Stem definition | Drug id | CAS RN |
---|---|---|
folic acid analogues | 1751 | 59-05-2 |
Dose | Unit | Route |
---|---|---|
2.50 | mg | O |
2.50 | mg | P |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 3 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 0.45 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 81 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 1.10 µM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 33 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Vd (Volume of distribution) | 0.43 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 2.10 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.37 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 3.90 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
Dec. 7, 1953 | FDA | DAVA PHARMS INC |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug ineffective | 14992.61 | 11.08 | 30841 | 633702 | 646997 | 45374522 |
Rheumatoid arthritis | 8649.62 | 11.08 | 13582 | 650961 | 226633 | 45794886 |
Drug intolerance | 5187.12 | 11.08 | 8250 | 656293 | 138799 | 45882720 |
Treatment failure | 3917.93 | 11.08 | 5674 | 658869 | 87413 | 45934106 |
Joint swelling | 2822.39 | 11.08 | 6855 | 657688 | 159218 | 45862301 |
Therapeutic product effect incomplete | 2770.78 | 11.08 | 4400 | 660143 | 73753 | 45947766 |
Contraindicated product administered | 2259.93 | 11.08 | 4069 | 660474 | 75878 | 45945641 |
Arthralgia | 2219.04 | 11.08 | 10651 | 653892 | 353952 | 45667567 |
Therapeutic product effect decreased | 2184.62 | 11.08 | 4085 | 660458 | 78516 | 45943003 |
Synovitis | 2098.73 | 11.08 | 3391 | 661152 | 57684 | 45963835 |
Death | 2078.70 | 11.08 | 1095 | 663448 | 334453 | 45687066 |
Completed suicide | 1923.10 | 11.08 | 30 | 664513 | 145890 | 45875629 |
Drug hypersensitivity | 1879.34 | 11.08 | 7649 | 656894 | 236176 | 45785343 |
Liver function test increased | 1386.83 | 11.08 | 1668 | 662875 | 21158 | 46000361 |
Musculoskeletal stiffness | 1319.15 | 11.08 | 3711 | 660832 | 94282 | 45927237 |
Arthropathy | 1004.87 | 11.08 | 3067 | 661476 | 81633 | 45939886 |
Dyspnoea | 926.95 | 11.08 | 3988 | 660555 | 511560 | 45509959 |
Alopecia | 926.76 | 11.08 | 4666 | 659877 | 157748 | 45863771 |
Lymphoproliferative disorder | 853.79 | 11.08 | 512 | 664031 | 2180 | 46019339 |
Acute kidney injury | 803.49 | 11.08 | 1325 | 663218 | 234530 | 45786989 |
Constipation | 776.88 | 11.08 | 799 | 663744 | 173298 | 45848221 |
Psoriatic arthropathy | 775.16 | 11.08 | 1645 | 662898 | 34734 | 45986785 |
Hypotension | 763.46 | 11.08 | 1338 | 663205 | 231251 | 45790268 |
Hepatic enzyme increased | 749.14 | 11.08 | 2714 | 661829 | 79073 | 45942446 |
Dehydration | 708.58 | 11.08 | 735 | 663808 | 158805 | 45862714 |
C-reactive protein abnormal | 706.84 | 11.08 | 1164 | 663379 | 20106 | 46001413 |
Confusional state | 701.85 | 11.08 | 744 | 663799 | 159148 | 45862371 |
Drug abuse | 685.91 | 11.08 | 58 | 664485 | 63350 | 45958169 |
Intentional overdose | 671.76 | 11.08 | 71 | 664472 | 64873 | 45956646 |
Hyponatraemia | 661.37 | 11.08 | 307 | 664236 | 101025 | 45920494 |
Infection | 658.91 | 11.08 | 3688 | 660855 | 129904 | 45891615 |
Injection site pain | 648.01 | 11.08 | 3131 | 661412 | 104021 | 45917498 |
Somnolence | 625.66 | 11.08 | 785 | 663758 | 155736 | 45865783 |
Arthritis | 599.04 | 11.08 | 2433 | 662110 | 74883 | 45946636 |
Bradycardia | 576.74 | 11.08 | 120 | 664423 | 66178 | 45955341 |
Dizziness | 571.23 | 11.08 | 2698 | 661845 | 337716 | 45683803 |
Cardiac arrest | 569.90 | 11.08 | 287 | 664256 | 90112 | 45931407 |
Pain | 567.14 | 11.08 | 9729 | 654814 | 467219 | 45554300 |
Red blood cell sedimentation rate increased | 564.69 | 11.08 | 1100 | 663443 | 21789 | 45999730 |
Psoriasis | 563.19 | 11.08 | 2415 | 662128 | 76189 | 45945330 |
Abdominal discomfort | 547.36 | 11.08 | 3856 | 660687 | 147309 | 45874210 |
Anaemia | 542.80 | 11.08 | 1847 | 662696 | 253932 | 45767587 |
Overdose | 539.44 | 11.08 | 398 | 664145 | 101581 | 45919938 |
Mouth ulceration | 527.84 | 11.08 | 1175 | 663368 | 25657 | 45995862 |
Anxiety | 521.87 | 11.08 | 1133 | 663410 | 180824 | 45840695 |
Red blood cell sedimentation rate abnormal | 515.50 | 11.08 | 792 | 663751 | 12857 | 46008662 |
Cardio-respiratory arrest | 509.28 | 11.08 | 114 | 664429 | 59755 | 45961764 |
Electrocardiogram QT prolonged | 508.65 | 11.08 | 65 | 664478 | 51260 | 45970259 |
Loss of personal independence in daily activities | 503.57 | 11.08 | 1874 | 662669 | 55309 | 45966210 |
Tremor | 482.06 | 11.08 | 561 | 663982 | 115078 | 45906441 |
Multiple sclerosis relapse | 480.01 | 11.08 | 30 | 664513 | 42095 | 45979424 |
Hyperkalaemia | 477.30 | 11.08 | 75 | 664468 | 50634 | 45970885 |
Injection site reaction | 465.45 | 11.08 | 1620 | 662923 | 46229 | 45975290 |
Exposure during pregnancy | 457.52 | 11.08 | 519 | 664024 | 107693 | 45913826 |
Joint stiffness | 451.24 | 11.08 | 1112 | 663431 | 25996 | 45995523 |
Asthenia | 451.00 | 11.08 | 2591 | 661952 | 308484 | 45713035 |
C-reactive protein increased | 436.57 | 11.08 | 1822 | 662721 | 56768 | 45964751 |
Condition aggravated | 435.15 | 11.08 | 5364 | 659179 | 239688 | 45781831 |
Decreased appetite | 429.33 | 11.08 | 1373 | 663170 | 192463 | 45829056 |
Mobility decreased | 421.15 | 11.08 | 1845 | 662698 | 58749 | 45962770 |
Toxicity to various agents | 418.53 | 11.08 | 1575 | 662968 | 210191 | 45811328 |
Hand deformity | 411.49 | 11.08 | 1254 | 663289 | 33320 | 45988199 |
Inflammation | 409.90 | 11.08 | 1575 | 662968 | 47206 | 45974313 |
Hallucination | 407.38 | 11.08 | 104 | 664439 | 49847 | 45971672 |
Diarrhoea | 404.47 | 11.08 | 5578 | 658965 | 554024 | 45467495 |
Cardiac failure congestive | 404.46 | 11.08 | 425 | 664118 | 91325 | 45930194 |
Swelling | 398.52 | 11.08 | 3085 | 661458 | 121426 | 45900093 |
International normalised ratio increased | 397.28 | 11.08 | 90 | 664453 | 46793 | 45974726 |
Rheumatoid factor positive | 396.81 | 11.08 | 891 | 663652 | 19570 | 46001949 |
Agitation | 386.81 | 11.08 | 152 | 664391 | 55263 | 45966256 |
Pancytopenia | 384.28 | 11.08 | 2295 | 662248 | 82763 | 45938756 |
Drug interaction | 381.78 | 11.08 | 1541 | 663002 | 201553 | 45819966 |
Systemic lupus erythematosus | 381.14 | 11.08 | 1887 | 662656 | 63293 | 45958226 |
Rheumatoid nodule | 380.13 | 11.08 | 551 | 663992 | 8469 | 46013050 |
Gastrointestinal disorder | 378.87 | 11.08 | 1767 | 662776 | 57809 | 45963710 |
Oedema peripheral | 377.28 | 11.08 | 1098 | 663445 | 158608 | 45862911 |
Hypokalaemia | 375.51 | 11.08 | 419 | 664124 | 87605 | 45933914 |
Suicide attempt | 374.33 | 11.08 | 157 | 664386 | 54879 | 45966640 |
Seizure | 373.03 | 11.08 | 742 | 663801 | 122312 | 45899207 |
Peripheral swelling | 370.73 | 11.08 | 3657 | 660886 | 154414 | 45867105 |
Foot deformity | 361.99 | 11.08 | 726 | 663817 | 14699 | 46006820 |
Device expulsion | 361.08 | 11.08 | 6 | 664537 | 27536 | 45993983 |
Rhabdomyolysis | 348.07 | 11.08 | 84 | 664459 | 41825 | 45979694 |
Hypoglycaemia | 346.30 | 11.08 | 170 | 664373 | 54179 | 45967340 |
Syncope | 339.57 | 11.08 | 607 | 663936 | 104196 | 45917323 |
Bone erosion | 331.67 | 11.08 | 530 | 664013 | 8913 | 46012606 |
Therapeutic response decreased | 330.23 | 11.08 | 1353 | 663190 | 41792 | 45979727 |
Plasma cell myeloma | 317.08 | 11.08 | 118 | 664425 | 44360 | 45977159 |
Pneumocystis jirovecii pneumonia | 316.05 | 11.08 | 682 | 663861 | 14566 | 46006953 |
Lactic acidosis | 312.73 | 11.08 | 53 | 664490 | 33856 | 45987663 |
Haemoglobin decreased | 310.73 | 11.08 | 878 | 663665 | 128071 | 45893448 |
Depressed level of consciousness | 310.41 | 11.08 | 144 | 664399 | 47425 | 45974094 |
Osteoarthritis | 309.12 | 11.08 | 1718 | 662825 | 60307 | 45961212 |
Fall | 305.70 | 11.08 | 3102 | 661441 | 325995 | 45695524 |
Tuberculosis | 305.59 | 11.08 | 535 | 664008 | 9730 | 46011789 |
Herpes zoster | 299.93 | 11.08 | 1821 | 662722 | 66051 | 45955468 |
Musculoskeletal pain | 296.36 | 11.08 | 1860 | 662683 | 68268 | 45953251 |
Joint range of motion decreased | 294.83 | 11.08 | 660 | 663883 | 14464 | 46007055 |
Respiratory arrest | 294.47 | 11.08 | 61 | 664482 | 33755 | 45987764 |
Drug withdrawal syndrome | 293.50 | 11.08 | 26 | 664517 | 27358 | 45994161 |
Product use issue | 292.21 | 11.08 | 2326 | 662217 | 92318 | 45929201 |
Fluid retention | 290.11 | 11.08 | 184 | 664359 | 50862 | 45970657 |
Knee arthroplasty | 289.72 | 11.08 | 867 | 663676 | 22798 | 45998721 |
Injection site erythema | 288.21 | 11.08 | 1931 | 662612 | 72496 | 45949023 |
Malignant neoplasm progression | 286.93 | 11.08 | 300 | 664243 | 64626 | 45956893 |
Nodule | 283.19 | 11.08 | 662 | 663881 | 14943 | 46006576 |
Coma | 277.07 | 11.08 | 253 | 664290 | 58096 | 45963423 |
Pain in extremity | 275.28 | 11.08 | 5190 | 659353 | 253490 | 45768029 |
Muscle spasms | 275.19 | 11.08 | 868 | 663675 | 122245 | 45899274 |
Tachycardia | 274.96 | 11.08 | 633 | 663910 | 98989 | 45922530 |
Metabolic acidosis | 274.56 | 11.08 | 104 | 664439 | 38676 | 45982843 |
Diffuse large B-cell lymphoma | 272.78 | 11.08 | 378 | 664165 | 5560 | 46015959 |
Acute graft versus host disease | 270.43 | 11.08 | 310 | 664233 | 3720 | 46017799 |
Interstitial lung disease | 269.94 | 11.08 | 1496 | 663047 | 52453 | 45969066 |
Pulmonary fibrosis | 266.99 | 11.08 | 758 | 663785 | 19334 | 46002185 |
Pemphigus | 262.67 | 11.08 | 1308 | 663235 | 43966 | 45977553 |
Intentional self-injury | 261.57 | 11.08 | 22 | 664521 | 24144 | 45997375 |
Gastrointestinal haemorrhage | 260.74 | 11.08 | 437 | 664106 | 76936 | 45944583 |
Hospitalisation | 260.26 | 11.08 | 311 | 664232 | 63074 | 45958445 |
Product quality issue | 256.76 | 11.08 | 93 | 664450 | 35555 | 45985964 |
Balance disorder | 255.02 | 11.08 | 326 | 664217 | 64195 | 45957324 |
Injection site bruising | 254.35 | 11.08 | 1094 | 663449 | 34542 | 45986977 |
Blood glucose increased | 253.68 | 11.08 | 395 | 664148 | 71618 | 45949901 |
Nasopharyngitis | 251.65 | 11.08 | 3321 | 661222 | 150677 | 45870842 |
Foetal exposure during pregnancy | 248.81 | 11.08 | 65 | 664478 | 30682 | 45990837 |
Basal cell carcinoma | 248.36 | 11.08 | 748 | 663795 | 19739 | 46001780 |
Unresponsive to stimuli | 247.39 | 11.08 | 75 | 664468 | 32099 | 45989420 |
Finger deformity | 246.78 | 11.08 | 335 | 664208 | 4827 | 46016692 |
Chest pain | 244.73 | 11.08 | 1488 | 663055 | 174836 | 45846683 |
Sopor | 242.28 | 11.08 | 9 | 664534 | 19819 | 46001700 |
Vomiting | 241.31 | 11.08 | 4771 | 659772 | 448023 | 45573496 |
Cerebrovascular accident | 241.12 | 11.08 | 691 | 663852 | 100348 | 45921171 |
Platelet count decreased | 240.95 | 11.08 | 681 | 663862 | 99343 | 45922176 |
Renal failure | 239.29 | 11.08 | 822 | 663721 | 112772 | 45908747 |
Grip strength decreased | 237.55 | 11.08 | 434 | 664109 | 8172 | 46013347 |
Lower respiratory tract infection | 235.14 | 11.08 | 1465 | 663078 | 53624 | 45967895 |
Product dose omission issue | 234.46 | 11.08 | 1421 | 663122 | 167099 | 45854420 |
Serotonin syndrome | 234.40 | 11.08 | 33 | 664510 | 24187 | 45997332 |
Sedation | 229.43 | 11.08 | 28 | 664515 | 22882 | 45998637 |
Drug reaction with eosinophilia and systemic symptoms | 226.97 | 11.08 | 69 | 664474 | 29479 | 45992040 |
Juvenile idiopathic arthritis | 226.77 | 11.08 | 287 | 664256 | 3845 | 46017674 |
Depression | 224.45 | 11.08 | 1458 | 663085 | 168646 | 45852873 |
Fear of injection | 224.36 | 11.08 | 286 | 664257 | 3861 | 46017658 |
Injection site pruritus | 221.96 | 11.08 | 1136 | 663407 | 38607 | 45982912 |
Loss of consciousness | 220.77 | 11.08 | 794 | 663749 | 107444 | 45914075 |
Pulmonary embolism | 217.87 | 11.08 | 802 | 663741 | 107783 | 45913736 |
Musculoskeletal disorder | 215.92 | 11.08 | 596 | 663947 | 14949 | 46006570 |
Hypoxia | 208.94 | 11.08 | 258 | 664285 | 51580 | 45969939 |
Mucosal inflammation | 208.62 | 11.08 | 1101 | 663442 | 37875 | 45983644 |
Pulmonary tuberculosis | 208.15 | 11.08 | 295 | 664248 | 4436 | 46017083 |
Hyperhidrosis | 207.10 | 11.08 | 619 | 663924 | 88689 | 45932830 |
Chest discomfort | 206.22 | 11.08 | 630 | 663913 | 89639 | 45931880 |
Suicidal ideation | 203.63 | 11.08 | 304 | 664239 | 56078 | 45965441 |
Lymphoma | 202.32 | 11.08 | 438 | 664105 | 9375 | 46012144 |
Epstein-Barr virus infection | 201.19 | 11.08 | 353 | 664190 | 6431 | 46015088 |
Pulmonary arterial hypertension | 200.14 | 11.08 | 60 | 664483 | 25868 | 45995651 |
Insomnia | 193.32 | 11.08 | 1463 | 663080 | 163461 | 45858058 |
Fluid overload | 190.62 | 11.08 | 74 | 664469 | 27111 | 45994408 |
Blood potassium decreased | 190.44 | 11.08 | 157 | 664386 | 37906 | 45983613 |
Leukoencephalopathy | 190.12 | 11.08 | 259 | 664284 | 3745 | 46017774 |
Atrial fibrillation | 190.01 | 11.08 | 793 | 663750 | 102797 | 45918722 |
Injection site swelling | 189.01 | 11.08 | 1099 | 663444 | 39228 | 45982291 |
Chronic graft versus host disease | 188.59 | 11.08 | 213 | 664330 | 2512 | 46019007 |
Cardiac failure | 188.35 | 11.08 | 550 | 663993 | 79398 | 45942121 |
Asthma | 187.67 | 11.08 | 670 | 663873 | 90872 | 45930647 |
Dysgeusia | 184.68 | 11.08 | 182 | 664361 | 40309 | 45981210 |
Vision blurred | 183.70 | 11.08 | 554 | 663989 | 79154 | 45942365 |
Blood pressure decreased | 183.31 | 11.08 | 333 | 664210 | 56826 | 45964693 |
Mental status changes | 182.17 | 11.08 | 164 | 664379 | 37924 | 45983595 |
Uveitis | 179.65 | 11.08 | 387 | 664156 | 8254 | 46013265 |
Skin ulcer | 179.31 | 11.08 | 925 | 663618 | 31533 | 45989986 |
Abdominal pain | 177.59 | 11.08 | 2259 | 662284 | 227772 | 45793747 |
Neuropathy peripheral | 177.32 | 11.08 | 679 | 663864 | 90214 | 45931305 |
Tuberculin test positive | 176.63 | 11.08 | 216 | 664327 | 2788 | 46018731 |
Palpitations | 176.08 | 11.08 | 727 | 663816 | 94532 | 45926987 |
Myalgia | 175.82 | 11.08 | 1029 | 663514 | 122059 | 45899460 |
Disorientation | 175.33 | 11.08 | 160 | 664383 | 36758 | 45984761 |
Ankylosing spondylitis | 173.76 | 11.08 | 330 | 664213 | 6407 | 46015112 |
Restlessness | 173.23 | 11.08 | 73 | 664470 | 25451 | 45996068 |
Orthostatic hypotension | 173.09 | 11.08 | 67 | 664476 | 24591 | 45996928 |
Pulmonary hypertension | 172.12 | 11.08 | 155 | 664388 | 35838 | 45985681 |
Sinusitis | 171.88 | 11.08 | 2698 | 661845 | 127070 | 45894449 |
Joint destruction | 171.62 | 11.08 | 215 | 664328 | 2849 | 46018670 |
Anti-cyclic citrullinated peptide antibody positive | 171.41 | 11.08 | 631 | 663912 | 18514 | 46003005 |
Full blood count decreased | 168.56 | 11.08 | 53 | 664490 | 22158 | 45999361 |
Disease progression | 168.00 | 11.08 | 698 | 663845 | 90602 | 45930917 |
Dyspnoea exertional | 166.66 | 11.08 | 287 | 664256 | 50002 | 45971517 |
Flushing | 166.05 | 11.08 | 426 | 664117 | 64188 | 45957331 |
Blood iron abnormal | 165.81 | 11.08 | 215 | 664328 | 2955 | 46018564 |
Pulmonary oedema | 164.53 | 11.08 | 297 | 664246 | 50808 | 45970711 |
Epstein-Barr virus associated lymphoproliferative disorder | 163.65 | 11.08 | 149 | 664394 | 1330 | 46020189 |
Cognitive disorder | 163.41 | 11.08 | 170 | 664373 | 36713 | 45984806 |
Epstein Barr virus positive mucocutaneous ulcer | 162.59 | 11.08 | 76 | 664467 | 166 | 46021353 |
Lung disorder | 161.28 | 11.08 | 1113 | 663430 | 42191 | 45979328 |
Breast cancer | 158.50 | 11.08 | 1151 | 663392 | 44367 | 45977152 |
Stomatitis | 157.84 | 11.08 | 1576 | 662967 | 66721 | 45954798 |
Aggression | 157.68 | 11.08 | 63 | 664480 | 22681 | 45998838 |
Emotional distress | 156.94 | 11.08 | 124 | 664419 | 30583 | 45990936 |
Lethargy | 155.41 | 11.08 | 308 | 664235 | 50863 | 45970656 |
Dyskinesia | 155.29 | 11.08 | 111 | 664432 | 28814 | 45992705 |
Infusion related reaction | 154.26 | 11.08 | 2156 | 662387 | 99052 | 45922467 |
Withdrawal syndrome | 153.23 | 11.08 | 35 | 664508 | 18099 | 46003420 |
Premature delivery | 153.21 | 11.08 | 61 | 664482 | 22008 | 45999511 |
Caesarean section | 152.98 | 11.08 | 26 | 664517 | 16577 | 46004942 |
Pneumonia aspiration | 150.06 | 11.08 | 137 | 664406 | 31468 | 45990051 |
Joint effusion | 149.21 | 11.08 | 442 | 664101 | 11553 | 46009966 |
Abnormal behaviour | 148.18 | 11.08 | 57 | 664486 | 21001 | 46000518 |
Disability | 147.39 | 11.08 | 396 | 664147 | 9771 | 46011748 |
Hyperglycaemia | 147.24 | 11.08 | 169 | 664374 | 34902 | 45986617 |
Gastrooesophageal reflux disease | 147.18 | 11.08 | 552 | 663991 | 73792 | 45947727 |
Fibromyalgia | 147.10 | 11.08 | 956 | 663587 | 35507 | 45986012 |
Device dislocation | 146.93 | 11.08 | 63 | 664480 | 21739 | 45999780 |
Oedema | 146.90 | 11.08 | 477 | 664066 | 66594 | 45954925 |
Tenosynovitis | 146.52 | 11.08 | 328 | 664215 | 7187 | 46014332 |
White blood cell count decreased | 146.39 | 11.08 | 965 | 663578 | 111266 | 45910253 |
Fine motor skill dysfunction | 145.78 | 11.08 | 219 | 664324 | 3481 | 46018038 |
Premature baby | 143.31 | 11.08 | 40 | 664503 | 18072 | 46003447 |
Arthritis bacterial | 143.06 | 11.08 | 277 | 664266 | 5459 | 46016060 |
Palmar-plantar erythrodysaesthesia syndrome | 142.84 | 11.08 | 56 | 664487 | 20395 | 46001124 |
Blood creatinine increased | 141.87 | 11.08 | 582 | 663961 | 75821 | 45945698 |
Delirium | 141.06 | 11.08 | 194 | 664349 | 37034 | 45984485 |
Blood alkaline phosphatase increased | 139.70 | 11.08 | 217 | 664326 | 39392 | 45982127 |
Hypomagnesaemia | 139.15 | 11.08 | 71 | 664472 | 22139 | 45999380 |
Disseminated tuberculosis | 138.28 | 11.08 | 183 | 664360 | 2569 | 46018950 |
Deep vein thrombosis | 138.13 | 11.08 | 624 | 663919 | 79149 | 45942370 |
Wheezing | 137.15 | 11.08 | 352 | 664191 | 53034 | 45968485 |
Malignant melanoma | 135.86 | 11.08 | 386 | 664157 | 9848 | 46011671 |
Hallucination, visual | 135 | 11.08 | 43 | 664500 | 17830 | 46003689 |
Disturbance in attention | 134.77 | 11.08 | 150 | 664393 | 31410 | 45990109 |
Injury | 133.70 | 11.08 | 265 | 664278 | 43762 | 45977757 |
Dysphagia | 133.11 | 11.08 | 606 | 663937 | 76706 | 45944813 |
Pulmonary toxicity | 132.49 | 11.08 | 239 | 664304 | 4454 | 46017065 |
Pregnancy | 130.79 | 11.08 | 116 | 664427 | 27021 | 45994498 |
Neuroleptic malignant syndrome | 129.50 | 11.08 | 7 | 664536 | 11115 | 46010404 |
Adverse reaction | 129.47 | 11.08 | 327 | 664216 | 7763 | 46013756 |
B-cell lymphoma | 128.40 | 11.08 | 194 | 664349 | 3100 | 46018419 |
Pulmonary mass | 128.00 | 11.08 | 549 | 663994 | 17308 | 46004211 |
Angiocentric lymphoma | 127.85 | 11.08 | 81 | 664462 | 388 | 46021131 |
Deformity | 127.47 | 11.08 | 304 | 664239 | 6953 | 46014566 |
Acute graft versus host disease in skin | 126.87 | 11.08 | 183 | 664360 | 2799 | 46018720 |
Injection site warmth | 126.74 | 11.08 | 458 | 664085 | 13314 | 46008205 |
Psychotic disorder | 126.51 | 11.08 | 83 | 664460 | 22538 | 45998981 |
Blood urea increased | 126.29 | 11.08 | 105 | 664438 | 25247 | 45996272 |
Diabetic ketoacidosis | 125.32 | 11.08 | 51 | 664492 | 18159 | 46003360 |
Epistaxis | 124.99 | 11.08 | 481 | 664062 | 63824 | 45957695 |
Poisoning | 124.43 | 11.08 | 24 | 664519 | 13970 | 46007549 |
Pustular psoriasis | 124.31 | 11.08 | 213 | 664330 | 3804 | 46017715 |
Glossodynia | 124.21 | 11.08 | 1067 | 663476 | 43306 | 45978213 |
Sinus bradycardia | 123.90 | 11.08 | 23 | 664520 | 13759 | 46007760 |
Coronary artery disease | 123.79 | 11.08 | 180 | 664363 | 33572 | 45987947 |
Lupus-like syndrome | 122.36 | 11.08 | 314 | 664229 | 7530 | 46013989 |
Hip arthroplasty | 121.59 | 11.08 | 546 | 663997 | 17566 | 46003953 |
Torsade de pointes | 121.34 | 11.08 | 15 | 664528 | 12139 | 46009380 |
Impaired work ability | 121.22 | 11.08 | 426 | 664117 | 12210 | 46009309 |
Ventricular tachycardia | 120.93 | 11.08 | 45 | 664498 | 16922 | 46004597 |
Heart rate increased | 120.71 | 11.08 | 600 | 663943 | 74191 | 45947328 |
Myocardial infarction | 120.51 | 11.08 | 852 | 663691 | 96676 | 45924843 |
Febrile bone marrow aplasia | 120.04 | 11.08 | 287 | 664256 | 6575 | 46014944 |
Arrhythmia | 119.92 | 11.08 | 194 | 664349 | 34647 | 45986872 |
Product use in unapproved indication | 119.88 | 11.08 | 1878 | 662665 | 88395 | 45933124 |
Neutrophil count decreased | 119.69 | 11.08 | 276 | 664267 | 43150 | 45978369 |
Osteoporosis | 118.71 | 11.08 | 986 | 663557 | 39622 | 45981897 |
Right ventricular failure | 117.56 | 11.08 | 41 | 664502 | 16052 | 46005467 |
Respiratory depression | 116.59 | 11.08 | 14 | 664529 | 11586 | 46009933 |
Rheumatoid lung | 116.15 | 11.08 | 132 | 664411 | 1568 | 46019951 |
Histoplasmosis disseminated | 114.41 | 11.08 | 108 | 664435 | 1014 | 46020505 |
Blood creatine phosphokinase increased | 113.80 | 11.08 | 136 | 664407 | 27588 | 45993931 |
Irritability | 113.57 | 11.08 | 147 | 664396 | 28799 | 45992720 |
Haemophagocytic lymphohistiocytosis | 113.05 | 11.08 | 317 | 664226 | 8025 | 46013494 |
Arthrodesis | 112.91 | 11.08 | 150 | 664393 | 2114 | 46019405 |
Intentional product misuse | 112.59 | 11.08 | 322 | 664221 | 46806 | 45974713 |
Diverticulitis | 110.76 | 11.08 | 828 | 663715 | 32211 | 45989308 |
Dactylitis | 110.64 | 11.08 | 109 | 664434 | 1084 | 46020435 |
Angioedema | 110.08 | 11.08 | 248 | 664295 | 39094 | 45982425 |
Chronic kidney disease | 108.46 | 11.08 | 265 | 664278 | 40606 | 45980913 |
Hypocalcaemia | 108.24 | 11.08 | 133 | 664410 | 26652 | 45994867 |
Panniculitis | 107.91 | 11.08 | 246 | 664297 | 5458 | 46016061 |
Urinary retention | 107.87 | 11.08 | 127 | 664416 | 25934 | 45995585 |
Extrapyramidal disorder | 107.53 | 11.08 | 16 | 664527 | 11252 | 46010267 |
Contraindication to medical treatment | 107.16 | 11.08 | 80 | 664463 | 523 | 46020996 |
Nightmare | 107.10 | 11.08 | 51 | 664492 | 16547 | 46004972 |
Lymphocyte count decreased | 106.67 | 11.08 | 124 | 664419 | 25465 | 45996054 |
Pruritus | 106.14 | 11.08 | 2632 | 661911 | 239720 | 45781799 |
Circulatory collapse | 105.95 | 11.08 | 91 | 664452 | 21533 | 45999986 |
Abortion spontaneous | 105.89 | 11.08 | 296 | 664247 | 43350 | 45978169 |
Myoclonus | 105.82 | 11.08 | 36 | 664507 | 14316 | 46007203 |
Melaena | 104.93 | 11.08 | 145 | 664398 | 27627 | 45993892 |
Blood sodium decreased | 104.54 | 11.08 | 93 | 664450 | 21633 | 45999886 |
Rash maculo-papular | 103.86 | 11.08 | 147 | 664396 | 27727 | 45993792 |
Shoulder arthroplasty | 103.10 | 11.08 | 170 | 664373 | 2938 | 46018581 |
Adverse drug reaction | 103.10 | 11.08 | 1025 | 663518 | 43337 | 45978182 |
Dysarthria | 102.79 | 11.08 | 239 | 664304 | 37259 | 45984260 |
Anhedonia | 102.58 | 11.08 | 13 | 664530 | 10322 | 46011197 |
Acute myocardial infarction | 102.32 | 11.08 | 186 | 664357 | 31738 | 45989781 |
Speech disorder | 102.00 | 11.08 | 227 | 664316 | 35940 | 45985579 |
Mycobacterium tuberculosis complex test positive | 101.88 | 11.08 | 119 | 664424 | 1459 | 46020060 |
Acute respiratory failure | 101.45 | 11.08 | 161 | 664382 | 28977 | 45992542 |
Dystonia | 100.74 | 11.08 | 19 | 664524 | 11238 | 46010281 |
Impaired healing | 99.95 | 11.08 | 878 | 663665 | 35865 | 45985654 |
Demyelination | 99.83 | 11.08 | 238 | 664305 | 5442 | 46016077 |
Immunosuppression | 99.67 | 11.08 | 283 | 664260 | 7217 | 46014302 |
Venoocclusive liver disease | 99.63 | 11.08 | 200 | 664343 | 4051 | 46017468 |
Polyarthritis | 99.08 | 11.08 | 259 | 664284 | 6283 | 46015236 |
Memory impairment | 98.79 | 11.08 | 669 | 663874 | 76668 | 45944851 |
Drug clearance decreased | 98.60 | 11.08 | 98 | 664445 | 986 | 46020533 |
Oral herpes | 98.48 | 11.08 | 540 | 664003 | 18850 | 46002669 |
Latent tuberculosis | 96.43 | 11.08 | 129 | 664414 | 1831 | 46019688 |
Transfusion | 96.15 | 11.08 | 34 | 664509 | 13197 | 46008322 |
Joint arthroplasty | 96.06 | 11.08 | 131 | 664412 | 1896 | 46019623 |
Blood bilirubin increased | 96.03 | 11.08 | 215 | 664328 | 33969 | 45987550 |
Graft versus host disease | 95.90 | 11.08 | 257 | 664286 | 6331 | 46015188 |
Mania | 95.59 | 11.08 | 19 | 664524 | 10827 | 46010692 |
Cholecystitis chronic | 95.51 | 11.08 | 17 | 664526 | 10482 | 46011037 |
Paraesthesia | 94.72 | 11.08 | 1142 | 663401 | 116295 | 45905224 |
Upper gastrointestinal haemorrhage | 94.17 | 11.08 | 61 | 664482 | 16677 | 46004842 |
Bone marrow failure | 94.11 | 11.08 | 734 | 663809 | 28935 | 45992584 |
Peritonitis bacterial | 93.31 | 11.08 | 8 | 664535 | 8645 | 46012874 |
Sensitivity to weather change | 92.53 | 11.08 | 227 | 664316 | 5289 | 46016230 |
Jaundice | 92.50 | 11.08 | 168 | 664375 | 28677 | 45992842 |
Deafness transitory | 92.18 | 11.08 | 115 | 664428 | 1517 | 46020002 |
Blood glucose decreased | 91.95 | 11.08 | 80 | 664463 | 18812 | 46002707 |
Tubulointerstitial nephritis | 91.56 | 11.08 | 48 | 664495 | 14740 | 46006779 |
Foot operation | 91.51 | 11.08 | 206 | 664337 | 4531 | 46016988 |
Sinus tachycardia | 91.22 | 11.08 | 104 | 664439 | 21545 | 45999974 |
Cardiac disorder | 91.18 | 11.08 | 319 | 664224 | 43539 | 45977980 |
Thrombocytopenia | 89.92 | 11.08 | 1264 | 663279 | 125317 | 45896202 |
Thrombosis | 89.21 | 11.08 | 452 | 664091 | 55617 | 45965902 |
Hypothermia | 89.06 | 11.08 | 31 | 664512 | 12152 | 46009367 |
X-ray abnormal | 88.88 | 11.08 | 97 | 664446 | 1098 | 46020421 |
Muscle twitching | 88.83 | 11.08 | 49 | 664494 | 14623 | 46006896 |
Immobile | 87.52 | 11.08 | 199 | 664344 | 4407 | 46017112 |
Altered state of consciousness | 87.12 | 11.08 | 123 | 664420 | 23225 | 45998294 |
Haemorrhage | 86.91 | 11.08 | 443 | 664100 | 54426 | 45967093 |
Abdominal distension | 86.63 | 11.08 | 649 | 663894 | 72702 | 45948817 |
Injection site haemorrhage | 86.62 | 11.08 | 548 | 663995 | 20161 | 46001358 |
Bone pain | 86.51 | 11.08 | 358 | 664185 | 46532 | 45974987 |
Premature labour | 85.66 | 11.08 | 27 | 664516 | 11272 | 46010247 |
