Stem definition | Drug id | CAS RN |
---|---|---|
4106 | 54182-58-0 |
Molecule | Description |
---|---|
Synonyms:
|
A basic aluminum complex of sulfated sucrose.
|
Dose | Unit | Route |
---|---|---|
4 | g | O |
None
Date | Agency | Company | Orphan |
---|---|---|---|
Oct. 30, 1981 | FDA | FOREST LABS INC |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Vaginal flatulence | 119.24 | 12.00 | 48 | 29280 | 3245 | 63456449 |
Proctitis | 108.10 | 12.00 | 52 | 29276 | 5389 | 63454305 |
Female genital tract fistula | 94.69 | 12.00 | 53 | 29275 | 7506 | 63452188 |
Radiculopathy | 88.27 | 12.00 | 53 | 29275 | 8558 | 63451136 |
Vaginal discharge | 80.03 | 12.00 | 51 | 29277 | 9147 | 63450547 |
Maternal exposure during pregnancy | 78.83 | 12.00 | 6 | 29322 | 220056 | 63239638 |
Drug ineffective | 73.18 | 12.00 | 244 | 29084 | 1044521 | 62415173 |
Contraindicated product administered | 72.44 | 12.00 | 8 | 29320 | 217640 | 63242054 |
Abdominal pain | 66.51 | 12.00 | 290 | 29038 | 293166 | 63166528 |
Cholecystitis chronic | 65.18 | 12.00 | 47 | 29281 | 10314 | 63449380 |
Frequent bowel movements | 65.17 | 12.00 | 66 | 29262 | 22956 | 63436738 |
Gastritis | 63.22 | 12.00 | 82 | 29246 | 37221 | 63422473 |
Hand deformity | 61.14 | 12.00 | 3 | 29325 | 159454 | 63300240 |
Colitis ulcerative | 56.63 | 12.00 | 65 | 29263 | 26026 | 63433668 |
Joint swelling | 55.72 | 12.00 | 42 | 29286 | 327624 | 63132070 |
Oral candidiasis | 53.24 | 12.00 | 59 | 29269 | 22739 | 63436955 |
Colitis | 52.12 | 12.00 | 86 | 29242 | 48442 | 63411252 |
Glossodynia | 51.60 | 12.00 | 10 | 29318 | 178866 | 63280828 |
Nausea | 50.61 | 12.00 | 609 | 28719 | 853862 | 62605832 |
Angina bullosa haemorrhagica | 50.41 | 12.00 | 12 | 29316 | 132 | 63459562 |
Systemic lupus erythematosus | 50.10 | 12.00 | 17 | 29311 | 208901 | 63250793 |
Pericarditis | 48.81 | 12.00 | 3 | 29325 | 131576 | 63328118 |
Toxicity to various agents | 46.98 | 12.00 | 28 | 29300 | 247222 | 63212472 |
Oesophagitis | 46.13 | 12.00 | 45 | 29283 | 14963 | 63444731 |
Treatment failure | 44.68 | 12.00 | 18 | 29310 | 199025 | 63260669 |
Constipation | 44.00 | 12.00 | 213 | 29115 | 224730 | 63234964 |
Gastric ulcer | 40.97 | 12.00 | 53 | 29275 | 23984 | 63435710 |
Exposure during pregnancy | 40.27 | 12.00 | 11 | 29317 | 155536 | 63304158 |
Early satiety | 37.73 | 12.00 | 15 | 29313 | 981 | 63458713 |
Rectal haemorrhage | 37.50 | 12.00 | 75 | 29253 | 48955 | 63410739 |
Facial asymmetry | 37.17 | 12.00 | 14 | 29314 | 791 | 63458903 |
Muscle swelling | 35.97 | 12.00 | 12 | 29316 | 474 | 63459220 |
Impaired gastric emptying | 35.60 | 12.00 | 33 | 29295 | 10299 | 63449395 |
Product use issue | 34.07 | 12.00 | 31 | 29297 | 220489 | 63239205 |
Gastrooesophageal reflux disease | 33.69 | 12.00 | 109 | 29219 | 95530 | 63364164 |
Rheumatoid arthritis | 33.27 | 12.00 | 41 | 29287 | 253778 | 63205916 |
Wound | 33.15 | 12.00 | 17 | 29311 | 163246 | 63296448 |
Abdominal pain upper | 33.09 | 12.00 | 185 | 29143 | 206259 | 63253435 |
