreased	29.79	11.49	30	42525	244286	110302458
Erythema	29.70	11.49	203	42352	291244	110255500
Completed suicide	29.29	11.49	30	42525	242351	110304393
Arthropathy	29.00	11.49	41	42514	287481	110259263
Product use issue	28.97	11.49	47	42508	311648	110235096
Intentional overdose	28.19	11.49	8	42547	132493	110414251
Peptic ulcer	27.31	11.49	23	42532	7596	110539148
Vomiting	27.00	11.49	496	42059	910179	109636565
Hypersensitivity	26.61	11.49	74	42481	403924	110142820
Bursitis	25.58	11.49	9	42546	129909	110416835
Impaired healing	25.33	11.49	23	42532	196694	110350050
Rheumatoid arthritis	25.28	11.49	48	42507	299565	110247179
Cholelithiasis	25.09	11.49	67	42488	63355	110483389
Vulval disorder	23.84	11.49	10	42545	903	110545841
Oesophageal stenosis	23.65	11.49	18	42537	5147	110541597
Blood alkaline phosphatase increased	23.24	11.49	70	42485	70865	110475879
C-reactive protein increased	23.05	11.49	30	42525	217889	110328855
Diarrhoea	22.68	11.49	586	41969	1138919	109407825
Drug abuse	22.54	11.49	21	42534	177390	110369354
Muscle swelling	22.18	11.49	10	42545	1075	110545669
Fibromyalgia	21.98	11.49	20	42535	170889	110375855
Tarsal tunnel syndrome	21.29	11.49	8	42547	541	110546203
Prescribed overdose	21.19	11.49	4	42551	87577	110459167
Hiatus hernia	21.07	11.49	38	42517	27568	110519176
Mobility decreased	20.95	11.49	37	42518	237385	110309359
Grip strength decreased	20.87	11.49	3	42552	80171	110466573
Drug ineffective	20.53	11.49	438	42117	1520102	109026642
Purpura senile	20.40	11.49	8	42547	607	110546137
Alopecia	20.35	11.49	72	42483	364681	110182063
Headache	20.31	11.49	463	42092	881914	109664830
Off label use	20.29	11.49	432	42123	1499753	109046991
Gallbladder disorder	20.09	11.49	32	42523	20997	110525747
Vitamin B1 deficiency	20.02	11.49	9	42546	961	110545783
Melaena	19.90	11.49	65	42490	68692	110478052
Upper gastrointestinal haemorrhage	19.89	11.49	53	42502	50043	110496701
Urticaria	19.82	11.49	60	42495	318797	110227947
Swelling	19.78	11.49	69	42486	350972	110195772
Urinary tract infection	19.68	11.49	202	42353	326080	110220664
Biliary dyskinesia	19.60	11.49	12	42543	2409	110544335
Malaise	19.55	11.49	365	42190	671454	109875290
Tendon injury	19.48	11.49	12	42543	2437	110544307
Bronchitis	19.47	11.49	115	42440	156917	110389827
Gastric haemorrhage	19.19	11.49	27	42528	15888	110530856
Irritable bowel syndrome	19.08	11.49	21	42534	164194	110382550
Hypogonadism	19.06	11.49	11	42544	1983	110544761
Lung disorder	18.82	11.49	25	42530	180022	110366722
Cholecystectomy	18.81	11.49	22	42533	10787	110535957
Cellulitis	18.77	11.49	97	42458	125919	110420825
Gastrointestinal pain	18.77	11.49	23	42532	11837	110534907
Confusional state	18.62	11.49	105	42450	468575	110078169
Brugada syndrome	18.56	11.49	10	42545	1578	110545166
Product use in unapproved indication	18.44	11.49	99	42456	447278	110099466
Feeding disorder	18.38	11.49	31	42524	21331	110525413
Blood potassium decreased	18.29	11.49	54	42501	54060	110492684
External ear cellulitis	18.19	11.49	6	42549	276	110546468
Red blood cell sedimentation rate increased	18.06	11.49	4	42551	78298	110468446
Back pain	17.54	11.49	219	42336	370777	110175967