Neoplasm progression | 85.04 | 11.08 | 156 | 664387 | 26527 | 45994992 |
Electrolyte imbalance | 84.99 | 11.08 | 72 | 664471 | 17154 | 46004365 |
Schizophrenia | 84.51 | 11.08 | 11 | 664532 | 8557 | 46012962 |
Presyncope | 84.31 | 11.08 | 136 | 664407 | 24318 | 45997201 |
Chronic obstructive pulmonary disease | 84.27 | 11.08 | 478 | 664065 | 57155 | 45964364 |
Akathisia | 83.54 | 11.08 | 7 | 664536 | 7707 | 46013812 |
Hodgkin's disease | 83.37 | 11.08 | 80 | 664463 | 768 | 46020751 |
Blood calcium decreased | 83.01 | 11.08 | 61 | 664482 | 15612 | 46005907 |
Delusion | 82.59 | 11.08 | 28 | 664515 | 11160 | 46010359 |
Product substitution issue | 81.58 | 11.08 | 57 | 664486 | 14974 | 46006545 |
Cardiogenic shock | 81.43 | 11.08 | 68 | 664475 | 16316 | 46005203 |
Parkinsonism | 81.36 | 11.08 | 9 | 664534 | 7939 | 46013580 |
Head injury | 81.24 | 11.08 | 141 | 664402 | 24495 | 45997024 |
Localised infection | 80.63 | 11.08 | 598 | 663945 | 23203 | 45998316 |
Elbow deformity | 80.19 | 11.08 | 98 | 664445 | 1264 | 46020255 |
Flatulence | 80.01 | 11.08 | 183 | 664360 | 28695 | 45992824 |
Haematocrit decreased | 79.07 | 11.08 | 246 | 664297 | 34811 | 45986708 |
Limb deformity | 77.62 | 11.08 | 163 | 664380 | 3413 | 46018106 |
Mucosal ulceration | 77.45 | 11.08 | 79 | 664464 | 822 | 46020697 |
Stevens-Johnson syndrome | 77.13 | 11.08 | 133 | 664410 | 23164 | 45998355 |
Wound | 76.96 | 11.08 | 940 | 663603 | 41862 | 45979657 |
Synovial cyst | 76.90 | 11.08 | 255 | 664288 | 7091 | 46014428 |
Therapy non-responder | 75.40 | 11.08 | 907 | 663636 | 40245 | 45981274 |
Muscle rigidity | 75.17 | 11.08 | 24 | 664519 | 9937 | 46011582 |
Breast cancer stage III | 74.99 | 11.08 | 95 | 664448 | 1274 | 46020245 |
Pericarditis | 74.81 | 11.08 | 590 | 663953 | 23337 | 45998182 |
Mental disorder | 74.27 | 11.08 | 128 | 664415 | 22297 | 45999222 |
Swollen tongue | 74.10 | 11.08 | 194 | 664349 | 29038 | 45992481 |
Musculoskeletal deformity | 74.10 | 11.08 | 73 | 664470 | 726 | 46020793 |
Paranoia | 74.03 | 11.08 | 29 | 664514 | 10568 | 46010951 |
Dry skin | 73.90 | 11.08 | 316 | 664227 | 40700 | 45980819 |
Status epilepticus | 73.27 | 11.08 | 55 | 664488 | 13924 | 46007595 |
Hypofibrinogenaemia | 72.96 | 11.08 | 83 | 664460 | 987 | 46020532 |
Hepatotoxicity | 72.95 | 11.08 | 607 | 663936 | 24402 | 45997117 |
Urinary incontinence | 72.58 | 11.08 | 189 | 664354 | 28341 | 45993178 |
Complication associated with device | 72.03 | 11.08 | 68 | 664475 | 15373 | 46006146 |
Abnormal dreams | 72.03 | 11.08 | 28 | 664515 | 10251 | 46011268 |
Spinal stenosis | 71.73 | 11.08 | 361 | 664182 | 12182 | 46009337 |
Tardive dyskinesia | 71.31 | 11.08 | 11 | 664532 | 7532 | 46013987 |
Joint dislocation | 71.21 | 11.08 | 332 | 664211 | 10854 | 46010665 |
Hallucination, auditory | 71.02 | 11.08 | 32 | 664511 | 10724 | 46010795 |
Pharyngitis | 70.90 | 11.08 | 461 | 664082 | 17122 | 46004397 |
Urinary tract infection | 70.90 | 11.08 | 2494 | 662049 | 217772 | 45803747 |
Histoplasmosis | 70.86 | 11.08 | 103 | 664440 | 1587 | 46019932 |
Hypersensitivity | 70.74 | 11.08 | 2712 | 661831 | 147609 | 45873910 |
Lip swelling | 70.29 | 11.08 | 161 | 664382 | 25234 | 45996285 |
Uterine perforation | 70.08 | 11.08 | 10 | 664533 | 7257 | 46014262 |
Cerebral haemorrhage | 69.86 | 11.08 | 191 | 664352 | 28180 | 45993339 |
Off label use | 69.40 | 11.08 | 6292 | 658251 | 373549 | 45647970 |
Respiratory failure | 69.39 | 11.08 | 941 | 663602 | 93875 | 45927644 |
Chills | 69.23 | 11.08 | 956 | 663587 | 95076 | 45926443 |
Feeling abnormal | 69.19 | 11.08 | 1308 | 663235 | 123752 | 45897767 |
Pneumonitis | 69.13 | 11.08 | 663 | 663880 | 27757 | 45993762 |
Haematemesis | 68.66 | 11.08 | 197 | 664346 | 28609 | 45992910 |
Skin cancer | 68.51 | 11.08 | 278 | 664265 | 8545 | 46012974 |
Ulcer | 68.31 | 11.08 | 453 | 664090 | 16939 | 46004580 |
Aphthous ulcer | 68.01 | 11.08 | 293 | 664250 | 9255 | 46012264 |
Retinal toxicity | 67.75 | 11.08 | 80 | 664463 | 993 | 46020526 |
Bronchitis chronic | 67.28 | 11.08 | 169 | 664374 | 3998 | 46017521 |
Granuloma skin | 67.14 | 11.08 | 151 | 664392 | 3319 | 46018200 |
Blood count abnormal | 66.88 | 11.08 | 94 | 664449 | 17784 | 46003735 |
Red blood cell count decreased | 66.66 | 11.08 | 239 | 664304 | 32384 | 45989135 |
Respiratory distress | 66.43 | 11.08 | 232 | 664311 | 31684 | 45989835 |
Drug tolerance decreased | 65.89 | 11.08 | 139 | 664404 | 2920 | 46018599 |
Injection site rash | 65.86 | 11.08 | 418 | 664125 | 15395 | 46006124 |
Myelopathy | 65.81 | 11.08 | 125 | 664418 | 2427 | 46019092 |
Ventricular extrasystoles | 65.46 | 11.08 | 38 | 664505 | 11025 | 46010494 |
Infusion site pain | 65.29 | 11.08 | 31 | 664512 | 10076 | 46011443 |
Atrial septal defect | 65.25 | 11.08 | 7 | 664536 | 6325 | 46015194 |
Hypertension | 65.09 | 11.08 | 2215 | 662328 | 194141 | 45827378 |
Leukocytosis | 65.04 | 11.08 | 148 | 664395 | 23250 | 45998269 |
Electrocardiogram QRS complex prolonged | 64.81 | 11.08 | 3 | 664540 | 5446 | 46016073 |
Haematoma | 64.79 | 11.08 | 234 | 664309 | 31638 | 45989881 |
Blood magnesium decreased | 64.70 | 11.08 | 38 | 664505 | 10954 | 46010565 |
Sleep disorder | 64.57 | 11.08 | 980 | 663563 | 45815 | 45975704 |
Epilepsy | 64.49 | 11.08 | 152 | 664391 | 23586 | 45997933 |
Atrioventricular block | 64.24 | 11.08 | 10 | 664533 | 6801 | 46014718 |
Neutropenia | 64.02 | 11.08 | 1550 | 662993 | 141654 | 45879865 |
Injection site urticaria | 63.97 | 11.08 | 338 | 664205 | 11629 | 46009890 |
Oxygen saturation decreased | 63.90 | 11.08 | 652 | 663891 | 68512 | 45953007 |
Fear | 63.57 | 11.08 | 82 | 664461 | 16090 | 46005429 |
Acute lymphocytic leukaemia recurrent | 63.41 | 11.08 | 110 | 664433 | 1985 | 46019534 |
Tricuspid valve incompetence | 63.30 | 11.08 | 61 | 664482 | 13656 | 46007863 |
Joint injury | 63.02 | 11.08 | 479 | 664064 | 18730 | 46002789 |
Hospice care | 62.70 | 11.08 | 3 | 664540 | 5292 | 46016227 |
Lymph node tuberculosis | 62.61 | 11.08 | 66 | 664477 | 716 | 46020803 |
Gamma-glutamyltransferase increased | 62.57 | 11.08 | 236 | 664307 | 31504 | 45990015 |
Enthesopathy | 62.35 | 11.08 | 177 | 664366 | 4513 | 46017006 |
Epidermal necrosis | 62.22 | 11.08 | 68 | 664475 | 771 | 46020748 |
Product administration error | 61.89 | 11.08 | 116 | 664427 | 19565 | 46001954 |
Cyanosis | 61.74 | 11.08 | 82 | 664461 | 15889 | 46005630 |
Acute hepatic failure | 61.72 | 11.08 | 71 | 664472 | 14650 | 46006869 |
Mucocutaneous ulceration | 61.71 | 11.08 | 35 | 664508 | 131 | 46021388 |
Depressed mood | 61.70 | 11.08 | 254 | 664289 | 33065 | 45988454 |
Product complaint | 61.66 | 11.08 | 49 | 664494 | 12052 | 46009467 |
Transient ischaemic attack | 61.60 | 11.08 | 271 | 664272 | 34632 | 45986887 |
Ear infection | 61.59 | 11.08 | 548 | 663995 | 22465 | 45999054 |
Body height below normal | 61.56 | 11.08 | 101 | 664442 | 1738 | 46019781 |
Atrioventricular block first degree | 60.87 | 11.08 | 8 | 664535 | 6178 | 46015341 |
Eosinophilia | 60.66 | 11.08 | 113 | 664430 | 19104 | 46002415 |
Dementia | 60.47 | 11.08 | 74 | 664469 | 14856 | 46006663 |
Obstructive airways disorder | 60.33 | 11.08 | 61 | 664482 | 13351 | 46008168 |
Generalised tonic-clonic seizure | 59.98 | 11.08 | 192 | 664351 | 26930 | 45994589 |
Neck pain | 59.73 | 11.08 | 1113 | 663430 | 54193 | 45967326 |
Pleural effusion | 59.71 | 11.08 | 826 | 663717 | 82126 | 45939393 |
No adverse event | 59.68 | 11.08 | 267 | 664276 | 33964 | 45987555 |
Hepatic steatosis | 59.53 | 11.08 | 563 | 663980 | 23479 | 45998040 |
Dialysis | 59.50 | 11.08 | 35 | 664508 | 10081 | 46011438 |
Rheumatoid factor negative | 59.46 | 11.08 | 55 | 664488 | 502 | 46021017 |
Investigation abnormal | 59.32 | 11.08 | 74 | 664469 | 976 | 46020543 |
Renal injury | 59.02 | 11.08 | 31 | 664512 | 9510 | 46012009 |
Rectal haemorrhage | 58.81 | 11.08 | 312 | 664231 | 37943 | 45983576 |
Epicondylitis | 58.75 | 11.08 | 96 | 664447 | 1646 | 46019873 |
Nervousness | 58.59 | 11.08 | 208 | 664335 | 28267 | 45993252 |
Diabetes mellitus inadequate control | 58.42 | 11.08 | 61 | 664482 | 13153 | 46008366 |
Infusion site erythema | 58.40 | 11.08 | 18 | 664525 | 7624 | 46013895 |
Face oedema | 58.38 | 11.08 | 115 | 664428 | 19038 | 46002481 |
Haemoptysis | 58.19 | 11.08 | 185 | 664358 | 26004 | 45995515 |
Tonsillitis | 58.05 | 11.08 | 179 | 664364 | 4785 | 46016734 |
Rash | 57.31 | 11.08 | 5853 | 658690 | 350659 | 45670860 |
Chromaturia | 57.15 | 11.08 | 78 | 664465 | 14941 | 46006578 |
Liver function test abnormal | 57.15 | 11.08 | 955 | 663588 | 45532 | 45975987 |
Wrist deformity | 56.93 | 11.08 | 88 | 664455 | 1436 | 46020083 |
Neuroendocrine carcinoma of the skin | 56.73 | 11.08 | 49 | 664494 | 405 | 46021114 |
Treatment noncompliance | 56.72 | 11.08 | 224 | 664319 | 29507 | 45992012 |
Onychomycosis | 56.69 | 11.08 | 158 | 664385 | 3985 | 46017534 |
Sarcoidosis | 56.63 | 11.08 | 182 | 664361 | 4977 | 46016542 |
Ascites | 56.45 | 11.08 | 298 | 664245 | 36286 | 45985233 |
Pallor | 56.27 | 11.08 | 157 | 664386 | 23009 | 45998510 |
Somnambulism | 56.16 | 11.08 | 4 | 664539 | 5033 | 46016486 |
Acute generalised exanthematous pustulosis | 56.08 | 11.08 | 32 | 664511 | 9373 | 46012146 |
Mydriasis | 55.99 | 11.08 | 41 | 664502 | 10512 | 46011007 |
General physical health deterioration | 55.95 | 11.08 | 1238 | 663305 | 114531 | 45906988 |
Hepatic encephalopathy | 55.81 | 11.08 | 38 | 664505 | 10119 | 46011400 |
Seronegative arthritis | 55.73 | 11.08 | 61 | 664482 | 693 | 46020826 |
Scleritis | 55.54 | 11.08 | 126 | 664417 | 2786 | 46018733 |
Transplant rejection | 55.32 | 11.08 | 34 | 664509 | 9562 | 46011957 |
Wrist surgery | 55.22 | 11.08 | 62 | 664481 | 726 | 46020793 |
Gestational diabetes | 55.18 | 11.08 | 17 | 664526 | 7202 | 46014317 |
Complication of device insertion | 54.91 | 11.08 | 4 | 664539 | 4940 | 46016579 |
Eye disorder | 54.90 | 11.08 | 444 | 664099 | 17697 | 46003822 |
Product physical issue | 54.68 | 11.08 | 4 | 664539 | 4923 | 46016596 |
Aspartate aminotransferase increased | 54.40 | 11.08 | 790 | 663753 | 77910 | 45943609 |
Joint noise | 54.36 | 11.08 | 132 | 664411 | 3055 | 46018464 |
Ankle deformity | 54.32 | 11.08 | 46 | 664497 | 369 | 46021150 |
Pneumonia legionella | 53.98 | 11.08 | 81 | 664462 | 1286 | 46020233 |
SLE arthritis | 53.94 | 11.08 | 55 | 664488 | 572 | 46020947 |
Acute graft versus host disease in intestine | 53.94 | 11.08 | 91 | 664452 | 1604 | 46019915 |
Inflammatory marker increased | 53.74 | 11.08 | 186 | 664357 | 5289 | 46016230 |
Incorrect product administration duration | 53.74 | 11.08 | 35 | 664508 | 9542 | 46011977 |
Mood altered | 53.17 | 11.08 | 64 | 664479 | 12943 | 46008576 |
Tinnitus | 53.11 | 11.08 | 208 | 664335 | 27465 | 45994054 |
Swelling face | 52.88 | 11.08 | 491 | 664052 | 52568 | 45968951 |
Drug dependence | 52.82 | 11.08 | 129 | 664414 | 19772 | 46001747 |
Atypical mycobacterial infection | 52.80 | 11.08 | 65 | 664478 | 845 | 46020674 |
Pulseless electrical activity | 52.80 | 11.08 | 18 | 664525 | 7149 | 46014370 |
Retching | 52.58 | 11.08 | 65 | 664478 | 12992 | 46008527 |
Anuria | 52.55 | 11.08 | 51 | 664492 | 11380 | 46010139 |
Visceral leishmaniasis | 52.54 | 11.08 | 47 | 664496 | 409 | 46021110 |
Epstein-Barr virus associated lymphoma | 52.48 | 11.08 | 39 | 664504 | 253 | 46021266 |
Pre-eclampsia | 52.44 | 11.08 | 24 | 664519 | 7970 | 46013549 |
Acidosis | 52.37 | 11.08 | 49 | 664494 | 11125 | 46010394 |
Blood parathyroid hormone decreased | 52.19 | 11.08 | 159 | 664384 | 4222 | 46017297 |
Stillbirth | 51.98 | 11.08 | 14 | 664529 | 6477 | 46015042 |
Unevaluable event | 51.95 | 11.08 | 414 | 664129 | 45761 | 45975758 |
Blood pressure fluctuation | 51.86 | 11.08 | 662 | 663881 | 29786 | 45991733 |
Renal tubular necrosis | 51.83 | 11.08 | 46 | 664497 | 10713 | 46010806 |
Forced expiratory volume decreased | 51.69 | 11.08 | 6 | 664537 | 5098 | 46016421 |
Creatinine renal clearance decreased | 51.64 | 11.08 | 17 | 664526 | 6903 | 46014616 |
Non-Hodgkin's lymphoma | 51.55 | 11.08 | 85 | 664458 | 1469 | 46020050 |
Psychomotor hyperactivity | 51.45 | 11.08 | 37 | 664506 | 9576 | 46011943 |
Pollakiuria | 51.41 | 11.08 | 175 | 664368 | 24086 | 45997433 |
Transaminases increased | 51.35 | 11.08 | 613 | 663930 | 27148 | 45994371 |
Wrong technique in product usage process | 51.11 | 11.08 | 511 | 664032 | 53911 | 45967608 |
Dysuria | 51.02 | 11.08 | 213 | 664330 | 27620 | 45993899 |
Inappropriate antidiuretic hormone secretion | 50.93 | 11.08 | 76 | 664467 | 14026 | 46007493 |
Osteonecrosis of jaw | 50.46 | 11.08 | 285 | 664258 | 34117 | 45987402 |
Graft versus host disease in skin | 50.34 | 11.08 | 107 | 664436 | 2260 | 46019259 |
Lip ulceration | 50.24 | 11.08 | 89 | 664454 | 1634 | 46019885 |
Foetal methotrexate syndrome | 50.20 | 11.08 | 23 | 664520 | 47 | 46021472 |
Bronchitis | 50.06 | 11.08 | 1913 | 662630 | 104066 | 45917453 |
Hot flush | 49.97 | 11.08 | 388 | 664155 | 43129 | 45978390 |
Sleep apnoea syndrome | 49.91 | 11.08 | 156 | 664387 | 22045 | 45999474 |
Pleurisy | 49.87 | 11.08 | 231 | 664312 | 7531 | 46013988 |
Lennox-Gastaut syndrome | 49.79 | 11.08 | 37 | 664506 | 240 | 46021279 |
Ventricular fibrillation | 49.78 | 11.08 | 54 | 664489 | 11442 | 46010077 |
Ageusia | 49.55 | 11.08 | 54 | 664489 | 11418 | 46010101 |
Skin necrosis | 49.46 | 11.08 | 248 | 664295 | 8356 | 46013163 |
Ejection fraction decreased | 49.42 | 11.08 | 114 | 664429 | 17823 | 46003696 |
Supraventricular tachycardia | 49.41 | 11.08 | 70 | 664473 | 13200 | 46008319 |
Pregnancy with contraceptive device | 49.00 | 11.08 | 4 | 664539 | 4499 | 46017020 |
Lung adenocarcinoma | 48.61 | 11.08 | 151 | 664392 | 4053 | 46017466 |
Synovectomy | 48.54 | 11.08 | 31 | 664512 | 151 | 46021368 |
Hepatosplenic T-cell lymphoma | 48.50 | 11.08 | 52 | 664491 | 576 | 46020943 |
Hypothyroidism | 48.50 | 11.08 | 255 | 664288 | 31083 | 45990436 |
Thinking abnormal | 48.44 | 11.08 | 41 | 664502 | 9773 | 46011746 |
Blood loss anaemia | 48.39 | 11.08 | 31 | 664512 | 8526 | 46012993 |
Toxic epidermal necrolysis | 48.37 | 11.08 | 159 | 664384 | 22119 | 45999400 |
Surgical failure | 47.97 | 11.08 | 64 | 664479 | 906 | 46020613 |
Neurotoxicity | 47.81 | 11.08 | 347 | 664196 | 13370 | 46008149 |
Hyperlipidaemia | 47.78 | 11.08 | 122 | 664421 | 18417 | 46003102 |
Rheumatoid factor increased | 47.75 | 11.08 | 77 | 664466 | 1305 | 46020214 |
Haemorrhage intracranial | 47.50 | 11.08 | 67 | 664476 | 12657 | 46008862 |
Blood potassium increased | 47.42 | 11.08 | 107 | 664436 | 16860 | 46004659 |
Shock | 47.36 | 11.08 | 156 | 664387 | 21689 | 45999830 |
Rheumatic disorder | 47.22 | 11.08 | 78 | 664465 | 1350 | 46020169 |
Device breakage | 47.22 | 11.08 | 41 | 664502 | 9651 | 46011868 |
Chronic graft versus host disease in skin | 47.16 | 11.08 | 51 | 664492 | 571 | 46020948 |
Bradyphrenia | 47.03 | 11.08 | 15 | 664528 | 6215 | 46015304 |
Spinal column injury | 46.99 | 11.08 | 89 | 664454 | 1724 | 46019795 |
Mycobacterium marinum infection | 46.84 | 11.08 | 27 | 664516 | 105 | 46021414 |
Hepatic fibrosis | 46.82 | 11.08 | 120 | 664423 | 2875 | 46018644 |
Hypovolaemia | 46.77 | 11.08 | 43 | 664500 | 9845 | 46011674 |
Device use error | 46.71 | 11.08 | 8 | 664535 | 5073 | 46016446 |
Heparin-induced thrombocytopenia | 46.42 | 11.08 | 4 | 664539 | 4305 | 46017214 |
Infusion site swelling | 46.19 | 11.08 | 12 | 664531 | 5687 | 46015832 |
Respiratory acidosis | 46.06 | 11.08 | 15 | 664528 | 6133 | 46015386 |
Sciatica | 45.90 | 11.08 | 443 | 664100 | 18577 | 46002942 |
Hepatitis E | 45.52 | 11.08 | 71 | 664472 | 1168 | 46020351 |
Ovarian neoplasm | 45.51 | 11.08 | 57 | 664486 | 755 | 46020764 |
Dermatitis allergic | 45.18 | 11.08 | 321 | 664222 | 12282 | 46009237 |
Temporal lobe epilepsy | 45.17 | 11.08 | 40 | 664503 | 343 | 46021176 |
Dislocation of vertebra | 45.15 | 11.08 | 73 | 664470 | 1240 | 46020279 |
Glycosylated haemoglobin increased | 45.01 | 11.08 | 53 | 664490 | 10823 | 46010696 |
Oral mucosal exfoliation | 45.00 | 11.08 | 80 | 664463 | 1473 | 46020046 |
Multiple sclerosis | 44.66 | 11.08 | 191 | 664352 | 24600 | 45996919 |
Metabolic encephalopathy | 44.52 | 11.08 | 11 | 664532 | 5392 | 46016127 |
Salivary hypersecretion | 44.43 | 11.08 | 18 | 664525 | 6427 | 46015092 |
Nasal ulcer | 44.09 | 11.08 | 76 | 664467 | 1364 | 46020155 |
Liver disorder | 43.90 | 11.08 | 760 | 663783 | 36486 | 45985033 |
Adenovirus infection | 43.84 | 11.08 | 113 | 664430 | 2717 | 46018802 |
Anger | 43.66 | 11.08 | 63 | 664480 | 11789 | 46009730 |
Cytokine release syndrome | 43.52 | 11.08 | 17 | 664526 | 6206 | 46015313 |
Transaminases abnormal | 43.50 | 11.08 | 46 | 664497 | 501 | 46021018 |
Amyotrophic lateral sclerosis | 43.43 | 11.08 | 64 | 664479 | 999 | 46020520 |
Eye swelling | 43.28 | 11.08 | 144 | 664399 | 19959 | 46001560 |
Varicella zoster virus infection | 43.16 | 11.08 | 100 | 664443 | 2243 | 46019276 |
Hypercapnia | 43.16 | 11.08 | 7 | 664536 | 4619 | 46016900 |
Cutaneous vasculitis | 43.09 | 11.08 | 140 | 664403 | 3851 | 46017668 |
Skin erosion | 43.03 | 11.08 | 99 | 664444 | 2210 | 46019309 |
Pneumonia cryptococcal | 43 | 11.08 | 47 | 664496 | 533 | 46020986 |
Gastrointestinal pain | 42.94 | 11.08 | 215 | 664328 | 7240 | 46014279 |
Renal impairment | 42.94 | 11.08 | 772 | 663771 | 73600 | 45947919 |
Organising pneumonia | 42.56 | 11.08 | 160 | 664383 | 4742 | 46016777 |
Atrioventricular block second degree | 42.40 | 11.08 | 3 | 664540 | 3796 | 46017723 |
Encephalitis | 42.33 | 11.08 | 214 | 664329 | 7234 | 46014285 |
Ill-defined disorder | 42.24 | 11.08 | 575 | 663968 | 26252 | 45995267 |
Panic attack | 42.22 | 11.08 | 147 | 664396 | 20095 | 46001424 |
Vascular access complication | 42.15 | 11.08 | 60 | 664483 | 906 | 46020613 |
Glaucoma | 42.03 | 11.08 | 378 | 664165 | 15543 | 46005976 |
Bradykinesia | 41.87 | 11.08 | 4 | 664539 | 3962 | 46017557 |
Human antichimeric antibody positive | 41.86 | 11.08 | 73 | 664470 | 1323 | 46020196 |
Malignant respiratory tract neoplasm | 41.82 | 11.08 | 20 | 664523 | 47 | 46021472 |
Muscle tightness | 41.81 | 11.08 | 51 | 664492 | 10254 | 46011265 |
Pyrexia | 41.66 | 11.08 | 4338 | 660205 | 344464 | 45677055 |
Erythema multiforme | 41.56 | 11.08 | 46 | 664497 | 9658 | 46011861 |
Coordination abnormal | 41.53 | 11.08 | 57 | 664486 | 10892 | 46010627 |
Spondyloarthropathy | 41.25 | 11.08 | 50 | 664493 | 639 | 46020880 |
Hypophosphataemia | 41.23 | 11.08 | 27 | 664516 | 7340 | 46014179 |
Genital haemorrhage | 41.11 | 11.08 | 21 | 664522 | 6545 | 46014974 |
Hypoaesthesia oral | 41.03 | 11.08 | 54 | 664489 | 10505 | 46011014 |
Drug screen positive | 40.88 | 11.08 | 4 | 664539 | 3887 | 46017632 |
Complications of bone marrow transplant | 40.84 | 11.08 | 41 | 664502 | 418 | 46021101 |
Ankle arthroplasty | 40.75 | 11.08 | 47 | 664496 | 568 | 46020951 |
Tenderness | 40.65 | 11.08 | 393 | 664150 | 16488 | 46005031 |
Lung neoplasm malignant | 40.51 | 11.08 | 367 | 664176 | 15122 | 46006397 |
Muscular weakness | 40.50 | 11.08 | 996 | 663547 | 90848 | 45930671 |
Vertigo | 40.47 | 11.08 | 510 | 664033 | 51538 | 45969981 |
Secretion discharge | 40.46 | 11.08 | 247 | 664296 | 8972 | 46012547 |
Cholestasis | 40.42 | 11.08 | 221 | 664322 | 26672 | 45994847 |
Headache | 40.11 | 11.08 | 6087 | 658456 | 472265 | 45549254 |
Device difficult to use | 40.05 | 11.08 | 33 | 664510 | 7971 | 46013548 |
Urine output decreased | 39.89 | 11.08 | 60 | 664483 | 11037 | 46010482 |
Leukopenia | 39.85 | 11.08 | 1264 | 663279 | 67079 | 45954440 |
Prothrombin time prolonged | 39.46 | 11.08 | 47 | 664496 | 9549 | 46011970 |
Joint laxity | 39.21 | 11.08 | 90 | 664453 | 2006 | 46019513 |
Blood pressure systolic abnormal | 39.06 | 11.08 | 169 | 664374 | 5348 | 46016171 |
Foetal death | 39.06 | 11.08 | 40 | 664503 | 8703 | 46012816 |
Hyperreflexia | 39.04 | 11.08 | 13 | 664530 | 5241 | 46016278 |
Tachypnoea | 38.90 | 11.08 | 92 | 664451 | 14259 | 46007260 |
Hereditary angioedema | 38.69 | 11.08 | 15 | 664528 | 5501 | 46016018 |
Extranodal marginal zone B-cell lymphoma (MALT type) | 38.65 | 11.08 | 40 | 664503 | 424 | 46021095 |
Cholelithiasis | 38.52 | 11.08 | 358 | 664185 | 38323 | 45983196 |
Application site erythema | 38.48 | 11.08 | 11 | 664532 | 4893 | 46016626 |
Dizziness postural | 38.34 | 11.08 | 22 | 664521 | 6424 | 46015095 |
Physical disability | 38.32 | 11.08 | 83 | 664460 | 1777 | 46019742 |
Lower gastrointestinal haemorrhage | 38.11 | 11.08 | 29 | 664514 | 7291 | 46014228 |
Thyroid neoplasm | 38.08 | 11.08 | 127 | 664416 | 3542 | 46017977 |
Blood pressure diastolic abnormal | 38.02 | 11.08 | 184 | 664359 | 6110 | 46015409 |
Peritoneal tuberculosis | 37.88 | 11.08 | 43 | 664500 | 510 | 46021009 |
Acute coronary syndrome | 37.82 | 11.08 | 54 | 664489 | 10150 | 46011369 |
Aspiration | 37.80 | 11.08 | 48 | 664495 | 9483 | 46012036 |
Cardiomegaly | 37.79 | 11.08 | 125 | 664418 | 17357 | 46004162 |
Low birth weight baby | 37.75 | 11.08 | 15 | 664528 | 5419 | 46016100 |
Graft versus host disease in gastrointestinal tract | 37.64 | 11.08 | 100 | 664443 | 2450 | 46019069 |
Alveolitis | 37.56 | 11.08 | 99 | 664444 | 2414 | 46019105 |
Faecaloma | 37.52 | 11.08 | 33 | 664510 | 7719 | 46013800 |
Atrioventricular block complete | 37.48 | 11.08 | 32 | 664511 | 7595 | 46013924 |
Neutrophil count increased | 37.35 | 11.08 | 93 | 664450 | 14160 | 46007359 |
Iritis | 37.33 | 11.08 | 95 | 664448 | 2266 | 46019253 |
Posterior reversible encephalopathy syndrome | 37.20 | 11.08 | 354 | 664189 | 14787 | 46006732 |
Unintended pregnancy | 37.12 | 11.08 | 17 | 664526 | 5643 | 46015876 |
Maternal drugs affecting foetus | 37.09 | 11.08 | 16 | 664527 | 5502 | 46016017 |
Epstein-Barr viraemia | 37.02 | 11.08 | 49 | 664494 | 688 | 46020831 |
Hypersensitivity pneumonitis | 37.02 | 11.08 | 95 | 664448 | 2278 | 46019241 |
Faeces discoloured | 37.00 | 11.08 | 119 | 664424 | 16668 | 46004851 |
Central nervous system lymphoma | 36.86 | 11.08 | 65 | 664478 | 1189 | 46020330 |
Skin exfoliation | 36.74 | 11.08 | 296 | 664247 | 32642 | 45988877 |
Catatonia | 36.70 | 11.08 | 5 | 664538 | 3757 | 46017762 |
Viral upper respiratory tract infection | 36.68 | 11.08 | 197 | 664346 | 6821 | 46014698 |
Mitral valve incompetence | 36.62 | 11.08 | 141 | 664402 | 18711 | 46002808 |
Amnesia | 36.59 | 11.08 | 397 | 664146 | 41234 | 45980285 |
Arthritis infective | 36.49 | 11.08 | 157 | 664386 | 4956 | 46016563 |
Paraesthesia oral | 36.48 | 11.08 | 70 | 664473 | 11703 | 46009816 |
Atrial flutter | 36.36 | 11.08 | 46 | 664497 | 9102 | 46012417 |
Synovial disorder | 36.30 | 11.08 | 52 | 664491 | 790 | 46020729 |
Subdural haematoma | 36.29 | 11.08 | 82 | 664461 | 12915 | 46008604 |
Hip fracture | 36.29 | 11.08 | 225 | 664318 | 26331 | 45995188 |
Mental impairment | 36.09 | 11.08 | 77 | 664466 | 12379 | 46009140 |
Pneumonia viral | 36.03 | 11.08 | 188 | 664355 | 6436 | 46015083 |
Haematuria | 35.96 | 11.08 | 229 | 664314 | 26629 | 45994890 |
Oropharyngeal pain | 35.78 | 11.08 | 1342 | 663201 | 72826 | 45948693 |
Product preparation error | 35.75 | 11.08 | 7 | 664536 | 4032 | 46017487 |
Metastases to bone | 35.72 | 11.08 | 128 | 664415 | 17348 | 46004171 |
Patent ductus arteriosus | 35.68 | 11.08 | 6 | 664537 | 3856 | 46017663 |
Synostosis | 35.53 | 11.08 | 17 | 664526 | 40 | 46021479 |
Abortion incomplete | 35.24 | 11.08 | 3 | 664540 | 3261 | 46018258 |
Adult T-cell lymphoma/leukaemia | 35.02 | 11.08 | 33 | 664510 | 309 | 46021210 |
Squamous cell carcinoma of lung | 34.98 | 11.08 | 51 | 664492 | 788 | 46020731 |
Weight increased | 34.97 | 11.08 | 1949 | 662594 | 162524 | 45858995 |
Joint space narrowing | 34.95 | 11.08 | 23 | 664520 | 119 | 46021400 |
Ulcerative keratitis | 34.95 | 11.08 | 91 | 664452 | 2202 | 46019317 |
Cold sweat | 34.86 | 11.08 | 64 | 664479 | 10881 | 46010638 |
White blood cell count increased | 34.48 | 11.08 | 433 | 664110 | 43786 | 45977733 |
Disability assessment scale score increased | 34.45 | 11.08 | 89 | 664454 | 2143 | 46019376 |
Hepatic cirrhosis | 34.39 | 11.08 | 359 | 664184 | 15373 | 46006146 |
Blood pressure inadequately controlled | 34.36 | 11.08 | 10 | 664533 | 4396 | 46017123 |
Hepatic enzyme abnormal | 34.28 | 11.08 | 136 | 664407 | 4136 | 46017383 |
Mycobacterium chelonae infection | 34.23 | 11.08 | 37 | 664506 | 414 | 46021105 |
Clonus | 34.22 | 11.08 | 8 | 664535 | 4072 | 46017447 |
Non-alcoholic steatohepatitis | 34.19 | 11.08 | 69 | 664474 | 1403 | 46020116 |
Hypotonia | 34.16 | 11.08 | 40 | 664503 | 8189 | 46013330 |
Hepatitis B reactivation | 34.02 | 11.08 | 70 | 664473 | 1444 | 46020075 |
Dry mouth | 34.00 | 11.08 | 563 | 663980 | 54363 | 45967156 |
Bronchial carcinoma | 33.99 | 11.08 | 45 | 664498 | 632 | 46020887 |
Bone swelling | 33.98 | 11.08 | 62 | 664481 | 1166 | 46020353 |
Pancreatitis acute | 33.85 | 11.08 | 211 | 664332 | 24661 | 45996858 |
Hypernatraemia | 33.79 | 11.08 | 25 | 664518 | 6376 | 46015143 |
Disease recurrence | 33.78 | 11.08 | 407 | 664136 | 18064 | 46003455 |
Carpal tunnel syndrome | 33.77 | 11.08 | 360 | 664183 | 15499 | 46006020 |
Colon cancer | 33.76 | 11.08 | 237 | 664306 | 9032 | 46012487 |
Infusion site pruritus | 33.57 | 11.08 | 3 | 664540 | 3135 | 46018384 |
Troponin increased | 33.53 | 11.08 | 37 | 664506 | 7779 | 46013740 |
Pharyngitis streptococcal | 33.52 | 11.08 | 221 | 664322 | 8247 | 46013272 |
Hyperthyroidism | 33.43 | 11.08 | 73 | 664470 | 11638 | 46009881 |
Skin plaque | 33.41 | 11.08 | 168 | 664375 | 5667 | 46015852 |
