Stem definition | Drug id | CAS RN |
---|---|---|
269 | 446-86-6 |
Dose | Unit | Route |
---|---|---|
0.15 | g | O |
0.15 | g | P |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 1 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 10 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 1 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 18.03 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 60 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Date | Agency | Company | Orphan |
---|---|---|---|
March 20, 1968 | FDA | PROMETHEUS LABS | |
Feb. 21, 2019 | PMDA | ASPEN JAPAN K.K.; MITSUBISHI TANABE PHARMA CORPORATION |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Off label use | 561.85 | 9.62 | 2357 | 113539 | 472069 | 50017159 |
Drug ineffective | 536.53 | 9.62 | 3447 | 112449 | 815886 | 49673342 |
Blood iron abnormal | 527.72 | 9.62 | 220 | 115676 | 3106 | 50486122 |
Exposure during pregnancy | 509.36 | 9.62 | 958 | 114938 | 120057 | 50369171 |
Drug intolerance | 364.33 | 9.62 | 1216 | 114680 | 217888 | 50271340 |
Colitis ulcerative | 337.75 | 9.62 | 292 | 115604 | 16562 | 50472666 |
Treatment failure | 314.63 | 9.62 | 855 | 115041 | 136782 | 50352446 |
Premature delivery | 255.91 | 9.62 | 293 | 115603 | 23370 | 50465858 |
Cytomegalovirus infection | 240.66 | 9.62 | 249 | 115647 | 17713 | 50471515 |
Death | 227.62 | 9.62 | 246 | 115650 | 325133 | 50164095 |
Product use in unapproved indication | 219.58 | 9.62 | 673 | 115223 | 115146 | 50374082 |
Intestinal stenosis | 219.23 | 9.62 | 110 | 115786 | 2430 | 50486798 |
Lupus-like syndrome | 195.34 | 9.62 | 167 | 115729 | 9324 | 50479904 |
Cushingoid | 194.90 | 9.62 | 144 | 115752 | 6501 | 50482727 |
Fall | 192.09 | 9.62 | 294 | 115602 | 334638 | 50154590 |
Condition aggravated | 184.24 | 9.62 | 1237 | 114659 | 295821 | 50193407 |
Fistula | 178.17 | 9.62 | 149 | 115747 | 8069 | 50481159 |
Bone erosion | 176.71 | 9.62 | 173 | 115723 | 11514 | 50477714 |
Demyelination | 170.95 | 9.62 | 128 | 115768 | 5898 | 50483330 |
SLE arthritis | 165.12 | 9.62 | 60 | 115836 | 570 | 50488658 |
Anal fistula | 163.97 | 9.62 | 93 | 115803 | 2649 | 50486579 |
Ileal stenosis | 161.06 | 9.62 | 75 | 115821 | 1397 | 50487831 |
Fatigue | 160.34 | 9.62 | 959 | 114937 | 706642 | 49782586 |
Drug level below therapeutic | 159.28 | 9.62 | 102 | 115794 | 3638 | 50485590 |
Rheumatoid arthritis | 152.63 | 9.62 | 887 | 115009 | 201663 | 50287565 |
Premature labour | 151.76 | 9.62 | 158 | 115738 | 11318 | 50477910 |
Post transplant lymphoproliferative disorder | 150.78 | 9.62 | 103 | 115793 | 4101 | 50485127 |
Therapeutic response decreased | 144.24 | 9.62 | 328 | 115568 | 46903 | 50442325 |
Therapeutic product effect incomplete | 143.81 | 9.62 | 499 | 115397 | 91016 | 50398212 |
Disease recurrence | 140.07 | 9.62 | 200 | 115696 | 19881 | 50469347 |
Frequent bowel movements | 139.88 | 9.62 | 166 | 115730 | 13752 | 50475476 |
Crohn's disease | 139.78 | 9.62 | 103 | 115793 | 4630 | 50484598 |
Proteinuria | 139.57 | 9.62 | 181 | 115715 | 16416 | 50472812 |
Cholestasis of pregnancy | 137.48 | 9.62 | 62 | 115834 | 1069 | 50488159 |
Elbow deformity | 128.44 | 9.62 | 63 | 115833 | 1323 | 50487905 |
Maternal exposure during pregnancy | 127.05 | 9.62 | 710 | 115186 | 159068 | 50330160 |
Intentional product use issue | 126.61 | 9.62 | 426 | 115470 | 76492 | 50412736 |
Faecal calprotectin increased | 125.93 | 9.62 | 72 | 115824 | 2083 | 50487145 |
Epstein-Barr virus infection | 125.74 | 9.62 | 114 | 115782 | 6883 | 50482345 |
Glossodynia | 121.89 | 9.62 | 56 | 115840 | 115513 | 50373715 |
Large intestinal stenosis | 121.11 | 9.62 | 65 | 115831 | 1657 | 50487571 |
Intestinal resection | 119.66 | 9.62 | 72 | 115824 | 2295 | 50486933 |
Hyponatraemia | 119.13 | 9.62 | 36 | 115860 | 96103 | 50393125 |
Vasculitis | 116.74 | 9.62 | 152 | 115744 | 13839 | 50475389 |
Abortion spontaneous | 116.51 | 9.62 | 280 | 115616 | 41492 | 50447736 |
Transplant rejection | 115.92 | 9.62 | 126 | 115770 | 9483 | 50479745 |
Confusional state | 114.49 | 9.62 | 155 | 115741 | 185773 | 50303455 |
Toxicity to various agents | 112.78 | 9.62 | 196 | 115700 | 212303 | 50276925 |
Impaired gastric emptying | 111.65 | 9.62 | 118 | 115778 | 8600 | 50480628 |
Product dose omission issue | 109.46 | 9.62 | 157 | 115739 | 183681 | 50305547 |
Pre-eclampsia | 108.61 | 9.62 | 112 | 115784 | 7932 | 50481296 |
Malignant neoplasm progression | 108.35 | 9.62 | 14 | 115882 | 68110 | 50421118 |
Arthritis | 107.26 | 9.62 | 438 | 115458 | 86283 | 50402945 |
Somnolence | 105.05 | 9.62 | 120 | 115776 | 154865 | 50334363 |
Pain | 104.87 | 9.62 | 837 | 115059 | 578066 | 49911162 |
Diffuse large B-cell lymphoma | 103.22 | 9.62 | 93 | 115803 | 5569 | 50483659 |
Kidney transplant rejection | 102.78 | 9.62 | 80 | 115816 | 3907 | 50485321 |
Anal abscess | 101.95 | 9.62 | 78 | 115818 | 3713 | 50485515 |
Haematochezia | 98.26 | 9.62 | 255 | 115641 | 39627 | 50449601 |
Haemophagocytic lymphohistiocytosis | 96.88 | 9.62 | 109 | 115787 | 8524 | 50480704 |
Hepatic cirrhosis | 95.63 | 9.62 | 156 | 115740 | 17421 | 50471807 |
Ankylosing spondylitis | 93.58 | 9.62 | 98 | 115798 | 7067 | 50482161 |
Abscess | 93.50 | 9.62 | 138 | 115758 | 14134 | 50475094 |
Pemphigus | 91.68 | 9.62 | 84 | 115812 | 120082 | 50369146 |
Product use issue | 91.51 | 9.62 | 621 | 115275 | 148854 | 50340374 |
Drug abuse | 91.19 | 9.62 | 14 | 115882 | 59832 | 50429396 |
Lupus nephritis | 89.96 | 9.62 | 60 | 115836 | 2295 | 50486933 |
Drug hypersensitivity | 89.90 | 9.62 | 924 | 114972 | 250086 | 50239142 |
Abdominal pain | 89.13 | 9.62 | 879 | 115017 | 235349 | 50253879 |
Red blood cell sedimentation rate increased | 88.36 | 9.62 | 203 | 115693 | 29213 | 50460015 |
Pancreatitis | 87.61 | 9.62 | 255 | 115641 | 42359 | 50446869 |
Therapeutic product effect decreased | 87.35 | 9.62 | 572 | 115324 | 135478 | 50353750 |
Inflammation | 86.48 | 9.62 | 307 | 115589 | 56605 | 50432623 |
Atrial fibrillation | 86.44 | 9.62 | 64 | 115832 | 101681 | 50387547 |
Antinuclear antibody positive | 85.90 | 9.62 | 88 | 115808 | 6184 | 50483044 |
Overdose | 85.67 | 9.62 | 62 | 115834 | 99665 | 50389563 |
Joint dislocation | 84.78 | 9.62 | 122 | 115774 | 12211 | 50477017 |
Electrocardiogram QT prolonged | 84.13 | 9.62 | 10 | 115886 | 51876 | 50437352 |
Exostosis | 84.13 | 9.62 | 118 | 115778 | 11535 | 50477693 |
Constipation | 83.26 | 9.62 | 189 | 115707 | 185519 | 50303709 |
Hypotension | 81.42 | 9.62 | 272 | 115624 | 235197 | 50254031 |
Cardiac failure congestive | 81.32 | 9.62 | 46 | 115850 | 84336 | 50404892 |
Cytomegalovirus viraemia | 81.26 | 9.62 | 75 | 115821 | 4634 | 50484594 |
Cerebrovascular accident | 81.15 | 9.62 | 59 | 115837 | 94621 | 50394607 |
Anaphylactic reaction | 80.78 | 9.62 | 290 | 115606 | 53765 | 50435463 |
Lung transplant rejection | 80.49 | 9.62 | 38 | 115858 | 731 | 50488497 |
Basal cell carcinoma | 80.12 | 9.62 | 170 | 115726 | 23186 | 50466042 |
Pancytopenia | 79.51 | 9.62 | 392 | 115504 | 83638 | 50405590 |
Swelling | 78.74 | 9.62 | 219 | 115677 | 200653 | 50288575 |
Osteoporosis | 78.68 | 9.62 | 254 | 115642 | 44625 | 50444603 |
Pleuritic pain | 78.36 | 9.62 | 85 | 115811 | 6381 | 50482847 |
Normal newborn | 77.69 | 9.62 | 86 | 115810 | 6605 | 50482623 |
Rheumatoid nodule | 77.53 | 9.62 | 119 | 115777 | 12616 | 50476612 |
Gestational hypertension | 75.00 | 9.62 | 52 | 115844 | 2121 | 50487107 |
Disseminated tuberculosis | 74.27 | 9.62 | 55 | 115841 | 2491 | 50486737 |
Squamous cell carcinoma | 73.99 | 9.62 | 90 | 115806 | 7649 | 50481579 |
Hepatosplenic T-cell lymphoma | 73.92 | 9.62 | 33 | 115863 | 555 | 50488673 |
Diarrhoea haemorrhagic | 72.96 | 9.62 | 89 | 115807 | 7586 | 50481642 |
Tremor | 72.51 | 9.62 | 94 | 115802 | 114809 | 50374419 |
Joint stiffness | 71.81 | 9.62 | 191 | 115705 | 30117 | 50459111 |
Dizziness | 70.55 | 9.62 | 484 | 115412 | 345885 | 50143343 |
Arthralgia | 70.54 | 9.62 | 1402 | 114494 | 437300 | 50051928 |
Leukopenia | 70.39 | 9.62 | 324 | 115572 | 67204 | 50422024 |
Pneumocystis jirovecii pneumonia | 70.30 | 9.62 | 123 | 115773 | 14540 | 50474688 |
Asthenia | 69.41 | 9.62 | 437 | 115459 | 318605 | 50170623 |
Epstein-Barr virus associated lymphoproliferative disorder | 69.30 | 9.62 | 45 | 115851 | 1644 | 50487584 |
Clostridium difficile infection | 69.29 | 9.62 | 169 | 115727 | 25270 | 50463958 |
Granulomatosis with polyangiitis | 69.09 | 9.62 | 46 | 115850 | 1754 | 50487474 |
Synovial fluid analysis | 68.09 | 9.62 | 44 | 115852 | 1594 | 50487634 |
Stomatitis | 68.06 | 9.62 | 79 | 115817 | 101265 | 50387963 |
C-reactive protein increased | 67.86 | 9.62 | 317 | 115579 | 66157 | 50423071 |
Hypokalaemia | 67.71 | 9.62 | 61 | 115835 | 87931 | 50401297 |
Hand deformity | 67.41 | 9.62 | 78 | 115818 | 100121 | 50389107 |
Intestinal obstruction | 67.37 | 9.62 | 171 | 115725 | 26212 | 50463016 |
Premature baby | 67.03 | 9.62 | 137 | 115759 | 18200 | 50471028 |
Hair follicle tumour benign | 66.14 | 9.62 | 27 | 115869 | 360 | 50488868 |
Contusion | 65.55 | 9.62 | 97 | 115799 | 112086 | 50377142 |
Abdominal discomfort | 65.01 | 9.62 | 291 | 115605 | 231350 | 50257878 |
Scleritis | 64.81 | 9.62 | 56 | 115840 | 3171 | 50486057 |
Immunosuppressant drug level decreased | 64.27 | 9.62 | 34 | 115862 | 841 | 50488387 |
Progressive multifocal leukoencephalopathy | 64.12 | 9.62 | 103 | 115793 | 11354 | 50477874 |
Gastrointestinal inflammation | 63.83 | 9.62 | 65 | 115831 | 4535 | 50484693 |
Cardio-respiratory arrest | 63.53 | 9.62 | 22 | 115874 | 53870 | 50435358 |
Liver function test increased | 63.35 | 9.62 | 164 | 115732 | 25442 | 50463786 |
Tenosynovitis stenosans | 62.54 | 9.62 | 47 | 115849 | 2177 | 50487051 |
Loss of consciousness | 62.17 | 9.62 | 89 | 115807 | 104264 | 50384964 |
Syncope | 61.22 | 9.62 | 88 | 115808 | 102914 | 50386314 |
Anti-neutrophil cytoplasmic antibody positive vasculitis | 60.74 | 9.62 | 47 | 115849 | 2275 | 50486953 |
Colectomy | 60.44 | 9.62 | 45 | 115851 | 2055 | 50487173 |
Febrile neutropenia | 59.48 | 9.62 | 82 | 115814 | 97585 | 50391643 |
Blood pressure fluctuation | 59.43 | 9.62 | 199 | 115697 | 35624 | 50453604 |
Gastrointestinal lymphoma | 59.23 | 9.62 | 16 | 115880 | 48 | 50489180 |
Hypogammaglobulinaemia | 58.96 | 9.62 | 69 | 115827 | 5630 | 50483598 |
Insomnia | 58.36 | 9.62 | 205 | 115691 | 174660 | 50314568 |
Discomfort | 58.31 | 9.62 | 99 | 115797 | 108281 | 50380947 |
Muscle injury | 58.11 | 9.62 | 8 | 115888 | 37103 | 50452125 |
Erythema nodosum | 57.55 | 9.62 | 57 | 115839 | 3846 | 50485382 |
Intentional overdose | 57.50 | 9.62 | 36 | 115860 | 62468 | 50426760 |
Histoplasmosis disseminated | 57.07 | 9.62 | 36 | 115860 | 1250 | 50487978 |
Autoimmune hepatitis | 57.07 | 9.62 | 78 | 115818 | 7441 | 50481787 |
Diabetes mellitus | 56.95 | 9.62 | 243 | 115653 | 48790 | 50440438 |
Wound | 56.59 | 9.62 | 97 | 115799 | 105697 | 50383531 |
Decreased appetite | 56.00 | 9.62 | 253 | 115643 | 200670 | 50288558 |
Anxiety | 54.84 | 9.62 | 215 | 115681 | 177391 | 50311837 |
Lymphoproliferative disorder | 53.92 | 9.62 | 48 | 115848 | 2829 | 50486399 |
Pulmonary mass | 53.89 | 9.62 | 127 | 115769 | 18578 | 50470650 |
Neutrophil count decreased | 53.89 | 9.62 | 19 | 115877 | 46007 | 50443221 |
Caesarean section | 53.83 | 9.62 | 114 | 115782 | 15525 | 50473703 |
Overlap syndrome | 53.05 | 9.62 | 27 | 115869 | 615 | 50488613 |
Lymphopenia | 52.77 | 9.62 | 113 | 115783 | 15508 | 50473720 |
Dyspnoea | 52.76 | 9.62 | 910 | 114986 | 546698 | 49942530 |
Ulcer | 52.69 | 9.62 | 132 | 115764 | 20068 | 50469160 |
Sedation | 51.92 | 9.62 | 5 | 115891 | 30605 | 50458623 |
Pulmonary tuberculosis | 51.48 | 9.62 | 56 | 115840 | 4217 | 50485011 |
Lupus vasculitis | 50.77 | 9.62 | 24 | 115872 | 463 | 50488765 |
Osteonecrosis | 50.43 | 9.62 | 139 | 115757 | 22378 | 50466850 |
Central nervous system lymphoma | 50.27 | 9.62 | 34 | 115862 | 1331 | 50487897 |
Hallucination | 50.12 | 9.62 | 22 | 115874 | 46635 | 50442593 |
Retinitis | 48.94 | 9.62 | 38 | 115858 | 1849 | 50487379 |
Tuberculosis | 48.88 | 9.62 | 85 | 115811 | 9998 | 50479230 |
Foot deformity | 48.51 | 9.62 | 124 | 115772 | 19086 | 50470142 |
Drug level decreased | 48.42 | 9.62 | 67 | 115829 | 6466 | 50482762 |
Premature separation of placenta | 48.39 | 9.62 | 36 | 115860 | 1642 | 50487586 |
C-reactive protein abnormal | 48.38 | 9.62 | 157 | 115739 | 27652 | 50461576 |
Inappropriate schedule of product administration | 47.89 | 9.62 | 305 | 115591 | 71526 | 50417702 |
Balance disorder | 47.41 | 9.62 | 55 | 115841 | 70535 | 50418693 |
Interstitial lung disease | 47.41 | 9.62 | 244 | 115652 | 52932 | 50436296 |
Cardiac arrest | 47.25 | 9.62 | 74 | 115822 | 83577 | 50405651 |
Therapeutic product effect variable | 47.09 | 9.62 | 30 | 115866 | 1060 | 50488168 |
Irritable bowel syndrome | 46.81 | 9.62 | 30 | 115866 | 51411 | 50437817 |
B-cell lymphoma | 46.64 | 9.62 | 45 | 115851 | 2940 | 50486288 |
Seizure | 46.53 | 9.62 | 128 | 115768 | 117746 | 50371482 |
Agitation | 46.08 | 9.62 | 33 | 115863 | 53351 | 50435877 |
Injection site swelling | 45.98 | 9.62 | 19 | 115877 | 41754 | 50447474 |
Listeriosis | 45.50 | 9.62 | 32 | 115864 | 1336 | 50487892 |
Immunosuppressant drug level increased | 45.43 | 9.62 | 45 | 115851 | 3037 | 50486191 |
Intestinal fistula | 45.20 | 9.62 | 26 | 115870 | 761 | 50488467 |
Duodenal ulcer perforation | 45.19 | 9.62 | 24 | 115872 | 45587 | 50443641 |
Anal fissure | 45.14 | 9.62 | 45 | 115851 | 3060 | 50486168 |
Angiocentric lymphoma | 44.83 | 9.62 | 23 | 115873 | 533 | 50488695 |
Platelet count decreased | 44.70 | 9.62 | 103 | 115793 | 100623 | 50388605 |
Histoplasmosis | 44.70 | 9.62 | 35 | 115861 | 1724 | 50487504 |
Epstein-Barr virus test positive | 44.64 | 9.62 | 23 | 115873 | 538 | 50488690 |
Folliculitis | 44.56 | 9.62 | 17 | 115879 | 39208 | 50450020 |
Papilloma viral infection | 44.46 | 9.62 | 31 | 115865 | 1276 | 50487952 |
Female genital tract fistula | 44.09 | 9.62 | 48 | 115848 | 3618 | 50485610 |
Cytomegalovirus colitis | 43.98 | 9.62 | 36 | 115860 | 1891 | 50487337 |
Joint swelling | 43.78 | 9.62 | 797 | 115099 | 244489 | 50244739 |
Depressed level of consciousness | 43.69 | 9.62 | 33 | 115863 | 51920 | 50437308 |
Chronic allograft nephropathy | 43.60 | 9.62 | 24 | 115872 | 644 | 50488584 |
Depression | 43.31 | 9.62 | 213 | 115683 | 165210 | 50324018 |
Blood glucose increased | 43.30 | 9.62 | 60 | 115836 | 71264 | 50417964 |
Renal impairment | 43.10 | 9.62 | 309 | 115587 | 75352 | 50413876 |
Impaired work ability | 43.04 | 9.62 | 96 | 115800 | 13544 | 50475684 |
Nicotinic acid deficiency | 43.03 | 9.62 | 12 | 115884 | 42 | 50489186 |
Suicidal ideation | 41.88 | 9.62 | 39 | 115857 | 55346 | 50433882 |
Neoplasm progression | 41.82 | 9.62 | 8 | 115888 | 29149 | 50460079 |
Premature rupture of membranes | 41.74 | 9.62 | 52 | 115844 | 4528 | 50484700 |
Injection site erythema | 41.65 | 9.62 | 67 | 115829 | 74869 | 50414359 |
Back pain | 41.54 | 9.62 | 314 | 115582 | 219716 | 50269512 |
Squamous cell carcinoma of skin | 41.25 | 9.62 | 55 | 115841 | 5123 | 50484105 |
Mycobacterial infection | 41.09 | 9.62 | 32 | 115864 | 1564 | 50487664 |
Phospholipidosis | 40.83 | 9.62 | 12 | 115884 | 53 | 50489175 |
Coma | 40.76 | 9.62 | 42 | 115854 | 56837 | 50432391 |
Blister | 40.67 | 9.62 | 84 | 115812 | 85334 | 50403894 |
Product label confusion | 40.42 | 9.62 | 21 | 115875 | 500 | 50488728 |
Hyperkalaemia | 39.86 | 9.62 | 31 | 115865 | 48058 | 50441170 |
Small intestinal obstruction | 39.83 | 9.62 | 103 | 115793 | 15965 | 50473263 |
Foetal death | 39.71 | 9.62 | 69 | 115827 | 8111 | 50481117 |
Fungal endocarditis | 39.42 | 9.62 | 16 | 115880 | 210 | 50489018 |
Bradycardia | 39.31 | 9.62 | 54 | 115842 | 64372 | 50424856 |
Muscle fatigue | 39.29 | 9.62 | 36 | 115860 | 2203 | 50487025 |
Cholangitis sclerosing | 39.14 | 9.62 | 28 | 115868 | 1201 | 50488027 |
Foetal growth restriction | 39.04 | 9.62 | 61 | 115835 | 6566 | 50482662 |
Pulmonary fibrosis | 38.99 | 9.62 | 134 | 115762 | 24303 | 50464925 |
Feeling abnormal | 38.66 | 9.62 | 152 | 115744 | 125340 | 50363888 |
Orthostatic hypotension | 38.43 | 9.62 | 10 | 115886 | 29471 | 50459757 |
Epicondylitis | 38.08 | 9.62 | 33 | 115863 | 1876 | 50487352 |
Hypoglycaemia | 37.90 | 9.62 | 40 | 115856 | 53541 | 50435687 |
Subcutaneous abscess | 37.59 | 9.62 | 51 | 115845 | 4831 | 50484397 |
Helicobacter infection | 37.58 | 9.62 | 35 | 115861 | 49667 | 50439561 |
Wrong technique in product usage process | 37.55 | 9.62 | 43 | 115853 | 55467 | 50433761 |
Clear cell renal cell carcinoma | 37.38 | 9.62 | 27 | 115869 | 1176 | 50488052 |
Low birth weight baby | 37.28 | 9.62 | 56 | 115840 | 5825 | 50483403 |
Dehydration | 37.25 | 9.62 | 201 | 115695 | 152248 | 50336980 |
Bone pain | 37.22 | 9.62 | 32 | 115864 | 47197 | 50442031 |
Serotonin syndrome | 37.14 | 9.62 | 6 | 115890 | 24707 | 50464521 |
Episcleritis | 37.00 | 9.62 | 23 | 115873 | 778 | 50488450 |
Full blood count decreased | 36.99 | 9.62 | 4 | 115892 | 22342 | 50466886 |
Injection site inflammation | 36.87 | 9.62 | 41 | 115855 | 3164 | 50486064 |
Musculoskeletal stiffness | 36.81 | 9.62 | 453 | 115443 | 128028 | 50361200 |
Bronchiectasis | 36.60 | 9.62 | 76 | 115820 | 10207 | 50479021 |
Live birth | 36.46 | 9.62 | 101 | 115795 | 16307 | 50472921 |
Ileostomy | 36.41 | 9.62 | 26 | 115870 | 1112 | 50488116 |
Metabolic acidosis | 36.21 | 9.62 | 22 | 115874 | 38803 | 50450425 |
Intentional self-injury | 36.14 | 9.62 | 5 | 115891 | 23107 | 50466121 |
Antiphospholipid syndrome | 36.01 | 9.62 | 29 | 115867 | 1488 | 50487740 |
Respiratory arrest | 35.80 | 9.62 | 12 | 115884 | 29997 | 50459231 |
Proctitis | 35.80 | 9.62 | 32 | 115864 | 1896 | 50487332 |
Pneumonia cytomegaloviral | 35.61 | 9.62 | 32 | 115864 | 1909 | 50487319 |
Pregnancy | 35.44 | 9.62 | 148 | 115748 | 29429 | 50459799 |
Bone marrow failure | 35.29 | 9.62 | 141 | 115755 | 27483 | 50461745 |
Panniculitis | 35.27 | 9.62 | 67 | 115829 | 8436 | 50480792 |
Intentional product misuse | 35.23 | 9.62 | 33 | 115863 | 46701 | 50442527 |
Immunosuppression | 35.21 | 9.62 | 62 | 115834 | 7364 | 50481864 |
Intestinal fibrosis | 35.18 | 9.62 | 13 | 115883 | 130 | 50489098 |
Disseminated cytomegaloviral infection | 35.18 | 9.62 | 14 | 115882 | 174 | 50489054 |
Aphthous ulcer | 35.04 | 9.62 | 76 | 115820 | 10521 | 50478707 |
Crepitations | 34.92 | 9.62 | 56 | 115840 | 6163 | 50483065 |
Plasmablastic lymphoma | 34.89 | 9.62 | 14 | 115882 | 178 | 50489050 |
Palmar-plantar erythrodysaesthesia syndrome | 34.85 | 9.62 | 3 | 115893 | 20095 | 50469133 |
Abdominal adhesions | 34.48 | 9.62 | 37 | 115859 | 2743 | 50486485 |
Mycobacterium abscessus infection | 34.45 | 9.62 | 19 | 115877 | 512 | 50488716 |
Inflammatory bowel disease | 34.42 | 9.62 | 41 | 115855 | 3409 | 50485819 |
White blood cell count decreased | 34.30 | 9.62 | 144 | 115752 | 116578 | 50372650 |
Injection site bruising | 34.06 | 9.62 | 21 | 115875 | 36747 | 50452481 |
Impaired healing | 33.75 | 9.62 | 68 | 115828 | 69718 | 50419510 |
Drug specific antibody present | 33.56 | 9.62 | 40 | 115856 | 3328 | 50485900 |
Chronic obstructive pulmonary disease | 33.40 | 9.62 | 44 | 115852 | 53391 | 50435837 |
Drug ineffective for unapproved indication | 33.35 | 9.62 | 116 | 115780 | 21165 | 50468063 |
Nodular regenerative hyperplasia | 33.34 | 9.62 | 15 | 115881 | 257 | 50488971 |
Secondary immunodeficiency | 33.17 | 9.62 | 25 | 115871 | 1163 | 50488065 |
Liver transplant rejection | 33.15 | 9.62 | 26 | 115870 | 1284 | 50487944 |
Dermatomyositis | 32.68 | 9.62 | 32 | 115864 | 2129 | 50487099 |
Neuropathy peripheral | 32.54 | 9.62 | 113 | 115783 | 96644 | 50392584 |
Colitis | 32.42 | 9.62 | 174 | 115722 | 38355 | 50450873 |
Foetal exposure during pregnancy | 32.08 | 9.62 | 136 | 115760 | 27223 | 50462005 |
Nausea | 31.95 | 9.62 | 1307 | 114589 | 704091 | 49785137 |
Multiple sclerosis relapse | 31.61 | 9.62 | 31 | 115865 | 42933 | 50446295 |
Natural killer-cell leukaemia | 31.61 | 9.62 | 11 | 115885 | 91 | 50489137 |
Heart transplant rejection | 31.54 | 9.62 | 17 | 115879 | 437 | 50488791 |
Enterocutaneous fistula | 31.05 | 9.62 | 24 | 115872 | 1160 | 50488068 |
Uveitis | 31.04 | 9.62 | 67 | 115829 | 9243 | 50479985 |
Cervical dysplasia | 30.97 | 9.62 | 35 | 115861 | 2750 | 50486478 |
Suicide attempt | 30.92 | 9.62 | 44 | 115852 | 51688 | 50437540 |
Pyoderma gangrenosum | 30.50 | 9.62 | 35 | 115861 | 2796 | 50486432 |
Hyperhidrosis | 30.37 | 9.62 | 104 | 115792 | 89322 | 50399906 |
Mycobacterium avium complex infection | 30.21 | 9.62 | 33 | 115863 | 2497 | 50486731 |
Coombs positive haemolytic anaemia | 30.20 | 9.62 | 15 | 115881 | 324 | 50488904 |
Restlessness | 30.14 | 9.62 | 10 | 115886 | 25163 | 50464065 |
Renal mass | 30.13 | 9.62 | 29 | 115867 | 1889 | 50487339 |
Red blood cell sedimentation rate abnormal | 30.00 | 9.62 | 94 | 115802 | 16249 | 50472979 |
Drug withdrawal syndrome | 29.97 | 9.62 | 10 | 115886 | 25071 | 50464157 |
Trichodysplasia spinulosa | 29.94 | 9.62 | 17 | 115879 | 485 | 50488743 |
Myositis | 29.93 | 9.62 | 60 | 115836 | 7860 | 50481368 |
Eye infection toxoplasmal | 29.81 | 9.62 | 14 | 115882 | 266 | 50488962 |
Accidental exposure to product | 29.72 | 9.62 | 8 | 115888 | 23049 | 50466179 |
Bronchitis | 29.68 | 9.62 | 130 | 115766 | 104029 | 50385199 |
Drug tolerance | 29.59 | 9.62 | 46 | 115850 | 4930 | 50484298 |
Meningitis cryptococcal | 29.57 | 9.62 | 23 | 115873 | 1122 | 50488106 |
Jaw fracture | 29.37 | 9.62 | 32 | 115864 | 2414 | 50486814 |
Scleroderma renal crisis | 29.25 | 9.62 | 14 | 115882 | 278 | 50488950 |
Rhegmatogenous retinal detachment | 29.25 | 9.62 | 10 | 115886 | 78 | 50489150 |
Chorioretinopathy | 29.06 | 9.62 | 20 | 115876 | 806 | 50488422 |
Adverse reaction | 28.87 | 9.62 | 62 | 115834 | 8524 | 50480704 |
Device dislocation | 28.68 | 9.62 | 7 | 115889 | 21539 | 50467689 |
Synovial cyst | 28.65 | 9.62 | 60 | 115836 | 8106 | 50481122 |
Hepatic fibrosis | 28.62 | 9.62 | 36 | 115860 | 3166 | 50486062 |
Dyskinesia | 28.58 | 9.62 | 14 | 115882 | 27847 | 50461381 |
Acute kidney injury | 28.44 | 9.62 | 360 | 115536 | 227698 | 50261530 |
Fluid retention | 28.41 | 9.62 | 45 | 115851 | 50604 | 50438624 |
Complications of bone marrow transplant | 28.39 | 9.62 | 16 | 115880 | 450 | 50488778 |
Lactic acidosis | 28.29 | 9.62 | 21 | 115875 | 33334 | 50455894 |
Extrapulmonary tuberculosis | 28.28 | 9.62 | 14 | 115882 | 300 | 50488928 |