Vascular rupture	17.16	11.49	10	42545	1836	110544908
Abdominal pain upper	16.90	11.49	207	42348	348904	110197840
Keratomileusis	16.84	11.49	5	42550	162	110546582
Discomfort	16.74	11.49	36	42519	214671	110332073
Faeces discoloured	16.73	11.49	39	42516	33909	110512835
Hypercholesterolaemia	16.71	11.49	7	42548	90830	110455914
Wheezing	16.61	11.49	47	42508	255183	110291561
Epilepsy	16.48	11.49	9	42546	100200	110446544
Gastric polyps	16.44	11.49	15	42540	5508	110541236
Condition aggravated	16.15	11.49	193	42362	734643	109812101
Gastric disorder	16.09	11.49	38	42517	33319	110513425
Pneumonia	16.01	11.49	446	42109	876268	109670476
Liver injury	15.61	11.49	21	42534	150392	110396352
Crepitations	15.53	11.49	20	42535	10815	110535929
Wound infection	15.38	11.49	9	42546	96456	110450288
Ill-defined disorder	15.18	11.49	23	42532	156830	110389914
Intentional product use issue	15.15	11.49	47	42508	247859	110298885
Paranoia	14.83	11.49	29	42526	22345	110524399
Vein disorder	14.82	11.49	15	42540	6255	110540489
Blister	14.70	11.49	42	42513	227334	110319410
Cough	14.53	11.49	254	42301	461387	110085357
Vocal cord operation	14.38	11.49	4	42551	102	110546642
Upper respiratory tract infection	14.28	11.49	93	42462	131235	110415509
Pharyngeal cyst	14.27	11.49	4	42551	105	110546639
Pain	14.27	11.49	474	42081	954481	109592263
Limb mass	14.27	11.49	12	42543	3957	110542787
Odynophagia	14.23	11.49	22	42533	14079	110532665
Genotype drug resistance test positive	14.09	11.49	8	42547	1398	110545346
Discoloured vomit	13.83	11.49	9	42546	2008	110544736
Inflammation	13.77	11.49	34	42521	193204	110353540
Hypophagia	13.68	11.49	48	42507	52578	110494166
Oesophageal dilatation	13.62	11.49	6	42549	611	110546133
Blood cholesterol increased	13.57	11.49	32	42523	184753	110361991
Gastrointestinal ulcer	13.53	11.49	12	42543	4248	110542496
Resorption bone increased	13.44	11.49	8	42547	1526	110545218
Thiopurine methyltransferase decreased	13.36	11.49	5	42550	334	110546410
Blood chloride decreased	13.34	11.49	17	42538	9098	110537646
Flatulence	13.08	11.49	47	42508	52102	110494642
Suture insertion	13.04	11.49	5	42550	357	110546387
AST/ALT ratio abnormal	12.93	11.49	4	42551	149	110546595
Lymphocytosis	12.89	11.49	13	42542	5398	110541346
Urine phosphorus increased	12.45	11.49	4	42551	169	110546575
Ocular neoplasm	12.38	11.49	5	42550	410	110546334
Short-bowel syndrome	12.30	11.49	6	42549	770	110545974
Burning sensation	12.26	11.49	56	42499	69156	110477588
Sputum increased	12.23	11.49	13	42542	5738	110541006
Drug-induced liver injury	12.22	11.49	17	42538	120050	110426694
Drug hypersensitivity	12.09	11.49	114	42441	453976	110092768
Haematocrit decreased	12.09	11.49	54	42501	66063	110480681
Gastric ulcer haemorrhage	11.98	11.49	17	42538	10077	110536667
Anaemia of chronic disease	11.98	11.49	10	42545	3262	110543482
Pancreatitis	11.91	11.49	69	42486	93464	110453280
Drug interaction	11.90	11.49	129	42426	500054	110046690
Synovial cyst	11.77	11.49	18	42537	11412	110535332
Pyrexia	11.71	11.49	439	42116	897826	109648918
Vestibular disorder	11.67	11.49	9	42546	2623	110544121
Gastroenteritis	11.51	11.49	37	42518	38763	110507981
Blood loss anaemia	11.51	11.49	23	42532	18002	110528742