Pre-existing condition improved | 33.41 | 11.08 | 27 | 664516 | 6585 | 46014934 |
Application site pruritus | 33.40 | 11.08 | 8 | 664535 | 4005 | 46017514 |
Tonsillar ulcer | 33.36 | 11.08 | 29 | 664514 | 242 | 46021277 |
Pulmonary sarcoidosis | 33.22 | 11.08 | 51 | 664492 | 827 | 46020692 |
C-reactive protein decreased | 33.06 | 11.08 | 45 | 664498 | 650 | 46020869 |
Catheter site erythema | 33.03 | 11.08 | 8 | 664535 | 3975 | 46017544 |
Cerebral toxoplasmosis | 33.02 | 11.08 | 46 | 664497 | 680 | 46020839 |
Sacroiliitis | 32.98 | 11.08 | 86 | 664457 | 2083 | 46019436 |
Osteoporotic fracture | 32.97 | 11.08 | 106 | 664437 | 2899 | 46018620 |
Neoplasm recurrence | 32.97 | 11.08 | 91 | 664452 | 2282 | 46019237 |
Nonalcoholic fatty liver disease | 32.95 | 11.08 | 48 | 664495 | 741 | 46020778 |
Foetal growth restriction | 32.95 | 11.08 | 27 | 664516 | 6540 | 46014979 |
Aspiration bone marrow abnormal | 32.94 | 11.08 | 15 | 664528 | 30 | 46021489 |
Small for dates baby | 32.84 | 11.08 | 6 | 664537 | 3631 | 46017888 |
Oliguria | 32.82 | 11.08 | 46 | 664497 | 8713 | 46012806 |
Aphasia | 32.65 | 11.08 | 255 | 664288 | 28312 | 45993207 |
Joint warmth | 32.60 | 11.08 | 62 | 664481 | 1205 | 46020314 |
Electrocardiogram abnormal | 32.57 | 11.08 | 31 | 664512 | 6981 | 46014538 |
Cataract | 32.53 | 11.08 | 862 | 663681 | 44553 | 45976966 |
Angina pectoris | 32.51 | 11.08 | 235 | 664308 | 26540 | 45994979 |
Colitis ischaemic | 32.49 | 11.08 | 59 | 664484 | 10073 | 46011446 |
Limb operation | 32.42 | 11.08 | 113 | 664430 | 3225 | 46018294 |
Leukaemia recurrent | 32.38 | 11.08 | 63 | 664480 | 1246 | 46020273 |
End stage renal disease | 32.37 | 11.08 | 22 | 664521 | 5864 | 46015655 |
Mucosal toxicity | 32.28 | 11.08 | 31 | 664512 | 298 | 46021221 |
Diplopia | 32.26 | 11.08 | 154 | 664389 | 19251 | 46002268 |
Normal newborn | 32.25 | 11.08 | 23 | 664520 | 5978 | 46015541 |
Ileus | 32.20 | 11.08 | 98 | 664445 | 13966 | 46007553 |
Helicobacter infection | 32.20 | 11.08 | 281 | 664262 | 11455 | 46010064 |
Blood prolactin increased | 32.10 | 11.08 | 3 | 664540 | 3024 | 46018495 |
Intestinal obstruction | 32.07 | 11.08 | 228 | 664315 | 25847 | 45995672 |
Underdose | 32.05 | 11.08 | 156 | 664387 | 19402 | 46002117 |
Haemodialysis | 32.01 | 11.08 | 51 | 664492 | 9166 | 46012353 |
Vaginal haemorrhage | 31.93 | 11.08 | 223 | 664320 | 25381 | 45996138 |
Rheumatic fever | 31.85 | 11.08 | 101 | 664442 | 2742 | 46018777 |
Haemolytic anaemia | 31.84 | 11.08 | 57 | 664486 | 9785 | 46011734 |
Product residue present | 31.80 | 11.08 | 8 | 664535 | 3874 | 46017645 |
Ventricular septal defect | 31.74 | 11.08 | 9 | 664534 | 4025 | 46017494 |
Screaming | 31.70 | 11.08 | 4 | 664539 | 3187 | 46018332 |
Breast cancer female | 31.58 | 11.08 | 168 | 664375 | 5795 | 46015724 |
Extrapulmonary tuberculosis | 31.58 | 11.08 | 29 | 664514 | 262 | 46021257 |
Skin reaction | 31.56 | 11.08 | 265 | 664278 | 10681 | 46010838 |
Anti-cyclic citrullinated peptide antibody | 31.49 | 11.08 | 29 | 664514 | 263 | 46021256 |
Bronchospasm | 31.47 | 11.08 | 116 | 664427 | 15591 | 46005928 |
Visual acuity reduced | 31.46 | 11.08 | 185 | 664358 | 21928 | 45999591 |
Skin lesion | 31.45 | 11.08 | 545 | 663998 | 26168 | 45995351 |
Diffuse large B-cell lymphoma stage IV | 31.45 | 11.08 | 26 | 664517 | 201 | 46021318 |
Activated partial thromboplastin time prolonged | 31.36 | 11.08 | 31 | 664512 | 6858 | 46014661 |
Tooth abscess | 31.36 | 11.08 | 296 | 664247 | 12337 | 46009182 |
Aplasia pure red cell | 31.09 | 11.08 | 12 | 664531 | 4413 | 46017106 |
Oxygen consumption increased | 31.09 | 11.08 | 7 | 664536 | 3656 | 46017863 |
Cutaneous leishmaniasis | 31.04 | 11.08 | 18 | 664525 | 71 | 46021448 |
Folliculitis | 30.99 | 11.08 | 172 | 664371 | 6031 | 46015488 |
Respiratory tract infection | 30.92 | 11.08 | 599 | 663944 | 29373 | 45992146 |
Glomerular filtration rate decreased | 30.88 | 11.08 | 76 | 664467 | 11618 | 46009901 |
Sudden death | 30.79 | 11.08 | 55 | 664488 | 9449 | 46012070 |
Prescribed overdose | 30.77 | 11.08 | 64 | 664479 | 10385 | 46011134 |
Tongue neoplasm malignant stage unspecified | 30.76 | 11.08 | 48 | 664495 | 790 | 46020729 |
Increased appetite | 30.75 | 11.08 | 46 | 664497 | 8481 | 46013038 |
Tooth infection | 30.56 | 11.08 | 288 | 664255 | 11998 | 46009521 |
Hypoxic-ischaemic encephalopathy | 30.40 | 11.08 | 10 | 664533 | 4063 | 46017456 |
Choking | 30.38 | 11.08 | 45 | 664498 | 8331 | 46013188 |
Bronchiectasis | 30.38 | 11.08 | 232 | 664311 | 9084 | 46012435 |
Blood calcium increased | 30.31 | 11.08 | 38 | 664505 | 7549 | 46013970 |
Long QT syndrome | 30.27 | 11.08 | 4 | 664539 | 3076 | 46018443 |
Epstein-Barr virus antigen positive | 30.12 | 11.08 | 14 | 664529 | 30 | 46021489 |
Haemorrhoids | 30.07 | 11.08 | 151 | 664392 | 18626 | 46002893 |
Antibody test positive | 30.05 | 11.08 | 83 | 664460 | 2082 | 46019437 |
Arteriosclerosis | 30.05 | 11.08 | 58 | 664485 | 9675 | 46011844 |
Hypertonia | 29.94 | 11.08 | 13 | 664530 | 4453 | 46017066 |
Psychomotor retardation | 29.92 | 11.08 | 5 | 664538 | 3228 | 46018291 |
Personality change | 29.80 | 11.08 | 19 | 664524 | 5239 | 46016280 |
Acute lymphocytic leukaemia | 29.69 | 11.08 | 97 | 664446 | 2676 | 46018843 |
Arachnoiditis | 29.57 | 11.08 | 30 | 664513 | 310 | 46021209 |
Low turnover osteopathy | 29.53 | 11.08 | 12 | 664531 | 4277 | 46017242 |
Ischaemic stroke | 29.41 | 11.08 | 130 | 664413 | 16592 | 46004927 |
Angioimmunoblastic T-cell lymphoma stage IV | 29.40 | 11.08 | 9 | 664534 | 0 | 46021519 |
Cerebral infarction | 29.38 | 11.08 | 203 | 664340 | 23163 | 45998356 |
Bundle branch block right | 29.31 | 11.08 | 16 | 664527 | 4803 | 46016716 |
Hepatic failure | 29.23 | 11.08 | 319 | 664224 | 33097 | 45988422 |
Pain in jaw | 29.08 | 11.08 | 378 | 664165 | 37994 | 45983525 |
Choriocarcinoma | 29.07 | 11.08 | 19 | 664524 | 97 | 46021422 |
Acute pulmonary histoplasmosis | 29.04 | 11.08 | 20 | 664523 | 113 | 46021406 |
Pulmonary arterial pressure increased | 29.03 | 11.08 | 6 | 664537 | 3326 | 46018193 |
Ketoacidosis | 29.02 | 11.08 | 10 | 664533 | 3945 | 46017574 |
Dry eye | 28.95 | 11.08 | 599 | 663944 | 29723 | 45991796 |
Coagulopathy | 28.92 | 11.08 | 150 | 664393 | 18349 | 46003170 |
Incorrect dosage administered | 28.80 | 11.08 | 70 | 664473 | 1621 | 46019898 |
Antinuclear antibody positive | 28.67 | 11.08 | 170 | 664373 | 6110 | 46015409 |
Red cell distribution width decreased | 28.65 | 11.08 | 48 | 664495 | 841 | 46020678 |
Viral vasculitis | 28.61 | 11.08 | 15 | 664528 | 46 | 46021473 |
Bone density decreased | 28.60 | 11.08 | 237 | 664306 | 9515 | 46012004 |
Keratopathy | 28.46 | 11.08 | 28 | 664515 | 278 | 46021241 |
Hypoaesthesia | 28.39 | 11.08 | 1392 | 663151 | 117477 | 45904042 |
Hepatitis B | 28.38 | 11.08 | 116 | 664427 | 3577 | 46017942 |
Joint lock | 28.36 | 11.08 | 79 | 664464 | 1992 | 46019527 |
Proteinuria | 28.32 | 11.08 | 130 | 664413 | 16423 | 46005096 |
Cutaneous T-cell lymphoma | 28.28 | 11.08 | 61 | 664482 | 1302 | 46020217 |
Small intestinal obstruction | 28.27 | 11.08 | 126 | 664417 | 16046 | 46005473 |
Mycobacterial infection | 28.24 | 11.08 | 68 | 664475 | 1565 | 46019954 |
Application site pain | 28.12 | 11.08 | 11 | 664532 | 4012 | 46017507 |
Failure to thrive | 28.09 | 11.08 | 32 | 664511 | 6632 | 46014887 |
Apnoea | 28.04 | 11.08 | 38 | 664505 | 7301 | 46014218 |
Oligohydramnios | 28.01 | 11.08 | 22 | 664521 | 5443 | 46016076 |
Leishmaniasis | 27.93 | 11.08 | 13 | 664530 | 28 | 46021491 |
Blood glucose fluctuation | 27.90 | 11.08 | 12 | 664531 | 4134 | 46017385 |
Post procedural infection | 27.90 | 11.08 | 193 | 664350 | 7320 | 46014199 |
Toxic skin eruption | 27.87 | 11.08 | 87 | 664456 | 12300 | 46009219 |
Injection site irritation | 27.85 | 11.08 | 128 | 664415 | 4159 | 46017360 |
Pericardial effusion | 27.82 | 11.08 | 231 | 664312 | 25312 | 45996207 |
Clostridium difficile infection | 27.80 | 11.08 | 226 | 664317 | 24877 | 45996642 |
Polyuria | 27.75 | 11.08 | 37 | 664506 | 7158 | 46014361 |
Pancreatitis | 27.72 | 11.08 | 445 | 664098 | 43182 | 45978337 |
Incontinence | 27.72 | 11.08 | 62 | 664481 | 9800 | 46011719 |
Encephalopathy | 27.67 | 11.08 | 325 | 664218 | 33264 | 45988255 |
Ophthalmic herpes zoster | 27.63 | 11.08 | 65 | 664478 | 1473 | 46020046 |
Injection site haematoma | 27.61 | 11.08 | 165 | 664378 | 5947 | 46015572 |
Eyelid oedema | 27.59 | 11.08 | 67 | 664476 | 10290 | 46011229 |
Hypophagia | 27.58 | 11.08 | 275 | 664268 | 29031 | 45992488 |
Injection site inflammation | 27.56 | 11.08 | 102 | 664441 | 3000 | 46018519 |
Brain natriuretic peptide increased | 27.47 | 11.08 | 16 | 664527 | 4634 | 46016885 |
Carcinoma in situ of skin | 27.45 | 11.08 | 24 | 664519 | 202 | 46021317 |
Gait disturbance | 27.44 | 11.08 | 2413 | 662130 | 142850 | 45878669 |
Injection site induration | 27.37 | 11.08 | 203 | 664340 | 7876 | 46013643 |
Hepatitis B virus test positive | 27.21 | 11.08 | 23 | 664520 | 184 | 46021335 |
Product label confusion | 27.20 | 11.08 | 29 | 664514 | 319 | 46021200 |
Coma scale abnormal | 27.14 | 11.08 | 19 | 664524 | 4987 | 46016532 |
Therapeutic response unexpected | 27.10 | 11.08 | 122 | 664421 | 15494 | 46006025 |
Gastric disorder | 26.97 | 11.08 | 532 | 664011 | 26173 | 45995346 |
Haematotoxicity | 26.87 | 11.08 | 180 | 664363 | 6753 | 46014766 |
Drug specific antibody | 26.85 | 11.08 | 57 | 664486 | 1203 | 46020316 |
Abortion induced | 26.84 | 11.08 | 67 | 664476 | 10193 | 46011326 |
Meningoencephalitis herpetic | 26.81 | 11.08 | 52 | 664491 | 1026 | 46020493 |
Infective tenosynovitis | 26.38 | 11.08 | 24 | 664519 | 214 | 46021305 |
Eye irritation | 26.38 | 11.08 | 134 | 664409 | 16480 | 46005039 |
Lower respiratory tract infection viral | 26.36 | 11.08 | 35 | 664508 | 493 | 46021026 |
Bicytopenia | 26.36 | 11.08 | 67 | 664476 | 1597 | 46019922 |
Adactyly | 26.35 | 11.08 | 12 | 664531 | 24 | 46021495 |
Erythema | 26.35 | 11.08 | 1715 | 662828 | 141105 | 45880414 |
Coccidioidomycosis | 26.25 | 11.08 | 46 | 664497 | 837 | 46020682 |
Tuberculous pleurisy | 26.23 | 11.08 | 32 | 664511 | 412 | 46021107 |
Hyperventilation | 26.19 | 11.08 | 25 | 664518 | 5622 | 46015897 |
Toe operation | 26.17 | 11.08 | 37 | 664506 | 555 | 46020964 |
Sickle cell anaemia with crisis | 26.16 | 11.08 | 12 | 664531 | 3980 | 46017539 |
Throat tightness | 26.11 | 11.08 | 179 | 664364 | 20460 | 46001059 |
Hepatitis cholestatic | 26.09 | 11.08 | 34 | 664509 | 6643 | 46014876 |
Laryngeal disorder | 26.09 | 11.08 | 45 | 664498 | 808 | 46020711 |
Respiration abnormal | 26.09 | 11.08 | 16 | 664527 | 4505 | 46017014 |
Poor venous access | 26.04 | 11.08 | 205 | 664338 | 8103 | 46013416 |
Squamous cell carcinoma | 26.04 | 11.08 | 196 | 664347 | 7640 | 46013879 |
Left ventricular dysfunction | 26.03 | 11.08 | 68 | 664475 | 10187 | 46011332 |
Migraine | 26.02 | 11.08 | 778 | 663765 | 69248 | 45952271 |
Injection site discolouration | 25.95 | 11.08 | 178 | 664365 | 6732 | 46014787 |
Chondropathy | 25.85 | 11.08 | 74 | 664469 | 1896 | 46019623 |
Dermatitis psoriasiform | 25.77 | 11.08 | 68 | 664475 | 1659 | 46019860 |
Azotaemia | 25.67 | 11.08 | 15 | 664528 | 4336 | 46017183 |
International normalised ratio abnormal | 25.65 | 11.08 | 6 | 664537 | 3053 | 46018466 |
Lung transplant | 25.63 | 11.08 | 5 | 664538 | 2887 | 46018632 |
Urine leukocyte esterase positive | 25.62 | 11.08 | 3 | 664540 | 2532 | 46018987 |
Wheelchair user | 25.54 | 11.08 | 119 | 664424 | 3889 | 46017630 |
Blood bicarbonate decreased | 25.54 | 11.08 | 5 | 664538 | 2880 | 46018639 |
Rectal cancer | 25.47 | 11.08 | 71 | 664472 | 1791 | 46019728 |
Dysphoria | 25.44 | 11.08 | 17 | 664526 | 4572 | 46016947 |
Embolic stroke | 25.35 | 11.08 | 10 | 664533 | 3629 | 46017890 |
Pulse absent | 25.34 | 11.08 | 20 | 664523 | 4936 | 46016583 |
Cartilage atrophy | 25.34 | 11.08 | 21 | 664522 | 163 | 46021356 |
Empyema | 25.25 | 11.08 | 70 | 664473 | 1760 | 46019759 |
Growth failure | 25.19 | 11.08 | 27 | 664516 | 299 | 46021220 |
Rhinitis allergic | 25.17 | 11.08 | 37 | 664506 | 6871 | 46014648 |
Skin papilloma | 25.17 | 11.08 | 122 | 664421 | 4054 | 46017465 |
Spinal pain | 25.16 | 11.08 | 233 | 664310 | 9659 | 46011860 |
Coronary arterial stent insertion | 25.14 | 11.08 | 5 | 664538 | 2848 | 46018671 |
Granuloma | 25.12 | 11.08 | 114 | 664429 | 3684 | 46017835 |
Infected dermal cyst | 25.10 | 11.08 | 32 | 664511 | 432 | 46021087 |
Disease susceptibility | 25.08 | 11.08 | 22 | 664521 | 186 | 46021333 |
Ankle operation | 24.84 | 11.08 | 54 | 664489 | 1159 | 46020360 |
Bunion operation | 24.82 | 11.08 | 43 | 664500 | 775 | 46020744 |
Prescribed underdose | 24.82 | 11.08 | 88 | 664455 | 11965 | 46009554 |
Dermatomyositis | 24.69 | 11.08 | 74 | 664469 | 1947 | 46019572 |
Palmoplantar pustulosis | 24.67 | 11.08 | 28 | 664515 | 332 | 46021187 |
Ganglioneuroma | 24.67 | 11.08 | 19 | 664524 | 131 | 46021388 |
Bundle branch block left | 24.58 | 11.08 | 33 | 664510 | 6366 | 46015153 |
Isosporiasis | 24.53 | 11.08 | 13 | 664530 | 41 | 46021478 |
Ventricular arrhythmia | 24.50 | 11.08 | 9 | 664534 | 3412 | 46018107 |
Maternal exposure during pregnancy | 24.47 | 11.08 | 1201 | 663342 | 101348 | 45920171 |
Renal disorder | 24.46 | 11.08 | 252 | 664291 | 26434 | 45995085 |
Alcohol use | 24.41 | 11.08 | 3 | 664540 | 2439 | 46019080 |
Live birth | 24.36 | 11.08 | 71 | 664472 | 10259 | 46011260 |
Product prescribing error | 24.31 | 11.08 | 176 | 664367 | 19871 | 46001648 |
Varicella | 24.28 | 11.08 | 66 | 664477 | 1640 | 46019879 |
Haemorrhagic stroke | 24.26 | 11.08 | 26 | 664517 | 5540 | 46015979 |
Breast cancer metastatic | 24.25 | 11.08 | 106 | 664437 | 13572 | 46007947 |
Therapy change | 24.23 | 11.08 | 22 | 664521 | 5068 | 46016451 |
Asphyxia | 24.21 | 11.08 | 24 | 664519 | 5302 | 46016217 |
Traumatic lung injury | 24.14 | 11.08 | 59 | 664484 | 1371 | 46020148 |
Performance status decreased | 24.07 | 11.08 | 8 | 664535 | 3229 | 46018290 |
Mean platelet volume decreased | 23.97 | 11.08 | 62 | 664481 | 1494 | 46020025 |
Anaemia megaloblastic | 23.93 | 11.08 | 27 | 664516 | 318 | 46021201 |
Walking aid user | 23.92 | 11.08 | 133 | 664410 | 4667 | 46016852 |
Blood thyroid stimulating hormone increased | 23.86 | 11.08 | 29 | 664514 | 5840 | 46015679 |
Obsessive-compulsive disorder | 23.81 | 11.08 | 8 | 664535 | 3207 | 46018312 |
Drooling | 23.74 | 11.08 | 8 | 664535 | 3201 | 46018318 |
Myocardial ischaemia | 23.72 | 11.08 | 97 | 664446 | 12652 | 46008867 |
Synovial rupture | 23.66 | 11.08 | 20 | 664523 | 160 | 46021359 |
Jaundice cholestatic | 23.63 | 11.08 | 22 | 664521 | 5007 | 46016512 |
Ataxia | 23.48 | 11.08 | 110 | 664433 | 13820 | 46007699 |
Rheumatoid factor | 23.45 | 11.08 | 14 | 664529 | 59 | 46021460 |
Neck mass | 23.41 | 11.08 | 101 | 664442 | 3192 | 46018327 |
Anaplastic large-cell lymphoma | 23.39 | 11.08 | 17 | 664526 | 106 | 46021413 |
Diffuse large B-cell lymphoma stage III | 23.31 | 11.08 | 12 | 664531 | 35 | 46021484 |
Exostosis | 23.29 | 11.08 | 236 | 664307 | 10027 | 46011492 |
Ovarian cancer | 23.27 | 11.08 | 151 | 664392 | 5604 | 46015915 |
Amylase increased | 23.24 | 11.08 | 26 | 664517 | 5433 | 46016086 |
Nail disorder | 23.21 | 11.08 | 192 | 664351 | 7704 | 46013815 |
Salivary gland cancer | 23.16 | 11.08 | 18 | 664525 | 126 | 46021393 |
Chest X-ray abnormal | 23.15 | 11.08 | 110 | 664433 | 3625 | 46017894 |
Systemic lupus erythematosus rash | 23.12 | 11.08 | 54 | 664489 | 1218 | 46020301 |
Mood swings | 23.10 | 11.08 | 136 | 664407 | 16116 | 46005403 |
Nodular melanoma | 23.05 | 11.08 | 13 | 664530 | 48 | 46021471 |
Pulmonary nocardiosis | 23.02 | 11.08 | 16 | 664527 | 92 | 46021427 |
Blood triglycerides increased | 22.97 | 11.08 | 88 | 664455 | 11695 | 46009824 |
Peptic ulcer haemorrhage | 22.95 | 11.08 | 47 | 664496 | 966 | 46020553 |
Engraftment syndrome | 22.72 | 11.08 | 24 | 664519 | 261 | 46021258 |
Middle lobe syndrome | 22.68 | 11.08 | 11 | 664532 | 27 | 46021492 |
Blood chloride decreased | 22.66 | 11.08 | 26 | 664517 | 5371 | 46016148 |
Steroid dependence | 22.62 | 11.08 | 16 | 664527 | 95 | 46021424 |
Mucormycosis | 22.61 | 11.08 | 78 | 664465 | 2214 | 46019305 |
Back pain | 22.54 | 11.08 | 2631 | 661912 | 207408 | 45814111 |
Urticarial vasculitis | 22.52 | 11.08 | 30 | 664513 | 424 | 46021095 |
Clostridium difficile colitis | 22.44 | 11.08 | 163 | 664380 | 18390 | 46003129 |
Catheterisation cardiac | 22.42 | 11.08 | 15 | 664528 | 4032 | 46017487 |
Pelvic pain | 22.39 | 11.08 | 87 | 664456 | 11515 | 46010004 |
Cystitis haemorrhagic | 22.37 | 11.08 | 105 | 664438 | 3442 | 46018077 |
Hepatitis | 22.37 | 11.08 | 609 | 663934 | 31606 | 45989913 |
Bone tuberculosis | 22.36 | 11.08 | 20 | 664523 | 174 | 46021345 |
Restless legs syndrome | 22.29 | 11.08 | 133 | 664410 | 15710 | 46005809 |
Anaphylactic shock | 22.24 | 11.08 | 183 | 664360 | 20091 | 46001428 |
Immune thrombocytopenia | 22.20 | 11.08 | 53 | 664490 | 8188 | 46013331 |
Biliary dyskinesia | 22.17 | 11.08 | 6 | 664537 | 2767 | 46018752 |
Malignant melanoma in situ | 22.15 | 11.08 | 41 | 664502 | 780 | 46020739 |
Feeling hot | 22.10 | 11.08 | 393 | 664150 | 37535 | 45983984 |
Granulomatosis with polyangiitis | 22.03 | 11.08 | 66 | 664477 | 1736 | 46019783 |
Tendon disorder | 22.03 | 11.08 | 134 | 664409 | 4861 | 46016658 |
Tearfulness | 22.02 | 11.08 | 16 | 664527 | 4119 | 46017400 |
Blood phosphorus decreased | 22.02 | 11.08 | 14 | 664529 | 3866 | 46017653 |
Taste disorder | 21.89 | 11.08 | 31 | 664512 | 5847 | 46015672 |
Myelitis transverse | 21.83 | 11.08 | 47 | 664496 | 1002 | 46020517 |
Colitis microscopic | 21.79 | 11.08 | 164 | 664379 | 6392 | 46015127 |
Intervertebral disc space narrowing | 21.78 | 11.08 | 42 | 664501 | 825 | 46020694 |
Application site rash | 21.78 | 11.08 | 5 | 664538 | 2577 | 46018942 |
Pruritus allergic | 21.76 | 11.08 | 47 | 664496 | 1004 | 46020515 |
Blood albumin decreased | 21.74 | 11.08 | 111 | 664432 | 13634 | 46007885 |
Red blood cell sedimentation rate | 21.73 | 11.08 | 65 | 664478 | 1708 | 46019811 |
Anaemia macrocytic | 21.73 | 11.08 | 85 | 664458 | 2568 | 46018951 |
Hair follicle tumour benign | 21.71 | 11.08 | 27 | 664516 | 355 | 46021164 |
Cardiac murmur | 21.70 | 11.08 | 86 | 664457 | 11318 | 46010201 |
Hallucinations, mixed | 21.69 | 11.08 | 14 | 664529 | 3835 | 46017684 |
Borrelia infection | 21.65 | 11.08 | 17 | 664526 | 121 | 46021398 |
Malnutrition | 21.63 | 11.08 | 114 | 664429 | 13889 | 46007630 |
Haemolysis | 21.55 | 11.08 | 33 | 664510 | 6026 | 46015493 |
Alcoholism | 21.51 | 11.08 | 3 | 664540 | 2215 | 46019304 |
Device occlusion | 21.51 | 11.08 | 32 | 664511 | 5913 | 46015606 |
Legionella infection | 21.48 | 11.08 | 28 | 664515 | 387 | 46021132 |
Hyperlactacidaemia | 21.47 | 11.08 | 3 | 664540 | 2212 | 46019307 |
Myocarditis | 21.47 | 11.08 | 49 | 664494 | 7690 | 46013829 |
Bedridden | 21.45 | 11.08 | 212 | 664331 | 8947 | 46012572 |
Therapeutic product effect delayed | 21.42 | 11.08 | 68 | 664475 | 1847 | 46019672 |
Acquired claw toe | 21.42 | 11.08 | 20 | 664523 | 185 | 46021334 |
JC virus infection | 21.39 | 11.08 | 62 | 664481 | 1600 | 46019919 |
Adjustment disorder with depressed mood | 21.38 | 11.08 | 49 | 664494 | 1091 | 46020428 |
Therapeutic response shortened | 21.38 | 11.08 | 137 | 664406 | 5062 | 46016457 |
Decreased immune responsiveness | 21.35 | 11.08 | 105 | 664438 | 3510 | 46018009 |
Diverticular perforation | 21.30 | 11.08 | 99 | 664444 | 3232 | 46018287 |
Lymphadenopathy | 21.29 | 11.08 | 626 | 663917 | 32862 | 45988657 |
Myelodysplastic syndrome | 21.27 | 11.08 | 328 | 664215 | 15383 | 46006136 |
Mass excision | 21.23 | 11.08 | 23 | 664520 | 258 | 46021261 |
Catheter site pain | 21.23 | 11.08 | 14 | 664529 | 3792 | 46017727 |
Acute graft versus host disease in liver | 21.22 | 11.08 | 35 | 664508 | 605 | 46020914 |
Overlap syndrome | 21.22 | 11.08 | 34 | 664509 | 573 | 46020946 |
Hepatosplenomegaly | 21.21 | 11.08 | 79 | 664464 | 2331 | 46019188 |
Pharyngeal ulceration | 21.15 | 11.08 | 32 | 664511 | 512 | 46021007 |
Post-traumatic stress disorder | 21.12 | 11.08 | 16 | 664527 | 4032 | 46017487 |
Thrombophlebitis superficial | 21.11 | 11.08 | 24 | 664519 | 4979 | 46016540 |
Foot fracture | 21.10 | 11.08 | 394 | 664149 | 19188 | 46002331 |
Immunodeficiency | 21.08 | 11.08 | 282 | 664261 | 12824 | 46008695 |
Injection site hypersensitivity | 21.07 | 11.08 | 58 | 664485 | 1452 | 46020067 |
Acute pulmonary oedema | 21.06 | 11.08 | 51 | 664492 | 7840 | 46013679 |
Cervix carcinoma stage 0 | 21.01 | 11.08 | 25 | 664518 | 313 | 46021206 |
Hypermobility syndrome | 21.01 | 11.08 | 36 | 664507 | 643 | 46020876 |
Apathy | 21.00 | 11.08 | 45 | 664498 | 7223 | 46014296 |
Epstein-Barr virus test positive | 20.98 | 11.08 | 33 | 664510 | 547 | 46020972 |
Infusion site haemorrhage | 20.95 | 11.08 | 3 | 664540 | 2171 | 46019348 |
Cardiac failure acute | 20.94 | 11.08 | 53 | 664490 | 8025 | 46013494 |
Vascular device infection | 20.92 | 11.08 | 12 | 664531 | 3505 | 46018014 |
Malignant neoplasm of conjunctiva | 20.92 | 11.08 | 11 | 664532 | 34 | 46021485 |
Blood lactic acid increased | 20.91 | 11.08 | 30 | 664513 | 5627 | 46015892 |
Alanine aminotransferase increased | 20.88 | 11.08 | 1037 | 663506 | 87414 | 45934105 |
Eosinophil count increased | 20.86 | 11.08 | 51 | 664492 | 7815 | 46013704 |
Acute myeloid leukaemia | 20.82 | 11.08 | 328 | 664215 | 15450 | 46006069 |
Hypovolaemic shock | 20.66 | 11.08 | 26 | 664517 | 5157 | 46016362 |
Bursitis | 20.62 | 11.08 | 397 | 664146 | 19445 | 46002074 |
Mesenteritis | 20.61 | 11.08 | 17 | 664526 | 131 | 46021388 |
Rash macular | 20.60 | 11.08 | 175 | 664368 | 19085 | 46002434 |
Fear-related avoidance of activities | 20.58 | 11.08 | 15 | 664528 | 94 | 46021425 |
Cyst | 20.57 | 11.08 | 263 | 664280 | 11837 | 46009682 |
Diffuse large B-cell lymphoma stage II | 20.57 | 11.08 | 12 | 664531 | 48 | 46021471 |
Nausea | 20.46 | 11.08 | 9164 | 655379 | 678290 | 45343229 |
Infiltration anaesthesia | 20.41 | 11.08 | 17 | 664526 | 133 | 46021386 |
Tendon rupture | 20.37 | 11.08 | 184 | 664359 | 7575 | 46013944 |
Prosthesis user | 20.34 | 11.08 | 14 | 664529 | 79 | 46021440 |
Purpura | 20.31 | 11.08 | 73 | 664470 | 9885 | 46011634 |
Oesophageal carcinoma | 20.29 | 11.08 | 40 | 664503 | 799 | 46020720 |
Secondary immunodeficiency | 20.28 | 11.08 | 44 | 664499 | 943 | 46020576 |
Maternal exposure before pregnancy | 20.26 | 11.08 | 121 | 664422 | 4360 | 46017159 |
Glioma | 20.25 | 11.08 | 23 | 664520 | 273 | 46021246 |
Malignant peritoneal neoplasm | 20.25 | 11.08 | 36 | 664507 | 663 | 46020856 |
Abscess sweat gland | 20.23 | 11.08 | 8 | 664535 | 9 | 46021510 |
Cytomegalovirus infection | 20.23 | 11.08 | 367 | 664176 | 17777 | 46003742 |
Laryngitis fungal | 20.21 | 11.08 | 17 | 664526 | 135 | 46021384 |
Cancer pain | 20.16 | 11.08 | 5 | 664538 | 2445 | 46019074 |
Thirst | 20.11 | 11.08 | 84 | 664459 | 10892 | 46010627 |
Alcohol interaction | 20.10 | 11.08 | 5 | 664538 | 2440 | 46019079 |
Dermatitis acneiform | 20.09 | 11.08 | 17 | 664526 | 4053 | 46017466 |
Subdural abscess | 19.96 | 11.08 | 10 | 664533 | 27 | 46021492 |
Ocular sarcoidosis | 19.96 | 11.08 | 10 | 664533 | 27 | 46021492 |
Erythema induratum | 19.96 | 11.08 | 10 | 664533 | 27 | 46021492 |
Abdominal wall haematoma | 19.94 | 11.08 | 8 | 664535 | 2873 | 46018646 |
Hypokinesia | 19.92 | 11.08 | 88 | 664455 | 11234 | 46010285 |
Sinus node dysfunction | 19.87 | 11.08 | 19 | 664524 | 4270 | 46017249 |
Erythrodermic psoriasis | 19.85 | 11.08 | 41 | 664502 | 848 | 46020671 |
Catheter site infection | 19.84 | 11.08 | 23 | 664520 | 4730 | 46016789 |
Plasmablastic lymphoma | 19.84 | 11.08 | 21 | 664522 | 229 | 46021290 |
Galactorrhoea | 19.82 | 11.08 | 15 | 664528 | 3782 | 46017737 |
Post procedural haemorrhage | 19.81 | 11.08 | 48 | 664495 | 7378 | 46014141 |
Emotional disorder | 19.79 | 11.08 | 99 | 664444 | 12225 | 46009294 |
Swollen joint count increased | 19.74 | 11.08 | 77 | 664466 | 2323 | 46019196 |
Enterovirus test positive | 19.73 | 11.08 | 16 | 664527 | 120 | 46021399 |
Major depression | 19.68 | 11.08 | 41 | 664502 | 6649 | 46014870 |
Tongue neoplasm | 19.63 | 11.08 | 11 | 664532 | 40 | 46021479 |
Oropharyngeal discolouration | 19.60 | 11.08 | 6 | 664537 | 0 | 46021519 |
Arthritis viral | 19.60 | 11.08 | 6 | 664537 | 0 | 46021519 |
Osteophyte fracture | 19.60 | 11.08 | 6 | 664537 | 0 | 46021519 |
Electrocardiogram T wave inversion | 19.52 | 11.08 | 13 | 664530 | 3503 | 46018016 |
Hypersomnia | 19.48 | 11.08 | 134 | 664409 | 15305 | 46006214 |
Cardioactive drug level increased | 19.47 | 11.08 | 3 | 664540 | 2056 | 46019463 |
Myelitis | 19.47 | 11.08 | 48 | 664495 | 1122 | 46020397 |
Gastric cancer | 19.43 | 11.08 | 88 | 664455 | 2841 | 46018678 |
Eczema herpeticum | 19.43 | 11.08 | 14 | 664529 | 86 | 46021433 |
Human rhinovirus test positive | 19.42 | 11.08 | 16 | 664527 | 123 | 46021396 |
Hypoventilation | 19.29 | 11.08 | 18 | 664525 | 4092 | 46017427 |
Inadequate analgesia | 19.28 | 11.08 | 8 | 664535 | 2816 | 46018703 |
Blood thyroid stimulating hormone decreased | 19.28 | 11.08 | 17 | 664526 | 3972 | 46017547 |
Hypergammaglobulinaemia benign monoclonal | 19.28 | 11.08 | 34 | 664509 | 622 | 46020897 |
Squamous cell carcinoma of the oral cavity | 19.27 | 11.08 | 23 | 664520 | 289 | 46021230 |
Angina unstable | 19.20 | 11.08 | 50 | 664493 | 7498 | 46014021 |
Anal abscess | 19.17 | 11.08 | 101 | 664442 | 3471 | 46018048 |
