bismuth subnitrate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
4841 1304-85-4

Description:

MoleculeDescription

Synonyms:

  • bismuth subnitrate
antacid containing bismuth, sodium & magnesium carbonates, rutin, Khellin & Rhamnus bark powder; do not confuse with colloidal bismuth subcitrate
  • Molecular weight: 1461.98
  • Formula: Bi5H9N4O22
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 92.83
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Myasthenia gravis 184.11 145.12 65 3768 16072 42601430
Hyperphosphataemia 150.65 145.12 53 3780 12951 42604551

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Myasthenia gravis 225.10 107.46 65 3864 21446 110563924
Hyperphosphataemia 187.05 107.46 53 3876 16328 110569042
Analgesic therapy 157.05 107.46 39 3890 7245 110578125
Activated partial thromboplastin time prolonged 154.05 107.46 49 3880 22319 110563051
Appendicolith 153.19 107.46 44 3885 14211 110571159
Drug therapy 152.00 107.46 38 3891 7253 110578117
Hypophosphataemia 150.23 107.46 53 3876 33129 110552241
Congenital hiatus hernia 147.52 107.46 36 3893 6223 110579147
Sleep disorder therapy 146.12 107.46 37 3892 7434 110577936
Anticoagulant therapy 142.61 107.46 34 3895 5327 110580043
Antacid therapy 141.85 107.46 34 3895 5450 110579920
Neuralgia 134.12 107.46 54 3875 48424 110536946
Blood phosphorus increased 130.09 107.46 40 3889 16300 110569070
Incorrect route of product administration 129.24 107.46 57 3872 64004 110521366
Appendicitis 127.05 107.46 45 3884 28419 110556951
Bacterial infection 126.38 107.46 51 3878 45985 110539385
End stage renal disease 123.32 107.46 41 3888 21432 110563938
Blood uric acid increased 123.22 107.46 41 3888 21488 110563882
Stress 116.23 107.46 62 3867 105286 110480084
Bronchopulmonary aspergillosis allergic 113.26 107.46 31 3898 8395 110576975
Ventricular fibrillation 110.74 107.46 45 3884 41268 110544102
Blood calcium increased 109.82 107.46 36 3893 18004 110567366
Gout 109.00 107.46 43 3886 36523 110548847

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A02BX12 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR ACID RELATED DISORDERS
DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD)
MeSH PA D000863 Antacids
MeSH PA D005765 Gastrointestinal Agents
CHEBI has role CHEBI:49201 anti-ulcer drug

Related Drugs by ATC class:

A02BX Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD) 15 drugs
acetoxolonealginic acidbismuth subcitratecarbenoxolonegefarnateirsogladinemethiosulfonium chloridepirenzepineproglumiderebamipidesucralfatesulglicotide show all 15 →

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
H19J064BA5 UNII
D01642 KEGG_DRUG
4018999 VUID
N0000147275 NUI
4018999 VANDF
C0053791 UMLSCUI
CHEBI:31293 CHEBI
CHEMBL3833348 ChEMBL_ID
73415757 PUBCHEM_CID
DB13209 DRUGBANK_ID
C010804 MESH_SUPPLEMENTAL_RECORD_UI
19477 RXNORM
4289 MMSL
4882 MMSL
d03594 MMSL
001913 NDDF
004332 NDDF
391852006 SNOMEDCT_US
421038002 SNOMEDCT_US

Pharmaceutical products:

None