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	A02BX02	ALIMENTARY TRACT AND METABOLISM DRUGS FOR ACID RELATED DISORDERS DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD)
FDA CS	M0015420	Organometallic Compounds
MeSH PA	D000897	Anti-Ulcer Agents
MeSH PA	D005765	Gastrointestinal Agents
FDA EPC	N0000175801	Aluminum Complex
CHEBI has role	CHEBI:49201	anti-ulcer drug

Related Drugs by ATC class:

A02BX Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD) 15 drugs

acetoxolonealginic acidbismuth subcitratebismuth subnitratecarbenoxolonegefarnateirsogladinemethiosulfonium chloridepirenzepineproglumiderebamipidesulglicotide show all 15 →

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Duodenal ulcer disease	indication	51868009	DOID:1724
Maintenance of Healing Duodenal Ulcer	indication
Gingivostomatitis	off-label use	20607006
Peptic reflux disease	off-label use	57643001
Stomatitis	off-label use	61170000	DOID:9637
Gastroesophageal reflux disease	off-label use	235595009	DOID:8534
Gastric ulcer	off-label use	397825006	DOID:10808
NSAID-Induced Duodenal Ulcer	off-label use
Sclerotherapy Induced Esophageal Ulcer	off-label use
Stress-Related GI Mucosal Bleeding Prevention	off-label use
Maintenance of Healing Gastric Ulcer	off-label use
Prevention of Stress Ulcer	off-label use
Sclerotherapy-Induced Mucositis	off-label use
End stage renal disease	contraindication	46177005	DOID:784
Hyperglycemia	contraindication	80394007	DOID:4195
Aluminum intoxication	contraindication	236546003

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Pepsin A-5	Enzyme	P0DJD9	PEPA5_HUMAN	INHIBITOR				CHEMBL	CHEMBL

External reference:

ID	Source
4018816	VUID
N0000147119	NUI
4018816	VANDF
C0038633	UMLSCUI
CHEBI:9313	CHEBI
CHEMBL6067980	ChEMBL_ID
D013392	MESH_DESCRIPTOR_UI
DB00364	DRUGBANK_ID
7055	IUPHAR_LIGAND_ID
2723	INN_ID
XX73205DH5	UNII
10156	RXNORM
1948	MMSL
476	MMSL
5518	MMSL
d00377	MMSL
001132	NDDF
387387008	SNOMEDCT_US
69967001	SNOMEDCT_US
121494085	PUBCHEM_CID

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	0093-2210	TABLET	1 g	ORAL	ANDA	20 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	0121-0974	SUSPENSION	1 g	ORAL	ANDA	17 sections
sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	0378-9205	SUSPENSION	1 g	ORAL	ANDA	20 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	0615-4517	TABLET	1 g	ORAL	ANDA	20 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	0615-8653	TABLET	1 g	ORAL	ANDA	12 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	0713-0791	SUSPENSION	1 g	ORAL	ANDA	19 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	0904-7470	SUSPENSION	1 g	ORAL	ANDA	17 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	13668-754	SUSPENSION	1 g	ORAL	ANDA	18 sections
SUCRALFATE	HUMAN PRESCRIPTION DRUG LABEL	1	16590-523	TABLET	1 g	ORAL	ANDA	2 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	17856-0062	SUSPENSION	1 g	ORAL	ANDA	18 sections
Carafate	HUMAN PRESCRIPTION DRUG LABEL	1	17856-0170	SUSPENSION	1 g	ORAL	NDA	19 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	17856-0306	SUSPENSION	1 g	ORAL	ANDA	17 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	29033-003	TABLET	1 g	ORAL	ANDA	18 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	42291-781	SUSPENSION	1 g	ORAL	ANDA	18 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	42291-936	TABLET	1 g	ORAL	ANDA	17 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	43353-061	TABLET	1 g	ORAL	NDA	18 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	48433-091	TABLET	1 g	ORAL	ANDA	20 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	48433-226	SUSPENSION	1 g	ORAL	ANDA	19 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	50090-3019	TABLET	1 g	ORAL	ANDA	20 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	50090-5287	TABLET	1 g	ORAL	NDA authorized generic	18 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	50090-6455	TABLET	1 g	ORAL	ANDA	18 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	50268-745	SUSPENSION	1 g	ORAL	ANDA	18 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	50742-386	SUSPENSION	1 g	ORAL	ANDA	18 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	51079-753	TABLET	1 g	ORAL	ANDA	20 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	51407-881	TABLET	1 g	ORAL	ANDA	18 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	51655-031	TABLET	1 g	ORAL	ANDA	20 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	51655-475	TABLET	1 g	ORAL	NDA authorized generic	18 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	52817-840	SUSPENSION	1 g	ORAL	ANDA	18 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	53002-4930	TABLET	1 g	ORAL	ANDA	20 sections
Sucralfate	HUMAN PRESCRIPTION DRUG LABEL	1	53808-0593	TABLET	1 g	ORAL	NDA	18 sections