Eye movement disorder | 19.15 | 11.08 | 24 | 664519 | 4769 | 46016750 |
Discomfort | 19.15 | 11.08 | 830 | 663713 | 45840 | 45975679 |
Knee deformity | 19.11 | 11.08 | 38 | 664505 | 764 | 46020755 |
Logorrhoea | 19.06 | 11.08 | 5 | 664538 | 2354 | 46019165 |
Chronic recurrent multifocal osteomyelitis | 19.04 | 11.08 | 11 | 664532 | 43 | 46021476 |
Dermatitis contact | 19.03 | 11.08 | 56 | 664487 | 8067 | 46013452 |
Thyroid cancer | 19.02 | 11.08 | 107 | 664436 | 3771 | 46017748 |
Lip and/or oral cavity cancer | 19.00 | 11.08 | 22 | 664521 | 267 | 46021252 |
Hyperthermia | 18.95 | 11.08 | 55 | 664488 | 7959 | 46013560 |
Euglycaemic diabetic ketoacidosis | 18.92 | 11.08 | 3 | 664540 | 2013 | 46019506 |
Cutaneous sarcoidosis | 18.88 | 11.08 | 24 | 664519 | 323 | 46021196 |
Sensory disturbance | 18.88 | 11.08 | 100 | 664443 | 12167 | 46009352 |
Lyme disease | 18.78 | 11.08 | 75 | 664468 | 2288 | 46019231 |
Refusal of treatment by patient | 18.77 | 11.08 | 30 | 664513 | 5385 | 46016134 |
Subdural haemorrhage | 18.71 | 11.08 | 9 | 664534 | 2903 | 46018616 |
Blood pH decreased | 18.67 | 11.08 | 7 | 664536 | 2620 | 46018899 |
Mycobacterium avium complex infection | 18.66 | 11.08 | 81 | 664462 | 2567 | 46018952 |
Incoherent | 18.66 | 11.08 | 22 | 664521 | 4490 | 46017029 |
Back injury | 18.62 | 11.08 | 165 | 664378 | 6756 | 46014763 |
Decubitus ulcer | 18.61 | 11.08 | 75 | 664468 | 9823 | 46011696 |
Cardiomyopathy | 18.59 | 11.08 | 143 | 664400 | 15930 | 46005589 |
Accidental overdose | 18.59 | 11.08 | 189 | 664354 | 19877 | 46001642 |
Lichen myxoedematosus | 18.58 | 11.08 | 9 | 664534 | 22 | 46021497 |
Stress at work | 18.57 | 11.08 | 43 | 664500 | 964 | 46020555 |
Q fever | 18.55 | 11.08 | 12 | 664531 | 60 | 46021459 |
Accidental exposure to product | 18.54 | 11.08 | 201 | 664342 | 20880 | 46000639 |
Squamous cell carcinoma of the cervix | 18.52 | 11.08 | 22 | 664521 | 275 | 46021244 |
Feeling jittery | 18.51 | 11.08 | 87 | 664456 | 10921 | 46010598 |
Listeriosis | 18.44 | 11.08 | 47 | 664496 | 1122 | 46020397 |
Scleroderma renal crisis | 18.44 | 11.08 | 21 | 664522 | 250 | 46021269 |
Catheter site discharge | 18.36 | 11.08 | 3 | 664540 | 1969 | 46019550 |
Self-injurious ideation | 18.34 | 11.08 | 5 | 664538 | 2295 | 46019224 |
Rheumatoid vasculitis | 18.34 | 11.08 | 24 | 664519 | 333 | 46021186 |
Oropharyngeal cancer | 18.33 | 11.08 | 10 | 664533 | 34 | 46021485 |
Nocturia | 18.33 | 11.08 | 47 | 664496 | 7085 | 46014434 |
Varicella zoster pneumonia | 18.31 | 11.08 | 9 | 664534 | 23 | 46021496 |
Gastritis | 18.24 | 11.08 | 362 | 664181 | 34016 | 45987503 |
Cytomegalovirus chorioretinitis | 18.24 | 11.08 | 55 | 664488 | 1452 | 46020067 |
Exercise tolerance decreased | 18.20 | 11.08 | 23 | 664520 | 4554 | 46016965 |
Nephrolithiasis | 18.15 | 11.08 | 607 | 663936 | 32444 | 45989075 |
Metatarsalgia | 18.12 | 11.08 | 18 | 664525 | 181 | 46021338 |
Hepatic function abnormal | 18.10 | 11.08 | 363 | 664180 | 34058 | 45987461 |
Labelled drug-drug interaction medication error | 18.10 | 11.08 | 67 | 664476 | 8994 | 46012525 |
Eructation | 18.04 | 11.08 | 49 | 664494 | 7246 | 46014273 |
Oesophagitis | 17.96 | 11.08 | 117 | 664426 | 13534 | 46007985 |
Lacrimation increased | 17.93 | 11.08 | 142 | 664401 | 15719 | 46005800 |
Social avoidant behaviour | 17.90 | 11.08 | 9 | 664534 | 2830 | 46018689 |
Pharyngeal abscess | 17.89 | 11.08 | 19 | 664524 | 208 | 46021311 |
Pleural fibrosis | 17.86 | 11.08 | 99 | 664444 | 3470 | 46018049 |
Maculopathy | 17.83 | 11.08 | 57 | 664486 | 1554 | 46019965 |
Extrasystoles | 17.82 | 11.08 | 26 | 664517 | 4843 | 46016676 |
Malignant neoplasm of ampulla of Vater | 17.79 | 11.08 | 9 | 664534 | 25 | 46021494 |
Haematochezia | 17.79 | 11.08 | 402 | 664141 | 37091 | 45984428 |
Lung cancer metastatic | 17.78 | 11.08 | 76 | 664467 | 2392 | 46019127 |
Blood sodium increased | 17.77 | 11.08 | 7 | 664536 | 2542 | 46018977 |
Pyomyositis | 17.72 | 11.08 | 24 | 664519 | 345 | 46021174 |
Chemotherapeutic drug level above therapeutic | 17.71 | 11.08 | 10 | 664533 | 37 | 46021482 |
Tachyarrhythmia | 17.68 | 11.08 | 24 | 664519 | 4608 | 46016911 |
Amenorrhoea | 17.62 | 11.08 | 66 | 664477 | 8829 | 46012690 |
Abdominal pain upper | 17.57 | 11.08 | 1805 | 662738 | 143500 | 45878019 |
Electrocardiogram ST segment elevation | 17.56 | 11.08 | 16 | 664527 | 3679 | 46017840 |
Cryptococcosis | 17.53 | 11.08 | 38 | 664505 | 814 | 46020705 |
Spinal disorder | 17.49 | 11.08 | 183 | 664360 | 7841 | 46013678 |
Influenza | 17.48 | 11.08 | 1487 | 663056 | 87783 | 45933736 |
Device leakage | 17.42 | 11.08 | 31 | 664512 | 5334 | 46016185 |
Cervical dysplasia | 17.36 | 11.08 | 86 | 664457 | 2883 | 46018636 |
Road traffic accident | 17.36 | 11.08 | 235 | 664308 | 23456 | 45998063 |
Gestational trophoblastic tumour | 17.33 | 11.08 | 10 | 664533 | 39 | 46021480 |
Guttate psoriasis | 17.32 | 11.08 | 24 | 664519 | 353 | 46021166 |
Muscle haemorrhage | 17.32 | 11.08 | 13 | 664530 | 3291 | 46018228 |
Ocular lymphoma | 17.31 | 11.08 | 11 | 664532 | 53 | 46021466 |
Tonsil cancer | 17.31 | 11.08 | 18 | 664525 | 192 | 46021327 |
Brachiocephalic artery stenosis | 17.31 | 11.08 | 9 | 664534 | 27 | 46021492 |
Heart rate irregular | 17.27 | 11.08 | 175 | 664368 | 18416 | 46003103 |
Mucosal disorder | 17.25 | 11.08 | 63 | 664480 | 1841 | 46019678 |
Bursitis infective | 17.22 | 11.08 | 46 | 664497 | 1131 | 46020388 |
Intervertebral disc protrusion | 17.21 | 11.08 | 396 | 664147 | 20009 | 46001510 |
Eye pruritus | 17.21 | 11.08 | 99 | 664444 | 11799 | 46009720 |
Urticaria | 17.19 | 11.08 | 1444 | 663099 | 116448 | 45905071 |
Bipolar disorder | 17.16 | 11.08 | 49 | 664494 | 7128 | 46014391 |
Skin burning sensation | 17.11 | 11.08 | 86 | 664457 | 10606 | 46010913 |
Abdominal pain lower | 17.04 | 11.08 | 206 | 664337 | 20975 | 46000544 |
Metastases to central nervous system | 16.97 | 11.08 | 92 | 664451 | 11129 | 46010390 |
Rash erythematous | 16.96 | 11.08 | 366 | 664177 | 33984 | 45987535 |
Stress | 16.96 | 11.08 | 897 | 663646 | 50654 | 45970865 |
Injection site discomfort | 16.89 | 11.08 | 97 | 664446 | 3445 | 46018074 |
Gastrointestinal inflammation | 16.87 | 11.08 | 112 | 664431 | 4189 | 46017330 |
Personality disorder | 16.84 | 11.08 | 12 | 664531 | 3121 | 46018398 |
Carbon dioxide decreased | 16.83 | 11.08 | 3 | 664540 | 1848 | 46019671 |
Episcleritis | 16.82 | 11.08 | 35 | 664508 | 728 | 46020791 |
Laryngospasm | 16.81 | 11.08 | 10 | 664533 | 2863 | 46018656 |
Libido decreased | 16.81 | 11.08 | 8 | 664535 | 2597 | 46018922 |
Premature rupture of membranes | 16.80 | 11.08 | 23 | 664520 | 4400 | 46017119 |
Disseminated varicella zoster virus infection | 16.79 | 11.08 | 34 | 664509 | 693 | 46020826 |
Exposure to toxic agent | 16.79 | 11.08 | 4 | 664539 | 2010 | 46019509 |
Keratitis | 16.77 | 11.08 | 75 | 664468 | 2408 | 46019111 |
Growth retardation | 16.77 | 11.08 | 40 | 664503 | 915 | 46020604 |
Sleep disorder due to general medical condition, insomnia type | 16.72 | 11.08 | 130 | 664413 | 5119 | 46016400 |
Exposure to communicable disease | 16.70 | 11.08 | 28 | 664515 | 491 | 46021028 |
Bradyarrhythmia | 16.69 | 11.08 | 4 | 664539 | 2002 | 46019517 |
Cholesteatoma | 16.66 | 11.08 | 14 | 664529 | 111 | 46021408 |
Intervertebral discitis | 16.63 | 11.08 | 76 | 664467 | 2463 | 46019056 |
Myeloid leukaemia | 16.61 | 11.08 | 22 | 664521 | 309 | 46021210 |
Double stranded DNULL antibody positive | 16.61 | 11.08 | 18 | 664525 | 202 | 46021317 |
Respiratory rate increased | 16.61 | 11.08 | 95 | 664448 | 11338 | 46010181 |
Renal cancer | 16.61 | 11.08 | 89 | 664454 | 3079 | 46018440 |
Retinitis | 16.59 | 11.08 | 24 | 664519 | 368 | 46021151 |
Chronic villitis of unknown etiology | 16.59 | 11.08 | 6 | 664537 | 4 | 46021515 |
Adverse event | 16.59 | 11.08 | 619 | 663924 | 33565 | 45987954 |
Metastatic bronchial carcinoma | 16.56 | 11.08 | 14 | 664529 | 112 | 46021407 |
Thrombosis in device | 16.56 | 11.08 | 11 | 664532 | 2968 | 46018551 |
Inhibitory drug interaction | 16.56 | 11.08 | 4 | 664539 | 1991 | 46019528 |
Cutaneous tuberculosis | 16.55 | 11.08 | 15 | 664528 | 133 | 46021386 |
Infusion site extravasation | 16.51 | 11.08 | 31 | 664512 | 5225 | 46016294 |
Weight decreased | 16.48 | 11.08 | 2693 | 661850 | 208156 | 45813363 |
Hyperuricaemia | 16.48 | 11.08 | 26 | 664517 | 4691 | 46016828 |
Psychiatric symptom | 16.47 | 11.08 | 24 | 664519 | 4473 | 46017046 |
Catheter site haemorrhage | 16.47 | 11.08 | 9 | 664534 | 2700 | 46018819 |
T-cell lymphoma | 16.45 | 11.08 | 31 | 664512 | 598 | 46020921 |
Urine ketone body present | 16.45 | 11.08 | 5 | 664538 | 2137 | 46019382 |
Incorrect dose administered | 16.44 | 11.08 | 508 | 664035 | 45042 | 45976477 |
Cardiac pacemaker insertion | 16.44 | 11.08 | 17 | 664526 | 3682 | 46017837 |
Application site irritation | 16.43 | 11.08 | 3 | 664540 | 1816 | 46019703 |
Angle closure glaucoma | 16.42 | 11.08 | 5 | 664538 | 2134 | 46019385 |
Wernicke's encephalopathy | 16.41 | 11.08 | 9 | 664534 | 31 | 46021488 |
Lung squamous cell carcinoma stage I | 16.41 | 11.08 | 7 | 664536 | 11 | 46021508 |
Bone density abnormal | 16.41 | 11.08 | 87 | 664456 | 2997 | 46018522 |
Large granular lymphocytosis | 16.41 | 11.08 | 16 | 664527 | 157 | 46021362 |
Torus fracture | 16.40 | 11.08 | 13 | 664530 | 94 | 46021425 |
Leukodystrophy | 16.39 | 11.08 | 8 | 664535 | 20 | 46021499 |
Extra dose administered | 16.39 | 11.08 | 26 | 664517 | 4681 | 46016838 |
Ammonia increased | 16.39 | 11.08 | 23 | 664520 | 4354 | 46017165 |
Exposed bone in jaw | 16.33 | 11.08 | 13 | 664530 | 3195 | 46018324 |
Respiratory tract ulceration | 16.33 | 11.08 | 5 | 664538 | 0 | 46021519 |
Angioimmunoblastic T-cell lymphoma stage III | 16.33 | 11.08 | 5 | 664538 | 0 | 46021519 |
Pertussis | 16.30 | 11.08 | 30 | 664513 | 568 | 46020951 |
Electrocardiogram ST segment depression | 16.29 | 11.08 | 9 | 664534 | 2684 | 46018835 |
Pleuropericarditis | 16.28 | 11.08 | 18 | 664525 | 207 | 46021312 |
Rales | 16.26 | 11.08 | 76 | 664467 | 9555 | 46011964 |
Snoring | 16.24 | 11.08 | 15 | 664528 | 3427 | 46018092 |
Thrombotic thrombocytopenic purpura | 16.24 | 11.08 | 19 | 664524 | 3891 | 46017628 |
Quadriplegia | 16.18 | 11.08 | 58 | 664485 | 1679 | 46019840 |
Product taste abnormal | 16.17 | 11.08 | 4 | 664539 | 1959 | 46019560 |
Duodenal ulcer haemorrhage | 16.16 | 11.08 | 7 | 664536 | 2401 | 46019118 |
Plasma cell myeloma recurrent | 16.15 | 11.08 | 7 | 664536 | 2400 | 46019119 |
Drug-device interaction | 16.13 | 11.08 | 11 | 664532 | 61 | 46021458 |
Coronary artery occlusion | 16.12 | 11.08 | 60 | 664483 | 8042 | 46013477 |
Idiopathic pneumonia syndrome | 16.08 | 11.08 | 23 | 664520 | 349 | 46021170 |
Portal tract inflammation | 16.05 | 11.08 | 7 | 664536 | 12 | 46021507 |
Chronic graft versus host disease in liver | 15.95 | 11.08 | 16 | 664527 | 163 | 46021356 |
Peripheral coldness | 15.92 | 11.08 | 79 | 664464 | 9776 | 46011743 |
Insurance issue | 15.91 | 11.08 | 3 | 664540 | 1775 | 46019744 |
Stoma site discharge | 15.89 | 11.08 | 4 | 664539 | 1936 | 46019583 |
Nystagmus | 15.88 | 11.08 | 36 | 664507 | 5663 | 46015856 |
Ecchymosis | 15.84 | 11.08 | 87 | 664456 | 10489 | 46011030 |
Duodenal ulcer perforation | 15.84 | 11.08 | 188 | 664355 | 8314 | 46013205 |
Cholestatic liver injury | 15.83 | 11.08 | 5 | 664538 | 2085 | 46019434 |
Soft tissue disorder | 15.82 | 11.08 | 108 | 664435 | 4078 | 46017441 |
Infection reactivation | 15.78 | 11.08 | 35 | 664508 | 762 | 46020757 |
Rib fracture | 15.77 | 11.08 | 183 | 664360 | 18771 | 46002748 |
Cardiovascular disorder | 15.76 | 11.08 | 105 | 664438 | 12082 | 46009437 |
Meningitis tuberculous | 15.73 | 11.08 | 29 | 664514 | 550 | 46020969 |
Perineal infection | 15.72 | 11.08 | 14 | 664529 | 121 | 46021398 |
Endometrial adenocarcinoma | 15.71 | 11.08 | 44 | 664499 | 1113 | 46020406 |
International normalised ratio decreased | 15.71 | 11.08 | 25 | 664518 | 4495 | 46017024 |
Femoroacetabular impingement | 15.70 | 11.08 | 7 | 664536 | 13 | 46021506 |
Cytomegalovirus enteritis | 15.67 | 11.08 | 17 | 664526 | 191 | 46021328 |
Respiratory tract congestion | 15.60 | 11.08 | 262 | 664281 | 12502 | 46009017 |
Fracture | 15.59 | 11.08 | 325 | 664218 | 16146 | 46005373 |
Infusion site reaction | 15.58 | 11.08 | 58 | 664485 | 1711 | 46019808 |
Metastasis | 15.56 | 11.08 | 110 | 664433 | 4202 | 46017317 |
Herpes virus infection | 15.55 | 11.08 | 119 | 664424 | 4663 | 46016856 |
Ocular toxicity | 15.54 | 11.08 | 26 | 664517 | 455 | 46021064 |
Tendon graft | 15.53 | 11.08 | 6 | 664537 | 6 | 46021513 |
Gallbladder necrosis | 15.53 | 11.08 | 6 | 664537 | 6 | 46021513 |
Wound infection | 15.48 | 11.08 | 220 | 664323 | 10139 | 46011380 |
Electrocardiogram T wave abnormal | 15.46 | 11.08 | 7 | 664536 | 2339 | 46019180 |
Mononeuritis | 15.43 | 11.08 | 9 | 664534 | 36 | 46021483 |
Hyperparathyroidism | 15.42 | 11.08 | 8 | 664535 | 2471 | 46019048 |
Atelectasis | 15.40 | 11.08 | 182 | 664361 | 18608 | 46002911 |
Pulmonary function test decreased | 15.40 | 11.08 | 19 | 664524 | 3801 | 46017718 |
Ischaemic cardiomyopathy | 15.39 | 11.08 | 9 | 664534 | 2601 | 46018918 |
Post procedural inflammation | 15.38 | 11.08 | 8 | 664535 | 24 | 46021495 |
Lower respiratory tract inflammation | 15.38 | 11.08 | 13 | 664530 | 104 | 46021415 |
Nasopharyngeal cancer | 15.37 | 11.08 | 7 | 664536 | 14 | 46021505 |
Rotator cuff syndrome | 15.37 | 11.08 | 241 | 664302 | 11342 | 46010177 |
Medication error | 15.36 | 11.08 | 329 | 664214 | 30582 | 45990937 |
Ventricular hypertrophy | 15.34 | 11.08 | 19 | 664524 | 3795 | 46017724 |
Respiratory rate decreased | 15.34 | 11.08 | 13 | 664530 | 3097 | 46018422 |
Histiocytic sarcoma | 15.34 | 11.08 | 11 | 664532 | 67 | 46021452 |
Blood pressure diastolic decreased | 15.34 | 11.08 | 286 | 664257 | 13925 | 46007594 |
Herpes zoster oticus | 15.33 | 11.08 | 18 | 664525 | 222 | 46021297 |
Pneumocystis jirovecii infection | 15.33 | 11.08 | 46 | 664497 | 1211 | 46020308 |
Sinus arrest | 15.32 | 11.08 | 3 | 664540 | 1728 | 46019791 |
Iris adhesions | 15.30 | 11.08 | 21 | 664522 | 306 | 46021213 |
Protein total decreased | 15.29 | 11.08 | 35 | 664508 | 5488 | 46016031 |
Premature separation of placenta | 15.29 | 11.08 | 3 | 664540 | 1725 | 46019794 |
Eye infection toxoplasmal | 15.26 | 11.08 | 20 | 664523 | 278 | 46021241 |
Tubular breast carcinoma | 15.24 | 11.08 | 9 | 664534 | 37 | 46021482 |
Implant site pain | 15.22 | 11.08 | 6 | 664537 | 2178 | 46019341 |
Arteriosclerosis coronary artery | 15.21 | 11.08 | 62 | 664481 | 8094 | 46013425 |
Chorioretinopathy | 15.19 | 11.08 | 33 | 664510 | 708 | 46020811 |
Fatigue | 15.17 | 11.08 | 8160 | 656383 | 600537 | 45420982 |
Genital infection | 15.16 | 11.08 | 10 | 664533 | 52 | 46021467 |
Diastolic dysfunction | 15.09 | 11.08 | 33 | 664510 | 5259 | 46016260 |
Portal fibrosis | 15.08 | 11.08 | 17 | 664526 | 200 | 46021319 |
Papulopustular rosacea | 15.06 | 11.08 | 7 | 664536 | 15 | 46021504 |
Economic problem | 15.01 | 11.08 | 5 | 664538 | 2015 | 46019504 |
Hypoglycaemic coma | 15.01 | 11.08 | 9 | 664534 | 2565 | 46018954 |
Concomitant disease progression | 14.97 | 11.08 | 6 | 664537 | 2156 | 46019363 |
Left ventricular hypertrophy | 14.95 | 11.08 | 30 | 664513 | 4933 | 46016586 |
Quadrantanopia | 14.93 | 11.08 | 8 | 664535 | 26 | 46021493 |
Communication disorder | 14.91 | 11.08 | 8 | 664535 | 2425 | 46019094 |
Cytomegalovirus viraemia | 14.87 | 11.08 | 112 | 664431 | 4366 | 46017153 |
Haemodynamic instability | 14.86 | 11.08 | 58 | 664485 | 7667 | 46013852 |
Neck deformity | 14.86 | 11.08 | 59 | 664484 | 1795 | 46019724 |
Folate deficiency | 14.85 | 11.08 | 56 | 664487 | 1662 | 46019857 |
Throat cancer | 14.84 | 11.08 | 25 | 664518 | 440 | 46021079 |
Blood pressure diastolic increased | 14.84 | 11.08 | 140 | 664403 | 5834 | 46015685 |
Skin swelling | 14.83 | 11.08 | 63 | 664480 | 1977 | 46019542 |
Gastrointestinal lymphoma | 14.72 | 11.08 | 9 | 664534 | 40 | 46021479 |
Deafness neurosensory | 14.70 | 11.08 | 112 | 664431 | 4382 | 46017137 |
Body height decreased | 14.68 | 11.08 | 79 | 664464 | 9573 | 46011946 |
Chloroma | 14.67 | 11.08 | 16 | 664527 | 181 | 46021338 |
Duodenal ulcer | 14.66 | 11.08 | 53 | 664490 | 7165 | 46014354 |
Anxiety disorder | 14.65 | 11.08 | 17 | 664526 | 3494 | 46018025 |
Follicle centre lymphoma, follicular grade I, II, III | 14.61 | 11.08 | 11 | 664532 | 73 | 46021446 |
Gout | 14.61 | 11.08 | 98 | 664445 | 11258 | 46010261 |
DNULL antibody positive | 14.57 | 11.08 | 21 | 664522 | 321 | 46021198 |
Invasive ductal breast carcinoma | 14.56 | 11.08 | 143 | 664400 | 6025 | 46015494 |
Respiratory tract haemorrhage | 14.54 | 11.08 | 22 | 664521 | 352 | 46021167 |
Inflammatory pain | 14.51 | 11.08 | 30 | 664513 | 621 | 46020898 |
Mean cell volume decreased | 14.50 | 11.08 | 71 | 664472 | 2369 | 46019150 |
Immunisation reaction | 14.48 | 11.08 | 7 | 664536 | 17 | 46021502 |
Herpes simplex | 14.47 | 11.08 | 162 | 664381 | 7061 | 46014458 |
Acute interstitial pneumonitis | 14.45 | 11.08 | 31 | 664512 | 659 | 46020860 |
Central nervous system lesion | 14.45 | 11.08 | 79 | 664464 | 9536 | 46011983 |
Intestinal sepsis | 14.45 | 11.08 | 18 | 664525 | 237 | 46021282 |
Hypertensive crisis | 14.43 | 11.08 | 124 | 664419 | 13491 | 46008028 |
Tension | 14.37 | 11.08 | 12 | 664531 | 2880 | 46018639 |
Pleural thickening | 14.36 | 11.08 | 74 | 664469 | 2521 | 46018998 |
Lip oedema | 14.35 | 11.08 | 16 | 664527 | 3348 | 46018171 |
Anal cancer | 14.30 | 11.08 | 25 | 664518 | 454 | 46021065 |
Mucosal necrosis | 14.29 | 11.08 | 8 | 664535 | 29 | 46021490 |
Root canal infection | 14.28 | 11.08 | 13 | 664530 | 116 | 46021403 |
Osteochondrosis | 14.28 | 11.08 | 38 | 664505 | 932 | 46020587 |
Second primary malignancy | 14.27 | 11.08 | 150 | 664393 | 6434 | 46015085 |
Abscess limb | 14.27 | 11.08 | 107 | 664436 | 4166 | 46017353 |
Corneal oedema | 14.26 | 11.08 | 3 | 664540 | 1643 | 46019876 |
Skin mass | 14.26 | 11.08 | 126 | 664417 | 5154 | 46016365 |
BK virus infection | 14.23 | 11.08 | 79 | 664464 | 2770 | 46018749 |
Psoriasis area severity index increased | 14.22 | 11.08 | 9 | 664534 | 43 | 46021476 |
Akinesia | 14.21 | 11.08 | 4 | 664539 | 1797 | 46019722 |
Tibia fracture | 14.20 | 11.08 | 111 | 664432 | 4378 | 46017141 |
Supraventricular extrasystoles | 14.20 | 11.08 | 23 | 664520 | 4106 | 46017413 |
Fungal infection | 14.19 | 11.08 | 534 | 664009 | 28986 | 45992533 |
Cystic fibrosis | 14.19 | 11.08 | 19 | 664524 | 3669 | 46017850 |
Scarlet fever | 14.15 | 11.08 | 11 | 664532 | 77 | 46021442 |
Oral disorder | 14.15 | 11.08 | 172 | 664371 | 7650 | 46013869 |
Immune system disorder | 14.11 | 11.08 | 175 | 664368 | 7820 | 46013699 |
Cerebral haematoma | 14.11 | 11.08 | 16 | 664527 | 3323 | 46018196 |
Monoclonal gammopathy | 14.10 | 11.08 | 29 | 664514 | 598 | 46020921 |
Septic arthritis staphylococcal | 14.09 | 11.08 | 23 | 664520 | 394 | 46021125 |
Tongue oedema | 14.07 | 11.08 | 22 | 664521 | 3984 | 46017535 |
Renal artery stenosis | 14.05 | 11.08 | 4 | 664539 | 1784 | 46019735 |
Malabsorption | 14.04 | 11.08 | 20 | 664523 | 3763 | 46017756 |
Skin tightness | 14.04 | 11.08 | 21 | 664522 | 3872 | 46017647 |
Fontanelle bulging | 14.02 | 11.08 | 5 | 664538 | 3 | 46021516 |
Food allergy | 14.02 | 11.08 | 51 | 664492 | 6882 | 46014637 |
Extremity contracture | 14.02 | 11.08 | 43 | 664500 | 1146 | 46020373 |
Medial tibial stress syndrome | 14.00 | 11.08 | 12 | 664531 | 98 | 46021421 |
Stress cardiomyopathy | 14.00 | 11.08 | 60 | 664483 | 7724 | 46013795 |
Crying | 13.98 | 11.08 | 214 | 664329 | 20927 | 46000592 |
Waldenstrom's macroglobulinaemia | 13.95 | 11.08 | 7 | 664536 | 19 | 46021500 |
Intervertebral disc compression | 13.93 | 11.08 | 38 | 664505 | 946 | 46020573 |
Small intestinal haemorrhage | 13.91 | 11.08 | 5 | 664538 | 1921 | 46019598 |
Uterine cancer | 13.90 | 11.08 | 91 | 664452 | 3387 | 46018132 |
Bone cyst | 13.89 | 11.08 | 62 | 664481 | 1989 | 46019530 |
Dyspepsia | 13.87 | 11.08 | 815 | 663728 | 67657 | 45953862 |
Meningitis | 13.87 | 11.08 | 141 | 664402 | 5995 | 46015524 |
Pasteurella infection | 13.86 | 11.08 | 6 | 664537 | 10 | 46021509 |
Polymerase chain reaction | 13.86 | 11.08 | 6 | 664537 | 10 | 46021509 |
Lung adenocarcinoma stage III | 13.86 | 11.08 | 6 | 664537 | 10 | 46021509 |
Protein urine present | 13.82 | 11.08 | 33 | 664510 | 5098 | 46016421 |
Electroencephalogram abnormal | 13.78 | 11.08 | 20 | 664523 | 3734 | 46017785 |
Subcutaneous abscess | 13.77 | 11.08 | 121 | 664422 | 4942 | 46016577 |
Congestive hepatopathy | 13.77 | 11.08 | 9 | 664534 | 2449 | 46019070 |
Genital cyst | 13.76 | 11.08 | 9 | 664534 | 46 | 46021473 |
Nephrogenic anaemia | 13.76 | 11.08 | 5 | 664538 | 1908 | 46019611 |
Peripheral T-cell lymphoma unspecified | 13.75 | 11.08 | 17 | 664526 | 222 | 46021297 |
Eye infection | 13.74 | 11.08 | 194 | 664349 | 8929 | 46012590 |
Blood lactate dehydrogenase increased | 13.73 | 11.08 | 207 | 664336 | 20293 | 46001226 |
Oesophageal squamous cell carcinoma | 13.72 | 11.08 | 12 | 664531 | 101 | 46021418 |
Bone disorder | 13.71 | 11.08 | 378 | 664165 | 19655 | 46001864 |
West Nile viral infection | 13.64 | 11.08 | 22 | 664521 | 373 | 46021146 |
Bronchiolitis obliterans syndrome | 13.62 | 11.08 | 11 | 664532 | 82 | 46021437 |
Micturition urgency | 13.61 | 11.08 | 61 | 664482 | 7756 | 46013763 |
Euphoric mood | 13.59 | 11.08 | 25 | 664518 | 4247 | 46017272 |
Multiple-drug resistance | 13.56 | 11.08 | 10 | 664533 | 2555 | 46018964 |
Bursitis infective staphylococcal | 13.53 | 11.08 | 8 | 664535 | 33 | 46021486 |
Anaplastic thyroid cancer | 13.53 | 11.08 | 8 | 664535 | 33 | 46021486 |
Urine abnormality | 13.52 | 11.08 | 38 | 664505 | 5556 | 46015963 |
Hip surgery | 13.51 | 11.08 | 70 | 664473 | 2390 | 46019129 |
Diabetic retinopathy | 13.49 | 11.08 | 8 | 664535 | 2294 | 46019225 |
Cervix carcinoma | 13.48 | 11.08 | 75 | 664468 | 2632 | 46018887 |
Subclavian artery occlusion | 13.46 | 11.08 | 7 | 664536 | 21 | 46021498 |
Combined immunodeficiency | 13.45 | 11.08 | 12 | 664531 | 104 | 46021415 |
Lymphoplasmacytoid lymphoma/immunocytoma | 13.45 | 11.08 | 5 | 664538 | 4 | 46021515 |
Cytomegalovirus gastrointestinal ulcer | 13.45 | 11.08 | 5 | 664538 | 4 | 46021515 |
Impetigo | 13.45 | 11.08 | 37 | 664506 | 926 | 46020593 |
Vaginal cancer | 13.42 | 11.08 | 17 | 664526 | 228 | 46021291 |
Blood urine present | 13.41 | 11.08 | 111 | 664432 | 12171 | 46009348 |
Ovarian epithelial cancer | 13.40 | 11.08 | 20 | 664523 | 316 | 46021203 |
Morphoea | 13.39 | 11.08 | 19 | 664524 | 286 | 46021233 |
Ocular vasculitis | 13.35 | 11.08 | 8 | 664535 | 34 | 46021485 |
Foreign body sensation in eyes | 13.33 | 11.08 | 5 | 664538 | 1871 | 46019648 |
T-cell type acute leukaemia | 13.32 | 11.08 | 10 | 664533 | 66 | 46021453 |
Prosthesis implantation | 13.32 | 11.08 | 10 | 664533 | 66 | 46021453 |
Vasculitic rash | 13.29 | 11.08 | 45 | 664498 | 1265 | 46020254 |
Dyspnoea at rest | 13.29 | 11.08 | 19 | 664524 | 3569 | 46017950 |
Appendicitis | 13.28 | 11.08 | 145 | 664398 | 6281 | 46015238 |
Bursa disorder | 13.28 | 11.08 | 12 | 664531 | 106 | 46021413 |
Bowen's disease | 13.25 | 11.08 | 17 | 664526 | 231 | 46021288 |
Papilloma viral infection | 13.25 | 11.08 | 46 | 664497 | 1310 | 46020209 |
Erythema migrans | 13.23 | 11.08 | 7 | 664536 | 22 | 46021497 |
Effusion | 13.22 | 11.08 | 49 | 664494 | 1442 | 46020077 |
Loose body in joint | 13.22 | 11.08 | 39 | 664504 | 1017 | 46020502 |
Iridocyclitis | 13.20 | 11.08 | 60 | 664483 | 1940 | 46019579 |
Intramedullary rod insertion | 13.20 | 11.08 | 7 | 664536 | 2136 | 46019383 |
Perineal necrosis | 13.19 | 11.08 | 12 | 664531 | 107 | 46021412 |
Joint tuberculosis | 13.19 | 11.08 | 12 | 664531 | 107 | 46021412 |
Metastases to reproductive organ | 13.18 | 11.08 | 6 | 664537 | 12 | 46021507 |
Rash morbilliform | 13.18 | 11.08 | 14 | 664529 | 2995 | 46018524 |
DNULL antibody | 13.18 | 11.08 | 8 | 664535 | 35 | 46021484 |
Joint surgery | 13.17 | 11.08 | 20 | 664523 | 321 | 46021198 |
Pulmonary granuloma | 13.17 | 11.08 | 45 | 664498 | 1271 | 46020248 |
Blood parathyroid hormone increased | 13.17 | 11.08 | 14 | 664529 | 2994 | 46018525 |
N-terminal prohormone brain natriuretic peptide increased | 13.13 | 11.08 | 4 | 664539 | 1707 | 46019812 |
Musculoskeletal chest pain | 13.12 | 11.08 | 180 | 664363 | 17926 | 46003593 |
Clear cell renal cell carcinoma | 13.10 | 11.08 | 38 | 664505 | 981 | 46020538 |
Muscle injury | 13.08 | 11.08 | 116 | 664427 | 4750 | 46016769 |
Ectrodactyly | 13.07 | 11.08 | 4 | 664539 | 0 | 46021519 |
CSF myelin basic protein increased | 13.07 | 11.08 | 4 | 664539 | 0 | 46021519 |
Bursa injury | 13.07 | 11.08 | 4 | 664539 | 0 | 46021519 |
Cutaneous T-cell lymphoma recurrent | 13.07 | 11.08 | 4 | 664539 | 0 | 46021519 |
Leptotrichia infection | 13.07 | 11.08 | 4 | 664539 | 0 | 46021519 |
Bladder papilloma | 13.07 | 11.08 | 4 | 664539 | 0 | 46021519 |
Thrombotic microangiopathy | 13.06 | 11.08 | 178 | 664365 | 8128 | 46013391 |
Breast mass | 13.06 | 11.08 | 141 | 664402 | 6090 | 46015429 |
Pneumonia adenoviral | 13.01 | 11.08 | 7 | 664536 | 23 | 46021496 |
Petit mal epilepsy | 13.00 | 11.08 | 16 | 664527 | 3204 | 46018315 |
Expired product administered | 12.99 | 11.08 | 39 | 664504 | 5583 | 46015936 |
Anovulatory cycle | 12.99 | 11.08 | 13 | 664530 | 132 | 46021387 |
Furuncle | 12.98 | 11.08 | 119 | 664424 | 4919 | 46016600 |