Rectal cancer metastatic | 28.17 | 9.62 | 13 | 115883 | 237 | 50488991 |
Ganglioneuroma | 28.06 | 9.62 | 11 | 115885 | 131 | 50489097 |
Myelosuppression | 27.88 | 9.62 | 81 | 115815 | 13436 | 50475792 |
Klebsiella infection | 27.78 | 9.62 | 55 | 115841 | 7139 | 50482089 |
Abscess intestinal | 27.62 | 9.62 | 24 | 115872 | 1369 | 50487859 |
Laryngeal disorder | 27.59 | 9.62 | 20 | 115876 | 876 | 50488352 |
Anogenital warts | 27.57 | 9.62 | 15 | 115881 | 393 | 50488835 |
Salmonellosis | 27.55 | 9.62 | 20 | 115876 | 878 | 50488350 |
Aspergillus infection | 27.38 | 9.62 | 53 | 115843 | 6768 | 50482460 |
Varicella zoster virus infection | 27.20 | 9.62 | 31 | 115865 | 2458 | 50486770 |
Neoplasm malignant | 27.12 | 9.62 | 117 | 115779 | 23598 | 50465630 |
Rectal abscess | 27.06 | 9.62 | 21 | 115875 | 1021 | 50488207 |
Nephrotic syndrome | 26.85 | 9.62 | 43 | 115853 | 4727 | 50484501 |
Antinuclear antibody negative | 26.76 | 9.62 | 12 | 115884 | 204 | 50489024 |
Abdominal abscess | 26.60 | 9.62 | 39 | 115857 | 3969 | 50485259 |
Encephalopathy | 26.37 | 9.62 | 23 | 115873 | 33688 | 50455540 |
Kaposi's sarcoma | 26.27 | 9.62 | 11 | 115885 | 157 | 50489071 |
Therapeutic reaction time decreased | 26.22 | 9.62 | 23 | 115873 | 1329 | 50487899 |
Plasma cell myeloma | 26.20 | 9.62 | 20 | 115876 | 31302 | 50457926 |
Nasopharyngitis | 26.17 | 9.62 | 299 | 115597 | 192628 | 50296600 |
Strongyloidiasis | 26.06 | 9.62 | 19 | 115877 | 840 | 50488388 |
Injury | 26.02 | 9.62 | 45 | 115851 | 48880 | 50440348 |
Eosinophilic granulomatosis with polyangiitis | 25.99 | 9.62 | 27 | 115869 | 1928 | 50487300 |
Wrist deformity | 25.90 | 9.62 | 26 | 115870 | 1783 | 50487445 |
Tractional retinal detachment | 25.78 | 9.62 | 8 | 115888 | 44 | 50489184 |
Thiopurine methyltransferase decreased | 25.75 | 9.62 | 13 | 115883 | 291 | 50488937 |
Mental status changes | 25.74 | 9.62 | 27 | 115869 | 36245 | 50452983 |
Urinary retention | 25.62 | 9.62 | 14 | 115882 | 26176 | 50463052 |
Somatic delusion | 25.51 | 9.62 | 16 | 115880 | 550 | 50488678 |
Medication error | 25.48 | 9.62 | 27 | 115869 | 36077 | 50453151 |
Tuberculosis of central nervous system | 25.47 | 9.62 | 13 | 115883 | 298 | 50488930 |
Rectal discharge | 25.45 | 9.62 | 15 | 115881 | 460 | 50488768 |
Meningoencephalitis viral | 25.43 | 9.62 | 13 | 115883 | 299 | 50488929 |
Congenital osteodystrophy | 25.21 | 9.62 | 7 | 115889 | 24 | 50489204 |
Blood calcium decreased | 25.19 | 9.62 | 8 | 115888 | 20698 | 50468530 |
Sleep disorder due to general medical condition, insomnia type | 25.15 | 9.62 | 21 | 115875 | 31426 | 50457802 |
Serum sickness | 25.11 | 9.62 | 30 | 115866 | 2502 | 50486726 |
Drug tolerance decreased | 25.10 | 9.62 | 61 | 115835 | 9099 | 50480129 |
Sleep disorder | 25.07 | 9.62 | 59 | 115837 | 57224 | 50432004 |
Joint effusion | 24.93 | 9.62 | 76 | 115820 | 12945 | 50476283 |
Cardiac failure | 24.77 | 9.62 | 90 | 115806 | 75950 | 50413278 |
Hypomagnesaemia | 24.74 | 9.62 | 11 | 115885 | 23145 | 50466083 |
Headache | 24.72 | 9.62 | 930 | 114966 | 505605 | 49983623 |
Herpes simplex hepatitis | 24.63 | 9.62 | 13 | 115883 | 320 | 50488908 |
Abscess rupture | 24.59 | 9.62 | 12 | 115884 | 249 | 50488979 |
Intestinal mucosal hypertrophy | 24.48 | 9.62 | 11 | 115885 | 188 | 50489040 |
Pneumonia aspiration | 24.43 | 9.62 | 21 | 115875 | 30983 | 50458245 |
Renal transplant failure | 24.34 | 9.62 | 16 | 115880 | 597 | 50488631 |
Cardiac disorder | 24.28 | 9.62 | 38 | 115858 | 42941 | 50446287 |
Product quality issue | 24.20 | 9.62 | 21 | 115875 | 30837 | 50458391 |
Antisynthetase syndrome | 24.14 | 9.62 | 8 | 115888 | 56 | 50489172 |
Ileectomy | 24.12 | 9.62 | 10 | 115886 | 139 | 50489089 |
Colectomy total | 24.06 | 9.62 | 10 | 115886 | 140 | 50489088 |
Infectious mononucleosis | 23.95 | 9.62 | 24 | 115872 | 1642 | 50487586 |
Bursitis infective | 23.95 | 9.62 | 21 | 115875 | 1213 | 50488015 |
Glomerulosclerosis | 23.88 | 9.62 | 13 | 115883 | 341 | 50488887 |
Unresponsive to stimuli | 23.80 | 9.62 | 21 | 115875 | 30588 | 50458640 |
Flank pain | 23.68 | 9.62 | 75 | 115821 | 13040 | 50476188 |
Sopor | 23.62 | 9.62 | 8 | 115888 | 19871 | 50469357 |
Injection site pain | 23.60 | 9.62 | 153 | 115743 | 110871 | 50378357 |
Lipase increased | 23.53 | 9.62 | 57 | 115839 | 8484 | 50480744 |
Varicella | 23.38 | 9.62 | 24 | 115872 | 1690 | 50487538 |
Dysgeusia | 23.35 | 9.62 | 33 | 115863 | 38883 | 50450345 |
Abdominal pain upper | 23.15 | 9.62 | 243 | 115653 | 159066 | 50330162 |
Cognitive disorder | 23.08 | 9.62 | 41 | 115855 | 44082 | 50445146 |
Accidental overdose | 22.97 | 9.62 | 8 | 115888 | 19525 | 50469703 |
Skin ulcer | 22.93 | 9.62 | 149 | 115747 | 35169 | 50454059 |
Arthritis enteropathic | 22.91 | 9.62 | 11 | 115885 | 220 | 50489008 |
Peripheral swelling | 22.81 | 9.62 | 333 | 115563 | 205603 | 50283625 |
Myasthenia gravis | 22.77 | 9.62 | 34 | 115862 | 3518 | 50485710 |
Conjunctivitis | 22.74 | 9.62 | 85 | 115811 | 16060 | 50473168 |
HELLP syndrome | 22.74 | 9.62 | 18 | 115878 | 901 | 50488327 |
Spinal cord infection | 22.53 | 9.62 | 15 | 115881 | 572 | 50488656 |
Tenosynovitis | 22.46 | 9.62 | 64 | 115832 | 10501 | 50478727 |
Gastrointestinal haemorrhage | 22.45 | 9.62 | 89 | 115807 | 73232 | 50415996 |
Cytomegalovirus hepatitis | 22.39 | 9.62 | 12 | 115884 | 305 | 50488923 |
Small intestinal stenosis | 22.30 | 9.62 | 14 | 115882 | 482 | 50488746 |
Body temperature fluctuation | 22.29 | 9.62 | 25 | 115871 | 1948 | 50487280 |
Hepatosplenomegaly | 22.28 | 9.62 | 27 | 115869 | 2285 | 50486943 |
Therapeutic response shortened | 22.19 | 9.62 | 51 | 115845 | 7338 | 50481890 |
Oesophageal squamous cell carcinoma | 21.98 | 9.62 | 9 | 115887 | 121 | 50489107 |
Intestinal anastomosis | 21.97 | 9.62 | 12 | 115884 | 317 | 50488911 |
Myocardial infarction | 21.94 | 9.62 | 117 | 115779 | 88910 | 50400318 |
Gastrointestinal stoma output abnormal | 21.91 | 9.62 | 7 | 115889 | 43 | 50489185 |
Emotional distress | 21.88 | 9.62 | 20 | 115876 | 28643 | 50460585 |
Nocardiosis | 21.77 | 9.62 | 23 | 115873 | 1675 | 50487553 |
Anaplastic large cell lymphoma T- and null-cell types | 21.77 | 9.62 | 7 | 115889 | 44 | 50489184 |
Corynebacterium infection | 21.76 | 9.62 | 13 | 115883 | 409 | 50488819 |
Congenital syphilitic osteochondritis | 21.74 | 9.62 | 6 | 115890 | 20 | 50489208 |
T-cell lymphoma | 21.48 | 9.62 | 15 | 115881 | 619 | 50488609 |
Proctalgia | 21.47 | 9.62 | 40 | 115856 | 4963 | 50484265 |
Primary biliary cholangitis | 21.44 | 9.62 | 19 | 115877 | 1113 | 50488115 |
Hydrops foetalis | 21.44 | 9.62 | 12 | 115884 | 333 | 50488895 |
Pneumocystis jirovecii infection | 21.40 | 9.62 | 20 | 115876 | 1255 | 50487973 |
Porokeratosis | 21.40 | 9.62 | 9 | 115887 | 130 | 50489098 |
Vomiting | 21.36 | 9.62 | 851 | 115045 | 459907 | 50029321 |
Delirium | 21.35 | 9.62 | 34 | 115862 | 38158 | 50451070 |
Skin lesion | 21.34 | 9.62 | 119 | 115777 | 26608 | 50462620 |
Femur fracture | 21.28 | 9.62 | 33 | 115863 | 37431 | 50451797 |
Disturbance in attention | 21.26 | 9.62 | 24 | 115872 | 31162 | 50458066 |
Hepatitis | 21.23 | 9.62 | 134 | 115762 | 31319 | 50457909 |
Abnormal faeces | 21.16 | 9.62 | 36 | 115860 | 4160 | 50485068 |
Rectal haemorrhage | 21.10 | 9.62 | 156 | 115740 | 38402 | 50450826 |
Aplasia pure red cell | 21.04 | 9.62 | 36 | 115860 | 4179 | 50485049 |
Antineutrophil cytoplasmic antibody increased | 21.01 | 9.62 | 7 | 115889 | 50 | 50489178 |
Candida infection | 21 | 9.62 | 108 | 115788 | 23415 | 50465813 |
Oedema peripheral | 20.95 | 9.62 | 246 | 115650 | 157715 | 50331513 |
Lymphadenopathy | 20.95 | 9.62 | 140 | 115756 | 33359 | 50455869 |
Therapy interrupted | 20.86 | 9.62 | 10 | 115886 | 20142 | 50469086 |
Atypical haemolytic uraemic syndrome | 20.82 | 9.62 | 14 | 115882 | 543 | 50488685 |
Anorectal disorder | 20.79 | 9.62 | 21 | 115875 | 1451 | 50487777 |
Brain abscess | 20.76 | 9.62 | 23 | 115873 | 1768 | 50487460 |
Cholesteatoma | 20.68 | 9.62 | 9 | 115887 | 142 | 50489086 |
Congenital cytomegalovirus infection | 20.65 | 9.62 | 5 | 115891 | 8 | 50489220 |
Small intestine carcinoma | 20.48 | 9.62 | 12 | 115884 | 364 | 50488864 |
Fistula of small intestine | 20.47 | 9.62 | 11 | 115885 | 281 | 50488947 |
Disorientation | 20.40 | 9.62 | 31 | 115865 | 35453 | 50453775 |
Dysplasia | 20.32 | 9.62 | 15 | 115881 | 676 | 50488552 |
Renal tubular atrophy | 20.30 | 9.62 | 14 | 115882 | 566 | 50488662 |
Fistula discharge | 20.28 | 9.62 | 17 | 115879 | 923 | 50488305 |
Sleep apnoea syndrome | 20.27 | 9.62 | 15 | 115881 | 23853 | 50465375 |
Appendicitis | 20.20 | 9.62 | 46 | 115850 | 6578 | 50482650 |
Anal cancer | 20.19 | 9.62 | 13 | 115883 | 468 | 50488760 |
Cerebral toxoplasmosis | 20.16 | 9.62 | 15 | 115881 | 684 | 50488544 |
Sebaceous carcinoma | 20.15 | 9.62 | 6 | 115890 | 28 | 50489200 |
Lupus myocarditis | 20.10 | 9.62 | 7 | 115889 | 58 | 50489170 |
International normalised ratio increased | 20.06 | 9.62 | 43 | 115853 | 43109 | 50446119 |
Neuromyelitis optica spectrum disorder | 20.05 | 9.62 | 16 | 115880 | 810 | 50488418 |
Cough | 20.00 | 9.62 | 411 | 115485 | 240853 | 50248375 |
Infusion related reaction | 19.94 | 9.62 | 519 | 115377 | 169038 | 50320190 |
Herpes simplex reactivation | 19.87 | 9.62 | 12 | 115884 | 385 | 50488843 |
Actinic keratosis | 19.84 | 9.62 | 25 | 115871 | 2202 | 50487026 |
Chronic hepatitis | 19.82 | 9.62 | 16 | 115880 | 824 | 50488404 |
Dementia | 19.79 | 9.62 | 6 | 115890 | 15991 | 50473237 |
Paraesthesia | 19.75 | 9.62 | 178 | 115718 | 120065 | 50369163 |
Gastrointestinal scarring | 19.72 | 9.62 | 10 | 115886 | 226 | 50489002 |
Ileostomy closure | 19.71 | 9.62 | 8 | 115888 | 105 | 50489123 |
Gestational diabetes | 19.70 | 9.62 | 49 | 115847 | 7416 | 50481812 |
Transaminases increased | 19.69 | 9.62 | 120 | 115776 | 27704 | 50461524 |
Gastrointestinal fistula | 19.62 | 9.62 | 12 | 115884 | 394 | 50488834 |
Pericarditis | 19.62 | 9.62 | 103 | 115793 | 78586 | 50410642 |
Granuloma skin | 19.55 | 9.62 | 42 | 115854 | 5776 | 50483452 |
Weight decreased | 19.43 | 9.62 | 653 | 115243 | 220592 | 50268636 |
Thrombotic microangiopathy | 19.42 | 9.62 | 54 | 115842 | 8737 | 50480491 |
Rectal stenosis | 19.41 | 9.62 | 9 | 115887 | 166 | 50489062 |
Hyperadrenocorticism | 19.37 | 9.62 | 11 | 115885 | 314 | 50488914 |
Blood parathyroid hormone decreased | 19.09 | 9.62 | 47 | 115849 | 7067 | 50482161 |
Adverse drug reaction | 19.08 | 9.62 | 202 | 115694 | 55020 | 50434208 |
Device issue | 19.07 | 9.62 | 11 | 115885 | 19961 | 50469267 |
Trichostasis spinulosa | 19.03 | 9.62 | 5 | 115891 | 13 | 50489215 |
Anal ulcer | 18.97 | 9.62 | 13 | 115883 | 520 | 50488708 |
Malignant polyp | 18.88 | 9.62 | 9 | 115887 | 177 | 50489051 |
External auditory canal atresia | 18.86 | 9.62 | 7 | 115889 | 71 | 50489157 |
Poisoning | 18.72 | 9.62 | 3 | 115893 | 12426 | 50476802 |
Pruritus | 18.52 | 9.62 | 501 | 115395 | 283067 | 50206161 |
Lethargy | 18.52 | 9.62 | 55 | 115841 | 49377 | 50439851 |
Sinusitis | 18.46 | 9.62 | 277 | 115619 | 170281 | 50318947 |
Malignant melanoma | 18.43 | 9.62 | 58 | 115838 | 10050 | 50479178 |
Gastrointestinal wall thickening | 18.30 | 9.62 | 17 | 115879 | 1059 | 50488169 |
Ill-defined disorder | 18.26 | 9.62 | 64 | 115832 | 54590 | 50434638 |
Transient hypogammaglobulinaemia of infancy | 18.23 | 9.62 | 6 | 115890 | 41 | 50489187 |
Underdose | 18.21 | 9.62 | 12 | 115884 | 20266 | 50468962 |
Peritonitis | 18.17 | 9.62 | 77 | 115819 | 15409 | 50473819 |
Epistaxis | 18.10 | 9.62 | 80 | 115816 | 63874 | 50425354 |
Muscle spasms | 18.04 | 9.62 | 192 | 115704 | 125361 | 50363867 |
Epstein-Barr virus associated lymphoma | 18.04 | 9.62 | 12 | 115884 | 457 | 50488771 |
Vision blurred | 17.94 | 9.62 | 106 | 115790 | 78541 | 50410687 |
Pulmonary oedema | 17.94 | 9.62 | 55 | 115841 | 48883 | 50440345 |
Hypocalcaemia | 17.89 | 9.62 | 21 | 115875 | 26795 | 50462433 |
Rheumatoid lung | 17.85 | 9.62 | 25 | 115871 | 2440 | 50486788 |
Anorectal stenosis | 17.82 | 9.62 | 5 | 115891 | 18 | 50489210 |
Weber tuning fork test abnormal | 17.81 | 9.62 | 7 | 115889 | 84 | 50489144 |
Throat cancer | 17.81 | 9.62 | 12 | 115884 | 467 | 50488761 |
Withdrawal syndrome | 17.80 | 9.62 | 9 | 115887 | 17581 | 50471647 |
Lung abscess | 17.75 | 9.62 | 20 | 115876 | 1566 | 50487662 |
Abortion missed | 17.73 | 9.62 | 20 | 115876 | 1568 | 50487660 |
Transient ischaemic attack | 17.70 | 9.62 | 29 | 115867 | 32181 | 50457047 |
Eye ulcer | 17.66 | 9.62 | 10 | 115886 | 284 | 50488944 |
Hip fracture | 17.63 | 9.62 | 20 | 115876 | 25911 | 50463317 |
Creatinine renal clearance decreased | 17.60 | 9.62 | 3 | 115893 | 11878 | 50477350 |
Pseudoxanthoma elasticum-like syndrome | 17.56 | 9.62 | 4 | 115892 | 4 | 50489224 |
Mitochondrial neurogastrointestinal encephalopathy | 17.56 | 9.62 | 4 | 115892 | 4 | 50489224 |
Meningitis listeria | 17.56 | 9.62 | 12 | 115884 | 478 | 50488750 |
Drug level abnormal | 17.52 | 9.62 | 7 | 115889 | 88 | 50489140 |
Anaplastic large-cell lymphoma | 17.38 | 9.62 | 7 | 115889 | 90 | 50489138 |
Bronchomalacia | 17.37 | 9.62 | 9 | 115887 | 213 | 50489015 |
Bowel movement irregularity | 17.37 | 9.62 | 32 | 115864 | 3936 | 50485292 |
Neutropenia | 17.17 | 9.62 | 237 | 115659 | 147728 | 50341500 |
Abnormal behaviour | 17.16 | 9.62 | 12 | 115884 | 19646 | 50469582 |
Metastases to bone | 17.06 | 9.62 | 10 | 115886 | 17985 | 50471243 |
Pulmonary embolism | 16.94 | 9.62 | 150 | 115746 | 101554 | 50387674 |
Retinal injury | 16.93 | 9.62 | 9 | 115887 | 225 | 50489003 |
Polyhydramnios | 16.89 | 9.62 | 22 | 115874 | 2003 | 50487225 |
Aspergillosis oral | 16.80 | 9.62 | 6 | 115890 | 54 | 50489174 |
Gait disturbance | 16.80 | 9.62 | 242 | 115654 | 149763 | 50339465 |
Proctectomy | 16.80 | 9.62 | 6 | 115890 | 54 | 50489174 |
Carcinoid tumour pulmonary | 16.70 | 9.62 | 11 | 115885 | 412 | 50488816 |
Nightmare | 16.63 | 9.62 | 8 | 115888 | 16078 | 50473150 |
Defaecation urgency | 16.60 | 9.62 | 27 | 115869 | 3006 | 50486222 |
Microsporidia infection | 16.57 | 9.62 | 9 | 115887 | 235 | 50488993 |
Oral lichen planus | 16.55 | 9.62 | 12 | 115884 | 526 | 50488702 |
Stress at work | 16.54 | 9.62 | 16 | 115880 | 1049 | 50488179 |
Enterostomy | 16.44 | 9.62 | 8 | 115888 | 165 | 50489063 |
Pancreatitis acute | 16.41 | 9.62 | 102 | 115794 | 23710 | 50465518 |
Gingival hypertrophy | 16.41 | 9.62 | 18 | 115878 | 1368 | 50487860 |
Metastases to central nervous system | 16.38 | 9.62 | 3 | 115893 | 11279 | 50477949 |
Symptom masked | 16.33 | 9.62 | 13 | 115883 | 656 | 50488572 |
Palatal ulcer | 16.15 | 9.62 | 6 | 115890 | 61 | 50489167 |
Inappropriate antidiuretic hormone secretion | 16.13 | 9.62 | 5 | 115891 | 13138 | 50476090 |
Hyperthyroidism | 16.12 | 9.62 | 4 | 115892 | 12171 | 50477057 |
Anal squamous cell carcinoma | 16.07 | 9.62 | 10 | 115886 | 339 | 50488889 |
Blood glucose decreased | 16.05 | 9.62 | 11 | 115885 | 18200 | 50471028 |
Synovitis | 16.00 | 9.62 | 384 | 115512 | 123481 | 50365747 |
B-cell unclassifiable lymphoma high grade | 15.95 | 9.62 | 4 | 115892 | 8 | 50489220 |
Pulmonary necrosis | 15.94 | 9.62 | 7 | 115889 | 113 | 50489115 |
Faecal calprotectin abnormal | 15.90 | 9.62 | 6 | 115890 | 64 | 50489164 |
Poor venous access | 15.88 | 9.62 | 56 | 115840 | 10284 | 50478944 |
Obstructive airways disorder | 15.85 | 9.62 | 8 | 115888 | 15644 | 50473584 |
Squamous cell carcinoma of the tongue | 15.83 | 9.62 | 10 | 115886 | 348 | 50488880 |
Pain in extremity | 15.82 | 9.62 | 490 | 115406 | 272375 | 50216853 |
American trypanosomiasis | 15.81 | 9.62 | 6 | 115890 | 65 | 50489163 |
Injection site warmth | 15.76 | 9.62 | 6 | 115890 | 13860 | 50475368 |
Exercise tolerance increased | 15.75 | 9.62 | 5 | 115891 | 30 | 50489198 |
Congenital bowing of long bones | 15.73 | 9.62 | 6 | 115890 | 66 | 50489162 |
Patent ductus arteriosus | 15.72 | 9.62 | 30 | 115866 | 3790 | 50485438 |
Cleft lip and palate | 15.71 | 9.62 | 10 | 115886 | 353 | 50488875 |
Muscle spasticity | 15.66 | 9.62 | 10 | 115886 | 17174 | 50472054 |
Complex regional pain syndrome | 15.62 | 9.62 | 21 | 115875 | 1972 | 50487256 |
Knee arthroplasty | 15.62 | 9.62 | 37 | 115859 | 35809 | 50453419 |
Acute respiratory distress syndrome | 15.57 | 9.62 | 92 | 115804 | 21007 | 50468221 |
Memory impairment | 15.55 | 9.62 | 112 | 115784 | 79248 | 50409980 |
Therapy non-responder | 15.52 | 9.62 | 182 | 115714 | 50840 | 50438388 |
Diabetic ketoacidosis | 15.48 | 9.62 | 11 | 115885 | 17861 | 50471367 |
Pleural effusion | 15.46 | 9.62 | 116 | 115780 | 81338 | 50407890 |
Torsade de pointes | 15.45 | 9.62 | 4 | 115892 | 11831 | 50477397 |
Hirsutism | 15.44 | 9.62 | 15 | 115881 | 988 | 50488240 |
Fear | 15.40 | 9.62 | 7 | 115889 | 14542 | 50474686 |
Tonsillar hypertrophy | 15.34 | 9.62 | 14 | 115882 | 852 | 50488376 |
Listeria sepsis | 15.29 | 9.62 | 12 | 115884 | 593 | 50488635 |
Lung infiltration | 15.25 | 9.62 | 66 | 115830 | 13327 | 50475901 |
Oral pain | 15.25 | 9.62 | 21 | 115875 | 25012 | 50464216 |
Irritability | 15.24 | 9.62 | 26 | 115870 | 28400 | 50460828 |
Opportunistic infection | 15.21 | 9.62 | 19 | 115877 | 1659 | 50487569 |
Coronary artery disease | 15.21 | 9.62 | 28 | 115868 | 29698 | 50459530 |
Infertility | 15.15 | 9.62 | 12 | 115884 | 601 | 50488627 |
Acute febrile neutrophilic dermatosis | 15.12 | 9.62 | 24 | 115872 | 2618 | 50486610 |
Injection site pruritus | 15.11 | 9.62 | 45 | 115851 | 40366 | 50448862 |
Superinfection | 15.11 | 9.62 | 21 | 115875 | 2035 | 50487193 |
Deep vein thrombosis | 15.08 | 9.62 | 102 | 115794 | 73202 | 50416026 |
Retinal toxicity | 15.07 | 9.62 | 16 | 115880 | 1172 | 50488056 |
Acne conglobata | 15.06 | 9.62 | 4 | 115892 | 11 | 50489217 |
Anterograde amnesia | 14.99 | 9.62 | 11 | 115885 | 491 | 50488737 |
Anovulatory cycle | 14.86 | 9.62 | 7 | 115889 | 134 | 50489094 |
DNA antibody | 14.85 | 9.62 | 5 | 115891 | 37 | 50489191 |
Mucormycosis | 14.83 | 9.62 | 23 | 115873 | 2460 | 50486768 |
Dry skin | 14.81 | 9.62 | 50 | 115846 | 43141 | 50446087 |
Tonsillitis | 14.81 | 9.62 | 34 | 115862 | 4889 | 50484339 |
Mucosal inflammation | 14.80 | 9.62 | 45 | 115851 | 40097 | 50449131 |
Head injury | 14.78 | 9.62 | 20 | 115876 | 24000 | 50465228 |
Mucous stools | 14.77 | 9.62 | 25 | 115871 | 2877 | 50486351 |
Polyomavirus-associated nephropathy | 14.76 | 9.62 | 18 | 115878 | 1534 | 50487694 |
Lymphoma | 14.75 | 9.62 | 52 | 115844 | 9549 | 50479679 |
Product administration error | 14.74 | 9.62 | 14 | 115882 | 19685 | 50469543 |
Steatorrhoea | 14.73 | 9.62 | 10 | 115886 | 394 | 50488834 |
Aggression | 14.67 | 9.62 | 16 | 115880 | 21100 | 50468128 |
Bulimia nervosa | 14.66 | 9.62 | 10 | 115886 | 397 | 50488831 |
Gastrointestinal motility disorder | 14.52 | 9.62 | 32 | 115864 | 4477 | 50484751 |
Cutaneous leishmaniasis | 14.50 | 9.62 | 6 | 115890 | 83 | 50489145 |
Failed induction of labour | 14.44 | 9.62 | 9 | 115887 | 306 | 50488922 |
Pseudomonas infection | 14.42 | 9.62 | 51 | 115845 | 9379 | 50479849 |
Cervix carcinoma | 14.37 | 9.62 | 23 | 115873 | 2527 | 50486701 |
Tuberous sclerosis complex | 14.37 | 9.62 | 6 | 115890 | 85 | 50489143 |
Cranial sutures widening | 14.34 | 9.62 | 4 | 115892 | 14 | 50489214 |
Gastrointestinal oedema | 14.30 | 9.62 | 15 | 115881 | 1083 | 50488145 |
Hepatitis viral | 14.29 | 9.62 | 10 | 115886 | 414 | 50488814 |
Arthropathy | 14.29 | 9.62 | 265 | 115631 | 157641 | 50331587 |
Legionella infection | 14.21 | 9.62 | 10 | 115886 | 418 | 50488810 |
Pelvic abscess | 14.20 | 9.62 | 17 | 115879 | 1421 | 50487807 |
Contraindicated product administered | 14.19 | 9.62 | 444 | 115452 | 148514 | 50340714 |
Nervousness | 14.19 | 9.62 | 26 | 115870 | 27625 | 50461603 |
Sepsis neonatal | 14.16 | 9.62 | 10 | 115886 | 420 | 50488808 |
Pyometra | 14.06 | 9.62 | 6 | 115890 | 90 | 50489138 |
Anal stenosis | 14.05 | 9.62 | 9 | 115887 | 321 | 50488907 |
Intestinal anastomosis complication | 14.04 | 9.62 | 8 | 115888 | 230 | 50488998 |
Melaena | 14.02 | 9.62 | 25 | 115871 | 26839 | 50462389 |
Abnormal palmar/plantar creases | 14.00 | 9.62 | 5 | 115891 | 45 | 50489183 |
Hypervolaemia | 13.97 | 9.62 | 23 | 115873 | 25476 | 50463752 |
Ureteral neoplasm | 13.93 | 9.62 | 4 | 115892 | 16 | 50489212 |
Asthma | 13.91 | 9.62 | 134 | 115762 | 89203 | 50400025 |
Herpes virus infection | 13.90 | 9.62 | 33 | 115863 | 4848 | 50484380 |
Foetal exposure during delivery | 13.90 | 9.62 | 5 | 115891 | 46 | 50489182 |
Post procedural diarrhoea | 13.89 | 9.62 | 7 | 115889 | 156 | 50489072 |
Atypical mycobacterial infection | 13.84 | 9.62 | 13 | 115883 | 821 | 50488407 |
Intestinal operation | 13.82 | 9.62 | 10 | 115886 | 437 | 50488791 |
Calciphylaxis | 13.79 | 9.62 | 23 | 115873 | 2615 | 50486613 |
Acute myocardial infarction | 13.75 | 9.62 | 29 | 115867 | 29244 | 50459984 |
Lymphocytopenia neonatal | 13.73 | 9.62 | 4 | 115892 | 17 | 50489211 |
Cytomegalovirus mucocutaneous ulcer | 13.73 | 9.62 | 4 | 115892 | 17 | 50489211 |
Upper gastrointestinal haemorrhage | 13.72 | 9.62 | 10 | 115886 | 16025 | 50473203 |
Eye infection fungal | 13.71 | 9.62 | 6 | 115890 | 96 | 50489132 |
Anastomotic stenosis | 13.70 | 9.62 | 8 | 115888 | 241 | 50488987 |
Haematoma | 13.69 | 9.62 | 31 | 115865 | 30479 | 50458749 |
Intestinal polyp | 13.65 | 9.62 | 15 | 115881 | 1142 | 50488086 |
Microscopic polyangiitis | 13.65 | 9.62 | 7 | 115889 | 162 | 50489066 |
Endocarditis noninfective | 13.62 | 9.62 | 5 | 115891 | 49 | 50489179 |
Amniotic cavity infection | 13.59 | 9.62 | 15 | 115881 | 1148 | 50488080 |
Cytomegalovirus chorioretinitis | 13.56 | 9.62 | 17 | 115879 | 1490 | 50487738 |
Pollakiuria | 13.55 | 9.62 | 21 | 115875 | 23830 | 50465398 |
Impetigo | 13.55 | 9.62 | 15 | 115881 | 1152 | 50488076 |
Muscular dystrophy | 13.55 | 9.62 | 4 | 115892 | 18 | 50489210 |
Skin necrosis | 13.50 | 9.62 | 55 | 115841 | 10812 | 50478416 |
Microtia | 13.50 | 9.62 | 9 | 115887 | 344 | 50488884 |
Conjunctivitis allergic | 13.50 | 9.62 | 12 | 115884 | 706 | 50488522 |
Stoma site extravasation | 13.49 | 9.62 | 8 | 115888 | 248 | 50488980 |
Muscle rigidity | 13.47 | 9.62 | 3 | 115893 | 9826 | 50479402 |
Heart rate irregular | 13.39 | 9.62 | 83 | 115813 | 19277 | 50469951 |
Chorioretinitis | 13.39 | 9.62 | 10 | 115886 | 459 | 50488769 |
Fasting | 13.37 | 9.62 | 4 | 115892 | 19 | 50489209 |
Dyspepsia | 13.37 | 9.62 | 107 | 115789 | 73990 | 50415238 |
Dysphonia | 13.35 | 9.62 | 45 | 115851 | 38847 | 50450381 |
Hyperglycaemia | 13.28 | 9.62 | 41 | 115855 | 36364 | 50452864 |
