methiosulfonium chloride 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
3354 1115-84-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • s-methylmethionine
  • methyl sulfonium methionine
  • S-Methyl-L-methionine
  • S-Methylmethionine sulfonium salt
  • methiosulfonium chloride
  • Molecular weight: 164.24
  • Formula: C6H14NO2S
  • CLOGP: -1.71
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 2
  • TPSA: 63.32
  • ALOGS: -1.39
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AURKA,AXL,BRAF,BTK,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,GRK2,GSK3B,ITK,JAK2,JAK3,KDR,MAP2K6,MAP3K21,MAP3K7,MAPK10,MAPK7,MAPKAPK2,NTRK1,NTRK2,PDK1,PDK2,PDK4,PIK3CB,PIM2,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,ZAP70 43
kinase-selectivity-class AXL,BRAF,CDK4,CDK9,EIF2AK3,EPHB4,GRK2,MAP2K6,STK33,TEK,TGFBR1,ZAP70 12
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A02BX04 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR ACID RELATED DISORDERS
DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD)
CHEBI has role CHEBI:75772 <em>Saccharomyces cerevisiae </em> metabolite
CHEBI has role CHEBI:76971 <em>Escherichia coli</em> metabolite

Related Drugs by ATC class:

A02BX Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD) 15 drugs
acetoxolonealginic acidbismuth subcitratebismuth subnitratecarbenoxolonegefarnateirsogladinepirenzepineproglumiderebamipidesucralfatesulglicotide show all 15 →

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.49 acidic
pKa2 9.93 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
CHEBI:6884 CHEBI
CHEMBL1797128 ChEMBL_ID
DB13250 DRUGBANK_ID
713357001 SNOMEDCT_US
C0658922 UMLSCUI
16217806 PUBCHEM_CID
3485Y39925 UNII
7O2D9U053L UNII
G9CUR2204U UNII
I798Y91P58 UNII

Pharmaceutical products:

None