Injection related reaction | 12.90 | 11.08 | 25 | 664518 | 493 | 46021026 |
Tumour marker increased | 12.87 | 11.08 | 19 | 664524 | 3522 | 46017997 |
Tender joint count increased | 12.87 | 11.08 | 6 | 664537 | 13 | 46021506 |
Cutaneous lymphoma | 12.86 | 11.08 | 14 | 664529 | 158 | 46021361 |
Blood chloride increased | 12.85 | 11.08 | 11 | 664532 | 2608 | 46018911 |
Chromosomal deletion | 12.84 | 11.08 | 8 | 664535 | 37 | 46021482 |
Abscess bacterial | 12.84 | 11.08 | 15 | 664528 | 184 | 46021335 |
Pseudomonas test positive | 12.83 | 11.08 | 31 | 664512 | 715 | 46020804 |
Arthritis enteropathic | 12.83 | 11.08 | 16 | 664527 | 211 | 46021308 |
Allergy to vaccine | 12.79 | 11.08 | 14 | 664529 | 159 | 46021360 |
Bloody discharge | 12.79 | 11.08 | 37 | 664506 | 954 | 46020565 |
Serum ferritin decreased | 12.78 | 11.08 | 52 | 664491 | 1600 | 46019919 |
Pemphigoid | 12.78 | 11.08 | 40 | 664503 | 5651 | 46015868 |
Breast pain | 12.78 | 11.08 | 60 | 664483 | 7534 | 46013985 |
Cytomegalovirus infection reactivation | 12.74 | 11.08 | 48 | 664495 | 1424 | 46020095 |
Bone marrow disorder | 12.70 | 11.08 | 55 | 664488 | 1741 | 46019778 |
Transplant dysfunction | 12.70 | 11.08 | 30 | 664513 | 4652 | 46016867 |
Pyoderma gangrenosum | 12.69 | 11.08 | 74 | 664469 | 2643 | 46018876 |
Diffuse alveolar damage | 12.69 | 11.08 | 32 | 664511 | 759 | 46020760 |
Right ventricular dysfunction | 12.69 | 11.08 | 3 | 664540 | 1515 | 46020004 |
Infected seroma | 12.65 | 11.08 | 9 | 664534 | 54 | 46021465 |
Brain oedema | 12.63 | 11.08 | 115 | 664428 | 12363 | 46009156 |
Skin bacterial infection | 12.62 | 11.08 | 17 | 664526 | 243 | 46021276 |
Craniosynostosis | 12.62 | 11.08 | 13 | 664530 | 137 | 46021382 |
Skin neoplasm excision | 12.62 | 11.08 | 27 | 664516 | 573 | 46020946 |
Device failure | 12.61 | 11.08 | 43 | 664500 | 5916 | 46015603 |
Nodal osteoarthritis | 12.61 | 11.08 | 32 | 664511 | 762 | 46020757 |
Larynx irritation | 12.60 | 11.08 | 12 | 664531 | 114 | 46021405 |
Seasonal allergy | 12.60 | 11.08 | 125 | 664418 | 13209 | 46008310 |
Pterygium | 12.60 | 11.08 | 14 | 664529 | 162 | 46021357 |
Enzyme level increased | 12.59 | 11.08 | 15 | 664528 | 188 | 46021331 |
Pneumonia influenzal | 12.57 | 11.08 | 3 | 664540 | 1506 | 46020013 |
Granulomatous lymphadenitis | 12.55 | 11.08 | 13 | 664530 | 138 | 46021381 |
Dysphonia | 12.54 | 11.08 | 434 | 664109 | 37980 | 45983539 |
Hiatus hernia | 12.54 | 11.08 | 184 | 664359 | 18118 | 46003401 |
Stenosis | 12.53 | 11.08 | 33 | 664510 | 804 | 46020715 |
Ocular hyperaemia | 12.53 | 11.08 | 201 | 664342 | 19509 | 46002010 |
Adenocarcinoma of the cervix | 12.53 | 11.08 | 14 | 664529 | 163 | 46021356 |
Generalised anxiety disorder | 12.53 | 11.08 | 4 | 664539 | 1656 | 46019863 |
Lipodystrophy acquired | 12.53 | 11.08 | 3 | 664540 | 1502 | 46020017 |
Brain death | 12.51 | 11.08 | 13 | 664530 | 2810 | 46018709 |
Homicidal ideation | 12.48 | 11.08 | 5 | 664538 | 1797 | 46019722 |
Myxoid liposarcoma | 12.48 | 11.08 | 5 | 664538 | 6 | 46021513 |
Genital herpes | 12.46 | 11.08 | 50 | 664493 | 1529 | 46019990 |
Chronic cutaneous lupus erythematosus | 12.45 | 11.08 | 11 | 664532 | 94 | 46021425 |
Product container issue | 12.44 | 11.08 | 5 | 664538 | 1794 | 46019725 |
Maternal exposure timing unspecified | 12.43 | 11.08 | 3 | 664540 | 1494 | 46020025 |
Breath sounds abnormal | 12.42 | 11.08 | 63 | 664480 | 7752 | 46013767 |
Blood pressure increased | 12.40 | 11.08 | 1596 | 662947 | 125070 | 45896449 |
Vitreous floaters | 12.39 | 11.08 | 34 | 664509 | 5011 | 46016508 |
Decreased interest | 12.37 | 11.08 | 16 | 664527 | 3136 | 46018383 |
Hypoacusis | 12.30 | 11.08 | 217 | 664326 | 20752 | 46000767 |
Aortic arteriosclerosis | 12.30 | 11.08 | 41 | 664502 | 5680 | 46015839 |
CSF cell count increased | 12.30 | 11.08 | 6 | 664537 | 15 | 46021504 |
Middle insomnia | 12.29 | 11.08 | 82 | 664461 | 9433 | 46012086 |
Ischaemia | 12.28 | 11.08 | 28 | 664515 | 4396 | 46017123 |
Herpes zoster meningitis | 12.28 | 11.08 | 9 | 664534 | 57 | 46021462 |
Tuberculosis gastrointestinal | 12.28 | 11.08 | 20 | 664523 | 342 | 46021177 |
Panic reaction | 12.27 | 11.08 | 21 | 664522 | 3668 | 46017851 |
Blood glucose abnormal | 12.26 | 11.08 | 51 | 664492 | 6621 | 46014898 |
Cellulitis | 12.26 | 11.08 | 1161 | 663382 | 69127 | 45952392 |
Ileal perforation | 12.24 | 11.08 | 20 | 664523 | 343 | 46021176 |
Lymphangitis | 12.24 | 11.08 | 34 | 664509 | 856 | 46020663 |
Vulval cancer | 12.22 | 11.08 | 29 | 664514 | 661 | 46020858 |
Swollen joint count | 12.22 | 11.08 | 17 | 664526 | 251 | 46021268 |
Creatinine urine abnormal | 12.19 | 11.08 | 7 | 664536 | 27 | 46021492 |
Molluscum contagiosum | 12.19 | 11.08 | 15 | 664528 | 195 | 46021324 |
Drug ineffective for unapproved indication | 12.18 | 11.08 | 313 | 664230 | 16100 | 46005419 |
Anal incontinence | 12.16 | 11.08 | 108 | 664435 | 11670 | 46009849 |
Medulloblastoma recurrent | 12.13 | 11.08 | 10 | 664533 | 77 | 46021442 |
Onychomadesis | 12.12 | 11.08 | 76 | 664467 | 2787 | 46018732 |
Non-cardiac chest pain | 12.10 | 11.08 | 45 | 664498 | 6033 | 46015486 |
Poor quality product administered | 12.09 | 11.08 | 15 | 664528 | 2994 | 46018525 |
Feeling cold | 12.08 | 11.08 | 191 | 664352 | 18580 | 46002939 |
Graft versus host disease in lung | 12.08 | 11.08 | 19 | 664524 | 315 | 46021204 |
Injection site vesicles | 12.07 | 11.08 | 72 | 664471 | 2593 | 46018926 |
Solar urticaria | 12.07 | 11.08 | 8 | 664535 | 42 | 46021477 |
Complicated appendicitis | 12.05 | 11.08 | 5 | 664538 | 7 | 46021512 |
Laryngitis | 12.04 | 11.08 | 193 | 664350 | 9123 | 46012396 |
Laryngitis viral | 12.03 | 11.08 | 6 | 664537 | 16 | 46021503 |
Application site vesicles | 12.03 | 11.08 | 3 | 664540 | 1461 | 46020058 |
Bronchopleural fistula | 12.02 | 11.08 | 16 | 664527 | 226 | 46021293 |
Abscess rupture | 12.02 | 11.08 | 15 | 664528 | 198 | 46021321 |
Parapsoriasis | 12.01 | 11.08 | 11 | 664532 | 99 | 46021420 |
Photopsia | 12.01 | 11.08 | 24 | 664519 | 3952 | 46017567 |
Eczema | 12.01 | 11.08 | 211 | 664332 | 20189 | 46001330 |
Diffuse axonal injury | 12.00 | 11.08 | 7 | 664536 | 28 | 46021491 |
Sluggishness | 11.99 | 11.08 | 31 | 664512 | 4660 | 46016859 |
Blood creatine increased | 11.99 | 11.08 | 30 | 664513 | 4560 | 46016959 |
Generalised oedema | 11.98 | 11.08 | 139 | 664404 | 14260 | 46007259 |
Candida test positive | 11.97 | 11.08 | 35 | 664508 | 908 | 46020611 |
Infusion site infection | 11.96 | 11.08 | 3 | 664540 | 1456 | 46020063 |
Peritonitis | 11.95 | 11.08 | 215 | 664328 | 20499 | 46001020 |
Infected bite | 11.95 | 11.08 | 44 | 664499 | 1291 | 46020228 |
Brain injury | 11.94 | 11.08 | 46 | 664497 | 6104 | 46015415 |
Bronchioloalveolar carcinoma | 11.93 | 11.08 | 10 | 664533 | 79 | 46021440 |
Therapeutic response delayed | 11.89 | 11.08 | 25 | 664518 | 524 | 46020995 |
Retroperitoneal haematoma | 11.88 | 11.08 | 12 | 664531 | 2628 | 46018891 |
Device physical property issue | 11.84 | 11.08 | 3 | 664540 | 1446 | 46020073 |
Polymyositis | 11.84 | 11.08 | 50 | 664493 | 1565 | 46019954 |
Kidney infection | 11.83 | 11.08 | 318 | 664225 | 16471 | 46005048 |
Large intestine anastomosis | 11.81 | 11.08 | 7 | 664536 | 29 | 46021490 |
Cardiac failure chronic | 11.77 | 11.08 | 20 | 664523 | 3504 | 46018015 |
Human herpesvirus 6 infection | 11.77 | 11.08 | 67 | 664476 | 2372 | 46019147 |
Toxic leukoencephalopathy | 11.76 | 11.08 | 25 | 664518 | 528 | 46020991 |
Breast cancer in situ | 11.75 | 11.08 | 47 | 664496 | 1435 | 46020084 |
Initial insomnia | 11.70 | 11.08 | 29 | 664514 | 4423 | 46017096 |
Staphylococcal sepsis | 11.68 | 11.08 | 161 | 664382 | 7371 | 46014148 |
Conjunctival deposit | 11.67 | 11.08 | 5 | 664538 | 8 | 46021511 |
Tubal rupture | 11.67 | 11.08 | 5 | 664538 | 8 | 46021511 |
Torulopsis infection | 11.67 | 11.08 | 5 | 664538 | 8 | 46021511 |
Cryptococcus test positive | 11.67 | 11.08 | 5 | 664538 | 8 | 46021511 |
Intestinal adenocarcinoma | 11.66 | 11.08 | 13 | 664530 | 151 | 46021368 |
Subarachnoid haemorrhage | 11.63 | 11.08 | 102 | 664441 | 11051 | 46010468 |
Human bocavirus infection | 11.62 | 11.08 | 19 | 664524 | 326 | 46021193 |
C-reactive protein | 11.62 | 11.08 | 19 | 664524 | 326 | 46021193 |
Retinal injury | 11.58 | 11.08 | 15 | 664528 | 206 | 46021313 |
Bone sarcoma | 11.54 | 11.08 | 6 | 664537 | 18 | 46021501 |
Genital tract inflammation | 11.54 | 11.08 | 6 | 664537 | 18 | 46021501 |
Diabetic eye disease | 11.53 | 11.08 | 13 | 664530 | 153 | 46021366 |
Polydipsia | 11.52 | 11.08 | 18 | 664525 | 3261 | 46018258 |
Eye pain | 11.50 | 11.08 | 306 | 664237 | 27634 | 45993885 |
Haemoperitoneum | 11.50 | 11.08 | 11 | 664532 | 2471 | 46019048 |
Streptococcal infection | 11.47 | 11.08 | 113 | 664430 | 4765 | 46016754 |
Affect lability | 11.46 | 11.08 | 67 | 664476 | 7953 | 46013566 |
Cushingoid | 11.43 | 11.08 | 138 | 664405 | 6128 | 46015391 |
Gastric neoplasm | 11.42 | 11.08 | 17 | 664526 | 268 | 46021251 |
Orthopnoea | 11.41 | 11.08 | 44 | 664499 | 5836 | 46015683 |
Mouth swelling | 11.37 | 11.08 | 22 | 664521 | 3667 | 46017852 |
Pancreatolithiasis | 11.37 | 11.08 | 16 | 664527 | 239 | 46021280 |
Hydronephrosis | 11.36 | 11.08 | 73 | 664470 | 8472 | 46013047 |
Type I hypersensitivity | 11.34 | 11.08 | 10 | 664533 | 2336 | 46019183 |
Thromboangiitis obliterans | 11.31 | 11.08 | 5 | 664538 | 9 | 46021510 |
Local reaction | 11.31 | 11.08 | 22 | 664521 | 435 | 46021084 |
Herpes simplex meningoencephalitis | 11.30 | 11.08 | 7 | 664536 | 32 | 46021487 |
Gallbladder disorder | 11.28 | 11.08 | 178 | 664365 | 17320 | 46004199 |
Retinal deposits | 11.25 | 11.08 | 9 | 664534 | 66 | 46021453 |
Urine analysis abnormal | 11.25 | 11.08 | 27 | 664516 | 4163 | 46017356 |
Conduction disorder | 11.22 | 11.08 | 3 | 664540 | 1395 | 46020124 |
Felty's syndrome | 11.20 | 11.08 | 11 | 664532 | 109 | 46021410 |
Medical device pain | 11.19 | 11.08 | 4 | 664539 | 1542 | 46019977 |
Infective exacerbation of bronchiectasis | 11.19 | 11.08 | 20 | 664523 | 370 | 46021149 |
Ventricular hypokinesia | 11.17 | 11.08 | 26 | 664517 | 4052 | 46017467 |
Device alarm issue | 11.13 | 11.08 | 3 | 664540 | 1387 | 46020132 |
Localised oedema | 11.13 | 11.08 | 36 | 664507 | 5033 | 46016486 |
Rectal cancer metastatic | 11.13 | 11.08 | 16 | 664527 | 244 | 46021275 |
Flank pain | 11.12 | 11.08 | 112 | 664431 | 11801 | 46009718 |
Psoas abscess | 11.11 | 11.08 | 20 | 664523 | 372 | 46021147 |
Parkinson's disease | 11.11 | 11.08 | 4 | 664539 | 1535 | 46019984 |
Contusion | 11.09 | 11.08 | 1083 | 663460 | 86404 | 45935115 |
Drug level increased | 11.09 | 11.08 | 190 | 664353 | 18251 | 46003268 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug ineffective | 4436.93 | 11.18 | 9140 | 241832 | 331247 | 29370259 |
Rheumatoid arthritis | 2999.13 | 11.18 | 2597 | 248375 | 38600 | 29662906 |
Drug intolerance | 1384.03 | 11.18 | 1799 | 249173 | 43492 | 29658014 |
Death | 1294.36 | 11.18 | 695 | 250277 | 356588 | 29344918 |
Joint swelling | 1281.70 | 11.18 | 1765 | 249207 | 45181 | 29656325 |
Synovitis | 997.57 | 11.18 | 752 | 250220 | 9031 | 29692475 |
Arthralgia | 894.03 | 11.18 | 2832 | 248140 | 132959 | 29568547 |
Treatment failure | 858.90 | 11.18 | 1245 | 249727 | 33434 | 29668072 |
Therapeutic product effect incomplete | 799.33 | 11.18 | 1188 | 249784 | 32646 | 29668860 |
Psoriatic arthropathy | 756.05 | 11.18 | 790 | 250182 | 14971 | 29686535 |
Psoriasis | 755.44 | 11.18 | 1311 | 249661 | 41195 | 29660311 |
Completed suicide | 685.79 | 11.18 | 36 | 250936 | 99456 | 29602050 |
Drug abuse | 649.50 | 11.18 | 7 | 250965 | 82065 | 29619441 |
Therapeutic product effect decreased | 637.17 | 11.18 | 986 | 249986 | 28090 | 29673416 |
Musculoskeletal stiffness | 627.46 | 11.18 | 1099 | 249873 | 34782 | 29666724 |
Mucosal inflammation | 604.78 | 11.18 | 988 | 249984 | 29506 | 29672000 |
Acute graft versus host disease | 558.71 | 11.18 | 433 | 250539 | 5431 | 29696075 |
Contraindicated product administered | 553.21 | 11.18 | 702 | 250270 | 16529 | 29684977 |
Drug hypersensitivity | 489.68 | 11.18 | 1472 | 249500 | 67047 | 29634459 |
Arthropathy | 466.82 | 11.18 | 712 | 250260 | 20015 | 29681491 |
Hypotension | 416.19 | 11.18 | 649 | 250323 | 199916 | 29501590 |
Chronic graft versus host disease | 396.43 | 11.18 | 306 | 250666 | 3813 | 29697693 |
Stomatitis | 372.91 | 11.18 | 907 | 250065 | 36372 | 29665134 |
Arthritis | 371.40 | 11.18 | 704 | 250268 | 23697 | 29677809 |
Lymphoproliferative disorder | 356.90 | 11.18 | 230 | 250742 | 2100 | 29699406 |
Bone erosion | 343.00 | 11.18 | 223 | 250749 | 2070 | 29699436 |
Dyspnoea | 337.40 | 11.18 | 1543 | 249429 | 331752 | 29369754 |
Rhabdomyolysis | 327.26 | 11.18 | 67 | 250905 | 63513 | 29637993 |
Hyperkalaemia | 322.76 | 11.18 | 78 | 250894 | 65932 | 29635574 |
Posterior reversible encephalopathy syndrome | 321.92 | 11.18 | 381 | 250591 | 8326 | 29693180 |
Fall | 319.04 | 11.18 | 653 | 250319 | 181219 | 29520287 |
Constipation | 318.77 | 11.18 | 286 | 250686 | 112620 | 29588886 |
Dehydration | 318.68 | 11.18 | 339 | 250633 | 123200 | 29578306 |
Febrile neutropenia | 317.53 | 11.18 | 1745 | 249227 | 104948 | 29596558 |
Leukoencephalopathy | 316.45 | 11.18 | 265 | 250707 | 3737 | 29697769 |
Plasma cell myeloma | 295.32 | 11.18 | 47 | 250925 | 53415 | 29648091 |
Product use in unapproved indication | 293.74 | 11.18 | 1310 | 249662 | 72383 | 29629123 |
C-reactive protein abnormal | 287.37 | 11.18 | 291 | 250681 | 5302 | 29696204 |
Drug clearance decreased | 282.83 | 11.18 | 160 | 250812 | 1123 | 29700383 |
Graft versus host disease | 281.59 | 11.18 | 385 | 250587 | 9765 | 29691741 |
Cardiac failure congestive | 277.40 | 11.18 | 183 | 250789 | 84224 | 29617282 |
Apparent death | 272.77 | 11.18 | 231 | 250741 | 3311 | 29698195 |
Dizziness | 268.66 | 11.18 | 793 | 250179 | 194116 | 29507390 |
Confusional state | 267.39 | 11.18 | 449 | 250523 | 134385 | 29567121 |
Acute graft versus host disease in skin | 259.96 | 11.18 | 250 | 250722 | 4266 | 29697240 |
Acute kidney injury | 255.05 | 11.18 | 1305 | 249667 | 272537 | 29428969 |
Pain | 249.84 | 11.18 | 2373 | 248599 | 170268 | 29531238 |
Cardiac arrest | 248.16 | 11.18 | 247 | 250725 | 92603 | 29608903 |
Venoocclusive liver disease | 240.55 | 11.18 | 287 | 250685 | 6326 | 29695180 |
Liver function test increased | 232.56 | 11.18 | 371 | 250601 | 10845 | 29690661 |
International normalised ratio increased | 230.24 | 11.18 | 58 | 250914 | 47681 | 29653825 |
Pain in extremity | 224.59 | 11.18 | 1637 | 249335 | 108584 | 29592922 |
Febrile bone marrow aplasia | 224.41 | 11.18 | 307 | 250665 | 7790 | 29693716 |
Pancytopenia | 224.01 | 11.18 | 1347 | 249625 | 83705 | 29617801 |
Intentional overdose | 221.28 | 11.18 | 40 | 250932 | 41441 | 29660065 |
Pneumocystis jirovecii pneumonia | 220.83 | 11.18 | 461 | 250511 | 16659 | 29684847 |
Anaemia | 218.82 | 11.18 | 948 | 250024 | 207044 | 29494462 |
Bradycardia | 218.06 | 11.18 | 140 | 250832 | 65386 | 29636120 |
Overdose | 217.82 | 11.18 | 231 | 250741 | 84106 | 29617400 |
Syncope | 212.15 | 11.18 | 239 | 250733 | 84664 | 29616842 |
Epstein-Barr virus infection | 210.10 | 11.18 | 270 | 250702 | 6436 | 29695070 |
Hypofibrinogenaemia | 210.04 | 11.18 | 145 | 250827 | 1500 | 29700006 |
Hallucination | 208.70 | 11.18 | 75 | 250897 | 48984 | 29652522 |
Red blood cell sedimentation rate increased | 207.34 | 11.18 | 280 | 250692 | 7015 | 29694491 |
Diarrhoea | 206.52 | 11.18 | 1800 | 249172 | 332303 | 29369203 |
Decreased appetite | 205.60 | 11.18 | 611 | 250361 | 149299 | 29552207 |
Asthenia | 200.48 | 11.18 | 1064 | 249908 | 220226 | 29481280 |
Basal cell carcinoma | 198.35 | 11.18 | 425 | 250547 | 15643 | 29685863 |
Mobility decreased | 197.31 | 11.18 | 571 | 250401 | 25428 | 29676078 |
Pulmonary fibrosis | 196.97 | 11.18 | 421 | 250551 | 15469 | 29686037 |
Atrial fibrillation | 192.90 | 11.18 | 384 | 250588 | 107740 | 29593766 |
Electrocardiogram QT prolonged | 192.34 | 11.18 | 34 | 250938 | 35801 | 29665705 |
Hypoglycaemia | 191.09 | 11.18 | 94 | 250878 | 50887 | 29650619 |
Red blood cell sedimentation rate abnormal | 191.05 | 11.18 | 141 | 250831 | 1634 | 29699872 |
Myelopathy | 190.32 | 11.18 | 146 | 250826 | 1801 | 29699705 |
Bone marrow failure | 185.90 | 11.18 | 611 | 250361 | 29174 | 29672332 |
Loss of personal independence in daily activities | 183.15 | 11.18 | 493 | 250479 | 21042 | 29680464 |
Somnolence | 182.81 | 11.18 | 332 | 250640 | 96431 | 29605075 |
Fatigue | 182.32 | 11.18 | 1764 | 249208 | 318909 | 29382597 |
Haemoglobin decreased | 180.62 | 11.18 | 433 | 250539 | 113665 | 29587841 |
Diverticulitis | 179.23 | 11.18 | 429 | 250543 | 17016 | 29684490 |
Hand deformity | 177.73 | 11.18 | 138 | 250834 | 1735 | 29699771 |
Epstein-Barr virus associated lymphoproliferative disorder | 176.46 | 11.18 | 133 | 250839 | 1595 | 29699911 |
Tuberculosis | 175.52 | 11.18 | 273 | 250699 | 7804 | 29693702 |
Agitation | 173.87 | 11.18 | 120 | 250852 | 53953 | 29647553 |
Cardio-respiratory arrest | 172.84 | 11.18 | 136 | 250836 | 57170 | 29644336 |
Blood glucose increased | 172.14 | 11.18 | 157 | 250815 | 61373 | 29640133 |
Hospitalisation | 168.71 | 11.18 | 80 | 250892 | 44239 | 29657267 |
Joint stiffness | 167.73 | 11.18 | 290 | 250682 | 9071 | 29692435 |
Osteoarthritis | 166.15 | 11.18 | 430 | 250542 | 17919 | 29683587 |
Aggression | 164.67 | 11.18 | 52 | 250920 | 36855 | 29664651 |
Ankylosing spondylitis | 160.36 | 11.18 | 194 | 250778 | 4340 | 29697166 |
Acute lymphocytic leukaemia recurrent | 159.88 | 11.18 | 151 | 250821 | 2516 | 29698990 |
Knee arthroplasty | 159.86 | 11.18 | 216 | 250756 | 5414 | 29696092 |
Gastrointestinal haemorrhage | 159.67 | 11.18 | 284 | 250688 | 83162 | 29618344 |
Diffuse large B-cell lymphoma | 153.89 | 11.18 | 253 | 250719 | 7588 | 29693918 |
Suicide attempt | 152.87 | 11.18 | 58 | 250914 | 36639 | 29664867 |
Malignant neoplasm progression | 149.42 | 11.18 | 234 | 250738 | 72053 | 29629453 |
Hyponatraemia | 149.19 | 11.18 | 207 | 250765 | 66995 | 29634511 |
Off label use | 147.70 | 11.18 | 2918 | 248054 | 246372 | 29455134 |
Infection | 146.69 | 11.18 | 1138 | 249834 | 76936 | 29624570 |
Rheumatoid nodule | 146.37 | 11.18 | 118 | 250854 | 1572 | 29699934 |
Loss of consciousness | 144.89 | 11.18 | 278 | 250694 | 79097 | 29622409 |
Nodule | 144.10 | 11.18 | 189 | 250783 | 4599 | 29696907 |
Neurotoxicity | 142.83 | 11.18 | 331 | 250641 | 12851 | 29688655 |
Blood creatine phosphokinase increased | 142.71 | 11.18 | 96 | 250876 | 43752 | 29657754 |
Angiocentric lymphoma | 142.12 | 11.18 | 64 | 250908 | 254 | 29701252 |
Injection site pain | 140.95 | 11.18 | 565 | 250407 | 29745 | 29671761 |
Foot deformity | 139.79 | 11.18 | 158 | 250814 | 3279 | 29698227 |
Haemophagocytic lymphohistiocytosis | 137.33 | 11.18 | 273 | 250699 | 9518 | 29691988 |
Disability | 137.02 | 11.18 | 177 | 250795 | 4241 | 29697265 |
Anxiety | 136.74 | 11.18 | 348 | 250624 | 89523 | 29611983 |
Graft versus host disease in gastrointestinal tract | 135.02 | 11.18 | 147 | 250825 | 2922 | 29698584 |
Lymphoma | 133.39 | 11.18 | 275 | 250697 | 9846 | 29691660 |
Suicidal ideation | 131.71 | 11.18 | 69 | 250903 | 36045 | 29665461 |
Blood creatinine increased | 131.30 | 11.18 | 364 | 250608 | 91011 | 29610495 |
Inflammation | 129.59 | 11.18 | 443 | 250529 | 21583 | 29679923 |
C-reactive protein increased | 124.36 | 11.18 | 704 | 250268 | 42769 | 29658737 |
Drug interaction | 123.40 | 11.18 | 1074 | 249898 | 198494 | 29503012 |
Cystitis haemorrhagic | 122.95 | 11.18 | 175 | 250797 | 4612 | 29696894 |
Pulmonary tuberculosis | 122.46 | 11.18 | 176 | 250796 | 4681 | 29696825 |
Neuroleptic malignant syndrome | 122.12 | 11.18 | 3 | 250969 | 16292 | 29685214 |
Arthritis bacterial | 121.81 | 11.18 | 168 | 250804 | 4296 | 29697210 |
Sarcoidosis | 120.55 | 11.18 | 131 | 250841 | 2598 | 29698908 |
Gastrointestinal disorder | 117.12 | 11.18 | 507 | 250465 | 27630 | 29673876 |
Cerebrovascular accident | 116.63 | 11.18 | 337 | 250635 | 83140 | 29618366 |
Graft versus host disease in skin | 116.14 | 11.18 | 141 | 250831 | 3166 | 29698340 |
Haematotoxicity | 115.62 | 11.18 | 195 | 250777 | 5975 | 29695531 |
Sedation | 112.45 | 11.18 | 6 | 250966 | 16367 | 29685139 |
Mouth ulceration | 112.32 | 11.18 | 264 | 250708 | 10345 | 29691161 |
Lactic acidosis | 110.37 | 11.18 | 62 | 250910 | 31151 | 29670355 |
Pneumonia aspiration | 109.74 | 11.18 | 93 | 250879 | 37687 | 29663819 |
Myocardial infarction | 109.11 | 11.18 | 612 | 250360 | 125013 | 29576493 |
Herpes zoster | 108.56 | 11.18 | 518 | 250454 | 29425 | 29672081 |
Therapeutic response decreased | 108.52 | 11.18 | 448 | 250524 | 23901 | 29677605 |
Chondropathy | 107.59 | 11.18 | 75 | 250897 | 789 | 29700717 |
Nasopharyngitis | 106.75 | 11.18 | 851 | 250121 | 57998 | 29643508 |
Metabolic acidosis | 106.64 | 11.18 | 94 | 250878 | 37367 | 29664139 |
Drug withdrawal syndrome | 105.84 | 11.18 | 19 | 250953 | 19790 | 29681716 |
Acute graft versus host disease in intestine | 105.46 | 11.18 | 115 | 250857 | 2290 | 29699216 |
Visceral leishmaniasis | 104.35 | 11.18 | 60 | 250912 | 436 | 29701070 |
Juvenile idiopathic arthritis | 103.68 | 11.18 | 79 | 250893 | 964 | 29700542 |
Respiratory arrest | 103.62 | 11.18 | 58 | 250914 | 29200 | 29672306 |
Drug reaction with eosinophilia and systemic symptoms | 103.04 | 11.18 | 55 | 250917 | 28433 | 29673073 |
Product use issue | 102.62 | 11.18 | 699 | 250273 | 45317 | 29656189 |
Rheumatoid factor positive | 101.82 | 11.18 | 60 | 250912 | 459 | 29701047 |
Acute myocardial infarction | 99.58 | 11.18 | 182 | 250790 | 52757 | 29648749 |
Product dose omission issue | 99.57 | 11.18 | 412 | 250560 | 91219 | 29610287 |
Prostate cancer | 99.18 | 11.18 | 431 | 250541 | 23526 | 29677980 |
Sleep disorder due to general medical condition, insomnia type | 97.71 | 11.18 | 81 | 250891 | 1125 | 29700381 |
Grip strength decreased | 97.40 | 11.18 | 105 | 250867 | 2063 | 29699443 |
Cardiac failure | 96.39 | 11.18 | 366 | 250606 | 83052 | 29618454 |
Cutaneous leishmaniasis | 96.14 | 11.18 | 38 | 250934 | 99 | 29701407 |
Histoplasmosis disseminated | 95.79 | 11.18 | 73 | 250899 | 891 | 29700615 |
Skin plaque | 95.71 | 11.18 | 135 | 250837 | 3527 | 29697979 |
Delirium | 95.41 | 11.18 | 120 | 250852 | 40511 | 29660995 |
Intentional product misuse | 95.10 | 11.18 | 90 | 250882 | 34577 | 29666929 |
Coma | 93.39 | 11.18 | 121 | 250851 | 40328 | 29661178 |
Abnormal behaviour | 93.36 | 11.18 | 49 | 250923 | 25574 | 29675932 |
Foetal exposure during pregnancy | 92.89 | 11.18 | 103 | 250869 | 36768 | 29664738 |
Synovial cyst | 91.85 | 11.18 | 92 | 250880 | 1653 | 29699853 |
Sacroiliitis | 91.85 | 11.18 | 68 | 250904 | 792 | 29700714 |
Oxidative stress | 91.18 | 11.18 | 27 | 250945 | 14 | 29701492 |
Immunosuppression | 90.98 | 11.18 | 159 | 250813 | 5016 | 29696490 |
Toxicity to various agents | 89.93 | 11.18 | 1000 | 249972 | 176183 | 29525323 |
Impaired work ability | 89.78 | 11.18 | 166 | 250806 | 5477 | 29696029 |
Tuberculin test positive | 89.68 | 11.18 | 71 | 250901 | 920 | 29700586 |
Dactylitis | 88.93 | 11.18 | 53 | 250919 | 415 | 29701091 |
Musculoskeletal pain | 88.44 | 11.18 | 501 | 250471 | 30439 | 29671067 |
Chest pain | 88.10 | 11.18 | 600 | 250372 | 117027 | 29584479 |
Joint range of motion decreased | 88.09 | 11.18 | 168 | 250804 | 5677 | 29695829 |
Anti-cyclic citrullinated peptide antibody positive | 87.11 | 11.18 | 62 | 250910 | 676 | 29700830 |
Drug specific antibody present | 86.50 | 11.18 | 96 | 250876 | 1951 | 29699555 |
Orthostatic hypotension | 85.69 | 11.18 | 47 | 250925 | 23932 | 29677574 |
Squamous cell carcinoma | 84.47 | 11.18 | 232 | 250740 | 10018 | 29691488 |
Cytomegalovirus infection | 83.97 | 11.18 | 407 | 250565 | 23267 | 29678239 |
Delusion | 83.58 | 11.18 | 4 | 250968 | 11985 | 29689521 |
Polyarthritis | 83.21 | 11.18 | 119 | 250853 | 3150 | 29698356 |
Hypokalaemia | 82.92 | 11.18 | 186 | 250786 | 50006 | 29651500 |
Disseminated tuberculosis | 82.72 | 11.18 | 95 | 250877 | 2007 | 29699499 |
Hepatic enzyme increased | 82.70 | 11.18 | 522 | 250450 | 32972 | 29668534 |
Tenosynovitis | 82.29 | 11.18 | 123 | 250849 | 3392 | 29698114 |
Intentional self-injury | 81.60 | 11.18 | 9 | 250963 | 13523 | 29687983 |
Peripheral swelling | 80.93 | 11.18 | 825 | 250147 | 60249 | 29641257 |
Swelling | 80.51 | 11.18 | 547 | 250425 | 35428 | 29666078 |
Spermatozoa abnormal | 80.19 | 11.18 | 27 | 250945 | 35 | 29701471 |
Joint effusion | 79.85 | 11.18 | 124 | 250848 | 3539 | 29697967 |
Tremor | 79.30 | 11.18 | 343 | 250629 | 75020 | 29626486 |
Disease progression | 78.97 | 11.18 | 372 | 250600 | 79502 | 29622004 |
Epidermal necrosis | 78.18 | 11.18 | 48 | 250924 | 399 | 29701107 |
Pulmonary toxicity | 77.13 | 11.18 | 137 | 250835 | 4379 | 29697127 |
Acute lymphocytic leukaemia | 76.98 | 11.18 | 111 | 250861 | 2961 | 29698545 |
Platelet count decreased | 76.68 | 11.18 | 547 | 250425 | 105582 | 29595924 |
Demyelination | 76.65 | 11.18 | 102 | 250870 | 2518 | 29698988 |
Bone cyst | 76.64 | 11.18 | 51 | 250921 | 494 | 29701012 |
Unevaluable event | 76.60 | 11.18 | 92 | 250880 | 31693 | 29669813 |
Blood urea increased | 76.51 | 11.18 | 90 | 250882 | 31291 | 29670215 |
Psychotic disorder | 75.68 | 11.18 | 43 | 250929 | 21472 | 29680034 |
Chemotherapeutic drug level increased | 74.72 | 11.18 | 37 | 250935 | 190 | 29701316 |
Mycobacterium tuberculosis complex test positive | 74.66 | 11.18 | 63 | 250909 | 898 | 29700608 |