Upper respiratory tract irritation | 13.27 | 9.62 | 5 | 115891 | 53 | 50489175 |
Mediastinal effusion | 13.27 | 9.62 | 5 | 115891 | 53 | 50489175 |
Cafe au lait spots | 13.20 | 9.62 | 4 | 115892 | 20 | 50489208 |
Urinary incontinence | 13.20 | 9.62 | 28 | 115868 | 28180 | 50461048 |
Neoplasm skin | 13.18 | 9.62 | 14 | 115882 | 1026 | 50488202 |
Congenital toxoplasmosis | 13.17 | 9.62 | 3 | 115893 | 3 | 50489225 |
Injection site mass | 13.13 | 9.62 | 10 | 115886 | 15670 | 50473558 |
Glomerulonephritis | 13.10 | 9.62 | 17 | 115879 | 1542 | 50487686 |
Blood potassium increased | 13.05 | 9.62 | 11 | 115885 | 16387 | 50472841 |
Photophobia | 13.05 | 9.62 | 68 | 115828 | 14819 | 50474409 |
Precursor T-lymphoblastic lymphoma/leukaemia | 13.04 | 9.62 | 4 | 115892 | 21 | 50489207 |
Fibroadenoma of breast | 13.03 | 9.62 | 9 | 115887 | 365 | 50488863 |
Migraine | 12.99 | 9.62 | 110 | 115786 | 75170 | 50414058 |
Anaemia macrocytic | 12.96 | 9.62 | 22 | 115874 | 2537 | 50486691 |
Hepatitis cholestatic | 12.95 | 9.62 | 37 | 115859 | 6080 | 50483148 |
Hepatitis E | 12.91 | 9.62 | 15 | 115881 | 1214 | 50488014 |
Device breakage | 12.91 | 9.62 | 3 | 115893 | 9544 | 50479684 |
Ejection fraction decreased | 12.90 | 9.62 | 14 | 115882 | 18506 | 50470722 |
Therapy cessation | 12.87 | 9.62 | 25 | 115871 | 25986 | 50463242 |
Myelitis | 12.86 | 9.62 | 15 | 115881 | 1219 | 50488009 |
Kidney fibrosis | 12.85 | 9.62 | 17 | 115879 | 1572 | 50487656 |
Lung disorder | 12.83 | 9.62 | 158 | 115738 | 44641 | 50444587 |
Anaemia | 12.83 | 9.62 | 461 | 115435 | 251995 | 50237233 |
Drug level above therapeutic | 12.83 | 9.62 | 28 | 115868 | 3892 | 50485336 |
Lacrimation increased | 12.80 | 9.62 | 12 | 115884 | 16980 | 50472248 |
Complications of transplanted kidney | 12.80 | 9.62 | 20 | 115876 | 2153 | 50487075 |
Myopathy | 12.77 | 9.62 | 48 | 115848 | 9091 | 50480137 |
Product storage error | 12.76 | 9.62 | 6 | 115890 | 12218 | 50477010 |
Myasthenia gravis crisis | 12.73 | 9.62 | 9 | 115887 | 379 | 50488849 |
Primary effusion lymphoma | 12.71 | 9.62 | 3 | 115893 | 4 | 50489224 |
Acinetobacter infection | 12.68 | 9.62 | 16 | 115880 | 1411 | 50487817 |
Staphylococcal skin infection | 12.66 | 9.62 | 12 | 115884 | 767 | 50488461 |
Hot flush | 12.65 | 9.62 | 55 | 115841 | 44114 | 50445114 |
Hypoaesthesia | 12.65 | 9.62 | 210 | 115686 | 127047 | 50362181 |
Coloboma | 12.65 | 9.62 | 5 | 115891 | 61 | 50489167 |
Transplant dysfunction | 12.63 | 9.62 | 31 | 115865 | 4653 | 50484575 |
Epidermodysplasia verruciformis | 12.57 | 9.62 | 5 | 115891 | 62 | 50489166 |
Anuria | 12.56 | 9.62 | 5 | 115891 | 11239 | 50477989 |
Threatened labour | 12.55 | 9.62 | 12 | 115884 | 775 | 50488453 |
Neutrophilic dermatosis | 12.54 | 9.62 | 6 | 115890 | 119 | 50489109 |
JC virus infection | 12.54 | 9.62 | 18 | 115878 | 1797 | 50487431 |
Lymphocele | 12.49 | 9.62 | 12 | 115884 | 780 | 50488448 |
Staphylococcal sepsis | 12.48 | 9.62 | 40 | 115856 | 6996 | 50482232 |
Enterococcal sepsis | 12.47 | 9.62 | 15 | 115881 | 1260 | 50487968 |
Necrosis | 12.40 | 9.62 | 31 | 115865 | 4705 | 50484523 |
Food intolerance | 12.37 | 9.62 | 21 | 115875 | 2423 | 50486805 |
Anastomotic complication | 12.36 | 9.62 | 6 | 115890 | 123 | 50489105 |
Disease risk factor | 12.36 | 9.62 | 5 | 115891 | 65 | 50489163 |
Dysarthria | 12.36 | 9.62 | 44 | 115852 | 37359 | 50451869 |
Placental necrosis | 12.33 | 9.62 | 4 | 115892 | 26 | 50489202 |
Skin laceration | 12.31 | 9.62 | 15 | 115881 | 18827 | 50470401 |
Speech disorder | 12.30 | 9.62 | 41 | 115855 | 35507 | 50453721 |
Double stranded DNA antibody positive | 12.28 | 9.62 | 8 | 115888 | 294 | 50488934 |
Intra-abdominal fluid collection | 12.26 | 9.62 | 19 | 115877 | 2031 | 50487197 |
Necrotising retinitis | 12.25 | 9.62 | 8 | 115888 | 295 | 50488933 |
Muir-Torre syndrome | 12.20 | 9.62 | 4 | 115892 | 27 | 50489201 |
Lacrimal haemorrhage | 12.20 | 9.62 | 4 | 115892 | 27 | 50489201 |
Mucosal necrosis | 12.20 | 9.62 | 4 | 115892 | 27 | 50489201 |
Seronegative arthritis | 12.18 | 9.62 | 19 | 115877 | 2042 | 50487186 |
Colostomy | 12.15 | 9.62 | 11 | 115885 | 663 | 50488565 |
Ventricular tachycardia | 12.12 | 9.62 | 11 | 115885 | 15810 | 50473418 |
Encephalitis cytomegalovirus | 12.11 | 9.62 | 10 | 115886 | 532 | 50488696 |
Cavernous sinus thrombosis | 12.06 | 9.62 | 6 | 115890 | 130 | 50489098 |
Ocular toxicity | 12.06 | 9.62 | 10 | 115886 | 535 | 50488693 |
Skin cancer | 12.04 | 9.62 | 48 | 115848 | 9346 | 50479882 |
Sciatica | 11.98 | 9.62 | 87 | 115809 | 21295 | 50467933 |
Gastrointestinal stoma complication | 11.97 | 9.62 | 16 | 115880 | 1494 | 50487734 |
Central nervous system necrosis | 11.94 | 9.62 | 6 | 115890 | 133 | 50489095 |
Electrolyte imbalance | 11.94 | 9.62 | 13 | 115883 | 17156 | 50472072 |
Depressed mood | 11.93 | 9.62 | 39 | 115857 | 33984 | 50455244 |
Bacillary angiomatosis | 11.90 | 9.62 | 5 | 115891 | 72 | 50489156 |
Gastritis haemorrhagic | 11.90 | 9.62 | 15 | 115881 | 1322 | 50487906 |
Abdominal pain lower | 11.89 | 9.62 | 88 | 115808 | 21668 | 50467560 |
Mouth ulceration | 11.88 | 9.62 | 107 | 115789 | 27917 | 50461311 |
Tenderness | 11.85 | 9.62 | 78 | 115818 | 18487 | 50470741 |
Histiocytic necrotising lymphadenitis | 11.83 | 9.62 | 4 | 115892 | 30 | 50489198 |
Varicella zoster pneumonia | 11.83 | 9.62 | 4 | 115892 | 30 | 50489198 |
Cholestasis | 11.82 | 9.62 | 99 | 115797 | 25302 | 50463926 |
Throat irritation | 11.80 | 9.62 | 33 | 115863 | 30206 | 50459022 |
Complications of transplanted lung | 11.78 | 9.62 | 7 | 115889 | 218 | 50489010 |
Meningitis aseptic | 11.75 | 9.62 | 28 | 115868 | 4124 | 50485104 |
Enteritis | 11.72 | 9.62 | 39 | 115857 | 6956 | 50482272 |
Ear pain | 11.69 | 9.62 | 30 | 115866 | 28253 | 50460975 |
DNA antibody positive | 11.68 | 9.62 | 8 | 115888 | 320 | 50488908 |
Ileal ulcer | 11.66 | 9.62 | 9 | 115887 | 434 | 50488794 |
Type 2 diabetes mellitus | 11.65 | 9.62 | 40 | 115856 | 34335 | 50454893 |
Cheilitis granulomatosa | 11.65 | 9.62 | 3 | 115893 | 7 | 50489221 |
Hypergammaglobulinaemia | 11.62 | 9.62 | 9 | 115887 | 436 | 50488792 |
Hallucination, auditory | 11.61 | 9.62 | 5 | 115891 | 10723 | 50478505 |
Gastroenteritis norovirus | 11.60 | 9.62 | 17 | 115879 | 1730 | 50487498 |
Sepsis | 11.57 | 9.62 | 392 | 115504 | 132533 | 50356695 |
Sinus bradycardia | 11.57 | 9.62 | 8 | 115888 | 13175 | 50476053 |
Pyoderma | 11.55 | 9.62 | 7 | 115889 | 226 | 50489002 |
Limb discomfort | 11.55 | 9.62 | 24 | 115872 | 24333 | 50464895 |
Maternal exposure during breast feeding | 11.52 | 9.62 | 24 | 115872 | 3230 | 50485998 |
Infective tenosynovitis | 11.50 | 9.62 | 7 | 115889 | 228 | 50489000 |
Occult blood | 11.48 | 9.62 | 14 | 115882 | 1193 | 50488035 |
Concussion | 11.45 | 9.62 | 41 | 115855 | 7587 | 50481641 |
Perirectal abscess | 11.44 | 9.62 | 12 | 115884 | 867 | 50488361 |
Haemophilus infection | 11.43 | 9.62 | 13 | 115883 | 1028 | 50488200 |
Salmonella bacteraemia | 11.39 | 9.62 | 6 | 115890 | 147 | 50489081 |
Cytopenia | 11.37 | 9.62 | 45 | 115851 | 8730 | 50480498 |
Delusion | 11.32 | 9.62 | 5 | 115891 | 10564 | 50478664 |
Thrombocytopenia | 11.32 | 9.62 | 215 | 115681 | 127458 | 50361770 |
Cholecystitis chronic | 11.30 | 9.62 | 4 | 115892 | 9665 | 50479563 |
Large intestinal ulcer | 11.30 | 9.62 | 23 | 115873 | 3046 | 50486182 |
Respiratory gas exchange disorder | 11.29 | 9.62 | 8 | 115888 | 338 | 50488890 |
Hypoglycaemic seizure | 11.27 | 9.62 | 9 | 115887 | 456 | 50488772 |
Pulmonary congestion | 11.22 | 9.62 | 11 | 115885 | 15236 | 50473992 |
Eye swelling | 11.20 | 9.62 | 18 | 115878 | 20126 | 50469102 |
Cervical incompetence | 11.19 | 9.62 | 10 | 115886 | 592 | 50488636 |
Anger | 11.17 | 9.62 | 6 | 115890 | 11327 | 50477901 |
Myoclonus | 11.16 | 9.62 | 10 | 115886 | 14460 | 50474768 |
Blood immunoglobulin M increased | 11.15 | 9.62 | 7 | 115889 | 241 | 50488987 |
Metastases to liver | 11.14 | 9.62 | 18 | 115878 | 20086 | 50469142 |
Steroid dependence | 11.11 | 9.62 | 8 | 115888 | 347 | 50488881 |
Moraxella infection | 11.09 | 9.62 | 8 | 115888 | 348 | 50488880 |
Renal cell carcinoma | 11.05 | 9.62 | 23 | 115873 | 3094 | 50486134 |
Macular degeneration | 11.03 | 9.62 | 10 | 115886 | 14378 | 50474850 |
Hypophagia | 11.01 | 9.62 | 30 | 115866 | 27698 | 50461530 |
Mental disorder | 11.00 | 9.62 | 21 | 115875 | 21970 | 50467258 |
Haematocrit decreased | 10.99 | 9.62 | 42 | 115854 | 34934 | 50454294 |
Granuloma | 10.89 | 9.62 | 30 | 115866 | 4828 | 50484400 |
Vascular shunt | 10.87 | 9.62 | 3 | 115893 | 10 | 50489218 |
Obliterative bronchiolitis | 10.84 | 9.62 | 17 | 115879 | 1836 | 50487392 |
Proctocolectomy | 10.83 | 9.62 | 4 | 115892 | 40 | 50489188 |
Proctitis ulcerative | 10.80 | 9.62 | 7 | 115889 | 255 | 50488973 |
Intestinal dilatation | 10.80 | 9.62 | 15 | 115881 | 1453 | 50487775 |
Stillbirth | 10.71 | 9.62 | 34 | 115862 | 5918 | 50483310 |
Small intestinal perforation | 10.67 | 9.62 | 14 | 115882 | 1284 | 50487944 |
Tuberculosis of eye | 10.65 | 9.62 | 3 | 115893 | 11 | 50489217 |
Neuropsychiatric lupus | 10.64 | 9.62 | 6 | 115890 | 169 | 50489059 |
Hypocomplementaemia | 10.64 | 9.62 | 6 | 115890 | 169 | 50489059 |
Appendicectomy | 10.62 | 9.62 | 20 | 115876 | 2502 | 50486726 |
Laryngeal stenosis | 10.58 | 9.62 | 11 | 115885 | 786 | 50488442 |
Neuroendocrine carcinoma metastatic | 10.57 | 9.62 | 6 | 115890 | 171 | 50489057 |
Pneumatosis intestinalis | 10.55 | 9.62 | 18 | 115878 | 2085 | 50487143 |
Burning sensation | 10.50 | 9.62 | 61 | 115835 | 45385 | 50443843 |
Feeling jittery | 10.50 | 9.62 | 52 | 115844 | 11108 | 50478120 |
Dermatitis psoriasiform | 10.46 | 9.62 | 16 | 115880 | 1690 | 50487538 |
Renal phospholipidosis | 10.46 | 9.62 | 5 | 115891 | 99 | 50489129 |
Pulmonary venous thrombosis | 10.44 | 9.62 | 3 | 115893 | 12 | 50489216 |
Haemorrhage in pregnancy | 10.44 | 9.62 | 16 | 115880 | 1693 | 50487535 |
Leiomyosarcoma metastatic | 10.44 | 9.62 | 3 | 115893 | 12 | 50489216 |
Small intestinal resection | 10.43 | 9.62 | 8 | 115888 | 382 | 50488846 |
Febrile convulsion | 10.43 | 9.62 | 8 | 115888 | 382 | 50488846 |
Muscle twitching | 10.38 | 9.62 | 12 | 115884 | 15419 | 50473809 |
Anaphylactic shock | 10.30 | 9.62 | 19 | 115877 | 20136 | 50469092 |
Pharyngeal oedema | 10.27 | 9.62 | 9 | 115887 | 13156 | 50476072 |
Rectal cancer | 10.27 | 9.62 | 16 | 115880 | 1718 | 50487510 |
Adjustment disorder with depressed mood | 10.25 | 9.62 | 21 | 115875 | 2793 | 50486435 |
Hodgkin's disease stage II | 10.25 | 9.62 | 3 | 115893 | 13 | 50489215 |
Intestinal fistula infection | 10.25 | 9.62 | 3 | 115893 | 13 | 50489215 |
Hyperparathyroidism secondary | 10.24 | 9.62 | 14 | 115882 | 1336 | 50487892 |
Lentigo maligna | 10.24 | 9.62 | 6 | 115890 | 182 | 50489046 |
Central nervous system vasculitis | 10.24 | 9.62 | 11 | 115885 | 817 | 50488411 |
Cytomegalovirus test positive | 10.23 | 9.62 | 20 | 115876 | 2572 | 50486656 |
Vertigo | 10.22 | 9.62 | 73 | 115823 | 51759 | 50437469 |
Rheumatic disorder | 10.22 | 9.62 | 15 | 115881 | 1528 | 50487700 |
Metastatic malignant melanoma | 10.18 | 9.62 | 13 | 115883 | 1161 | 50488067 |
Amnesia | 10.15 | 9.62 | 56 | 115840 | 42204 | 50447024 |
Infected fistula | 10.15 | 9.62 | 5 | 115891 | 106 | 50489122 |
Evans syndrome | 10.15 | 9.62 | 6 | 115890 | 185 | 50489043 |
Panic attack | 10.09 | 9.62 | 18 | 115878 | 19324 | 50469904 |
Febrile infection | 10.09 | 9.62 | 13 | 115883 | 1171 | 50488057 |
Incorrect route of product administration | 10.08 | 9.62 | 17 | 115879 | 18649 | 50470579 |
Mycetoma mycotic | 10.07 | 9.62 | 3 | 115893 | 14 | 50489214 |
Ubiquinone decreased | 10.07 | 9.62 | 3 | 115893 | 14 | 50489214 |
Affect lability | 10.05 | 9.62 | 4 | 115892 | 8994 | 50480234 |
Hidradenitis | 10.03 | 9.62 | 17 | 115879 | 1958 | 50487270 |
Photosensitivity reaction | 9.98 | 9.62 | 57 | 115839 | 12854 | 50476374 |
Idiopathic pulmonary fibrosis | 9.98 | 9.62 | 13 | 115883 | 1184 | 50488044 |
Bronchostenosis | 9.98 | 9.62 | 8 | 115888 | 408 | 50488820 |
Polymyositis | 9.95 | 9.62 | 15 | 115881 | 1565 | 50487663 |
Angina pectoris | 9.91 | 9.62 | 29 | 115867 | 26159 | 50463069 |
Ischaemic nephropathy | 9.90 | 9.62 | 3 | 115893 | 15 | 50489213 |
Spinal cord disorder | 9.89 | 9.62 | 13 | 115883 | 1194 | 50488034 |
Blood sodium decreased | 9.89 | 9.62 | 21 | 115875 | 21126 | 50468102 |
Renal colic | 9.87 | 9.62 | 13 | 115883 | 1196 | 50488032 |
Rash pustular | 9.87 | 9.62 | 35 | 115861 | 6446 | 50482782 |
Nail disorder | 9.77 | 9.62 | 5 | 115891 | 9703 | 50479525 |
Pouchitis | 9.76 | 9.62 | 8 | 115888 | 421 | 50488807 |
Campylobacter infection | 9.76 | 9.62 | 10 | 115886 | 703 | 50488525 |
Portal venous gas | 9.75 | 9.62 | 4 | 115892 | 54 | 50489174 |
Retinitis viral | 9.74 | 9.62 | 3 | 115893 | 16 | 50489212 |
Infective aortitis | 9.74 | 9.62 | 3 | 115893 | 16 | 50489212 |
Immune-mediated myositis | 9.74 | 9.62 | 12 | 115884 | 1033 | 50488195 |
Infective pulmonary exacerbation of cystic fibrosis | 9.72 | 9.62 | 3 | 115893 | 7906 | 50481322 |
Iron deficiency anaemia | 9.72 | 9.62 | 69 | 115827 | 16765 | 50472463 |
Scedosporium infection | 9.71 | 9.62 | 8 | 115888 | 424 | 50488804 |
Breast adenoma | 9.69 | 9.62 | 4 | 115892 | 55 | 50489173 |
Mental impairment | 9.68 | 9.62 | 8 | 115888 | 12036 | 50477192 |
Drug specific antibody | 9.66 | 9.62 | 16 | 115880 | 1809 | 50487419 |
Butterfly rash | 9.65 | 9.62 | 13 | 115883 | 1223 | 50488005 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Colitis ulcerative | 388.86 | 10.71 | 278 | 64508 | 12491 | 29497250 |
Drug ineffective | 355.68 | 10.71 | 1651 | 63135 | 361519 | 29148222 |
Off label use | 352.65 | 10.71 | 1444 | 63342 | 299356 | 29210385 |
Drug eruption | 272.67 | 10.71 | 253 | 64533 | 16488 | 29493253 |
Hepatosplenic T-cell lymphoma | 260.08 | 10.71 | 76 | 64710 | 346 | 29509395 |
Death | 257.02 | 10.71 | 224 | 64562 | 341860 | 29167881 |
Post transplant lymphoproliferative disorder | 218.18 | 10.71 | 141 | 64645 | 5352 | 29504389 |
Intestinal stenosis | 213.24 | 10.71 | 97 | 64689 | 1791 | 29507950 |
Fistula | 201.86 | 10.71 | 131 | 64655 | 5008 | 29504733 |
Nodular regenerative hyperplasia | 196.88 | 10.71 | 69 | 64717 | 614 | 29509127 |
Cytomegalovirus infection | 194.51 | 10.71 | 247 | 64539 | 22968 | 29486773 |
Epstein-Barr virus infection | 189.62 | 10.71 | 139 | 64647 | 6490 | 29503251 |
Frequent bowel movements | 170.82 | 10.71 | 150 | 64636 | 9089 | 29500652 |
Anal abscess | 170.64 | 10.71 | 119 | 64667 | 5132 | 29504609 |
Hypersensitivity | 166.68 | 10.71 | 362 | 64424 | 52541 | 29457200 |
Lymphoproliferative disorder | 166.57 | 10.71 | 90 | 64696 | 2437 | 29507304 |
Intentional product use issue | 166.13 | 10.71 | 318 | 64468 | 42180 | 29467561 |
Product use issue | 162.05 | 10.71 | 352 | 64434 | 51092 | 29458649 |
Drug abuse | 160.02 | 10.71 | 3 | 64783 | 79880 | 29429861 |
Diffuse large B-cell lymphoma | 158.18 | 10.71 | 122 | 64664 | 6154 | 29503587 |
Completed suicide | 149.57 | 10.71 | 13 | 64773 | 90233 | 29419508 |
Hepatic function abnormal | 148.83 | 10.71 | 290 | 64496 | 38969 | 29470772 |
Ileal stenosis | 135.20 | 10.71 | 62 | 64724 | 1167 | 29508574 |
Therapeutic product effect decreased | 133.52 | 10.71 | 235 | 64551 | 29216 | 29480525 |
Intestinal obstruction | 127.73 | 10.71 | 183 | 64603 | 19094 | 29490647 |
Anal fistula | 124.60 | 10.71 | 90 | 64696 | 4105 | 29505636 |
Disseminated tuberculosis | 124.10 | 10.71 | 68 | 64718 | 1894 | 29507847 |
Fall | 119.78 | 10.71 | 127 | 64659 | 177051 | 29332690 |
Febrile neutropenia | 119.76 | 10.71 | 48 | 64738 | 112192 | 29397549 |
Cytomegalovirus colitis | 117.25 | 10.71 | 71 | 64715 | 2398 | 29507343 |
Crohn's disease | 116.45 | 10.71 | 76 | 64710 | 2933 | 29506808 |
Squamous cell carcinoma | 113.86 | 10.71 | 126 | 64660 | 10125 | 29499616 |
Hypotension | 112.69 | 10.71 | 157 | 64629 | 194197 | 29315544 |
Disease recurrence | 111.24 | 10.71 | 155 | 64631 | 15759 | 29493982 |
Condition aggravated | 110.99 | 10.71 | 621 | 64165 | 145674 | 29364067 |
Haemophagocytic lymphohistiocytosis | 109.64 | 10.71 | 125 | 64661 | 10379 | 29499362 |
Transplant rejection | 108.88 | 10.71 | 117 | 64669 | 9095 | 29500646 |
Product use in unapproved indication | 106.39 | 10.71 | 424 | 64362 | 86451 | 29423290 |
Treatment failure | 104.23 | 10.71 | 242 | 64544 | 36697 | 29473044 |
Infusion related reaction | 103.12 | 10.71 | 268 | 64518 | 43618 | 29466123 |
Toxicity to various agents | 102.94 | 10.71 | 138 | 64648 | 173523 | 29336218 |
Urticaria | 99.24 | 10.71 | 304 | 64482 | 54356 | 29455385 |
Stomatitis | 99.13 | 10.71 | 238 | 64548 | 36875 | 29472866 |
Premature baby | 98.65 | 10.71 | 153 | 64633 | 17127 | 29492614 |
Malignant neoplasm progression | 98.07 | 10.71 | 21 | 64765 | 73838 | 29435903 |
JC virus infection | 96.44 | 10.71 | 57 | 64729 | 1840 | 29507901 |
Large intestinal stenosis | 96.11 | 10.71 | 51 | 64735 | 1330 | 29508411 |
Pulmonary tuberculosis | 96.10 | 10.71 | 78 | 64708 | 4237 | 29505504 |
Blood pressure fluctuation | 94.40 | 10.71 | 162 | 64624 | 19732 | 29490009 |
Inappropriate schedule of product administration | 93.84 | 10.71 | 261 | 64525 | 44211 | 29465530 |
Acute febrile neutrophilic dermatosis | 93.13 | 10.71 | 46 | 64740 | 1028 | 29508713 |
Progressive multifocal leukoencephalopathy | 93.11 | 10.71 | 105 | 64681 | 8614 | 29501127 |
Leukopenia | 92.84 | 10.71 | 299 | 64487 | 54904 | 29454837 |
Drug level below therapeutic | 92.59 | 10.71 | 76 | 64710 | 4195 | 29505546 |
Pneumocystis jirovecii pneumonia | 92.23 | 10.71 | 146 | 64640 | 16633 | 29493108 |
Pancytopenia | 91.66 | 10.71 | 393 | 64393 | 82775 | 29426966 |
Cushingoid | 90.50 | 10.71 | 60 | 64726 | 2378 | 29507363 |
Faecal calprotectin increased | 90.26 | 10.71 | 51 | 64735 | 1510 | 29508231 |
Dizziness | 88.77 | 10.71 | 176 | 64610 | 189508 | 29320233 |
Intestinal fistula | 86.55 | 10.71 | 41 | 64745 | 833 | 29508908 |
Epstein-Barr virus associated lymphoproliferative disorder | 85.17 | 10.71 | 51 | 64735 | 1687 | 29508054 |
Myocardial infarction | 85.12 | 10.71 | 70 | 64716 | 110226 | 29399515 |
Somnolence | 81.09 | 10.71 | 53 | 64733 | 93902 | 29415839 |
Drug level decreased | 80.34 | 10.71 | 83 | 64703 | 6164 | 29503577 |
Drug specific antibody present | 78.47 | 10.71 | 56 | 64730 | 2505 | 29507236 |
Basal cell carcinoma | 78.00 | 10.71 | 136 | 64650 | 16774 | 29492967 |
Kidney transplant rejection | 77.61 | 10.71 | 86 | 64700 | 6919 | 29502822 |
Erythema nodosum | 77.51 | 10.71 | 39 | 64747 | 908 | 29508833 |
Tuberculosis | 77.42 | 10.71 | 87 | 64699 | 7109 | 29502632 |
Intestinal resection | 77.14 | 10.71 | 45 | 64741 | 1417 | 29508324 |
Colitis | 74.59 | 10.71 | 192 | 64594 | 31056 | 29478685 |
Epistaxis | 74.55 | 10.71 | 266 | 64520 | 51438 | 29458303 |
Acute kidney injury | 74.38 | 10.71 | 314 | 64472 | 264953 | 29244788 |
Human herpesvirus 8 infection | 72.62 | 10.71 | 36 | 64750 | 811 | 29508930 |
Cardiac failure congestive | 71.99 | 10.71 | 39 | 64747 | 76542 | 29433199 |
Small intestinal stenosis | 71.07 | 10.71 | 29 | 64757 | 405 | 29509336 |
Squamous cell carcinoma of skin | 70.21 | 10.71 | 95 | 64691 | 9391 | 29500350 |
Diarrhoea haemorrhagic | 70.11 | 10.71 | 75 | 64711 | 5799 | 29503942 |
Abdominal pain | 67.88 | 10.71 | 518 | 64268 | 134839 | 29374902 |
Coombs positive haemolytic anaemia | 67.57 | 10.71 | 33 | 64753 | 719 | 29509022 |
Dyspnoea | 67.28 | 10.71 | 430 | 64356 | 326302 | 29183439 |
Pemphigus | 67.10 | 10.71 | 38 | 64748 | 1130 | 29508611 |
Gastrointestinal inflammation | 66.20 | 10.71 | 54 | 64732 | 2954 | 29506787 |
Epidermodysplasia verruciformis | 65.63 | 10.71 | 20 | 64766 | 108 | 29509633 |
Intentional overdose | 65.32 | 10.71 | 5 | 64781 | 38523 | 29471218 |
Abscess | 65.13 | 10.71 | 93 | 64693 | 9669 | 29500072 |
Confusional state | 64.76 | 10.71 | 113 | 64673 | 127764 | 29381977 |
Bradycardia | 63.79 | 10.71 | 32 | 64754 | 65597 | 29444144 |
Clear cell renal cell carcinoma | 63.70 | 10.71 | 35 | 64751 | 980 | 29508761 |
Nocardiosis | 62.41 | 10.71 | 54 | 64732 | 3206 | 29506535 |
Cytomegalovirus viraemia | 62.24 | 10.71 | 73 | 64713 | 6247 | 29503494 |
T-cell lymphoma | 61.93 | 10.71 | 33 | 64753 | 868 | 29508873 |
Muscle spasms | 61.53 | 10.71 | 294 | 64492 | 64788 | 29444953 |
Atrial fibrillation | 61.46 | 10.71 | 85 | 64701 | 105561 | 29404180 |
Immunosuppression | 60.47 | 10.71 | 66 | 64720 | 5220 | 29504521 |
Therapeutic response shortened | 60.43 | 10.71 | 63 | 64723 | 4728 | 29505013 |
Meningitis listeria | 60.33 | 10.71 | 25 | 64761 | 364 | 29509377 |
Herpes zoster | 60.07 | 10.71 | 173 | 64613 | 29879 | 29479862 |
Night sweats | 59.85 | 10.71 | 113 | 64673 | 14819 | 29494922 |
Lung transplant rejection | 59.79 | 10.71 | 30 | 64756 | 694 | 29509047 |
Product dose omission issue | 59.70 | 10.71 | 74 | 64712 | 96309 | 29413432 |
Non-cirrhotic portal hypertension | 59.29 | 10.71 | 22 | 64764 | 234 | 29509507 |
B-cell lymphoma | 58.86 | 10.71 | 56 | 64730 | 3762 | 29505979 |
Lymphopenia | 58.75 | 10.71 | 106 | 64680 | 13427 | 29496314 |
Lymphadenitis | 58.33 | 10.71 | 39 | 64747 | 1568 | 29508173 |
Colectomy | 58.25 | 10.71 | 38 | 64748 | 1465 | 29508276 |
Renal cell carcinoma | 57.89 | 10.71 | 61 | 64725 | 4635 | 29505106 |
Hand deformity | 57.18 | 10.71 | 43 | 64743 | 2087 | 29507654 |
Abdominal adhesions | 57.16 | 10.71 | 35 | 64751 | 1206 | 29508535 |
Drug intolerance | 55.87 | 10.71 | 232 | 64554 | 48147 | 29461594 |
Histoplasmosis disseminated | 54.58 | 10.71 | 33 | 64753 | 1111 | 29508630 |
Hyponatraemia | 54.57 | 10.71 | 41 | 64745 | 67592 | 29442149 |
Overdose | 54.07 | 10.71 | 57 | 64729 | 79762 | 29429979 |
Epstein-Barr virus test positive | 54.01 | 10.71 | 25 | 64761 | 481 | 29509260 |
Epstein-Barr virus associated lymphoma | 53.76 | 10.71 | 26 | 64760 | 554 | 29509187 |
Cardiac arrest | 53.75 | 10.71 | 65 | 64721 | 85526 | 29424215 |
Dehydration | 53.14 | 10.71 | 107 | 64679 | 114641 | 29395100 |
Kaposi's sarcoma | 52.11 | 10.71 | 29 | 64757 | 833 | 29508908 |
Heart transplant rejection | 51.84 | 10.71 | 32 | 64754 | 1119 | 29508622 |
Cytomegalovirus enteritis | 51.13 | 10.71 | 23 | 64763 | 413 | 29509328 |
Intestinal perforation | 50.98 | 10.71 | 75 | 64711 | 8011 | 29501730 |
Haematochezia | 50.52 | 10.71 | 187 | 64599 | 36796 | 29472945 |
Transplant dysfunction | 50.48 | 10.71 | 41 | 64745 | 2229 | 29507512 |
Cardio-respiratory arrest | 50.18 | 10.71 | 24 | 64762 | 50577 | 29459164 |
