fenoxazoline 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antihistaminics or local vasoconstrictors, antazoline derivatives 3225 4846-91-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • fenoxazoline
  • nebulicina
  • phenoxazoline
  • Molecular weight: 218.30
  • Formula: C13H18N2O
  • CLOGP: 3.03
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 1
  • TPSA: 33.62
  • ALOGS: -2.84
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC R01AA12 RESPIRATORY SYSTEM
NASAL PREPARATIONS
DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
Sympathomimetics, plain

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.49 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Nischarin Membrane receptor Ki 8.70 CHEMBL

External reference:

IDSource
D07372 KEGG_DRUG
C0060183 UMLSCUI
CHEBI:134903 CHEBI
CHEMBL14012 ChEMBL_ID
DB13736 DRUGBANK_ID
71899 PUBCHEM_CID
C040400 MESH_SUPPLEMENTAL_RECORD_UI
1217 INN_ID
97JJW1W1R3 UNII
24856 RXNORM
005806 NDDF

Pharmaceutical products:

None