Vein rupture | 74.53 | 11.18 | 53 | 250919 | 577 | 29700929 |
Restlessness | 74.16 | 11.18 | 49 | 250923 | 22550 | 29678956 |
Hypocalcaemia | 73.38 | 11.18 | 44 | 250928 | 21332 | 29680174 |
Serotonin syndrome | 73.30 | 11.18 | 29 | 250943 | 17862 | 29683644 |
Depressed level of consciousness | 73.13 | 11.18 | 130 | 250842 | 38092 | 29663414 |
Dislocation of vertebra | 73.05 | 11.18 | 44 | 250928 | 352 | 29701154 |
Hyperglycaemia | 71.69 | 11.18 | 115 | 250857 | 35085 | 29666421 |
Sensitivity to weather change | 71.69 | 11.18 | 74 | 250898 | 1380 | 29700126 |
Bladder transitional cell carcinoma | 70.99 | 11.18 | 95 | 250877 | 2358 | 29699148 |
Leukaemia recurrent | 70.82 | 11.18 | 76 | 250896 | 1485 | 29700021 |
Pulmonary mass | 70.60 | 11.18 | 226 | 250746 | 10636 | 29690870 |
Malignant melanoma | 70.52 | 11.18 | 177 | 250795 | 7234 | 29694272 |
Cytogenetic abnormality | 69.95 | 11.18 | 56 | 250916 | 738 | 29700768 |
Hepatotoxicity | 69.49 | 11.18 | 319 | 250653 | 17826 | 29683680 |
Urinary retention | 69.47 | 11.18 | 105 | 250867 | 32812 | 29668694 |
Atlantoaxial instability | 69.42 | 11.18 | 40 | 250932 | 292 | 29701214 |
Cardiac disorder | 69.07 | 11.18 | 144 | 250828 | 39749 | 29661757 |
Insomnia | 68.92 | 11.18 | 478 | 250494 | 92858 | 29608648 |
Enthesopathy | 68.47 | 11.18 | 102 | 250870 | 2804 | 29698702 |
Product quality issue | 68.25 | 11.18 | 36 | 250936 | 18738 | 29682768 |
Spinal instability | 67.88 | 11.18 | 40 | 250932 | 306 | 29701200 |
Injection site swelling | 67.71 | 11.18 | 194 | 250778 | 8586 | 29692920 |
Angioedema | 67.55 | 11.18 | 115 | 250857 | 34269 | 29667237 |
Injury | 67.50 | 11.18 | 50 | 250922 | 21681 | 29679825 |
Mineral metabolism disorder | 67.45 | 11.18 | 40 | 250932 | 310 | 29701196 |
Oedema peripheral | 67.30 | 11.18 | 565 | 250407 | 105267 | 29596239 |
Venoocclusive disease | 66.98 | 11.18 | 95 | 250877 | 2495 | 29699011 |
Central nervous system lymphoma | 66.95 | 11.18 | 57 | 250915 | 823 | 29700683 |
Chronic kidney disease | 66.85 | 11.18 | 135 | 250837 | 37703 | 29663803 |
X-ray abnormal | 66.70 | 11.18 | 46 | 250926 | 475 | 29701031 |
Fear of injection | 66.37 | 11.18 | 50 | 250922 | 599 | 29700907 |
Complications of bone marrow transplant | 66.37 | 11.18 | 34 | 250938 | 190 | 29701316 |
Dyskinesia | 65.57 | 11.18 | 52 | 250920 | 21782 | 29679724 |
Blood potassium increased | 65.25 | 11.18 | 27 | 250945 | 16186 | 29685320 |
Hip arthroplasty | 64.57 | 11.18 | 114 | 250858 | 3626 | 29697880 |
Rheumatoid factor negative | 64.22 | 11.18 | 46 | 250926 | 507 | 29700999 |
Joint ankylosis | 63.71 | 11.18 | 38 | 250934 | 298 | 29701208 |
Intervertebral disc space narrowing | 63.70 | 11.18 | 49 | 250923 | 607 | 29700899 |
Onychoclasis | 63.65 | 11.18 | 74 | 250898 | 1585 | 29699921 |
Uveitis | 63.18 | 11.18 | 141 | 250831 | 5336 | 29696170 |
Wrist deformity | 63.09 | 11.18 | 38 | 250934 | 304 | 29701202 |
Vomiting | 63.02 | 11.18 | 1383 | 249589 | 218435 | 29483071 |
Finger deformity | 63.00 | 11.18 | 58 | 250914 | 934 | 29700572 |
Coronary artery disease | 62.80 | 11.18 | 210 | 250762 | 49502 | 29652004 |
Dysgeusia | 62.77 | 11.18 | 69 | 250903 | 24732 | 29676774 |
Mucocutaneous ulceration | 61.98 | 11.18 | 26 | 250946 | 83 | 29701423 |
Haemorrhage | 61.45 | 11.18 | 190 | 250782 | 45889 | 29655617 |
Renal impairment | 61.22 | 11.18 | 433 | 250539 | 83751 | 29617755 |
Multiple sclerosis relapse | 61.20 | 11.18 | 9 | 250963 | 10853 | 29690653 |
Condition aggravated | 61.19 | 11.18 | 1550 | 249422 | 136316 | 29565190 |
Pleurisy | 60.68 | 11.18 | 126 | 250846 | 4534 | 29696972 |
Lymphadenopathy | 60.23 | 11.18 | 380 | 250592 | 23996 | 29677510 |
Haematocrit decreased | 60.01 | 11.18 | 103 | 250869 | 30596 | 29670910 |
Blood pressure fluctuation | 59.98 | 11.18 | 298 | 250674 | 17205 | 29684301 |
Hallucination, visual | 59.91 | 11.18 | 30 | 250942 | 16083 | 29685423 |
Melaena | 59.67 | 11.18 | 113 | 250859 | 32324 | 29669182 |
Nightmare | 59.51 | 11.18 | 14 | 250958 | 12062 | 29689444 |
Post transplant lymphoproliferative disorder | 59.42 | 11.18 | 135 | 250837 | 5171 | 29696335 |
Respiratory depression | 59.40 | 11.18 | 12 | 250960 | 11491 | 29690015 |
Stevens-Johnson syndrome | 59.06 | 11.18 | 37 | 250935 | 17519 | 29683987 |
Oedema | 58.96 | 11.18 | 175 | 250797 | 42818 | 29658688 |
Hypersensitivity | 58.36 | 11.18 | 701 | 250271 | 53327 | 29648179 |
Depression | 58.30 | 11.18 | 481 | 250491 | 89956 | 29611550 |
Haematemesis | 57.82 | 11.18 | 81 | 250891 | 26122 | 29675384 |
Abscess | 57.78 | 11.18 | 201 | 250771 | 9877 | 29691629 |
White blood cell count increased | 57.71 | 11.18 | 157 | 250815 | 39516 | 29661990 |
Myalgia | 57.39 | 11.18 | 391 | 250581 | 76276 | 29625230 |
Blood pressure decreased | 57.34 | 11.18 | 202 | 250770 | 46873 | 29654633 |
Joint destruction | 57.30 | 11.18 | 31 | 250941 | 197 | 29701309 |
Injection site haemorrhage | 57.16 | 11.18 | 170 | 250802 | 7685 | 29693821 |
Acute graft versus host disease in liver | 56.80 | 11.18 | 61 | 250911 | 1193 | 29700313 |
Pneumonia legionella | 56.62 | 11.18 | 68 | 250904 | 1509 | 29699997 |
Balance disorder | 56.46 | 11.18 | 140 | 250832 | 36353 | 29665153 |
Diabetic ketoacidosis | 56.15 | 11.18 | 32 | 250940 | 15954 | 29685552 |
Hepatic steatosis | 55.86 | 11.18 | 259 | 250713 | 14534 | 29686972 |
Extrapyramidal disorder | 55.54 | 11.18 | 11 | 250961 | 10682 | 29690824 |
Acne cystic | 55.24 | 11.18 | 40 | 250932 | 449 | 29701057 |
Skin lesion | 55.18 | 11.18 | 303 | 250669 | 18191 | 29683315 |
Clinodactyly | 55.04 | 11.18 | 26 | 250946 | 118 | 29701388 |
Skin ulcer | 55.03 | 11.18 | 307 | 250665 | 18542 | 29682964 |
Blood potassium decreased | 54.84 | 11.18 | 36 | 250936 | 16626 | 29684880 |
Schizophrenia | 54.60 | 11.18 | 6 | 250966 | 9042 | 29692464 |
Histoplasmosis | 54.58 | 11.18 | 60 | 250912 | 1206 | 29700300 |
Injection site bruising | 54.53 | 11.18 | 160 | 250812 | 7178 | 29694328 |
Hypertriglyceridaemia | 54.01 | 11.18 | 170 | 250802 | 7928 | 29693578 |
Chronic graft versus host disease in skin | 53.48 | 11.18 | 46 | 250926 | 674 | 29700832 |
Mycobacterial infection | 53.44 | 11.18 | 69 | 250903 | 1652 | 29699854 |
Inappropriate schedule of product administration | 53.24 | 11.18 | 538 | 250434 | 39190 | 29662316 |
Limb discomfort | 53.20 | 11.18 | 182 | 250790 | 8868 | 29692638 |
Rheumatoid lung | 53.15 | 11.18 | 34 | 250938 | 306 | 29701200 |
Atrial flutter | 52.48 | 11.18 | 27 | 250945 | 14254 | 29687252 |
Ventricular tachycardia | 52.42 | 11.18 | 74 | 250898 | 23788 | 29677718 |
Drug eruption | 52.20 | 11.18 | 287 | 250685 | 17239 | 29684267 |
Disease recurrence | 52.05 | 11.18 | 246 | 250726 | 13915 | 29687591 |
Hypomagnesaemia | 51.79 | 11.18 | 38 | 250934 | 16560 | 29684946 |
Engraftment syndrome | 51.54 | 11.18 | 48 | 250924 | 785 | 29700721 |
Disorientation | 51.42 | 11.18 | 117 | 250855 | 31301 | 29670205 |
Thrombotic microangiopathy | 51.35 | 11.18 | 174 | 250798 | 8436 | 29693070 |
Sinus bradycardia | 51.23 | 11.18 | 17 | 250955 | 11678 | 29689828 |
Pulmonary oedema | 50.72 | 11.18 | 193 | 250779 | 43782 | 29657724 |
Fluid retention | 50.59 | 11.18 | 82 | 250890 | 24916 | 29676590 |
Adenovirus infection | 50.50 | 11.18 | 111 | 250861 | 4157 | 29697349 |
Full blood count decreased | 50.33 | 11.18 | 35 | 250937 | 15682 | 29685824 |
Cardiogenic shock | 49.58 | 11.18 | 41 | 250931 | 16820 | 29684686 |
Anhedonia | 49.38 | 11.18 | 6 | 250966 | 8363 | 29693143 |
Mental status changes | 49.36 | 11.18 | 153 | 250819 | 36926 | 29664580 |
Photosensitivity reaction | 49.35 | 11.18 | 186 | 250786 | 9508 | 29691998 |
General physical health deterioration | 49.07 | 11.18 | 568 | 250404 | 99376 | 29602130 |
Abdominal distension | 48.69 | 11.18 | 207 | 250765 | 45502 | 29656004 |
Superior sagittal sinus thrombosis | 48.28 | 11.18 | 31 | 250941 | 281 | 29701225 |
Irritability | 48.17 | 11.18 | 74 | 250898 | 22976 | 29678530 |
Squamous cell carcinoma of lung | 48.04 | 11.18 | 66 | 250906 | 1681 | 29699825 |
Kidney transplant rejection | 47.90 | 11.18 | 4 | 250968 | 7505 | 29694001 |
Aplasia | 47.77 | 11.18 | 105 | 250867 | 3932 | 29697574 |
Myoclonus | 47.69 | 11.18 | 26 | 250946 | 13286 | 29688220 |
Miosis | 47.33 | 11.18 | 5 | 250967 | 7771 | 29693735 |
Bursitis | 47.33 | 11.18 | 113 | 250859 | 4473 | 29697033 |
Blood sodium decreased | 47.31 | 11.18 | 38 | 250934 | 15818 | 29685688 |
Lung neoplasm malignant | 47.23 | 11.18 | 251 | 250721 | 14881 | 29686625 |
Cutaneous T-cell lymphoma | 47.01 | 11.18 | 57 | 250915 | 1278 | 29700228 |
Latent tuberculosis | 46.85 | 11.18 | 48 | 250924 | 887 | 29700619 |
Colitis ulcerative | 46.83 | 11.18 | 242 | 250730 | 14192 | 29687314 |
Skin cancer | 46.71 | 11.18 | 160 | 250812 | 7801 | 29693705 |
Epstein Barr virus positive mucocutaneous ulcer | 46.59 | 11.18 | 28 | 250944 | 223 | 29701283 |
Dystonia | 46.52 | 11.18 | 12 | 250960 | 9715 | 29691791 |
Hypovolaemia | 46.52 | 11.18 | 8 | 250964 | 8597 | 29692909 |
Joint arthroplasty | 46.45 | 11.18 | 40 | 250932 | 587 | 29700919 |
Lupus-like syndrome | 46.31 | 11.18 | 72 | 250900 | 2057 | 29699449 |
Pulmonary hypertension | 45.96 | 11.18 | 55 | 250917 | 18981 | 29682525 |
Seizure | 45.91 | 11.18 | 566 | 250406 | 97909 | 29603597 |
Mass | 45.90 | 11.18 | 148 | 250824 | 6992 | 29694514 |
Cognitive disorder | 45.83 | 11.18 | 80 | 250892 | 23610 | 29677896 |
Angioimmunoblastic T-cell lymphoma | 45.80 | 11.18 | 32 | 250940 | 338 | 29701168 |
Flushing | 44.95 | 11.18 | 114 | 250858 | 29378 | 29672128 |
Osteonecrosis of jaw | 44.73 | 11.18 | 54 | 250918 | 18564 | 29682942 |
Intestinal polyp | 44.68 | 11.18 | 46 | 250926 | 855 | 29700651 |
Blood glucose decreased | 44.61 | 11.18 | 27 | 250945 | 13026 | 29688480 |
Cytomegalovirus chorioretinitis | 44.48 | 11.18 | 90 | 250882 | 3178 | 29698328 |
Tachycardia | 44.47 | 11.18 | 399 | 250573 | 73340 | 29628166 |
B-cell lymphoma | 44.27 | 11.18 | 109 | 250863 | 4401 | 29697105 |
Urinary tract infection | 44.24 | 11.18 | 399 | 250573 | 73260 | 29628246 |
Swollen tongue | 44.10 | 11.18 | 28 | 250944 | 13164 | 29688342 |
Arthritis infective | 43.63 | 11.18 | 80 | 250892 | 2622 | 29698884 |
Lung disorder | 43.54 | 11.18 | 429 | 250543 | 31040 | 29670466 |
Muscle rigidity | 43.08 | 11.18 | 16 | 250956 | 10245 | 29691261 |
Seronegative arthritis | 43.04 | 11.18 | 43 | 250929 | 770 | 29700736 |
Vision blurred | 42.94 | 11.18 | 192 | 250780 | 41624 | 29659882 |
Transient ischaemic attack | 42.75 | 11.18 | 92 | 250880 | 25108 | 29676398 |
Abscess limb | 42.39 | 11.18 | 86 | 250886 | 3043 | 29698463 |
Haemoptysis | 42.25 | 11.18 | 127 | 250845 | 30951 | 29670555 |
Rash maculo-papular | 42.12 | 11.18 | 94 | 250878 | 25324 | 29676182 |
Upper gastrointestinal haemorrhage | 42.06 | 11.18 | 75 | 250897 | 21953 | 29679553 |
Fear | 42.01 | 11.18 | 19 | 250953 | 10806 | 29690700 |
Dysphagia | 42.00 | 11.18 | 290 | 250682 | 56408 | 29645098 |
Unresponsive to stimuli | 41.93 | 11.18 | 100 | 250872 | 26319 | 29675187 |
Foetal methotrexate syndrome | 41.70 | 11.18 | 11 | 250961 | 0 | 29701506 |
Subdural haematoma | 41.51 | 11.18 | 59 | 250913 | 18913 | 29682593 |
Immunodeficiency | 41.32 | 11.18 | 103 | 250869 | 4191 | 29697315 |
Arrhythmia | 41.28 | 11.18 | 141 | 250831 | 33028 | 29668478 |
Inflammatory marker increased | 41.27 | 11.18 | 86 | 250886 | 3102 | 29698404 |
Pulmonary thrombosis | 41.24 | 11.18 | 132 | 250840 | 6211 | 29695295 |
Tooth fracture | 41.07 | 11.18 | 87 | 250885 | 3175 | 29698331 |
Paranoia | 40.94 | 11.18 | 17 | 250955 | 10171 | 29691335 |
Palpitations | 40.92 | 11.18 | 144 | 250828 | 33429 | 29668077 |
Arachnoiditis | 40.91 | 11.18 | 29 | 250943 | 314 | 29701192 |
Erectile dysfunction | 40.90 | 11.18 | 55 | 250917 | 18047 | 29683459 |
Anal fistula | 40.90 | 11.18 | 98 | 250874 | 3888 | 29697618 |
Haematuria | 40.73 | 11.18 | 215 | 250757 | 44619 | 29656887 |
Epstein-Barr viraemia | 40.51 | 11.18 | 44 | 250928 | 872 | 29700634 |
Acute myeloid leukaemia | 40.40 | 11.18 | 274 | 250698 | 17732 | 29683774 |
Alanine aminotransferase abnormal | 40.36 | 11.18 | 76 | 250896 | 2543 | 29698963 |
Hepatic encephalopathy | 39.91 | 11.18 | 36 | 250936 | 14156 | 29687350 |
Craniosynostosis | 39.83 | 11.18 | 25 | 250947 | 217 | 29701289 |
Poisoning | 39.67 | 11.18 | 23 | 250949 | 11359 | 29690147 |
Wheezing | 39.54 | 11.18 | 130 | 250842 | 30808 | 29670698 |
Decreased immune responsiveness | 39.31 | 11.18 | 51 | 250921 | 1227 | 29700279 |
Viral haemorrhagic cystitis | 39.20 | 11.18 | 42 | 250930 | 819 | 29700687 |
Cytology abnormal | 39.11 | 11.18 | 30 | 250942 | 370 | 29701136 |
Renal injury | 39.07 | 11.18 | 25 | 250947 | 11704 | 29689802 |
Treatment noncompliance | 38.97 | 11.18 | 97 | 250875 | 25156 | 29676350 |
Peritoneal tuberculosis | 38.84 | 11.18 | 30 | 250942 | 374 | 29701132 |
Rash | 38.75 | 11.18 | 1269 | 249703 | 190620 | 29510886 |
Lymph node tuberculosis | 38.51 | 11.18 | 32 | 250940 | 446 | 29701060 |
Musculoskeletal discomfort | 38.18 | 11.18 | 128 | 250844 | 6172 | 29695334 |
Joint lock | 38.02 | 11.18 | 46 | 250926 | 1029 | 29700477 |
Pustular psoriasis | 37.97 | 11.18 | 57 | 250915 | 1578 | 29699928 |
Central nervous system leukaemia | 37.84 | 11.18 | 25 | 250947 | 239 | 29701267 |
Jaundice | 37.83 | 11.18 | 142 | 250830 | 32344 | 29669162 |
Non-Hodgkin's lymphoma | 37.78 | 11.18 | 59 | 250913 | 1692 | 29699814 |
Angina pectoris | 37.75 | 11.18 | 124 | 250848 | 29394 | 29672112 |
Arthrodesis | 37.62 | 11.18 | 30 | 250942 | 393 | 29701113 |
Injection site erythema | 37.55 | 11.18 | 221 | 250751 | 13613 | 29687893 |
Graft versus host disease in liver | 37.28 | 11.18 | 44 | 250928 | 958 | 29700548 |
Acute promyelocytic leukaemia | 37.21 | 11.18 | 34 | 250938 | 542 | 29700964 |
Head injury | 37.17 | 11.18 | 53 | 250919 | 16967 | 29684539 |
Therapy non-responder | 37.15 | 11.18 | 394 | 250578 | 29059 | 29672447 |
Cytomegalovirus viraemia | 37.05 | 11.18 | 119 | 250853 | 5610 | 29695896 |
Fungal infection | 36.75 | 11.18 | 217 | 250755 | 13383 | 29688123 |
Fibromyalgia | 36.71 | 11.18 | 73 | 250899 | 2545 | 29698961 |
Eosinophilia | 36.68 | 11.18 | 82 | 250890 | 22078 | 29679428 |
Clear cell renal cell carcinoma | 36.51 | 11.18 | 42 | 250930 | 889 | 29700617 |
Molluscum contagiosum | 36.50 | 11.18 | 25 | 250947 | 255 | 29701251 |
Amnesia | 36.31 | 11.18 | 95 | 250877 | 24226 | 29677280 |
Depressed mood | 36.23 | 11.18 | 54 | 250918 | 16975 | 29684531 |
Cerebral haemorrhage | 36.22 | 11.18 | 147 | 250825 | 32740 | 29668766 |
Red blood cell count decreased | 36.18 | 11.18 | 107 | 250865 | 26214 | 29675292 |
Erythrodermic psoriasis | 36.17 | 11.18 | 38 | 250934 | 724 | 29700782 |
Therapy partial responder | 36.01 | 11.18 | 89 | 250883 | 3602 | 29697904 |
Oral herpes | 35.88 | 11.18 | 100 | 250872 | 4355 | 29697151 |
Glioma | 35.82 | 11.18 | 26 | 250946 | 293 | 29701213 |
Human herpesvirus 8 infection | 35.67 | 11.18 | 36 | 250936 | 653 | 29700853 |
Fluid overload | 35.56 | 11.18 | 66 | 250906 | 19026 | 29682480 |
Oral disorder | 35.54 | 11.18 | 94 | 250878 | 3968 | 29697538 |
Mucormycosis | 35.51 | 11.18 | 111 | 250861 | 5157 | 29696349 |
Akathisia | 35.41 | 11.18 | 4 | 250968 | 5900 | 29695606 |
Blood stem cell transplant failure | 35.38 | 11.18 | 29 | 250943 | 396 | 29701110 |
Lymphocyte count decreased | 35.38 | 11.18 | 66 | 250906 | 18989 | 29682517 |
Neutropenia | 34.92 | 11.18 | 1362 | 249610 | 127178 | 29574328 |
Progressive multifocal leukoencephalopathy | 34.91 | 11.18 | 159 | 250813 | 8854 | 29692652 |
Colitis | 34.64 | 11.18 | 403 | 250569 | 30417 | 29671089 |
Chronic obstructive pulmonary disease | 34.62 | 11.18 | 235 | 250737 | 45891 | 29655615 |
Hiccups | 34.42 | 11.18 | 18 | 250954 | 9416 | 29692090 |
Neuropathy peripheral | 34.39 | 11.18 | 401 | 250571 | 70074 | 29631432 |
Epstein-Barr virus infection reactivation | 34.21 | 11.18 | 23 | 250949 | 227 | 29701279 |
Neutrophil count increased | 34.17 | 11.18 | 47 | 250925 | 15276 | 29686230 |
Infusion related reaction | 34.11 | 11.18 | 503 | 250469 | 40061 | 29661445 |
Pneumonia cryptococcal | 34.09 | 11.18 | 36 | 250936 | 690 | 29700816 |
Obliterative bronchiolitis | 34.07 | 11.18 | 46 | 250926 | 1152 | 29700354 |
Contraindication to medical treatment | 34.04 | 11.18 | 30 | 250942 | 455 | 29701051 |
Facial paralysis | 34.02 | 11.18 | 168 | 250804 | 9675 | 29691831 |
Haematoma | 33.93 | 11.18 | 96 | 250876 | 23857 | 29677649 |
Heart rate increased | 33.90 | 11.18 | 188 | 250784 | 38533 | 29662973 |
Hypoxia | 33.86 | 11.18 | 248 | 250724 | 47606 | 29653900 |
Hepatic fibrosis | 33.54 | 11.18 | 85 | 250887 | 3495 | 29698011 |
Ill-defined disorder | 33.47 | 11.18 | 175 | 250797 | 10309 | 29691197 |
Hepatitis C | 33.13 | 11.18 | 37 | 250935 | 13168 | 29688338 |
Failure to thrive | 33.08 | 11.18 | 13 | 250959 | 8041 | 29693465 |
Gingivitis ulcerative | 33.08 | 11.18 | 14 | 250958 | 46 | 29701460 |
Right ventricular failure | 32.96 | 11.18 | 13 | 250959 | 8023 | 29693483 |
Staphylococcal sepsis | 32.81 | 11.18 | 162 | 250810 | 9329 | 29692177 |
Palmar-plantar erythrodysaesthesia syndrome | 32.77 | 11.18 | 46 | 250926 | 14824 | 29686682 |
Hepatic cirrhosis | 32.69 | 11.18 | 238 | 250734 | 15761 | 29685745 |
Chromaturia | 32.48 | 11.18 | 41 | 250931 | 13824 | 29687682 |
Myelitis transverse | 32.48 | 11.18 | 41 | 250931 | 959 | 29700547 |
Device occlusion | 32.41 | 11.18 | 6 | 250966 | 6114 | 29695392 |
Venous injury | 32.37 | 11.18 | 23 | 250949 | 250 | 29701256 |
End stage renal disease | 32.23 | 11.18 | 11 | 250961 | 7424 | 29694082 |
Varicella zoster virus infection | 32.04 | 11.18 | 46 | 250926 | 1222 | 29700284 |
Cerebral venous sinus thrombosis | 32.03 | 11.18 | 24 | 250948 | 285 | 29701221 |
Cutaneous lymphoma | 31.94 | 11.18 | 15 | 250957 | 67 | 29701439 |
Faeces discoloured | 31.89 | 11.18 | 42 | 250930 | 13904 | 29687602 |
Scleroderma | 31.87 | 11.18 | 47 | 250925 | 1280 | 29700226 |
Cytomegalovirus infection reactivation | 31.86 | 11.18 | 54 | 250918 | 1661 | 29699845 |
Disturbance in attention | 31.85 | 11.18 | 88 | 250884 | 22041 | 29679465 |
Hepatitis cholestatic | 31.85 | 11.18 | 13 | 250959 | 7859 | 29693647 |
Faecal calprotectin increased | 31.78 | 11.18 | 44 | 250928 | 1129 | 29700377 |
Engraft failure | 31.75 | 11.18 | 28 | 250944 | 425 | 29701081 |
Intervertebral discitis | 31.54 | 11.18 | 54 | 250918 | 1675 | 29699831 |
Tardive dyskinesia | 31.43 | 11.18 | 3 | 250969 | 5054 | 29696452 |
Osteosclerosis | 31.35 | 11.18 | 44 | 250928 | 1144 | 29700362 |
Bursitis infective | 31.20 | 11.18 | 29 | 250943 | 473 | 29701033 |
Memory impairment | 31.19 | 11.18 | 183 | 250789 | 36991 | 29664515 |
Mucosal toxicity | 31.08 | 11.18 | 20 | 250952 | 182 | 29701324 |
Lung adenocarcinoma | 31.05 | 11.18 | 90 | 250882 | 4009 | 29697497 |
Herpes simplex oesophagitis | 30.95 | 11.18 | 18 | 250954 | 134 | 29701372 |
Frequent bowel movements | 30.88 | 11.18 | 146 | 250826 | 8259 | 29693247 |
Oropharyngeal pain | 30.87 | 11.18 | 370 | 250602 | 28126 | 29673380 |
Troponin increased | 30.72 | 11.18 | 18 | 250954 | 8839 | 29692667 |
Hyperhidrosis | 30.35 | 11.18 | 388 | 250584 | 66702 | 29634804 |
Hyperbilirubinaemia | 30.14 | 11.18 | 244 | 250728 | 16698 | 29684808 |
Medial tibial stress syndrome | 30.12 | 11.18 | 10 | 250962 | 12 | 29701494 |
Speech disorder | 29.96 | 11.18 | 105 | 250867 | 24407 | 29677099 |
Withdrawal syndrome | 29.93 | 11.18 | 30 | 250942 | 11220 | 29690286 |
Drug tolerance decreased | 29.87 | 11.18 | 42 | 250930 | 1094 | 29700412 |
Salivary hypersecretion | 29.80 | 11.18 | 13 | 250959 | 7553 | 29693953 |
Myelosuppression | 29.74 | 11.18 | 131 | 250841 | 7191 | 29694315 |
Blood calcium decreased | 29.69 | 11.18 | 22 | 250950 | 9540 | 29691966 |
Spondyloarthropathy | 29.62 | 11.18 | 27 | 250945 | 429 | 29701077 |
Sinusitis | 29.42 | 11.18 | 417 | 250555 | 32928 | 29668578 |
Aspiration | 29.39 | 11.18 | 27 | 250945 | 10524 | 29690982 |
Cytotoxic oedema | 29.34 | 11.18 | 19 | 250953 | 175 | 29701331 |
Mucocutaneous leishmaniasis | 29.18 | 11.18 | 13 | 250959 | 50 | 29701456 |
Tropical infectious disease | 29.15 | 11.18 | 12 | 250960 | 36 | 29701470 |
Pseudostroke | 29.15 | 11.18 | 12 | 250960 | 36 | 29701470 |
Pericarditis | 29.11 | 11.18 | 146 | 250826 | 8460 | 29693046 |
Gastric disorder | 28.98 | 11.18 | 169 | 250803 | 10374 | 29691132 |
Ileal stenosis | 28.97 | 11.18 | 42 | 250930 | 1126 | 29700380 |
Tubulointerstitial nephritis | 28.97 | 11.18 | 67 | 250905 | 17824 | 29683682 |
Myelitis | 28.92 | 11.18 | 32 | 250940 | 648 | 29700858 |
Toxic leukoencephalopathy | 28.88 | 11.18 | 20 | 250952 | 208 | 29701298 |
Abnormal dreams | 28.85 | 11.18 | 16 | 250956 | 8099 | 29693407 |
Poisoning deliberate | 28.79 | 11.18 | 7 | 250965 | 5897 | 29695609 |
Poor venous access | 28.78 | 11.18 | 64 | 250908 | 2416 | 29699090 |
Cytomegalovirus test positive | 28.55 | 11.18 | 81 | 250891 | 3564 | 29697942 |
Hallucination, auditory | 28.53 | 11.18 | 24 | 250948 | 9765 | 29691741 |
Mania | 28.50 | 11.18 | 21 | 250951 | 9133 | 29692373 |
Myelodysplastic syndrome | 28.46 | 11.18 | 261 | 250711 | 18517 | 29682989 |
Gliosis | 28.42 | 11.18 | 18 | 250954 | 159 | 29701347 |
Drug ineffective for unapproved indication | 28.37 | 11.18 | 172 | 250800 | 10708 | 29690798 |
Oesophageal stenosis | 28.30 | 11.18 | 49 | 250923 | 1534 | 29699972 |
Therapeutic response shortened | 28.20 | 11.18 | 80 | 250892 | 3520 | 29697986 |
Emotional distress | 28.05 | 11.18 | 56 | 250916 | 15709 | 29685797 |
Skin mass | 27.88 | 11.18 | 78 | 250894 | 3404 | 29698102 |
Tricuspid valve incompetence | 27.88 | 11.18 | 19 | 250953 | 8604 | 29692902 |
Exposure during pregnancy | 27.87 | 11.18 | 22 | 250950 | 9239 | 29692267 |
Presyncope | 27.75 | 11.18 | 58 | 250914 | 15998 | 29685508 |
Infectious pleural effusion | 27.74 | 11.18 | 56 | 250916 | 1974 | 29699532 |
Iron deficiency anaemia | 27.72 | 11.18 | 21 | 250951 | 9003 | 29692503 |
Septic arthritis staphylococcal | 27.63 | 11.18 | 26 | 250946 | 431 | 29701075 |
Product substitution issue | 27.57 | 11.18 | 26 | 250946 | 10009 | 29691497 |
Tenderness | 27.31 | 11.18 | 108 | 250864 | 5647 | 29695859 |
Sweat gland tumour | 27.18 | 11.18 | 25 | 250947 | 402 | 29701104 |
Epstein-Barr virus associated lymphoma | 27.13 | 11.18 | 28 | 250944 | 522 | 29700984 |
Tooth loss | 27.09 | 11.18 | 84 | 250888 | 3885 | 29697621 |
T-cell type acute leukaemia | 26.99 | 11.18 | 18 | 250954 | 175 | 29701331 |
Bicytopenia | 26.99 | 11.18 | 51 | 250921 | 1711 | 29699795 |
Gastrointestinal toxicity | 26.97 | 11.18 | 55 | 250917 | 1953 | 29699553 |
Prothrombin time prolonged | 26.88 | 11.18 | 23 | 250949 | 9280 | 29692226 |
Wrong technique in product usage process | 26.87 | 11.18 | 152 | 250820 | 31003 | 29670503 |
Osteosarcoma | 26.74 | 11.18 | 18 | 250954 | 178 | 29701328 |
Lipoma | 26.64 | 11.18 | 46 | 250926 | 1437 | 29700069 |
Premature baby | 26.63 | 11.18 | 63 | 250909 | 16628 | 29684878 |
Intestinal sepsis | 26.59 | 11.18 | 25 | 250947 | 414 | 29701092 |
Angioimmunoblastic T-cell lymphoma stage III | 26.53 | 11.18 | 7 | 250965 | 0 | 29701506 |
Serum procollagen type III N-terminal propeptide increased | 26.53 | 11.18 | 13 | 250959 | 65 | 29701441 |
Mycobacterium marinum infection | 26.52 | 11.18 | 20 | 250952 | 240 | 29701266 |
Symptom recurrence | 26.48 | 11.18 | 17 | 250955 | 154 | 29701352 |
Meningitis haemophilus | 26.48 | 11.18 | 8 | 250964 | 5 | 29701501 |
Bladder cancer | 26.40 | 11.18 | 148 | 250824 | 8954 | 29692552 |
T-cell lymphoma | 26.38 | 11.18 | 36 | 250936 | 911 | 29700595 |
Impaired healing | 26.31 | 11.18 | 208 | 250764 | 14132 | 29687374 |
Meningitis listeria | 26.25 | 11.18 | 23 | 250949 | 346 | 29701160 |
Second primary malignancy | 26.03 | 11.18 | 114 | 250858 | 6242 | 29695264 |
Spondylitis | 25.94 | 11.18 | 39 | 250933 | 1081 | 29700425 |
Acute myelomonocytic leukaemia | 25.86 | 11.18 | 16 | 250956 | 135 | 29701371 |
Asthma | 25.82 | 11.18 | 187 | 250785 | 35987 | 29665519 |
Chemotherapeutic drug level above therapeutic | 25.79 | 11.18 | 9 | 250963 | 14 | 29701492 |
Oral mucosa erosion | 25.72 | 11.18 | 33 | 250939 | 785 | 29700721 |
Aspergillus infection | 25.70 | 11.18 | 160 | 250812 | 10054 | 29691452 |
Acidosis | 25.69 | 11.18 | 29 | 250943 | 10272 | 29691234 |
Vertigo | 25.67 | 11.18 | 100 | 250872 | 22535 | 29678971 |
Atrial septal defect | 25.64 | 11.18 | 12 | 250960 | 6689 | 29694817 |
Leukopenia | 25.63 | 11.18 | 634 | 250338 | 55525 | 29645981 |
Glycosylated haemoglobin increased | 25.60 | 11.18 | 25 | 250947 | 9466 | 29692040 |
Lethargy | 25.53 | 11.18 | 210 | 250762 | 39309 | 29662197 |
Shock haemorrhagic | 25.46 | 11.18 | 27 | 250945 | 9838 | 29691668 |
Diffuse large B-cell lymphoma recurrent | 25.42 | 11.18 | 55 | 250917 | 2037 | 29699469 |
Dysuria | 25.30 | 11.18 | 100 | 250872 | 22441 | 29679065 |
Dry mouth | 25.25 | 11.18 | 102 | 250870 | 22748 | 29678758 |
Prescribed underdose | 25.21 | 11.18 | 17 | 250955 | 7742 | 29693764 |
Pyopneumothorax | 25.14 | 11.18 | 12 | 250960 | 56 | 29701450 |
Aspiration bone marrow abnormal | 24.89 | 11.18 | 14 | 250958 | 97 | 29701409 |
Bundle branch block right | 24.87 | 11.18 | 14 | 250958 | 7028 | 29694478 |
Incorrect disposal of product | 24.86 | 11.18 | 19 | 250953 | 233 | 29701273 |
Alcohol abuse | 24.85 | 11.18 | 7 | 250965 | 5346 | 29696160 |
Cerebral venous thrombosis | 24.85 | 11.18 | 28 | 250944 | 579 | 29700927 |