Neuropathy peripheral | 48.92 | 10.71 | 50 | 64736 | 70977 | 29438764 |
Small intestinal obstruction | 48.86 | 10.71 | 96 | 64690 | 12965 | 29496776 |
Defaecation urgency | 48.49 | 10.71 | 36 | 64750 | 1713 | 29508028 |
Decreased appetite | 48.49 | 10.71 | 160 | 64626 | 145182 | 29364559 |
Portal hypertension | 47.89 | 10.71 | 48 | 64738 | 3438 | 29506303 |
Pneumonia aspiration | 47.62 | 10.71 | 11 | 64775 | 36726 | 29473015 |
Chronic allograft nephropathy | 47.57 | 10.71 | 30 | 64756 | 1090 | 29508651 |
Syncope | 46.78 | 10.71 | 66 | 64720 | 81305 | 29428436 |
Lymphoma | 46.57 | 10.71 | 80 | 64706 | 9748 | 29499993 |
Polyhydramnios | 45.84 | 10.71 | 18 | 64768 | 226 | 29509515 |
Rebound effect | 45.83 | 10.71 | 37 | 64749 | 1994 | 29507747 |
Anal fissure | 44.84 | 10.71 | 42 | 64744 | 2766 | 29506975 |
Blood glucose increased | 44.77 | 10.71 | 38 | 64748 | 58946 | 29450795 |
Loss of consciousness | 43.63 | 10.71 | 59 | 64727 | 73997 | 29435744 |
Pain in extremity | 43.26 | 10.71 | 400 | 64386 | 110033 | 29399708 |
Weight decreased | 42.83 | 10.71 | 512 | 64274 | 150393 | 29359348 |
Peliosis hepatis | 42.71 | 10.71 | 12 | 64774 | 46 | 29509695 |
Acute myocardial infarction | 42.20 | 10.71 | 27 | 64759 | 48411 | 29461330 |
Aggression | 41.62 | 10.71 | 13 | 64773 | 35528 | 29474213 |
Lymphocytopenia neonatal | 41.55 | 10.71 | 9 | 64777 | 6 | 29509735 |
Aspergillus infection | 41.07 | 10.71 | 79 | 64707 | 10502 | 29499239 |
Extrapulmonary tuberculosis | 40.96 | 10.71 | 13 | 64773 | 82 | 29509659 |
Clostridium difficile infection | 40.40 | 10.71 | 101 | 64685 | 16040 | 29493701 |
Delirium | 40.12 | 10.71 | 18 | 64768 | 39379 | 29470362 |
Histoplasmosis | 40.06 | 10.71 | 29 | 64757 | 1327 | 29508414 |
Rash | 39.87 | 10.71 | 248 | 64538 | 189571 | 29320170 |
Rheumatoid factor negative | 39.75 | 10.71 | 24 | 64762 | 806 | 29508935 |
Chronic obstructive pulmonary disease | 39.74 | 10.71 | 20 | 64766 | 40935 | 29468806 |
Hypoglycaemia | 39.39 | 10.71 | 29 | 64757 | 48317 | 29461424 |
Cholangitis sclerosing | 38.98 | 10.71 | 26 | 64760 | 1041 | 29508700 |
Insomnia | 38.37 | 10.71 | 86 | 64700 | 88675 | 29421066 |
Neuroendocrine carcinoma of the skin | 37.87 | 10.71 | 21 | 64765 | 599 | 29509142 |
Plasma cell myeloma | 37.73 | 10.71 | 17 | 64769 | 37098 | 29472643 |
Arthralgia | 37.56 | 10.71 | 469 | 64317 | 139148 | 29370593 |
Therapeutic product effect incomplete | 37.44 | 10.71 | 178 | 64608 | 39127 | 29470614 |
Bronchopulmonary aspergillosis | 37.15 | 10.71 | 83 | 64703 | 12261 | 29497480 |
International normalised ratio increased | 36.96 | 10.71 | 26 | 64760 | 44346 | 29465395 |
Candida infection | 36.78 | 10.71 | 94 | 64692 | 15131 | 29494610 |
Cutaneous T-cell lymphoma | 36.71 | 10.71 | 27 | 64759 | 1266 | 29508475 |
Rectal abscess | 36.68 | 10.71 | 24 | 64762 | 930 | 29508811 |
Abnormal behaviour | 36.52 | 10.71 | 4 | 64782 | 23123 | 29486618 |
Abscess intestinal | 36.40 | 10.71 | 28 | 64758 | 1406 | 29508335 |
Infection reactivation | 36.17 | 10.71 | 25 | 64761 | 1062 | 29508679 |
Rectal fissure | 36.15 | 10.71 | 16 | 64770 | 276 | 29509465 |
Mycobacterial infection | 36.04 | 10.71 | 31 | 64755 | 1825 | 29507916 |
Varicella zoster virus infection | 35.82 | 10.71 | 28 | 64758 | 1440 | 29508301 |
Coma | 35.74 | 10.71 | 21 | 64765 | 39429 | 29470312 |
Pancreatitis | 35.60 | 10.71 | 160 | 64626 | 34354 | 29475387 |
Cerebrovascular accident | 35.34 | 10.71 | 72 | 64714 | 76839 | 29432902 |
Mycoplasma infection | 35.33 | 10.71 | 16 | 64770 | 292 | 29509449 |
Respiratory arrest | 34.98 | 10.71 | 7 | 64779 | 25826 | 29483915 |
Lymphocyte count abnormal | 34.94 | 10.71 | 20 | 64766 | 607 | 29509134 |
Electrocardiogram QT prolonged | 34.53 | 10.71 | 18 | 64768 | 36119 | 29473622 |
Pyrexia | 34.34 | 10.71 | 848 | 63938 | 286774 | 29222967 |
Wrong technique in product usage process | 34.20 | 10.71 | 13 | 64773 | 31415 | 29478326 |
Inflammatory bowel disease | 33.93 | 10.71 | 33 | 64753 | 2278 | 29507463 |
Oedema peripheral | 33.82 | 10.71 | 115 | 64671 | 103442 | 29406299 |
Asthenia | 33.43 | 10.71 | 306 | 64480 | 214944 | 29294797 |
Cardiac failure | 33.32 | 10.71 | 78 | 64708 | 79209 | 29430532 |
Enterocutaneous fistula | 33.25 | 10.71 | 21 | 64765 | 765 | 29508976 |
Visceral leishmaniasis | 32.95 | 10.71 | 18 | 64768 | 498 | 29509243 |
Low birth weight baby | 32.91 | 10.71 | 55 | 64731 | 6553 | 29503188 |
Actinic keratosis | 32.82 | 10.71 | 41 | 64745 | 3745 | 29505996 |
Hypokalaemia | 32.71 | 10.71 | 37 | 64749 | 50166 | 29459575 |
Lupus-like syndrome | 32.65 | 10.71 | 32 | 64754 | 2230 | 29507511 |
Gastrointestinal disorder | 32.61 | 10.71 | 137 | 64649 | 28569 | 29481172 |
Hallucination | 32.49 | 10.71 | 30 | 64756 | 44682 | 29465059 |
Intestinal fibrosis | 32.41 | 10.71 | 11 | 64775 | 88 | 29509653 |
Drug level above therapeutic | 32.20 | 10.71 | 38 | 64748 | 3272 | 29506469 |
Red blood cell sedimentation rate abnormal | 32.17 | 10.71 | 32 | 64754 | 2271 | 29507470 |
Gastrointestinal haemorrhage | 32.03 | 10.71 | 80 | 64706 | 79453 | 29430288 |
Bone marrow failure | 31.96 | 10.71 | 132 | 64654 | 27317 | 29482424 |
Vasculitis | 31.77 | 10.71 | 60 | 64726 | 7868 | 29501873 |
Herpes simplex | 31.76 | 10.71 | 46 | 64740 | 4844 | 29504897 |
Foetal growth restriction | 31.41 | 10.71 | 40 | 64746 | 3726 | 29506015 |
Splenomegaly | 31.06 | 10.71 | 81 | 64705 | 13198 | 29496543 |
Obliterative bronchiolitis | 31.00 | 10.71 | 23 | 64763 | 1093 | 29508648 |
Abdominal abscess | 30.92 | 10.71 | 40 | 64746 | 3784 | 29505957 |
Orthostatic hypotension | 30.92 | 10.71 | 6 | 64780 | 22623 | 29487118 |
Neutrophil count decreased | 30.75 | 10.71 | 30 | 64756 | 43537 | 29466204 |
Therapeutic response decreased | 30.50 | 10.71 | 121 | 64665 | 24590 | 29485151 |
Urinary retention | 30.31 | 10.71 | 16 | 64770 | 31882 | 29477859 |
Cystitis escherichia | 29.98 | 10.71 | 12 | 64774 | 159 | 29509582 |
Anxiety | 29.81 | 10.71 | 92 | 64694 | 85273 | 29424468 |
Fistula discharge | 29.75 | 10.71 | 16 | 64770 | 429 | 29509312 |
Rectal haemorrhage | 29.72 | 10.71 | 152 | 64634 | 34397 | 29475344 |
Gastrointestinal fistula | 29.70 | 10.71 | 15 | 64771 | 352 | 29509389 |
Fatigue | 29.39 | 10.71 | 503 | 64283 | 316318 | 29193423 |
Agitation | 29.09 | 10.71 | 42 | 64744 | 51262 | 29458479 |
Balance disorder | 29.07 | 10.71 | 22 | 64764 | 36148 | 29473593 |
Depressed level of consciousness | 29.02 | 10.71 | 23 | 64763 | 36919 | 29472822 |
Nephropathy toxic | 28.72 | 10.71 | 69 | 64717 | 10687 | 29499054 |
Heart rate irregular | 28.65 | 10.71 | 78 | 64708 | 13039 | 29496702 |
Drug resistance | 28.64 | 10.71 | 108 | 64678 | 21432 | 29488309 |
Cow pox | 28.61 | 10.71 | 8 | 64778 | 30 | 29509711 |
Gastrointestinal lymphoma | 28.61 | 10.71 | 8 | 64778 | 30 | 29509711 |
Myopathy | 28.59 | 10.71 | 68 | 64718 | 10465 | 29499276 |
Lung neoplasm | 28.44 | 10.71 | 41 | 64745 | 4299 | 29505442 |
Complications of transplanted kidney | 28.35 | 10.71 | 39 | 64747 | 3915 | 29505826 |
Granulomatosis with polyangiitis | 28.19 | 10.71 | 20 | 64766 | 886 | 29508855 |
Unresponsive to stimuli | 28.00 | 10.71 | 10 | 64776 | 25116 | 29484625 |
Enteritis | 27.96 | 10.71 | 52 | 64734 | 6739 | 29503002 |
Angina pectoris | 27.93 | 10.71 | 13 | 64773 | 27837 | 29481904 |
Gastrointestinal wall thickening | 27.90 | 10.71 | 22 | 64764 | 1146 | 29508595 |
Accidental overdose | 27.89 | 10.71 | 3 | 64783 | 17590 | 29492151 |
Foetal exposure during pregnancy | 27.75 | 10.71 | 147 | 64639 | 33720 | 29476021 |
Hospitalisation | 27.73 | 10.71 | 36 | 64750 | 45952 | 29463789 |
Herpes zoster meningoencephalitis | 27.72 | 10.71 | 13 | 64773 | 258 | 29509483 |
Limb deformity | 27.71 | 10.71 | 16 | 64770 | 494 | 29509247 |
Mycobacterium chelonae infection | 27.63 | 10.71 | 17 | 64769 | 591 | 29509150 |
White blood cell count decreased | 27.60 | 10.71 | 92 | 64694 | 83270 | 29426471 |
Contusion | 27.54 | 10.71 | 17 | 64769 | 31078 | 29478663 |
Pouchitis | 27.50 | 10.71 | 17 | 64769 | 596 | 29509145 |
Disease progression | 27.40 | 10.71 | 90 | 64696 | 81826 | 29427915 |
Scleroderma | 27.32 | 10.71 | 23 | 64763 | 1315 | 29508426 |
Chronic gastrointestinal bleeding | 27.09 | 10.71 | 13 | 64773 | 272 | 29509469 |
Dysgeusia | 27.08 | 10.71 | 8 | 64778 | 22666 | 29487075 |
Listeria sepsis | 27.06 | 10.71 | 11 | 64775 | 152 | 29509589 |
Cytomegalovirus infection reactivation | 26.91 | 10.71 | 35 | 64751 | 3329 | 29506412 |
Intestinal anastomosis | 26.91 | 10.71 | 12 | 64774 | 211 | 29509530 |
Liver transplant rejection | 26.78 | 10.71 | 27 | 64759 | 1947 | 29507794 |
Seizure | 26.75 | 10.71 | 109 | 64677 | 93014 | 29416727 |
Hepatitis | 26.64 | 10.71 | 103 | 64683 | 20680 | 29489061 |
Papilloma viral infection | 26.58 | 10.71 | 15 | 64771 | 443 | 29509298 |
Plasmablastic lymphoma | 26.50 | 10.71 | 12 | 64774 | 219 | 29509522 |
Legionella infection | 26.49 | 10.71 | 15 | 64771 | 446 | 29509295 |
Acquired gene mutation | 26.46 | 10.71 | 22 | 64764 | 1236 | 29508505 |
Gait disturbance | 26.36 | 10.71 | 78 | 64708 | 73271 | 29436470 |
Disorientation | 26.33 | 10.71 | 16 | 64770 | 29499 | 29480242 |
Diffuse large B-cell lymphoma stage IV | 26.16 | 10.71 | 12 | 64774 | 226 | 29509515 |
Eosinophilic bronchitis | 26.13 | 10.71 | 11 | 64775 | 167 | 29509574 |
Tachycardia | 26.02 | 10.71 | 77 | 64709 | 72333 | 29437408 |
Malignant melanoma | 26.02 | 10.71 | 52 | 64734 | 7109 | 29502632 |
Congenital cytomegalovirus infection | 25.74 | 10.71 | 7 | 64779 | 23 | 29509718 |
Myasthenia gravis crisis | 25.61 | 10.71 | 15 | 64771 | 476 | 29509265 |
Myasthenic syndrome | 25.45 | 10.71 | 14 | 64772 | 393 | 29509348 |
Ileostomy | 25.44 | 10.71 | 15 | 64771 | 482 | 29509259 |
Complications of transplanted lung | 25.44 | 10.71 | 11 | 64775 | 179 | 29509562 |
Graft versus host disease in lung | 25.32 | 10.71 | 15 | 64771 | 486 | 29509255 |
Squamous cell carcinoma of the tongue | 25.14 | 10.71 | 12 | 64774 | 248 | 29509493 |
Constipation | 25.05 | 10.71 | 147 | 64639 | 114013 | 29395728 |
Strongyloidiasis | 24.95 | 10.71 | 28 | 64758 | 2284 | 29507457 |
Molluscum contagiosum | 24.76 | 10.71 | 12 | 64774 | 257 | 29509484 |
Transient ischaemic attack | 24.70 | 10.71 | 10 | 64776 | 23260 | 29486481 |
Irritability | 24.37 | 10.71 | 9 | 64777 | 22143 | 29487598 |
Periumbilical abscess | 24.37 | 10.71 | 8 | 64778 | 57 | 29509684 |
Hepatosplenomegaly | 24.19 | 10.71 | 35 | 64751 | 3682 | 29506059 |
Dyskinesia | 24.10 | 10.71 | 7 | 64779 | 20054 | 29489687 |
Intestinal mass | 24.08 | 10.71 | 14 | 64772 | 438 | 29509303 |
Epstein Barr virus positive mucocutaneous ulcer | 23.82 | 10.71 | 12 | 64774 | 280 | 29509461 |
Body temperature fluctuation | 23.76 | 10.71 | 22 | 64764 | 1428 | 29508313 |
Peritoneal abscess | 23.68 | 10.71 | 8 | 64778 | 63 | 29509678 |
Meningitis cryptococcal | 23.64 | 10.71 | 26 | 64760 | 2074 | 29507667 |
Steroid dependence | 23.59 | 10.71 | 12 | 64774 | 286 | 29509455 |
Varicella | 23.59 | 10.71 | 22 | 64764 | 1441 | 29508300 |
Hypocalcaemia | 23.41 | 10.71 | 8 | 64778 | 20657 | 29489084 |
Phaeohyphomycosis | 23.38 | 10.71 | 17 | 64769 | 783 | 29508958 |
Therapeutic reaction time decreased | 23.37 | 10.71 | 16 | 64770 | 669 | 29509072 |
Osteonecrosis of jaw | 23.37 | 10.71 | 4 | 64782 | 16506 | 29493235 |
Tonsil cancer | 23.24 | 10.71 | 18 | 64768 | 913 | 29508828 |
Non-Hodgkin's lymphoma | 23.16 | 10.71 | 22 | 64764 | 1475 | 29508266 |
Chronic myeloid leukaemia | 22.99 | 10.71 | 25 | 64761 | 1969 | 29507772 |
Hydrops foetalis | 22.98 | 10.71 | 11 | 64775 | 229 | 29509512 |
Lung abscess | 22.75 | 10.71 | 27 | 64759 | 2339 | 29507402 |
Lupus nephritis | 22.68 | 10.71 | 11 | 64775 | 236 | 29509505 |
Eosinophilic granulomatosis with polyangiitis | 22.65 | 10.71 | 21 | 64765 | 1365 | 29508376 |
Systemic lupus erythematosus | 22.58 | 10.71 | 28 | 64758 | 2538 | 29507203 |
Bone erosion | 22.52 | 10.71 | 29 | 64757 | 2731 | 29507010 |
C-reactive protein increased | 22.45 | 10.71 | 170 | 64616 | 44093 | 29465648 |
Intestinal anastomosis complication | 22.30 | 10.71 | 9 | 64777 | 122 | 29509619 |
Product prescribing error | 22.10 | 10.71 | 6 | 64780 | 17970 | 29491771 |
Listeria encephalitis | 22.08 | 10.71 | 7 | 64779 | 44 | 29509697 |
Mucosal inflammation | 22.01 | 10.71 | 22 | 64764 | 31573 | 29478168 |
Pulmonary vasculitis | 21.91 | 10.71 | 9 | 64777 | 128 | 29509613 |
Cytomegalovirus chorioretinitis | 21.82 | 10.71 | 31 | 64755 | 3207 | 29506534 |
Subcutaneous abscess | 21.79 | 10.71 | 32 | 64754 | 3412 | 29506329 |
Stiff person syndrome | 21.74 | 10.71 | 8 | 64778 | 83 | 29509658 |
Narcotic bowel syndrome | 21.66 | 10.71 | 9 | 64777 | 132 | 29509609 |
Herpes simplex hepatitis | 21.57 | 10.71 | 8 | 64778 | 85 | 29509656 |
Growth retardation | 21.51 | 10.71 | 22 | 64764 | 1614 | 29508127 |
Stevens-Johnson syndrome | 21.26 | 10.71 | 5 | 64781 | 16492 | 29493249 |
Metabolic acidosis | 21.18 | 10.71 | 31 | 64755 | 37631 | 29472110 |
Viral infection | 21.15 | 10.71 | 76 | 64710 | 14734 | 29495007 |
Cutaneous leishmaniasis | 21.12 | 10.71 | 10 | 64776 | 203 | 29509538 |
Myasthenia gravis | 20.99 | 10.71 | 30 | 64756 | 3121 | 29506620 |
Congenital oesophageal anomaly | 20.93 | 10.71 | 8 | 64778 | 93 | 29509648 |
Oesophageal atresia | 20.92 | 10.71 | 13 | 64773 | 460 | 29509281 |
Hyperkalaemia | 20.84 | 10.71 | 67 | 64719 | 61325 | 29448416 |
Pyoderma gangrenosum | 20.76 | 10.71 | 18 | 64768 | 1071 | 29508670 |
Subdural haematoma | 20.69 | 10.71 | 7 | 64779 | 18186 | 29491555 |
Coronary artery disease | 20.60 | 10.71 | 41 | 64745 | 44149 | 29465592 |
Osteoporosis | 20.55 | 10.71 | 61 | 64725 | 10708 | 29499033 |
Laryngeal mass | 20.41 | 10.71 | 6 | 64780 | 28 | 29509713 |
Congenital cystic lung | 20.39 | 10.71 | 10 | 64776 | 220 | 29509521 |
Lymphocytic infiltration | 20.33 | 10.71 | 14 | 64772 | 591 | 29509150 |
Heart rate decreased | 20.32 | 10.71 | 108 | 64678 | 24804 | 29484937 |
Combined immunodeficiency | 20.30 | 10.71 | 7 | 64779 | 59 | 29509682 |
Angioedema | 20.27 | 10.71 | 24 | 64762 | 31891 | 29477850 |
Immunosuppressant drug level increased | 20.27 | 10.71 | 37 | 64749 | 4728 | 29505013 |
Suicide attempt | 20.26 | 10.71 | 27 | 64759 | 34083 | 29475658 |
Rhabdomyolysis | 20.20 | 10.71 | 67 | 64719 | 60741 | 29449000 |
Haemolysis | 20.07 | 10.71 | 46 | 64740 | 6910 | 29502831 |
Ileal ulcer | 19.63 | 10.71 | 13 | 64773 | 514 | 29509227 |
Gastrointestinal stoma complication | 19.62 | 10.71 | 18 | 64768 | 1154 | 29508587 |
Hepatic enzyme increased | 19.56 | 10.71 | 134 | 64652 | 33665 | 29476076 |
Odynophagia | 19.53 | 10.71 | 36 | 64750 | 4634 | 29505107 |
Paracoccidioides infection | 19.43 | 10.71 | 7 | 64779 | 68 | 29509673 |
Central nervous system lesion | 19.31 | 10.71 | 40 | 64746 | 5608 | 29504133 |
Amnesia | 19.20 | 10.71 | 13 | 64773 | 22630 | 29487111 |
Iron deficiency | 19.12 | 10.71 | 28 | 64758 | 2977 | 29506764 |
Autoimmune haemolytic anaemia | 19.12 | 10.71 | 32 | 64754 | 3816 | 29505925 |
Cytomegalovirus test positive | 19.10 | 10.71 | 30 | 64756 | 3393 | 29506348 |
Gastrointestinal mucosa hyperaemia | 19.05 | 10.71 | 10 | 64776 | 255 | 29509486 |
Cytokine release syndrome | 18.97 | 10.71 | 3 | 64783 | 13116 | 29496625 |
Large intestinal ulcer | 18.96 | 10.71 | 21 | 64765 | 1688 | 29508053 |
Gastrointestinal stenosis | 18.90 | 10.71 | 7 | 64779 | 74 | 29509667 |
Mucocutaneous leishmaniasis | 18.82 | 10.71 | 7 | 64779 | 75 | 29509666 |
Hypersensitivity vasculitis | 18.81 | 10.71 | 29 | 64757 | 3228 | 29506513 |
Gallbladder polyp | 18.78 | 10.71 | 11 | 64775 | 349 | 29509392 |
Cardiac disorder | 18.76 | 10.71 | 33 | 64753 | 37230 | 29472511 |
Granuloma | 18.72 | 10.71 | 25 | 64761 | 2439 | 29507302 |
Autoimmune neutropenia | 18.70 | 10.71 | 10 | 64776 | 265 | 29509476 |
Anal cancer | 18.67 | 10.71 | 11 | 64775 | 353 | 29509388 |
Pneumonia cytomegaloviral | 18.55 | 10.71 | 26 | 64760 | 2656 | 29507085 |
Chorioretinopathy | 18.54 | 10.71 | 19 | 64767 | 1397 | 29508344 |
Episcleritis | 18.51 | 10.71 | 8 | 64778 | 130 | 29509611 |
Full blood count decreased | 18.45 | 10.71 | 6 | 64780 | 15986 | 29493755 |
Retinal scar | 18.40 | 10.71 | 10 | 64776 | 274 | 29509467 |
Herpes simplex test positive | 18.22 | 10.71 | 9 | 64777 | 201 | 29509540 |
Hodgkin's disease | 18.13 | 10.71 | 15 | 64771 | 837 | 29508904 |
Pseudopolyp | 18.10 | 10.71 | 9 | 64777 | 204 | 29509537 |
Pancreatitis acute | 18.07 | 10.71 | 103 | 64683 | 24282 | 29485459 |
Diabetes mellitus | 18.02 | 10.71 | 149 | 64637 | 39682 | 29470059 |
Pneumatosis intestinalis | 18.00 | 10.71 | 28 | 64758 | 3141 | 29506600 |
Polyomavirus-associated nephropathy | 17.90 | 10.71 | 29 | 64757 | 3367 | 29506374 |
Blood creatine phosphokinase increased | 17.86 | 10.71 | 39 | 64747 | 40605 | 29469136 |
Pulmonary granuloma | 17.74 | 10.71 | 18 | 64768 | 1308 | 29508433 |
Butterfly rash | 17.54 | 10.71 | 7 | 64779 | 92 | 29509649 |
Gastroenteritis clostridial | 17.52 | 10.71 | 9 | 64777 | 219 | 29509522 |
Arthritis | 17.45 | 10.71 | 104 | 64682 | 24915 | 29484826 |
Chest pain | 17.42 | 10.71 | 159 | 64627 | 111814 | 29397927 |
Haematuria | 17.29 | 10.71 | 45 | 64741 | 44094 | 29465647 |
Relapsing fever | 17.28 | 10.71 | 8 | 64778 | 154 | 29509587 |
Brain abscess | 17.28 | 10.71 | 25 | 64761 | 2630 | 29507111 |
Disturbance in attention | 17.25 | 10.71 | 13 | 64773 | 21411 | 29488330 |
Rectal cancer | 17.22 | 10.71 | 21 | 64765 | 1871 | 29507870 |
Erectile dysfunction | 17.16 | 10.71 | 9 | 64777 | 18000 | 29491741 |
Aspartate aminotransferase increased | 17.08 | 10.71 | 70 | 64716 | 59655 | 29450086 |
Drug specific antibody absent | 17.06 | 10.71 | 6 | 64780 | 54 | 29509687 |
Weight increased | 17.06 | 10.71 | 249 | 64537 | 76418 | 29433323 |
Drug ineffective for unapproved indication | 17.05 | 10.71 | 69 | 64717 | 14145 | 29495596 |
Platelet count decreased | 17.00 | 10.71 | 147 | 64639 | 104525 | 29405216 |
Cytomegalovirus duodenitis | 16.96 | 10.71 | 6 | 64780 | 55 | 29509686 |
Depression | 16.93 | 10.71 | 113 | 64673 | 85034 | 29424707 |
Intestinal ulcer | 16.92 | 10.71 | 14 | 64772 | 781 | 29508960 |
Lactic acidosis | 16.91 | 10.71 | 25 | 64761 | 30222 | 29479519 |
Laser therapy | 16.85 | 10.71 | 4 | 64782 | 6 | 29509735 |
Intestinal diaphragm disease | 16.78 | 10.71 | 9 | 64777 | 240 | 29509501 |
Serum sickness | 16.74 | 10.71 | 20 | 64766 | 1745 | 29507996 |
Cryptococcosis | 16.70 | 10.71 | 21 | 64765 | 1931 | 29507810 |
Hyperglycaemia | 16.69 | 10.71 | 31 | 64755 | 34256 | 29475485 |
Oesophagopleural fistula | 16.68 | 10.71 | 6 | 64780 | 58 | 29509683 |
Splenic embolism | 16.65 | 10.71 | 8 | 64778 | 168 | 29509573 |
Hemivertebra | 16.64 | 10.71 | 7 | 64779 | 106 | 29509635 |
Mental status changes | 16.63 | 10.71 | 32 | 64754 | 34895 | 29474846 |
Testicular cancer metastatic | 16.50 | 10.71 | 6 | 64780 | 60 | 29509681 |
Acne | 16.45 | 10.71 | 51 | 64735 | 9169 | 29500572 |
Cytomegalovirus syndrome | 16.41 | 10.71 | 7 | 64779 | 110 | 29509631 |
Gastrointestinal obstruction | 16.26 | 10.71 | 13 | 64773 | 691 | 29509050 |
Marrow hyperplasia | 16.17 | 10.71 | 15 | 64771 | 976 | 29508765 |
Injection site pain | 16.09 | 10.71 | 29 | 64757 | 32417 | 29477324 |
Dyspnoea exertional | 16.05 | 10.71 | 35 | 64751 | 36455 | 29473286 |
Neutropenia | 16.04 | 10.71 | 198 | 64588 | 131513 | 29378228 |
Haemorrhage intracranial | 15.84 | 10.71 | 6 | 64780 | 14536 | 29495205 |
Proctocolectomy | 15.75 | 10.71 | 6 | 64780 | 69 | 29509672 |
Gastric fistula | 15.67 | 10.71 | 6 | 64780 | 70 | 29509671 |
Cryptococcal cutaneous infection | 15.67 | 10.71 | 6 | 64780 | 70 | 29509671 |
Viral test positive | 15.53 | 10.71 | 8 | 64778 | 196 | 29509545 |
Arrhythmia | 15.52 | 10.71 | 28 | 64758 | 31285 | 29478456 |
Anorectal stenosis | 15.51 | 10.71 | 4 | 64782 | 10 | 29509731 |
Cardiac myxoma | 15.51 | 10.71 | 4 | 64782 | 10 | 29509731 |
Aplasia pure red cell | 15.50 | 10.71 | 36 | 64750 | 5455 | 29504286 |
Peripheral T-cell lymphoma unspecified stage IV | 15.43 | 10.71 | 5 | 64781 | 34 | 29509707 |
Urinary tract infection | 15.42 | 10.71 | 94 | 64692 | 72260 | 29437481 |
Spermatozoa progressive motility decreased | 15.40 | 10.71 | 7 | 64779 | 129 | 29509612 |
Aqueductal stenosis | 15.38 | 10.71 | 3 | 64783 | 0 | 29509741 |
Uveal melanoma | 15.38 | 10.71 | 3 | 64783 | 0 | 29509741 |
Dry mouth | 15.37 | 10.71 | 15 | 64771 | 21769 | 29487972 |
Disseminated cytomegaloviral infection | 15.34 | 10.71 | 8 | 64778 | 201 | 29509540 |
Proctitis | 15.34 | 10.71 | 21 | 64765 | 2098 | 29507643 |
Aphthous ulcer | 15.33 | 10.71 | 30 | 64756 | 4038 | 29505703 |
Tuberculosis gastrointestinal | 15.31 | 10.71 | 8 | 64778 | 202 | 29509539 |
Skin cancer | 15.25 | 10.71 | 47 | 64739 | 8421 | 29501320 |
Pneumoperitoneum | 15.21 | 10.71 | 18 | 64768 | 1555 | 29508186 |
Ejection fraction decreased | 15.20 | 10.71 | 8 | 64778 | 15970 | 29493771 |
Listeriosis | 15.18 | 10.71 | 14 | 64772 | 904 | 29508837 |
Sideroblastic anaemia | 15.03 | 10.71 | 8 | 64778 | 210 | 29509531 |
Anal stenosis | 14.97 | 10.71 | 7 | 64779 | 138 | 29509603 |
Skin lesion | 14.79 | 10.71 | 80 | 64706 | 18492 | 29491249 |
Sleep disorder | 14.79 | 10.71 | 19 | 64767 | 24367 | 29485374 |
Infectious mononucleosis | 14.68 | 10.71 | 11 | 64775 | 531 | 29509210 |
Intentional product misuse | 14.63 | 10.71 | 34 | 64752 | 34627 | 29475114 |
Coloboma | 14.61 | 10.71 | 7 | 64779 | 146 | 29509595 |
Urinary incontinence | 14.61 | 10.71 | 9 | 64777 | 16472 | 29493269 |
Extrapyramidal disorder | 14.53 | 10.71 | 3 | 64783 | 10828 | 29498913 |
Meconium peritonitis | 14.52 | 10.71 | 4 | 64782 | 14 | 29509727 |
Herpes simplex colitis | 14.52 | 10.71 | 4 | 64782 | 14 | 29509727 |
Respiratory tract infection fungal | 14.51 | 10.71 | 12 | 64774 | 669 | 29509072 |
Anaplastic large cell lymphoma T- and null-cell types | 14.50 | 10.71 | 6 | 64780 | 87 | 29509654 |
Memory impairment | 14.43 | 10.71 | 37 | 64749 | 36433 | 29473308 |
Epstein-Barr viraemia | 14.42 | 10.71 | 14 | 64772 | 964 | 29508777 |
Acute pulmonary histoplasmosis | 14.40 | 10.71 | 7 | 64779 | 151 | 29509590 |
Hepatitis B | 14.39 | 10.71 | 35 | 64751 | 5462 | 29504279 |
Metastases to lymph nodes | 14.39 | 10.71 | 29 | 64757 | 3988 | 29505753 |
Optic neuritis | 14.32 | 10.71 | 25 | 64761 | 3084 | 29506657 |
Ventricular tachycardia | 14.31 | 10.71 | 17 | 64769 | 22557 | 29487184 |
Lymph node tuberculosis | 14.28 | 10.71 | 10 | 64776 | 434 | 29509307 |