Lower respiratory tract infection | 33.06 | 12.00 | 10 | 29318 | 132297 | 63327397 |
Dehydration | 33.05 | 12.00 | 163 | 29165 | 173191 | 63286503 |
Haematochezia | 32.98 | 12.00 | 75 | 29253 | 53469 | 63406225 |
Drug intolerance | 32.54 | 12.00 | 58 | 29270 | 308603 | 63151091 |
Weight decreased | 32.49 | 12.00 | 229 | 29099 | 276569 | 63183125 |
Musculoskeletal stiffness | 32.21 | 12.00 | 23 | 29305 | 184595 | 63275099 |
Hepatic enzyme increased | 30.60 | 12.00 | 29 | 29299 | 202299 | 63257395 |
Vulval disorder | 29.14 | 12.00 | 12 | 29316 | 860 | 63458834 |
General physical health deterioration | 28.03 | 12.00 | 31 | 29297 | 201371 | 63258323 |
Cholelithiasis | 27.57 | 12.00 | 62 | 29266 | 43863 | 63415831 |
Gastrointestinal haemorrhage | 27.23 | 12.00 | 91 | 29237 | 81085 | 63378609 |
Product dose omission issue | 26.98 | 12.00 | 193 | 29135 | 234120 | 63225574 |
Completed suicide | 26.95 | 12.00 | 17 | 29311 | 145656 | 63314038 |
Tarsal tunnel syndrome | 26.57 | 12.00 | 10 | 29318 | 564 | 63459130 |
Therapeutic product effect decreased | 24.48 | 12.00 | 32 | 29296 | 193155 | 63266539 |
Urinary tract infection | 24.38 | 12.00 | 207 | 29121 | 264477 | 63195217 |
Alopecia | 24.00 | 12.00 | 78 | 29250 | 337458 | 63122236 |
Intentional overdose | 23.97 | 12.00 | 3 | 29325 | 74149 | 63385545 |
Arthropathy | 23.94 | 12.00 | 45 | 29283 | 234747 | 63224947 |
Gallbladder disorder | 23.83 | 12.00 | 36 | 29292 | 18806 | 63440888 |
Helicobacter infection | 23.20 | 12.00 | 7 | 29321 | 92778 | 63366916 |
Discomfort | 23.03 | 12.00 | 26 | 29302 | 167348 | 63292346 |
Anaemia | 22.71 | 12.00 | 221 | 29107 | 293209 | 63166485 |
Haematemesis | 22.63 | 12.00 | 46 | 29282 | 30366 | 63429328 |
Diarrhoea | 22.56 | 12.00 | 459 | 28869 | 714907 | 62744787 |
Paranoia | 21.88 | 12.00 | 27 | 29301 | 11652 | 63448042 |
Genotype drug resistance test positive | 21.71 | 12.00 | 8 | 29320 | 425 | 63459269 |
Cellulitis | 21.64 | 12.00 | 85 | 29243 | 81873 | 63377821 |
Vascular rupture | 21.51 | 12.00 | 12 | 29316 | 1688 | 63458006 |
Haemoglobin decreased | 21.09 | 12.00 | 127 | 29201 | 145358 | 63314336 |
Oesophageal stenosis | 20.96 | 12.00 | 15 | 29313 | 3251 | 63456443 |
External ear cellulitis | 20.83 | 12.00 | 7 | 29321 | 283 | 63459411 |
Blister | 20.34 | 12.00 | 18 | 29310 | 129796 | 63329898 |
Movement disorder | 20.11 | 12.00 | 36 | 29292 | 21625 | 63438069 |
Purpura senile | 19.67 | 12.00 | 8 | 29320 | 555 | 63459139 |
Vomiting | 19.62 | 12.00 | 365 | 28963 | 559252 | 62900442 |
Drug abuse | 19.00 | 12.00 | 5 | 29323 | 72513 | 63387181 |
Faeces discoloured | 18.79 | 12.00 | 32 | 29296 | 18477 | 63441217 |
Off label use | 18.50 | 12.00 | 211 | 29117 | 674251 | 62785443 |
Chronic sinusitis | 18.36 | 12.00 | 26 | 29302 | 12817 | 63446877 |
Liver abscess | 18.07 | 12.00 | 13 | 29315 | 2841 | 63456853 |
Procedural pain | 17.71 | 12.00 | 34 | 29294 | 21535 | 63438159 |