Therapeutic product effect delayed | 24.81 | 11.18 | 38 | 250934 | 1071 | 29700435 |
Ankle deformity | 24.72 | 11.18 | 18 | 250954 | 204 | 29701302 |
Lung cancer metastatic | 24.71 | 11.18 | 61 | 250911 | 2467 | 29699039 |
Pruritus | 24.70 | 11.18 | 778 | 250194 | 117426 | 29584080 |
Thinking abnormal | 24.56 | 11.18 | 7 | 250965 | 5304 | 29696202 |
Encephalitis | 24.53 | 11.18 | 113 | 250859 | 6323 | 29695183 |
Supraventricular tachycardia | 24.46 | 11.18 | 30 | 250942 | 10242 | 29691264 |
Priapism | 24.38 | 11.18 | 5 | 250967 | 4738 | 29696768 |
Axial spondyloarthritis | 24.30 | 11.18 | 16 | 250956 | 152 | 29701354 |
Squamous cell carcinoma of the tongue | 24.30 | 11.18 | 17 | 250955 | 180 | 29701326 |
Rheumatoid factor increased | 24.23 | 11.18 | 25 | 250947 | 466 | 29701040 |
Acute lymphocytic leukaemia refractory | 24.21 | 11.18 | 14 | 250958 | 103 | 29701403 |
Acute monocytic leukaemia | 24.16 | 11.18 | 22 | 250950 | 349 | 29701157 |
Subdural hygroma | 24.12 | 11.18 | 21 | 250951 | 313 | 29701193 |
Escherichia sepsis | 24.07 | 11.18 | 81 | 250891 | 3913 | 29697593 |
Complications of transplanted kidney | 24.05 | 11.18 | 3 | 250969 | 4098 | 29697408 |
Hepatic function abnormal | 24.00 | 11.18 | 489 | 250483 | 41456 | 29660050 |
Hypoxic-ischaemic encephalopathy | 23.97 | 11.18 | 5 | 250967 | 4682 | 29696824 |
Nephrolithiasis | 23.82 | 11.18 | 315 | 250657 | 24495 | 29677011 |
Human rhinovirus test positive | 23.79 | 11.18 | 16 | 250956 | 158 | 29701348 |
Osteosarcoma recurrent | 23.75 | 11.18 | 9 | 250963 | 20 | 29701486 |
Pneumonia cytomegaloviral | 23.75 | 11.18 | 64 | 250908 | 2732 | 29698774 |
Tongue disorder | 23.74 | 11.18 | 85 | 250887 | 4237 | 29697269 |
Blood fibrinogen decreased | 23.71 | 11.18 | 35 | 250937 | 954 | 29700552 |
Atrioventricular block first degree | 23.66 | 11.18 | 9 | 250963 | 5679 | 29695827 |
Bone sarcoma | 23.60 | 11.18 | 13 | 250959 | 86 | 29701420 |
Disseminated aspergillosis | 23.60 | 11.18 | 13 | 250959 | 86 | 29701420 |
Urticaria | 23.60 | 11.18 | 612 | 250360 | 53994 | 29647512 |
Pleuropericarditis | 23.54 | 11.18 | 17 | 250955 | 190 | 29701316 |
Skin erosion | 23.53 | 11.18 | 48 | 250924 | 1705 | 29699801 |
Sudden death | 23.52 | 11.18 | 60 | 250912 | 15432 | 29686074 |
Fine motor skill dysfunction | 23.51 | 11.18 | 38 | 250934 | 1123 | 29700383 |
Osteopenia | 23.51 | 11.18 | 89 | 250883 | 4559 | 29696947 |
Actinomycotic pulmonary infection | 23.50 | 11.18 | 8 | 250964 | 11 | 29701495 |
Macule | 23.45 | 11.18 | 33 | 250939 | 860 | 29700646 |
Shock | 23.43 | 11.18 | 105 | 250867 | 22754 | 29678752 |
Ventricular hypertrophy | 23.43 | 11.18 | 6 | 250966 | 4881 | 29696625 |
Angina unstable | 23.42 | 11.18 | 42 | 250930 | 12268 | 29689238 |
Low density lipoprotein increased | 23.40 | 11.18 | 3 | 250969 | 4013 | 29697493 |
Extradural abscess | 23.36 | 11.18 | 28 | 250944 | 620 | 29700886 |
Joint warmth | 23.27 | 11.18 | 18 | 250954 | 225 | 29701281 |
Pneumocystis jirovecii infection | 23.22 | 11.18 | 41 | 250931 | 1304 | 29700202 |
Injection site papule | 23.20 | 11.18 | 20 | 250952 | 294 | 29701212 |
Neck pain | 23.15 | 11.18 | 273 | 250699 | 20671 | 29680835 |
Blood loss anaemia | 23.10 | 11.18 | 18 | 250954 | 7609 | 29693897 |
Hypophosphataemia | 23.08 | 11.18 | 21 | 250951 | 8224 | 29693282 |
Neutropenic colitis | 23.07 | 11.18 | 55 | 250917 | 2175 | 29699331 |
Pyoderma gangrenosum | 23.04 | 11.18 | 36 | 250936 | 1033 | 29700473 |
Hepatic enzyme abnormal | 23.00 | 11.18 | 55 | 250917 | 2179 | 29699327 |
Anger | 22.95 | 11.18 | 36 | 250936 | 11084 | 29690422 |
Empyema | 22.89 | 11.18 | 64 | 250908 | 2792 | 29698714 |
Iritis | 22.88 | 11.18 | 40 | 250932 | 1262 | 29700244 |
Blood count abnormal | 22.85 | 11.18 | 39 | 250933 | 11613 | 29689893 |
Bronchospasm | 22.76 | 11.18 | 32 | 250940 | 10306 | 29691200 |
Paraplegia | 22.69 | 11.18 | 61 | 250911 | 2600 | 29698906 |
Cerebral thrombosis | 22.66 | 11.18 | 32 | 250940 | 837 | 29700669 |
Cheilitis | 22.65 | 11.18 | 55 | 250917 | 2201 | 29699305 |
Bronchial carcinoma | 22.64 | 11.18 | 33 | 250939 | 889 | 29700617 |
Granulomatous pneumonitis | 22.62 | 11.18 | 9 | 250963 | 24 | 29701482 |
Limb deformity | 22.61 | 11.18 | 24 | 250948 | 463 | 29701043 |
Ageusia | 22.55 | 11.18 | 25 | 250947 | 8928 | 29692578 |
Granulocytopenia | 22.54 | 11.18 | 12 | 250960 | 6214 | 29695292 |
Refractoriness to platelet transfusion | 22.54 | 11.18 | 10 | 250962 | 38 | 29701468 |
Chest discomfort | 22.48 | 11.18 | 258 | 250714 | 45222 | 29656284 |
Stenotrophomonas infection | 22.43 | 11.18 | 45 | 250927 | 1579 | 29699927 |
Hodgkin's disease | 22.37 | 11.18 | 33 | 250939 | 899 | 29700607 |
Joint tuberculosis | 22.34 | 11.18 | 10 | 250962 | 39 | 29701467 |
Bone marrow transplant rejection | 22.29 | 11.18 | 16 | 250956 | 177 | 29701329 |
Hyperthyroidism | 22.23 | 11.18 | 21 | 250951 | 8077 | 29693429 |
Transaminases increased | 22.18 | 11.18 | 297 | 250675 | 23160 | 29678346 |
Hypogammaglobulinaemia | 22.12 | 11.18 | 95 | 250877 | 5157 | 29696349 |
Dyspnoea exertional | 22.10 | 11.18 | 190 | 250782 | 35240 | 29666266 |
Atrioventricular block complete | 22.10 | 11.18 | 23 | 250949 | 8454 | 29693052 |
Inflammatory bowel disease | 22.06 | 11.18 | 55 | 250917 | 2238 | 29699268 |
Facial paresis | 22.00 | 11.18 | 63 | 250909 | 2787 | 29698719 |
Swollen joint count increased | 21.98 | 11.18 | 11 | 250961 | 58 | 29701448 |
Ventricular extrasystoles | 21.96 | 11.18 | 39 | 250933 | 11435 | 29690071 |
Ventricular fibrillation | 21.94 | 11.18 | 60 | 250912 | 15078 | 29686428 |
Flatulence | 21.92 | 11.18 | 78 | 250894 | 18051 | 29683455 |
Interstitial lung disease | 21.91 | 11.18 | 660 | 250312 | 59537 | 29641969 |
Tuberculous pleurisy | 21.85 | 11.18 | 21 | 250951 | 358 | 29701148 |
Psychomotor hyperactivity | 21.80 | 11.18 | 22 | 250950 | 8202 | 29693304 |
Angioimmunoblastic T-cell lymphoma stage IV | 21.74 | 11.18 | 7 | 250965 | 7 | 29701499 |
Hyperuricaemia | 21.71 | 11.18 | 18 | 250954 | 7376 | 29694130 |
JC virus infection | 21.68 | 11.18 | 47 | 250925 | 1743 | 29699763 |
Hypothermia | 21.68 | 11.18 | 29 | 250943 | 9538 | 29691968 |
Abdominal pain upper | 21.65 | 11.18 | 381 | 250591 | 62170 | 29639336 |
Terminal state | 21.64 | 11.18 | 73 | 250899 | 3531 | 29697975 |
White blood cell count decreased | 21.50 | 11.18 | 537 | 250435 | 83410 | 29618096 |
Bladder transitional cell carcinoma recurrent | 21.48 | 11.18 | 13 | 250959 | 105 | 29701401 |
Rheumatoid vasculitis | 21.43 | 11.18 | 17 | 250955 | 221 | 29701285 |
Non-alcoholic steatohepatitis | 21.42 | 11.18 | 29 | 250943 | 728 | 29700778 |
Synovial disorder | 21.38 | 11.18 | 13 | 250959 | 106 | 29701400 |
Glioblastoma multiforme | 21.36 | 11.18 | 31 | 250941 | 832 | 29700674 |
Ependymoma malignant | 21.35 | 11.18 | 8 | 250964 | 17 | 29701489 |
Cutaneous symptom | 21.31 | 11.18 | 18 | 250954 | 257 | 29701249 |
Chronic graft versus host disease in intestine | 21.30 | 11.18 | 17 | 250955 | 223 | 29701283 |
Minimal residual disease | 21.30 | 11.18 | 17 | 250955 | 223 | 29701283 |
Acute respiratory failure | 21.28 | 11.18 | 128 | 250844 | 25722 | 29675784 |
Blood cholesterol increased | 21.21 | 11.18 | 72 | 250900 | 16898 | 29684608 |
Epstein-Barr virus antigen positive | 21.17 | 11.18 | 9 | 250963 | 30 | 29701476 |
Antithrombin III decreased | 21.16 | 11.18 | 21 | 250951 | 373 | 29701133 |
Carcinoma in situ of skin | 21.12 | 11.18 | 12 | 250960 | 85 | 29701421 |
Juvenile melanoma benign | 21.12 | 11.18 | 11 | 250961 | 64 | 29701442 |
Meningitis chemical | 21.12 | 11.18 | 11 | 250961 | 64 | 29701442 |
Tonsil cancer | 21.10 | 11.18 | 29 | 250943 | 739 | 29700767 |
Oral surgery | 21.09 | 11.18 | 25 | 250947 | 547 | 29700959 |
Atrioventricular block | 21.05 | 11.18 | 18 | 250954 | 7264 | 29694242 |
Infective myositis | 21.05 | 11.18 | 8 | 250964 | 18 | 29701488 |
No adverse event | 21.03 | 11.18 | 75 | 250897 | 17344 | 29684162 |
C-reactive protein decreased | 20.93 | 11.18 | 43 | 250929 | 1535 | 29699971 |
Pulmonary arteriopathy | 20.84 | 11.18 | 11 | 250961 | 66 | 29701440 |
Micrognathia | 20.75 | 11.18 | 18 | 250954 | 267 | 29701239 |
Varicella | 20.66 | 11.18 | 42 | 250930 | 1488 | 29700018 |
Gout | 20.61 | 11.18 | 75 | 250897 | 17240 | 29684266 |
Dermatitis acneiform | 20.54 | 11.18 | 11 | 250961 | 5678 | 29695828 |
Leishmaniasis | 20.53 | 11.18 | 19 | 250953 | 308 | 29701198 |
Graft versus host disease in eye | 20.42 | 11.18 | 16 | 250956 | 204 | 29701302 |
Osteonecrosis | 20.42 | 11.18 | 216 | 250756 | 15919 | 29685587 |
Leukodystrophy | 20.34 | 11.18 | 6 | 250966 | 3 | 29701503 |
Meningitis staphylococcal | 20.32 | 11.18 | 11 | 250961 | 70 | 29701436 |
Muscle spasticity | 20.30 | 11.18 | 9 | 250963 | 5179 | 29696327 |
Bronchopulmonary aspergillosis | 20.29 | 11.18 | 174 | 250798 | 12110 | 29689396 |
Thyroid cancer | 20.27 | 11.18 | 38 | 250934 | 1267 | 29700239 |
Acute coronary syndrome | 20.27 | 11.18 | 53 | 250919 | 13520 | 29687986 |
Pneumonia fungal | 20.24 | 11.18 | 96 | 250876 | 5437 | 29696069 |
Cardiac failure chronic | 20.22 | 11.18 | 12 | 250960 | 5851 | 29695655 |
Ischaemic cardiomyopathy | 20.19 | 11.18 | 14 | 250958 | 6283 | 29695223 |
Soft tissue swelling | 20.16 | 11.18 | 17 | 250955 | 242 | 29701264 |
Gastric haemorrhage | 20.16 | 11.18 | 30 | 250942 | 9437 | 29692069 |
Muscle swelling | 20.16 | 11.18 | 20 | 250952 | 355 | 29701151 |
West Nile viral infection | 20.09 | 11.18 | 25 | 250947 | 576 | 29700930 |
Blood alkaline phosphatase increased | 20.02 | 11.18 | 168 | 250804 | 31319 | 29670187 |
Skin dystrophy | 20.01 | 11.18 | 7 | 250965 | 11 | 29701495 |
Faecaloma | 20.01 | 11.18 | 6 | 250966 | 4399 | 29697107 |
Vasculitis | 20.00 | 11.18 | 125 | 250847 | 7865 | 29693641 |
Intestinal ischaemia | 19.99 | 11.18 | 17 | 250955 | 6880 | 29694626 |
Secondary amyloidosis | 19.94 | 11.18 | 10 | 250962 | 53 | 29701453 |
Infectious thyroiditis | 19.92 | 11.18 | 12 | 250960 | 96 | 29701410 |
Intentional product use issue | 19.92 | 11.18 | 422 | 250550 | 36018 | 29665488 |
Aphthous ulcer | 19.88 | 11.18 | 78 | 250894 | 4063 | 29697443 |
Hepatitis B virus test positive | 19.85 | 11.18 | 16 | 250956 | 213 | 29701293 |
Pachymeningitis | 19.82 | 11.18 | 12 | 250960 | 97 | 29701409 |
Adult T-cell lymphoma/leukaemia | 19.77 | 11.18 | 17 | 250955 | 249 | 29701257 |
Steatohepatitis | 19.67 | 11.18 | 19 | 250953 | 326 | 29701180 |
Keratitis | 19.56 | 11.18 | 35 | 250937 | 1125 | 29700381 |
Face oedema | 19.54 | 11.18 | 41 | 250931 | 11293 | 29690213 |
Ophthalmic herpes zoster | 19.53 | 11.18 | 26 | 250946 | 642 | 29700864 |
Alopecia | 19.46 | 11.18 | 247 | 250725 | 19028 | 29682478 |
Refusal of treatment by patient | 19.41 | 11.18 | 9 | 250963 | 5044 | 29696462 |
Stem cell transplant | 19.34 | 11.18 | 50 | 250922 | 2081 | 29699425 |
Brain natriuretic peptide increased | 19.25 | 11.18 | 5 | 250967 | 4030 | 29697476 |
Liver disorder | 19.21 | 11.18 | 353 | 250619 | 29369 | 29672137 |
Peritonitis | 19.13 | 11.18 | 103 | 250869 | 21272 | 29680234 |
Nasal cavity cancer | 19.11 | 11.18 | 13 | 250959 | 131 | 29701375 |
Iris adhesions | 19.10 | 11.18 | 15 | 250957 | 192 | 29701314 |
Acute myeloid leukaemia recurrent | 19.09 | 11.18 | 41 | 250931 | 1511 | 29699995 |
Pemphigoid | 18.98 | 11.18 | 21 | 250951 | 7507 | 29693999 |
Cerebral infarction | 18.98 | 11.18 | 136 | 250836 | 26237 | 29675269 |
Lung neoplasm | 18.97 | 11.18 | 82 | 250890 | 4464 | 29697042 |
Epstein-Barr virus test positive | 18.96 | 11.18 | 23 | 250949 | 516 | 29700990 |
Heavy chain disease | 18.95 | 11.18 | 5 | 250967 | 0 | 29701506 |
Injection site rash | 18.93 | 11.18 | 69 | 250903 | 3470 | 29698036 |
Large intestinal stenosis | 18.92 | 11.18 | 36 | 250936 | 1214 | 29700292 |
Muscle haemorrhage | 18.84 | 11.18 | 4 | 250968 | 3699 | 29697807 |
Mucosal disorder | 18.82 | 11.18 | 41 | 250931 | 1526 | 29699980 |
Physical disability | 18.78 | 11.18 | 34 | 250938 | 1103 | 29700403 |
Monoclonal B-cell lymphocytosis | 18.74 | 11.18 | 8 | 250964 | 27 | 29701479 |
Salivary gland cancer | 18.74 | 11.18 | 16 | 250956 | 232 | 29701274 |
Bradyphrenia | 18.70 | 11.18 | 5 | 250967 | 3952 | 29697554 |
Morphoea | 18.55 | 11.18 | 13 | 250959 | 138 | 29701368 |
Crohn's disease | 18.54 | 11.18 | 79 | 250893 | 4273 | 29697233 |
Body temperature fluctuation | 18.54 | 11.18 | 36 | 250936 | 1233 | 29700273 |
Small fibre neuropathy | 18.53 | 11.18 | 8 | 250964 | 28 | 29701478 |
Product complaint | 18.50 | 11.18 | 13 | 250959 | 5793 | 29695713 |
Alveolitis | 18.47 | 11.18 | 43 | 250929 | 1674 | 29699832 |
Metastatic bronchial carcinoma | 18.35 | 11.18 | 15 | 250957 | 204 | 29701302 |
Synovectomy | 18.30 | 11.18 | 10 | 250962 | 65 | 29701441 |
Thymus enlargement | 18.30 | 11.18 | 10 | 250962 | 65 | 29701441 |
Burkitt's lymphoma | 18.23 | 11.18 | 14 | 250958 | 173 | 29701333 |
Muscle twitching | 18.20 | 11.18 | 25 | 250947 | 8130 | 29693376 |
Obsessive-compulsive disorder | 18.17 | 11.18 | 6 | 250966 | 4135 | 29697371 |
Nail dystrophy | 18.14 | 11.18 | 12 | 250960 | 115 | 29701391 |
Catatonia | 18.10 | 11.18 | 7 | 250965 | 4373 | 29697133 |
Meningitis tuberculous | 18.09 | 11.18 | 23 | 250949 | 542 | 29700964 |
Musculoskeletal disorder | 18.01 | 11.18 | 85 | 250887 | 4804 | 29696702 |
Thirst | 17.95 | 11.18 | 19 | 250953 | 6930 | 29694576 |
International normalised ratio decreased | 17.90 | 11.18 | 8 | 250964 | 4582 | 29696924 |
Lower respiratory tract infection | 17.87 | 11.18 | 319 | 250653 | 26395 | 29675111 |
Blood magnesium decreased | 17.84 | 11.18 | 12 | 250960 | 5471 | 29696035 |
Osteolysis | 17.81 | 11.18 | 40 | 250932 | 1520 | 29699986 |
Immune recovery uveitis | 17.77 | 11.18 | 7 | 250965 | 18 | 29701488 |
Drug dependence | 17.77 | 11.18 | 105 | 250867 | 21190 | 29680316 |
Circulatory collapse | 17.76 | 11.18 | 98 | 250874 | 20116 | 29681390 |
Rectal haemorrhage | 17.74 | 11.18 | 197 | 250775 | 34742 | 29666764 |
Medication error | 17.71 | 11.18 | 103 | 250869 | 20869 | 29680637 |
Granulomatosis with polyangiitis | 17.58 | 11.18 | 29 | 250943 | 872 | 29700634 |
Pericarditis tuberculous | 17.57 | 11.18 | 11 | 250961 | 95 | 29701411 |
Polychondritis | 17.52 | 11.18 | 13 | 250959 | 152 | 29701354 |
Sepsis | 17.49 | 11.18 | 1439 | 249533 | 144956 | 29556550 |
Autoimmune lymphoproliferative syndrome | 17.38 | 11.18 | 13 | 250959 | 154 | 29701352 |
Tooth abscess | 17.36 | 11.18 | 87 | 250885 | 5039 | 29696467 |
Somnambulism | 17.35 | 11.18 | 3 | 250969 | 3211 | 29698295 |
Cystitis escherichia | 17.33 | 11.18 | 14 | 250958 | 187 | 29701319 |
Eye infection toxoplasmal | 17.33 | 11.18 | 14 | 250958 | 187 | 29701319 |
Infective tenosynovitis | 17.33 | 11.18 | 9 | 250963 | 52 | 29701454 |
Shoulder arthroplasty | 17.32 | 11.18 | 20 | 250952 | 425 | 29701081 |
Purulent pericarditis | 17.32 | 11.18 | 6 | 250966 | 9 | 29701497 |
Cushingoid | 17.32 | 11.18 | 53 | 250919 | 2434 | 29699072 |
Spinal cord disorder | 17.30 | 11.18 | 24 | 250948 | 617 | 29700889 |
Neonatal respiratory distress syndrome | 17.28 | 11.18 | 6 | 250966 | 4006 | 29697500 |
Hemiparesis | 17.28 | 11.18 | 195 | 250777 | 14607 | 29686899 |
Altered state of consciousness | 17.27 | 11.18 | 97 | 250875 | 19822 | 29681684 |
Cerebrosclerosis | 17.25 | 11.18 | 7 | 250965 | 20 | 29701486 |
Glottis carcinoma | 17.25 | 11.18 | 7 | 250965 | 20 | 29701486 |
Rheumatic disorder | 17.24 | 11.18 | 21 | 250951 | 473 | 29701033 |
Meningitis enterococcal | 17.24 | 11.18 | 10 | 250962 | 74 | 29701432 |
Abdominal discomfort | 17.23 | 11.18 | 533 | 250439 | 48258 | 29653248 |
Mediastinal mass | 17.17 | 11.18 | 13 | 250959 | 157 | 29701349 |
Ischaemic stroke | 17.14 | 11.18 | 74 | 250898 | 16201 | 29685305 |
Palmoplantar pustulosis | 17.13 | 11.18 | 10 | 250962 | 75 | 29701431 |
Ligament calcification | 17.05 | 11.18 | 9 | 250963 | 54 | 29701452 |
Adenoviral hepatitis | 17.04 | 11.18 | 13 | 250959 | 159 | 29701347 |
Injection site pruritus | 16.93 | 11.18 | 92 | 250880 | 5500 | 29696006 |
Episcleritis | 16.92 | 11.18 | 12 | 250960 | 130 | 29701376 |
Inflammatory myofibroblastic tumour | 16.92 | 11.18 | 12 | 250960 | 130 | 29701376 |
Precursor T-lymphoblastic lymphoma/leukaemia | 16.92 | 11.18 | 10 | 250962 | 77 | 29701429 |
Haemorrhagic stroke | 16.80 | 11.18 | 16 | 250956 | 6131 | 29695375 |
Spinal pain | 16.73 | 11.18 | 78 | 250894 | 4386 | 29697120 |
Polyuria | 16.71 | 11.18 | 22 | 250950 | 7284 | 29694222 |
Labelled drug-drug interaction medication error | 16.63 | 11.18 | 40 | 250932 | 10498 | 29691008 |
Hepatitis E | 16.61 | 11.18 | 40 | 250932 | 1592 | 29699914 |
Blood glucose fluctuation | 16.61 | 11.18 | 5 | 250967 | 3656 | 29697850 |
Body temperature decreased | 16.60 | 11.18 | 138 | 250834 | 9517 | 29691989 |
Hyperfibrinogenaemia | 16.59 | 11.18 | 6 | 250966 | 11 | 29701495 |
Cystitis viral | 16.54 | 11.18 | 20 | 250952 | 447 | 29701059 |
Pollakiuria | 16.53 | 11.18 | 79 | 250893 | 16827 | 29684679 |
Exostosis | 16.53 | 11.18 | 65 | 250907 | 3390 | 29698116 |
Cardiomegaly | 16.51 | 11.18 | 64 | 250908 | 14445 | 29687061 |
Parkinsonism | 16.51 | 11.18 | 22 | 250950 | 7247 | 29694259 |
Meningoencephalitis herpetic | 16.49 | 11.18 | 26 | 250946 | 752 | 29700754 |
Activated partial thromboplastin time prolonged | 16.48 | 11.18 | 25 | 250947 | 7803 | 29693703 |
Folate deficiency | 16.45 | 11.18 | 30 | 250942 | 979 | 29700527 |
Vascular access complication | 16.45 | 11.18 | 14 | 250958 | 202 | 29701304 |
Organising pneumonia | 16.41 | 11.18 | 85 | 250887 | 4989 | 29696517 |
Strongyloidiasis | 16.34 | 11.18 | 50 | 250922 | 2296 | 29699210 |
Erythema multiforme | 16.34 | 11.18 | 26 | 250946 | 7959 | 29693547 |
Scab | 16.33 | 11.18 | 70 | 250902 | 3796 | 29697710 |
Gastroenteritis Escherichia coli | 16.33 | 11.18 | 12 | 250960 | 138 | 29701368 |
Gynaecomastia | 16.33 | 11.18 | 28 | 250944 | 8323 | 29693183 |
Amyloidosis | 16.24 | 11.18 | 47 | 250925 | 2092 | 29699414 |
Bladder neoplasm | 16.22 | 11.18 | 32 | 250940 | 1109 | 29700397 |
Nocturia | 16.14 | 11.18 | 28 | 250944 | 8284 | 29693222 |
Hepatic failure | 16.09 | 11.18 | 195 | 250777 | 33848 | 29667658 |
Quadriplegia | 16.03 | 11.18 | 38 | 250934 | 1497 | 29700009 |
Herpes simplex | 16.00 | 11.18 | 77 | 250895 | 4387 | 29697119 |
Iridocyclitis | 15.94 | 11.18 | 36 | 250936 | 1373 | 29700133 |
Small cell lung cancer | 15.94 | 11.18 | 43 | 250929 | 1837 | 29699669 |
Leukocytosis | 15.90 | 11.18 | 110 | 250862 | 21392 | 29680114 |
Blood cholesterol abnormal | 15.88 | 11.18 | 35 | 250937 | 1313 | 29700193 |
Electrocardiogram QRS complex prolonged | 15.84 | 11.18 | 8 | 250964 | 4269 | 29697237 |
Central nervous system infection | 15.84 | 11.18 | 20 | 250952 | 468 | 29701038 |
Cavernous sinus thrombosis | 15.76 | 11.18 | 11 | 250961 | 116 | 29701390 |
Anaphylactic shock | 15.75 | 11.18 | 62 | 250910 | 13931 | 29687575 |
Systemic candida | 15.73 | 11.18 | 55 | 250917 | 2709 | 29698797 |
Infective aneurysm | 15.72 | 11.18 | 18 | 250954 | 379 | 29701127 |
Meningitis aseptic | 15.72 | 11.18 | 49 | 250923 | 2273 | 29699233 |
Gastrointestinal inflammation | 15.69 | 11.18 | 57 | 250915 | 2862 | 29698644 |
Cauda equina syndrome | 15.68 | 11.18 | 18 | 250954 | 380 | 29701126 |
Thrombosis in device | 15.66 | 11.18 | 5 | 250967 | 3521 | 29697985 |
Silicosis | 15.64 | 11.18 | 6 | 250966 | 14 | 29701492 |
Dysplastic naevus syndrome | 15.64 | 11.18 | 6 | 250966 | 14 | 29701492 |
Cutaneous tuberculosis | 15.54 | 11.18 | 10 | 250962 | 91 | 29701415 |
Arthroscopy | 15.54 | 11.18 | 10 | 250962 | 91 | 29701415 |
Bladder neck operation | 15.53 | 11.18 | 5 | 250967 | 5 | 29701501 |
Sudden cardiac death | 15.50 | 11.18 | 6 | 250966 | 3746 | 29697760 |
Trichosporon infection | 15.50 | 11.18 | 23 | 250949 | 630 | 29700876 |
Mucosal necrosis | 15.47 | 11.18 | 9 | 250963 | 67 | 29701439 |
Ketoacidosis | 15.46 | 11.18 | 6 | 250966 | 3740 | 29697766 |
Hepatic candidiasis | 15.43 | 11.18 | 8 | 250964 | 46 | 29701460 |
Body height decreased | 15.38 | 11.18 | 6 | 250966 | 3728 | 29697778 |
B-cell lymphoma stage IV | 15.36 | 11.18 | 9 | 250963 | 68 | 29701438 |
Electrocardiogram abnormal | 15.34 | 11.18 | 16 | 250956 | 5876 | 29695630 |
Legionella infection | 15.32 | 11.18 | 18 | 250954 | 390 | 29701116 |
IVth nerve paralysis | 15.29 | 11.18 | 8 | 250964 | 47 | 29701459 |
Malignant melanoma stage I | 15.27 | 11.18 | 10 | 250962 | 94 | 29701412 |
Neutrophil count decreased | 15.20 | 11.18 | 257 | 250715 | 42197 | 29659309 |
Fear-related avoidance of activities | 15.16 | 11.18 | 4 | 250968 | 0 | 29701506 |
Oral toxicity | 15.16 | 11.18 | 4 | 250968 | 0 | 29701506 |
Blood testosterone decreased | 15.15 | 11.18 | 9 | 250963 | 4387 | 29697119 |
Localised infection | 15.15 | 11.18 | 179 | 250793 | 13558 | 29687948 |
CNS ventriculitis | 15.13 | 11.18 | 14 | 250958 | 227 | 29701279 |
Tinea versicolour | 15.12 | 11.18 | 12 | 250960 | 156 | 29701350 |
Post lumbar puncture syndrome | 15.12 | 11.18 | 12 | 250960 | 156 | 29701350 |
Graft versus host disease in lung | 15.08 | 11.18 | 20 | 250952 | 492 | 29701014 |
Injection site warmth | 15.06 | 11.18 | 41 | 250931 | 1761 | 29699745 |
Superior mesenteric artery syndrome | 15.05 | 11.18 | 9 | 250963 | 71 | 29701435 |
Escherichia bacteraemia | 15.03 | 11.18 | 56 | 250916 | 2846 | 29698660 |
Palindromic rheumatism | 15.03 | 11.18 | 13 | 250959 | 192 | 29701314 |
Injection site reaction | 15.03 | 11.18 | 147 | 250825 | 10613 | 29690893 |
Haematopoietic neoplasm | 15.03 | 11.18 | 8 | 250964 | 49 | 29701457 |
Meningitis | 14.98 | 11.18 | 77 | 250895 | 4505 | 29697001 |
Asphyxia | 14.97 | 11.18 | 14 | 250958 | 5411 | 29696095 |
Visual acuity reduced | 14.94 | 11.18 | 75 | 250897 | 15771 | 29685735 |
Intestinal atresia | 14.94 | 11.18 | 9 | 250963 | 72 | 29701434 |
Swelling face | 14.94 | 11.18 | 110 | 250862 | 21094 | 29680412 |
Respiratory tract infection | 14.94 | 11.18 | 197 | 250775 | 15309 | 29686197 |
Tonsillar ulcer | 14.92 | 11.18 | 13 | 250959 | 194 | 29701312 |
Mental disorder | 14.88 | 11.18 | 60 | 250912 | 13389 | 29688117 |
Splenic lesion | 14.87 | 11.18 | 11 | 250961 | 128 | 29701378 |
International normalised ratio abnormal | 14.82 | 11.18 | 4 | 250968 | 3142 | 29698364 |
Protein urine present | 14.81 | 11.18 | 11 | 250961 | 4764 | 29696742 |
Pseudomonal sepsis | 14.81 | 11.18 | 57 | 250915 | 2943 | 29698563 |
Syringe issue | 14.77 | 11.18 | 3 | 250969 | 2862 | 29698644 |
Product administration error | 14.76 | 11.18 | 66 | 250906 | 14311 | 29687195 |
Pharyngitis | 14.68 | 11.18 | 103 | 250869 | 6739 | 29694767 |
Temporal lobe epilepsy | 14.66 | 11.18 | 11 | 250961 | 131 | 29701375 |
Nail psoriasis | 14.64 | 11.18 | 8 | 250964 | 52 | 29701454 |
Testicular seminoma (pure) | 14.64 | 11.18 | 8 | 250964 | 52 | 29701454 |
Panniculitis | 14.64 | 11.18 | 26 | 250946 | 831 | 29700675 |
Coma scale abnormal | 14.62 | 11.18 | 5 | 250967 | 3371 | 29698135 |
Transfusion | 14.61 | 11.18 | 25 | 250947 | 7436 | 29694070 |
Joint abscess | 14.60 | 11.18 | 10 | 250962 | 102 | 29701404 |
Intracranial pressure increased | 14.60 | 11.18 | 63 | 250909 | 3427 | 29698079 |
Intestinal stenosis | 14.60 | 11.18 | 42 | 250930 | 1863 | 29699643 |
Diverticular perforation | 14.58 | 11.18 | 59 | 250913 | 3118 | 29698388 |
Pharyngeal inflammation | 14.54 | 11.18 | 16 | 250956 | 322 | 29701184 |
Inflammatory pain | 14.52 | 11.18 | 8 | 250964 | 53 | 29701453 |
Extranodal marginal zone B-cell lymphoma (MALT type) | 14.51 | 11.18 | 12 | 250960 | 166 | 29701340 |
Euphoric mood | 14.48 | 11.18 | 9 | 250963 | 4281 | 29697225 |
Coccidioidomycosis | 14.47 | 11.18 | 22 | 250950 | 616 | 29700890 |
Adverse reaction | 14.47 | 11.18 | 55 | 250917 | 2823 | 29698683 |
Crystal nephropathy | 14.45 | 11.18 | 17 | 250955 | 369 | 29701137 |
Hepatosplenic candidiasis | 14.39 | 11.18 | 13 | 250959 | 204 | 29701302 |
Post procedural infection | 14.38 | 11.18 | 76 | 250896 | 4496 | 29697010 |
Anal squamous cell carcinoma | 14.35 | 11.18 | 9 | 250963 | 78 | 29701428 |
Encephalitis Japanese B | 14.34 | 11.18 | 6 | 250966 | 19 | 29701487 |
Spinal cord oedema | 14.34 | 11.18 | 12 | 250960 | 169 | 29701337 |
Body mass index abnormal | 14.26 | 11.18 | 9 | 250963 | 79 | 29701427 |
Tongue neoplasm | 14.24 | 11.18 | 5 | 250967 | 8 | 29701498 |
Cytopenia | 14.20 | 11.18 | 118 | 250854 | 8138 | 29693368 |
Mucosal ulceration | 14.18 | 11.18 | 26 | 250946 | 852 | 29700654 |
Bursa disorder | 14.17 | 11.18 | 12 | 250960 | 172 | 29701334 |
Impaired quality of life | 14.16 | 11.18 | 36 | 250936 | 1483 | 29700023 |
Injection site irritation | 14.14 | 11.18 | 28 | 250944 | 973 | 29700533 |
Osteomyelitis salmonella | 14.13 | 11.18 | 7 | 250965 | 36 | 29701470 |
Myocardial ischaemia | 14.12 | 11.18 | 86 | 250886 | 17231 | 29684275 |
Abscess sterile | 14.11 | 11.18 | 6 | 250966 | 20 | 29701486 |
Chronic actinic dermatitis | 14.11 | 11.18 | 6 | 250966 | 20 | 29701486 |
Brain abscess | 14.11 | 11.18 | 52 | 250920 | 2629 | 29698877 |
Escherichia infection | 14.09 | 11.18 | 97 | 250875 | 6308 | 29695198 |
Skin infection | 14.08 | 11.18 | 94 | 250878 | 6050 | 29695456 |
Staphylococcal bacteraemia | 14.01 | 11.18 | 101 | 250871 | 6667 | 29694839 |
Lip swelling | 14.01 | 11.18 | 57 | 250915 | 12687 | 29688819 |
Anal inflammation | 14.01 | 11.18 | 16 | 250956 | 336 | 29701170 |
Cartilage injury | 14.00 | 11.18 | 18 | 250954 | 429 | 29701077 |
Pulmonary nocardiosis | 13.99 | 11.18 | 17 | 250955 | 382 | 29701124 |
Hepatocellular carcinoma | 13.99 | 11.18 | 38 | 250934 | 9572 | 29691934 |