Pulmonary nocardiosis | 14.24 | 10.71 | 11 | 64775 | 556 | 29509185 |
Therapy non-responder | 14.18 | 10.71 | 116 | 64670 | 30795 | 29478946 |
Dementia | 14.13 | 10.71 | 4 | 64782 | 11654 | 29498087 |
Mycobacterium kansasii infection | 14.12 | 10.71 | 8 | 64778 | 238 | 29509503 |
Tender joint count increased | 14.12 | 10.71 | 5 | 64781 | 46 | 29509695 |
Neoplasm progression | 14.10 | 10.71 | 12 | 64774 | 18600 | 29491141 |
Haemophilus bacteraemia | 14.10 | 10.71 | 4 | 64782 | 16 | 29509725 |
Pulmonary paracoccidioidomycosis | 14.10 | 10.71 | 4 | 64782 | 16 | 29509725 |
Mycobacterium abscessus infection | 14.08 | 10.71 | 10 | 64776 | 444 | 29509297 |
Functional gastrointestinal disorder | 14.07 | 10.71 | 20 | 64766 | 2070 | 29507671 |
Rectal discharge | 14.07 | 10.71 | 7 | 64779 | 159 | 29509582 |
Jejunal stenosis | 14.02 | 10.71 | 5 | 64781 | 47 | 29509694 |
Small intestinal ulcer haemorrhage | 14.02 | 10.71 | 5 | 64781 | 47 | 29509694 |
Drug tolerance decreased | 14.01 | 10.71 | 16 | 64770 | 1330 | 29508411 |
Neonatal respiratory failure | 14.00 | 10.71 | 9 | 64777 | 338 | 29509403 |
Prostatic specific antigen increased | 14.00 | 10.71 | 5 | 64781 | 12559 | 29497182 |
Disseminated cryptococcosis | 13.98 | 10.71 | 15 | 64771 | 1163 | 29508578 |
Nausea | 13.95 | 10.71 | 506 | 64280 | 288749 | 29220992 |
Neoplasm skin | 13.87 | 10.71 | 11 | 64775 | 578 | 29509163 |
Migraine | 13.86 | 10.71 | 59 | 64727 | 12371 | 29497370 |
Vitamin B1 decreased | 13.82 | 10.71 | 8 | 64778 | 248 | 29509493 |
Intentional self-injury | 13.81 | 10.71 | 5 | 64781 | 12456 | 29497285 |
Thrombocytopenia | 13.78 | 10.71 | 210 | 64576 | 134613 | 29375128 |
Pruritus | 13.72 | 10.71 | 177 | 64609 | 116672 | 29393069 |
Skin papilloma | 13.68 | 10.71 | 18 | 64768 | 1731 | 29508010 |
Hypervolaemia | 13.68 | 10.71 | 11 | 64775 | 17534 | 29492207 |
Unevaluable event | 13.65 | 10.71 | 28 | 64758 | 29823 | 29479918 |
Uveitis | 13.62 | 10.71 | 36 | 64750 | 5911 | 29503830 |
Campylobacter gastroenteritis | 13.56 | 10.71 | 12 | 64774 | 734 | 29509007 |
Necrotising herpetic retinopathy | 13.55 | 10.71 | 4 | 64782 | 19 | 29509722 |
Enterovesical fistula | 13.45 | 10.71 | 11 | 64775 | 604 | 29509137 |
Peritoneal candidiasis | 13.38 | 10.71 | 4 | 64782 | 20 | 29509721 |
Hepatobiliary cancer | 13.31 | 10.71 | 3 | 64783 | 3 | 29509738 |
Precursor T-lymphoblastic lymphoma/leukaemia stage I | 13.31 | 10.71 | 3 | 64783 | 3 | 29509738 |
Hepatic angiosarcoma | 13.31 | 10.71 | 3 | 64783 | 3 | 29509738 |
Leiomyoma | 13.31 | 10.71 | 3 | 64783 | 3 | 29509738 |
Leiomyosarcoma metastatic | 13.31 | 10.71 | 3 | 64783 | 3 | 29509738 |
Blood bilirubin decreased | 13.29 | 10.71 | 8 | 64778 | 267 | 29509474 |
Aspiration | 13.29 | 10.71 | 3 | 64783 | 10177 | 29499564 |
Olfactory nerve disorder | 13.22 | 10.71 | 4 | 64782 | 21 | 29509720 |
Vomiting | 13.20 | 10.71 | 359 | 64427 | 211901 | 29297840 |
Overgrowth bacterial | 13.18 | 10.71 | 6 | 64780 | 111 | 29509630 |
Hyperhidrosis | 13.16 | 10.71 | 85 | 64701 | 64455 | 29445286 |
Skin hyperpigmentation | 13.16 | 10.71 | 23 | 64763 | 2841 | 29506900 |
Haematemesis | 13.14 | 10.71 | 21 | 64765 | 24605 | 29485136 |
Pain | 13.12 | 10.71 | 281 | 64505 | 171151 | 29338590 |
Hepatitis cholestatic | 13.11 | 10.71 | 39 | 64747 | 6854 | 29502887 |
Pneumocystis jirovecii infection | 13.07 | 10.71 | 16 | 64770 | 1432 | 29508309 |
Small intestine carcinoma | 13.00 | 10.71 | 10 | 64776 | 502 | 29509239 |
Oropharyngeal pain | 12.95 | 10.71 | 109 | 64677 | 29176 | 29480565 |
Brachycephaly | 12.94 | 10.71 | 5 | 64781 | 60 | 29509681 |
Diffuse large B-cell lymphoma stage III | 12.94 | 10.71 | 5 | 64781 | 60 | 29509681 |
Gastrointestinal scarring | 12.94 | 10.71 | 6 | 64780 | 116 | 29509625 |
Pulmonary oedema | 12.91 | 10.71 | 49 | 64737 | 42686 | 29467055 |
Oropharyngeal squamous cell carcinoma | 12.87 | 10.71 | 7 | 64779 | 192 | 29509549 |
Cholangitis chronic | 12.84 | 10.71 | 3 | 64783 | 4 | 29509737 |
Arthropathy | 12.79 | 10.71 | 86 | 64700 | 21468 | 29488273 |
Epstein-Barr virus antibody positive | 12.78 | 10.71 | 8 | 64778 | 287 | 29509454 |
Posterior reversible encephalopathy syndrome | 12.76 | 10.71 | 46 | 64740 | 8930 | 29500811 |
Gastrointestinal oedema | 12.76 | 10.71 | 15 | 64771 | 1286 | 29508455 |
Poor venous access | 12.76 | 10.71 | 24 | 64762 | 3137 | 29506604 |
Small intestine adenocarcinoma | 12.75 | 10.71 | 6 | 64780 | 120 | 29509621 |
Pseudolymphoma | 12.75 | 10.71 | 10 | 64776 | 517 | 29509224 |
Human ehrlichiosis | 12.74 | 10.71 | 7 | 64779 | 196 | 29509545 |
Myelitis transverse | 12.73 | 10.71 | 13 | 64773 | 952 | 29508789 |
Skin laceration | 12.72 | 10.71 | 53 | 64733 | 11009 | 29498732 |
Brain stem syndrome | 12.70 | 10.71 | 9 | 64777 | 398 | 29509343 |
Rash maculo-papular | 12.69 | 10.71 | 21 | 64765 | 24268 | 29485473 |
Fluid retention | 12.66 | 10.71 | 20 | 64766 | 23540 | 29486201 |
Henoch-Schonlein purpura | 12.62 | 10.71 | 15 | 64771 | 1301 | 29508440 |
Appendicectomy | 12.61 | 10.71 | 12 | 64774 | 806 | 29508935 |
Altered state of consciousness | 12.58 | 10.71 | 15 | 64771 | 19874 | 29489867 |
Cognitive disorder | 12.58 | 10.71 | 20 | 64766 | 23479 | 29486262 |
Diaphragmatic injury | 12.57 | 10.71 | 6 | 64780 | 124 | 29509617 |
Antiphospholipid syndrome | 12.56 | 10.71 | 9 | 64777 | 405 | 29509336 |
Cytomegalovirus oesophagitis | 12.52 | 10.71 | 9 | 64777 | 407 | 29509334 |
Oedema | 12.50 | 10.71 | 46 | 64740 | 40437 | 29469304 |
Drug interaction | 12.49 | 10.71 | 333 | 64453 | 197052 | 29312689 |
Accidental exposure to product | 12.47 | 10.71 | 4 | 64782 | 10749 | 29498992 |
Diarrhoea | 12.45 | 10.71 | 599 | 64187 | 332099 | 29177642 |
Microscopic polyangiitis | 12.44 | 10.71 | 6 | 64780 | 127 | 29509614 |
Placental disorder | 12.44 | 10.71 | 5 | 64781 | 67 | 29509674 |
Lymphocyte count | 12.44 | 10.71 | 5 | 64781 | 67 | 29509674 |
Polydipsia | 12.39 | 10.71 | 25 | 64761 | 3440 | 29506301 |
Colonic abscess | 12.37 | 10.71 | 9 | 64777 | 415 | 29509326 |
Caesarean section | 12.36 | 10.71 | 18 | 64768 | 1905 | 29507836 |
Leiomyosarcoma | 12.27 | 10.71 | 6 | 64780 | 131 | 29509610 |
Toxic epidermal necrolysis | 12.24 | 10.71 | 13 | 64773 | 18140 | 29491601 |
Short-bowel syndrome | 12.18 | 10.71 | 7 | 64779 | 214 | 29509527 |
Vision blurred | 12.18 | 10.71 | 46 | 64740 | 40130 | 29469611 |
Musculoskeletal discomfort | 12.18 | 10.71 | 36 | 64750 | 6305 | 29503436 |
Lip swelling | 12.12 | 10.71 | 6 | 64780 | 12404 | 29497337 |
Antibody test abnormal | 12.11 | 10.71 | 6 | 64780 | 135 | 29509606 |
Anaplastic large cell lymphoma T- and null-cell types stage III | 12.10 | 10.71 | 3 | 64783 | 6 | 29509735 |
Protein deficiency | 12.10 | 10.71 | 3 | 64783 | 6 | 29509735 |
Actinic cheilitis | 12.10 | 10.71 | 3 | 64783 | 6 | 29509735 |
Alternaria infection | 12.02 | 10.71 | 8 | 64778 | 319 | 29509422 |
Gastrointestinal cancer metastatic | 11.99 | 10.71 | 5 | 64781 | 74 | 29509667 |
Pneumonia legionella | 11.87 | 10.71 | 16 | 64770 | 1575 | 29508166 |
Blood sodium decreased | 11.84 | 10.71 | 9 | 64777 | 14758 | 29494983 |
Muscle rigidity | 11.84 | 10.71 | 3 | 64783 | 9408 | 29500333 |
Eosinophilic myocarditis | 11.80 | 10.71 | 9 | 64777 | 446 | 29509295 |
Alanine aminotransferase increased | 11.79 | 10.71 | 99 | 64687 | 70845 | 29438896 |
Central nervous system lymphoma | 11.76 | 10.71 | 11 | 64775 | 723 | 29509018 |
Death neonatal | 11.76 | 10.71 | 8 | 64778 | 331 | 29509410 |
Focal segmental glomerulosclerosis | 11.74 | 10.71 | 17 | 64769 | 1790 | 29507951 |
Haemodialysis | 11.69 | 10.71 | 48 | 64738 | 9906 | 29499835 |
Neurological symptom | 11.68 | 10.71 | 24 | 64762 | 3346 | 29506395 |
Chronic graft versus host disease in liver | 11.63 | 10.71 | 8 | 64778 | 337 | 29509404 |
Scar | 11.61 | 10.71 | 32 | 64754 | 5387 | 29504354 |
Adenocarcinoma | 11.61 | 10.71 | 16 | 64770 | 1609 | 29508132 |
Vasculitis necrotising | 11.54 | 10.71 | 10 | 64776 | 595 | 29509146 |
Hair follicle tumour benign | 11.50 | 10.71 | 3 | 64783 | 8 | 29509733 |
Lymphadenopathy | 11.48 | 10.71 | 94 | 64692 | 24955 | 29484786 |
Adverse drug reaction | 11.44 | 10.71 | 22 | 64764 | 23998 | 29485743 |
Testis cancer | 11.43 | 10.71 | 12 | 64774 | 908 | 29508833 |
Diabetic ketoacidosis | 11.42 | 10.71 | 11 | 64775 | 16062 | 29493679 |
Gastrointestinal stoma output decreased | 11.37 | 10.71 | 4 | 64782 | 36 | 29509705 |
Food intolerance | 11.37 | 10.71 | 13 | 64773 | 1082 | 29508659 |
Peritoneal tuberculosis | 11.30 | 10.71 | 8 | 64778 | 353 | 29509388 |
American trypanosomiasis | 11.28 | 10.71 | 7 | 64779 | 247 | 29509494 |
Withdrawal syndrome | 11.22 | 10.71 | 5 | 64781 | 10987 | 29498754 |
Underdose | 11.21 | 10.71 | 6 | 64780 | 11863 | 29497878 |
Rhegmatogenous retinal detachment | 11.18 | 10.71 | 4 | 64782 | 38 | 29509703 |
Opportunistic infection | 11.15 | 10.71 | 15 | 64771 | 1474 | 29508267 |
Product administration error | 11.12 | 10.71 | 9 | 64777 | 14301 | 29495440 |
Enterostomy | 11.10 | 10.71 | 5 | 64781 | 90 | 29509651 |
Congenital arterial malformation | 11.10 | 10.71 | 5 | 64781 | 90 | 29509651 |
Liver disorder | 11.08 | 10.71 | 101 | 64685 | 27648 | 29482093 |
Complications of transplanted heart | 11.08 | 10.71 | 7 | 64779 | 255 | 29509486 |
Sacroiliitis | 11.07 | 10.71 | 13 | 64773 | 1114 | 29508627 |
Diaphragmatic hernia | 11.06 | 10.71 | 7 | 64779 | 256 | 29509485 |
Acute respiratory failure | 11.06 | 10.71 | 26 | 64760 | 26376 | 29483365 |
Anger | 11.05 | 10.71 | 5 | 64781 | 10885 | 29498856 |
Dysarthria | 11.00 | 10.71 | 33 | 64753 | 30878 | 29478863 |
Angina unstable | 11.00 | 10.71 | 5 | 64781 | 10860 | 29498881 |
Perineal fistula | 11 | 10.71 | 3 | 64783 | 10 | 29509731 |
Foetal cardiac disorder | 11 | 10.71 | 3 | 64783 | 10 | 29509731 |
Mediastinum neoplasm | 11 | 10.71 | 3 | 64783 | 10 | 29509731 |
Hodgkin's disease nodular sclerosis | 11 | 10.71 | 3 | 64783 | 10 | 29509731 |
Ophthalmic herpes simplex | 10.99 | 10.71 | 7 | 64779 | 259 | 29509482 |
Drug specific antibody | 10.99 | 10.71 | 7 | 64779 | 259 | 29509482 |
Xanthoma | 10.96 | 10.71 | 5 | 64781 | 93 | 29509648 |
Ageusia | 10.95 | 10.71 | 3 | 64783 | 8935 | 29500806 |
Stenotrophomonas infection | 10.93 | 10.71 | 16 | 64770 | 1701 | 29508040 |
Back pain | 10.90 | 10.71 | 158 | 64628 | 102126 | 29407615 |
Anorectal disorder | 10.87 | 10.71 | 12 | 64774 | 961 | 29508780 |
Rectal stenosis | 10.86 | 10.71 | 6 | 64780 | 170 | 29509571 |
Restlessness | 10.80 | 10.71 | 20 | 64766 | 22125 | 29487616 |
Immunosuppressant drug level decreased | 10.78 | 10.71 | 13 | 64773 | 1145 | 29508596 |
Bile duct stenosis | 10.76 | 10.71 | 13 | 64773 | 1147 | 29508594 |
Hepatitis chronic active | 10.74 | 10.71 | 4 | 64782 | 43 | 29509698 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Off label use | 931.34 | 9.77 | 3373 | 144871 | 629433 | 63721055 |
Drug ineffective | 701.49 | 9.77 | 3780 | 144464 | 836467 | 63514021 |
Colitis ulcerative | 541.05 | 9.77 | 438 | 147806 | 22590 | 64327898 |
Completed suicide | 471.23 | 9.77 | 9 | 148235 | 224405 | 64126083 |
Post transplant lymphoproliferative disorder | 395.13 | 9.77 | 256 | 147988 | 9288 | 64341200 |
Cytomegalovirus infection | 371.70 | 9.77 | 443 | 147801 | 36756 | 64313732 |
Death | 362.28 | 9.77 | 346 | 147898 | 482359 | 63868129 |
Exposure during pregnancy | 358.91 | 9.77 | 642 | 147602 | 77033 | 64273455 |
Treatment failure | 356.12 | 9.77 | 812 | 147432 | 116004 | 64234484 |
Intentional product use issue | 312.06 | 9.77 | 682 | 147562 | 94682 | 64255806 |
Intestinal stenosis | 309.09 | 9.77 | 150 | 148094 | 3064 | 64347424 |
Product use in unapproved indication | 306.88 | 9.77 | 998 | 147246 | 175620 | 64174868 |
Fall | 305.39 | 9.77 | 305 | 147939 | 416521 | 63933967 |
Condition aggravated | 305.02 | 9.77 | 1671 | 146573 | 370755 | 63979733 |
Epstein-Barr virus infection | 296.41 | 9.77 | 239 | 148005 | 12249 | 64338239 |
Product use issue | 266.83 | 9.77 | 861 | 147383 | 150854 | 64199634 |
Hepatosplenic T-cell lymphoma | 263.51 | 9.77 | 91 | 148153 | 731 | 64349757 |
Disease recurrence | 244.64 | 9.77 | 331 | 147913 | 31179 | 64319309 |
Drug abuse | 241.41 | 9.77 | 16 | 148228 | 132358 | 64218130 |
Diffuse large B-cell lymphoma | 238.95 | 9.77 | 195 | 148049 | 10166 | 64340322 |
Toxicity to various agents | 237.53 | 9.77 | 292 | 147952 | 363221 | 63987267 |
Cushingoid | 232.04 | 9.77 | 169 | 148075 | 7434 | 64343054 |
Drug level below therapeutic | 231.89 | 9.77 | 167 | 148077 | 7217 | 64343271 |
Fistula | 221.52 | 9.77 | 182 | 148062 | 9579 | 64340909 |
Frequent bowel movements | 216.63 | 9.77 | 238 | 148006 | 18067 | 64332421 |
Drug intolerance | 216.60 | 9.77 | 931 | 147313 | 187061 | 64163427 |
Anal abscess | 206.99 | 9.77 | 157 | 148087 | 7351 | 64343137 |
Haemophagocytic lymphohistiocytosis | 206.74 | 9.77 | 228 | 148016 | 17381 | 64333107 |
Premature delivery | 205.07 | 9.77 | 233 | 148011 | 18356 | 64332132 |
Anal fistula | 203.05 | 9.77 | 135 | 148109 | 5118 | 64345370 |
Hypotension | 192.12 | 9.77 | 365 | 147879 | 380609 | 63969879 |
Lymphoproliferative disorder | 189.69 | 9.77 | 128 | 148116 | 4975 | 64345513 |
Maternal exposure during pregnancy | 186.77 | 9.77 | 564 | 147680 | 95320 | 64255168 |
Nodular regenerative hyperplasia | 184.47 | 9.77 | 71 | 148173 | 799 | 64349689 |
Ileal stenosis | 184.45 | 9.77 | 92 | 148152 | 1998 | 64348490 |
Faecal calprotectin increased | 181.79 | 9.77 | 110 | 148134 | 3530 | 64346958 |
Drug eruption | 180.20 | 9.77 | 309 | 147935 | 35827 | 64314661 |
Inappropriate schedule of product administration | 177.08 | 9.77 | 540 | 147704 | 91746 | 64258742 |
Transplant rejection | 175.04 | 9.77 | 208 | 148036 | 17193 | 64333295 |
Disseminated tuberculosis | 171.42 | 9.77 | 106 | 148138 | 3539 | 64346949 |
Febrile neutropenia | 163.31 | 9.77 | 116 | 148128 | 187541 | 64162947 |
Kidney transplant rejection | 162.74 | 9.77 | 151 | 148093 | 9360 | 64341128 |
Malignant neoplasm progression | 162.74 | 9.77 | 31 | 148213 | 112840 | 64237648 |
SLE arthritis | 162.19 | 9.77 | 57 | 148187 | 485 | 64350003 |
Epstein-Barr virus associated lymphoproliferative disorder | 160.28 | 9.77 | 96 | 148148 | 3023 | 64347465 |
Confusional state | 159.90 | 9.77 | 220 | 148024 | 260924 | 64089564 |
Squamous cell carcinoma | 158.38 | 9.77 | 177 | 148067 | 13692 | 64336796 |
Hyponatraemia | 154.14 | 9.77 | 74 | 148170 | 148265 | 64202223 |
Lupus-like syndrome | 151.25 | 9.77 | 140 | 148104 | 8651 | 64341837 |
Somnolence | 151.16 | 9.77 | 147 | 148097 | 203498 | 64146990 |
Blood pressure fluctuation | 148.50 | 9.77 | 352 | 147892 | 51519 | 64298969 |
Atrial fibrillation | 145.94 | 9.77 | 108 | 148136 | 170981 | 64179507 |
Progressive multifocal leukoencephalopathy | 145.28 | 9.77 | 194 | 148050 | 18038 | 64332450 |
Therapeutic response decreased | 143.86 | 9.77 | 349 | 147895 | 51839 | 64298649 |
Pancytopenia | 142.71 | 9.77 | 680 | 147564 | 142629 | 64207859 |
Bone erosion | 141.09 | 9.77 | 153 | 148091 | 11442 | 64339046 |
Pneumocystis jirovecii pneumonia | 140.02 | 9.77 | 238 | 148006 | 27396 | 64323092 |
Basal cell carcinoma | 139.91 | 9.77 | 253 | 147991 | 30585 | 64319903 |
Cytomegalovirus colitis | 135.29 | 9.77 | 94 | 148150 | 3834 | 64346654 |
Overdose | 134.45 | 9.77 | 102 | 148142 | 159464 | 64191024 |
Therapeutic product effect incomplete | 132.80 | 9.77 | 530 | 147714 | 102952 | 64247536 |
Intestinal obstruction | 131.89 | 9.77 | 271 | 147973 | 36015 | 64314473 |
Intestinal resection | 131.19 | 9.77 | 84 | 148160 | 2984 | 64347504 |
Large intestinal stenosis | 130.42 | 9.77 | 77 | 148167 | 2360 | 64348128 |
Therapeutic product effect decreased | 130.21 | 9.77 | 568 | 147676 | 114783 | 64235705 |
Vasculitis | 129.80 | 9.77 | 183 | 148061 | 17912 | 64332576 |
Cholestasis of pregnancy | 129.32 | 9.77 | 56 | 148188 | 869 | 64349619 |
Cardiac failure congestive | 128.41 | 9.77 | 70 | 148174 | 130510 | 64219978 |
Dizziness | 123.99 | 9.77 | 538 | 147706 | 429625 | 63920863 |
Demyelination | 121.79 | 9.77 | 111 | 148133 | 6723 | 64343765 |
B-cell lymphoma | 120.17 | 9.77 | 100 | 148144 | 5357 | 64345131 |
Cardio-respiratory arrest | 118.72 | 9.77 | 39 | 148205 | 98354 | 64252134 |
Haematochezia | 117.72 | 9.77 | 378 | 147866 | 65995 | 64284493 |
Cytomegalovirus viraemia | 116.52 | 9.77 | 134 | 148110 | 10694 | 64339794 |
Lung transplant rejection | 115.68 | 9.77 | 58 | 148186 | 1274 | 64349214 |
Intentional overdose | 115.13 | 9.77 | 32 | 148212 | 89912 | 64260576 |
Abscess | 115.11 | 9.77 | 179 | 148065 | 19125 | 64331363 |
Syncope | 113.26 | 9.77 | 117 | 148127 | 157518 | 64192970 |
Drug level decreased | 113.22 | 9.77 | 136 | 148108 | 11367 | 64339121 |
Pulmonary tuberculosis | 112.49 | 9.77 | 109 | 148135 | 7135 | 64343353 |
Elbow deformity | 112.07 | 9.77 | 56 | 148188 | 1221 | 64349267 |
Acute kidney injury | 110.21 | 9.77 | 595 | 147649 | 448645 | 63901843 |
Bradycardia | 109.66 | 9.77 | 68 | 148176 | 118151 | 64232337 |
Abdominal pain | 108.47 | 9.77 | 1146 | 147098 | 311229 | 64039259 |
Electrocardiogram QT prolonged | 104.08 | 9.77 | 27 | 148217 | 79421 | 64271067 |
Hypokalaemia | 103.87 | 9.77 | 77 | 148167 | 121826 | 64228662 |
Dyspnoea | 102.37 | 9.77 | 1108 | 147136 | 717566 | 63632922 |
Leukopenia | 101.91 | 9.77 | 482 | 147762 | 100760 | 64249728 |
Proteinuria | 101.87 | 9.77 | 208 | 148036 | 27515 | 64322973 |
Cardiac arrest | 101.22 | 9.77 | 123 | 148121 | 153941 | 64196547 |
Blood iron abnormal | 99.04 | 9.77 | 50 | 148194 | 1115 | 64349373 |
Premature labour | 98.81 | 9.77 | 104 | 148140 | 7516 | 64342972 |
Drug specific antibody present | 98.34 | 9.77 | 87 | 148157 | 5067 | 64345421 |
Loss of consciousness | 97.95 | 9.77 | 118 | 148126 | 148247 | 64202241 |
Colectomy | 97.74 | 9.77 | 66 | 148178 | 2568 | 64347920 |
Clostridium difficile infection | 97.69 | 9.77 | 240 | 148004 | 35923 | 64314565 |
Histoplasmosis disseminated | 96.24 | 9.77 | 59 | 148185 | 1939 | 64348549 |
Rheumatoid arthritis | 96.15 | 9.77 | 677 | 147567 | 163617 | 64186871 |
Tuberculosis | 95.21 | 9.77 | 133 | 148111 | 12905 | 64337583 |
Red blood cell sedimentation rate increased | 94.90 | 9.77 | 217 | 148027 | 31018 | 64319470 |
Clear cell renal cell carcinoma | 94.01 | 9.77 | 60 | 148184 | 2119 | 64348369 |
Hypoglycaemia | 93.11 | 9.77 | 45 | 148199 | 89847 | 64260641 |
Lupus nephritis | 92.97 | 9.77 | 62 | 148182 | 2362 | 64348126 |
Diarrhoea haemorrhagic | 91.81 | 9.77 | 121 | 148123 | 11106 | 64339382 |
Fatigue | 91.76 | 9.77 | 1193 | 147051 | 747537 | 63602951 |
Erythema nodosum | 91.57 | 9.77 | 75 | 148169 | 3929 | 64346559 |
Epstein-Barr virus test positive | 91.24 | 9.77 | 45 | 148199 | 953 | 64349535 |
Product dose omission issue | 90.79 | 9.77 | 195 | 148049 | 194552 | 64155936 |
Decreased appetite | 88.98 | 9.77 | 339 | 147905 | 280950 | 64069538 |
Intestinal fistula | 87.98 | 9.77 | 47 | 148197 | 1182 | 64349306 |
JC virus infection | 87.75 | 9.77 | 68 | 148176 | 3287 | 64347201 |
Kaposi's sarcoma | 87.55 | 9.77 | 40 | 148204 | 709 | 64349779 |
Myocardial infarction | 86.84 | 9.77 | 155 | 148089 | 165666 | 64184822 |
Scleritis | 86.15 | 9.77 | 64 | 148180 | 2902 | 64347586 |
Acute febrile neutrophilic dermatosis | 86.04 | 9.77 | 67 | 148177 | 3262 | 64347226 |
Antinuclear antibody positive | 85.89 | 9.77 | 88 | 148156 | 6162 | 64344326 |
Insomnia | 85.81 | 9.77 | 206 | 148038 | 197630 | 64152858 |
Neutrophil count decreased | 85.68 | 9.77 | 35 | 148209 | 77161 | 64273327 |
Arthritis | 85.04 | 9.77 | 400 | 147844 | 83414 | 64267074 |
Squamous cell carcinoma of skin | 85.02 | 9.77 | 120 | 148124 | 11756 | 64338732 |
Coma | 84.62 | 9.77 | 48 | 148196 | 87567 | 64262921 |
Hepatic function abnormal | 84.57 | 9.77 | 332 | 147912 | 63981 | 64286507 |
Histoplasmosis | 83.10 | 9.77 | 54 | 148190 | 1968 | 64348520 |
C-reactive protein increased | 82.85 | 9.77 | 434 | 147810 | 94475 | 64256013 |
Normal newborn | 82.52 | 9.77 | 82 | 148162 | 5535 | 64344953 |
Asthenia | 82.24 | 9.77 | 611 | 147633 | 427433 | 63923055 |
Sedation | 81.95 | 9.77 | 3 | 148241 | 41459 | 64309029 |
Anal fissure | 81.82 | 9.77 | 77 | 148167 | 4859 | 64345629 |
Cerebrovascular accident | 81.05 | 9.77 | 119 | 148125 | 137464 | 64213024 |
Immunosuppression | 80.53 | 9.77 | 111 | 148133 | 10635 | 64339853 |
Abortion spontaneous | 80.09 | 9.77 | 178 | 148066 | 24965 | 64325523 |
Mycobacterial infection | 79.11 | 9.77 | 61 | 148183 | 2927 | 64347561 |
Pre-eclampsia | 78.94 | 9.77 | 84 | 148160 | 6147 | 64344341 |
Chronic allograft nephropathy | 78.64 | 9.77 | 47 | 148197 | 1474 | 64349014 |
Arthralgia | 77.58 | 9.77 | 1437 | 146807 | 440823 | 63909665 |
Dehydration | 77.42 | 9.77 | 248 | 147996 | 216515 | 64133973 |
Nocardiosis | 76.42 | 9.77 | 73 | 148171 | 4694 | 64345794 |
Granulomatosis with polyangiitis | 76.00 | 9.77 | 52 | 148192 | 2068 | 64348420 |
Gastrointestinal inflammation | 75.82 | 9.77 | 82 | 148162 | 6113 | 64344375 |
Renal cell carcinoma | 75.06 | 9.77 | 81 | 148163 | 6023 | 64344465 |
Gastrointestinal lymphoma | 74.41 | 9.77 | 23 | 148221 | 124 | 64350364 |
Respiratory arrest | 73.34 | 9.77 | 16 | 148228 | 52969 | 64297519 |
T-cell lymphoma | 72.55 | 9.77 | 41 | 148203 | 1155 | 64349333 |
Epidermodysplasia verruciformis | 72.47 | 9.77 | 24 | 148220 | 167 | 64350321 |
Osteoporosis | 72.20 | 9.77 | 237 | 148007 | 41843 | 64308645 |
Impaired gastric emptying | 72.17 | 9.77 | 95 | 148149 | 8709 | 64341779 |
Contusion | 71.70 | 9.77 | 94 | 148150 | 113871 | 64236617 |
Therapeutic response shortened | 71.67 | 9.77 | 102 | 148142 | 10068 | 64340420 |
Weight decreased | 70.97 | 9.77 | 984 | 147260 | 284755 | 64065733 |
Inflammation | 70.95 | 9.77 | 318 | 147926 | 64982 | 64285506 |
Constipation | 70.18 | 9.77 | 280 | 147964 | 229057 | 64121431 |
Coombs positive haemolytic anaemia | 69.75 | 9.77 | 36 | 148208 | 842 | 64349646 |
Hair follicle tumour benign | 69.66 | 9.77 | 29 | 148215 | 406 | 64350082 |
Blood glucose increased | 69.06 | 9.77 | 74 | 148170 | 97999 | 64252489 |
Depressed level of consciousness | 68.63 | 9.77 | 52 | 148192 | 81384 | 64269104 |
Human herpesvirus 8 infection | 68.40 | 9.77 | 38 | 148206 | 1035 | 64349453 |
Colitis | 67.75 | 9.77 | 291 | 147953 | 58383 | 64292105 |
Synovial fluid analysis | 67.19 | 9.77 | 43 | 148201 | 1526 | 64348962 |
Hyperkalaemia | 67.19 | 9.77 | 80 | 148164 | 101049 | 64249439 |
Heart transplant rejection | 67.14 | 9.77 | 40 | 148204 | 1247 | 64349241 |