Blood alkaline phosphatase increased | 16.99 | 12.00 | 51 | 29277 | 42916 | 63416778 |
Hallucination, auditory | 16.93 | 12.00 | 25 | 29303 | 12799 | 63446895 |
Migraine | 16.79 | 12.00 | 93 | 29235 | 103253 | 63356441 |
Peptic ulcer | 16.48 | 12.00 | 15 | 29313 | 4572 | 63455122 |
Blood magnesium decreased | 16.38 | 12.00 | 25 | 29303 | 13173 | 63446521 |
Biliary dyskinesia | 16.30 | 12.00 | 12 | 29316 | 2717 | 63456977 |
Pancreatic enzyme abnormality | 15.89 | 12.00 | 3 | 29325 | 9 | 63459685 |
Pancreatitis | 15.57 | 12.00 | 54 | 29274 | 49001 | 63410693 |
Upper respiratory tract infection | 15.51 | 12.00 | 77 | 29251 | 81970 | 63377724 |
Hiatus hernia | 15.28 | 12.00 | 32 | 29296 | 21562 | 63438132 |
Gallbladder injury | 15.21 | 12.00 | 9 | 29319 | 1414 | 63458280 |
Vestibular disorder | 15.16 | 12.00 | 9 | 29319 | 1422 | 63458272 |
Swelling | 14.86 | 12.00 | 71 | 29257 | 275307 | 63184387 |
Dyspepsia | 14.67 | 12.00 | 89 | 29239 | 102107 | 63357587 |
Dysphagia | 14.58 | 12.00 | 80 | 29248 | 88505 | 63371189 |
Flatulence | 14.50 | 12.00 | 42 | 29286 | 34660 | 63425034 |
Rash | 14.01 | 12.00 | 179 | 29149 | 560692 | 62899002 |
Gastric haemorrhage | 13.98 | 12.00 | 16 | 29312 | 6382 | 63453312 |
Psoriatic arthropathy | 13.96 | 12.00 | 13 | 29315 | 91507 | 63368187 |
Blood pressure diastolic increased | 13.92 | 12.00 | 20 | 29308 | 9990 | 63449704 |
Resorption bone increased | 13.47 | 12.00 | 8 | 29320 | 1266 | 63458428 |
Suture insertion | 13.35 | 12.00 | 5 | 29323 | 278 | 63459416 |
Hypersensitivity | 13.28 | 12.00 | 80 | 29248 | 292605 | 63167089 |
Impaired healing | 12.96 | 12.00 | 17 | 29311 | 102525 | 63357169 |
Oesophageal ulcer | 12.94 | 12.00 | 13 | 29315 | 4477 | 63455217 |
Obstruction | 12.78 | 12.00 | 11 | 29317 | 3116 | 63456578 |
Ocular neoplasm | 12.71 | 12.00 | 5 | 29323 | 318 | 63459376 |
Overdose | 12.67 | 12.00 | 21 | 29307 | 115057 | 63344637 |
Limb mass | 12.46 | 12.00 | 11 | 29317 | 3221 | 63456473 |
Burning sensation | 12.45 | 12.00 | 54 | 29274 | 54353 | 63405341 |
Drug interaction | 12.40 | 12.00 | 59 | 29269 | 229072 | 63230622 |
Thiopurine methyltransferase decreased | 12.36 | 12.00 | 5 | 29323 | 342 | 63459352 |
Depression | 12.36 | 12.00 | 142 | 29186 | 196350 | 63263344 |
Lip ulceration | 12.21 | 12.00 | 9 | 29319 | 2041 | 63457653 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Gastrointestinal haemorrhage | 47.04 | 11.95 | 106 | 13645 | 88371 | 34854809 |
Blood aluminium increased | 38.62 | 11.95 | 6 | 13745 | 3 | 34943177 |
Gastrooesophageal reflux disease | 34.39 | 11.95 | 57 | 13694 | 37867 | 34905313 |
Oesophagitis | 31.29 | 11.95 | 32 | 13719 | 13229 | 34929951 |
Asthma-chronic obstructive pulmonary disease overlap syndrome | 23.38 | 11.95 | 11 | 13740 | 1276 | 34941904 |
Dysphagia | 22.92 | 11.95 | 65 | 13686 | 62316 | 34880864 |
Brugada syndrome | 21.49 | 11.95 | 9 | 13742 | 792 | 34942388 |
Completed suicide | 21.48 | 11.95 | 6 | 13745 | 98162 | 34845018 |
Vomiting | 20.61 | 11.95 | 167 | 13584 | 247454 | 34695726 |