Prostate infection | 13.98 | 11.18 | 23 | 250949 | 690 | 29700816 |
Acute pulmonary oedema | 13.97 | 11.18 | 26 | 250946 | 7489 | 29694017 |
Granuloma | 13.97 | 11.18 | 48 | 250924 | 2344 | 29699162 |
Respiratory acidosis | 13.93 | 11.18 | 9 | 250963 | 4193 | 29697313 |
Subcutaneous abscess | 13.92 | 11.18 | 62 | 250910 | 3419 | 29698087 |
Bronchoalveolar lavage abnormal | 13.89 | 11.18 | 9 | 250963 | 83 | 29701423 |
Human herpesvirus 6 infection | 13.89 | 11.18 | 42 | 250930 | 1916 | 29699590 |
CSF myelin basic protein increased | 13.88 | 11.18 | 5 | 250967 | 9 | 29701497 |
Lymphopenia | 13.85 | 11.18 | 170 | 250802 | 12993 | 29688513 |
Cerebral toxoplasmosis | 13.84 | 11.18 | 35 | 250937 | 1437 | 29700069 |
Neurological decompensation | 13.84 | 11.18 | 47 | 250925 | 2281 | 29699225 |
Endocarditis bacterial | 13.83 | 11.18 | 25 | 250947 | 810 | 29700696 |
Coordination abnormal | 13.83 | 11.18 | 25 | 250947 | 7280 | 29694226 |
Spinal cord abscess | 13.79 | 11.18 | 13 | 250959 | 216 | 29701290 |
Renal failure | 13.78 | 11.18 | 913 | 250059 | 128053 | 29573453 |
Urine output decreased | 13.77 | 11.18 | 39 | 250933 | 9690 | 29691816 |
Transplant rejection | 13.71 | 11.18 | 36 | 250936 | 9170 | 29692336 |
Renal cell carcinoma | 13.69 | 11.18 | 89 | 250883 | 5677 | 29695829 |
HLA-B*27 positive | 13.68 | 11.18 | 6 | 250966 | 22 | 29701484 |
Meningitis viral | 13.67 | 11.18 | 23 | 250949 | 703 | 29700803 |
Nephrogenic systemic fibrosis | 13.65 | 11.18 | 10 | 250962 | 4361 | 29697145 |
Bone abscess | 13.62 | 11.18 | 11 | 250961 | 147 | 29701359 |
Diffuse large B-cell lymphoma stage III | 13.60 | 11.18 | 8 | 250964 | 61 | 29701445 |
Hyperlipidaemia | 13.59 | 11.18 | 65 | 250907 | 13842 | 29687664 |
Solar urticaria | 13.54 | 11.18 | 5 | 250967 | 10 | 29701496 |
Oropharyngitis fungal | 13.54 | 11.18 | 5 | 250967 | 10 | 29701496 |
Meningitis noninfective | 13.54 | 11.18 | 5 | 250967 | 10 | 29701496 |
Oesophageal squamous cell carcinoma | 13.53 | 11.18 | 16 | 250956 | 349 | 29701157 |
Rebound effect | 13.53 | 11.18 | 36 | 250936 | 1525 | 29699981 |
Double stranded DNULL antibody | 13.48 | 11.18 | 6 | 250966 | 23 | 29701483 |
Restless legs syndrome | 13.48 | 11.18 | 23 | 250949 | 6849 | 29694657 |
Stupor | 13.46 | 11.18 | 4 | 250968 | 2949 | 29698557 |
Intestinal fibrosis | 13.45 | 11.18 | 9 | 250963 | 88 | 29701418 |
Hypothyroidism | 13.45 | 11.18 | 72 | 250900 | 14891 | 29686615 |
Chronic graft versus host disease in liver | 13.44 | 11.18 | 14 | 250958 | 264 | 29701242 |
VIth nerve paralysis | 13.42 | 11.18 | 23 | 250949 | 714 | 29700792 |
Nervousness | 13.42 | 11.18 | 52 | 250920 | 11736 | 29689770 |
Azotaemia | 13.41 | 11.18 | 13 | 250959 | 4939 | 29696567 |
Gallbladder oedema | 13.40 | 11.18 | 12 | 250960 | 186 | 29701320 |
Malignant melanoma in situ | 13.37 | 11.18 | 27 | 250945 | 952 | 29700554 |
Diffuse large B-cell lymphoma stage IV | 13.37 | 11.18 | 13 | 250959 | 225 | 29701281 |
Ankle operation | 13.37 | 11.18 | 13 | 250959 | 225 | 29701281 |
Investigation abnormal | 13.36 | 11.18 | 16 | 250956 | 354 | 29701152 |
Atypical mycobacterial infection | 13.36 | 11.18 | 24 | 250948 | 774 | 29700732 |
Dermatitis psoriasiform | 13.34 | 11.18 | 30 | 250942 | 1141 | 29700365 |
Bacterial infection | 13.33 | 11.18 | 163 | 250809 | 12447 | 29689059 |
Myeloid leukaemia | 13.32 | 11.18 | 16 | 250956 | 355 | 29701151 |
Pneumonitis chemical | 13.31 | 11.18 | 11 | 250961 | 152 | 29701354 |
Cardiac murmur | 13.29 | 11.18 | 23 | 250949 | 6811 | 29694695 |
Left ventricular hypertrophy | 13.27 | 11.18 | 20 | 250952 | 6258 | 29695248 |
Personality change due to a general medical condition | 13.26 | 11.18 | 7 | 250965 | 42 | 29701464 |
Conus medullaris syndrome | 13.23 | 11.18 | 5 | 250967 | 11 | 29701495 |
Echinococciasis | 13.23 | 11.18 | 5 | 250967 | 11 | 29701495 |
Bone tuberculosis | 13.21 | 11.18 | 15 | 250957 | 313 | 29701193 |
Hyperthermia | 13.20 | 11.18 | 42 | 250930 | 10057 | 29691449 |
Neoplasm recurrence | 13.20 | 11.18 | 40 | 250932 | 1827 | 29699679 |
Q fever | 13.19 | 11.18 | 10 | 250962 | 121 | 29701385 |
Capnocytophaga infection | 13 | 11.18 | 7 | 250965 | 44 | 29701462 |
Elbow operation | 12.99 | 11.18 | 10 | 250962 | 124 | 29701382 |
Haemodynamic instability | 12.99 | 11.18 | 30 | 250942 | 7985 | 29693521 |
Pityriasis rubra pilaris | 12.98 | 11.18 | 8 | 250964 | 67 | 29701439 |
Arteriospasm coronary | 12.97 | 11.18 | 3 | 250969 | 2615 | 29698891 |
Respiratory failure | 12.97 | 11.18 | 700 | 250272 | 99942 | 29601564 |
Pleomorphic malignant fibrous histiocytoma | 12.95 | 11.18 | 4 | 250968 | 3 | 29701503 |
Ear canal stenosis | 12.93 | 11.18 | 5 | 250967 | 12 | 29701494 |
Rhinocerebral mucormycosis | 12.88 | 11.18 | 8 | 250964 | 68 | 29701438 |
Dyspnoea at rest | 12.88 | 11.18 | 3 | 250969 | 2603 | 29698903 |
Ammonia increased | 12.86 | 11.18 | 10 | 250962 | 4231 | 29697275 |
Herpes ophthalmic | 12.85 | 11.18 | 17 | 250955 | 417 | 29701089 |
Mitral valve incompetence | 12.85 | 11.18 | 62 | 250910 | 13172 | 29688334 |
Blood triglycerides increased | 12.85 | 11.18 | 67 | 250905 | 13950 | 29687556 |
Dialysis | 12.84 | 11.18 | 48 | 250924 | 10948 | 29690558 |
Electrocardiogram ST segment elevation | 12.81 | 11.18 | 11 | 250961 | 4431 | 29697075 |
Dysarthria | 12.81 | 11.18 | 179 | 250793 | 30311 | 29671195 |
Cyst rupture | 12.79 | 11.18 | 8 | 250964 | 69 | 29701437 |
Medulloblastoma recurrent | 12.79 | 11.18 | 8 | 250964 | 69 | 29701437 |
Tender joint count increased | 12.74 | 11.18 | 6 | 250966 | 27 | 29701479 |
Desmoid tumour | 12.73 | 11.18 | 9 | 250963 | 97 | 29701409 |
Immobile | 12.71 | 11.18 | 43 | 250929 | 2083 | 29699423 |
Superficial spreading melanoma stage unspecified | 12.69 | 11.18 | 11 | 250961 | 163 | 29701343 |
Faecal calprotectin abnormal | 12.69 | 11.18 | 11 | 250961 | 163 | 29701343 |
Suspected product quality issue | 12.69 | 11.18 | 11 | 250961 | 163 | 29701343 |
Amyotrophic lateral sclerosis | 12.68 | 11.18 | 27 | 250945 | 989 | 29700517 |
Lung abscess | 12.63 | 11.18 | 48 | 250924 | 2463 | 29699043 |
Stress ulcer | 12.60 | 11.18 | 8 | 250964 | 71 | 29701435 |
Listeriosis | 12.58 | 11.18 | 25 | 250947 | 871 | 29700635 |
Pancreatic neoplasm | 12.57 | 11.18 | 26 | 250946 | 933 | 29700573 |
Hypovolaemic shock | 12.52 | 11.18 | 22 | 250950 | 6478 | 29695028 |
Alcohol use | 12.51 | 11.18 | 8 | 250964 | 3747 | 29697759 |
Product storage error | 12.45 | 11.18 | 94 | 250878 | 6297 | 29695209 |
Diabetic neuropathy | 12.43 | 11.18 | 9 | 250963 | 3950 | 29697556 |
Acanthosis | 12.42 | 11.18 | 8 | 250964 | 73 | 29701433 |
Terminal ileitis | 12.40 | 11.18 | 6 | 250966 | 29 | 29701477 |
Antinuclear antibody positive | 12.39 | 11.18 | 33 | 250939 | 1399 | 29700107 |
Pneumatosis intestinalis | 12.38 | 11.18 | 50 | 250922 | 2640 | 29698866 |
Urinary incontinence | 12.36 | 11.18 | 87 | 250885 | 16853 | 29684653 |
Drug use disorder | 12.36 | 11.18 | 57 | 250915 | 3191 | 29698315 |
Enzyme level increased | 12.36 | 11.18 | 10 | 250962 | 134 | 29701372 |
Retroperitoneal haematoma | 12.35 | 11.18 | 3 | 250969 | 2529 | 29698977 |
Blood culture positive | 12.34 | 11.18 | 77 | 250895 | 4842 | 29696664 |
Viral vasculitis | 12.33 | 11.18 | 8 | 250964 | 74 | 29701432 |
Rheumatoid factor | 12.33 | 11.18 | 8 | 250964 | 74 | 29701432 |
Pulmonary air leakage | 12.29 | 11.18 | 9 | 250963 | 103 | 29701403 |
Herpes virus infection | 12.28 | 11.18 | 48 | 250924 | 2496 | 29699010 |
Cardiac failure acute | 12.25 | 11.18 | 38 | 250934 | 9171 | 29692335 |
Extrapulmonary tuberculosis | 12.21 | 11.18 | 9 | 250963 | 104 | 29701402 |
Rocky mountain spotted fever | 12.15 | 11.18 | 5 | 250967 | 15 | 29701491 |
Device leakage | 12.13 | 11.18 | 8 | 250964 | 3686 | 29697820 |
Gastric cancer | 12.12 | 11.18 | 77 | 250895 | 4873 | 29696633 |
Vitreous floaters | 12.12 | 11.18 | 6 | 250966 | 3238 | 29698268 |
Poikiloderma | 12.11 | 11.18 | 11 | 250961 | 174 | 29701332 |
Disseminated toxoplasmosis | 12.09 | 11.18 | 6 | 250966 | 31 | 29701475 |
Surgery | 12.08 | 11.18 | 149 | 250823 | 11402 | 29690104 |
Arthritis fungal | 12.06 | 11.18 | 8 | 250964 | 77 | 29701429 |
Parakeratosis | 12.06 | 11.18 | 10 | 250962 | 139 | 29701367 |
Muscle enzyme increased | 12.05 | 11.18 | 12 | 250960 | 214 | 29701292 |
Cerebral haematoma | 12.05 | 11.18 | 12 | 250960 | 4502 | 29697004 |
Bradykinesia | 12.03 | 11.18 | 6 | 250966 | 3224 | 29698282 |
Pseudolymphoma | 12.02 | 11.18 | 18 | 250954 | 497 | 29701009 |
Mood swings | 11.99 | 11.18 | 29 | 250943 | 7597 | 29693909 |
Peritonsillar abscess | 11.96 | 11.18 | 14 | 250958 | 302 | 29701204 |
Anaplastic large-cell lymphoma | 11.95 | 11.18 | 11 | 250961 | 177 | 29701329 |
Pulmonary arterial hypertension | 11.94 | 11.18 | 39 | 250933 | 9262 | 29692244 |
Soft tissue infection | 11.93 | 11.18 | 35 | 250937 | 1570 | 29699936 |
Laryngeal inflammation | 11.91 | 11.18 | 5 | 250967 | 16 | 29701490 |
Vaccination complication | 11.91 | 11.18 | 5 | 250967 | 16 | 29701490 |
Mesenteritis | 11.91 | 11.18 | 5 | 250967 | 16 | 29701490 |
C-reactive protein | 11.87 | 11.18 | 9 | 250963 | 109 | 29701397 |
Fusarium infection | 11.83 | 11.18 | 27 | 250945 | 1037 | 29700469 |
Prostatic specific antigen increased | 11.79 | 11.18 | 56 | 250916 | 11948 | 29689558 |
Pelvic cyst | 11.79 | 11.18 | 6 | 250966 | 33 | 29701473 |
Psoriasis area severity index increased | 11.79 | 11.18 | 6 | 250966 | 33 | 29701473 |
Nail injury | 11.79 | 11.18 | 6 | 250966 | 33 | 29701473 |
Mediastinal abscess | 11.79 | 11.18 | 6 | 250966 | 33 | 29701473 |
Skin injury | 11.77 | 11.18 | 26 | 250946 | 977 | 29700529 |
Encephalitis fungal | 11.76 | 11.18 | 11 | 250961 | 181 | 29701325 |
Inadequate analgesia | 11.75 | 11.18 | 4 | 250968 | 2704 | 29698802 |
Growth failure | 11.73 | 11.18 | 7 | 250965 | 55 | 29701451 |
Conjunctival haemorrhage | 11.69 | 11.18 | 4 | 250968 | 2696 | 29698810 |
Pathogen resistance | 11.69 | 11.18 | 34 | 250938 | 8376 | 29693130 |
Antiphospholipid syndrome | 11.69 | 11.18 | 16 | 250956 | 406 | 29701100 |
Electrolyte imbalance | 11.68 | 11.18 | 53 | 250919 | 11447 | 29690059 |
Coronary artery stenosis | 11.66 | 11.18 | 38 | 250934 | 9032 | 29692474 |
Oral pustule | 11.66 | 11.18 | 12 | 250960 | 223 | 29701283 |
Bowen's disease | 11.66 | 11.18 | 10 | 250962 | 146 | 29701360 |
Renal colic | 11.63 | 11.18 | 37 | 250935 | 1735 | 29699771 |
Skin toxicity | 11.62 | 11.18 | 56 | 250916 | 3193 | 29698313 |
Blood beta-D-glucan increased | 11.61 | 11.18 | 17 | 250955 | 460 | 29701046 |
Device deployment issue | 11.60 | 11.18 | 9 | 250963 | 113 | 29701393 |
Lower respiratory tract congestion | 11.59 | 11.18 | 26 | 250946 | 987 | 29700519 |
Hypersomnia | 11.58 | 11.18 | 52 | 250920 | 11264 | 29690242 |
Cryptococcal fungaemia | 11.57 | 11.18 | 8 | 250964 | 83 | 29701423 |
Oesophageal adenocarcinoma | 11.57 | 11.18 | 24 | 250948 | 863 | 29700643 |
Bundle branch block left | 11.57 | 11.18 | 16 | 250956 | 5188 | 29696318 |
Arteriosclerosis | 11.56 | 11.18 | 49 | 250923 | 10784 | 29690722 |
Intestinal transit time decreased | 11.55 | 11.18 | 4 | 250968 | 6 | 29701500 |
Cyanosis | 11.54 | 11.18 | 56 | 250916 | 11879 | 29689627 |
Ureaplasma infection | 11.52 | 11.18 | 11 | 250961 | 186 | 29701320 |
Pneumoconiosis | 11.49 | 11.18 | 13 | 250959 | 270 | 29701236 |
Abscess intestinal | 11.49 | 11.18 | 32 | 250940 | 1393 | 29700113 |
Cell marker increased | 11.47 | 11.18 | 17 | 250955 | 465 | 29701041 |
Tonsillitis bacterial | 11.47 | 11.18 | 5 | 250967 | 18 | 29701488 |
Gastric mucosal hypertrophy | 11.41 | 11.18 | 8 | 250964 | 85 | 29701421 |
Bladder cancer recurrent | 11.37 | 11.18 | 14 | 250958 | 319 | 29701187 |
Herpes simplex viraemia | 11.37 | 11.18 | 3 | 250969 | 0 | 29701506 |
Bronchitis fungal | 11.37 | 11.18 | 3 | 250969 | 0 | 29701506 |
Papillary tumour of renal pelvis | 11.37 | 11.18 | 3 | 250969 | 0 | 29701506 |
Bone callus excessive | 11.37 | 11.18 | 3 | 250969 | 0 | 29701506 |
Hepatitis B e antibody positive | 11.37 | 11.18 | 3 | 250969 | 0 | 29701506 |
Vascular wall hypertrophy | 11.37 | 11.18 | 3 | 250969 | 0 | 29701506 |
Chronic tonsillitis | 11.37 | 11.18 | 3 | 250969 | 0 | 29701506 |
Acute lymphocytic leukaemia (in remission) | 11.37 | 11.18 | 3 | 250969 | 0 | 29701506 |
Lymphadenitis | 11.37 | 11.18 | 36 | 250936 | 1684 | 29699822 |
Chromosomal deletion | 11.37 | 11.18 | 6 | 250966 | 36 | 29701470 |
Coronary arterial stent insertion | 11.37 | 11.18 | 11 | 250961 | 4183 | 29697323 |
Mucosal infection | 11.36 | 11.18 | 12 | 250960 | 230 | 29701276 |
Systemic lupus erythematosus | 11.36 | 11.18 | 47 | 250925 | 2509 | 29698997 |
Oxygen saturation decreased | 11.35 | 11.18 | 277 | 250695 | 43163 | 29658343 |
Chills | 11.31 | 11.18 | 493 | 250479 | 71845 | 29629661 |
Renal tubular necrosis | 11.29 | 11.18 | 78 | 250894 | 15173 | 29686333 |
Hepatosplenomegaly | 11.28 | 11.18 | 61 | 250911 | 3640 | 29697866 |
Pneumonia adenoviral | 11.28 | 11.18 | 10 | 250962 | 153 | 29701353 |
Candida osteomyelitis | 11.27 | 11.18 | 5 | 250967 | 19 | 29701487 |
Hypotonia | 11.26 | 11.18 | 26 | 250946 | 6922 | 29694584 |
Hip deformity | 11.26 | 11.18 | 8 | 250964 | 87 | 29701419 |
SARS-CoV-2 test negative | 11.24 | 11.18 | 6 | 250966 | 37 | 29701469 |
Pancreatic calcification | 11.24 | 11.18 | 11 | 250961 | 192 | 29701314 |
Eye irritation | 11.23 | 11.18 | 19 | 250953 | 5677 | 29695829 |
Tuberculosis liver | 11.22 | 11.18 | 7 | 250965 | 60 | 29701446 |
Extramedullary haemopoiesis | 11.22 | 11.18 | 7 | 250965 | 60 | 29701446 |
Encephalitis enteroviral | 11.22 | 11.18 | 10 | 250962 | 154 | 29701352 |
Infected dermal cyst | 11.22 | 11.18 | 15 | 250957 | 372 | 29701134 |
Anaplastic large cell lymphoma T- and null-cell types | 11.22 | 11.18 | 9 | 250963 | 119 | 29701387 |
Source | Code | Description |
---|---|---|
ATC | L01BA01 | ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS ANTINEOPLASTIC AGENTS ANTIMETABOLITES Folic acid analogues |
ATC | L04AX03 | ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS IMMUNOSUPPRESSANTS IMMUNOSUPPRESSANTS Other immunosuppressants |
MeSH PA | D000019 | Abortifacient Agents |
MeSH PA | D000020 | Abortifacient Agents, Nonsteroidal |
MeSH PA | D000963 | Antimetabolites |
MeSH PA | D000964 | Antimetabolites, Antineoplastic |
MeSH PA | D000970 | Antineoplastic Agents |
MeSH PA | D018501 | Antirheumatic Agents |
MeSH PA | D003879 | Dermatologic Agents |
MeSH PA | D004791 | Enzyme Inhibitors |
MeSH PA | D005493 | Folic Acid Antagonists |
MeSH PA | D007155 | Immunologic Factors |
MeSH PA | D007166 | Immunosuppressive Agents |
MeSH PA | D009676 | Noxae |
MeSH PA | D019384 | Nucleic Acid Synthesis Inhibitors |
MeSH PA | D012102 | Reproductive Control Agents |
FDA MoA | N0000000111 | Folic Acid Metabolism Inhibitors |
FDA EPC | N0000175584 | Folate Analog Metabolic Inhibitor |
CHEBI has role | CHEBI:35221 | antimetabolite |
CHEBI has role | CHEBI:35610 | cytostatic |
CHEBI has role | CHEBI:35705 | immunosuppressant |
CHEBI has role | CHEBI:35842 | antirheumatic agent |
CHEBI has role | CHEBI:50177 | dermatological agent |
CHEBI has role | CHEBI:50683 | 7,8-dihydrofolate reductase inhibitors |
CHEBI has role | CHEBI:50691 | abortifacient agent |
CHEBI has role | CHEBI:59517 | dna synthesis inhibitors |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Psoriasis | indication | 9014002 | DOID:8893 |
Rheumatoid arthritis | indication | 69896004 | DOID:7148 |
Acute lymphoid leukemia | indication | 91857003 | DOID:9952 |
Non-Hodgkin's lymphoma | indication | 118601006 | |
Burkitt's lymphoma | indication | 118617000 | |
Mycosis fungoides | indication | 118618005 | |
Malignant tumor of head and/or neck | indication | 255056009 | |
Osteosarcoma of bone | indication | 307576001 | DOID:3376 |
Malignant tumor of lung | indication | 363358000 | |
Juvenile rheumatoid arthritis | indication | 410795001 | |
Carcinoma of female breast | indication | 447782002 | |
Gestational trophoblastic neoplasia | indication | 609519004 | DOID:3590 |
Meningeal Leukemia | indication | ||
Polymyositis | off-label use | 31384009 | |
Vasculitis | off-label use | 31996006 | DOID:865 |
Psoriasis with arthropathy | off-label use | 33339001 | |
Systemic lupus erythematosus | off-label use | 55464009 | DOID:9074 |
Acute myeloid leukemia, disease | off-label use | 91861009 | |
Acute promyelocytic leukemia, FAB M3 | off-label use | 110004001 | |
Wegener's granulomatosis | off-label use | 195353004 | DOID:12132 |
Malignant tumor of urinary bladder | off-label use | 399326009 | DOID:11054 |
Systemic Dermatomyositis | off-label use | ||
Alcoholism | contraindication | 7200002 | |
Peptic ulcer | contraindication | 13200003 | DOID:750 |
Dehydration | contraindication | 34095006 | |
Fibrosis of lung | contraindication | 51615001 | DOID:3770 |
Acute nephropathy | contraindication | 58574008 | |
Hepatic failure | contraindication | 59927004 | |
Stomatitis | contraindication | 61170000 | DOID:9637 |
Interstitial pneumonia | contraindication | 64667001 | |
Ulcerative colitis | contraindication | 64766004 | DOID:8577 |
Leukopenia | contraindication | 84828003 | DOID:615 |
Kidney disease | contraindication | 90708001 | DOID:557 |
Disease of liver | contraindication | 235856003 | DOID:409 |
Anemia | contraindication | 271737000 | DOID:2355 |
Pregnancy, function | contraindication | 289908002 | |
Thrombocytopenic disorder | contraindication | 302215000 | DOID:1588 |
Bone marrow depression | contraindication | 307762000 | |
Ascites | contraindication | 389026000 | |
Gastric ulcer | contraindication | 397825006 | DOID:10808 |
Breastfeeding (mother) | contraindication | 413712001 | |
Disorder of immune function | contraindication | 414029004 | |
Methotrexate Toxicity | contraindication | ||
Pleural Effusions | contraindication |
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 3.61 | acidic |
pKa2 | 5.15 | acidic |
pKa3 | 12.92 | acidic |
pKa4 | 5.73 | Basic |
pKa5 | 4.51 | Basic |
pKa6 | 1.39 | Basic |
pKa7 | 0.75 | Basic |
pKa8 | 0.08 | Basic |
None
Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Exclusivity date | Description |
---|---|---|---|---|---|---|---|---|---|
EQ 2.5MG BASE/ML | XATMEP | AZURITY | N208400 | April 25, 2017 | RX | SOLUTION | ORAL | April 25, 2024 | TREATMENT OF OLIGOARTICULAR JUVENILE IDIOPATHIC ARTHRITIS (PERSISTENT OLIGOARTHRITIS, PSORIATIC JUVENILE IDIOPATHIC ARTHRITIS, ENTHESITIS-RELATED ARTHRITIS, OR UNDIFFERENTIATED ARTHRITIS) & POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS IN CHILDREN 0-16 YRS |
EQ 2.5MG BASE/ML | XATMEP | AZURITY | N208400 | April 25, 2017 | RX | SOLUTION | ORAL | April 25, 2024 | TREATMENT OF PEDIATRIC PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKEMIA AS A COMPONENT OF A COMBINULLTION CHEOMOTHERAPY MAINTENULLNCE REGIMEN |
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Dihydrofolate reductase | Enzyme | INHIBITOR | Ki | 8.92 | IUPHAR | DRUG LABEL | |||
Multidrug resistance-associated protein 4 | Transporter | WOMBAT-PK | |||||||
Multidrug resistance-associated protein 5 | Transporter | WOMBAT-PK | |||||||
ATP-binding cassette sub-family G member 2 | Transporter | WOMBAT-PK | |||||||
Multidrug resistance-associated protein 1 | Transporter | WOMBAT-PK | |||||||
Canalicular multispecific organic anion transporter 1 | Transporter | WOMBAT-PK | |||||||
Multidrug resistance protein 1 | Transporter | WOMBAT-PK | |||||||
Thymidylate synthase | Enzyme | Ki | 6.22 | CHEMBL | |||||
Folylpolyglutamate synthase, mitochondrial | Enzyme | IC50 | 5.49 | CHEMBL | |||||
Folate transporter 1 | Unclassified | Ki | 5.46 | CHEMBL | |||||
Folate receptor alpha | Membrane receptor | IC50 | 6.94 | CHEMBL | |||||
Proton-coupled folate transporter | Transporter | IC50 | 6.92 | CHEMBL | |||||
Folate receptor beta | Membrane receptor | IC50 | 6.97 | CHEMBL | |||||
Dihydrofolate reductase | Enzyme | IC50 | 9 | CHEMBL | |||||
Dihydrofolate reductase | Enzyme | IC50 | 8.89 | CHEMBL | |||||
Bifunctional dihydrofolate reductase-thymidylate synthase | Enzyme | IC50 | 8.85 | CHEMBL | |||||
Bifunctional dihydrofolate reductase-thymidylate synthase | Enzyme | Ki | 9.89 | CHEMBL | |||||
Thymidylate synthase | Enzyme | IC50 | 5.74 | CHEMBL | |||||
Dihydrofolate reductase | Unclassified | IC50 | 8.85 | CHEMBL | |||||
Thymidylate synthase | Enzyme | IC50 | 4.40 | CHEMBL | |||||
Dihydrofolate reductase | Unclassified | IC50 | 8.77 | CHEMBL | |||||
Dihydrofolate reductase | Enzyme | Ki | 10.14 | CHEMBL | |||||
Dihydrofolate reductase | Enzyme | IC50 | 7.91 | CHEMBL | |||||
Dihydrofolate reductase | Unclassified | Ki | 10.68 | CHEMBL | |||||
Thymidylate synthase | Enzyme | Ki | 4.35 | CHEMBL | |||||
Dihydrofolate reductase | Enzyme | Ki | 5.41 | CHEMBL | |||||
Dihydrofolate reductase | Enzyme | IC50 | 7.72 | CHEMBL | |||||
Pteridine reductase 1 | Enzyme | Ki | 7.41 | CHEMBL |
ID | Source |
---|---|
4019828 | VUID |
N0000147916 | NUI |
D00142 | KEGG_DRUG |
7413-34-5 | SECONDARY_CAS_RN |
4017903 | VANDF |
4019828 | VANDF |
C0025677 | UMLSCUI |
CHEBI:44185 | CHEBI |
MTX | PDB_CHEM_ID |
CHEMBL34259 | ChEMBL_ID |
CHEMBL426 | ChEMBL_ID |
CHEMBL3244648 | ChEMBL_ID |
DB00563 | DRUGBANK_ID |
4112 | PUBCHEM_CID |
D008727 | MESH_DESCRIPTOR_UI |
4815 | IUPHAR_LIGAND_ID |
926 | INN_ID |
YL5FZ2Y5U1 | UNII |
287734 | RXNORM |
12261 | MMSL |
30391 | MMSL |
5077 | MMSL |
6313 | MMSL |
73119 | MMSL |
d00060 | MMSL |
002644 | NDDF |
002645 | NDDF |
387381009 | SNOMEDCT_US |
412247000 | SNOMEDCT_US |
68887009 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Methotrexate Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0054-4550 | TABLET | 2.50 mg | ORAL | ANDA | 28 sections |
Methotrexate Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0054-8550 | TABLET | 2.50 mg | ORAL | ANDA | 28 sections |
Methotrexate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9367 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 1 g | INTRA-ARTERIAL | ANDA | 23 sections |
Methotrexate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9516 | SOLUTION | 25 mg | INTRA-ARTERIAL | ANDA | 23 sections |
Methotrexate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9517 | SOLUTION | 25 mg | INTRA-ARTERIAL | ANDA | 23 sections |
Methotrexate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9518 | SOLUTION | 25 mg | INTRA-ARTERIAL | ANDA | 23 sections |
Methotrexate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9519 | SOLUTION | 25 mg | INTRA-ARTERIAL | ANDA | 23 sections |
Methotrexate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9830 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 1 g | INTRA-ARTERIAL | ANDA | 23 sections |
Methotrexate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-0014 | TABLET | 2.50 mg | ORAL | ANDA | 28 sections |
Methotrexate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0555-0572 | TABLET | 2.50 mg | ORAL | ANDA | 28 sections |
Methotrexate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0703-3671 | INJECTION, SOLUTION | 25 mg | INTRA-ARTERIAL | ANDA | 28 sections |
Methotrexate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0703-3675 | INJECTION, SOLUTION | 25 mg | INTRA-ARTERIAL | ANDA | 28 sections |
Methotrexate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0703-3678 | INJECTION, SOLUTION | 25 mg | INTRA-ARTERIAL | ANDA | 25 sections |
Methotrexate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0703-3678 | INJECTION, SOLUTION | 25 mg | INTRA-ARTERIAL | ANDA | 25 sections |
Methotrexate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-7141 | TABLET | 2.50 mg | ORAL | ANDA | 26 sections |
Methotrexate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16729-277 | INJECTION | 25 mg | INTRA-ARTERIAL | ANDA | 29 sections |
Methotrexate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16729-486 | TABLET | 2.50 mg | ORAL | ANDA | 30 sections |
Methotrexate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42291-505 | TABLET | 2.50 mg | ORAL | ANDA | 28 sections |
Methotrexate | Human Prescription Drug Label | 1 | 47335-235 | TABLET | 2.50 mg | ORAL | ANDA | 30 sections |
Methotrexate | Human Prescription Drug Label | 1 | 50090-3418 | TABLET | 2.50 mg | ORAL | ANDA | 30 sections |
Methotrexate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-5457 | TABLET | 2.50 mg | ORAL | ANDA | 28 sections |
Methotrexate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50268-527 | TABLET | 2.50 mg | ORAL | ANDA | 28 sections |
Methotrexate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51079-670 | TABLET | 2.50 mg | ORAL | ANDA | 25 sections |
Trexall | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51285-366 | TABLET, FILM COATED | 5 mg | ORAL | ANDA | 28 sections |
Trexall | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51285-367 | TABLET, FILM COATED | 7.50 mg | ORAL | ANDA | 28 sections |
Trexall | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51285-368 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 28 sections |
Trexall | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51285-369 | TABLET, FILM COATED | 15 mg | ORAL | ANDA | 28 sections |
Methotrexate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51407-121 | TABLET | 2.50 mg | ORAL | ANDA | 29 sections |
Xatmep | HUMAN PRESCRIPTION DRUG LABEL | 1 | 52652-2001 | SOLUTION | 2.50 mg | ORAL | NDA | 28 sections |
Otrexup | HUMAN PRESCRIPTION DRUG LABEL | 1 | 54436-010 | INJECTION, SOLUTION | 10 mg | SUBCUTANEOUS | NDA | 30 sections |