Gestational hypertension | 66.90 | 9.77 | 44 | 148200 | 1637 | 64348851 |
Bone marrow failure | 65.86 | 9.77 | 251 | 147993 | 47701 | 64302787 |
Lymphopenia | 65.85 | 9.77 | 167 | 148077 | 25490 | 64324998 |
Diabetes mellitus | 65.79 | 9.77 | 315 | 147929 | 66159 | 64284329 |
Pneumonia aspiration | 65.57 | 9.77 | 27 | 148217 | 59244 | 64291244 |
Tenosynovitis stenosans | 65.39 | 9.77 | 46 | 148198 | 1914 | 64348574 |
Orthostatic hypotension | 64.92 | 9.77 | 14 | 148230 | 46724 | 64303764 |
Epstein-Barr virus associated lymphoma | 64.89 | 9.77 | 35 | 148209 | 898 | 64349590 |
Chronic obstructive pulmonary disease | 64.32 | 9.77 | 42 | 148202 | 71006 | 64279482 |
Cholangitis sclerosing | 63.94 | 9.77 | 45 | 148199 | 1874 | 64348614 |
Platelet count decreased | 63.33 | 9.77 | 187 | 148057 | 167524 | 64182964 |
Extrapulmonary tuberculosis | 63.31 | 9.77 | 26 | 148218 | 351 | 64350137 |
Agitation | 62.98 | 9.77 | 66 | 148178 | 88301 | 64262187 |
Inflammatory bowel disease | 62.55 | 9.77 | 64 | 148180 | 4474 | 64346014 |
Hypogammaglobulinaemia | 62.10 | 9.77 | 96 | 148148 | 10203 | 64340285 |
Hallucination | 61.95 | 9.77 | 46 | 148198 | 72742 | 64277746 |
Aspergillus infection | 61.49 | 9.77 | 124 | 148120 | 16255 | 64334233 |
Plasmablastic lymphoma | 61.26 | 9.77 | 26 | 148218 | 383 | 64350105 |
Wrong technique in product usage process | 60.75 | 9.77 | 37 | 148207 | 64937 | 64285551 |
Small intestinal stenosis | 60.58 | 9.77 | 30 | 148214 | 641 | 64349847 |
Serotonin syndrome | 60.56 | 9.77 | 9 | 148235 | 39273 | 64311215 |
Papilloma viral infection | 59.93 | 9.77 | 39 | 148205 | 1425 | 64349063 |
Infusion related reaction | 59.62 | 9.77 | 609 | 147635 | 163858 | 64186630 |
Varicella zoster virus infection | 59.42 | 9.77 | 58 | 148186 | 3830 | 64346658 |
Immunosuppressant drug level decreased | 59.17 | 9.77 | 42 | 148202 | 1773 | 64348715 |
Pain | 59.10 | 9.77 | 906 | 147338 | 552605 | 63797883 |
Seizure | 58.83 | 9.77 | 192 | 148052 | 166700 | 64183788 |
Balance disorder | 58.34 | 9.77 | 64 | 148180 | 83862 | 64266626 |
Listeriosis | 58.32 | 9.77 | 43 | 148201 | 1927 | 64348561 |
Crohn's disease | 57.96 | 9.77 | 43 | 148201 | 1946 | 64348542 |
Rheumatoid nodule | 57.64 | 9.77 | 104 | 148140 | 12547 | 64337941 |
Acute myocardial infarction | 56.88 | 9.77 | 46 | 148198 | 69672 | 64280816 |
Drug tolerance decreased | 56.57 | 9.77 | 75 | 148169 | 6923 | 64343565 |
Tremor | 56.17 | 9.77 | 165 | 148079 | 148065 | 64202423 |
Anxiety | 56.10 | 9.77 | 257 | 147987 | 202392 | 64148096 |
Lactic acidosis | 56.00 | 9.77 | 36 | 148208 | 61374 | 64289114 |
Oedema peripheral | 55.72 | 9.77 | 271 | 147973 | 210046 | 64140442 |
Neuropathy peripheral | 55.31 | 9.77 | 117 | 148127 | 117408 | 64233080 |
Aphthous ulcer | 54.90 | 9.77 | 103 | 148141 | 12803 | 64337685 |
Central nervous system lymphoma | 54.52 | 9.77 | 41 | 148203 | 1894 | 64348594 |
Ankylosing spondylitis | 54.26 | 9.77 | 80 | 148164 | 8154 | 64342334 |
Episcleritis | 54.17 | 9.77 | 30 | 148214 | 812 | 64349676 |
Gastrointestinal haemorrhage | 54.06 | 9.77 | 142 | 148102 | 132170 | 64218318 |
Lymphoma | 52.88 | 9.77 | 106 | 148138 | 13835 | 64336653 |
Metabolic acidosis | 52.85 | 9.77 | 51 | 148193 | 70907 | 64279581 |
Defaecation urgency | 52.71 | 9.77 | 55 | 148189 | 3934 | 64346554 |
Unresponsive to stimuli | 52.52 | 9.77 | 25 | 148219 | 50368 | 64300120 |
Hypersensitivity | 52.21 | 9.77 | 685 | 147559 | 195767 | 64154721 |
International normalised ratio increased | 52.19 | 9.77 | 63 | 148181 | 79104 | 64271384 |
Depression | 51.60 | 9.77 | 231 | 148013 | 183060 | 64167428 |
Hepatic cirrhosis | 51.44 | 9.77 | 155 | 148089 | 26143 | 64324345 |
Delirium | 51.22 | 9.77 | 50 | 148194 | 69144 | 64281344 |
Cardiac failure | 51.13 | 9.77 | 146 | 148098 | 132227 | 64218261 |
Palmar-plantar erythrodysaesthesia syndrome | 51.02 | 9.77 | 4 | 148240 | 28815 | 64321673 |
Strongyloidiasis | 50.83 | 9.77 | 48 | 148196 | 3042 | 64347446 |
Actinic keratosis | 50.72 | 9.77 | 61 | 148183 | 5104 | 64345384 |
Hepatosplenomegaly | 50.68 | 9.77 | 62 | 148182 | 5281 | 64345207 |
Injection site swelling | 50.56 | 9.77 | 16 | 148228 | 41337 | 64309151 |
Lupus vasculitis | 50.46 | 9.77 | 24 | 148220 | 468 | 64350020 |
Dyskinesia | 50.42 | 9.77 | 14 | 148230 | 39374 | 64311114 |
Red blood cell sedimentation rate abnormal | 50.32 | 9.77 | 114 | 148130 | 16192 | 64334296 |
Liver transplant rejection | 50.12 | 9.77 | 47 | 148197 | 2952 | 64347536 |
Small intestinal obstruction | 49.99 | 9.77 | 143 | 148101 | 23430 | 64327058 |
Immunosuppressant drug level increased | 49.97 | 9.77 | 72 | 148172 | 7187 | 64343301 |
Autoimmune hepatitis | 49.95 | 9.77 | 86 | 148158 | 9998 | 64340490 |
Back pain | 49.45 | 9.77 | 354 | 147890 | 249817 | 64100671 |
Urinary retention | 48.89 | 9.77 | 26 | 148218 | 49175 | 64301313 |
Peliosis hepatis | 48.82 | 9.77 | 15 | 148229 | 79 | 64350409 |
Intentional self-injury | 48.81 | 9.77 | 5 | 148239 | 29039 | 64321449 |
Heart rate irregular | 48.47 | 9.77 | 156 | 148088 | 27257 | 64323231 |
Transplant dysfunction | 48.34 | 9.77 | 68 | 148176 | 6640 | 64343848 |
Retinitis | 47.56 | 9.77 | 39 | 148205 | 2046 | 64348442 |
White blood cell count decreased | 47.44 | 9.77 | 194 | 148050 | 157643 | 64192845 |
Suicide attempt | 47.34 | 9.77 | 56 | 148188 | 70951 | 64279537 |
Pneumonia cytomegaloviral | 47.19 | 9.77 | 54 | 148190 | 4285 | 64346203 |
Accidental overdose | 46.71 | 9.77 | 10 | 148234 | 33547 | 64316941 |
Mycobacterium abscessus infection | 46.45 | 9.77 | 29 | 148215 | 985 | 64349503 |
Body temperature fluctuation | 46.34 | 9.77 | 47 | 148197 | 3251 | 64347237 |
Enterocutaneous fistula | 46.13 | 9.77 | 34 | 148210 | 1523 | 64348965 |
Intentional product misuse | 46.11 | 9.77 | 59 | 148185 | 72236 | 64278252 |
Injection site erythema | 45.97 | 9.77 | 57 | 148187 | 70743 | 64279745 |
Non-cirrhotic portal hypertension | 45.87 | 9.77 | 21 | 148223 | 374 | 64350114 |
Subcutaneous abscess | 45.72 | 9.77 | 68 | 148176 | 6985 | 64343503 |
Ulcer | 45.44 | 9.77 | 136 | 148108 | 22854 | 64327634 |
Meningitis listeria | 45.39 | 9.77 | 26 | 148218 | 752 | 64349736 |
Abscess intestinal | 45.35 | 9.77 | 40 | 148204 | 2320 | 64348168 |
Nausea | 45.08 | 9.77 | 1420 | 146824 | 784380 | 63566108 |
Pyoderma gangrenosum | 44.85 | 9.77 | 45 | 148199 | 3073 | 64347415 |
Live birth | 44.68 | 9.77 | 87 | 148157 | 11117 | 64339371 |
Abdominal adhesions | 44.55 | 9.77 | 44 | 148200 | 2948 | 64347540 |
Rheumatoid factor negative | 44.45 | 9.77 | 29 | 148215 | 1064 | 64349424 |
Disseminated cytomegaloviral infection | 44.41 | 9.77 | 21 | 148223 | 404 | 64350084 |
Pleuritic pain | 44.04 | 9.77 | 72 | 148172 | 8024 | 64342464 |
Fungal endocarditis | 43.93 | 9.77 | 22 | 148222 | 482 | 64350006 |
Therapeutic reaction time decreased | 43.78 | 9.77 | 36 | 148208 | 1896 | 64348592 |
Chorioretinopathy | 43.75 | 9.77 | 38 | 148206 | 2159 | 64348329 |
Pulmonary mass | 43.67 | 9.77 | 138 | 148106 | 23878 | 64326610 |
Varicella | 43.66 | 9.77 | 41 | 148203 | 2580 | 64347908 |
Herpes simplex hepatitis | 43.49 | 9.77 | 21 | 148223 | 424 | 64350064 |
Vomiting | 43.43 | 9.77 | 951 | 147293 | 550166 | 63800322 |
Herpes zoster | 43.21 | 9.77 | 321 | 147923 | 78866 | 64271622 |
Sopor | 43.04 | 9.77 | 8 | 148236 | 29653 | 64320835 |
Abnormal behaviour | 42.94 | 9.77 | 12 | 148232 | 33610 | 64316878 |
Candida infection | 42.76 | 9.77 | 164 | 148080 | 31255 | 64319233 |
Drug level above therapeutic | 42.55 | 9.77 | 65 | 148179 | 6836 | 64343652 |
Hyperhidrosis | 42.45 | 9.77 | 146 | 148098 | 124774 | 64225714 |
Aggression | 42.29 | 9.77 | 27 | 148217 | 46205 | 64304283 |
Joint dislocation | 42.09 | 9.77 | 86 | 148158 | 11379 | 64339109 |
Joint swelling | 41.97 | 9.77 | 712 | 147532 | 214670 | 64135818 |
Angiocentric lymphoma | 41.88 | 9.77 | 25 | 148219 | 782 | 64349706 |
Intestinal perforation | 41.74 | 9.77 | 102 | 148142 | 15211 | 64335277 |
Disorientation | 41.72 | 9.77 | 40 | 148204 | 55788 | 64294700 |
Intestinal anastomosis | 41.69 | 9.77 | 21 | 148223 | 466 | 64350022 |
Rectal abscess | 41.69 | 9.77 | 32 | 148212 | 1525 | 64348963 |
Ileostomy | 41.47 | 9.77 | 29 | 148215 | 1195 | 64349293 |
Premature rupture of membranes | 41.41 | 9.77 | 47 | 148197 | 3697 | 64346791 |
Myopathy | 41.19 | 9.77 | 111 | 148133 | 17569 | 64332919 |
Abdominal abscess | 41.18 | 9.77 | 61 | 148183 | 6243 | 64344245 |
Epicondylitis | 40.92 | 9.77 | 34 | 148210 | 1817 | 64348671 |
Suicidal ideation | 40.71 | 9.77 | 56 | 148188 | 66486 | 64284002 |
Panniculitis | 40.46 | 9.77 | 73 | 148171 | 8806 | 64341682 |
Rebound effect | 40.21 | 9.77 | 53 | 148191 | 4864 | 64345624 |
Neoplasm progression | 40.18 | 9.77 | 22 | 148222 | 40942 | 64309546 |
Cytomegalovirus enteritis | 40.16 | 9.77 | 23 | 148221 | 665 | 64349823 |
Drug hypersensitivity | 39.60 | 9.77 | 767 | 147477 | 237048 | 64113440 |
Cutaneous T-cell lymphoma | 39.58 | 9.77 | 37 | 148207 | 2315 | 64348173 |
Caesarean section | 39.55 | 9.77 | 83 | 148161 | 11191 | 64339297 |
Fistula discharge | 39.37 | 9.77 | 26 | 148218 | 974 | 64349514 |
Plasma cell myeloma | 39.36 | 9.77 | 29 | 148215 | 46046 | 64304442 |
Neuroendocrine carcinoma of the skin | 39.18 | 9.77 | 26 | 148218 | 982 | 64349506 |
Complications of transplanted kidney | 39.02 | 9.77 | 55 | 148189 | 5380 | 64345108 |
Aplasia pure red cell | 39.00 | 9.77 | 63 | 148181 | 6951 | 64343537 |
Injection site pain | 38.67 | 9.77 | 129 | 148115 | 111279 | 64239209 |
Medication error | 38.28 | 9.77 | 35 | 148209 | 49931 | 64300557 |
Mucosal inflammation | 37.95 | 9.77 | 53 | 148191 | 62531 | 64287957 |
Portal hypertension | 37.54 | 9.77 | 58 | 148186 | 6161 | 64344327 |
Hypocalcaemia | 37.35 | 9.77 | 25 | 148219 | 41728 | 64308760 |
Myasthenia gravis crisis | 37.29 | 9.77 | 24 | 148220 | 860 | 64349628 |
Brain abscess | 37.22 | 9.77 | 47 | 148197 | 4134 | 64346354 |
Gastrointestinal wall thickening | 37.14 | 9.77 | 34 | 148210 | 2071 | 64348417 |
Meningitis cryptococcal | 37.12 | 9.77 | 40 | 148204 | 2969 | 64347519 |
Contraindicated product administered | 37.03 | 9.77 | 395 | 147849 | 107434 | 64243054 |
Myasthenia gravis | 36.74 | 9.77 | 55 | 148189 | 5683 | 64344805 |
Lung abscess | 36.47 | 9.77 | 43 | 148201 | 3523 | 64346965 |
Legionella infection | 36.41 | 9.77 | 22 | 148222 | 704 | 64349784 |
Poisoning | 36.17 | 9.77 | 4 | 148240 | 21875 | 64328613 |
Lymphadenitis | 36.03 | 9.77 | 44 | 148200 | 3741 | 64346747 |
Mental status changes | 35.90 | 9.77 | 53 | 148191 | 61109 | 64289379 |
C-reactive protein abnormal | 35.81 | 9.77 | 147 | 148097 | 28900 | 64321588 |
Osteonecrosis | 35.71 | 9.77 | 144 | 148100 | 28085 | 64322403 |
Ventricular tachycardia | 35.70 | 9.77 | 17 | 148227 | 34248 | 64316240 |
Pneumocystis jirovecii infection | 35.67 | 9.77 | 35 | 148209 | 2326 | 64348162 |
Pancreatitis | 35.62 | 9.77 | 247 | 147997 | 59360 | 64291128 |
Drug ineffective for unapproved indication | 35.62 | 9.77 | 154 | 148090 | 30979 | 64319509 |
Visceral leishmaniasis | 35.33 | 9.77 | 24 | 148220 | 943 | 64349545 |
Pulmonary fibrosis | 35.11 | 9.77 | 149 | 148095 | 29729 | 64320759 |
Rhegmatogenous retinal detachment | 34.96 | 9.77 | 13 | 148231 | 132 | 64350356 |
Mycobacterium avium complex infection | 34.62 | 9.77 | 44 | 148200 | 3896 | 64346592 |
Synovitis | 34.50 | 9.77 | 364 | 147880 | 98726 | 64251762 |
Glossodynia | 34.27 | 9.77 | 60 | 148184 | 64636 | 64285852 |
Restlessness | 34.04 | 9.77 | 25 | 148219 | 39760 | 64310728 |
Anaphylactic reaction | 33.93 | 9.77 | 272 | 147972 | 68392 | 64282096 |
Malignant melanoma | 33.91 | 9.77 | 85 | 148159 | 12879 | 64337609 |
Coronary artery disease | 33.91 | 9.77 | 54 | 148190 | 60379 | 64290109 |
Obliterative bronchiolitis | 33.89 | 9.77 | 36 | 148208 | 2629 | 64347859 |
Fluid retention | 33.69 | 9.77 | 53 | 148191 | 59553 | 64290935 |
Dysgeusia | 33.67 | 9.77 | 35 | 148209 | 47012 | 64303476 |
Injection site bruising | 33.60 | 9.77 | 21 | 148223 | 36352 | 64314136 |
Overlap syndrome | 33.59 | 9.77 | 21 | 148223 | 715 | 64349773 |
Eosinophilic granulomatosis with polyangiitis | 33.28 | 9.77 | 37 | 148207 | 2845 | 64347643 |
Bronchopulmonary aspergillosis | 33.19 | 9.77 | 108 | 148136 | 18977 | 64331511 |
Full blood count decreased | 32.96 | 9.77 | 6 | 148238 | 22576 | 64327912 |
Angina pectoris | 32.87 | 9.77 | 33 | 148211 | 45048 | 64305440 |
Hyperglycaemia | 32.79 | 9.77 | 56 | 148188 | 60912 | 64289576 |
Cytomegalovirus chorioretinitis | 32.77 | 9.77 | 48 | 148196 | 4864 | 64345624 |
Muscle injury | 32.73 | 9.77 | 10 | 148234 | 26427 | 64324061 |
Anti-neutrophil cytoplasmic antibody positive vasculitis | 32.71 | 9.77 | 37 | 148207 | 2899 | 64347589 |
Feeling abnormal | 32.61 | 9.77 | 177 | 148067 | 133425 | 64217063 |
Infectious mononucleosis | 32.56 | 9.77 | 29 | 148215 | 1704 | 64348784 |
Pulmonary oedema | 32.45 | 9.77 | 84 | 148160 | 78590 | 64271898 |
Phospholipidosis | 32.44 | 9.77 | 12 | 148232 | 120 | 64350368 |
Infection reactivation | 32.37 | 9.77 | 31 | 148213 | 1999 | 64348489 |
Female genital tract fistula | 32.21 | 9.77 | 35 | 148209 | 2623 | 64347865 |
Cardiac disorder | 32.15 | 9.77 | 49 | 148195 | 55767 | 64294721 |
Neutropenia | 32.11 | 9.77 | 374 | 147870 | 239250 | 64111238 |
Skin lesion | 31.93 | 9.77 | 167 | 148077 | 36315 | 64314173 |
Anorectal stenosis | 31.91 | 9.77 | 9 | 148235 | 33 | 64350455 |
Cutaneous leishmaniasis | 31.89 | 9.77 | 15 | 148229 | 285 | 64350203 |
Therapeutic product effect variable | 31.86 | 9.77 | 28 | 148216 | 1616 | 64348872 |
Pregnancy | 31.82 | 9.77 | 113 | 148131 | 20752 | 64329736 |
Natural killer-cell leukaemia | 31.36 | 9.77 | 11 | 148233 | 93 | 64350395 |
Hypomagnesaemia | 31.31 | 9.77 | 24 | 148220 | 37352 | 64313136 |
Anal cancer | 31.22 | 9.77 | 19 | 148225 | 616 | 64349872 |
Bone pain | 31.20 | 9.77 | 38 | 148206 | 47534 | 64302954 |
Gastrointestinal fistula | 31.17 | 9.77 | 19 | 148225 | 618 | 64349870 |
Cytomegalovirus test positive | 31.08 | 9.77 | 48 | 148196 | 5096 | 64345392 |
Vision blurred | 31.05 | 9.77 | 105 | 148139 | 90211 | 64260277 |
Cytomegalovirus infection reactivation | 31.05 | 9.77 | 51 | 148193 | 5705 | 64344783 |
Blood calcium decreased | 31.04 | 9.77 | 10 | 148234 | 25544 | 64324944 |
Impaired work ability | 31.00 | 9.77 | 91 | 148153 | 15128 | 64335360 |
Exostosis | 30.98 | 9.77 | 76 | 148168 | 11362 | 64339126 |
Accidental exposure to product | 30.83 | 9.77 | 11 | 148233 | 26353 | 64324135 |
Injury | 30.51 | 9.77 | 51 | 148193 | 55941 | 64294547 |
Squamous cell carcinoma of the tongue | 30.44 | 9.77 | 19 | 148225 | 645 | 64349843 |
Osteonecrosis of jaw | 30.38 | 9.77 | 28 | 148216 | 39797 | 64310691 |
Transient ischaemic attack | 30.36 | 9.77 | 34 | 148210 | 44148 | 64306340 |
Hypervolaemia | 30.31 | 9.77 | 26 | 148218 | 38259 | 64312229 |
Mycoplasma infection | 30.28 | 9.77 | 19 | 148225 | 651 | 64349837 |
Complications of transplanted lung | 30.18 | 9.77 | 16 | 148228 | 396 | 64350092 |
Cognitive disorder | 30.18 | 9.77 | 50 | 148194 | 55037 | 64295451 |
Lymphadenopathy | 30.02 | 9.77 | 197 | 148047 | 46489 | 64303999 |
Musculoskeletal stiffness | 29.99 | 9.77 | 423 | 147821 | 122783 | 64227705 |
Foetal death | 29.93 | 9.77 | 51 | 148193 | 5879 | 64344609 |
Crepitations | 29.80 | 9.77 | 60 | 148184 | 7855 | 64342633 |
Muscle fatigue | 29.77 | 9.77 | 36 | 148208 | 3029 | 64347459 |
Myelosuppression | 29.69 | 9.77 | 121 | 148123 | 23709 | 64326779 |
Proctalgia | 29.30 | 9.77 | 58 | 148186 | 7501 | 64342987 |
Listeria sepsis | 29.05 | 9.77 | 18 | 148226 | 603 | 64349885 |
Pouchitis | 29.04 | 9.77 | 20 | 148224 | 804 | 64349684 |
Irritability | 29.04 | 9.77 | 25 | 148219 | 36721 | 64313767 |
Poor venous access | 28.97 | 9.77 | 78 | 148166 | 12339 | 64338149 |
Rectal cancer metastatic | 28.89 | 9.77 | 16 | 148228 | 433 | 64350055 |
Antiphospholipid syndrome | 28.79 | 9.77 | 26 | 148218 | 1556 | 64348932 |
Lupus myocarditis | 28.78 | 9.77 | 10 | 148234 | 82 | 64350406 |
Anaemia | 28.75 | 9.77 | 657 | 147587 | 378023 | 63972465 |
Complications of bone marrow transplant | 28.68 | 9.77 | 18 | 148226 | 617 | 64349871 |
Phaeohyphomycosis | 28.59 | 9.77 | 22 | 148222 | 1052 | 64349436 |
Thrombocytopenia | 28.57 | 9.77 | 353 | 147891 | 223448 | 64127040 |
Injection site inflammation | 28.34 | 9.77 | 36 | 148208 | 3185 | 64347303 |
Autoimmune haemolytic anaemia | 28.28 | 9.77 | 55 | 148189 | 7021 | 64343467 |
Non-Hodgkin's lymphoma | 28.25 | 9.77 | 25 | 148219 | 1456 | 64349032 |
Cow pox | 28.23 | 9.77 | 8 | 148236 | 30 | 64350458 |
Neoplasm malignant | 28.15 | 9.77 | 122 | 148122 | 24566 | 64325922 |
Splenomegaly | 28.02 | 9.77 | 98 | 148146 | 17863 | 64332625 |
Rectal fissure | 27.98 | 9.77 | 19 | 148225 | 746 | 64349742 |
Multiple sclerosis relapse | 27.89 | 9.77 | 32 | 148212 | 41103 | 64309385 |
Renal mass | 27.89 | 9.77 | 33 | 148211 | 2714 | 64347774 |
Joint stiffness | 27.88 | 9.77 | 141 | 148103 | 30263 | 64320225 |
Nicotinic acid deficiency | 27.87 | 9.77 | 11 | 148233 | 133 | 64350355 |
Thiopurine methyltransferase decreased | 27.86 | 9.77 | 14 | 148230 | 309 | 64350179 |
Disturbance in attention | 27.80 | 9.77 | 32 | 148212 | 41042 | 64309446 |
Sinus bradycardia | 27.73 | 9.77 | 9 | 148235 | 22884 | 64327604 |
Nephropathy toxic | 27.70 | 9.77 | 96 | 148148 | 17418 | 64333070 |
Ganglioneuroma | 27.37 | 9.77 | 11 | 148233 | 140 | 64350348 |
Skin ulcer | 27.33 | 9.77 | 184 | 148060 | 43790 | 64306698 |
Polyomavirus-associated nephropathy | 27.31 | 9.77 | 44 | 148200 | 4844 | 64345644 |
Melaena | 27.16 | 9.77 | 51 | 148193 | 53497 | 64296991 |
Epstein Barr virus positive mucocutaneous ulcer | 27.15 | 9.77 | 18 | 148226 | 679 | 64349809 |
Intestinal anastomosis complication | 27.12 | 9.77 | 13 | 148231 | 258 | 64350230 |
Tuberculosis of central nervous system | 27.08 | 9.77 | 15 | 148229 | 406 | 64350082 |
Opportunistic infection | 27.06 | 9.77 | 32 | 148212 | 2630 | 64347858 |
Hepatitis cholestatic | 27.01 | 9.77 | 75 | 148169 | 12080 | 64338408 |
Duodenal ulcer perforation | 26.82 | 9.77 | 24 | 148220 | 34601 | 64315887 |
Foetal growth restriction | 26.80 | 9.77 | 26 | 148218 | 1704 | 64348784 |
Inappropriate antidiuretic hormone secretion | 26.58 | 9.77 | 9 | 148235 | 22280 | 64328208 |
Bronchiectasis | 26.40 | 9.77 | 82 | 148162 | 14058 | 64336430 |
Intestinal mass | 26.24 | 9.77 | 21 | 148223 | 1064 | 64349424 |
Device dislocation | 26.24 | 9.77 | 8 | 148236 | 21170 | 64329318 |
Anaplastic large cell lymphoma T- and null-cell types | 26.10 | 9.77 | 10 | 148234 | 111 | 64350377 |
Renal transplant failure | 26.07 | 9.77 | 25 | 148219 | 1615 | 64348873 |
Sepsis neonatal | 26.06 | 9.77 | 8 | 148236 | 42 | 64350446 |
Sleep disorder | 25.99 | 9.77 | 62 | 148182 | 59647 | 64290841 |
Rectal haemorrhage | 25.87 | 9.77 | 236 | 148008 | 61581 | 64288907 |
Granuloma | 25.79 | 9.77 | 51 | 148193 | 6590 | 64343898 |
Serum sickness | 25.50 | 9.77 | 34 | 148210 | 3155 | 64347333 |
Pulmonary vasculitis | 25.46 | 9.77 | 12 | 148232 | 229 | 64350259 |
Pelvic abscess | 25.39 | 9.77 | 26 | 148218 | 1819 | 64348669 |
Haematoma | 25.31 | 9.77 | 42 | 148202 | 46208 | 64304280 |
Therapy non-responder | 25.29 | 9.77 | 247 | 147997 | 65652 | 64284836 |
Blister | 25.28 | 9.77 | 98 | 148146 | 80869 | 64269619 |
Diabetic ketoacidosis | 25.21 | 9.77 | 19 | 148225 | 29826 | 64320662 |
Primary biliary cholangitis | 25.20 | 9.77 | 20 | 148224 | 1001 | 64349487 |
Lung infiltration | 25.19 | 9.77 | 105 | 148139 | 20784 | 64329704 |
Large intestinal ulcer | 25.16 | 9.77 | 39 | 148205 | 4154 | 64346334 |
Underdose | 25.15 | 9.77 | 14 | 148230 | 25815 | 64324673 |
Product quality issue | 25.14 | 9.77 | 19 | 148225 | 29780 | 64320708 |
Meningoencephalitis viral | 25.08 | 9.77 | 14 | 148230 | 385 | 64350103 |
Abdominal discomfort | 25.02 | 9.77 | 283 | 147961 | 182039 | 64168449 |
Scleroderma renal crisis | 24.98 | 9.77 | 14 | 148230 | 388 | 64350100 |
Pseudopolyp | 24.95 | 9.77 | 14 | 148230 | 389 | 64350099 |
Uveitis | 24.94 | 9.77 | 75 | 148169 | 12633 | 64337855 |
Dysarthria | 24.83 | 9.77 | 63 | 148181 | 59343 | 64291145 |
Diffuse large B-cell lymphoma stage IV | 24.82 | 9.77 | 15 | 148229 | 480 | 64350008 |
Subdural haematoma | 24.82 | 9.77 | 17 | 148227 | 28037 | 64322451 |
Muscle rigidity | 24.75 | 9.77 | 5 | 148239 | 17468 | 64333020 |
Swelling | 24.71 | 9.77 | 242 | 148002 | 159976 | 64190512 |
Rash maculo-papular | 24.56 | 9.77 | 44 | 148200 | 46982 | 64303506 |
American trypanosomiasis | 24.55 | 9.77 | 13 | 148231 | 321 | 64350167 |
Anal stenosis | 24.51 | 9.77 | 13 | 148231 | 322 | 64350166 |
Emotional distress | 24.47 | 9.77 | 28 | 148216 | 36010 | 64314478 |
Steroid dependence | 24.44 | 9.77 | 14 | 148230 | 405 | 64350083 |
Trichodysplasia spinulosa | 24.34 | 9.77 | 17 | 148227 | 699 | 64349789 |
Salmonellosis | 24.28 | 9.77 | 22 | 148222 | 1322 | 64349166 |
Leiomyosarcoma metastatic | 24.24 | 9.77 | 6 | 148238 | 11 | 64350477 |
Memory impairment | 24.08 | 9.77 | 108 | 148136 | 85574 | 64264914 |
Foot deformity | 24.00 | 9.77 | 88 | 148156 | 16416 | 64334072 |
Withdrawal syndrome | 23.95 | 9.77 | 12 | 148232 | 23480 | 64327008 |
Synovial cyst | 23.91 | 9.77 | 54 | 148190 | 7653 | 64342835 |
Bronchitis | 23.90 | 9.77 | 149 | 148095 | 108594 | 64241894 |
Pneumatosis intestinalis | 23.84 | 9.77 | 43 | 148201 | 5186 | 64345302 |
Delusion | 23.82 | 9.77 | 6 | 148238 | 18008 | 64332480 |
Acquired gene mutation | 23.80 | 9.77 | 26 | 148218 | 1960 | 64348528 |
Dementia | 23.72 | 9.77 | 9 | 148235 | 20757 | 64329731 |
Periumbilical abscess | 23.64 | 9.77 | 8 | 148236 | 60 | 64350428 |
Myasthenic syndrome | 23.55 | 9.77 | 16 | 148228 | 629 | 64349859 |
Proctocolectomy | 23.48 | 9.77 | 9 | 148235 | 100 | 64350388 |
Enteritis | 23.45 | 9.77 | 71 | 148173 | 12006 | 64338482 |
Rectal discharge | 23.42 | 9.77 | 15 | 148229 | 533 | 64349955 |
Growth retardation | 23.32 | 9.77 | 23 | 148221 | 1538 | 64348950 |
Mucous stools | 23.32 | 9.77 | 33 | 148211 | 3240 | 64347248 |
Abscess rupture | 23.20 | 9.77 | 12 | 148232 | 282 | 64350206 |
Enterostomy | 23.20 | 9.77 | 11 | 148233 | 213 | 64350275 |
Altered state of consciousness | 23.08 | 9.77 | 32 | 148212 | 37870 | 64312618 |
Antineutrophil cytoplasmic antibody increased | 22.94 | 9.77 | 9 | 148235 | 107 | 64350381 |
Tonsillar hypertrophy | 22.92 | 9.77 | 21 | 148223 | 1280 | 64349208 |
Hypersensitivity vasculitis | 22.82 | 9.77 | 49 | 148195 | 6712 | 64343776 |