Gastric mucosal calcinosis | 20.52 | 11.95 | 3 | 13748 | 0 | 34943180 |
Nausea | 19.19 | 11.95 | 211 | 13540 | 339697 | 34603483 |
Toxicity to various agents | 18.97 | 11.95 | 31 | 13720 | 200331 | 34742849 |
Blood immunoglobulin E increased | 18.81 | 11.95 | 12 | 13739 | 2534 | 34940646 |
Decreased appetite | 18.30 | 11.95 | 120 | 13631 | 166272 | 34776908 |
Oesophageal ulcer | 17.97 | 11.95 | 13 | 13738 | 3368 | 34939812 |
Mucosal erosion | 17.79 | 11.95 | 8 | 13743 | 836 | 34942344 |
Hypogonadism | 17.59 | 11.95 | 11 | 13740 | 2244 | 34940936 |
Pneumonia | 17.32 | 11.95 | 218 | 13533 | 362409 | 34580771 |
Off label use | 17.19 | 11.95 | 96 | 13655 | 419428 | 34523752 |
Sputum increased | 17.08 | 11.95 | 11 | 13740 | 2359 | 34940821 |
COVID-19 treatment | 14.22 | 11.95 | 5 | 13746 | 273 | 34942907 |
Dehydration | 13.83 | 11.95 | 93 | 13658 | 129876 | 34813304 |
Fatigue | 13.70 | 11.95 | 213 | 13538 | 370440 | 34572740 |
Ulcer haemorrhage | 13.59 | 11.95 | 10 | 13741 | 2660 | 34940520 |
Product use in unapproved indication | 13.28 | 11.95 | 16 | 13735 | 117483 | 34825697 |
Dyspepsia | 13.21 | 11.95 | 38 | 13713 | 36694 | 34906486 |
Gastrointestinal pain | 13.13 | 11.95 | 11 | 13740 | 3531 | 34939649 |
Enterococcus test positive | 13.11 | 11.95 | 7 | 13744 | 1062 | 34942118 |
Muscle twitching | 12.90 | 11.95 | 18 | 13733 | 10280 | 34932900 |
Drug abuse | 12.87 | 11.95 | 12 | 13739 | 99084 | 34844096 |
Joint dislocation reduction | 12.42 | 11.95 | 3 | 13748 | 42 | 34943138 |
Drug ineffective | 12.20 | 11.95 | 118 | 13633 | 456633 | 34486547 |
Adenocarcinoma gastric | 12.17 | 11.95 | 7 | 13744 | 1226 | 34941954 |
Abdominal pain upper | 12.14 | 11.95 | 58 | 13693 | 71432 | 34871748 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Toxicity to various agents | 61.70 | 11.18 | 52 | 33474 | 421488 | 79289374 |
Oesophagitis | 58.28 | 11.18 | 61 | 33465 | 24228 | 79686634 |
Gastrointestinal haemorrhage | 57.51 | 11.18 | 164 | 33362 | 147555 | 79563307 |
Cholecystitis chronic | 54.67 | 11.18 | 40 | 33486 | 9866 | 79700996 |
Nausea | 52.44 | 11.18 | 623 | 32903 | 956573 | 78754289 |
Gastritis | 50.43 | 11.18 | 80 | 33446 | 47913 | 79662949 |
Completed suicide | 48.97 | 11.18 | 21 | 33505 | 245746 | 79465116 |
Gastrooesophageal reflux disease | 48.89 | 11.18 | 124 | 33402 | 104122 | 79606740 |
Abdominal pain | 47.48 | 11.18 | 303 | 33223 | 389266 | 79321596 |
Vaginal flatulence | 45.35 | 11.18 | 22 | 33504 | 2553 | 79708309 |
Drug ineffective | 44.91 | 11.18 | 269 | 33257 | 1080644 | 78630218 |
Blood aluminium increased | 43.09 | 11.18 | 7 | 33519 | 6 | 79710856 |
Proctitis | 42.52 | 11.18 | 29 | 33497 | 6403 | 79704459 |
Contraindicated product administered | 41.37 | 11.18 | 8 | 33518 | 157530 | 79553332 |
Female genital tract fistula | 39.64 | 11.18 | 27 | 33499 | 5948 | 79704914 |
Impaired gastric emptying | 38.21 | 11.18 | 33 | 33493 | 10320 | 79700542 |
Maternal exposure during pregnancy | 37.89 | 11.18 | 6 | 33520 | 136532 | 79574330 |
