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irsogladine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 1484 | 57381-26-7 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
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Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,AURKA,AXL,BRAF,CAMK2B,CAMK2D,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,ERBB2,FLT3,GRK2,ITK,JAK1,MAP3K21,MAPK7,MET,MTOR,NTRK2,PDK1,PDK2,PIK3CA,PIK3CB,PIK3CD,PIK3CG,PRKCD,PRKDC,SIK2,SIK3,STK33,TEK,TTK | 35 | |||
| kinase-selectivity-class | AXL,BRAF,DYRK1B,GRK2,IKBKB,MAP2K3,MAP3K21,MAPK7,TTK | 9 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | A02BX16 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR ACID RELATED DISORDERS DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD) |
| MeSH PA | D000897 | Anti-Ulcer Agents |
| MeSH PA | D000970 | Antineoplastic Agents |
| MeSH PA | D005765 | Gastrointestinal Agents |
| MeSH PA | D011837 | Radiation-Protective Agents |
| MeSH PA | D016588 | Anticarcinogenic Agents |
| MeSH PA | D020011 | Protective Agents |
| CHEBI has role | CHEBI:49201 | anti-ulcer drug |
Related Drugs by ATC class:
A02BX Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD) 15 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 4.25 | Basic |
| pKa2 | 1.04 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D01658 | KEGG_DRUG |
| C0063879 | UMLSCUI |
| CHEBI:93307 | CHEBI |
| CHEMBL136497 | ChEMBL_ID |
| DB13056 | DRUGBANK_ID |
| CHEMBL1712923 | ChEMBL_ID |
| C041836 | MESH_SUPPLEMENTAL_RECORD_UI |
| 3752 | PUBCHEM_CID |
| 6223 | INN_ID |
| 84504-69-8 | SECONDARY_CAS_RN |
| QBX79NZC1D | UNII |
Pharmaceutical products:
None