Cholesteatoma | 22.79 | 9.77 | 9 | 148235 | 109 | 64350379 |
Drug tolerance | 22.76 | 9.77 | 46 | 148198 | 6039 | 64344449 |
Proctitis | 22.73 | 9.77 | 32 | 148212 | 3127 | 64347361 |
Graft versus host disease in lung | 22.57 | 9.77 | 17 | 148227 | 787 | 64349701 |
Somatic delusion | 22.57 | 9.77 | 16 | 148228 | 674 | 64349814 |
Dermatomyositis | 22.57 | 9.77 | 30 | 148214 | 2776 | 64347712 |
Chronic myeloid leukaemia | 22.55 | 9.77 | 33 | 148211 | 3341 | 64347147 |
Mydriasis | 22.50 | 9.77 | 4 | 148240 | 15308 | 64335180 |
Eye infection toxoplasmal | 22.49 | 9.77 | 14 | 148230 | 473 | 64350015 |
Neoplasm skin | 22.43 | 9.77 | 20 | 148224 | 1177 | 64349311 |
Jejunal stenosis | 22.37 | 9.77 | 8 | 148236 | 72 | 64350416 |
Drug level abnormal | 22.32 | 9.77 | 10 | 148234 | 169 | 64350319 |
Rheumatoid lung | 22.28 | 9.77 | 28 | 148216 | 2451 | 64348037 |
Asthma | 22.23 | 9.77 | 128 | 148116 | 95097 | 64255391 |
Blood sodium decreased | 22.17 | 9.77 | 21 | 148223 | 29461 | 64321027 |
Ejection fraction decreased | 22.12 | 9.77 | 20 | 148224 | 28687 | 64321801 |
Glomerulosclerosis | 21.91 | 9.77 | 18 | 148226 | 947 | 64349541 |
Pulmonary granuloma | 21.91 | 9.77 | 24 | 148220 | 1815 | 64348673 |
Helicobacter infection | 21.78 | 9.77 | 34 | 148210 | 38328 | 64312160 |
Pruritus | 21.77 | 9.77 | 549 | 147695 | 311851 | 64038637 |
Anaplastic large-cell lymphoma | 21.75 | 9.77 | 10 | 148234 | 180 | 64350308 |
Tenderness | 21.69 | 9.77 | 96 | 148148 | 19506 | 64330982 |
Gastrointestinal mucosa hyperaemia | 21.66 | 9.77 | 13 | 148231 | 411 | 64350077 |
Cytomegalovirus duodenitis | 21.62 | 9.77 | 8 | 148236 | 80 | 64350408 |
Stiff person syndrome | 21.56 | 9.77 | 11 | 148233 | 251 | 64350237 |
Arrhythmia | 21.47 | 9.77 | 57 | 148187 | 52887 | 64297601 |
Jaw fracture | 21.31 | 9.77 | 29 | 148215 | 2745 | 64347743 |
Therapy cessation | 21.25 | 9.77 | 26 | 148218 | 32463 | 64318025 |
Pulmonary nocardiosis | 21.20 | 9.77 | 16 | 148228 | 743 | 64349745 |
Intestinal mucosal hypertrophy | 21.13 | 9.77 | 11 | 148233 | 262 | 64350226 |
Dysplasia | 21.06 | 9.77 | 19 | 148225 | 1135 | 64349353 |
Device issue | 21.02 | 9.77 | 13 | 148231 | 22635 | 64327853 |
Pulmonary embolism | 20.94 | 9.77 | 225 | 148019 | 146131 | 64204357 |
Anorectal disorder | 20.87 | 9.77 | 24 | 148220 | 1915 | 64348573 |
Hepatitis viral | 20.80 | 9.77 | 17 | 148227 | 888 | 64349600 |
Chorioretinitis | 20.75 | 9.77 | 15 | 148229 | 652 | 64349836 |
Head injury | 20.73 | 9.77 | 27 | 148217 | 32815 | 64317673 |
Dyspnoea exertional | 20.68 | 9.77 | 93 | 148151 | 73637 | 64276851 |
Gait disturbance | 20.68 | 9.77 | 275 | 147969 | 171880 | 64178608 |
B-cell unclassifiable lymphoma high grade | 20.63 | 9.77 | 5 | 148239 | 8 | 64350480 |
Wrist deformity | 20.60 | 9.77 | 23 | 148221 | 1777 | 64348711 |
Tachycardia | 20.59 | 9.77 | 232 | 148012 | 149347 | 64201141 |
Injection site mass | 20.55 | 9.77 | 7 | 148237 | 17263 | 64333225 |
Rhabdomyolysis | 20.51 | 9.77 | 125 | 148119 | 91601 | 64258887 |
Drug withdrawal syndrome | 20.51 | 9.77 | 25 | 148219 | 31266 | 64319222 |
Microscopic polyangiitis | 20.47 | 9.77 | 11 | 148233 | 280 | 64350208 |
Abnormal faeces | 20.39 | 9.77 | 43 | 148201 | 5816 | 64344672 |
Blood cholesterol increased | 20.37 | 9.77 | 190 | 148054 | 49876 | 64300612 |
Small intestine carcinoma | 20.32 | 9.77 | 16 | 148228 | 792 | 64349696 |
Rectal stenosis | 20.30 | 9.77 | 11 | 148233 | 285 | 64350203 |
Anogenital warts | 20.25 | 9.77 | 16 | 148228 | 796 | 64349692 |
Cytomegalovirus syndrome | 20.23 | 9.77 | 11 | 148233 | 287 | 64350201 |
Colectomy total | 20.22 | 9.77 | 10 | 148234 | 213 | 64350275 |
Upper gastrointestinal haemorrhage | 20.20 | 9.77 | 31 | 148213 | 35189 | 64315299 |
Enterovesical fistula | 20.12 | 9.77 | 17 | 148227 | 930 | 64349558 |
Hypothyroidism | 20.11 | 9.77 | 39 | 148205 | 40418 | 64310070 |
Liver function test increased | 20.10 | 9.77 | 131 | 148113 | 30839 | 64319649 |
Wound | 19.96 | 9.77 | 99 | 148145 | 76378 | 64274110 |
Nodule | 19.93 | 9.77 | 88 | 148156 | 17859 | 64332629 |
Tonsil cancer | 19.92 | 9.77 | 17 | 148227 | 943 | 64349545 |
Extrapyramidal disorder | 19.92 | 9.77 | 10 | 148234 | 19542 | 64330946 |
Systemic lupus erythematosus | 19.91 | 9.77 | 269 | 147975 | 77343 | 64273145 |
Pollakiuria | 19.82 | 9.77 | 26 | 148218 | 31504 | 64318984 |
Hodgkin's disease | 19.75 | 9.77 | 16 | 148228 | 825 | 64349663 |
Cytomegalovirus hepatitis | 19.68 | 9.77 | 14 | 148230 | 593 | 64349895 |
Disseminated cryptococcosis | 19.63 | 9.77 | 21 | 148223 | 1546 | 64348942 |
Urinary incontinence | 19.63 | 9.77 | 33 | 148211 | 36118 | 64314370 |
Cervical dysplasia | 19.62 | 9.77 | 23 | 148221 | 1873 | 64348615 |
Peritoneal tuberculosis | 19.55 | 9.77 | 13 | 148231 | 493 | 64349995 |
Drug resistance | 19.54 | 9.77 | 143 | 148101 | 34959 | 64315529 |
Chronic hepatitis | 19.54 | 9.77 | 19 | 148225 | 1249 | 64349239 |
Gestational diabetes | 19.43 | 9.77 | 41 | 148203 | 5549 | 64344939 |
Food intolerance | 19.41 | 9.77 | 28 | 148216 | 2798 | 64347690 |
Chronic gastrointestinal bleeding | 19.39 | 9.77 | 12 | 148232 | 401 | 64350087 |
Porokeratosis | 19.37 | 9.77 | 10 | 148234 | 234 | 64350254 |
Granuloma skin | 19.34 | 9.77 | 43 | 148201 | 6031 | 64344457 |
Autoimmune neutropenia | 19.26 | 9.77 | 12 | 148232 | 406 | 64350082 |
Premature separation of placenta | 19.26 | 9.77 | 18 | 148226 | 1126 | 64349362 |
Intestinal fibrosis | 19.22 | 9.77 | 8 | 148236 | 112 | 64350376 |
Graft loss | 19.21 | 9.77 | 17 | 148227 | 990 | 64349498 |
Peripheral T-cell lymphoma unspecified stage IV | 19.16 | 9.77 | 6 | 148238 | 34 | 64350454 |
Pancreatitis acute | 19.16 | 9.77 | 166 | 148078 | 42689 | 64307799 |
Carcinoid tumour pulmonary | 19.08 | 9.77 | 11 | 148233 | 322 | 64350166 |
Trichostasis spinulosa | 19.01 | 9.77 | 5 | 148239 | 13 | 64350475 |
Hyperthyroidism | 18.97 | 9.77 | 9 | 148235 | 18170 | 64332318 |
Palatal ulcer | 18.96 | 9.77 | 8 | 148236 | 116 | 64350372 |
Electrolyte imbalance | 18.96 | 9.77 | 18 | 148226 | 25225 | 64325263 |
Hypophagia | 18.96 | 9.77 | 39 | 148205 | 39548 | 64310940 |
Epstein-Barr viraemia | 18.93 | 9.77 | 22 | 148222 | 1775 | 64348713 |
Necrotising herpetic retinopathy | 18.90 | 9.77 | 8 | 148236 | 117 | 64350371 |
Joint effusion | 18.89 | 9.77 | 71 | 148173 | 13402 | 64337086 |
Splenic embolism | 18.76 | 9.77 | 9 | 148235 | 179 | 64350309 |
Myoclonus | 18.76 | 9.77 | 18 | 148226 | 25100 | 64325388 |
Polyhydramnios | 18.75 | 9.77 | 20 | 148224 | 1467 | 64349021 |
Dyspepsia | 18.72 | 9.77 | 108 | 148136 | 80204 | 64270284 |
Creatinine renal clearance decreased | 18.69 | 9.77 | 5 | 148239 | 14416 | 64336072 |
Urticaria | 18.69 | 9.77 | 457 | 147787 | 146860 | 64203628 |
Femur fracture | 18.68 | 9.77 | 31 | 148213 | 34104 | 64316384 |
Brain stem syndrome | 18.66 | 9.77 | 15 | 148229 | 765 | 64349723 |
Leiomyosarcoma | 18.56 | 9.77 | 10 | 148234 | 256 | 64350232 |
Angioedema | 18.55 | 9.77 | 76 | 148168 | 61745 | 64288743 |
Intestinal ulcer | 18.52 | 9.77 | 21 | 148223 | 1650 | 64348838 |
Paracoccidioides infection | 18.49 | 9.77 | 7 | 148237 | 75 | 64350413 |
Cryptococcosis | 18.49 | 9.77 | 27 | 148217 | 2728 | 64347760 |
Hip fracture | 18.46 | 9.77 | 21 | 148223 | 27078 | 64323410 |
Necrotising retinitis | 18.42 | 9.77 | 17 | 148227 | 1046 | 64349442 |
Henoch-Schonlein purpura | 18.38 | 9.77 | 24 | 148220 | 2182 | 64348306 |
Paraesthesia | 18.37 | 9.77 | 209 | 148035 | 134313 | 64216175 |
Bacillary angiomatosis | 18.36 | 9.77 | 9 | 148235 | 188 | 64350300 |
Pyrexia | 18.34 | 9.77 | 1506 | 146738 | 557138 | 63793350 |
Vasculitis necrotising | 18.30 | 9.77 | 17 | 148227 | 1055 | 64349433 |
Eye ulcer | 18.21 | 9.77 | 10 | 148234 | 266 | 64350222 |
Transient hypogammaglobulinaemia of infancy | 18.21 | 9.77 | 6 | 148238 | 41 | 64350447 |
Product administration error | 18.21 | 9.77 | 22 | 148222 | 27621 | 64322867 |
Hospitalisation | 18.15 | 9.77 | 100 | 148144 | 75107 | 64275381 |
Oesophageal squamous cell carcinoma | 18.00 | 9.77 | 12 | 148232 | 457 | 64350031 |
Oral pain | 17.98 | 9.77 | 22 | 148222 | 27471 | 64323017 |
Lymph node tuberculosis | 17.96 | 9.77 | 16 | 148228 | 940 | 64349548 |
Mouth ulceration | 17.96 | 9.77 | 132 | 148112 | 32312 | 64318176 |
Blood glucose decreased | 17.94 | 9.77 | 16 | 148228 | 23107 | 64327381 |
Blood parathyroid hormone decreased | 17.92 | 9.77 | 47 | 148197 | 7319 | 64343169 |
HELLP syndrome | 17.92 | 9.77 | 14 | 148230 | 685 | 64349803 |
Lymphocytic infiltration | 17.91 | 9.77 | 19 | 148225 | 1385 | 64349103 |
Dry skin | 17.91 | 9.77 | 59 | 148185 | 51102 | 64299386 |
Disease progression | 17.87 | 9.77 | 224 | 148020 | 141456 | 64209032 |
Tractional retinal detachment | 17.86 | 9.77 | 7 | 148237 | 83 | 64350405 |
Weber tuning fork test abnormal | 17.78 | 9.77 | 7 | 148237 | 84 | 64350404 |
Irritable bowel syndrome | 17.74 | 9.77 | 37 | 148207 | 37332 | 64313156 |
Cystitis escherichia | 17.72 | 9.77 | 12 | 148232 | 469 | 64350019 |
Faecal calprotectin abnormal | 17.71 | 9.77 | 8 | 148236 | 138 | 64350350 |
Flank pain | 17.69 | 9.77 | 79 | 148165 | 16110 | 64334378 |
Gastrointestinal obstruction | 17.68 | 9.77 | 19 | 148225 | 1406 | 64349082 |
Antisynthetase syndrome | 17.65 | 9.77 | 8 | 148236 | 139 | 64350349 |
Burkitt's lymphoma stage III | 17.59 | 9.77 | 5 | 148239 | 19 | 64350469 |
Hepatitis | 17.56 | 9.77 | 171 | 148073 | 45411 | 64305077 |
Pseudoxanthoma elasticum-like syndrome | 17.55 | 9.77 | 4 | 148240 | 4 | 64350484 |
Depressed mood | 17.52 | 9.77 | 43 | 148201 | 40969 | 64309519 |
Infective pulmonary exacerbation of cystic fibrosis | 17.51 | 9.77 | 3 | 148241 | 11793 | 64338695 |
Gastrointestinal stoma output abnormal | 17.50 | 9.77 | 6 | 148238 | 47 | 64350441 |
Neuromyelitis optica spectrum disorder | 17.42 | 9.77 | 15 | 148229 | 842 | 64349646 |
Amnesia | 17.36 | 9.77 | 55 | 148189 | 48214 | 64302274 |
Dermatitis psoriasiform | 17.35 | 9.77 | 23 | 148221 | 2123 | 64348365 |
Retinal scar | 17.32 | 9.77 | 11 | 148233 | 385 | 64350103 |
Ileal ulcer | 17.24 | 9.77 | 16 | 148228 | 992 | 64349496 |
Viral test positive | 17.22 | 9.77 | 11 | 148233 | 389 | 64350099 |
Laparotomy | 17.22 | 9.77 | 10 | 148234 | 297 | 64350191 |
Gastrooesophageal reflux disease | 17.21 | 9.77 | 116 | 148128 | 83027 | 64267461 |
Appendicectomy | 17.20 | 9.77 | 23 | 148221 | 2140 | 64348348 |
Anastomotic complication | 17.20 | 9.77 | 11 | 148233 | 390 | 64350098 |
Acne conglobata | 17.19 | 9.77 | 5 | 148239 | 21 | 64350467 |
Lung neoplasm | 17.19 | 9.77 | 42 | 148202 | 6263 | 64344225 |
Epistaxis | 17.16 | 9.77 | 319 | 147925 | 97812 | 64252676 |
Muscle spasms | 17.15 | 9.77 | 435 | 147809 | 140588 | 64209900 |
Focal segmental glomerulosclerosis | 17.13 | 9.77 | 27 | 148217 | 2917 | 64347571 |
Conjunctivitis | 17.01 | 9.77 | 92 | 148152 | 20262 | 64330226 |
Optic neuritis | 16.98 | 9.77 | 49 | 148195 | 8067 | 64342421 |
Nightmare | 16.93 | 9.77 | 14 | 148230 | 20979 | 64329509 |
Infertility | 16.83 | 9.77 | 12 | 148232 | 510 | 64349978 |
Respiratory gas exchange disorder | 16.81 | 9.77 | 14 | 148230 | 751 | 64349737 |
Aspergillosis oral | 16.78 | 9.77 | 6 | 148238 | 54 | 64350434 |
Laryngeal disorder | 16.76 | 9.77 | 15 | 148229 | 887 | 64349601 |
Gastrointestinal stoma complication | 16.69 | 9.77 | 23 | 148221 | 2203 | 64348285 |
Cytokine release syndrome | 16.66 | 9.77 | 14 | 148230 | 20815 | 64329673 |
Hodgkin's disease nodular sclerosis | 16.66 | 9.77 | 5 | 148239 | 24 | 64350464 |
Headache | 16.65 | 9.77 | 1022 | 147222 | 528445 | 63822043 |
Therapy interrupted | 16.61 | 9.77 | 13 | 148231 | 20023 | 64330465 |
Encephalopathy | 16.61 | 9.77 | 74 | 148170 | 58745 | 64291743 |
Haematemesis | 16.59 | 9.77 | 54 | 148190 | 46945 | 64303543 |
Testicular cancer metastatic | 16.58 | 9.77 | 6 | 148238 | 56 | 64350432 |
Malignant polyp | 16.54 | 9.77 | 8 | 148236 | 162 | 64350326 |
Fistula of small intestine | 16.53 | 9.77 | 13 | 148231 | 642 | 64349846 |
Haemophilus infection | 16.48 | 9.77 | 21 | 148223 | 1864 | 64348624 |
Hypergammaglobulinaemia | 16.46 | 9.77 | 13 | 148231 | 646 | 64349842 |
Pneumonia legionella | 16.46 | 9.77 | 24 | 148220 | 2422 | 64348066 |
Hepatic enzyme increased | 16.45 | 9.77 | 403 | 147841 | 129540 | 64220948 |
Pseudomonas infection | 16.44 | 9.77 | 83 | 148161 | 17800 | 64332688 |
Ileectomy | 16.41 | 9.77 | 8 | 148236 | 165 | 64350323 |
Febrile bone marrow aplasia | 16.41 | 9.77 | 3 | 148241 | 11252 | 64339236 |
Chest discomfort | 16.40 | 9.77 | 179 | 148065 | 115927 | 64234561 |
Intestinal dilatation | 16.39 | 9.77 | 23 | 148221 | 2241 | 64348247 |
Marrow hyperplasia | 16.38 | 9.77 | 18 | 148226 | 1366 | 64349122 |
Mycetoma mycotic | 16.38 | 9.77 | 7 | 148237 | 105 | 64350383 |
Ventricular extrasystoles | 16.36 | 9.77 | 10 | 148234 | 17519 | 64332969 |
Cardiogenic shock | 16.34 | 9.77 | 31 | 148213 | 32396 | 64318092 |
Mucocutaneous leishmaniasis | 16.31 | 9.77 | 11 | 148233 | 427 | 64350061 |
Muscle spasticity | 16.28 | 9.77 | 9 | 148235 | 16660 | 64333828 |
Renal impairment | 16.28 | 9.77 | 416 | 147828 | 134601 | 64215887 |
Ischaemic stroke | 16.23 | 9.77 | 26 | 148218 | 29009 | 64321479 |
Narcotic bowel syndrome | 16.20 | 9.77 | 9 | 148235 | 245 | 64350243 |
Stevens-Johnson syndrome | 16.18 | 9.77 | 34 | 148210 | 34215 | 64316273 |
Neutrophilic dermatosis | 16.17 | 9.77 | 12 | 148232 | 543 | 64349945 |
Discomfort | 16.17 | 9.77 | 114 | 148130 | 80764 | 64269724 |
Systemic candida | 16.16 | 9.77 | 37 | 148207 | 5292 | 64345196 |
Herpes zoster meningoencephalitis | 15.94 | 9.77 | 13 | 148231 | 677 | 64349811 |
Skin cancer | 15.88 | 9.77 | 62 | 148182 | 11912 | 64338576 |
Sebaceous carcinoma | 15.80 | 9.77 | 7 | 148237 | 115 | 64350373 |
Corynebacterium infection | 15.79 | 9.77 | 15 | 148229 | 958 | 64349530 |
Ventricular fibrillation | 15.71 | 9.77 | 19 | 148225 | 23841 | 64326647 |
Skin papilloma | 15.64 | 9.77 | 36 | 148208 | 5167 | 64345321 |
Fear | 15.60 | 9.77 | 14 | 148230 | 20157 | 64330331 |
Exercise tolerance increased | 15.59 | 9.77 | 5 | 148239 | 31 | 64350457 |
Stress at work | 15.58 | 9.77 | 15 | 148229 | 974 | 64349514 |
Anal skin tags | 15.55 | 9.77 | 10 | 148234 | 358 | 64350130 |
Troponin increased | 15.50 | 9.77 | 8 | 148236 | 15391 | 64335097 |
Cardiac valve vegetation | 15.48 | 9.77 | 14 | 148230 | 839 | 64349649 |
Hepatitis B | 15.48 | 9.77 | 46 | 148198 | 7699 | 64342789 |
DNA antibody | 15.46 | 9.77 | 5 | 148239 | 32 | 64350456 |
Eosinophilic bronchitis | 15.37 | 9.77 | 10 | 148234 | 365 | 64350123 |
Hallucination, auditory | 15.34 | 9.77 | 10 | 148234 | 16929 | 64333559 |
Bowel movement irregularity | 15.34 | 9.77 | 34 | 148210 | 4759 | 64345729 |
Blood bilirubin increased | 15.31 | 9.77 | 74 | 148170 | 57479 | 64293009 |
Anaphylactic shock | 15.28 | 9.77 | 29 | 148215 | 30299 | 64320189 |
Blood potassium decreased | 15.27 | 9.77 | 45 | 148199 | 40354 | 64310134 |
Laryngeal mass | 15.24 | 9.77 | 6 | 148238 | 72 | 64350416 |
Herpes simplex test positive | 15.23 | 9.77 | 10 | 148234 | 371 | 64350117 |
Sleep disorder due to general medical condition, insomnia type | 15.19 | 9.77 | 23 | 148221 | 26247 | 64324241 |
Herpes simplex | 15.17 | 9.77 | 56 | 148188 | 10480 | 64340008 |
Epstein-Barr virus antibody positive | 15.15 | 9.77 | 12 | 148232 | 599 | 64349889 |
Acinetobacter infection | 15.15 | 9.77 | 23 | 148221 | 2406 | 64348082 |
Human ehrlichiosis | 15.13 | 9.77 | 10 | 148234 | 375 | 64350113 |
Injection site pruritus | 15.13 | 9.77 | 41 | 148203 | 37785 | 64312703 |
Mycobacterium kansasii infection | 15.12 | 9.77 | 9 | 148235 | 280 | 64350208 |
Mucormycosis | 15.05 | 9.77 | 44 | 148200 | 7297 | 64343191 |
Pyometra | 15.02 | 9.77 | 6 | 148238 | 75 | 64350413 |
Heart rate decreased | 15.01 | 9.77 | 193 | 148051 | 54874 | 64295614 |
Anaemia macrocytic | 14.99 | 9.77 | 32 | 148212 | 4366 | 64346122 |
Folliculitis | 14.94 | 9.77 | 29 | 148215 | 30048 | 64320440 |
Hypoxia | 14.94 | 9.77 | 130 | 148114 | 88019 | 64262469 |
Retinal injury | 14.89 | 9.77 | 9 | 148235 | 288 | 64350200 |
Ileal perforation | 14.89 | 9.77 | 14 | 148230 | 882 | 64349606 |
Product storage error | 14.84 | 9.77 | 6 | 148238 | 13312 | 64337176 |
Tinea capitis | 14.79 | 9.77 | 4 | 148240 | 12 | 64350476 |
Placental necrosis | 14.79 | 9.77 | 4 | 148240 | 12 | 64350476 |
Torsade de pointes | 14.74 | 9.77 | 11 | 148233 | 17352 | 64333136 |
Obstructive airways disorder | 14.70 | 9.77 | 19 | 148225 | 23166 | 64327322 |
Haematocrit decreased | 14.70 | 9.77 | 70 | 148174 | 54585 | 64295903 |
Anger | 14.66 | 9.77 | 9 | 148235 | 15732 | 64334756 |
Drug specific antibody absent | 14.60 | 9.77 | 7 | 148237 | 139 | 64350349 |
Hallucination, visual | 14.57 | 9.77 | 26 | 148218 | 27808 | 64322680 |
Listeria encephalitis | 14.57 | 9.77 | 9 | 148235 | 300 | 64350188 |
Mitochondrial neurogastrointestinal encephalopathy | 14.55 | 9.77 | 4 | 148240 | 13 | 64350475 |
Glomerulonephritis | 14.54 | 9.77 | 25 | 148219 | 2903 | 64347585 |
Pneumonia cryptococcal | 14.47 | 9.77 | 16 | 148228 | 1223 | 64349265 |
Hidradenitis | 14.45 | 9.77 | 22 | 148222 | 2307 | 64348181 |
Oxygen saturation decreased | 14.44 | 9.77 | 167 | 148077 | 107009 | 64243479 |
Meningitis aseptic | 14.39 | 9.77 | 37 | 148207 | 5693 | 64344795 |
Gastrointestinal oedema | 14.37 | 9.77 | 22 | 148222 | 2318 | 64348170 |
Complications of transplanted heart | 14.35 | 9.77 | 9 | 148235 | 308 | 64350180 |
Proctectomy | 14.35 | 9.77 | 6 | 148238 | 85 | 64350403 |
Atrial flutter | 14.34 | 9.77 | 14 | 148230 | 19366 | 64331122 |
Joint tuberculosis | 14.33 | 9.77 | 7 | 148237 | 145 | 64350343 |
Respiratory tract infection fungal | 14.33 | 9.77 | 15 | 148229 | 1077 | 64349411 |
Hand deformity | 14.32 | 9.77 | 85 | 148159 | 62686 | 64287802 |
Pharyngeal oedema | 14.30 | 9.77 | 9 | 148235 | 15522 | 64334966 |
Chest pain | 14.27 | 9.77 | 423 | 147821 | 235557 | 64114931 |
Night sweats | 14.27 | 9.77 | 136 | 148108 | 35910 | 64314578 |
Salivary hypersecretion | 14.26 | 9.77 | 5 | 148239 | 12108 | 64338380 |
Skin necrosis | 14.24 | 9.77 | 68 | 148176 | 14261 | 64336227 |
Cough | 14.23 | 9.77 | 559 | 147685 | 301589 | 64048899 |
Toxic skin eruption | 14.19 | 9.77 | 14 | 148230 | 19270 | 64331218 |
Angina unstable | 14.19 | 9.77 | 9 | 148235 | 15458 | 64335030 |
Lethargy | 14.18 | 9.77 | 103 | 148141 | 72491 | 64277997 |
Primary effusion lymphoma | 14.18 | 9.77 | 5 | 148239 | 43 | 64350445 |
Tuberous sclerosis complex | 14.16 | 9.77 | 6 | 148238 | 88 | 64350400 |
Aspartate aminotransferase increased | 14.14 | 9.77 | 192 | 148052 | 119596 | 64230892 |
Tricuspid valve incompetence | 14.14 | 9.77 | 11 | 148233 | 16992 | 64333496 |
Diffuse large B-cell lymphoma stage III | 14.10 | 9.77 | 6 | 148238 | 89 | 64350399 |
Intestinal operation | 14.09 | 9.77 | 10 | 148234 | 422 | 64350066 |
Sideroblastic anaemia | 14.04 | 9.77 | 8 | 148236 | 229 | 64350259 |
Oral lichen planus | 14.01 | 9.77 | 12 | 148232 | 669 | 64349819 |
Palpitations | 14.01 | 9.77 | 163 | 148081 | 104325 | 64246163 |
Perirectal abscess | 14.00 | 9.77 | 19 | 148225 | 1794 | 64348694 |
Necrosis | 13.99 | 9.77 | 46 | 148198 | 8125 | 64342363 |
Rectal cancer | 13.99 | 9.77 | 24 | 148220 | 2782 | 64347706 |
Fungal peritonitis | 13.94 | 9.77 | 14 | 148230 | 957 | 64349531 |
Whipple's disease | 13.91 | 9.77 | 4 | 148240 | 16 | 64350472 |
Ureteral neoplasm | 13.91 | 9.77 | 4 | 148240 | 16 | 64350472 |
Pulmonary paracoccidioidomycosis | 13.91 | 9.77 | 4 | 148240 | 16 | 64350472 |
Tenosynovitis | 13.89 | 9.77 | 59 | 148185 | 11774 | 64338714 |
Failed induction of labour | 13.89 | 9.77 | 8 | 148236 | 234 | 64350254 |
Gastrointestinal scarring | 13.89 | 9.77 | 8 | 148236 | 234 | 64350254 |
Blood potassium increased | 13.84 | 9.77 | 24 | 148220 | 25956 | 64324532 |
Adverse reaction | 13.82 | 9.77 | 44 | 148200 | 7643 | 64342845 |
Dysphagia | 13.79 | 9.77 | 168 | 148076 | 106644 | 64243844 |
Anal squamous cell carcinoma | 13.72 | 9.77 | 10 | 148234 | 440 | 64350048 |
Retinal vasculitis | 13.72 | 9.77 | 15 | 148229 | 1132 | 64349356 |
Pulmonary congestion | 13.71 | 9.77 | 21 | 148223 | 23859 | 64326629 |
Cervix carcinoma | 13.71 | 9.77 | 19 | 148225 | 1829 | 64348659 |
Parkinsonism | 13.69 | 9.77 | 8 | 148236 | 14365 | 64336123 |
Rhinitis | 13.68 | 9.77 | 55 | 148189 | 10710 | 64339778 |
Toxic epidermal necrolysis | 13.61 | 9.77 | 42 | 148202 | 37124 | 64313364 |
Polyuria | 13.60 | 9.77 | 6 | 148238 | 12637 | 64337851 |
Drug withdrawal syndrome neonatal | 13.58 | 9.77 | 8 | 148236 | 244 | 64350244 |
Skin exfoliation | 13.58 | 9.77 | 55 | 148189 | 44830 | 64305658 |
Throat cancer | 13.54 | 9.77 | 14 | 148230 | 991 | 64349497 |
Foetal exposure during pregnancy | 13.48 | 9.77 | 31 | 148213 | 4445 | 64346043 |
Oesophagitis | 13.43 | 9.77 | 18 | 148226 | 21612 | 64328876 |
Acne | 13.41 | 9.77 | 95 | 148149 | 22986 | 64327502 |
Transplant failure | 13.39 | 9.77 | 28 | 148216 | 3766 | 64346722 |
Butterfly rash | 13.35 | 9.77 | 15 | 148229 | 1167 | 64349321 |
Anovulatory cycle | 13.31 | 9.77 | 6 | 148238 | 103 | 64350385 |
Drug specific antibody | 13.30 | 9.77 | 20 | 148224 | 2075 | 64348413 |
Anastomotic stenosis | 13.26 | 9.77 | 10 | 148234 | 464 | 64350024 |
Oesophagopleural fistula | 13.26 | 9.77 | 5 | 148239 | 53 | 64350435 |
Thinking abnormal | 13.21 | 9.77 | 5 | 148239 | 11551 | 64338937 |
Peritoneal candidiasis | 13.19 | 9.77 | 4 | 148240 | 20 | 64350468 |
Skin hyperpigmentation | 13.18 | 9.77 | 39 | 148205 | 6512 | 64343976 |
Enterostomy closure | 13.16 | 9.77 | 3 | 148241 | 3 | 64350485 |
Antineutrophil cytoplasmic antibody decreased | 13.16 | 9.77 | 3 | 148241 | 3 | 64350485 |
Precursor T-lymphoblastic lymphoma/leukaemia stage I | 13.16 | 9.77 | 3 | 148241 | 3 | 64350485 |
Faecaluria | 13.16 | 9.77 | 3 | 148241 | 3 | 64350485 |
Swollen tongue | 13.16 | 9.77 | 39 | 148205 | 34915 | 64315573 |
Mediastinal effusion | 13.09 | 9.77 | 5 | 148239 | 55 | 64350433 |
Small intestinal resection | 13.09 | 9.77 | 12 | 148232 | 732 | 64349756 |
Hepatic fibrosis | 13.08 | 9.77 | 35 | 148209 | 5517 | 64344971 |
Skin mass | 13.07 | 9.77 | 41 | 148203 | 7065 | 64343423 |
Trichosporon infection | 13.06 | 9.77 | 13 | 148231 | 879 | 64349609 |
Immunodeficiency common variable | 13.05 | 9.77 | 8 | 148236 | 263 | 64350225 |
Metastatic malignant melanoma | 13.02 | 9.77 | 22 | 148222 | 2519 | 64347969 |
Varicella zoster pneumonia | 13.00 | 9.77 | 6 | 148238 | 109 | 64350379 |