Angina bullosa haemorrhagica | 36.88 | 11.18 | 10 | 33516 | 211 | 79710651 |
Drug abuse | 33.86 | 11.18 | 13 | 33513 | 162678 | 79548184 |
Early satiety | 33.77 | 11.18 | 15 | 33511 | 1424 | 79709438 |
Vomiting | 33.56 | 11.18 | 427 | 33099 | 665401 | 79045461 |
Pericarditis | 32.80 | 11.18 | 3 | 33523 | 104233 | 79606629 |
Hand deformity | 32.68 | 11.18 | 3 | 33523 | 103916 | 79606946 |
Abdominal pain upper | 32.27 | 11.18 | 182 | 33344 | 223637 | 79487225 |
Vaginal discharge | 32.13 | 11.18 | 26 | 33500 | 7437 | 79703425 |
Joint swelling | 31.80 | 11.18 | 45 | 33481 | 288601 | 79422261 |
Facial asymmetry | 30.86 | 11.18 | 12 | 33514 | 814 | 79710048 |
Off label use | 30.54 | 11.18 | 240 | 33286 | 906975 | 78803887 |
Haemoglobin decreased | 29.03 | 11.18 | 176 | 33350 | 221943 | 79488919 |
Constipation | 28.40 | 11.18 | 210 | 33316 | 282840 | 79428022 |
Radiculopathy | 28.34 | 11.18 | 26 | 33500 | 8798 | 79702064 |
Overdose | 27.80 | 11.18 | 22 | 33504 | 184184 | 79526678 |
Dehydration | 27.14 | 11.18 | 188 | 33338 | 247999 | 79462863 |
Gastric ulcer | 27.02 | 11.18 | 50 | 33476 | 33855 | 79677007 |
Vulval disorder | 26.77 | 11.18 | 10 | 33516 | 608 | 79710254 |
Dysphagia | 26.75 | 11.18 | 112 | 33414 | 122024 | 79588838 |
Systemic lupus erythematosus | 26.36 | 11.18 | 9 | 33517 | 121140 | 79589722 |
Colitis | 25.28 | 11.18 | 78 | 33448 | 73229 | 79637633 |
Oesophageal ulcer | 25.27 | 11.18 | 22 | 33504 | 6953 | 79703909 |
Oesophageal stenosis | 24.98 | 11.18 | 18 | 33508 | 4336 | 79706526 |
Drug intolerance | 24.57 | 11.18 | 46 | 33480 | 264073 | 79446789 |
Frequent bowel movements | 24.09 | 11.18 | 44 | 33482 | 29495 | 79681367 |
Cholelithiasis | 24.01 | 11.18 | 62 | 33464 | 52602 | 79658260 |
Weight decreased | 23.81 | 11.18 | 241 | 33285 | 354957 | 79355905 |
Muscle swelling | 23.73 | 11.18 | 10 | 33516 | 835 | 79710027 |
Procedural pain | 23.59 | 11.18 | 38 | 33488 | 23046 | 79687816 |
Haematemesis | 23.28 | 11.18 | 61 | 33465 | 52203 | 79658659 |
Exposure during pregnancy | 22.91 | 11.18 | 7 | 33519 | 101125 | 79609737 |
Intentional overdose | 22.83 | 11.18 | 8 | 33518 | 105952 | 79604910 |
Oral candidiasis | 22.75 | 11.18 | 43 | 33483 | 29585 | 79681277 |
Ulcer haemorrhage | 22.34 | 11.18 | 19 | 33507 | 5819 | 79705043 |
Dyspepsia | 21.75 | 11.18 | 97 | 33429 | 108590 | 79602272 |
Treatment failure | 21.45 | 11.18 | 24 | 33502 | 170462 | 79540400 |
Macular degeneration | 21.28 | 11.18 | 25 | 33501 | 11271 | 79699591 |
Purpura senile | 20.87 | 11.18 | 8 | 33518 | 522 | 79710340 |
Tarsal tunnel syndrome | 20.78 | 11.18 | 8 | 33518 | 528 | 79710334 |
Product dose omission issue | 20.10 | 11.18 | 175 | 33351 | 247362 | 79463500 |
Lower respiratory tract infection | 20.05 | 11.18 | 15 | 33511 | 129205 | 79581657 |
Product use issue | 19.99 | 11.18 | 36 | 33490 | 209786 | 79501076 |
General physical health deterioration | 19.86 | 11.18 | 55 | 33471 | 275183 | 79435679 |
