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| Stem definition | Drug id | CAS RN |
|---|---|---|
| 2779 | 30751-05-4 |
| Molecule | Description |
|---|---|
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Synonyms:
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| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,AKT2,AKT3,ALK,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK1,CDK4,CDK5,CDK9,CHEK1,CSF1R,DDR1,DYRK1B,EGFR,EIF2AK3,EPHA2,EPHB4,ERBB2,FLT3,GRK2,GSK3B,IRAK1,ITK,JAK1,JAK2,JAK3,MAP2K6,MAP3K1,MAP3K10,MAP3K21,MAP3K7,MAP4K1,MAP4K3,MAPK7,MAPK9,MARK4,MELK,MET,MTOR,NTRK1,NTRK2,PAK4,PDK2,PDK4,PDPK1,PIK3CB,PIM2,PRKCD,PRKDC,SGK1,SIK2,SIK3,STK33,SYK,TEK,TTK,ULK1,ULK2 | 64 | |||
| kinase-selectivity-class | AKT3,ALK,AXL,BRAF,CAMK2D,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,GRK2,IRAK3,JAK1,MAP3K21,MAP4K1,MAPK7,MARK4,PDK4,PIK3CB,PRKCD,SIK2,SIK3,STK33,TTK,ULK1,ULK2 | 27 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
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| Source | Code | Description |
|---|---|---|
| ATC | A02BX11 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR ACID RELATED DISORDERS DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD) |
| CHEBI has role | CHEBI:49201 | anti-ulcer drug |
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Gastric ulcer | indication | 397825006 | DOID:10808 |
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| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 13.05 | acidic |
| pKa2 | 8.18 | Basic |
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| ID | Source |
|---|---|
| D01306 | KEGG_DRUG |
| C0147037 | UMLSCUI |
| CHEBI:32271 | CHEBI |
| CHEMBL1566956 | ChEMBL_ID |
| DB13419 | DRUGBANK_ID |
| C028936 | MESH_SUPPLEMENTAL_RECORD_UI |
| 5597 | PUBCHEM_CID |
| 5461 | INN_ID |
| W6QJX1Q00Z | UNII |
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