Mycobacterium chelonae infection | 13.00 | 9.77 | 20 | 148224 | 2117 | 64348371 |
Ear infection | 12.83 | 9.77 | 95 | 148149 | 23309 | 64327179 |
Acute respiratory failure | 12.82 | 9.77 | 65 | 148179 | 49869 | 64300619 |
Renal injury | 12.81 | 9.77 | 10 | 148234 | 15419 | 64335069 |
Rectal tenesmus | 12.78 | 9.77 | 14 | 148230 | 1059 | 64349429 |
Small intestinal perforation | 12.77 | 9.77 | 22 | 148222 | 2558 | 64347930 |
Aspiration | 12.73 | 9.77 | 12 | 148232 | 16873 | 64333615 |
Femoral artery aneurysm | 12.72 | 9.77 | 7 | 148237 | 187 | 64350301 |
Peripheral artery aneurysm | 12.68 | 9.77 | 9 | 148235 | 380 | 64350108 |
Adenocarcinoma of colon | 12.65 | 9.77 | 32 | 148212 | 4876 | 64345612 |
Gastroenterostomy | 12.63 | 9.77 | 5 | 148239 | 61 | 64350427 |
Foetal malpresentation | 12.63 | 9.77 | 5 | 148239 | 61 | 64350427 |
Deep vein thrombosis | 12.63 | 9.77 | 168 | 148076 | 105014 | 64245474 |
Nervousness | 12.62 | 9.77 | 31 | 148213 | 29525 | 64320963 |
Skin striae | 12.61 | 9.77 | 16 | 148228 | 1414 | 64349074 |
Abdominal pain upper | 12.60 | 9.77 | 306 | 147938 | 174724 | 64175764 |
Laser therapy | 12.58 | 9.77 | 4 | 148240 | 24 | 64350464 |
Hot flush | 12.56 | 9.77 | 59 | 148185 | 46176 | 64304312 |
Impetigo | 12.56 | 9.77 | 18 | 148226 | 1788 | 64348700 |
Premature baby | 12.55 | 9.77 | 25 | 148219 | 3247 | 64347241 |
DNA antibody positive | 12.52 | 9.77 | 8 | 148236 | 283 | 64350205 |
Myelitis transverse | 12.52 | 9.77 | 17 | 148227 | 1606 | 64348882 |
Ocular toxicity | 12.51 | 9.77 | 11 | 148233 | 635 | 64349853 |
Cardiotoxicity | 12.51 | 9.77 | 4 | 148240 | 10270 | 64340218 |
Blood creatine phosphokinase increased | 12.47 | 9.77 | 81 | 148163 | 58477 | 64292011 |
Hyperlipidaemia | 12.45 | 9.77 | 21 | 148223 | 22955 | 64327533 |
Burkitt's lymphoma | 12.43 | 9.77 | 6 | 148238 | 121 | 64350367 |
Needle issue | 12.43 | 9.77 | 3 | 148241 | 9269 | 64341219 |
Injection site haemorrhage | 12.42 | 9.77 | 23 | 148221 | 24255 | 64326233 |
Gastrointestinal ulcer | 12.41 | 9.77 | 24 | 148220 | 3051 | 64347437 |
Anal ulcer | 12.40 | 9.77 | 14 | 148230 | 1095 | 64349393 |
Herpes virus infection | 12.40 | 9.77 | 37 | 148207 | 6207 | 64344281 |
Graft complication | 12.37 | 9.77 | 11 | 148233 | 645 | 64349843 |
Pseudopolyposis | 12.34 | 9.77 | 5 | 148239 | 65 | 64350423 |
Renal cell carcinoma stage III | 12.31 | 9.77 | 4 | 148240 | 26 | 64350462 |
Gastrointestinal dilation procedure | 12.30 | 9.77 | 3 | 148241 | 5 | 64350483 |
Pulmonary function test increased | 12.30 | 9.77 | 3 | 148241 | 5 | 64350483 |
Diaphragmatic injury | 12.30 | 9.77 | 6 | 148238 | 124 | 64350364 |
Kidney fibrosis | 12.27 | 9.77 | 24 | 148220 | 3077 | 64347411 |
Mycoplasma test positive | 12.23 | 9.77 | 7 | 148237 | 202 | 64350286 |
Cyanosis | 12.23 | 9.77 | 20 | 148224 | 22135 | 64328353 |
Adjustment disorder with depressed mood | 12.23 | 9.77 | 21 | 148223 | 2436 | 64348052 |
Blood urea increased | 12.20 | 9.77 | 56 | 148188 | 44097 | 64306391 |
Sleep apnoea syndrome | 12.19 | 9.77 | 32 | 148212 | 29800 | 64320688 |
Haemolysis | 12.16 | 9.77 | 54 | 148190 | 10985 | 64339503 |
Rash pustular | 12.16 | 9.77 | 50 | 148194 | 9835 | 64340653 |
Cutaneous lupus erythematosus | 12.16 | 9.77 | 22 | 148222 | 2660 | 64347828 |
Electrocardiogram abnormal | 12.15 | 9.77 | 8 | 148236 | 13473 | 64337015 |
Pneumonitis | 12.13 | 9.77 | 67 | 148177 | 50298 | 64300190 |
Dysphonia | 12.13 | 9.77 | 60 | 148184 | 46322 | 64304166 |
Hirsutism | 12.12 | 9.77 | 13 | 148231 | 960 | 64349528 |
Atypical mycobacterial infection | 12.12 | 9.77 | 15 | 148229 | 1293 | 64349195 |
Iron deficiency anaemia | 12.08 | 9.77 | 89 | 148155 | 21800 | 64328688 |
Deafness transitory | 12.06 | 9.77 | 12 | 148232 | 811 | 64349677 |
Acute coronary syndrome | 12.06 | 9.77 | 16 | 148228 | 19294 | 64331194 |
Herpes simplex colitis | 12.06 | 9.77 | 4 | 148240 | 28 | 64350460 |
Transaminases increased | 12.03 | 9.77 | 156 | 148088 | 44438 | 64306050 |
Psychotic disorder | 12.02 | 9.77 | 40 | 148204 | 34538 | 64315950 |
Diabetes mellitus inadequate control | 12.01 | 9.77 | 19 | 148225 | 21302 | 64329186 |
Infective tenosynovitis | 11.99 | 9.77 | 8 | 148236 | 305 | 64350183 |
Cerebral infarction | 11.98 | 9.77 | 51 | 148193 | 40993 | 64309495 |
Anaplastic large cell lymphoma T- and null-cell types stage III | 11.95 | 9.77 | 3 | 148241 | 6 | 64350482 |
Actinic cheilitis | 11.95 | 9.77 | 3 | 148241 | 6 | 64350482 |
Cryoglobulins present | 11.95 | 9.77 | 3 | 148241 | 6 | 64350482 |
Cholangitis chronic | 11.94 | 9.77 | 4 | 148240 | 29 | 64350459 |
Peripheral swelling | 11.89 | 9.77 | 378 | 147866 | 208775 | 64141713 |
Epstein-Barr virus infection reactivation | 11.83 | 9.77 | 14 | 148230 | 1152 | 64349336 |
Subarachnoid haemorrhage | 11.80 | 9.77 | 15 | 148229 | 18423 | 64332065 |
Vascular graft complication | 11.80 | 9.77 | 6 | 148238 | 136 | 64350352 |
Gingival hypertrophy | 11.78 | 9.77 | 22 | 148222 | 2725 | 64347763 |
Faeces discoloured | 11.77 | 9.77 | 26 | 148218 | 25703 | 64324785 |
Thrombotic microangiopathy | 11.77 | 9.77 | 72 | 148172 | 16583 | 64333905 |
Renal tubular atrophy | 11.77 | 9.77 | 16 | 148228 | 1513 | 64348975 |
Injection site induration | 11.76 | 9.77 | 3 | 148241 | 8929 | 64341559 |
Enterocolonic fistula | 11.76 | 9.77 | 6 | 148238 | 137 | 64350351 |
Arteriosclerosis coronary artery | 11.75 | 9.77 | 11 | 148233 | 15518 | 64334970 |
Pyoderma | 11.74 | 9.77 | 8 | 148236 | 316 | 64350172 |
Ileostomy closure | 11.72 | 9.77 | 6 | 148238 | 138 | 64350350 |
Vitamin B1 decreased | 11.72 | 9.77 | 8 | 148236 | 317 | 64350171 |
Eosinophilic myocarditis | 11.71 | 9.77 | 12 | 148232 | 840 | 64349648 |
Threatened labour | 11.71 | 9.77 | 10 | 148234 | 555 | 64349933 |
Cytopenia | 11.65 | 9.77 | 68 | 148176 | 15403 | 64335085 |
Spindle cell sarcoma | 11.64 | 9.77 | 7 | 148237 | 222 | 64350266 |
Paradoxical psoriasis | 11.60 | 9.77 | 6 | 148238 | 141 | 64350347 |
Metastases to central nervous system | 11.57 | 9.77 | 9 | 148235 | 13903 | 64336585 |
Second primary malignancy | 11.57 | 9.77 | 7 | 148237 | 12330 | 64338158 |
Abdominal pain lower | 11.55 | 9.77 | 102 | 148142 | 26367 | 64324121 |
Gastrointestinal motility disorder | 11.55 | 9.77 | 32 | 148212 | 5147 | 64345341 |
Small intestine adenocarcinoma | 11.52 | 9.77 | 6 | 148238 | 143 | 64350345 |
Total bile acids increased | 11.52 | 9.77 | 5 | 148239 | 78 | 64350410 |
Product dispensing error | 11.45 | 9.77 | 6 | 148238 | 11444 | 64339044 |
Diarrhoea | 11.44 | 9.77 | 1471 | 146773 | 721233 | 63629255 |
Ophthalmic herpes simplex | 11.43 | 9.77 | 10 | 148234 | 574 | 64349914 |
Cerebral fungal infection | 11.41 | 9.77 | 8 | 148236 | 331 | 64350157 |
Cleft lip and palate | 11.41 | 9.77 | 5 | 148239 | 80 | 64350408 |
Joint dislocation reduction | 11.38 | 9.77 | 4 | 148240 | 34 | 64350454 |
Lacrimal haemorrhage | 11.38 | 9.77 | 4 | 148240 | 34 | 64350454 |
Overgrowth bacterial | 11.37 | 9.77 | 6 | 148238 | 147 | 64350341 |
Molluscum contagiosum | 11.37 | 9.77 | 9 | 148235 | 449 | 64350039 |
Pulmonary thrombosis | 11.30 | 9.77 | 5 | 148239 | 10513 | 64339975 |
Fasting | 11.28 | 9.77 | 4 | 148240 | 35 | 64350453 |
Tumour lysis syndrome | 11.26 | 9.77 | 17 | 148227 | 19423 | 64331065 |
Presyncope | 11.25 | 9.77 | 42 | 148202 | 35047 | 64315441 |
Germ cell cancer | 11.23 | 9.77 | 6 | 148238 | 151 | 64350337 |
Psychomotor hyperactivity | 11.21 | 9.77 | 10 | 148234 | 14441 | 64336047 |
Stoma complication | 11.16 | 9.77 | 9 | 148235 | 461 | 64350027 |
Gastric fistula | 11.16 | 9.77 | 6 | 148238 | 153 | 64350335 |
Alanine aminotransferase increased | 11.15 | 9.77 | 239 | 148005 | 138792 | 64211696 |
Renal failure | 11.15 | 9.77 | 325 | 147919 | 181363 | 64169125 |
Parvovirus B19 infection | 11.14 | 9.77 | 14 | 148230 | 1225 | 64349263 |
COVID-19 | 11.13 | 9.77 | 211 | 148033 | 64929 | 64285559 |
Idiopathic pulmonary fibrosis | 11.10 | 9.77 | 26 | 148218 | 3774 | 64346714 |
Tonsillitis | 11.10 | 9.77 | 34 | 148210 | 5786 | 64344702 |
Hepatobiliary cancer | 11.10 | 9.77 | 3 | 148241 | 9 | 64350479 |
Neuropsychiatric lupus | 11.09 | 9.77 | 6 | 148238 | 155 | 64350333 |
Klebsiella infection | 11.08 | 9.77 | 60 | 148184 | 13221 | 64337267 |
Rheumatoid factor positive | 11.07 | 9.77 | 126 | 148118 | 34812 | 64315676 |
Iron deficiency | 11.06 | 9.77 | 39 | 148205 | 7138 | 64343350 |
Complication associated with device | 11.04 | 9.77 | 11 | 148233 | 15069 | 64335419 |
Pharyngitis bacterial | 11.02 | 9.77 | 7 | 148237 | 245 | 64350243 |
Peritoneal abscess | 11.02 | 9.77 | 7 | 148237 | 245 | 64350243 |
Toxoplasmosis | 11.02 | 9.77 | 20 | 148224 | 2424 | 64348064 |
Abnormal dreams | 11.00 | 9.77 | 5 | 148239 | 10351 | 64340137 |
Gastrointestinal disorder | 10.98 | 9.77 | 277 | 147967 | 89432 | 64261056 |
Relapsing fever | 10.98 | 9.77 | 8 | 148236 | 352 | 64350136 |
Renal transplant | 10.91 | 9.77 | 19 | 148225 | 2229 | 64348259 |
Panniculitis lobular | 10.90 | 9.77 | 4 | 148240 | 39 | 64350449 |
Oropharyngeal squamous cell carcinoma | 10.90 | 9.77 | 7 | 148237 | 250 | 64350238 |
Cholestasis | 10.89 | 9.77 | 154 | 148090 | 44718 | 64305770 |
Coordination abnormal | 10.86 | 9.77 | 11 | 148233 | 14953 | 64335535 |
Amniotic cavity infection | 10.82 | 9.77 | 11 | 148233 | 763 | 64349725 |
Cryptococcal cutaneous infection | 10.81 | 9.77 | 6 | 148238 | 163 | 64350325 |
Cardiomegaly | 10.78 | 9.77 | 24 | 148220 | 23660 | 64326828 |
Haematuria | 10.78 | 9.77 | 88 | 148156 | 60383 | 64290105 |
Pneumonia herpes viral | 10.75 | 9.77 | 6 | 148238 | 165 | 64350323 |
Generalised tonic-clonic seizure | 10.74 | 9.77 | 51 | 148193 | 39806 | 64310682 |
Injection site reaction | 10.74 | 9.77 | 63 | 148181 | 46601 | 64303887 |
Gastroenteritis clostridial | 10.73 | 9.77 | 11 | 148233 | 771 | 64349717 |
Vascular shunt | 10.72 | 9.77 | 4 | 148240 | 41 | 64350447 |
Superinfection viral | 10.72 | 9.77 | 4 | 148240 | 41 | 64350447 |
Burkholderia pseudomallei infection | 10.72 | 9.77 | 4 | 148240 | 41 | 64350447 |
Renal atrophy | 10.72 | 9.77 | 16 | 148228 | 1648 | 64348840 |
Erectile dysfunction | 10.72 | 9.77 | 8 | 148236 | 12619 | 64337869 |
Mania | 10.69 | 9.77 | 13 | 148231 | 16273 | 64334215 |
Spondyloarthropathy | 10.68 | 9.77 | 11 | 148233 | 775 | 64349713 |
Colonic abscess | 10.67 | 9.77 | 13 | 148231 | 1102 | 64349386 |
Fibroadenoma of breast | 10.65 | 9.77 | 7 | 148237 | 260 | 64350228 |
Cushing's syndrome | 10.62 | 9.77 | 12 | 148232 | 939 | 64349549 |
Tuberculosis gastrointestinal | 10.61 | 9.77 | 9 | 148235 | 495 | 64349993 |
Lupus endocarditis | 10.55 | 9.77 | 6 | 148238 | 171 | 64350317 |
Otorrhoea | 10.53 | 9.77 | 15 | 148229 | 1482 | 64349006 |
Upper respiratory tract irritation | 10.49 | 9.77 | 5 | 148239 | 98 | 64350390 |
Enterobacter infection | 10.48 | 9.77 | 25 | 148219 | 3671 | 64346817 |
Infected fistula | 10.47 | 9.77 | 7 | 148237 | 268 | 64350220 |
Device leakage | 10.46 | 9.77 | 3 | 148241 | 8263 | 64342225 |
Telangiectasia | 10.46 | 9.77 | 13 | 148231 | 1125 | 64349363 |
Dystonia | 10.44 | 9.77 | 17 | 148227 | 18848 | 64331640 |
Paraproteinaemia | 10.44 | 9.77 | 8 | 148236 | 380 | 64350108 |
Laryngeal stenosis | 10.44 | 9.77 | 11 | 148233 | 796 | 64349692 |
Diffuse large B-cell lymphoma stage I | 10.43 | 9.77 | 3 | 148241 | 12 | 64350476 |
Hepatic angiosarcoma | 10.43 | 9.77 | 3 | 148241 | 12 | 64350476 |
Uveal melanoma | 10.43 | 9.77 | 3 | 148241 | 12 | 64350476 |
Myelitis | 10.43 | 9.77 | 18 | 148226 | 2096 | 64348392 |
Dengue fever | 10.43 | 9.77 | 11 | 148233 | 797 | 64349691 |
Lower gastrointestinal haemorrhage | 10.40 | 9.77 | 10 | 148234 | 13929 | 64336559 |
Intestinal polyp | 10.39 | 9.77 | 16 | 148228 | 1695 | 64348793 |
Sudden death | 10.31 | 9.77 | 19 | 148225 | 20077 | 64330411 |
Cutaneous nocardiosis | 10.31 | 9.77 | 6 | 148238 | 179 | 64350309 |
Incorrect route of product administration | 10.29 | 9.77 | 24 | 148220 | 23274 | 64327214 |
Oedema | 10.26 | 9.77 | 149 | 148095 | 91786 | 64258702 |
Central nervous system necrosis | 10.26 | 9.77 | 7 | 148237 | 277 | 64350211 |
Hepatitis chronic active | 10.25 | 9.77 | 6 | 148238 | 181 | 64350307 |
Infusion site paraesthesia | 10.24 | 9.77 | 3 | 148241 | 13 | 64350475 |
Meningeal neoplasm | 10.24 | 9.77 | 3 | 148241 | 13 | 64350475 |
Spleen palpable | 10.24 | 9.77 | 3 | 148241 | 13 | 64350475 |
Superficial spreading melanoma stage unspecified | 10.24 | 9.77 | 7 | 148237 | 278 | 64350210 |
Feeling jittery | 10.23 | 9.77 | 50 | 148194 | 10585 | 64339903 |
Mood altered | 10.23 | 9.77 | 13 | 148231 | 15966 | 64334522 |
Gastric ulcer haemorrhage | 10.22 | 9.77 | 3 | 148241 | 8140 | 64342348 |
Post transplant distal limb syndrome | 10.22 | 9.77 | 9 | 148235 | 521 | 64349967 |
Tinnitus | 10.21 | 9.77 | 42 | 148202 | 34091 | 64316397 |
Peritonitis | 10.20 | 9.77 | 95 | 148149 | 24928 | 64325560 |
Infective aortitis | 10.16 | 9.77 | 4 | 148240 | 48 | 64350440 |
Akathisia | 10.15 | 9.77 | 7 | 148237 | 11503 | 64338985 |
Testicular abscess | 10.09 | 9.77 | 4 | 148240 | 49 | 64350439 |
Tuberculosis of eye | 10.09 | 9.77 | 4 | 148240 | 49 | 64350439 |
Hypoaesthesia | 10.07 | 9.77 | 243 | 148001 | 138865 | 64211623 |
Burkholderia cepacia complex infection | 10.06 | 9.77 | 7 | 148237 | 286 | 64350202 |
Pulmonary venous thrombosis | 10.05 | 9.77 | 5 | 148239 | 108 | 64350380 |
Blood pressure abnormal | 10.04 | 9.77 | 11 | 148233 | 14424 | 64336064 |
Aspiration bone marrow | 10.02 | 9.77 | 4 | 148240 | 50 | 64350438 |
Vertigo | 10.01 | 9.77 | 87 | 148157 | 58924 | 64291564 |
Renal phospholipidosis | 10.01 | 9.77 | 5 | 148239 | 109 | 64350379 |
Blood glucose abnormal | 9.95 | 9.77 | 4 | 148240 | 8909 | 64341579 |
Photophobia | 9.94 | 9.77 | 71 | 148173 | 17222 | 64333266 |
Burning sensation | 9.92 | 9.77 | 70 | 148174 | 49594 | 64300894 |
Bursitis infective | 9.91 | 9.77 | 13 | 148231 | 1187 | 64349301 |
Liver sarcoidosis | 9.89 | 9.77 | 3 | 148241 | 15 | 64350473 |
Conjunctivochalasis | 9.89 | 9.77 | 3 | 148241 | 15 | 64350473 |
Metastases to nasal sinuses | 9.89 | 9.77 | 3 | 148241 | 15 | 64350473 |
Therapeutic response unexpected | 9.89 | 9.77 | 70 | 148174 | 16931 | 64333557 |
Muir-Torre syndrome | 9.88 | 9.77 | 4 | 148240 | 52 | 64350436 |
Rotator cuff syndrome | 9.86 | 9.77 | 8 | 148236 | 12099 | 64338389 |
Pseudolymphoma | 9.86 | 9.77 | 12 | 148232 | 1017 | 64349471 |
Conjunctivitis allergic | 9.85 | 9.77 | 12 | 148232 | 1018 | 64349470 |
Viral sepsis | 9.84 | 9.77 | 5 | 148239 | 113 | 64350375 |
Hepatitis E | 9.84 | 9.77 | 19 | 148225 | 2412 | 64348076 |
Gastrointestinal stoma output decreased | 9.81 | 9.77 | 4 | 148240 | 53 | 64350435 |
Koebner phenomenon | 9.81 | 9.77 | 4 | 148240 | 53 | 64350435 |
Isosporiasis | 9.80 | 9.77 | 5 | 148239 | 114 | 64350374 |
Allergy to chemicals | 9.78 | 9.77 | 12 | 148232 | 1025 | 64349463 |
Acute pulmonary oedema | 9.78 | 9.77 | 9 | 148235 | 12800 | 64337688 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Hydrops foetalis | 56.23 | 32.05 | 17 | 194 | 80 | 84387 |
Source | Code | Description |
---|---|---|
ATC | L04AX01 | ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS IMMUNOSUPPRESSANTS IMMUNOSUPPRESSANTS Other immunosuppressants |
FDA CS | M0015066 | Nucleosides |
FDA CS | M0018169 | Purines |
FDA MoA | N0000000233 | Nucleic Acid Synthesis Inhibitors |
MeSH PA | D000963 | Antimetabolites |
MeSH PA | D000964 | Antimetabolites, Antineoplastic |
MeSH PA | D000970 | Antineoplastic Agents |
MeSH PA | D018501 | Antirheumatic Agents |
MeSH PA | D007155 | Immunologic Factors |
MeSH PA | D007166 | Immunosuppressive Agents |
MeSH PA | D009676 | Noxae |
FDA EPC | N0000175712 | Purine Antimetabolite |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Refractory idiopathic thrombocytopenic purpura | indication | 13172003 | |
Relapsing multiple sclerosis | indication | 24700007 | DOID:2377 |
Crohn's disease | indication | 34000006 | |
Pemphigus vulgaris | indication | 49420001 | DOID:0060851 |
Systemic lupus erythematosus | indication | 55464009 | DOID:9074 |
Ulcerative colitis | indication | 64766004 | DOID:8577 |
Rheumatoid arthritis | indication | 69896004 | DOID:7148 |
Bullous pemphigoid | indication | 77090002 | DOID:8506 |
Myasthenia gravis | indication | 91637004 | DOID:437 |
Polyarteritis nodosa | indication | 155441006 | DOID:9810 |
Behcet's disease | indication | 310701003 | DOID:13241 |
Dermatomyositis | indication | 396230008 | DOID:10223 |
Autoimmune hepatitis | indication | 408335007 | |
Refractory autoimmune haemolytic anaemia | indication | 413603009 | DOID:718 |
Prevention of Kidney Transplant Rejection | indication | ||
Polymyositis | off-label use | 31384009 | |
Prevention of Lung Transplant Rejection | off-label use | ||
Prevention of Cardiac Transplant Rejection | off-label use | ||
Prevention of Liver Transplant Rejection | off-label use | ||
Mycosis | contraindication | 3218000 | DOID:1564 |
Viral disease | contraindication | 34014006 | DOID:934 |
Hepatic vein thrombosis | contraindication | 38739001 | DOID:11512 |
Bacterial infectious disease | contraindication | 87628006 | |
Malignant lymphoma | contraindication | 118600007 | DOID:0060058 |
Liver function tests abnormal | contraindication | 166603001 | |
Acute pancreatitis | contraindication | 197456007 | DOID:2913 |
Impaired renal function disorder | contraindication | 197663003 | |
Anemia | contraindication | 271737000 | DOID:2355 |
Pregnancy, function | contraindication | 289908002 | |
Thrombocytopenic disorder | contraindication | 302215000 | DOID:1588 |
Bone marrow depression | contraindication | 307762000 | |
Hepatosplenic T-cell lymphoma | contraindication | 445406001 | |
Thiopurine S-Methyltransferase Deficiency | contraindication | ||
Severe Leukopenia | contraindication | ||
Protozoal Infection | contraindication |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 8.28 | acidic |
pKa2 | 3.24 | Basic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
ATP-binding cassette sub-family G member 2 | Transporter | WOMBAT-PK | |||||||
Multidrug resistance-associated protein 5 | Transporter | WOMBAT-PK | |||||||
Multidrug resistance-associated protein 4 | Transporter | WOMBAT-PK | |||||||
Ras-related C3 botulinum toxin substrate 1 | Enzyme | WOMBAT-PK | |||||||
Thiopurine S-methyltransferase | Enzyme | WOMBAT-PK |
ID | Source |
---|---|
4018766 | VUID |
N0000147069 | NUI |
D00238 | KEGG_DRUG |
55774-33-9 | SECONDARY_CAS_RN |
1256 | RXNORM |
C0004482 | UMLSCUI |
CHEMBL1542 | ChEMBL_ID |
DB00993 | DRUGBANK_ID |
CHEMBL1200400 | ChEMBL_ID |
D001379 | MESH_DESCRIPTOR_UI |
2265 | PUBCHEM_CID |
7120 | IUPHAR_LIGAND_ID |
1291 | INN_ID |
MRK240IY2L | UNII |
3341 | MMSL |
4234 | MMSL |
4235 | MMSL |
6041 | MMSL |
d00024 | MMSL |
003419 | NDDF |
004123 | NDDF |
4018766 | VANDF |
111165009 | SNOMEDCT_US |
372574004 | SNOMEDCT_US |
67221004 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Azathioprine Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9566 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 100 mg | INTRAVENOUS | ANDA | 22 sections |
Azathioprine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-1005 | TABLET | 50 mg | ORAL | ANDA | 23 sections |
Azathioprine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 21695-484 | TABLET | 50 mg | ORAL | ANDA | 20 sections |
Azathioprine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 33261-758 | TABLET | 50 mg | ORAL | ANDA | 20 sections |
AZATHIOPRINE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42291-071 | TABLET | 50 mg | ORAL | ANDA | 19 sections |
Azathioprine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 43353-745 | TABLET | 50 mg | ORAL | ANDA | 23 sections |
Azathioprine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51407-182 | TABLET | 50 mg | ORAL | ANDA | 14 sections |
IMURAN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 54766-590 | TABLET | 50 mg | ORAL | NDA | 23 sections |
Azathioprine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 54868-5310 | TABLET | 50 mg | ORAL | ANDA | 20 sections |
AZATHIOPRINE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 60219-1076 | TABLET | 50 mg | ORAL | ANDA | 19 sections |
AZATHIOPRINE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 60219-2036 | TABLET | 75 mg | ORAL | ANDA | 19 sections |
AZATHIOPRINE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 60219-2037 | TABLET | 100 mg | ORAL | ANDA | 19 sections |
IMURAN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 65483-590 | TABLET | 50 mg | ORAL | NDA | 23 sections |
Azasan | HUMAN PRESCRIPTION DRUG LABEL | 1 | 65649-231 | TABLET | 75 mg | ORAL | ANDA | 13 sections |
Azasan | HUMAN PRESCRIPTION DRUG LABEL | 1 | 65649-241 | TABLET | 100 mg | ORAL | ANDA | 13 sections |
Azathioprine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 65841-602 | TABLET | 50 mg | ORAL | ANDA | 1 sections |
Azathioprine | Human Prescription Drug Label | 1 | 67877-492 | TABLET | 25 mg | ORAL | ANDA | 21 sections |
Azathioprine | Human Prescription Drug Label | 1 | 67877-492 | TABLET | 25 mg | ORAL | ANDA | 21 sections |
Azathioprine | Human Prescription Drug Label | 1 | 67877-493 | TABLET | 50 mg | ORAL | ANDA | 21 sections |
Azathioprine | Human Prescription Drug Label | 1 | 67877-493 | TABLET | 50 mg | ORAL | ANDA | 21 sections |
Azathioprine | Human Prescription Drug Label | 1 | 67877-494 | TABLET | 75 mg | ORAL | ANDA | 21 sections |
Azathioprine | Human Prescription Drug Label | 1 | 67877-494 | TABLET | 75 mg | ORAL | ANDA | 21 sections |
Azathioprine | Human Prescription Drug Label | 1 | 67877-495 | TABLET | 100 mg | ORAL | ANDA | 21 sections |
Azathioprine | Human Prescription Drug Label | 1 | 67877-495 | TABLET | 100 mg | ORAL | ANDA | 21 sections |
Azathioprine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 68084-229 | TABLET | 50 mg | ORAL | ANDA | 20 sections |
Azathioprine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 68382-003 | TABLET | 50 1 | ORAL | ANDA | 20 sections |
Azathioprine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 68382-118 | TABLET | 25 1 | ORAL | ANDA | 20 sections |
Azathioprine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 68382-119 | TABLET | 75 1 | ORAL | ANDA | 20 sections |
Azathioprine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 68382-120 | TABLET | 100 1 | ORAL | ANDA | 20 sections |
Azathioprine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 68462-502 | TABLET | 50 mg | ORAL | ANDA | 14 sections |