Diarrhoea | 19.54 | 11.18 | 496 | 33030 | 879993 | 78830869 |
Hypogonadism | 19.43 | 11.18 | 11 | 33515 | 1749 | 79709113 |
Gastrointestinal pain | 18.88 | 11.18 | 22 | 33504 | 9833 | 79701029 |
Glossodynia | 18.77 | 11.18 | 10 | 33516 | 103327 | 79607535 |
Gallbladder disorder | 18.63 | 11.18 | 31 | 33495 | 19309 | 79691553 |
Blood alkaline phosphatase increased | 18.58 | 11.18 | 64 | 33462 | 63600 | 79647262 |
Musculoskeletal stiffness | 18.56 | 11.18 | 28 | 33498 | 174980 | 79535882 |
Psoriatic arthropathy | 18.40 | 11.18 | 5 | 33521 | 77994 | 79632868 |
Biliary dyskinesia | 18.08 | 11.18 | 12 | 33514 | 2533 | 79708329 |
External ear cellulitis | 17.69 | 11.18 | 6 | 33520 | 275 | 79710587 |
Vascular rupture | 17.18 | 11.18 | 10 | 33516 | 1675 | 79709187 |
Brugada syndrome | 17.17 | 11.18 | 9 | 33517 | 1229 | 79709633 |
Rheumatoid arthritis | 17.10 | 11.18 | 39 | 33487 | 208431 | 79502431 |
Chronic sinusitis | 16.94 | 11.18 | 24 | 33502 | 13002 | 79697860 |
Hiatus hernia | 16.87 | 11.18 | 33 | 33493 | 23279 | 79687583 |
Hepatic enzyme increased | 16.80 | 11.18 | 32 | 33494 | 182578 | 79528284 |
Paranoia | 15.92 | 11.18 | 29 | 33497 | 19403 | 79691459 |
Therapeutic product effect decreased | 15.71 | 11.18 | 28 | 33498 | 163835 | 79547027 |
Gastric haemorrhage | 15.68 | 11.18 | 25 | 33501 | 15025 | 79695837 |
Helicobacter infection | 15.47 | 11.18 | 5 | 33521 | 69699 | 79641163 |
Product use in unapproved indication | 15.26 | 11.18 | 54 | 33472 | 250305 | 79460557 |
Blood potassium decreased | 14.67 | 11.18 | 48 | 33478 | 46464 | 79664398 |
Cellulitis | 14.60 | 11.18 | 87 | 33439 | 108973 | 79601889 |
Pneumonia | 14.34 | 11.18 | 371 | 33155 | 659875 | 79050987 |
Urinary tract infection | 14.16 | 11.18 | 177 | 33349 | 274335 | 79436527 |
Folliculitis | 14.14 | 11.18 | 3 | 33523 | 55377 | 79655485 |
Genotype drug resistance test positive | 13.97 | 11.18 | 8 | 33518 | 1300 | 79709562 |
Short-bowel syndrome | 13.57 | 11.18 | 6 | 33520 | 563 | 79710299 |
Lymphocytosis | 13.49 | 11.18 | 13 | 33513 | 4680 | 79706182 |
Asthma-chronic obstructive pulmonary disease overlap syndrome | 13.40 | 11.18 | 11 | 33515 | 3210 | 79707652 |
Movement disorder | 13.37 | 11.18 | 33 | 33493 | 27226 | 79683636 |
Resorption bone increased | 13.08 | 11.18 | 8 | 33518 | 1467 | 79709395 |
Upper respiratory tract infection | 13.03 | 11.18 | 74 | 33452 | 91094 | 79619768 |
Ocular neoplasm | 12.99 | 11.18 | 5 | 33521 | 330 | 79710532 |
Faeces discoloured | 12.97 | 11.18 | 34 | 33492 | 29093 | 79681769 |
Colitis ulcerative | 12.95 | 11.18 | 38 | 33488 | 34704 | 79676158 |
Drug interaction | 12.91 | 11.18 | 112 | 33414 | 415071 | 79295791 |
Suture insertion | 12.87 | 11.18 | 5 | 33521 | 338 | 79710524 |
Melaena | 12.67 | 11.18 | 55 | 33471 | 60835 | 79650027 |
Thiopurine methyltransferase decreased | 12.56 | 11.18 | 5 | 33521 | 361 | 79710501 |
Lactic acidosis | 12.50 | 11.18 | 7 | 33519 | 70352 | 79640510 |
Limb mass | 12.34 | 11.18 | 11 | 33515 | 3588 | 79707274 |
Gastric ulcer haemorrhage | 12.29 | 11.18 | 17 | 33509 | 9010 | 79701852 |
Skin infection | 12.21 | 11.18 | 25 | 33501 | 18220 | 79692642 |
Anaemia | 12.08 | 11.18 | 258 | 33268 | 444757 | 79266105 |
Hypersensitivity | 12.03 | 11.18 | 63 | 33463 | 262176 | 79448686 |
Wound | 11.92 | 11.18 | 19 | 33507 | 116160 | 79594702 |
Upper gastrointestinal haemorrhage | 11.55 | 11.18 | 41 | 33485 | 41339 | 79669523 |
Vestibular disorder | 11.52 | 11.18 | 9 | 33517 | 2446 | 79708416 |
Gastroenteritis | 11.50 | 11.18 | 36 | 33490 | 34046 | 79676816 |
Gastrointestinal ulcer haemorrhage | 11.43 | 11.18 | 7 | 33519 | 1286 | 79709576 |
COVID-19 treatment | 11.35 | 11.18 | 5 | 33521 | 465 | 79710397 |
Blood loss anaemia | 11.29 | 11.18 | 22 | 33504 | 15476 | 79695386 |
Gastric disorder | 11.24 | 11.18 | 38 | 33488 | 37395 | 79673467 |
None
Source | Code | Description |
---|---|---|
ATC | A02BX02 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR ACID RELATED DISORDERS DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD) |
FDA CS | M0015420 | Organometallic Compounds |
MeSH PA | D000897 | Anti-Ulcer Agents |
MeSH PA | D005765 | Gastrointestinal Agents |
FDA EPC | N0000175801 | Aluminum Complex |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Duodenal ulcer disease | indication | 51868009 | DOID:1724 |
Maintenance of Healing Duodenal Ulcer | indication | ||
Gingivostomatitis | off-label use | 20607006 | |
Peptic reflux disease | off-label use | 57643001 | |
Stomatitis | off-label use | 61170000 | DOID:9637 |
Gastroesophageal reflux disease | off-label use | 235595009 | DOID:8534 |
Gastric ulcer | off-label use | 397825006 | DOID:10808 |
NSAID-Induced Duodenal Ulcer | off-label use | ||
Sclerotherapy Induced Esophageal Ulcer | off-label use | ||
Stress-Related GI Mucosal Bleeding Prevention | off-label use | ||
Maintenance of Healing Gastric Ulcer | off-label use | ||
Prevention of Stress Ulcer | off-label use | ||
Sclerotherapy-Induced Mucositis | off-label use | ||
End stage renal disease | contraindication | 46177005 | DOID:784 |
Hyperglycemia | contraindication | 80394007 | DOID:4195 |
Aluminum intoxication | contraindication | 236546003 |
None
None
None
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Pepsin A-5 | Enzyme | INHIBITOR | CHEMBL | CHEMBL |
ID | Source |
---|---|
4018816 | VUID |
N0000147119 | NUI |
4018816 | VANDF |
C0038633 | UMLSCUI |
CHEBI:9313 | CHEBI |
CHEMBL3989780 | ChEMBL_ID |
CHEMBL2367706 | ChEMBL_ID |
D013392 | MESH_DESCRIPTOR_UI |
DB00364 | DRUGBANK_ID |
7055 | IUPHAR_LIGAND_ID |
2723 | INN_ID |
XX73205DH5 | UNII |
10156 | RXNORM |
1948 | MMSL |
476 | MMSL |
5518 | MMSL |
d00377 | MMSL |
001132 | NDDF |
387387008 | SNOMEDCT_US |
69967001 | SNOMEDCT_US |
121494085 | PUBCHEM_CID |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-2210 | TABLET | 1 g | ORAL | ANDA | 20 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-2210 | TABLET | 1 g | ORAL | ANDA | 20 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0121-0747 | SUSPENSION | 1 g | ORAL | NDA | 20 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0121-0974 | SUSPENSION | 1 g | ORAL | ANDA | 17 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0121-0974 | SUSPENSION | 1 g | ORAL | ANDA | 17 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0254-1011 | SUSPENSION | 1 g | ORAL | NDA authorized generic | 19 sections |
sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-9205 | SUSPENSION | 1 g | ORAL | ANDA | 20 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-4517 | TABLET | 1 g | ORAL | ANDA | 20 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-7269 | SUSPENSION | 1 g | ORAL | ANDA | 17 sections |
SUCRALFATE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16590-523 | TABLET | 1 g | ORAL | ANDA | 2 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 17856-0062 | SUSPENSION | 1 g | ORAL | ANDA | 18 sections |
Carafate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 17856-0170 | SUSPENSION | 1 g | ORAL | NDA | 19 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 17856-0306 | SUSPENSION | 1 g | ORAL | ANDA | 17 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 17856-1011 | SUSPENSION | 1 g | ORAL | NDA AUTHORIZED GENERIC | 19 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 17856-1011 | SUSPENSION | 1 g | ORAL | NDA AUTHORIZED GENERIC | 19 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 29033-003 | TABLET | 1 g | ORAL | ANDA | 18 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42291-757 | TABLET | 1 g | ORAL | ANDA | 20 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42291-781 | SUSPENSION | 1 g | ORAL | ANDA | 18 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42291-781 | SUSPENSION | 1 g | ORAL | ANDA | 18 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 43353-061 | TABLET | 1 g | ORAL | NDA | 18 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-0582 | TABLET | 1 g | ORAL | ANDA | 20 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-3019 | TABLET | 1 g | ORAL | ANDA | 20 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-5287 | TABLET | 1 g | ORAL | NDA AUTHORIZED GENERIC | 18 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-5287 | TABLET | 1 g | ORAL | NDA AUTHORIZED GENERIC | 18 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-6455 | TABLET | 1 g | ORAL | ANDA | 18 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50268-732 | SUSPENSION | 1 g | ORAL | ANDA | 18 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50268-745 | SUSPENSION | 1 g | ORAL | ANDA | 18 sections |
Sucralfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51079-753 | TABLET | 1 g | ORAL | ANDA | 20 sections |
SUCRALFATE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51655-031 | TABLET | 1 g | ORAL | ANDA | 20 sections |
SUCRALFATE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51655-031 | TABLET | 1 g | ORAL | ANDA | 20 sections |